{"query_id": "mcsa_1000_1rtd_assembly1", "enzyme_name": "HIV-1 reverse transcriptase", "ec": ["2.7.7.49"], "controls": [{"chain": "A", "status": "reference_overlength", "selected": {"accession": "P03366", "alignment_score": 1091.0, "observed_coverage": 0.9981949458483754, "aligned_identity": 0.9909584086799277, "canonical_span": [600, 1153], "sequence": "MGARASVLSGGELDRWEKIRLRPGGKKKYKLKHIVWASRELERFAVNPGLLETSEGCRQILGQLQPSLQTGSEELRSLYNTVATLYCVHQRIEIKDTKEALDKIEEEQNKSKKKAQQAAADTGHSSQVSQNYPIVQNIQGQMVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRVHPVHAGPIAPGQMREPRGSDIAGTTSTLQEQIGWMTNNPPIPVGEIYKRWIILGLNKIVRMYSPTSILDIRQGPKEPFRDYVDRFYKTLRAEQASQEVKNWMTETLLVQNANPDCKTILKALGPAATLEEMMTACQGVGGPGHKARVLAEAMSQVTNTATIMMQRGNFRNQRKMVKCFNCGKEGHTARNCRAPRKKGCWKCGKEGHQMKDCTERQANFLREDLAFLQGKAREFSSEQTRANSPTISSEQTRANSPTRRELQVWGRDNNSPSEAGADRQGTVSFNFPQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNFPISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSAGIRKILFLDGIDKAQDEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTIHTDNGSNFTSATVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRNPLWKGPAKLLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVASRQDED", "length": 1447, "reference_go_mf": ["GO:0004190", "GO:0003677", "GO:0034061", "GO:0003887", "GO:0004533", "GO:0008289", "GO:0003723", "GO:0003964", "GO:0004523", "GO:0005198", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_1001_5m4g_assembly1", "enzyme_name": "Prolidase (Xaa-Pro dipeptidase)", "ec": ["3.4.13.9"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P12955", "alignment_score": 962.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [5, 486], "sequence": "MAAATGPSFWLGNETLKVPLALFALNRQRLCERLRKNPAVQAGSIVVLQGGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTGKSTLFVPRLPASHATWMGKIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLTLRGVNTDSGSVCREASFDGISKFEVNNTILHPEIVECRVFKTDMELEVLRYTNKISSEAHREVMKAVKVGMKEYELESLFEHYCYSRGGMRHSSYTCICGSGENSAVLHYGHAGAPNDRTIQNGDMCLFDMGGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPEGVERIDEPGLRSLRTARHLQPGMVLTVEPGIYFIDHLLDEALADPARASFLNREVLQRFRGFGGVRIEEDVVVTDSGIELLTCVPRTVEEIEACMAGCDKAFTPFSGPK", "length": 493, "reference_go_mf": ["GO:0030145", "GO:0070006", "GO:0004181", "GO:0102009"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_b4954b1c252535a4e54d"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_1002_3aie_assembly1", "enzyme_name": "Glucansucrases (GTF-SI)", "ec": ["2.4.1.125"], "controls": [{"chain": "A", "status": "reference_overlength", "selected": {"accession": "P13470", "alignment_score": 1676.0, "observed_coverage": 1.0, "aligned_identity": 0.995260663507109, "canonical_span": [243, 1087], "sequence": "MEKKVRFKLRKVKKRWVTVSVASAVVTLTSLSGSLVKADSTDDRQQAVTESQASLVTTSEAAKETLTATDTSTATSATSQPTATVTDNVSTTNQSTNTTANTANFDVKPTTTSEQSKTDNSDKIIATSKAVNRLTATGKFVPANNNTAHSRTVTDKIVPIKPKIGKLKQPSSLSQDDIAALGNVKNIRKVNGKYYYYKEDGTLQKNYALNINGKTFFFDETGALSNNTLPSKKGNITNNDNTNSFAQYNQVYSTDAANFEHVDHYLTAESWYRPKYILKDGKTWTQSTEKDFRPLLMTWWPDQETQRQYVNYMNAQLGIHQTYNTATSPLQLNLAAQTIQTKIEEKITAEKNTNWLRQTISAFVKTQSAWNSDSEKPFDDHLQKGALLYSNNSKLTSQANSNYRILNRTPTNQTGKKDPRYTADRTIGGYEFLLANDVDNSNPVVQAEQLNWLHFLMNFGNIYANDPDANFDSIRVDAVDNVDADLLQIAGDYLKAAKGIHKNDKAANDHLSILEAWSYNDTPYLHDDGDNMINMDNRLRLSLLYSLAKPLNQRSGMNPLITNSLVNRTDDNAETAAVPSYSFIRAHDSEVQDLIRNIIRAEINPNVVGYSFTMEEIKKAFEIYNKDLLATEKKYTHYNTALSYALLLTNKSSVPRVYYGDMFTDDGQYMAHKTINYEAIETLLKARIKYVSGGQAMRNQQVGNSEIITSVRYGKGALKATDTGDRTTRTSGVAVIEGNNPSLRLKASDRVVVNMGAAHKNQAYRPLLLTTDNGIKAYHSDQEAAGLVRYTNDRGELIFTAADIKGYANPQVSGYLGVWVPVGAAADQDVRVAASTAPSTDGKSVHQNAALDSRVMFEGFSNFQAFATKKEEYTNVVIAKNVDKFAEWGVTDFEMAPQYVSSTDGSFLDSVIQNGYAFTDRYDLGISKPNKYGTADDLVKAIKALHSKGIKVMADWVPDQMYALPEKEVVTATRVDKYGTPVAGSQIKNTLYVVDGKSSGKDQQAKYGGAFLEELQAKYPELFARKQISTGVPMDPSVKIKQWSAKYFNGTNILGRGAGYVLKDQATNTYFSLVSDNTFLPKSLVNPNHGTSSSVTGLVFDGKGYVYYSTSGNQAKNAFISLGNNWYYFDNNGYMVTGAQSINGANYYFLSNGIQLRNAIYDNGNKVLSYYGNDGRRYENGYYLFGQQWRYFQNGIMAVGLTRIHGAVQYFDASGFQAKGQFITTADGKLRYFDRDSGNQISNRFVRNSKGEWFLFDHNGVAVTGTVTFNGQRLYFKPNGVQAKGEFIRDADGHLRYYDPNSGNEVRNRFVRNSKGEWFLFDHNGIAVTGTRVVNGQRLYFKSNGVQAKGELITERKGRIKYYDPNSGNEVRNRYVRTSSGNWYYFGNDGYALIGWHVVEGRRVYFDENGVYRYASHDQRNHWDYDYRRDFGRGSSSAVRFRHSRNGFFDNFFRF", "length": 1455, "reference_go_mf": ["GO:0047849", "GO:0046527"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_1003_3r6v_assembly1", "enzyme_name": "Aspartate Ammonia Lyase", "ec": ["4.3.1.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q9LCC6", "alignment_score": 913.0, "observed_coverage": 1.0, "aligned_identity": 0.9978165938864629, "canonical_span": [4, 462], "sequence": "MNTDVRIEKDFLGEKEIPKDAYYGVQTIRATENFPITGYRIHPELIKSLGIVKKSAALANMEVGLLDKEVGQYIVKAADEVIEGKWNDQFIVDPIQGGAGTSINMNANEVIANRALELMGEEKGNYSKISPNSHVNMSQSTNDAFPTATHIAVLSLLNQLIETTKYMQQEFMKKADEFAGVIKMGRTHLQDAVPILLGQEFEAYARVIARDIERIANTRNNLYDINMGATAVGTGLNADPEYISIVTEHLAKFSGHPLRSAQHLVDATQNTDCYTEVSSALKVCMINMSKIANDLRLMASGPRAGLSEIVLPARQPGSSIMPGKVNPVMPEVMNQVAFQVFGNDLTITSASEAGQFELNVMEPVLFFNLIQSISIMTNVFKSFTENCLKGIKANEERMKEYVEKSIGIITAINPHVGYETAAKLAREAYLTGESIRELCIKYGVLTEEQLNEILNPYEMTHPGIAGRK", "length": 468, "reference_go_mf": ["GO:0008797"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_d711ef2890ecfa3ec7a9"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "Q9LCC6", "alignment_score": 921.0, "observed_coverage": 1.0, "aligned_identity": 0.9978354978354979, "canonical_span": [4, 466], "sequence": "MNTDVRIEKDFLGEKEIPKDAYYGVQTIRATENFPITGYRIHPELIKSLGIVKKSAALANMEVGLLDKEVGQYIVKAADEVIEGKWNDQFIVDPIQGGAGTSINMNANEVIANRALELMGEEKGNYSKISPNSHVNMSQSTNDAFPTATHIAVLSLLNQLIETTKYMQQEFMKKADEFAGVIKMGRTHLQDAVPILLGQEFEAYARVIARDIERIANTRNNLYDINMGATAVGTGLNADPEYISIVTEHLAKFSGHPLRSAQHLVDATQNTDCYTEVSSALKVCMINMSKIANDLRLMASGPRAGLSEIVLPARQPGSSIMPGKVNPVMPEVMNQVAFQVFGNDLTITSASEAGQFELNVMEPVLFFNLIQSISIMTNVFKSFTENCLKGIKANEERMKEYVEKSIGIITAINPHVGYETAAKLAREAYLTGESIRELCIKYGVLTEEQLNEILNPYEMTHPGIAGRK", "length": 468, "reference_go_mf": ["GO:0008797"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_d711ef2890ecfa3ec7a9"}, "alternative_alignments": []}, {"chain": "C", "status": "assigned", "selected": {"accession": "Q9LCC6", "alignment_score": 921.0, "observed_coverage": 1.0, "aligned_identity": 0.9978354978354979, "canonical_span": [4, 466], "sequence": "MNTDVRIEKDFLGEKEIPKDAYYGVQTIRATENFPITGYRIHPELIKSLGIVKKSAALANMEVGLLDKEVGQYIVKAADEVIEGKWNDQFIVDPIQGGAGTSINMNANEVIANRALELMGEEKGNYSKISPNSHVNMSQSTNDAFPTATHIAVLSLLNQLIETTKYMQQEFMKKADEFAGVIKMGRTHLQDAVPILLGQEFEAYARVIARDIERIANTRNNLYDINMGATAVGTGLNADPEYISIVTEHLAKFSGHPLRSAQHLVDATQNTDCYTEVSSALKVCMINMSKIANDLRLMASGPRAGLSEIVLPARQPGSSIMPGKVNPVMPEVMNQVAFQVFGNDLTITSASEAGQFELNVMEPVLFFNLIQSISIMTNVFKSFTENCLKGIKANEERMKEYVEKSIGIITAINPHVGYETAAKLAREAYLTGESIRELCIKYGVLTEEQLNEILNPYEMTHPGIAGRK", "length": 468, "reference_go_mf": ["GO:0008797"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_d711ef2890ecfa3ec7a9"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_1004_3lkk_assembly1", "enzyme_name": "isopentenyl phosphate kinase (IPK)", "ec": ["2.7.4.26"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q9HLX1", "alignment_score": 452.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 245], "sequence": "MMILKIGGSVITDKSAYRTARTYAIRSIVKVLSGIEDLVCVVHGGGSFGHIKAMEFGLPGPKNPRSSIGYSIVHRDMENLDLMVIDAMIEMGMRPISVPISALRYDGRFDYTPLIRYIDAGFVPVSYGDVYIKDEHSYGIYSGDDIMADMAELLKPDVAVFLTDVDGIYSKDPKRNPDAVLLRDIDTNITFDRVQNDVTGGIGKKFESMVKMKSSVKNGVYLINGNHPERIGDIGKESFIGTVIR", "length": 245, "reference_go_mf": ["GO:0102043", "GO:0016301"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_e8f0d84e5ab020d98ce1"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_100_1a4s_assembly1", "enzyme_name": "betaine-aldehyde dehydrogenase", "ec": ["1.2.1.8"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P56533", "alignment_score": 1006.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 503], "sequence": "AQLVDSMPSASTGSVVVTDDLNYWGGRRIKSKDGATTEPVFEPATGRVLCQMVPCGAEEVDQAVQSAQAAYLKWSKMAGIERSRVMLEAARIIRERRDNIAKLEVINNGKTITEAEYDIDAAWQCIEYYAGLAPTLSGQHIQLPGGAFAYTRREPLGVCAGILAWNYPFMIAAWKCAPALACGNAVVFKPSPMTPVTGVILAEIFHEAGVPVGLVNVVQGGAETGSLLCHHPNVAKVSFTGSVPTGKKVMEMSAKTVKHVTLELGGKSPLLIFKDCELENAVRGALMANFLTQGQVCTNGTRVFVQREIMPQFLEEVVKRTKAIVVGDPLLTETRMGGLISKPQLDKVLGFVAQAKKEGARVLCGGEPLTPSDPKLKNGYFMSPCVLDNCRDDMTCVKEEIFGPVMSVLPFDTEEEVLQRANNTTFGLASGVFTRDISRAHRVAANLEAGTCYINTYSISPVEVPFGGYKMSGFGRENGQATVDYYSQLKTVIVEMGDVDSLF", "length": 503, "reference_go_mf": ["GO:0047105", "GO:0004029"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_94a651cea246f9f959c3"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_101_5fit_assembly1", "enzyme_name": "bis(5'-adenosyl)-triphosphatase", "ec": ["3.6.1.29"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P49789", "alignment_score": 220.5, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 147], "sequence": "MSFRFGQHLIKPSVVFLKTELSFALVNRKPVVPGHVLVCPLRPVERFHDLRPDEVADLFQTTQRVGTVVEKHFHGTSLTFSMQDGPEAGQTVKHVHVHVLPRKAGDFHRNDSIYEELQKHDKEDFPASWRSEEEMAAEAAALRVYFQ", "length": 147, "reference_go_mf": ["GO:0043530", "GO:0047627", "GO:0047352", "GO:0047710", "GO:0042802", "GO:0031625"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_8612f9c80e351cfe2dc6"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_102_1fcb_assembly1", "enzyme_name": "L-lactate dehydrogenase (cytochrome)", "ec": ["1.1.2.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00175", "alignment_score": 974.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [80, 591], "sequence": "MLKYKPLLKISKNCEAAILRASKTRLNTIRAYGSTVPKSKSFEQDSRKRTQSWTALRVGAILAATSSVAYLNWHNGQIDNEPKLDMNKQKISPAEVAKHNKPDDCWVVINGYVYDLTRFLPNHPGGQDVIKFNAGKDVTAIFEPLHAPNVIDKYIAPEKKLGPLQGSMPPELVCPPYAPGETKEDIARKEQLKSLLPPLDNIINLYDFEYLASQTLTKQAWAYYSSGANDEVTHRENHNAYHRIFFKPKILVDVRKVDISTDMLGSHVDVPFYVSATALCKLGNPLEGEKDVARGCGQGVTKVPQMISTLASCSPEEIIEAAPSDKQIQWYQLYVNSDRKITDDLVKNVEKLGVKALFVTVDAPSLGQREKDMKLKFSNTKAGPKAMKKTNVEESQGASRALSKFIDPSLTWKDIEELKKKTKLPIVIKGVQRTEDVIKAAEIGVSGVVLSNHGGRQLDFSRAPIEVLAETMPILEQRNLKDKLEVFVDGGVRRGTDVLKALCLGAKGVGLGRPFLYANSCYGRNGVEKAIEILRDEIEMSMRLLGVTSIAELKPDLLDLSTLKARTVGVPNDVLYNEVYEGPTLTEFEDA", "length": 591, "reference_go_mf": ["GO:0020037", "GO:0004460"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_5872b9939ee3ecd54848"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_103_1vao_assembly1", "enzyme_name": "vanillyl-alcohol oxidase", "ec": ["1.1.3.38"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P56216", "alignment_score": 1092.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [5, 560], "sequence": "MSKTQEFRPLTLPPKLSLSDFNEFIQDIIRIVGSENVEVISSKDQIVDGSYMKPTHTHDPHHVMDQDYFLASAIVAPRNVADVQSIVGLANKFSFPLWPISIGRNSGYGGAAPRVSGSVVLDMGKNMNRVLEVNVEGAYCVVEPGVTYHDLHNYLEANNLRDKLWLDVPDLGGGSVLGNAVERGVGYTPYGDHWMMHSGMEVVLANGELLRTGMGALPDPKRPETMGLKPEDQPWSKIAHLFPYGFGPYIDGLFSQSNMGIVTKIGIWLMPNPRGYQSYLITLPKDGDLKQAVDIIRPLRLGMALQNVPTIRHILLDAAVLGDKRSYSSRTEPLSDEELDKIAKQLNLGRWNFYGALYGPEPIRRVLWETIKDAFSAIPGVKFYFPEDTPENSVLRVRDKTMQGIPTYDELKWIDWLPNGAHLFFSPIAKVSGEDAMMQYAVTKKRCQEAGLDFIGTFTVGMREMHHIVCIVFNKKDLIQKRKVQWLMRTLIDDCAANGWGEYRTHLAFMDQIMETYNWNNSSFLRFNEVLKNAVDPNGIIAPGKSGVWPSQYSHVTWKL", "length": 560, "reference_go_mf": ["GO:0004458", "GO:0008720", "GO:0071949", "GO:0018465"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_7585b4f49598f911cb94"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_104_1c9u_assembly1", "enzyme_name": "quinoprotein glucose dehydrogenase", "ec": ["1.1.5.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P13650", "alignment_score": 879.5, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [24, 474], "sequence": "MNKHLLAKIALLSAVQLVTLSAFADVPLTPSQFAKAKSENFDKKVILSNLNKPHALLWGPDNQIWLTERATGKILRVNPESGSVKTVFQVPEIVNDADGQNGLLGFAFHPDFKNNPYIYISGTFKNPKSTDKELPNQTIIRRYTYNKSTDTLEKPVDLLAGLPSSKDHQSGRLVIGPDQKIYYTIGDQGRNQLAYLFLPNQAQHTPTQQELNGKDYHTYMGKVLRLNLDGSIPKDNPSFNGVVSHIYTLGHRNPQGLAFTPNGKLLQSEQGPNSDDEINLIVKGGNYGWPNVAGYKDDSGYAYANYSAAANKSIKDLAQNGVKVAAGVPVTKESEWTGKNFVPPLKTLYTVQDTYNYNDPTCGEMTYICWPTVAPSSAYVYKGGKKAITGWENTLLVPSLKRGVIFRIKLDPTYSTTYDDAVPMFKSNNRYRDVIASPDGNVLYVLTDTAGNVQKDDGSVTNTLENPGSLIKFTYKAK", "length": 478, "reference_go_mf": ["GO:0008876"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_bcadb021e463fd453661"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_106_1w85_assembly1", "enzyme_name": "pyruvate dehydrogenase (acetyl-transferring)", "ec": ["1.2.4.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P21874", "alignment_score": 648.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 325], "sequence": "MAQMTMVQAITDALRIELKNDPNVLIFGEDVGVNGGVFRATEGLQAEFGEDRVFDTPLAESGIGGLAIGLALQGFRPVPEIQFFGFVYEVMDSICGQMARIRYRTGGRYHMPITIRSPFGGGVHTPELHSDSLEGLVAQQPGLKVVIPSTPYDAKGLLISAIRDNDPVIFLEHLKLYRSFRQEVPEGEYTIPIGKADIKREGKDITIIAYGAMVHESLKAAAELEKEGISAEVVDLRTVQPLDIETIIGSVEKTGRAIVVQEAQRQAGIAANVVAEINERAILSLEAPVLRVAAPDTVYPFAQAESVWLPNFKDVIETAKKVMNF", "length": 325, "reference_go_mf": ["GO:0004739"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_f52b542c071a0de3f869"}, "alternative_alignments": [{"accession": "P21873", "alignment_score": 9.0, "observed_coverage": 0.018518518518518517, "aligned_identity": 0.8333333333333334, "canonical_span": [317, 323], "length": 369, "reference_go_mf": ["GO:0004739"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}, {"chain": "B", "status": "assigned", "selected": {"accession": "P21873", "alignment_score": 730.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [4, 369], "sequence": "MGVKTFQFPFAEQLEKVAEQFPTFQILNEEGEVVNEEAMPELSDEQLKELMRRMVYTRILDQRSISLNRQGRLGFYAPTAGQEASQIASHFALEKEDFILPGYRDVPQIIWHGLPLYQAFLFSRGHFHGNQIPEGVNVLPPQIIIGAQYIQAAGVALGLKMRGKKAVAITYTGDGGTSQGDFYEGINFAGAFKAPAIFVVQNNRFAISTPVEKQTVAKTLAQKAVAAGIPGIQVDGMDPLAVYAAVKAARERAINGEGPTLIETLCFRYGPHTMSGDDPTRYRSKELENEWAKKDPLVRFRKFLEAKGLWSEEEENNVIEQAKEEIKEAIKKADETPKQKVTDLISIMFEELPFNLKEQYEIYKEKESK", "length": 369, "reference_go_mf": ["GO:0004739"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_c06a368e2f691da0f477"}, "alternative_alignments": [{"accession": "P21874", "alignment_score": 9.0, "observed_coverage": 0.01643835616438356, "aligned_identity": 0.8333333333333334, "canonical_span": [314, 320], "length": 325, "reference_go_mf": ["GO:0004739"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_107_1n62_assembly1", "enzyme_name": "aerobic carbon monoxide dehydrogenase", "ec": ["1.2.5.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P19919", "alignment_score": 1608.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [5, 809], "sequence": "MNIQTTVEPTSAERAEKLQGMGCKRKRVEDIRFTQGKGNYVDDVKLPGMLFGDFVRSSHAHARIKSIDTSKAKALPGVFAVLTAADLKPLNLHYMPTLAGDVQAVLADEKVLFQNQEVAFVVAKDRYVAADAIELVEVDYEPLPVLVDPFKAMEPDAPLLREDIKDKMTGAHGARKHHNHIFRWEIGDKEGTDATFAKAEVVSKDMFTYHRVHPSPLETCQCVASMDKIKGELTLWGTFQAPHVIRTVVSLISGLPEHKIHVIAPDIGGGFGNKVGAYSGYVCAVVASIVLGVPVKWVEDRMENLSTTSFARDYHMTTELAATKDGKILAMRCHVLADHGAFDACADPSKWPAGFMNICTGSYDMPVAHLAVDGVYTNKASGGVAYRCSFRVTEAVYAIERAIETLAQRLEMDSADLRIKNFIQPEQFPYMAPLGWEYDSGNYPLAMKKAMDTVGYHQLRAEQKAKQEAFKRGETREIMGIGISFFTEIVGAGPSKNCDILGVSMFDSAEIRIHPTGSVIARMGTKSQGQGHETTYAQIIATELGIPADDIMIEEGNTDTAPYGLGTYGSRSTPTAGAATAVAARKIKAKAQMIAAHMLEVHEGDLEWDVDRFRVKGLPEKFKTMKELAWASYNSPPPNLEPGLEAVNYYDPPNMTYPFGAYFCIMDIDVDTGVAKTRRFYALDDCGTRINPMIIEGQVHGGLTEAFAVAMGQEIRYDEQGNVLGASFMDFFLPTAVETPKWETDYTVTPSPHHPIGAKGVGESPHVGGVPCFSNAVNDAYAFLNAGHIQMPHDAWRLWKVGEQLGLHV", "length": 809, "reference_go_mf": ["GO:0008805", "GO:0043885", "GO:0005507", "GO:0005506", "GO:0030151"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_7eef7d97fac7efdc561c"}, "alternative_alignments": [{"accession": "P19920", "alignment_score": 9.0, "observed_coverage": 0.007462686567164179, "aligned_identity": 0.8333333333333334, "canonical_span": [193, 199], "length": 288, "reference_go_mf": ["GO:0008805", "GO:0071949"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, {"accession": "P19921", "alignment_score": 8.0, "observed_coverage": 0.004975124378109453, "aligned_identity": 1.0, "canonical_span": [35, 39], "length": 166, "reference_go_mf": ["GO:0008805", "GO:0051536", "GO:0046872"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_108_1ps9_assembly1", "enzyme_name": "2,4-dienoyl-CoA reductase (NADPH)", "ec": ["1.3.1.34"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P42593", "alignment_score": 1342.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 672], "sequence": "MSYPSLFAPLDLGFTTLKNRVLMGSMHTGLEEYPDGAERLAAFYAERARHGVALIVSGGIAPDLTGVGMEGGAMLNDASQIPHHRTITEAVHQEGGKIALQILHTGRYSYQPHLVAPSALQAPINRFVPHELSHEEILQLIDNFARCAQLAREAGYDGVEVMGSEGYLINEFLTLRTNQRSDQWGGDYRNRMRFAVEVVRAVRERVGNDFIIIYRLSMLDLVEDGGTFAETVELAQAIEAAGATIINTGIGWHEARIPTIATPVPRGAFSWVTRKLKGHVSLPLVTTNRINDPQVADDILSRGDADMVSMARPFLADAELLSKAQSGRADEINTCIGCNQACLDQIFVGKVTSCLVNPRACHETKMPILPAVQKKNLAVVGAGPAGLAFAINAAARGHQVTLFDAHSEIGGQFNIAKQIPGKEEFYETLRYYRRMIEVTGVTLKLNHTVTADQLQAFDETILASGIVPRTPPIDGIDHPKVLSYLDVLRDKAPVGNKVAIIGCGGIGFDTAMYLSQPGESTSQNIAGFCNEWGIDSSLQQAGGLSPQGMQIPRSPRQIVMLQRKASKPGQGLGKTTGWIHRTTLLSRGVKMIPGVSYQKIDDDGLHVVINGETQVLAVDNVVICAGQEPNRALAQPLIDSGKTVHLIGGCDVAMELDARRAIAQGTRLALEI", "length": 672, "reference_go_mf": ["GO:0008670", "GO:0051539", "GO:0071949", "GO:0010181"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_8aefa9c88fc02660e965"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_109_1d3g_assembly1", "enzyme_name": "dihydroorotate oxidase (class II)", "ec": ["1.3.5.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q02127", "alignment_score": 705.5, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [28, 395], "sequence": "MAWRHLKKRAQDAVIILGGGGLLFASYLMATGDERFYAEHLMPTLQGLLDPESAHRLAVRFTSLGLLPRARFQDSDMLEVRVLGHKFRNPVGIAAGFDKHGEAVDGLYKMGFGFVEIGSVTPKPQEGNPRPRVFRLPEDQAVINRYGFNSHGLSVVEHRLRARQQKQAKLTEDGLPLGVNLGKNKTSVDAAEDYAEGVRVLGPLADYLVVNVSSPNTAGLRSLQGKAELRRLLTKVLQERDGLRRVHRPAVLVKIAPDLTSQDKEDIASVVKELGIDGLIVTNTTVSRPAGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGRVPIIGVGGVSSGQDALEKIRAGASLVQLYTALTFWGPPVVGKVKRELEALLKEQGFGGVTDAIGADHRR", "length": 395, "reference_go_mf": ["GO:0106430"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_e3d665dad3dbf6901bc5"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_10_1mkb_assembly1", "enzyme_name": "3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase", "ec": ["4.2.1.59"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0A6Q3", "alignment_score": 342.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 172], "sequence": "MVDKRESYTKEDLLASGRGELFGAKGPQLPAPNMLMMDRVVKMTETGGNFDKGYVEAELDINPDLWFFGCHFIGDPVMPGCLGLDAMWQLVGFYLGWLGGEGKGRALGVGEVKFTGQVLPTAKKVTYRIHFKRIVNRRLIMGLADGEVLVDGRLIYTASDLKVGLFQDTSAF", "length": 172, "reference_go_mf": ["GO:0019171", "GO:0042803", "GO:0034017"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_670c632ae6c5f97a7c37"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P0A6Q3", "alignment_score": 342.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 172], "sequence": "MVDKRESYTKEDLLASGRGELFGAKGPQLPAPNMLMMDRVVKMTETGGNFDKGYVEAELDINPDLWFFGCHFIGDPVMPGCLGLDAMWQLVGFYLGWLGGEGKGRALGVGEVKFTGQVLPTAKKVTYRIHFKRIVNRRLIMGLADGEVLVDGRLIYTASDLKVGLFQDTSAF", "length": 172, "reference_go_mf": ["GO:0019171", "GO:0042803", "GO:0034017"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_670c632ae6c5f97a7c37"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_110_1c0p_assembly1", "enzyme_name": "D-amino-acid oxidase", "ec": ["1.4.3.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P80324", "alignment_score": 722.0, "observed_coverage": 0.9944903581267218, "aligned_identity": 1.0, "canonical_span": [0, 361], "sequence": "MHSQKRVVVLGSGVIGLSSALILARKGYSVHILARDLPEDVSSQTFASPWAGANWTPFMTLTDGPRQAKWEESTFKKWVELVPTGHAMWLKGTRRFAQNEDGLLGHWYKDITPNYRPLPSSECPPGAIGVTYDTLSVHAPKYCQYLARELQKLGATFERRTVTSLEQAFDGADLVVNATGLGAKSIAGIDDQAAEPIRGQTVLVKSPCKRCTMDSSDPASPAYIIPRPGGEVICGGTYGVGDWDLSVNPETVQRILKHCLRLDPTISSDGTIEGIEVLRHNVGLRPARRGGPRVEAERIVLPLDRTKSPLSLGRGSARAAKEKEVTLVHAYGFSSAGYQQSWGAAEDVAQLVDEAFQRYHGAARESKL", "length": 368, "reference_go_mf": ["GO:0003884", "GO:0047821", "GO:0071949", "GO:0043799"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_9469c9351a105ac82d8c"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_111_1ofd_assembly1", "enzyme_name": "glutamate synthase (ferredoxin)", "ec": ["1.4.7.1"], "controls": [{"chain": "A", "status": "reference_overlength", "selected": {"accession": "P55038", "alignment_score": 2955.0, "observed_coverage": 0.9993293091884641, "aligned_identity": 0.9986577181208054, "canonical_span": [36, 1542], "sequence": "MSFQYPLLAPMTNSSVATNSNQPFLGQPWLVEERDACGVGFIANLRGKPDHTLVEQALKALGCMEHRGGCSADNDSGDGAGVMTAIPRELLAQWFNTRNLPMPDGDRLGVGMVFLPQEPSAREVARAYVEEVVRLEKLTVLGWREVPVNSDVLGIQAKNNQPHIEQILVTCPEGCAGDELDRRLYIARSIIGKKLAEDFYVCSFSCRTIVYKGMVRSIILGEFYLDLKNPGYTSNFAVYHRRFSTNTMPKWPLAQPMRLLGHNGEINTLLGNINWMAAREKELEVSGWTKAELEALTPIVNQANSDSYNLDSALELLVRTGRSPLEAAMILVPEAYKNQPALKDYPEISDFHDYYSGLQEPWDGPALLVFSDGKIVGAGLDRNGLRPARYCITKDDYIVLGSEAGVVDLPEVDIVEKGRLAPGQMIAVDLAEQKILKNYQIKQQAAQKYPYGEWIKIQRQTVASDSFAEKTLFNDAQTVLQQQAAFGYTAEDVEMVVVPMASQGKEPTFCMGDDTPLAVLSHKPRLLYDYFKQRFAQVTNPPIDPLRENLVMSLAMFLGKRGNLLEPKAESARTIKLRSPLVNEVELQAIKTGQLQVAEVSTLYDLDGVNSLETALDNLVKTAIATVQAGAEILVLTDRPNGAILTENQSFIPPLLAVGAVHHHLIRAGLRLKASLIVDTAQCWSTHHFACLVGYGASAICPYLALESVRQWWLDEKTQKLMENGRLDRIDLPTALKNYRQSVEAGLFKILSKMGISLLASYHGAQIFEAIGLGAELVEYAFAGTTSRVGGLTIADVAGEVMVFHGMAFPEMAKKLENFGFVNYRPGGEYHMNSPEMSKSLHKAVAAYKVGGNGNNGEAYDHYELYRQYLKDRPVTALRDLLDFNADQPAISLEEVESVESIVKRFCTGGMSLGALSREAHETLAIAMNRLGAKSNSGEGGEDVVRYLTLDDVDSEGNSPTLPHLHGLQNGDTANSAIKQIASGRFGVTPEYLMSGKQLEIKMAQGAKPGEGGQLPGKKVSEYIAMLRRSKPGVTLISPPPHHDIYSIEDLAQLIYDLHQINPEAQVSVKLVAEIGIGTIAAGVAKANADIIQISGHDGGTGASPLSSIKHAGSPWELGVTEVHRVLMENQLRDRVLLRADGGLKTGWDVVMAALMGAEEYGFGSIAMIAEGCIMARVCHTNNCPVGVATQQERLRQRFKGVPGQVVNFFYFIAEEVRSLLAHLGYRSLDDIIGRTDLLKVRSDVQLSKTQNLTLDCLLNLPDTKQNRQWLNHEPVHSNGPVLDDDILADPDIQEAINHQTTATKTYRLVNTDRTVGTRLSGAIAKKYGNNGFEGNITLNFQGAAGQSFGAFNLDGMTLHLQGEANDYVGKGMNGGEIVIVPHPQASFAPEDNVIIGNTCLYGATGGNLYANGRAGERFAVRNSVGKAVIEGAGDHCCEYMTGGVIVVLGPVGRNVGAGMTGGLAYFLDEVGDLPEKINPEIITLQRITASKGEEQLKSLITAHVEHTGSPKGKAILANWSDYLGKFWQAVPPSEKDSPEANGDVSLTGEKTLTSV", "length": 1556, "reference_go_mf": ["GO:0016041"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_112_3dfr_assembly1", "enzyme_name": "dihydrofolate reductase (bacterial)", "ec": ["1.5.1.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00381", "alignment_score": 315.0, "observed_coverage": 1.0, "aligned_identity": 0.9814814814814815, "canonical_span": [1, 163], "sequence": "MTAFLWAQDRDGLIGKDGHLPWHLPDDLHYFRAQTVGKIMVVGRRTYESFPKRPLPERTNVVLTHQEDYQAQGAVVVHDVAAVFAYAKQHPDQELVIAGGAQIFTAFKDDVDTLLVTRLAGSFEGDTKMIPLNWDDFTKVSSRTVEDTNPALTHTYEVWQKKA", "length": 163, "reference_go_mf": ["GO:0004146", "GO:0050661"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_070957fef640dfedaa41"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_113_2gb0_assembly2", "enzyme_name": "sarcosine oxidase", "ec": ["1.5.3.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P40859", "alignment_score": 778.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 390], "sequence": "MSTHFDVIVVGAGSMGMAAGYQLAKQGVKTLLVDAFDPPHTNGSHHGDTRIIRHAYGEGREYVPLALRSQELWYELEKETHHKIFTKTGVLVFGPKGESAFVAETMEAAKEHSLTVDLLEGDEINKRWPGITVPENYNAIFEPNSGVLFSENCIRAYRELAEARGAKVLTHTRVEDFDISPDSVKIETANGSYTADKLIVSMGAWNSKLLSKLNLDIPLQPYRQVVGFFESDESKYSNDIDFPGFMVEVPNGIYYGFPSFGGCGLKLGYHTFGQKIDPDTINREFGVYPEDESNLRAFLEEYMPGANGELKRGAVCMYTKTLDEHFIIDLHPEHSNVVIAAGFSGHGFKFSSGVGEVLSQLALTGKTEHDISIFSINRPALKESLQKTTI", "length": 390, "reference_go_mf": ["GO:0050660", "GO:0008115"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_533d1fcd7e8a5e69f96b"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_114_2tmd_assembly1", "enzyme_name": "trimethylamine dehydrogenase", "ec": ["1.5.8.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P16099", "alignment_score": 1458.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 730], "sequence": "MARDPKHDILFEPIQIGPKTLRNRFYQVPHCIGAGSDKPGFQSAHRSVKAEGGWAALNTEYCSINPESDDTHRLSARIWDEGDVRNLKAMTDEVHKYGALAGVELWYGGAHAPNMESRATPRGPSQYASEFETLSYCKEMDLSDIAQVQQFYVDAAKRSRDAGFDIVYVYGAHSYLPLQFLNPYYNKRTDKYGGSLENRARFWLETLEKVKHAVGSDCAIATRFGVDTVYGPGQIEAEVDGQKFVEMADSLVDMWDITIGDIAEWGEDAGPSRFYQQGHTIPWVKLVKQVSKKPVLGVGRYTDPEKMIEIVTKGYADIIGCARPSIADPFLPQKVEQGRYDDIRVCIGCNVCISRWEIGGPPMICTQNATAGEEYRRGWHPEKFRQTKNKDSVLIVGAGPSGSEAARVLMESGYTVHLTDTAEKIGGHLNQVAALPGLGEWSYHRDYRETQITKLLKKNKESQLALGQKPMTADDVLQYGADKVIIATGARWNTDGTNCLTHDPIPGADASLPDQLTPEQVMDGKKKIGKRVVILNADTYFMAPSLAEKLATAGHEVTIVSGVHLANYMHFTLEYPNMMRRLHELHVEELGDHFCSRIEPGRMEIYNIWGDGSKRTYRGPGVSPRDANTSHRWIEFDSLVLVTGRHSECTLWNELKARESEWAENDIKGIYLIGDAEAPRLIADATFTGHRVAREIEEANPQIAIPYKRETIAWGTPHMPGGNFKIEYKV", "length": 730, "reference_go_mf": ["GO:0010181", "GO:0050470"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_2cc11687735c00e6017b"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_115_1w1o_assembly1", "enzyme_name": "cytokinin dehydrogenase", "ec": ["1.5.99.12"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q9T0N8", "alignment_score": 930.5, "observed_coverage": 1.0, "aligned_identity": 0.9979123173277662, "canonical_span": [39, 534], "sequence": "MAVVYYLLLAGLIACSHALAAGTPALGDDRGRPWPASLAALALDGKLRTDSNATAAASTDFGNITSALPAAVLYPSSTGDLVALLSAANSTPGWPYTIAFRGRGHSLMGQAFAPGGVVVNMASLGDAAAPPRINVSADGRYVDAGGEQVWIDVLRASLARGVAPRSWNDYLYLTVGGTLSNAGISGQAFRHGPQISNVLEMDVITGHGEMVTCSKQLNADLFDAVLGGLGQFGVITRARIAVEPAPARARWVRFVYTDFAAFSADQERLTAPRPGGGGASFGPMSYVEGSVFVNQSLATDLANTGFFTDADVARIVALAGERNATTVYSIEATLNYDNATAAAAAVDQELASVLGTLSYVEGFAFQRDVAYAAFLDRVHGEEVALNKLGLWRVPHPWLNMFVPRSRIADFDRGVFKGILQGTDIVGPLIVYPLNKSMWDDGMSAATPSEDVFYAVSLLFSSVAPNDLARLQEQNRRILRFCDLAGIQYKTYLARHTDRSDWVRHFGAAKWNRFVEMKNKYDPKRLLSPGQDIFN", "length": 534, "reference_go_mf": ["GO:0019139", "GO:0071949"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_7cbeb1470066ebd322ce"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_117_1amo_assembly1", "enzyme_name": "NADPH-hemoprotein reductase", "ec": ["1.6.2.4"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00388", "alignment_score": 1184.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [63, 678], "sequence": "MGDSHEDTSATMPEAVAEEVSLFSTTDMVLFSLIVGVLTYWFIFRKKKEEIPEFSKIQTTAPPVKESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCMATYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNKTYEHFNAMGKYVDQRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEFFGVEATGEESSIRQYELVVHEDMDVAKVYTGEMGRLKSYENQKPPFDAKNPFLAAVTANRKLNQGTERHLMHLELDISDSKIRYESGDHVAVYPANDSALVNQIGEILGADLDVIMSLNNLDEESNKKHPFPCPTTYRTALTYYLDITNPPRTNVLYELAQYASEPSEQEHLHKMASSSGEGKELYLSWVVEARRHILAILQDYPSLRPPIDHLCELLPRLQARYYSIASSSKVHPNSVHICAVAVEYEAKSGRVNKGVATSWLRAKEPAGENGGRALVPMFVRKSQFRLPFKSTTPVIMVGPGTGIAPFMGFIQERAWLREQGKEVGETLLYYGCRRSDEDYLYREELARFHKDGALTQLNVAFSREQAHKVYVQHLLKRDREHLWKLIHEGGAHIYVCGDARNMAKDVQNTFYDIVAEFGPMEHTQAVDYVKKLMTKGRYSLDVWS", "length": 678, "reference_go_mf": ["GO:0004128", "GO:0009055", "GO:0008047", "GO:0019899", "GO:0050660", "GO:0010181", "GO:0016787", "GO:0047726", "GO:0050661", "GO:0003958", "GO:0008941", "GO:0016491"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_5d2cee88ed9fb081fa7a"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_118_1wrr_assembly1", "enzyme_name": "urate oxidase", "ec": ["1.7.3.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q00511", "alignment_score": 588.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [2, 296], "sequence": "MSAVKAARYGKDNVRVYKVHKDEKTGVQTVYEMTVCVLLEGEIETSYTKADNSVIVATDSIKNTIYITAKQNPVTPPELFGSILGTHFIEKYNHIHAAHVNIVCHRWTRMDIDGKPHPHSFIRDSEEKRNVQVDVVEGKGIDIKSSLSGLTVLKSTNSQFWGFLRDEYTTLKETWDRILSTDVDATWQWKNFSGLQEVRSHVPKFDATWATAREVTLKTFAEDNSASVQATMYKMAEQILARQQLIETVEYSLPNKHYFEIDLSWHKGLQNTGKNAEVFAPQSDPNGLIKCTVGRSSLKSKL", "length": 302, "reference_go_mf": ["GO:0004846"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_cb5dbe78672345fa69aa"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "Q00511", "alignment_score": 588.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [2, 296], "sequence": "MSAVKAARYGKDNVRVYKVHKDEKTGVQTVYEMTVCVLLEGEIETSYTKADNSVIVATDSIKNTIYITAKQNPVTPPELFGSILGTHFIEKYNHIHAAHVNIVCHRWTRMDIDGKPHPHSFIRDSEEKRNVQVDVVEGKGIDIKSSLSGLTVLKSTNSQFWGFLRDEYTTLKETWDRILSTDVDATWQWKNFSGLQEVRSHVPKFDATWATAREVTLKTFAEDNSASVQATMYKMAEQILARQQLIETVEYSLPNKHYFEIDLSWHKGLQNTGKNAEVFAPQSDPNGLIKCTVGRSSLKSKL", "length": 302, "reference_go_mf": ["GO:0004846"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_cb5dbe78672345fa69aa"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_119_2c3m_assembly1", "enzyme_name": "pyruvate:ferredoxin oxidoreducatse", "ec": ["1.2.7.1"], "controls": [{"chain": "A", "status": "reference_overlength", "selected": {"accession": "P94692", "alignment_score": 2462.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 1232], "sequence": "MGKKMMTTDGNTATAHVAYAMSEVAAIYPITPSSTMGEEADDWAAQGRKNIFGQTLTIREMQSEAGAAGAVHGALAAGALTTTFTASQGLLLMIPNMYKISGELLPGVFHVTARAIAAHALSIFGDHQDIYAARQTGFAMLASSSVQEAHDMALVAHLAAIESNVPFMHFFDGFRTSHEIQKIEVLDYADMASLVNQKALAEFRAKSMNPEHPHVRGTAQNPDIYFQGREAANPYYLKVPGIVAEYMQKVASLTGRSYKLFDYVGAPDAERVIVSMGSSCETIEEVINHLAAKGEKIGLIKVRLYRPFVSEAFFAALPASAKVITVLDRTKEPGAPGDPLYLDVCSAFVERGEAMPKILAGRYGLGSKEFSPAMVKSVYDNMSGAKKNHFTVGIEDDVTGTSLPVDNAFADTTPKGTIQCQFWGLGADGTVGANKQAIKIIGDNTDLFAQGYFSYDSKKSGGITISHLRFGEKPIQSTYLVNRADYVACHNPAYVGIYDILEGIKDGGTFVLNSPWSSLEDMDKHLPSGIKRTIANKKLKFYNIDAVKIATDVGLGGRINMIMQTAFFKLAGVLPFEKAVDLLKKSIHKAYGKKGEKIVKMNTDAVDQAVTSLQEFKYPDSWKDAPAETKAEPMTNEFFKNVVKPILTQQGDKLPVSAFEADGRFPLGTSQFEKRGVAINVPQWVPENCIQCNQCAFVCPHSAILPVLAKEEELVGAPANFTALEAKGKELKGYKFRIQINTLDCMGCGNCADICPPKEKALVMQPLDTQRDAQVPNLEYAARIPVKSEVLPRDSLKGSQFQEPLMEFSGACSGCGETPYVRVITQLFGERMFIANATGCSSIWGASAPSMPYKTNRLGQGPAWGNSLFEDAAEYGFGMNMSMFARRTHLADLAAKALESDASGDVKEALQGWLAGKNDPIKSKEYGDKLKKLLAGQKDGLLGQIAAMSDLYTKKSVWIFGGDGWAYDIGYGGLDHVLASGEDVNVFVMDTEVYSNTGGQSSKATPTGAVAKFAAAGKRTGKKDLARMVMTYGYVYVATVSMGYSKQQFLKVLKEAESFPGPSLVIAYATCINQGLRKGMGKSQDVMNTAVKSGYWPLFRYDPRLAAQGKNPFQLDSKAPDGSVEEFLMAQNRFAVLDRSFPEDAKRLRAQVAHELDVRFKELEHMAATNIFESFAPAGGKADGSVDFGEGAEFCTRDDTPMMARPDSGEACDQNRAGTSEQQGDLSKRTKK", "length": 1232, "reference_go_mf": ["GO:0005506", "GO:0019164", "GO:0030976"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_11_1qum_assembly1", "enzyme_name": "deoxyribonuclease IV (phage-T4-induced)", "ec": ["3.1.21.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0A6C1", "alignment_score": 558.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 279], "sequence": "MKYIGAHVSAAGGLANAAIRAAEIDATAFALFTKNQRQWRAAPLTTQTIDEFKAACEKYHYTSAQILPHDSYLINLGHPVTEALEKSRDAFIDEMQRCEQLGLSLLNFHPGSHLMQISEEDCLARIAESINIALDKTQGVTAVIENTAGQGSNLGFKFEHLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPAECEKTFADFARTVGFKYLRGMHLNDAKSTFGSRVDRHHSLGEGNIGHDAFRWIMQDDRFDGIPLILETINPDIWAEEIAWLKAQQTEKAVA", "length": 285, "reference_go_mf": ["GO:0008296", "GO:0008833", "GO:0003677", "GO:0003906", "GO:0016791", "GO:0008081", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_58a07bd2933cccc61358"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_120_1zp3_assembly1", "enzyme_name": "methylenetetrahydrofolate reductase [NAD(P)H]", "ec": ["1.5.1.20"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0AEZ1", "alignment_score": 559.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [3, 294], "sequence": "MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTYGANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGDLPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRAITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFDGLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL", "length": 296, "reference_go_mf": ["GO:0071949", "GO:0106312", "GO:0004489", "GO:0051087"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_05191848ce0de194a1f2"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_121_1sox_assembly1", "enzyme_name": "sulfite oxidase", "ec": ["1.8.3.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P07850", "alignment_score": 885.0, "observed_coverage": 0.9848812095032398, "aligned_identity": 0.9846491228070176, "canonical_span": [2, 459], "sequence": "APSYPRYTREEVGRHRSPEERVWVTHGTDVFDVTDFVELHPGGPDKILLAAGGALEPFWALYAVHGEPHVLELLQQYKVGELSPDEAPAAPDAQDPFAGDPPRHPGLRVNSQKPFNAEPPAELLAERFLTPNELFFTRNHLPVPAVEPSSYRLRVDGPGGRTLSLSLAELRSRFPKHEVTATLQCAGNRRSEMSRVRPVKGLPWDIGAISTARWGGASLRDVLLHAGFPEELQGGEHVCFEGLDADPGGAPYGASIPYGRALSPAADVLLAYEMNGTELPRDHRFPVRVVVPGVVGARSVKWLRRVAVSPDESPSRWQQNDYKGFSPCVDWDTVDYRTAPAIQELPVQSAVTQPRPGAAVPPGELTVKGYAWSGGGREVVRVDVSLDGGRTWKVARLMGDKAPPGRAWAWALWELTVPVEAGTELEIVCKAVDSSYNVQPDSVAPIWNLRGVLSTAWHR", "length": 459, "reference_go_mf": ["GO:0020037", "GO:0030151", "GO:0043546", "GO:0098809", "GO:0008482"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_5119a6846a564005c53e"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_122_1fva_assembly1", "enzyme_name": "protein-methionine-S-oxide reductase (MsrA)", "ec": ["1.8.4.11"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P54149", "alignment_score": 400.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [28, 228], "sequence": "MLSATRRALQLFHSLFPIPRMGDSAAKIVSPQEALPGRKEPLVVAAKHHVNGNRTVEPFPEGTQMAVFGMGCFWGAERKFWTLKGVYSTQVGFAGGYTPNPTYKEVCSGKTGHAEVVRVVFQPEHISFEELLKVFWENHDPTQGMRQGNDHGSQYRSAIYPTSAEHVGAALKSKEDYQKVLSEHGFGLITTDIREGQTFYYAEDYHQQYLSKDPDGYCGLGGTGVSCPLGIKK", "length": 233, "reference_go_mf": ["GO:0033744", "GO:0008113"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_741b4efa38f32cdb82fe"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_123_1jnr_assembly1", "enzyme_name": "adenylyl-sulfate reductase", "ec": ["1.8.99.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "O28603", "alignment_score": 1281.0, "observed_coverage": 1.0, "aligned_identity": 0.9984423676012462, "canonical_span": [1, 643], "sequence": "MVYYPKKYELYKADEVPTEVVETDILIIGGGFSGCGAAYEAAYWAKLGGLKVTLVEKAAVERSGAVAQGLSAINTYIDLTGRSERQNTLEDYVRYVTLDMMGLAREDLVADYARHVDGTVHLFEKWGLPIWKTPDGKYVREGQWQIMIHGESYKPIIAEAAKMAVGEENIYERVFIFELLKDKNDPNAVAGAVGFSVREPKFYVFKAKAVILATGGATLLFRPRSTGEAAGRTWYAIFDTGSGYYMGLKAGAMLTQFEHRFIPFRFKDGYGPVGAWFLFFKCKAKNAYGEEYIKTRAAELEKYKPYGAAQPIPTPLRNHQVMLEIMDGNQPIYMHTEEALAELAGGDKKKLKHIYEEAFEDFLDMTVSQALLWACQNIDPQEQPSEAAPAEPYIMGSHSGEAGFWVCGPEDLMPEEYAKLFPLKYNRMTTVKGLFAIGDCAGANPHKFSSGSFTEGRIAAKAAVRFILEQKPNPEIDDAVVEELKKKAYAPMERFMQYKDLSTADDVNPEYILPWQGLVRLQKIMDEYAAGIATIYKTNEKMLQRALELLAFLKEDLEKLAARDLHELMRAWELVHRVWTAEAHVRHMLFRKETRWPGYYYRTDYPELNDEEWKCFVCSKYDAEKDEWTFEKVPYVQVIEWSF", "length": 643, "reference_go_mf": ["GO:0009055", "GO:0050660", "GO:0000104"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_f0ec297ccb71d7923aa7"}, "alternative_alignments": [{"accession": "O28604", "alignment_score": 10.0, "observed_coverage": 0.00778816199376947, "aligned_identity": 1.0, "canonical_span": [121, 126], "length": 150, "reference_go_mf": ["GO:0016491"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}, {"chain": "B", "status": "assigned", "selected": {"accession": "O28604", "alignment_score": 298.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 150], "sequence": "MPSFVNPEKCDGCKALERTACEYICPNDLMTLDKEKMKAYNREPDMCWECYSCVKMCPQGAIDVRGYVDYSPLGGACVPMRGTSDIMWTVKYRNGKVLRFKFAIRTTPWGSIQPFEGFPEPTEEALKSELLAGEPEIIGTSEFPQVKKKA", "length": 150, "reference_go_mf": ["GO:0016491"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_a098bb8272cbe1c3f440"}, "alternative_alignments": [{"accession": "O28603", "alignment_score": 10.0, "observed_coverage": 0.03355704697986577, "aligned_identity": 1.0, "canonical_span": [335, 340], "length": 643, "reference_go_mf": ["GO:0009055", "GO:0050660", "GO:0000104"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_124_1v54_assembly1", "enzyme_name": "cytochrome-c oxidase (AA3 type)", "ec": ["1.9.3.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00396", "alignment_score": 1026.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 514], "sequence": "MFINRWLFSTNHKDIGTLYLLFGAWAGMVGTALSLLIRAELGQPGTLLGDDQIYNVVVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMSQYQTPLFVWSVMITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPAMMWALGFIFLFTVGGLTGIVLANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFVHWFPLFSGYTLNDTWAKIHFAIMFVGVNMTFFPQHFLGLSGMPRRYSDYPDAYTMWNTISSMGSFISLTAVMLMVFIIWEAFASKREVLTVDLTTTNLEWLNGCPPPYHTFEEPTYVNLK", "length": 514, "reference_go_mf": ["GO:0004129", "GO:0020037"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_0d7b87e330ece0fd1df1"}, "alternative_alignments": [{"accession": "P68530", "alignment_score": 8.0, "observed_coverage": 0.007797270955165692, "aligned_identity": 1.0, "canonical_span": [212, 216], "length": 227, "reference_go_mf": ["GO:0005507", "GO:0004129"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_125_1bt3_assembly1", "enzyme_name": "catechol oxidase", "ec": ["1.10.3.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q9ZP19", "alignment_score": 664.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 341], "sequence": "APIQAPEISKCVVPPADLPPGAVVDNCCPPVASNIVDYKLPAVTTMKVRPAAHTMDKDAIAKFAKAVELMKALPADDPRNFYQQALVHCAYCNGGYDQVNFPDQEIQVHNSWLFFPFHRWYLYFYERILGKLIGDPSFGLPFWNWDNPGGMVLPDFLNDSTSSLYDSNRNQSHLPPVVVDLGYNGADTDVTDQQRITDNLALMYKQMVTNAGTAELFLGKAYRAGDAPSPGAGSIETSPHIPIHRWVGDPRNTNNEDMGNFYSAGRDIAFYCHHSNVDRMWTIWQQLAGKPRKRDYTDSDWLNATFLFYDENGQAVKVRIGDSLDNQKMGYKYAKTPLPWLDSKPVPTKKKGGYASKSKAPFVASVFPVTLDKVVQVKVARPKKSRSAEEKEAEEEILLIVGIEVEIDKYAKFDVYLNDSDDPSGGKDKAEYAGSFAHLPHKHKGMKKIRTTLSLGLNEPLEDLGAEDDDTILVTLAPKVGGGVVSVDNVKVVYGS", "length": 496, "reference_go_mf": ["GO:0004097", "GO:0005507"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_13aaff96aead06f7704e"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_126_2frv_assembly3", "enzyme_name": "cytochrome-c3 hydrogenase", "ec": ["1.12.2.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P12944", "alignment_score": 1048.0, "observed_coverage": 1.0, "aligned_identity": 0.9924528301886792, "canonical_span": [6, 536], "sequence": "MSEMQGNKIVVDPITRIEGHLRIEVEVEGGKIKNAWSMSTLFRGLEMILKGRDPRDAQHFTQRACGVCTYVHALASVRAVDNCVGVKIPENATLMRNLTMGAQYMHDHLVHFYHLHALDWVNVANALNADPAKAARLANDLSPRKTTTESLKAVQAKVKALVESGQLGIFTNAYFLGGHPAYVLPAEVDLIATAHYLEALRVQVKAARAMAIFGAKNPHTQFTVVGGCTNYDSLRPERIAEFRKLYKEVREFIEQVYITDLLAVAGFYKNWAGIGKTSNFLTCGEFPTDEYDLNSRYTPQGVIWGNDLSKVDDFNPDLIEEHVKYSWYEGADAHHPYKGVTKPKWTEFHGEDRYSWMKAPRYKGEAFEVGPLASVLVAYAKKHEPTVKAVDLVLKTLGVGPEALFSTLGRTAARGIQCLTAAQEVEVWLDKLEANVKAGKDDLYTDWQYPTESQGVGFVNAPRGMLSHWIVQRGGKIENFQHVVPSTWNLGPRCAERKLSAVEQALIGTPIADPKRPVEILRTVHSYDPCIACGVHVIDPESNQVHKFRIL", "length": 551, "reference_go_mf": ["GO:0047806", "GO:0008901", "GO:0016151"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_30c160f95c3699bd7de9"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_127_1hfe_assembly1", "enzyme_name": "ferredoxin hydrogenase", "ec": ["1.12.7.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P07598", "alignment_score": 792.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 397], "sequence": "MSRTVMERIEYEMHTPDPKADPDKLHFVQIDEAKCIGCDTCSQYCPTAAIFGEMGEPHSIPHIEACINCGQCLTHCPENAIYEAQSWVPEVEKKLKDGKVKCIAMPAPAVRYALGDAFGMPVGSVTTGKMLAALQKLGFAHCWDTEFTADVTIWEEGSEFVERLTKKSDMPLPQFTSCCPGWQKYAETYYPELLPHFSTCKSPIGMNGALAKTYGAERMKYDPKQVYTVSIMPCIAKKYEGLRPELKSSGMRDIDATLTTRELAYMIKKAGIDFAKLPDGKRDSLMGESTGGATIFGVTGGVMEAALRFAYEAVTGKKPDSWDFKAVRGLDGIKEATVNVGGTDVKVAVVHGAKRFKQVCDDVKAGKSPYHFIEYMACPGGCVCGGGQPVMPGVLEAMDRTTTRLYAGLKKRLAMASANKA", "length": 421, "reference_go_mf": ["GO:0008901", "GO:0005506", "GO:0051536"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_0f029cac6907fc4865ba"}, "alternative_alignments": [{"accession": "P07603", "alignment_score": 8.0, "observed_coverage": 0.010101010101010102, "aligned_identity": 1.0, "canonical_span": [16, 20], "length": 123, "reference_go_mf": ["GO:0009055", "GO:0008901", "GO:0005506", "GO:0051536"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_128_1ba3_assembly1", "enzyme_name": "Photinus-luciferin 4-monooxygenase (ATP-hydrolysing)", "ec": ["1.13.12.7"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P08659", "alignment_score": 1073.5, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [2, 544], "sequence": "MEDAKNIKKGPAPFYPLEDGTAGEQLHKAMKRYALVPGTIAFTDAHIEVNITYAEYFEMSVRLAEAMKRYGLNTNHRIVVCSENSLQFFMPVLGALFIGVAVAPANDIYNERELLNSMNISQPTVVFVSKKGLQKILNVQKKLPIIQKIIIMDSKTDYQGFQSMYTFVTSHLPPGFNEYDFVPESFDRDKTIALIMNSSGSTGLPKGVALPHRTACVRFSHARDPIFGNQIIPDTAILSVVPFHHGFGMFTTLGYLICGFRVVLMYRFEEELFLRSLQDYKIQSALLVPTLFSFFAKSTLIDKYDLSNLHEIASGGAPLSKEVGEAVAKRFHLPGIRQGYGLTETTSAILITPEGDDKPGAVGKVVPFFEAKVVDLDTGKTLGVNQRGELCVRGPMIMSGYVNNPEATNALIDKDGWLHSGDIAYWDEDEHFFIVDRLKSLIKYKGYQVAPAELESILLQHPNIFDAGVAGLPDDDAGELPAAVVVLEHGKTMTEKEIVDYVASQVTTAKKLRGGVVFVDEVPKGLTGKLDARKIREILIKAKKGGKSKL", "length": 550, "reference_go_mf": ["GO:0016405", "GO:0047077", "GO:0051087"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_abda0b3a5aa96aaa72c6"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_129_1os7_assembly2", "enzyme_name": "taurine dioxygenase", "ec": ["1.14.11.17"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P37610", "alignment_score": 560.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [2, 282], "sequence": "MSERLSITPLGPYIGAQISGADLTRPLSDNQFEQLYHAVLRHQVVFLRDQAITPQQQRALAQRFGELHIHPVYPHAEGVDEIIVLDTHNDNPPDNDNWHTDVTFIETPPAGAILAAKELPSTGGDTLWTSGIAAYEALSVPFRQLLSGLRAEHDFRKSFPEYKYRKTEEEHQRWREAVAKNPPLLHPVVRTHPVSGKQALFVNEGFTTRIVDVSEKESEALLSFLFAHITKPEFQVRWRWQPNDIAIWDNRVTQHYANADYLPQRRIMHRATILGDKPFYRAG", "length": 283, "reference_go_mf": ["GO:0008198", "GO:0042802", "GO:0000908"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_de97e179f681fef8af9d"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_12_1oth_assembly1", "enzyme_name": "ornithine carbamoyltransferase", "ec": ["2.1.3.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00480", "alignment_score": 639.0, "observed_coverage": 1.0, "aligned_identity": 0.9968847352024922, "canonical_span": [33, 354], "sequence": "MLFNLRILLNNAAFRNGHNFMVRNFRCGQPLQNKVQLKGRDLLTLKNFTGEEIKYMLWLSADLKFRIKQKGEYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGHPCFLTTQDIHLGVNESLTDTARVLSSMADAVLARVYKQSDLDTLAKEASIPIINGLSDLYHPIQILADYLTLQEHYSSLKGLTLSWIGDGNNILHSIMMSAAKFGMHLQAATPKGYEPDASVTKLAEQYAKENGTKLLLTNDPLEAAHGGNVLITDTWISMGQEEEKKKRLQAFQGYQVTMKTAKVAASDWTFLHCLPRKPEEVDDEVFYSPRSLVFPEAENRKWTIMAVMVSLLTDYSPQLQKPKF", "length": 354, "reference_go_mf": ["GO:0016597", "GO:0042802", "GO:0004585", "GO:0042301", "GO:0005543"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_35d9672d82f6d9568b8a"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_130_1ndo_assembly1", "enzyme_name": "naphthalene 1,2-dioxygenase", "ec": ["1.14.12.12"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0A110", "alignment_score": 894.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 447], "sequence": "MNYNNKILVSESGLSQKHLIHGDEELFQHELKTIFARNWLFLTHDSLIPAPGDYVTAKMGIDEVIVSRQNDGSIRAFLNVCRHRGKTLVSVEAGNAKGFVCSYHGWGFGSNGELQSVPFEKDLYGESLNKKCLGLKEVARVESFHGFIYGCFDQEAPPLMDYLGDAAWYLEPMFKHSGGLELVGPPGKVVIKANWKAPAENFVGDAYHVGWTHASSLRSGESIFSSLAGNAALPPEGAGLQMTSKYGSGMGVLWDGYSGVHSADLVPELMAFGGAKQERLNKEIGDVRARIYRSHLNCTVFPNNSMLTCSGVFKVWNPIDANTTEVWTYAIVEKDMPEDLKRRLADSVQRTFGPAGFWESDDNDNMETASQNGKKYQSRDSDLLSNLGFGEDVYGDAVYPGVVGKSAIGETSYRGFYRAYQAHVSSSNWAEFEHASSTWHTELTKTTDR", "length": 449, "reference_go_mf": ["GO:0051537", "GO:0005506", "GO:0018625"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_6b55207241ddff79ebd3"}, "alternative_alignments": [{"accession": "P0A112", "alignment_score": 6.0, "observed_coverage": 0.006711409395973154, "aligned_identity": 1.0, "canonical_span": [9, 12], "length": 194, "reference_go_mf": [], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}, {"chain": "B", "status": "assigned", "selected": {"accession": "P0A110", "alignment_score": 890.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 445], "sequence": "MNYNNKILVSESGLSQKHLIHGDEELFQHELKTIFARNWLFLTHDSLIPAPGDYVTAKMGIDEVIVSRQNDGSIRAFLNVCRHRGKTLVSVEAGNAKGFVCSYHGWGFGSNGELQSVPFEKDLYGESLNKKCLGLKEVARVESFHGFIYGCFDQEAPPLMDYLGDAAWYLEPMFKHSGGLELVGPPGKVVIKANWKAPAENFVGDAYHVGWTHASSLRSGESIFSSLAGNAALPPEGAGLQMTSKYGSGMGVLWDGYSGVHSADLVPELMAFGGAKQERLNKEIGDVRARIYRSHLNCTVFPNNSMLTCSGVFKVWNPIDANTTEVWTYAIVEKDMPEDLKRRLADSVQRTFGPAGFWESDDNDNMETASQNGKKYQSRDSDLLSNLGFGEDVYGDAVYPGVVGKSAIGETSYRGFYRAYQAHVSSSNWAEFEHASSTWHTELTKTTDR", "length": 449, "reference_go_mf": ["GO:0051537", "GO:0005506", "GO:0018625"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_6b55207241ddff79ebd3"}, "alternative_alignments": [{"accession": "P0A112", "alignment_score": 6.0, "observed_coverage": 0.006741573033707865, "aligned_identity": 1.0, "canonical_span": [9, 12], "length": 194, "reference_go_mf": [], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_131_1doc_assembly1", "enzyme_name": "4-hydroxybenzoate 3-monooxygenase", "ec": ["1.14.13.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P20586", "alignment_score": 788.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 394], "sequence": "MKTQVAIIGAGPSGLLLGQLLHKAGIDNVILERQTPDYVLGRIRAGVLEQGMVDLLREAGVDRRMARDGLVHEGVEIAFAGQRRRIDLKRLSGGKTVTVYGQTEVTRDLMEAREACGATTVYQAAEVRLHDLQGERPYVTFERDGERLRLDCDYIAGCDGFHGISRQSIPAERLKVFERVYPFGWLGLLADTPPVSHELIYANHPRGFALCSQRSATRSRYYVQVPLSEKVEDWSDERFWTELKARLPSEVAEKLVTGPSLEKSIAPLRSFVVEPMQHGRLFLAGDAAHIVPPTGAKGLNLAASDVSTLYRLLLKAYREGRGELLERYSAICLRRIWKAERFSWWMTSVLHRFPDTDAFSQRIQQTELEYYLGSEAGLATIAENYVGLPYEEIE", "length": 394, "reference_go_mf": ["GO:0106356", "GO:0018659", "GO:0071949", "GO:0050660"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_a279a5e4be6af89c712a"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_132_1luc_assembly1", "enzyme_name": "alkanal monooxygenase (FMN-linked)", "ec": ["1.14.14.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P07740", "alignment_score": 632.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 355], "sequence": "MKFGNFLLTYQPPELSQTEVMKRLVNLGKASEGCGFDTVWLLEHHFTEFGLLGNPYVAAAHLLGATETLNVGTAAIVLPTAHPVRQAEDVNLLDQMSKGRFRFGICRGLYDKDFRVFGTDMDNSRALMDCWYDLMKEGFNEGYIAADNEHIKFPKIQLNPSAYTQGGAPVYVVAESASTTEWAAERGLPMILSWIINTHEKKAQLDLYNEVATEHGYDVTKIDHCLSYITSVDHDSNRAKDICRNFLGHWYDSYVNATKIFDDSDQTKGYDFNKGQWRDFVLKGHKDTNRRIDYSYEINPVGTPEECIAIIQQDIDATGIDNICCGFEANGSEEEIIASMKLFQSDVMPYLKEKQ", "length": 355, "reference_go_mf": ["GO:0047646"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_b10d0dbadfaf5e0c4c7f"}, "alternative_alignments": [{"accession": "P07739", "alignment_score": 38.0, "observed_coverage": 0.5644171779141104, "aligned_identity": 0.40217391304347827, "canonical_span": [35, 219], "length": 324, "reference_go_mf": ["GO:0047646"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_133_1yrc_assembly1", "enzyme_name": "camphor 5-monooxygenase", "ec": ["1.14.15.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00183", "alignment_score": 810.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [10, 415], "sequence": "MTTETIQSNANLAPLPPHVPEHLVFDFDMYNPSNLSAGVQEAWAVLQESNVPDLVWTRCNGGHWIATRGQLIREAYEDYRHFSSECPFIPREAGEAYDFIPTSMDPPEQRQFRALANQVVGMPVVDKLENRIQELACSLIESLRPQGQCNFTEDYAEPFPIRIFMLLAGLPEEDIPHLKYLTDQMTRPDGSMTFAEAKEALYDYLIPIIEQRRQKPGTDAISIVANGQVNGRPITSDEAKRMCGLLLVGGLDTVVNFLSFSMEFLAKSPEHRQELIERPERIPAACEELLRRFSLVADGRILTSDYEFHGVQLKKGDQILLPQMLSGLDERENACPMHVDFSRQKVSHTTFGHGSHLCLGQHLARREIIVTLKEWLTRIPDFSIAPGAQIQHKSGIVSGVQALPLVWDPATTKAV", "length": 415, "reference_go_mf": ["GO:0018683", "GO:0020037", "GO:0005506"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_513201b5e9cd85ea1a2b"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_134_2toh_assembly1", "enzyme_name": "tyrosine 3-monooxygenase", "ec": ["1.14.16.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P04177", "alignment_score": 657.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [159, 498], "sequence": "MPTPSAPSPQPKGFRRAVSEQDAKQAEAVTSPRFIGRRQSLIEDARKEREAAAAAAAAAVASSEPGNPLEAVVFEERDGNAVLNLLFSLRGTKPSSLSRAVKVFETFEAKIHHLETRPAQRPLAGSPHLEYFVRFEVPSGDLAALLSSVRRVSDDVRSAREDKVPWFPRKVSELDKCHHLVTKFDPDLDLDHPGFSDQVYRQRRKLIAEIAFQYKHGEPIPHVEYTAEEIATWKEVYVTLKGLYATHACREHLEGFQLLERYCGYREDSIPQLEDVSRFLKERTGFQLRPVAGLLSARDFLASLAFRVFQCTQYIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASDEEIEKLSTVYWFTVEFGLCKQNGELKAYGAGLLSSYGELLHSLSEEPEVRAFDPDTAAVQPYQDQTYQPVYFVSESFNDAKDKLRNYASRIQRPFSVKFDPYTLAIDVLDSPHTIQRSLEGVQDELHTLAHALSAIS", "length": 498, "reference_go_mf": ["GO:0016597", "GO:0035240", "GO:0019899", "GO:0008199", "GO:0008198", "GO:0042802", "GO:0004497", "GO:0019825", "GO:0019904", "GO:0036094", "GO:0034617", "GO:0004511"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_515bd132cb3cb068288b"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_135_1sdw_assembly1", "enzyme_name": "peptidylglycine monooxygenase", "ec": ["1.14.17.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P14925", "alignment_score": 624.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [44, 356], "sequence": "MAGRARSGLLLLLLGLLALQSSCLAFRSPLSVFKRFKETTRSFSNECLGTIGPVTPLDASDFALDIRMPGVTPKESDTYFCMSMRLPVDEEAFVIDFKPRASMDTVHHMLLFGCNMPSSTGSYWFCDEGTCTDKANILYAWARNAPPTRLPKGVGFRVGGETGSKYFVLQVHYGDISAFRDNHKDCSGVSVHLTRVPQPLIAGMYLMMSVDTVIPPGEKVVNADISCQYKMYPMHVFAYRVHTHHLGKVVSGYRVRNGQWTLIGRQNPQLPQAFYPVEHPVDVTFGDILAARCVFTGEGRTEATHIGGTSSDEMCNLYIMYYMEAKYALSFMTCTKNVAPDMFRTIPAEANIPIPVKPDMVMMHGHHKEAENKEKSALMQQPKQGEEEVLEQGDFYSLLSKLLGEREDVHVHKYNPTEKTESGSDLVAEIANVVQKKDLGRSDAREGAEHEEWGNAILVRDRIHRFHQLESTLRPAESRAFSFQQPGEGPWEPEPSGDFHVEEELDWPGVYLLPGQVSGVALDSKNNLVIFHRGDHVWDGNSFDSKFVYQQRGLGPIEEDTILVIDPNNAEILQSSGKNLFYLPHGLSIDTDGNYWVTDVALHQVFKLDPHSKEGPLLILGRSMQPGSDQNHFCQPTDVAVEPSTGAVFVSDGYCNSRIVQFSPSGKFVTQWGEESSGSSPRPGQFSVPHSLALVPHLDQLCVADRENGRIQCFKTDTKEFVREIKHASFGRNVFAISYIPGFLFAVNGKPYFGDQEPVQGFVMNFSSGEIIDVFKPVRKHFDMPHDIVASEDGTVYIGDAHTNTVWKFTLTEKMEHRSVKKAGIEVQEIKEAEAVVEPKVENKPTSSELQKMQEKQKLSTEPGSGVSVVLITTLLVIPVLVLLAIVMFIRWKKSRAFGDHDRKLESSSGRVLGRFRGKGSGGLNLGNFFASRKGYSRKGFDRVSTEGSDQEKDEDDGTESEEEYSAPLPKPAPSS", "length": 976, "reference_go_mf": ["GO:0005509", "GO:0003682", "GO:0005507", "GO:0042802", "GO:0004598", "GO:0004504", "GO:0019901", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_561d25f18146a50ef546"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_136_1afr_assembly1", "enzyme_name": "acyl-[acyl-carrier-protein] desaturase", "ec": ["1.14.19.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P22337", "alignment_score": 690.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [51, 396], "sequence": "MALKLNPFLSQTQKLPSFALPPMASTRSPKFYMASTLKSGSKEVENLKKPFMPPREVHVQVTHSMPPQKIEIFKSLDNWAEENILVHLKPVEKCWQPQDFLPDPASDGFDEQVRELRERAKEIPDDYFVVLVGDMITEEALPTYQTMLNTLDGVRDETGASPTSWAIWTRAWTAEENRHGDLLNKYLYLSGRVDMRQIEKTIQYLIGSGMDPRTENSPYLGFIYTSFQERATFISHGNTARQAKEHGDIKLAQICGTIAADEKRHETAYTKIVEKLFEIDPDGTVLAFADMMRKKISMPAHLMYDGRDDNLFDHFSAVAQRLGVYTAKDYADILEFLVGRWKVDKLTGLSAEGQKAQDYVCRLPPRIRRLEERAQGRAKEAPTMPFSWIFDRQVKL", "length": 396, "reference_go_mf": ["GO:0045300"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_2df1f32143bb2d1d7692"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_138_2jcw_assembly1", "enzyme_name": "superoxide dismutase", "ec": ["1.15.1.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00445", "alignment_score": 306.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 154], "sequence": "MVQAVAVLKGDAGVSGVVKFEQASESEPTTVSYEIAGNSPNAERGFHIHEFGDATNGCVSAGPHFNPFKKTHGAPTDEVRHVGDMGNVKTDENGVAKGSFKDSLIKLIGPTSVVGRSVVIHAGQDDLGKGDTEESLKTGNAGPRPACGVIGLTN", "length": 154, "reference_go_mf": ["GO:0005507", "GO:0016670", "GO:0004784"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_becbb2d61fe453b05935"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_139_1v97_assembly1", "enzyme_name": "xanthine dehydrogenase (mammalian)", "ec": ["1.17.1.4"], "controls": [{"chain": "A", "status": "reference_overlength", "selected": {"accession": "P80457", "alignment_score": 2566.0, "observed_coverage": 1.0, "aligned_identity": 0.9992295839753467, "canonical_span": [2, 1332], "sequence": "MTADELVFFVNGKKVVEKNADPETTLLAYLRRKLGLRGTKLGCGEGGCGACTVMLSKYDRLQDKIIHFSANACLAPICTLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGIVMSMYTLLRNQPEPTVEEIEDAFQGNLCRCTGYRPILQGFRTFAKNGGCCGGNGNNPNCCMNQKKDHTVTLSPSLFNPEEFMPLDPTQEPIFPPELLRLKDVPPKQLRFEGERVTWIQASTLKELLDLKAQHPEAKLVVGNTEIGIEMKFKNQLFPMIICPAWIPELNAVEHGPEGISFGAACALSSVEKTLLEAVAKLPTQKTEVFRGVLEQLRWFAGKQVKSVASLGGNIITASPISDLNPVFMASGTKLTIVSRGTRRTVPMDHTFFPSYRKTLLGPEEILLSIEIPYSREDEFFSAFKQASRREDDIAKVTCGMRVLFQPGSMQVKELALCYGGMADRTISALKTTQKQLSKFWNEKLLQDVCAGLAEELSLSPDAPGGMIEFRRTLTLSFFFKFYLTVLKKLGKDSKDKCGKLDPTYTSATLLFQKDPPANIQLFQEVPNGQSKEDTVGRPLPHLAAAMQASGEAVYCDDIPRYENELFLRLVTSTRAHAKIKSIDVSEAQKVPGFVCFLSADDIPGSNETGLFNDETVFAKDTVTCVGHIIGAVVADTPEHAERAAHVVKVTYEDLPAIITIEDAIKNNSFYGSELKIEKGDLKKGFSEADNVVSGELYIGGQDHFYLETHCTIAIPKGEEGEMELFVSTQNAMKTQSFVAKMLGVPVNRILVRVKRMGGGFGGKETRSTLVSVAVALAAYKTGHPVRCMLDRNEDMLITGGRHPFLARYKVGFMKTGTIVALEVDHYSNAGNSRDLSHSIMERALFHMDNCYKIPNIRGTGRLCKTNLSSNTAFRGFGGPQALFIAENWMSEVAVTCGLPAEEVRWKNMYKEGDLTHFNQRLEGFSVPRCWDECLKSSQYYARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGALIHVYTDGSVLVSHGGTEMGQGLHTKMVQVASKALKIPISKIYISETSTNTVPNSSPTAASVSTDIYGQAVYEACQTILKRLEPFKKKNPDGSWEDWVMAAYQDRVSLSTTGFYRTPNLGYSFETNSGNAFHYFTYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAFVQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPTEFRVSLLRDCPNKKAIYASKAVGEPPLFLGASVFFAIKDAIRAARAQHTNNNTKELFRLDSPATPEKIRNACVDKFTTLCVTGAPGNCKPWSLRV", "length": 1332, "reference_go_mf": ["GO:0051537", "GO:0071949", "GO:0050660", "GO:0005506", "GO:0030151", "GO:0043546", "GO:0042803", "GO:0004854", "GO:0004855"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_141_1dii_assembly1", "enzyme_name": "4-cresol dehydrogenase (hydroxylating)", "ec": ["1.17.9.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P09788", "alignment_score": 1030.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [6, 521], "sequence": "MSEQNNAVLPKGVTQGEFNKAVQKFRALLGDDNVLVESDQLVPYNKIMMPVENAAHAPSAAVTATTVEQVQGVVKICNEHKIPIWTISTGRNFGYGSAAPVQRGQVILDLKKMNKIIKIDPEMCYALVEPGVTFGQMYDYIQENNLPVMLSFSAPSAIAGPVGNTMDRGVGYTPYGEHFMMQCGMEVVLANGDVYRTGMGGVPGSNTWQIFKWGYGPTLDGMFTQANYGICTKMGFWLMPKPPVFKPFEVIFEDEADIVEIVDALRPLRMSNTIPNSVVIASTLWEAGSAHLTRAQYTTEPGHTPDSVIKQMQKDTGMGAWNLYAALYGTQEQVDVNWKIVTDVFKKLGKGRIVTQEEAGDTQPFKYRAQLMSGVPNLQEFGLYNWRGGGGSMWFAPVSEARGSECKKQAAMAKRVLHKYGLDYVAEFIVAPRDMHHVIDVLYDRTNPEETKRADACFNELLDEFEKEGYAVYRVNTRFQDRVAQSYGPVKRKLEHAIKRAVDPNNILAPGRSGIDLNNDF", "length": 521, "reference_go_mf": ["GO:0018695", "GO:0004458", "GO:0008720", "GO:0071949"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_67469be6f55b952cad86"}, "alternative_alignments": [{"accession": "P09787", "alignment_score": 8.0, "observed_coverage": 0.013592233009708738, "aligned_identity": 0.7142857142857143, "canonical_span": [59, 66], "length": 113, "reference_go_mf": ["GO:0009055", "GO:0020037"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}, {"chain": "B", "status": "assigned", "selected": {"accession": "P09787", "alignment_score": 146.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [34, 107], "sequence": "MTFPFSGAAVKRMLVTGVVLPFGLLVAAGQAQADSQWGSGKNLYDKVCGHCHKPEVGVGPVLEGRGLPEAYIKDIVRNGFRAMPAFPASYVDDESLTQVAEYLSSLPAPAAQP", "length": 113, "reference_go_mf": ["GO:0009055", "GO:0020037"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_32d2701c883e0d293a9b"}, "alternative_alignments": [{"accession": "P09788", "alignment_score": 8.0, "observed_coverage": 0.0958904109589041, "aligned_identity": 0.7142857142857143, "canonical_span": [396, 403], "length": 521, "reference_go_mf": ["GO:0018695", "GO:0004458", "GO:0008720", "GO:0071949"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_142_1e6e_assembly1", "enzyme_name": "ferredoxin-NADP+ reductase (adrenodoxin-type)", "ec": ["1.18.1.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P08165", "alignment_score": 914.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [35, 492], "sequence": "MAPRCWRWWPWSSWTRTRLPPSRSIQNFGQHFSTQEQTPQICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGLVRFGVAPDHPEVKNVINTFTQTARSDRCAFYGNVEVGRDVTVQELQDAYHAVVLSYGAEDHQALDIPGEELPGVFSARAFVGWYNGLPENRELAPDLSCDTAVILGQGNVALDVARILLTPPDHLEKTDITEAALGALRQSRVKTVWIVGRRGPLQVAFTIKELREMIQLPGTRPMLDPADFLGLQDRIKEAARPRKRLMELLLRTATEKPGVEEAARRASASRAWGLRFFRSPQQVLPSPDGRRAAGIRLAVTRLEGIGEATRAVPTGDVEDLPCGLVLSSIGYKSRPIDPSVPFDPKLGVVPNMEGRVVDVPGLYCSGWVKRGPTGVITTTMTDSFLTGQILLQDLKAGHLPSGPRPGSAFIKALLDSRGVWPVSFSDWEKLDAEEVSRGQASGKPREKLLDPQEMLRLLGH", "length": 492, "reference_go_mf": ["GO:0004324", "GO:0050660", "GO:0050661"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_655ac9c900588d4f5a6e"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_143_1ljl_assembly1", "enzyme_name": "arsenate reductase", "ec": ["1.20.4.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0A006", "alignment_score": 260.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 131], "sequence": "MDKKTIYFICTGNSCRSQMAEGWGKEILGEGWNVYSAGIETHGVNPKAIEAMKEVDIDISNHTSDLIDNDILKQSDLVVTLCSDADNNCPILPPNVKKEHWGFDDPAGKEWSEFQRVRDEIKLAIEKFKLR", "length": 131, "reference_go_mf": ["GO:0030612", "GO:0004725"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_2097feee40b5520759da"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_144_1g8k_assembly3", "enzyme_name": "arsenite oxidase", "ec": ["1.20.9.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q7SIF4", "alignment_score": 1615.0, "observed_coverage": 0.9987834549878345, "aligned_identity": 0.9890377588306942, "canonical_span": [4, 825], "sequence": "MSRPNDRITLPPANAQRTNMTCHFCIVGCGYHVYKWPELQEGGRAPEQNALGLDFRKQLPPLAVTLTPAMTNVVTEHNGRRYNIMVVPDKACVVNSGLSSTRGGKMASYMYTPTGDGKQRLKAPRLYAADQWVDTTWDHAMALYAGLIKKTLDKDGPQGVFFSCFDHGGAGGGFENTWGTGKLMFSAIQTPMVRIHNRPAYNSECHATREMGIGELNNAYEDAQLADVIWSIGNNPYESQTNYFLNHWLPNLQGATTSKKKERFPNENFPQARIIFVDPRETPSVAIARHVAGNDRVLHLAIEPGTDTALFNGLFTYVVEQGWIDKPFIEAHTKGFDDAVKTNRLSLDECSNITGVPVDMLKRAAEWSYKPKASGQAPRTMHAYEKGIIWGNDNYVIQSALLDLVIATHNVGRRGTGCVRMGGHQEGYTRPPYPGDKKIYIDQELIKGKGRIMTWWGCNNFQTSNNAQALREAILQRSAIVKQAMQKARGATTEEMVDVIYEATQNGGLFVTSINLYPTKLAEAAHLMLPAAHPGEMNLTSMNGERRIRLSEKFMDPPGTAMADCLIAARIANALRDMYQKDGKAEMAAQFEGFDWKTEEDAFNDGFRRAGQPGAPAIDSQGGSTGHLVTYDRLRKSGNNGVQLPVVSWDESKGLVGTEMLYTEGKFDTDDGKAHFKPAPWNGLPATVQQQKDKYRFWLNNGRNNEVWQTAYHDQYNSLMQERYPMAYIEMNPDDCKQLDVTGGDIVEVYNDFGSTFAMVYPVAEIKRGQTFMLFGYVNGIQGDVTTDWTDRNIIPYYKGTWGDIRKVGSMEEFKRTVSFKSRRFA", "length": 826, "reference_go_mf": ["GO:0050611", "GO:0051536", "GO:0043546", "GO:0003954"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_da93b425f8db6c7d26b9"}, "alternative_alignments": [{"accession": "Q7SIF3", "alignment_score": 8.0, "observed_coverage": 0.004866180048661801, "aligned_identity": 1.0, "canonical_span": [31, 35], "length": 175, "reference_go_mf": ["GO:0051537", "GO:0050611"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}, {"chain": "B", "status": "assigned", "selected": {"accession": "Q7SIF3", "alignment_score": 230.0, "observed_coverage": 1.0, "aligned_identity": 0.9097744360902256, "canonical_span": [42, 175], "sequence": "MSDTINLTRRGFLKVSGSGVAVAATLSPIASANAQKAPADAGRTTLQYPATQVSVAKNLKANEPVSFTYPDTSSPCVAVKLGSPVPGGVGPNNDIVAYSVLCTHMGCPTSYDKSSKTFKCPCHFTEFDAEKAGQMICGQATENLPRVLLRYDEASDALTAVGVDGLIYGRQANVI", "length": 175, "reference_go_mf": ["GO:0051537", "GO:0050611"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_9f1cb889d27a6f5c201d"}, "alternative_alignments": [{"accession": "Q7SIF4", "alignment_score": 8.0, "observed_coverage": 0.07518796992481203, "aligned_identity": 0.6, "canonical_span": [563, 573], "length": 826, "reference_go_mf": ["GO:0050611", "GO:0051536", "GO:0043546", "GO:0003954"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_145_1odm_assembly1", "enzyme_name": "isopenicillin-N synthase", "ec": ["1.21.3.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P05326", "alignment_score": 658.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [2, 331], "sequence": "MGSVSKANVPKIDVSPLFGDDQAAKMRVAQQIDAASRDTGFFYAVNHGINVQRLSQKTKEFHMSITPEEKWDLAIRAYNKEHQDQVRAGYYLSIPGKKAVESFCYLNPNFTPDHPRIQAKTPTHEVNVWPDETKHPGFQDFAEQYYWDVFGLSSALLKGYALALGKEENFFARHFKPDDTLASVVLIRYPYLDPYPEAAIKTAADGTKLSFEWHEDVSLITVLYQSNVQNLQVETAAGYQDIEADDTGYLINCGSYMAHLTNNYYKAPIHRVKWVNAERQSLPFFVNLGYDSVIDPFDPREPNGKSDREPLSYGDYLQNGLVSLINKNGQT", "length": 331, "reference_go_mf": ["GO:0005506", "GO:0016216"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_b98315010bb98de3eefb"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_146_4v4e_assembly1", "enzyme_name": "pyrogallol hydroxytransferase", "ec": ["1.97.1.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P80563", "alignment_score": 1750.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 875], "sequence": "MGEVVRLTNSSTGGPVFVYVKDGKIIRMTPMDFDDAVDAPSWKIEARGKTFTPPRKTSIAPYTAGFKSMIYSDLRIPYPMKRKSFDPNGERNPQLRGAGLSKQDPWSDYERISWDEATDIVVAEINRIKHAYGPSAILSTPSSHHMWGNVGYRHSTYFRFMNMMGFTYADHNPDSWEGWHWGGMHMWGFSWRLGNPEQYDLLEDGLKHAEMIVFWSSDPETNSGIYAGFESNIRRQWLKDLGVDFVFIDPHMNHTARLVADKWFSPKIGTDHALSFAIAYTWLKEDSYDKEYVAANAHGFEEWADYVLGKTDGTPKTCEWAEEESGVPACEIRALARQWAKKNTYLAAGGLGGWGGACRASHGIEWARGMIALATMQGMGKPGSNMWSTTQGVPLDYEFYFPGYAEGGISGDCENSAAGFKFAWRMFDGKTTFPSPSNLNTSAGQHIPRLKIPECIMGGKFQWSGKGFAGGDISHQLHQYEYPAPGYSKIKMFWKYGGPHLGTMTATNRYAKMYTHDSLEFVVSQSIWFEGEVPFADIILPACTNFERWDISEFANCSGYIPDNYQLCNHRVISLQAKCIEPVGESMSDYEIYRLFAKKLNIEEMFSEGKDELAWCEQYFNATDMPKYMTWDEFFKKGYFVVPDNPNRKKTVALRWFAEGREKDTPDWGPRLNNQVCRKGLQTTTGKVEFIATSLKNFEEQGYIDEHRPSMHTYVPAWESQKHSPLAVKYPLGMLSPHPRFSMHTMGDGKNSYMNYIKDHRVEVDGYKYWIMRVNSIDAEARGIKNGDLIRAYNDRGSVILAAQVTECLQPGTVHSYESCAVYDPLGTAGKSADRGGCINILTPDRYISKYACGMANNTALVEIEKWDGDKYEIY", "length": 875, "reference_go_mf": ["GO:0009055", "GO:0030151", "GO:0043546", "GO:0018706"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_51693eede0c315cf6469"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_147_1ls3_assembly1", "enzyme_name": "serine hydroxymethyltransferase", "ec": ["2.1.2.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P07511", "alignment_score": 921.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [12, 484], "sequence": "MATAVNGAPRDAALWSSHEQMLAQPLKDSDAEVYDIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGGTEHIDELETLCQKRALQAYGLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMAYKVNPDTGYIDYDRLEENARLFHPKLIIAGTSCYSRNLDYGRLRKIADENGAYLMADMAHISGLVVAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRRGVRSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTPEFKEYQRQVVANCRALSAALVELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTVQIQDDTGPRATLKEFKEKLAGDEKHQRAVRALRQEVESFAALFPLPGLPGF", "length": 484, "reference_go_mf": ["GO:0004372", "GO:0120567", "GO:0008732", "GO:0005521", "GO:0048027", "GO:0000900", "GO:0050179", "GO:0042803", "GO:0030170", "GO:0070905", "GO:0004793"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_cdac014f22f7b61927dd"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P07511", "alignment_score": 877.5, "observed_coverage": 1.0, "aligned_identity": 0.9978021978021978, "canonical_span": [14, 484], "sequence": "MATAVNGAPRDAALWSSHEQMLAQPLKDSDAEVYDIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGGTEHIDELETLCQKRALQAYGLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMAYKVNPDTGYIDYDRLEENARLFHPKLIIAGTSCYSRNLDYGRLRKIADENGAYLMADMAHISGLVVAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRRGVRSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTPEFKEYQRQVVANCRALSAALVELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTVQIQDDTGPRATLKEFKEKLAGDEKHQRAVRALRQEVESFAALFPLPGLPGF", "length": 484, "reference_go_mf": ["GO:0004372", "GO:0120567", "GO:0008732", "GO:0005521", "GO:0048027", "GO:0000900", "GO:0050179", "GO:0042803", "GO:0030170", "GO:0070905", "GO:0004793"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_cdac014f22f7b61927dd"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_148_1onr_assembly1", "enzyme_name": "transaldolase (type I)", "ec": ["2.2.1.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0A870", "alignment_score": 632.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 317], "sequence": "MTDKLTSLRQYTTVVADTGDIAAMKLYQPQDATTNPSLILNAAQIPEYRKLIDDAVAWAKQQSNDRAQQIVDATDKLAVNIGLEILKLVPGRISTEVDARLSYDTEASIAKAKRLIKLYNDAGISNDRILIKLASTWQGIRAAEQLEKEGINCNLTLLFSFAQARACAEAGVFLISPFVGRILDWYKANTDKKEYAPAEDPGVVSVSEIYQYYKEHGYETVVMGASFRNIGEILELAGCDRLTIAPALLKELAESEGAIERKLSYTGEVKARPARITESEFLWQHNQDPMAVDKLAEGIRKFAIDQEKLEKMIGDLL", "length": 317, "reference_go_mf": ["GO:0004801", "GO:0016744"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_1a62546566024bce4c99"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_149_1ggt_assembly1", "enzyme_name": "protein-glutamine gamma-glutamyltransferase (eukaryotic)", "ec": ["2.3.2.13"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00488", "alignment_score": 1408.5, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [8, 730], "sequence": "MSETSRTAFGGRRAVPPNNSNAAEDDLPTVELQGVVPRGVNLQEFLNVTSVHLFKERWDTNKVDHHTDKYENNKLIVRRGQSFYVQIDFSRPYDPRRDLFRVEYVIGRYPQENKGTYIPVPIVSELQSGKWGAKIVMREDRSVRLSIQSSPKCIVGKFRMYVAVWTPYGVLRTSRNPETDTYILFNPWCEDDAVYLDNEKEREEYVLNDIGVIFYGEVNDIKTRSWSYGQFEDGILDTCLYVMDRAQMDLSGRGNPIKVSRVGSAMVNAKDDEGVLVGSWDNIYAYGVPPSAWTGSVDILLEYRSSENPVRYGQCWVFAGVFNTFLRCLGIPARIVTNYFSAHDNDANLQMDIFLEEDGNVNSKLTKDSVWNYHCWNEAWMTRPDLPVGFGGWQAVDSTPQENSDGMYRCGPASVQAIKHGHVCFQFDAPFVFAEVNSDLIYITAKKDGTHVVENVDATHIGKLIVTKQIGGDGMMDITDTYKFQEGQEEERLALETALMYGAKKPLNTEGVMKSRSNVDMDFEVENAVLGKDFKLSITFRNNSHNRYTITAYLSANITFYTGVPKAEFKKETFDVTLEPLSFKKEAVLIQAGEYMGQLLEQASLHFFVTARINETRDVLAKQKSTVLTIPEIIIKVRGTQVVGSDMTVTVEFTNPLKETLRNVWVHLDGPGVTRPMKKMFREIRPNSTVQWEEVCRPWVSGHRKLIASMSSDSLRHVYGELDVQIQRRPSM", "length": 732, "reference_go_mf": ["GO:0003810"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_46a764779f6a34087a12"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_14_1vnc_assembly1", "enzyme_name": "chloride peroxidase (vanadate dependent)", "ec": ["1.11.1.10"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P49053", "alignment_score": 1149.0, "observed_coverage": 1.0, "aligned_identity": 0.9982638888888888, "canonical_span": [2, 578], "sequence": "MGSVTPIPLPKIDEPEEYNTNYILFWNHVGLELNRVTHTVGGPLTGPPLSARALGMLHLAIHDAYFSICPPTDFTTFLSPDTENAAYRLPSPNGANDARQAVAGAALKMLSSLYMKPVEQPNPNPGANISDNAYAQLGLVLDRSVLEAPGGVDRESASFMFGEDVADVFFALLNDPRGASQEGYHPTPGRYKFDDEPTHPVVLIPVDPNNPNGPKMPFRQYHAPFYGKTTKRFATQSEHFLADPPGLRSNADETAEYDDAVRVAIAMGGAQALNSTKRSPWQTAQGLYWAYDGSNLIGTPPRFYNQIVRRIAVTYKKEEDLANSEVNNADFARLFALVDVACTDAGIFSWKEKWEFEFWRPLSGVRDDGRPDHGDPFWLTLGAPATNTNDIPFKPPFPAYPSGHATFGGAVFQMVRRYYNGRVGTWKDDEPDNIAIDMMISEELNGVNRDLRQPYDPTAPIEDQPGIVRTRIVRHFDSAWELMFENAISRIFLGVHWRFDAAAARDILIPTTTKDVYAVDNNGATVFQNVEDIRYTTRGTREDPEGLFPIGGVPLGIEIADEIFNNGLKPTPPEIQPMPQETPVQKPVGQQPVKGMWEEEQAPVVKEAP", "length": 609, "reference_go_mf": ["GO:0016691"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_291e22a931b361280619"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_150_1ndp_assembly1", "enzyme_name": "nucleoside-diphosphate kinase", "ec": ["2.7.4.6"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P22887", "alignment_score": 300.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [5, 155], "sequence": "MSTNKVNKERTFLAVKPDGVARGLVGEIIARYEKKGFVLVGLKQLVPTKDLAESHYAEHKERPFFGGLVSFITSGPVVAMVFEGKGVVASARLMIGVTNPLASAPGSIRGDFGVDVGRNIIHGSDSVESANREIALWFKPEELLTEVKPNPNLYE", "length": 155, "reference_go_mf": ["GO:0005524", "GO:0004550"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_d2ac6dc9b1412078f09f"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_151_1q0n_assembly1", "enzyme_name": "2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase", "ec": ["2.7.6.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P26281", "alignment_score": 316.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 159], "sequence": "MTVAYIAIGSNLASPLEQVNAALKALGDIPESHILTVSSFYRTPPLGPQDQPDYLNAAVALETSLAPEELLNHTQRIELQQGRVRKAERWGPRTLDLDIMLFGNEVINTERLTVPHYDMKNRGFMLWPLFEIAPELVFPDGEMLRQILHTRAFDKLNKW", "length": 159, "reference_go_mf": ["GO:0003848", "GO:0000287"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_85340f1c02b3bcc4c96a"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_152_1f80_assembly1", "enzyme_name": "holo-[acyl-carrier-protein] synthase", "ec": ["2.7.8.7"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P96618", "alignment_score": 231.0, "observed_coverage": 0.9915254237288136, "aligned_identity": 0.9914529914529915, "canonical_span": [2, 119], "sequence": "MIYGIGLDITELKRIASMAGRQKRFAERILTRSELDQYYELSEKRKNEFLAGRFAAKEAFSKAFGTGIGRQLSFQDIEIRKDQNGKPYIICTKLSQAAVHVSITHTKEYAAAQVVIERLSS", "length": 121, "reference_go_mf": ["GO:0008897", "GO:0000287"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_9263824188d36c50916a"}, "alternative_alignments": [{"accession": "P80643", "alignment_score": 6.0, "observed_coverage": 0.05084745762711865, "aligned_identity": 0.6666666666666666, "canonical_span": [37, 43], "length": 77, "reference_go_mf": ["GO:0000035", "GO:0000036"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}, {"chain": "B", "status": "assigned", "selected": {"accession": "P96618", "alignment_score": 231.0, "observed_coverage": 0.9915254237288136, "aligned_identity": 0.9914529914529915, "canonical_span": [2, 119], "sequence": "MIYGIGLDITELKRIASMAGRQKRFAERILTRSELDQYYELSEKRKNEFLAGRFAAKEAFSKAFGTGIGRQLSFQDIEIRKDQNGKPYIICTKLSQAAVHVSITHTKEYAAAQVVIERLSS", "length": 121, "reference_go_mf": ["GO:0008897", "GO:0000287"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_9263824188d36c50916a"}, "alternative_alignments": [{"accession": "P80643", "alignment_score": 6.0, "observed_coverage": 0.05084745762711865, "aligned_identity": 0.6666666666666666, "canonical_span": [37, 43], "length": 77, "reference_go_mf": ["GO:0000035", "GO:0000036"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}, {"chain": "C", "status": "assigned", "selected": {"accession": "P80643", "alignment_score": 140.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 75], "sequence": "MADTLERVTKIIVDRLGVDEADVKLEASFKEDLGADSLDVVELVMELEDEFDMEISDEDAEKIATVGDAVNYIQNQQ", "length": 77, "reference_go_mf": ["GO:0000035", "GO:0000036"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_d26f533df76038851732"}, "alternative_alignments": [{"accession": "P96618", "alignment_score": 6.0, "observed_coverage": 0.0821917808219178, "aligned_identity": 0.6666666666666666, "canonical_span": [6, 12], "length": 121, "reference_go_mf": ["GO:0008897", "GO:0000287"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_154_1hy3_assembly1", "enzyme_name": "estrone sulfotransferase", "ec": ["2.8.2.4"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P49888", "alignment_score": 564.5, "observed_coverage": 1.0, "aligned_identity": 0.9965156794425087, "canonical_span": [1, 290], "sequence": "MNSELDYYEKFEEVHGILMYKDFVKYWDNVEAFQARPDDLVIATYPKSGTTWVSEIVYMIYKEGDVEKCKEDVIFNRIPFLECRKENLMNGVKQLDEMNSPRIVKTHLPPELLPASFWEKDCKIIYLCRNAKDVAVSFYYFFLMVAGHPNPGSFPEFVEKFMQGQVPYGSWYKHVKSWWEKGKSPRVLFLFYEDLKEDIRKEVIKLIHFLERKPSEELVDRIIHHTSFQEMKNNPSTNYTTLPDEIMNQKLSPFMRKGITGDWKNHFTVALNEKFDKHYEQQMKESTLKFRTEI", "length": 294, "reference_go_mf": ["GO:0004062", "GO:0004304", "GO:0047894", "GO:0050294", "GO:0008146"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_0b217b90d0abf39b97e9"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_155_1t4c_assembly1", "enzyme_name": "formyl-CoA transferase", "ec": ["2.8.3.16"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "O06644", "alignment_score": 851.0, "observed_coverage": 1.0, "aligned_identity": 0.9976580796252927, "canonical_span": [1, 428], "sequence": "MTKPLDGINVLDFTHVQAGPACTQMMGFLGANVIKIERRGSGDMTRGWLQDKPNVDSLYFTMFNCNKRSIELDMKTPEGKELLEQMIKKADVMVENFGPGALDRMGFTWEYIQELNPRVILASVKGYAEGHANEHLKVYENVAQCSGGAAATTGFWDGPPTVSGAALGDSNSGMHLMIGILAALEMRHKTGRGQKVAVAMQDAVLNLVRIKLRDQQRLERTGILAEYPQAQPNFAFDRDGNPLSFDNITSVPRGGNAGGGGQPGWMLKCKGWETDADSYVYFTIAANMWPQICDMIDKPEWKDDPAYNTFEGRVDKLMDIFSFIETKFADKDKFEVTEWAAQYGIPCGPVMSMKELAHDPSLQKVGTVVEVVDEIRGNHLTVGAPFKFSGFQPEITRAPLLGEHTDEVLKELGLDDAKIKELHAKQVV", "length": 428, "reference_go_mf": ["GO:0033608"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_c78d86cd2671334d9d22"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "O06644", "alignment_score": 843.0, "observed_coverage": 1.0, "aligned_identity": 0.9976525821596244, "canonical_span": [1, 428], "sequence": "MTKPLDGINVLDFTHVQAGPACTQMMGFLGANVIKIERRGSGDMTRGWLQDKPNVDSLYFTMFNCNKRSIELDMKTPEGKELLEQMIKKADVMVENFGPGALDRMGFTWEYIQELNPRVILASVKGYAEGHANEHLKVYENVAQCSGGAAATTGFWDGPPTVSGAALGDSNSGMHLMIGILAALEMRHKTGRGQKVAVAMQDAVLNLVRIKLRDQQRLERTGILAEYPQAQPNFAFDRDGNPLSFDNITSVPRGGNAGGGGQPGWMLKCKGWETDADSYVYFTIAANMWPQICDMIDKPEWKDDPAYNTFEGRVDKLMDIFSFIETKFADKDKFEVTEWAAQYGIPCGPVMSMKELAHDPSLQKVGTVVEVVDEIRGNHLTVGAPFKFSGFQPEITRAPLLGEHTDEVLKELGLDDAKIKELHAKQVV", "length": 428, "reference_go_mf": ["GO:0033608"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_c78d86cd2671334d9d22"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_157_1qh5_assembly1", "enzyme_name": "hydroxyacylglutathione hydrolase", "ec": ["3.1.2.6"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q16775", "alignment_score": 520.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [48, 308], "sequence": "MVVGRGLLGRRSLAALGAACARRGLGPALLGVFCHTDLRKNLTVDEGTMKVEVLPALTDNYMYLVIDDETKEAAIVDPVQPQKVVDAARKHGVKLTTVLTTHHHWDHAGGNEKLVKLESGLKVYGGDDRIGALTHKITHLSTLQVGSLNVKCLATPCHTSGHICYFVSKPGGSEPPAVFTGDTLFVAGCGKFYEGTADEMCKALLEVLGRLPPDTRVYCGHEYTINNLKFARHVEPGNAAIREKLAWAKEKYSIGEPTVPSTLAEEFTYNPFMRVREKTVQQHAGETDPVTTMRAVRREKDQFKMPRD", "length": 308, "reference_go_mf": ["GO:0004416"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_885b20713ab5c7ca9779"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_159_1hzy_assembly1", "enzyme_name": "aryldialkylphosphatase", "ec": ["3.1.8.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0A434", "alignment_score": 662.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [34, 365], "sequence": "MQTRRVVLKSAAAAGTLLGGLAGCASVAGSIGTGDRINTVRGPITISEAGFTLTHEHICGSSAGFLRAWPEFFGSRKALAEKAVRGLRRARAAGVRTIVDVSTFDIGRDVSLLAEVSRAADVHIVAATGLWFDPPLSMRLRSVEELTQFFLREIQYGIEDTGIRAGIIKVATTGKATPFQELVLKAAARASLATGVPVTTHTAASQRDGEQQAAIFESEGLSPSRVCIGHSDDTDDLSYLTALAARGYLIGLDHIPHSAIGLEDNASASALLGIRSWQTRALLIKALIDQGYMKQILVSNDWLFGFSSYVTNIMDVMDRVNPDGMAFIPLRVIPFLREKGVPQETLAGITVTNPARFLSPTLRAS", "length": 365, "reference_go_mf": ["GO:0004063", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_9d1278b38575c3f1a16a"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_15_1znb_assembly1", "enzyme_name": "beta-lactamase (Class B1)", "ec": ["3.5.2.6"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P25910", "alignment_score": 440.5, "observed_coverage": 1.0, "aligned_identity": 0.9868421052631579, "canonical_span": [19, 249], "sequence": "MKTVFILISMLFPVAVMAQKSVKISDDISITQLSDKVYTYVSLAEIEGWGMVPSNGMIVINNHQAALLDTPINDAQTEMLVNWVTDSLHAKVTTFIPNHWHGDCIGGLGYLQRKGVQSYANQMTIDLAKEKGLPVPEHGFTDSLTVSLDGMPLQCYYLGGGHATDNIVVWLPTENILFGGCMLKDNQATSIGNISDADVTAWPKTLDKVKAKFPSARYVVPGHGDYGGTELIEHTKQIVNQYIESTSKP", "length": 249, "reference_go_mf": ["GO:0008800", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_2ff0c14c56db82fa440e"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_160_1ako_assembly1", "enzyme_name": "exodeoxyribonuclease III", "ec": ["3.1.11.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P09030", "alignment_score": 536.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 268], "sequence": "MKFVSFNINGLRARPHQLEAIVEKHQPDVIGLQETKVHDDMFPLEEVAKLGYNVFYHGQKGHYGVALLTKETPIAVRRGFPGDDEEAQRRIIMAEIPSLLGNVTVINGYFPQGESRDHPIKFPAKAQFYQNLQNYLETELKRDNPVLIMGDMNISPTDLDIGIGEENRKRWLRTGKCSFLPEEREWMDRLMSWGLVDTFRHANPQTADRFSWFDYRSKGFDDNRGLRIDLLLASQPLAECCVETGIDYEIRSMEKPSDHAPVWATFRR", "length": 268, "reference_go_mf": ["GO:0003677", "GO:0008311", "GO:0004519", "GO:0004527"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_c55e1e4508e0a98b6350"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_161_1en7_assembly1", "enzyme_name": "crossover junction endodeoxyribonuclease", "ec": ["3.1.22.4"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P13340", "alignment_score": 314.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 157], "sequence": "MLLTGKLYKEEKQKFYDAQNGKCLICQRELNPDVQANHLDHDHELNGPKAGKVRGLLCNLCNAAEGQMKHKFNRSGLKGQGVDYLEWLENLLTYLKSDYTQNNIHPNFVGDKSKEFSRLGKEEMMAEMLQRGFEYNESDTKTQLIASFKKQLRKSLK", "length": 157, "reference_go_mf": ["GO:0004519", "GO:0016787", "GO:0046872"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_f78d85d464e2aa4fe4d2"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P13340", "alignment_score": 314.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 157], "sequence": "MLLTGKLYKEEKQKFYDAQNGKCLICQRELNPDVQANHLDHDHELNGPKAGKVRGLLCNLCNAAEGQMKHKFNRSGLKGQGVDYLEWLENLLTYLKSDYTQNNIHPNFVGDKSKEFSRLGKEEMMAEMLQRGFEYNESDTKTQLIASFKKQLRKSLK", "length": 157, "reference_go_mf": ["GO:0004519", "GO:0016787", "GO:0046872"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_f78d85d464e2aa4fe4d2"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_162_1vas_assembly1", "enzyme_name": "deoxyribonuclease (pyrimidine dimer)", "ec": ["3.1.25.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P04418", "alignment_score": 271.0, "observed_coverage": 1.0, "aligned_identity": 0.9927007299270073, "canonical_span": [1, 138], "sequence": "MTRINLTLVSELADQHLMAEYRELPRVFGAVRKHVANGKRVRDFKISPTFILGAGHVTFFYDKLEFLRKRQIELIAECLKRGFNIKDTTVQDISDIPQEFRGDYIPHEASIAISQARLDEKIAQRPTWYKYYGKAIYA", "length": 138, "reference_go_mf": ["GO:0140078", "GO:0033959", "GO:0003906", "GO:0000704"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_50fba1fb2d9133329518"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_163_1rdd_assembly1", "enzyme_name": "ribonuclease HI", "ec": ["3.1.26.4"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0A7Y4", "alignment_score": 310.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 155], "sequence": "MLKQVEIFTDGSCLGNPGPGGYGAILRYRGREKTFSAGYTRTTNNRMELMAAIVALEALKEHCEVILSTDSQYVRQGITQWIHNWKKRGWKTADKKPVKNVDLWQRLDAALGQHQIKWEWVKGHAGHPENERCDELARAAAMNPTLEDTGYQVEV", "length": 155, "reference_go_mf": ["GO:0004519", "GO:0000287", "GO:0003676", "GO:0004523"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_243b1449a9686574c161"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_164_1ruv_assembly1", "enzyme_name": "ribonuclease 1", "ec": ["4.6.1.18"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P61823", "alignment_score": 248.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [26, 150], "sequence": "MALKSLVLLSLLVLVLLLVRVQPSLGKETAAAKFERQHMDSSTSAASSSNYCNQMMKSRNLTKDRCKPVNTFVHESLADVQAVCSQKNVACKNGQTNCYQSYSTMSITDCRETGSSKYPNCAYKTTQANKHIIVACEGNPYVPVHFDASV", "length": 150, "reference_go_mf": ["GO:0003676", "GO:0004522", "GO:0004540"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_9e7d7130805f2344b7b7"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_165_2sns_assembly1", "enzyme_name": "micrococcal nuclease", "ec": ["3.1.31.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00644", "alignment_score": 279.0, "observed_coverage": 1.0, "aligned_identity": 0.9929078014184397, "canonical_span": [82, 223], "sequence": "MLVMTEYLLSAGICMAIVSILLIGMAISNVSKGQYAKRFFFFATSCLVLTLVVVSSLSSSANASQTDNGVNRSGSEDPTVYSATSTKKLHKEPATLIKAIDGDTVKLMYKGQPMTFRLLLVDTPETKHPKKGVEKYGPEASAFTKKMVENAKKIEVEFDKGQRTDKYGRGLAYIYADGKMVNEALVRQGLAKVAYVYKPNNTHEQHLRKSEAQAKKEKLNIWSEDNADSGQ", "length": 231, "reference_go_mf": ["GO:1990599", "GO:0003676"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_2a8ffc15d94d456dbca7"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_166_1hs6_assembly1", "enzyme_name": "leukotriene-A4 hydrolase", "ec": ["3.3.2.6"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P09960", "alignment_score": 1220.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 611], "sequence": "MPEIVDTCSLASPASVCRTKHLHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDLTIEKVVINGQEVKYALGERQSYKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLTPEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETPDPEDPSRKIYKFIQKVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETESMLKIAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGETHPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTDDWKDFLYSYFKDKVDVLNQVDWNAWLYSPGLPPIKPNYDMTLTNACIALSQRWITAKEDDLNSFNATDLKDLSSHQLNEFLAQTLQRAPLPLGHIKRMQEVYNFNAINNSEIRFRWLRLCIQSKWEDAIPLALKMATEQGRMKFTRPLFKDLAAFDKSHDQAVRTYQEHKASMHPVTAMLVGKDLKVD", "length": 611, "reference_go_mf": ["GO:0004177", "GO:0004301", "GO:0004463", "GO:0070006", "GO:0008233", "GO:0003723", "GO:0045148", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_419e4dc8adbe6e5c40c2"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_167_1lok_assembly1", "enzyme_name": "bacterial leucyl aminopeptidase", "ec": ["3.4.11.10"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q01693", "alignment_score": 582.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [106, 397], "sequence": "MKYTKTLLAMVLSATFCQAYAEDKVWISIGADANQTVMKSGAESILPNSVASSGQVWVGQVDVAQLAELSHNMHEEHNRCGGYMVHPSAQSAMAASAMPTTLASFVMPPITQQATVTAWLPQVDASQITGTISSLESFTNRFYTTTSGAQASDWIASEWQALSASLPNASVKQVSHSGYNQKSVVMTITGSEAPDEWIVIGGHLDSTIGSHTNEQSVAPGADDDASGIAAVTEVIRVLSENNFQPKRSIAFMAYAAEEVGLRGSQDLANQYKSEGKNVVSALQLDMTNYKGSAQDVVFITDYTDSNFTQYLTQLMDEYLPSLTYGFDTCGYACSDHASWHNAGYPAAMPFESKFNDYNPRIHTTQDTLANSDPTGSHAKKFTQLGLAYAIEMGSATGDTPTPGNQLEDGVPVTDLSGSRGSNVWYTFELETQKNLQITTSGGYGDLDLYVKFGSKASKQNWDCRPYLSGNNEVCTFNNASPGTYSVMLTGYSNYSGASLKASTF", "length": 504, "reference_go_mf": ["GO:0008235"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_df3caa257c523841110f"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_168_1itq_assembly1", "enzyme_name": "membrane dipeptidase", "ec": ["3.4.13.19"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P16444", "alignment_score": 738.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [16, 385], "sequence": "MWSGWWLWPLVAVCTADFFRDEAERIMRDSPVIDGHNDLPWQLLDMFNNRLQDERANLTTLAGTHTNIPKLRAGFVGGQFWSVYTPCDTQNKDAVRRTLEQMDVVHRMCRMYPETFLYVTSSAGIRQAFREGKVASLIGVEGGHSIDSSLGVLRALYQLGMRYLTLTHSCNTPWADNWLVDTGDSEPQSQGLSPFGQRVVKELNRLGVLIDLAHVSVATMKATLQLSRAPVIFSHSSAYSVCASRRNVPDDVLRLVKQTDSLVMVNFYNNYISCTNKANLSQVADHLDHIKEVAGARAVGFGGDFDGVPRVPEGLEDVSKYPDLIAELLRRNWTEAEVKGALADNLLRVFEAVEQASNLTQAPEEEPIPLDQLGGSCRTHYGYSSGASSLHRHWGLLLASLAPLVLCLSLL", "length": 411, "reference_go_mf": ["GO:0008800", "GO:0016805", "GO:0034235", "GO:0070573", "GO:0008235", "GO:0072341", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_05d60a6f764021e918cb"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_169_1pfq_assembly1", "enzyme_name": "dipeptidyl-peptidase IV", "ec": ["3.4.14.5"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P27487", "alignment_score": 1456.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [38, 766], "sequence": "MKTPWKVLLGLLGAAALVTIITVPVVLLNKGTDDATADSRKTYTLTDYLKNTYRLKLYSLRWISDHEYLYKQENNILVFNAEYGNSSVFLENSTFDEFGHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEALTSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCFSLP", "length": 766, "reference_go_mf": ["GO:0045499", "GO:0008239", "GO:0042802", "GO:0002020", "GO:0042803", "GO:0004252", "GO:0008236", "GO:0005102", "GO:0008240", "GO:0001618"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_272729ea12e07654f922"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_16_1bc2_assembly1", "enzyme_name": "beta-lactamase (Class B1)", "ec": ["3.5.2.6"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P04190", "alignment_score": 424.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [36, 257], "sequence": "MKKNTLLKVGLCVGLLGTIQFVSTISSVQASQKVEKTVIKNETGTISISQLNKNVWVHTELGSFNGEAVPSNGLVLNTSKGLVLVDSSWDDKLTKELIEMVEKKFQKRVTDVIITHAHADRIGGIKTLKERGIKAHSTALTAELAKKNGYEEPLGDLQTVTNLKFGNMKVETFYPGKGHTEDNIVVWLPQYNILVGGCLVKSTSAKDLGNVADAYVNEWSTSIENVLKRYRNINAVVPGHGEVGDKGLLLHTLDLLK", "length": 257, "reference_go_mf": ["GO:0008800", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_9955276e67350b096848"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_170_1o8a_assembly1", "enzyme_name": "peptidyl-dipeptidase A", "ec": ["3.4.15.1"], "controls": [{"chain": "A", "status": "reference_overlength", "selected": {"accession": "P12821", "alignment_score": 1140.5, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [644, 1222], "sequence": "MGAASGRRGPGLLLPLPLLLLLPPQPALALDPGLQPGNFSADEAGAQLFAQSYNSSAEQVLFQSVAASWAHDTNITAENARRQEEAALLSQEFAEAWGQKAKELYEPIWQNFTDPQLRRIIGAVRTLGSANLPLAKRQQYNALLSNMSRIYSTAKVCLPNKTATCWSLDPDLTNILASSRSYAMLLFAWEGWHNAAGIPLKPLYEDFTALSNEAYKQDGFTDTGAYWRSWYNSPTFEDDLEHLYQQLEPLYLNLHAFVRRALHRRYGDRYINLRGPIPAHLLGDMWAQSWENIYDMVVPFPDKPNLDVTSTMLQQGWNATHMFRVAEEFFTSLELSPMPPEFWEGSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTRVTMDQLSTVHHEMGHIQYYLQYKDLPVSLRRGANPGFHEAIGDVLALSVSTPEHLHKIGLLDRVTNDTESDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPPSRYNFDWWYLRTKYQGICPPVTRNETHFDAGAKFHVPNVTPYIRYFVSFVLQFQFHEALCKEAGYEGPLHQCDIYRSTKAGAKLRKVLQAGSSRPWQEVLKDMVGLDALDAQPLLKYFQPVTQWLQEQNQQNGEVLGWPEYQWHPPLPDNYPEGIDLVTDEAEASKFVEEYDRTSQVVWNEYAEANWNYNTNITTETSKILLQKNMQIANHTLKYGTQARKFDVNQLQNTTIKRIIKKVQDLERAALPAQELEEYNKILLDMETTYSVATVCHPNGSCLQLEPDLTNVMATSRKYEDLLWAWEGWRDKAGRAILQFYPKYVELINQAARLNGYVDAGDSWRSMYETPSLEQDLERLFQELQPLYLNLHAYVRRALHRHYGAQHINLEGPIPAHLLGNMWAQTWSNIYDLVVPFPSAPSMDTTEAMLKQGWTPRRMFKEADDFFTSLGLLPVPPEFWNKSMLEKPTDGREVVCHASAWDFYNGKDFRIKQCTTVNLEDLVVAHHEMGHIQYFMQYKDLPVALREGANPGFHEAIGDVLALSVSTPKHLHSLNLLSSEGGSDEHDINFLMKMALDKIAFIPFSYLVDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRTQGDFDPGAKFHIPSSVPYIRYFVSFIIQFQFHEALCQAAGHTGPLHKCDIYQSKEAGQRLATAMKLGFSRPWPEAMQLITGQPNMSASAMLSYFKPLLDWLRTENELHGEKLGWPQYNWTPNSARSEGPLPDSGRVSFLGLDLDAQQARVGQWLLLFLGIALLVATLGLSQRLFSIRHRSLHRHSHGPQFGSEVELRHS", "length": 1306, "reference_go_mf": ["GO:0003779", "GO:0031711", "GO:0031404", "GO:0004175", "GO:0008238", "GO:0004181", "GO:0070573", "GO:0004222", "GO:0008237", "GO:0051019", "GO:0031434", "GO:0008233", "GO:0008241", "GO:0008240", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_171_1m4l_assembly1", "enzyme_name": "carboxypeptidase A", "ec": ["3.4.17.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00730", "alignment_score": 608.0, "observed_coverage": 1.0, "aligned_identity": 0.993485342019544, "canonical_span": [110, 417], "sequence": "MQGLLILSVLLGAALGKEDFVGHQVLRITAADEAEVQTVKELEDLEHLQLDFWRGPGQPGSPIDVRVPFPSLQAVKVFLEAHGIRYRIMIEDVQSLLDEEQEQMFASQSRARSTNTFNYATYHTLDEIYDFMDLLVAEHPQLVSKLQIGRSYEGRPIYVLKFSTGGSNRPAIWIDLGIHSREWITQATGVWFAKKFTEDYGQDPSFTAILDSMDIFLEIVTNPDGFAFTHSQNRLWRKTRSVTSSSLCVGVDANRNWDAGFGKAGASSSPCSETYHGKYANSEVEVKSIVDFVKDHGNFKAFLSIHSYSQLLLYPYGYTTQSIPDKTELNQVAKSAVEALKSLYGTSYKYGSIITTIYQASGGSIDWSYNQGIKYSFTFELRDTGRYGFLLPASQIIPTAQETWLGVLTIMEHTLNNLY", "length": 419, "reference_go_mf": ["GO:0004181", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_839bdd6d36bcfbefd0f6"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_173_1pq5_assembly1", "enzyme_name": "trypsin", "ec": ["3.4.21.4"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P35049", "alignment_score": 448.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [24, 248], "sequence": "MVKFASVVALVAPLAAAAPQEIPNIVGGTSASAGDFPFIVSISRNGGPWCGGSLLNANTVLTAAHCVSGYAQSGFQIRAGSLSRTSGGITSSLSSVRVHPSYSGNNNDLAILKLSTSIPSGGNIGYARLAASGSDPVAGSSATVAGWGATSEGGSSTPVNLLKVTVPIVSRATCRAQYGTSAITNQMFCAGVSSGGKDSCQGDSGGPIVDSSNTLIGAVSWGNGCARPNYSGVYASVGALRSFIDTYA", "length": 248, "reference_go_mf": ["GO:0004252"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_155ad689b2b45d885db7"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_175_1a30_assembly1", "enzyme_name": "HIV-1 retropepsin", "ec": ["3.4.23.16"], "controls": [{"chain": "A", "status": "reference_overlength", "selected": {"accession": "P04585", "alignment_score": 186.0, "observed_coverage": 1.0, "aligned_identity": 0.9595959595959596, "canonical_span": [488, 587], "sequence": "MGARASVLSGGELDRWEKIRLRPGGKKKYKLKHIVWASRELERFAVNPGLLETSEGCRQILGQLQPSLQTGSEELRSLYNTVATLYCVHQRIEIKDTKEALDKIEEEQNKSKKKAQQAAADTGHSNQVSQNYPIVQNIQGQMVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRVHPVHAGPIAPGQMREPRGSDIAGTTSTLQEQIGWMTNNPPIPVGEIYKRWIILGLNKIVRMYSPTSILDIRQGPKEPFRDYVDRFYKTLRAEQASQEVKNWMTETLLVQNANPDCKTILKALGPAATLEEMMTACQGVGGPGHKARVLAEAMSQVTNSATIMMQRGNFRNQRKIVKCFNCGKEGHTARNCRAPRKKGCWKCGKEGHQMKDCTERQANFLREDLAFLQGKAREFSSEQTRANSPTRRELQVWGRDNNSPSEAGADRQGTVSFNFPQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNFPISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNRGRQKVVTLTDTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDQSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSAGIRKVLFLDGIDKAQDEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTIHTDNGSNFTGATVRAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRNPLWKGPAKLLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVASRQDED", "length": 1435, "reference_go_mf": ["GO:0004190", "GO:0003677", "GO:0003887", "GO:0004533", "GO:0042802", "GO:0008907", "GO:0008289", "GO:0008233", "GO:0003723", "GO:0003964", "GO:0004523", "GO:0005198", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}, {"chain": "B", "status": "reference_overlength", "selected": {"accession": "P04585", "alignment_score": 186.0, "observed_coverage": 1.0, "aligned_identity": 0.9595959595959596, "canonical_span": [488, 587], "sequence": "MGARASVLSGGELDRWEKIRLRPGGKKKYKLKHIVWASRELERFAVNPGLLETSEGCRQILGQLQPSLQTGSEELRSLYNTVATLYCVHQRIEIKDTKEALDKIEEEQNKSKKKAQQAAADTGHSNQVSQNYPIVQNIQGQMVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRVHPVHAGPIAPGQMREPRGSDIAGTTSTLQEQIGWMTNNPPIPVGEIYKRWIILGLNKIVRMYSPTSILDIRQGPKEPFRDYVDRFYKTLRAEQASQEVKNWMTETLLVQNANPDCKTILKALGPAATLEEMMTACQGVGGPGHKARVLAEAMSQVTNSATIMMQRGNFRNQRKIVKCFNCGKEGHTARNCRAPRKKGCWKCGKEGHQMKDCTERQANFLREDLAFLQGKAREFSSEQTRANSPTRRELQVWGRDNNSPSEAGADRQGTVSFNFPQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNFPISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNRGRQKVVTLTDTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDQSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSAGIRKVLFLDGIDKAQDEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTIHTDNGSNFTGATVRAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRNPLWKGPAKLLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVASRQDED", "length": 1435, "reference_go_mf": ["GO:0004190", "GO:0003677", "GO:0003887", "GO:0004533", "GO:0042802", "GO:0008907", "GO:0008289", "GO:0008233", "GO:0003723", "GO:0003964", "GO:0004523", "GO:0005198", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_176_1kei_assembly1", "enzyme_name": "thermolysin", "ec": ["3.4.24.27"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00800", "alignment_score": 632.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [232, 548], "sequence": "MKMKMKLASFGLAAGLAAQVFLPYNALASTEHVTWNQQFQTPQFISGDLLKVNGTSPEELVYQYVEKNENKFKFHENAKDTLQLKEKKNDNLGFTFMRFQQTYKGIPVFGAVVTSHVKDGTLTALSGTLIPNLDTKGSLKSGKKLSEKQARDIAEKDLVANVTKEVPEYEQGKDTEFVVYVNGDEASLAYVVNLNFLTPEPGNWLYIIDAVDGKILNKFNQLDAAKPGDVKSITGTSTVGVGRGVLGDQKNINTTYSTYYYLQDNTRGNGIFTYDAKYRTTLPGSLWADADNQFFASYDAPAVDAHYYAGVTYDYYKNVHNRLSYDGNNAAIRSSVHYSQGYNNAFWNGSQMVYGDGDGQTFIPLSGGIDVVAHELTHAVTDYTAGLIYQNESGAINEAISDIFGTLVEFYANKNPDWEIGEDVYTPGISGDSLRSMSDPAKYGDPDHYSKRYTGTQDNGGVHINSGIINKAAYLISQGGTHYGVSVVGIGRDKLGKIFYRALTQYLTPTSNFSQLRAAAVQSATDLYGSTSQEVASVKQAFDAVGVK", "length": 548, "reference_go_mf": ["GO:0004222"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_757d7de3752b99f00aa2"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_177_1ryp_assembly1", "enzyme_name": "proteasome endopeptidase complex", "ec": ["3.4.25.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P25043", "alignment_score": 444.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [29, 251], "sequence": "MAGLSFDNYQRNNFLAENSHTQPKATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIGSNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPTGSHLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCVMEIGKDAEYLRNYLTPNVREEKQKSYKFPRGTTAVLKESIVNICDIQEEQVDITA", "length": 261, "reference_go_mf": ["GO:0004175", "GO:0004298"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_24b1b0509b3557e01052"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_178_1bmf_assembly1", "enzyme_name": "H+-transporting two-sector ATPase (F-type, mitochondrial)", "ec": ["7.1.2.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P19483", "alignment_score": 981.0, "observed_coverage": 1.0, "aligned_identity": 0.9979674796747967, "canonical_span": [61, 553], "sequence": "MLSVRVAAAVARALPRRAGLVSKNALGSSFIAARNLHASNSRLQKTGTAEVSSILEERILGADTSVDLEETGRVLSIGDGIARVHGLRNVQAEEMVEFSSGLKGMSLNLEPDNVGVVVFGNDKLIKEGDIVKRTGAIVDVPVGEELLGRVVDALGNAIDGKGPIGSKARRRVGLKAPGIIPRISVREPMQTGIKAVDSLVPIGRGQRELIIGDRQTGKTSIAIDTIINQKRFNDGTDEKKKLYCIYVAIGQKRSTVAQLVKRLTDADAMKYTIVVSATASDAAPLQYLAPYSGCSMGEYFRDNGKHALIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDAFGGGSLTALPVIETQAGDVSAYIPTNVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQTRAMKQVAGTMKLELAQYREVAAFAQFGSDLDAATQQLLSRGVRLTELLKQGQYSPMAIEEQVAVIYAGVRGYLDKLEPSKITKFENAFLSHVISQHQALLSKIRTDGKISEESDAKLKEIVTNFLAGFEA", "length": 553, "reference_go_mf": ["GO:0043531", "GO:0005524", "GO:0046933"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_8bce4d8042ad3b18c4de"}, "alternative_alignments": [{"accession": "P00829", "alignment_score": 15.0, "observed_coverage": 0.04878048780487805, "aligned_identity": 0.5416666666666666, "canonical_span": [134, 158], "length": 528, "reference_go_mf": ["GO:0005524", "GO:0016887", "GO:0046933"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, {"accession": "P05631", "alignment_score": 8.0, "observed_coverage": 0.008130081300813009, "aligned_identity": 1.0, "canonical_span": [91, 95], "length": 298, "reference_go_mf": ["GO:0046933"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, {"accession": "P01096", "alignment_score": 8.0, "observed_coverage": 0.008130081300813009, "aligned_identity": 1.0, "canonical_span": [51, 55], "length": 109, "reference_go_mf": ["GO:0043532", "GO:0051117", "GO:0042030", "GO:0005516", "GO:0042802", "GO:0042803", "GO:0005198"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}, {"chain": "B", "status": "assigned", "selected": {"accession": "P00829", "alignment_score": 934.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [58, 525], "sequence": "MLGLVGRVVAASASGALRGLSPSAPLPQAQLLLRAAPAALQPARDYAAQASPSPKAGATTGRIVAVIGAVVDVQFDEGLPPILNALEVQGRETRLVLEVAQHLGESTVRTIAMDGTEGLVRGQKVLDSGAPIRIPVGPETLGRIMNVIGEPIDERGPIKTKQFAAIHAEAPEFVEMSVEQEILVTGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIESGVINLKDATSKVALVYGQMNEPPGARARVALTGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGTMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRAIAELGIYPAVDPLDSTSRIMDPNIVGSEHYDVARGVQKILQDYKSLQDIIAILGMDELSEEDKLTVSRARKIQRFLSQPFQVAEVFTGHLGKLVPLKETIKGFQQILAGEYDHLPEQAFYMVGPIEEAVAKADKLAEEHS", "length": 528, "reference_go_mf": ["GO:0005524", "GO:0016887", "GO:0046933"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_87a89d3c6b1360fab099"}, "alternative_alignments": [{"accession": "P19483", "alignment_score": 15.0, "observed_coverage": 0.05139186295503212, "aligned_identity": 0.5416666666666666, "canonical_span": [140, 164], "length": 553, "reference_go_mf": ["GO:0043531", "GO:0005524", "GO:0046933"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, {"accession": "P05631", "alignment_score": 8.0, "observed_coverage": 0.008565310492505354, "aligned_identity": 1.0, "canonical_span": [179, 183], "length": 298, "reference_go_mf": ["GO:0046933"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, {"accession": "P01096", "alignment_score": 7.0, "observed_coverage": 0.010706638115631691, "aligned_identity": 0.8, "canonical_span": [37, 42], "length": 109, "reference_go_mf": ["GO:0043532", "GO:0051117", "GO:0042030", "GO:0005516", "GO:0042802", "GO:0042803", "GO:0005198"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_179_1q3s_assembly1", "enzyme_name": "chaperonin ATPase", "ec": ["5.6.1.7"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P61112", "alignment_score": 1031.0, "observed_coverage": 1.0, "aligned_identity": 0.9980657640232108, "canonical_span": [9, 526], "sequence": "MAQLSGQPVVILPEGTQRYVGRDAQRLNILAARIIAETVRTTLGPKGMDKMLVDSLGDIVVTNDGATILDKIDLQHPAAKMMVEVAKTQDKEAGDGTTTAVVIAGELLRKAEELLDQNIHPSIIIKGYALAAEKAQEILDEIAIRVDPDDEETLLKIAATSITGKNAESHKELLAKLAVEAVKQVAEKKDGKYVVDLDNIKFEKKAGEGVEESELVRGVVIDKEVVHPRMPKRVENAKIALINEALEVKKTETDAKINITSPDQLMSFLEQEEKMLKDMVDHIAQTGANVVFVQKGIDDLAQHYLAKYGIMAVRRVKKSDMEKLAKATGAKIVTNVKDLTPEDLGYAEVVEERKLAGENMIFVEGCKNPKAVTILIRGGTEHVIDEVERALEDAVKVVKDVMEDGAVLPAGGAPEIELAIRLDEYAKQVGGKEALAIENFADALKIIPKTLAENAGLDTVEMLVKVISEHKNRGLGIGIDVFEGKPADMLEKGIIEPLRVKKQAIKSASEAAIMILRIDDVIAAKATKPEGGQGGGMPGGMGGMDMGM", "length": 548, "reference_go_mf": ["GO:0005524", "GO:0016887", "GO:0140662"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_9418e0c6880dcb414cb9"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_17_1rr6_assembly1", "enzyme_name": "purine-nucleoside phosphorylase", "ec": ["2.4.2.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00491", "alignment_score": 561.0, "observed_coverage": 1.0, "aligned_identity": 0.9964539007092199, "canonical_span": [2, 284], "sequence": "MENGYTYEDYKNTAEWLLSHTKHRPQVAIICGSGLGGLTDKLTQAQIFDYGEIPNFPRSTVPGHAGRLVFGFLNGRACVMMQGRFHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQMGEQRELQEGTYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVIMDYESLEKANHEEVLAAGKQAAQKLEQFVSILMASIPLPDKAS", "length": 289, "reference_go_mf": ["GO:0047975", "GO:0042802", "GO:0001882", "GO:0042301", "GO:0002060", "GO:0004731"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_26869a7fa856d719c193"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_180_1hyo_assembly1", "enzyme_name": "fumarylacetoacetase", "ec": ["3.7.1.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P35505", "alignment_score": 829.0, "observed_coverage": 1.0, "aligned_identity": 0.9975961538461539, "canonical_span": [0, 416], "sequence": "MSFIPVAEDSDFPIQNLPYGVFSTQSNPKPRIGVAIGDQILDLSVIKHLFTGPALSKHQHVFDETTLNNFMGLGQAAWKEARASLQNLLSASQARLRDDKELRQRAFTSQASATMHLPATIGDYTDFYSSRQHATNVGIMFRGKENALLPNWLHLPVGYHGRASSIVVSGTPIRRPMGQMRPDNSKPPVYGACRLLDMELEMAFFVGPGNRFGEPIPISKAHEHIFGMVLMNDWSARDIQQWEYVPLGPFLGKSFGTTISPWVVPMDALMPFVVPNPKQDPKPLPYLCHSQPYTFDINLSVSLKGEGMSQAATICRSNFKHMYWTMLQQLTHHSVNGCNLRPGDLLASGTISGSDPESFGSMLELSWKGTKAIDVEQGQTRTFLLDGDEVIITGHCQGDGYRVGFGQCAGKVLPALSPA", "length": 419, "reference_go_mf": ["GO:0004334"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_443ca3955edaea110f92"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_181_1rql_assembly1", "enzyme_name": "phosphonoacetaldehyde hydrolase", "ec": ["3.11.1.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "O31156", "alignment_score": 511.0, "observed_coverage": 1.0, "aligned_identity": 0.9961089494163424, "canonical_span": [1, 258], "sequence": "MKIEAVIFDWAGTTVDYGCFAPLEVFMEIFHKRGVAITAEEARKPMGLLKIDHVRALTEMPRIASEWNRVFRQLPTEADIQEMYEEFEEILFAILPRYASPINGVKEVIASLRERGIKIGSTTGYTREMMDIVAKEAALQGYKPDFLVTPDDVPAGRPYPWMCYKNAMELGVYPMNHMIKVGDTVSDMKEGRNAGMWTVGVILGSSELGLTEEEVENMDSVELREKIEVVRNRFVENGAHFTIETMQELESVMEHIEKQELIIS", "length": 264, "reference_go_mf": ["GO:0000287", "GO:0008967", "GO:0050194"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_45c1098815afbd9c8d76"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_182_1mum_assembly1", "enzyme_name": "methylisocitrate lyase", "ec": ["4.1.3.30"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P77541", "alignment_score": 578.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [2, 291], "sequence": "MSLHSPGKAFRAALTKENPLQIVGTINANHALLAQRAGYQAIYLSGGGVAAGSLGLPDLGISTLDDVLTDIRRITDVCSLPLLVDADIGFGSSAFNVARTVKSMIKAGAAGLHIEDQVGAKRCGHRPNKAIVSKEEMVDRIRAAVDAKTDPDFVIMARTDALAVEGLDAAIERAQAYVEAGAEMLFPEAITELAMYRQFADAVQVPILANITEFGATPLFTTDELRSAHVAMALYPLSAFRAMNRAAEHVYNVLRQEGTQKSVIDTMQTRNELYESINYYQYEEKLDNLFARSQVK", "length": 296, "reference_go_mf": ["GO:0000287", "GO:0046421"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_50988d44e95641f3fb87"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_183_1dnp_assembly1", "enzyme_name": "deoxyribodipyrimidine photo-lyase", "ec": ["4.1.99.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00914", "alignment_score": 938.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 470], "sequence": "MTTHLVWFRQDLRLHDNLALAAACRNSSARVLALYIATPRQWATHNMSPRQAELINAQLNGLQIALAEKGIPLLFREVDDFVASVEIVKQVCAENSVTHLFYNYQYEVNERARDVEVERALRNVVCEGFDDSVILPPGAVMTGNHEMYKVFTPFKNAWLKRLREGMPECVAAPKVRSSGSIEPSPSITLNYPRQSFDTAHFPVEEKAAIAQLRQFCQNGAGEYEQQRDFPAVEGTSRLSASLATGGLSPRQCLHRLLAEQPQALDGGAGSVWLNELIWREFYRHLITYHPSLCKHRPFIAWTDRVQWQSNPAHLQAWQEGKTGYPIVDAAMRQLNSTGWMHNRLRMITASFLVKDLLIDWREGERYFMSQLIDGDLAANNGGWQWAASTGTDAAPYFRIFNPTTQGEKFDHEGEFIRQWLPELRDVPGKVVHEPWKWAQKAGVTLDYPQPIVEHKEARVQTLAAYEAARKGK", "length": 472, "reference_go_mf": ["GO:0003684", "GO:0003904"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_92f1a32db6b58742950b"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_186_1pwh_assembly1", "enzyme_name": "L-serine ammonia-lyase", "ec": ["4.3.1.17"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P09367", "alignment_score": 627.5, "observed_coverage": 1.0, "aligned_identity": 0.9969418960244648, "canonical_span": [0, 363], "sequence": "MAAQESLHVKTPLRDSMALSKVAGTSVFLKMDSSQPSGSFKIRGIGHLCKMKAKQGCKHFVCSSVVQIWGSRMRGRSHSGDEQPHVRSQALLPDTPSPLTAGNAGMATAYAARRLGLPATIVVPSTTPALTIERLKNEGATVEVVGEMLDEAIQLAKALEKNNPGWVYISPFDDPLIWEGHTSLVKELKETLSAKPGAIVLSVGGGGLLCGVVQGLREVGWEDVPIIAMETFGAHSFHAAVKEGKLVTLPKITSVAKALGVNTVGAQTLKLFYEHPIFSEVISDQEAVTAIEKFVDDEKILVEPACGAALAAVYSGVVCRLQAEGRLQTPLASLVVIVCGGSNISLAQLQALKAQLGLNELLK", "length": 363, "reference_go_mf": ["GO:0003941", "GO:0042803", "GO:0030170", "GO:0004794"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_992ea70b163f023a55cf"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_187_1mns_assembly1", "enzyme_name": "mandelate racemase", "ec": ["5.1.2.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P11444", "alignment_score": 714.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [2, 359], "sequence": "MSEVLITGLRTRAVNVPLAYPVHTAVGTVGTAPLVLIDLATSAGVVGHSYLFAYTPVALKSLKQLLDDMAAMIVNEPLAPVSLEAMLAKRFCLAGYTGLIRMAAAGIDMAAWDALGKVHETPLVKLLGANARPVQAYDSHSLDGVKLATERAVTAAELGFRAVKTKIGYPALDQDLAVVRSIRQAVGDDFGIMVDYNQSLDVPAAIKRSQALQQEGVTWIEEPTLQHDYEGHQRIQSKLNVPVQMGENWLGPEEMFKALSIGACRLAMPDAMKIGGVTGWIRASALAQQFGIPMSSHLFQEISAHLLAATPTAHWLERLDLAGSVIEPTLTFEGGNAVIPDLPGVGIIWREKEIGKYLV", "length": 359, "reference_go_mf": ["GO:0016836", "GO:0000287", "GO:0018838"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_9d501977be07ee48cb2c"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_188_1xel_assembly1", "enzyme_name": "UDP-glucose 4-epimerase", "ec": ["5.1.3.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P09147", "alignment_score": 673.0, "observed_coverage": 1.0, "aligned_identity": 0.9970414201183432, "canonical_span": [0, 338], "sequence": "MRVLVTGGSGYIGSHTCVQLLQNGHDVIILDNLCNSKRSVLPVIERLGGKHPTFVEGDIRNEALMTEILHDHAIDTVIHFAGLKAVGESVQKPLEYYDNNVNGTLRLISAMRAANVKNFIFSSSATVYGDQPKIPYVESFPTGTPQSPYGKSKLMVEQILTDLQKAQPDWSIALLRYFNPVGAHPSGDMGEDPQGIPNNLMPYIAQVAVGRRDSLAIFGNDYPTEDGTGVRDYIHVMDLADGHVVAMEKLANKPGVHIYNLGAGVGNSVLDVVNAFSKACGKPVNYHFAPRREGDLPAYWADASKADRELNWRVTRTLDEMAQDTWHWQSRHPQGYPD", "length": 338, "reference_go_mf": ["GO:0042802", "GO:0070403", "GO:0016857", "GO:0003978"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_4369495df3d7617c874a"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_189_1m9c_assembly1", "enzyme_name": "peptidylprolyl isomerase (cyclophilin-type)", "ec": ["5.2.1.8"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P62937", "alignment_score": 330.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 165], "sequence": "MVNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQLE", "length": 165, "reference_go_mf": ["GO:0016018", "GO:1904399", "GO:0005178", "GO:0003755", "GO:0003723", "GO:0046790"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_71376b3a50a1cc063e09"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_18_1jdw_assembly1", "enzyme_name": "glycine amidinotransferase", "ec": ["2.1.4.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P50440", "alignment_score": 720.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [63, 423], "sequence": "MLRVRCLRGGSRGAEAVHYIGSRLGRTLTGWVQRTFQSTQAATASSRNSCAADDKATEPLPKDCPVSSYNEWDPLEEVIVGRAENACVPPFTIEVKANTYEKYWPFYQKQGGHYFPKDHLKKAVAEIEEMCNILKTEGVTVRRPDPIDWSLKYKTPDFESTGLYSAMPRDILIVVGNEIIEAPMAWRSRFFEYRAYRSIIKDYFHRGAKWTTAPKPTMADELYNQDYPIHSVEDRHKLAAQGKFVTTEFEPCFDAADFIRAGRDIFAQRSQVTNYLGIEWMRRHLAPDYRVHIISFKDPNPMHIDATFNIIGPGIVLSNPDRPCHQIDLFKKAGWTIITPPTPIIPDDHPLWMSSKWLSMNVLMLDEKRVMVDANEVPIQKMFEKLGITTIKVNIRNANSLGGGFHCWTCDVRRRGTLQSYLD", "length": 423, "reference_go_mf": ["GO:0015067", "GO:0015068"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_6d128a2a109e3774b4b6"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_190_1nfs_assembly1", "enzyme_name": "isopentenyl-diphosphate delta-isomerase (type 1)", "ec": ["5.3.3.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q46822", "alignment_score": 352.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [3, 179], "sequence": "MQTEHVILLNAQGVPTGTLEKYAAHTADTRLHLAFSSWLFNAKGQLLVTRRALSKKAWPGVWTNSVCGHPQLGESNEDAVIRRCRYELGVEITPPESIYPDFRYRATDPSGIVENEVCPVFAARTTSALQINDDEVMDYQWCDLADVLHGIDATPWAFSPWMVMQATNREARKRLSAFTQLK", "length": 182, "reference_go_mf": ["GO:0004452", "GO:0000287", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_d7900d084d532690602b"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_191_1mek_assembly1", "enzyme_name": "protein disulfide-isomerase (eukaryotic)", "ec": ["5.3.4.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P07237", "alignment_score": 240.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [17, 137], "sequence": "MLRRALLCLAVAALVRADAPEEEDHVLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGREADDIVNWLKKRTGPAATTLPDGAAAESLVESSEVAVIGFFKDVESDSAKQFLQAAEAIDDIPFGITSNSDVFSKYQLDKDGVVLFKKFDEGRNNFEGEVTKENLLDFIKHNQLPLVIEFTEQTAPKIFGGEIKTHILLFLPKSVSDYDGKLSNFKTAAESFKGKILFIFIDSDHTDNQRILEFFGLKKEECPAVRLITLEEEMTKYKPESEELTAERITEFCHRFLEGKIKPHLMSQELPEDWDKQPVKVLVGKNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDSTANEVEAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKFLESGGQDGAGDDDDLEDLEEAEEPDMEEDDDQKAVKDEL", "length": 508, "reference_go_mf": ["GO:0003779", "GO:0019899", "GO:0005178", "GO:0004656", "GO:0003756", "GO:0046982", "GO:0015035", "GO:0003723", "GO:0016972"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_f7378b5dc0b49c20b4c8"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_192_1z9h_assembly1", "enzyme_name": "prostaglandin-E synthase", "ec": ["5.3.99.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q9N0A4", "alignment_score": 548.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [99, 373], "sequence": "MAPATRVVRALWTGGCALAWRLGGRPQPLLPTQSRAGFAGAAGGQGPVAAARKGSPRLLGAAALALGGALGLYHTARWHLHAQDLHAERSAVQLSLSSRLQLTLYQYKTCPFCSKVRAFLDFHALPYQVVEVNPVLRAEIKFSSYRKVPILVAQEGESSQQLNDSSVIISALKTYLVSGQPLEEIITYYPAMKAVNDQGKEVTEFGNKYWLMLNEKEAQQVYSGKEARTEEMKWRQWADDWLVHLISPNVYRTPTEALASFDYIVREGKFGAVEGAVAKYMGAAAMYLISKRLKSRHRLQDNVREDLYEAADKWVAAVGKDRPFMGGQKPNLADLAVYGVLRVMEGLDAFDDLMQHTHIQPWYLRVERAITEASPAH", "length": 377, "reference_go_mf": ["GO:0036134", "GO:0043295", "GO:0020037", "GO:0042802", "GO:0016829", "GO:0050220"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_0ed4dc70a47eab506a31"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_195_2gsa_assembly1", "enzyme_name": "glutamate-1-semialdehyde 2,1-aminomutase", "ec": ["5.4.3.8"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P24630", "alignment_score": 839.0, "observed_coverage": 1.0, "aligned_identity": 0.9882903981264637, "canonical_span": [6, 433], "sequence": "MVTSSPFKTIKSDEIFAAAQKLMPGGVSSPVRAFKSVGGQPIVFDRVKDAYAWDVDGNRYIDYVGTWGPAICGHAHPEVIEALKVAMEKGTSFGAPCALENVLAEMVIDAVPSIEMVRFVNSGTEACMAVLRLMRAYTGRDKIIKFEGCYHGHADMFLVKAGSGVATLGLPDSPGVPKSTTANTLTAPYNDLEAVKALFAENPGEIAGVILEPIVGNSGFIVPDAGFLEGLREITLEHDALLVFDEVMTGFRIAYGGVQEKFGVTPDLTTLGKIIGGGLPVGAYGGKREIMQLVAPAGPMYQAGTLSGNPLAMTAGIKTLELLRQPATYEYLDQITKRLSDGLLAIAQETGHAACGGQVSGMFGFFFTEGPVHNYEDAKKSDLQKFSRFHRGMLEQGIYLAPSQFEAGFTSLAHTEEDIDATLAAARTVMSAL", "length": 433, "reference_go_mf": ["GO:0042286", "GO:0030170"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_656771ab6e217d7eb3fa"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_196_1eyq_assembly1", "enzyme_name": "chalcone isomerase", "ec": ["5.5.1.6"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P28012", "alignment_score": 424.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [3, 215], "sequence": "MAASITAITVENLEYPAVVTSPVTGKSYFLGGAGERGLTIEGNFIKFTAIGVYLEDIAVASLAAKWKGKSSEELLETLDFYRDIISGPFEKLIRGSKIRELSGPEYSRKVMENCVAHLKSVGTYGDAEAEAMQKFAEAFKPVNFPPGASVFYRQSPDGILGLSFSPDTSIPEKEAALIENKAVSSAVLETMIGEHAVSPDLKRCLAARLPALLNEGAFKIGN", "length": 222, "reference_go_mf": ["GO:0045430"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_31dc7f13cafc0038ea17"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_197_2ts1_assembly1", "enzyme_name": "tyrosine-tRNA ligase", "ec": ["6.1.1.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00952", "alignment_score": 627.5, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 319], "sequence": "MDLLAELQWRGLVNQTTDEDGLRKLLNEERVTLYCGFDPTADSLHIGHLATILTMRRFQQAGHRPIALVGGATGLIGDPSGKKSERTLNAKETVEAWSARIKEQLGRFLDFEADGNPAKIKNNYDWIGPLDVITFLRDVGKHFSVNYMMAKESVQSRIETGISFTEFSYMMLQAYDFLRLYETEGCRLQIGGSDQWGNITAGLELIRKTKGEARAFGLTIPLVTKADGTKFGKTESGTIWLDKEKTSPYEFYQFWINTDDRDVIRYLKYFTFLSKEEIEALEQELREAPEKRAAQKTLAEEVTKLVHGEEALRQAIRISEALFSGDIANLTAAEIEQGFKDVPSFVHEGGDVPLVELLVSAGISPSKRQAREDIQNGAIYVNGERLQDVGAILTAEHRLEGRFTVIRRGKKKYYLIRYA", "length": 419, "reference_go_mf": ["GO:0005524", "GO:0042803", "GO:0000049", "GO:0004831"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_30d4843c25e22ef30236"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_198_1v25_assembly1", "enzyme_name": "long-chain-fatty-acid-CoA ligase", "ec": ["6.2.1.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q5SKN9", "alignment_score": 944.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [7, 541], "sequence": "MEGERMNAFPSTMMDEELNLWDFLERAAALFGRKEVVSRLHTGEVHRTTYAEVYQRARRLMGGLRALGVGVGDRVATLGFNHFRHLEAYFAVPGMGAVLHTANPRLSPKEIAYILNHAEDKVLLFDPNLLPLVEAIRGELKTVQHFVVMDEKAPEGYLAYEEALGEEADPVRVPERAACGMAYTTGTTGLPKGVVYSHRALVLHSLAASLVDGTALSEKDVVLPVVPMFHVNAWCLPYAATLVGAKQVLPGPRLDPASLVELFDGEGVTFTAGVPTVWLALADYLESTGHRLKTLRRLVVGGSAAPRSLIARFERMGVEVRQGYGLTETSPVVVQNFVKSHLESLSEEEKLTLKAKTGLPIPLVRLRVADEEGRPVPKDGKALGEVQLKGPWITGGYYGNEEATRSALTPDGFFRTGDIAVWDEEGYVEIKDRLKDLIKSGGEWISSVDLENALMGHPKVKEAAVVAIPHPKWQERPLAVVVPRGEKPTPEELNEHLLKAGFAKWQLPDAYVFAEEIPRTSAGKFLKRALREQYKNYYGGA", "length": 541, "reference_go_mf": ["GO:0005524", "GO:0042802", "GO:0004467", "GO:0000287", "GO:0042803"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_462459aa463034240071"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_199_1gsa_assembly2", "enzyme_name": "glutathione synthase (prokaryotic)", "ec": ["6.3.2.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P04425", "alignment_score": 628.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 314], "sequence": "MIKLGIVMDPIANINIKKDSSFAMLLEAQRRGYELHYMEMGDLYLINGEARAHTRTLNVKQNYEEWFSFVGEQDLPLADLDVILMRKDPPFDTEFIYATYILERAEEKGTLIVNKPQSLRDCNEKLFTAWFSDLTPETLVTRNKAQLKAFWEKHSDIILKPLDGMGGASIFRVKEGDPNLGVIAETLTEHGTRYCMAQNYLPAIKDGDKRVLVVDGEPVPYCLARIPQGGETRGNLAAGGRGEPRPLTESDWKIARQIGPTLKEKGLIFVGLDIIGDRLTEINVTSPTCIREIEAEFPVSITGMLMDAIEARLQQQ", "length": 316, "reference_go_mf": ["GO:0005524", "GO:0004363", "GO:0042802", "GO:0000287"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_2fd7df97dbc332c14539"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_1_1b73_assembly1", "enzyme_name": "glutamate racemase", "ec": ["5.1.1.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P56868", "alignment_score": 498.0, "observed_coverage": 1.0, "aligned_identity": 0.9920634920634921, "canonical_span": [0, 252], "sequence": "MKIGIFDSGVGGLTVLKAIRNRYRKVDIVYLGDTARVPYGIRSKDTIIRYSLECAGFLKDKGVDIIVVACNTASAYALERLKKEINVPVFGVIEPGVKEALKKSRNKKIGVIGTPATVKSGAYQRKLEEGGADVFAKACPLFVPLAEEGLLEGEITRKVVEHYLKEFKGKIDTLILGCTHYPLLKKEIKKFLGDVEVVDSSEALSLSLHNFIKDDGSSSLELFFTDLSPNLQFLIKLILGRDYPVKLAEGVFTH", "length": 254, "reference_go_mf": ["GO:0008881"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_d9550fb556eca48264ad"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P56868", "alignment_score": 498.0, "observed_coverage": 1.0, "aligned_identity": 0.9920634920634921, "canonical_span": [0, 252], "sequence": "MKIGIFDSGVGGLTVLKAIRNRYRKVDIVYLGDTARVPYGIRSKDTIIRYSLECAGFLKDKGVDIIVVACNTASAYALERLKKEINVPVFGVIEPGVKEALKKSRNKKIGVIGTPATVKSGAYQRKLEEGGADVFAKACPLFVPLAEEGLLEGEITRKVVEHYLKEFKGKIDTLILGCTHYPLLKKEIKKFLGDVEVVDSSEALSLSLHNFIKDDGSSSLELFFTDLSPNLQFLIKLILGRDYPVKLAEGVFTH", "length": 254, "reference_go_mf": ["GO:0008881"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_d9550fb556eca48264ad"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_201_1xny_assembly1", "enzyme_name": "propionyl-CoA carboxylase", "ec": ["6.4.1.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q9X4K7", "alignment_score": 1042.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [9, 530], "sequence": "MSEPEEQQPDIHTTAGKLADLRRRIEEATHAGSARAVEKQHAKGKLTARERIDLLLDEGSFVELDEFARHRSTNFGLDANRPYGDGVVTGYGTVDGRPVAVFSQDFTVFGGALGEVYGQKIVKVMDFALKTGCPVVGINDSGGARIQEGVASLGAYGEIFRRNTHASGVIPQISLVVGPCAGGAVYSPAITDFTVMVDQTSHMFITGPDVIKTVTGEDVGFEELGGARTHNSTSGVAHHMAGDEKDAVEYVKQLLSYLPSNNLSEPPAFPEEADLAVTDEDAELDTIVPDSANQPYDMHSVIEHVLDDAEFFETQPLFAPNILTGFGRVEGRPVGIVANQPMQFAGCLDITASEKAARFVRTCDAFNVPVLTFVDVPGFLPGVDQEHDGIIRRGAKLIFAYAEATVPLITVITRKAFGGAYDVMGSKHLGADLNLAWPTAQIAVMGAQGAVNILHRRTIADAGDDAEATRARLIQEYEDALLNPYTAAERGYVDAVIMPSDTRRHIVRGLRQLRTKRESLPPKKHGNIPL", "length": 530, "reference_go_mf": ["GO:0003989", "GO:0004658"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_80a6174b28d740bdfa88"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "Q9X4K7", "alignment_score": 1042.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [9, 530], "sequence": "MSEPEEQQPDIHTTAGKLADLRRRIEEATHAGSARAVEKQHAKGKLTARERIDLLLDEGSFVELDEFARHRSTNFGLDANRPYGDGVVTGYGTVDGRPVAVFSQDFTVFGGALGEVYGQKIVKVMDFALKTGCPVVGINDSGGARIQEGVASLGAYGEIFRRNTHASGVIPQISLVVGPCAGGAVYSPAITDFTVMVDQTSHMFITGPDVIKTVTGEDVGFEELGGARTHNSTSGVAHHMAGDEKDAVEYVKQLLSYLPSNNLSEPPAFPEEADLAVTDEDAELDTIVPDSANQPYDMHSVIEHVLDDAEFFETQPLFAPNILTGFGRVEGRPVGIVANQPMQFAGCLDITASEKAARFVRTCDAFNVPVLTFVDVPGFLPGVDQEHDGIIRRGAKLIFAYAEATVPLITVITRKAFGGAYDVMGSKHLGADLNLAWPTAQIAVMGAQGAVNILHRRTIADAGDDAEATRARLIQEYEDALLNPYTAAERGYVDAVIMPSDTRRHIVRGLRQLRTKRESLPPKKHGNIPL", "length": 530, "reference_go_mf": ["GO:0003989", "GO:0004658"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_80a6174b28d740bdfa88"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_202_1a0i_assembly1", "enzyme_name": "DNA ligase (ATP)", "ec": ["6.5.1.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00969", "alignment_score": 643.0, "observed_coverage": 0.9969879518072289, "aligned_identity": 1.0, "canonical_span": [2, 349], "sequence": "MMNIKTNPFKAVSFVESAIKKALDNAGYLIAEIKYDGVRGNICVDNTANSYWLSRVSKTIPALEHLNGFDVRWKRLLNDDRCFYKDGFMLDGELMVKGVDFNTGSGLLRTKWTDTKNQEFHEELFVEPIRKKDKVPFKLHTGHLHIKLYAILPLHIVESGEDCDVMTLLMQEHVKNMLPLLQEYFPEIEWQAAESYEVYDMVELQQLYEQKRAEGHEGLIVKDPMCIYKRGKKSGWWKMKPENEADGIIQGLVWGTKGLANEGKVIGFEVLLESGRLVNATNISRALMDEFTETVKEATLSQWGFFSPYGIGDNDACTINPYDGWACQISYMEETPDGSLRHPSFVMFRGTEDNPQEKM", "length": 359, "reference_go_mf": ["GO:0005524", "GO:0003910", "GO:0003690", "GO:0046872"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_0efe93247251ba9b4890"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_203_1dpx_assembly1", "enzyme_name": "lysozyme (glycosyl hydrolase 22 family)", "ec": ["3.2.1.17"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00698", "alignment_score": 258.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [18, 147], "sequence": "MRSLLILVLCFLPLAALGKVFGRCELAAAMKRHGLDNYRGYSLGNWVCAAKFESNFNTQATNRNTDGSTDYGILQINSRWWCNDGRTPGSRNLCNIPCSALLSSDITASVNCAKKIVSDGNGMNAWVAWRNRCKGTDVQAWIRGCRL", "length": 147, "reference_go_mf": ["GO:0016231", "GO:0042802", "GO:0003796"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_e30483cd7af62db58cf1"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_205_1gpb_assembly1", "enzyme_name": "Glycogen phosphorylase", "ec": ["2.4.1.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00489", "alignment_score": 1643.0, "observed_coverage": 1.0, "aligned_identity": 0.9987849331713244, "canonical_span": [19, 842], "sequence": "MSRPLSDQEKRKQISVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGRVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPNDFNLKDFNVGGYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTNFDAFPDKVAIQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVLPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKFQNKTNGITPRRWLVLCNPGLAEIIAERIGEEYISDLDQLRKLLSYVDDEAFIRDVAKVKQENKLKFAAYLEREYKVHINPNSLFDVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVDRLDQRGYNAQEYYDRIPELRQIIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYEEYVKCQERVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPAPDEKIP", "length": 843, "reference_go_mf": ["GO:0004645", "GO:0008184", "GO:0030170"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_a4eae8363ad16eea6c94"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_206_1o08_assembly1", "enzyme_name": "beta-phosphoglucomutase", "ec": ["5.4.2.6"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P71447", "alignment_score": 436.0, "observed_coverage": 1.0, "aligned_identity": 0.9909502262443439, "canonical_span": [0, 221], "sequence": "MFKAVLFDLDGVITDTAEYHFRAWKALAEEIGINGVDRQFNEQLKGVSREDSLQKILDLADKKVSAEEFKELAKRKNDNYVKMIQDVSPADVYPGILQLLKDLRSNKIKIALASASKNGPFLLEKMNLTGYFDAIADPAEVAASKPAPDIFIAAAHAVGVAPSESIGLEDSQAGIQAIKDSGALPIGVGRPEDLGDDIVIVPDTSYYTLEFLKEVWLQKQK", "length": 221, "reference_go_mf": ["GO:0008801", "GO:0000287"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_a76484e5b19a83bd0199"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_207_1kc7_assembly1", "enzyme_name": "pyruvate, phosphate dikinase", "ec": ["2.7.9.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P22983", "alignment_score": 1744.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 873], "sequence": "MAKWVYKFEEGNASMRNLLGGKGCNLAEMTILGMPIPQGFTVTTEACTEYYNSGKQITQEIQDQIFEAITWLEELNGKKFGDTEDPLLVSVRSGARASMPGMMDTILNLGLNDVAVEGFAKKTGNPRFAYDSYRRFIQMYSDVVMEVPKSHFEKIIDAMKEEKGVHFDTDLTADDLKELAEKFKAVYKEAMNGEEFPQEPKDQLMGAVKAVFRSWDNPRAIVYRRMNDIPGDWGTAVNVQTMVFGNKGETSGTGVAFTRNPSTGEKGIYGEYLINAQGEDVVAGVRTPQPITQLENDMPDCYKQFMDLAMKLEKHFRDMQDMEFTIEEGKLYFLQTRNGKRTAPAALQIACDLVDEGMITEEEAVVRIEAKSLDQLLHPTFNPAALKAGEVIGSALPASPGAAAGKVYFTADEAKAAHEKGERVILVRLETSPEDIEGMHAAEGILTVRGGMTSHAAVVARGMGTCCVSGCGEIKINEEAKTFELGGHTFAEGDYISLDGSTGKIYKGDIETQEASVSGSFERIMVWADKFRTLKVRTNADTPEDTLNAVKLGAEGIGLCRTEHMFFEADRIMKIRKMILSDSVEAREEALNELIPFQKGDFKAMYKALEGRPMTVRYLDPPLHEFVPHTEEEQAELAKNMGLTLAEVKAKVDELHEFNPMMGHRGCRLAVTYPEIAKMQTRAVMEAAIEVKEETGIDIVPEIMIPLVGEKKELKFVKDVVVEVAEQVKKEKGSDMQYHIGTMIEIPRAALTADAIAEEAEFFSFGTNDLTQMTFGFSRDDAGKFLDSYYKAKIYESDPFARLDQTGVGQLVEMAVKKGRQTRPGLKCGICGEHGGDPSSVEFCHKVGLNYVSCSPFRVPIARLAAAQAALNNK", "length": 874, "reference_go_mf": ["GO:0005524", "GO:0016301", "GO:0050242"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_aaf9b5edfbce6dca595e"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_208_1ezv_assembly1", "enzyme_name": "ubiquinol-cytochrome-c reductase", "ec": ["7.1.1.8"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00163", "alignment_score": 767.0, "observed_coverage": 1.0, "aligned_identity": 0.9974025974025974, "canonical_span": [0, 385], "sequence": "MAFRKSNVYLSLVNSYIIDSPQPSSINYWWNMGSLLGLCLVIQIVTGIFMAMHYSSNIELAFSSVEHIMRDVHNGYILRYLHANGASFFFMVMFMHMAKGLYYGSYRSPRVTLWNVGVIIFILTIATAFLGYCCVYGQMSHWGATVITNLFSAIPFVGNDIVSWLWGGFSVSNPTIQRFFALHYLVPFIIAAMVIMHLMALHIHGSSNPLGITGNLDRIPMHSYFIFKDLVTVFLFMLILALFVFYSPNTLGHPDNYIPGNPLVTPASIVPEWYLLPFYAILRSIPDKLLGVITMFAAILVLLVLPFTDRSVVRGNTFKVLSKFFFFIFVFNFVLLGQIGACHVEVPYVLMGQIATFIYFAYFLIIVPVISTIENVLFYIGRVNK", "length": 385, "reference_go_mf": ["GO:0008121"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_9c3b0ce636aca0d6b836"}, "alternative_alignments": [{"accession": "P07143", "alignment_score": 8.0, "observed_coverage": 0.01818181818181818, "aligned_identity": 0.7142857142857143, "canonical_span": [268, 275], "length": 309, "reference_go_mf": ["GO:0020037", "GO:0008121"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, {"accession": "P08067", "alignment_score": 7.0, "observed_coverage": 0.02077922077922078, "aligned_identity": 0.625, "canonical_span": [57, 65], "length": 215, "reference_go_mf": ["GO:0051537", "GO:0016491", "GO:0008121"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}, {"chain": "B", "status": "assigned", "selected": {"accession": "P08067", "alignment_score": 370.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [30, 215], "sequence": "MLGIRSSVKTCFKPMSLTSKRLISQSLLASKSTYRTPNFDDVLKENNDADKGRSYAYFMVGAMGLLSSAGAKSTVETFISSMTATADVLAMAKVEVNLAAIPLGKNVVVKWQGKPVFIRHRTPHEIQEANSVDMSALKDPQTDADRVKDPQWLIMLGICTHLGCVPIGEAGDFGGWFCPCHGSHYDISGRIRKGPAPLNLEIPAYEFDGDKVIVG", "length": 215, "reference_go_mf": ["GO:0051537", "GO:0016491", "GO:0008121"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_2e025f9620390b344cd4"}, "alternative_alignments": [{"accession": "P00163", "alignment_score": 7.0, "observed_coverage": 0.043243243243243246, "aligned_identity": 0.625, "canonical_span": [93, 101], "length": 385, "reference_go_mf": ["GO:0008121"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, {"accession": "P07143", "alignment_score": 7.0, "observed_coverage": 0.02702702702702703, "aligned_identity": 0.8, "canonical_span": [223, 228], "length": 309, "reference_go_mf": ["GO:0020037", "GO:0008121"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_20_1qjd_assembly1", "enzyme_name": "fumarate reductase (quinol)", "ec": ["1.3.5.4"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q07WU7", "alignment_score": 1136.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [25, 593], "sequence": "MKKMNLAVCIATLMGTAGLMGTAVAADNLAEFHVQNQECDSCHTPDGELSNDSLTYENTQCVSCHGTLAEVAETTKHEHYNAHASHFPGEVACTSCHSAHEKSMVYCDSCHSFDFNMPYAKKWLRDEPTIAELAKDKSERQAALASAPHDTVDVVVVGSGGAGFSAAISATDSGAKVILIEKEPVIGGNAKLAAGGMNAAWTDQQKAKKITDSPELMFEDTMKGGQNINDPALVKVLSSHSKDSVDWMTAMGADLTDVGMMGGASVNRAHRPTGGAGVGAHVVQVLYDNAVKRNIDLRMNTRGIEVLKDDKGTVKGILVKGMYKGYYWVKADAVILATGGFAKNNERVAKLDPSLKGFISTNQPGAVGDGLDVAENAGGALKDMQYIQAHPTLSVKGGVMVTEAVRGNGAILVNREGKRFVNEITTRDKASAAILAQTGKSAYLIFDDSVRKSLSKIDKYIGLGVAPTADSLVKLGKMEGIDGKALTETVARYNSLVSSGKDTDFERPNLPRALNEGNYYAIEVTPGVHHTMGGVMIDTKAEVMNAKKQVIPGLYGAGEVTGGVHGANRLGGNAISDIITFGRLAGEEAAKYSKKN", "length": 596, "reference_go_mf": ["GO:0010181", "GO:0016627"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_389dccabef8ab6815f77"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_211_1idt_assembly1", "enzyme_name": "oxygen insensitive NAD(P)H nitroreductase", "ec": ["1.7.1.16"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P38489", "alignment_score": 434.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 217], "sequence": "MDIISVALKRHSTKAFDASKKLTPEQAEQIKTLLQYSPSSTNSQPWHFIVASTEEGKARVAKSAAGNYVFNERKMLDASHVVVFCAKTAMDDVWLKLVVDQEDADGRFATPEAKAANDKGRKFFADMHRKDLHDDAEWMAKQVYLNVGNFLLGVAALGLDAVPIEGFDAAILDAEFGLKEKGYTSLVVVPVGHHSVEDFNATLPKSRLPQNITLTEV", "length": 217, "reference_go_mf": ["GO:0004155", "GO:0010181", "GO:0042802", "GO:0003955", "GO:0016491", "GO:0042803"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_29f206447ee4cb553476"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_212_1n2c_assembly1", "enzyme_name": "nitrogenase", "ec": ["1.18.6.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P07328", "alignment_score": 956.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [3, 481], "sequence": "MTGMSREEVESLIQEVLEVYPEKARKDRNKHLAVNDPAVTQSKKCIISNKKSQPGLMTIRGCAYAGSKGVVWGPIKDMIHISHGPVGCGQYSRAGRRNYYIGTTGVNAFVTMNFTSDFQEKDIVFGGDKKLAKLIDEVETLFPLNKGISVQSECPIGLIGDDIESVSKVKGAELSKTIVPVRCEGFRGVSQSLGHHIANDAVRDWVLGKRDEDTTFASTPYDVAIIGDYNIGGDAWSSRILLEEMGLRCVAQWSGDGSISEIELTPKVKLNLVHCYRSMNYISRHMEEKYGIPWMEYNFFGPTKTIESLRAIAAKFDESIQKKCEEVIAKYKPEWEAVVAKYRPRLEGKRVMLYIGGLRPRHVIGAYEDLGMEVVGTGYEFAHNDDYDRTMKEMGDSTLLYDDVTGYEFEEFVKRIKPDLIGSGIKEKFIFQKMGIPFREMHSWDYSGPYHGFDGFAIFARDMDMTLNNPCWKKLQAPWEASEGAEKVAASA", "length": 492, "reference_go_mf": ["GO:0051536", "GO:0016163"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_1f3742d53379b781879a"}, "alternative_alignments": [{"accession": "P00459", "alignment_score": 10.0, "observed_coverage": 0.010460251046025104, "aligned_identity": 1.0, "canonical_span": [113, 118], "length": 290, "reference_go_mf": ["GO:0005524", "GO:0016163"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, {"accession": "P07329", "alignment_score": 8.0, "observed_coverage": 0.02092050209205021, "aligned_identity": 0.6, "canonical_span": [59, 69], "length": 523, "reference_go_mf": ["GO:0016163"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}, {"chain": "B", "status": "assigned", "selected": {"accession": "P07329", "alignment_score": 1044.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 523], "sequence": "MSQQVDKIKASYPLFLDQDYKDMLAKKRDGFEEKYPQDKIDEVFQWTTTKEYQELNFQREALTVNPAKACQPLGAVLCALGFEKTMPYVHGSQGCVAYFRSYFNRHFREPVSCVSDSMTEDAAVFGGQQNMKDGLQNCKATYKPDMIAVSTTCMAEVIGDDLNAFINNSKKEGFIPDEFPVPFAHTPSFVGSHVTGWDNMFEGIARYFTLKSMDDKVVGSNKKINIVPGFETYLGNFRVIKRMLSEMGVGYSLLSDPEEVLDTPADGQFRMYAGGTTQEEMKDAPNALNTVLLQPWHLEKTKKFVEGTWKHEVPKLNIPMGLDWTDEFLMKVSEISGQPIPASLTKERGRLVDMMTDSHTWLHGKRFALWGDPDFVMGLVKFLLELGCEPVHILCHNGNKRWKKAVDAILAASPYGKNATVYIGKDLWHLRSLVFTDKPDFMIGNSYGKFIQRDTLHKGKEFEVPLIRIGFPIFDRHHLHRSTTLGYEGAMQILTTLVNSILERLDEETRGMQATDYNHDLVR", "length": 523, "reference_go_mf": ["GO:0016163"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_90d14f01041688fc46b9"}, "alternative_alignments": [{"accession": "P07328", "alignment_score": 8.0, "observed_coverage": 0.007662835249042145, "aligned_identity": 1.0, "canonical_span": [286, 290], "length": 492, "reference_go_mf": ["GO:0051536", "GO:0016163"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, {"accession": "P00459", "alignment_score": 7.0, "observed_coverage": 0.009578544061302681, "aligned_identity": 0.8, "canonical_span": [63, 68], "length": 290, "reference_go_mf": ["GO:0005524", "GO:0016163"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}, {"chain": "C", "status": "assigned", "selected": {"accession": "P00459", "alignment_score": 548.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 275], "sequence": "MAMRQCAIYGKGGIGKSTTTQNLVAALAEMGKKVMIVGCDPKADSTRLILHSKAQNTIMEMAAEAGTVEDLELEDVLKAGYGGVKCVESGGPEPGVGCAGRGVITAINFLEEEGAYEDDLDFVFYDVLGDVVCGGFAMPIRENKAQEIYIVCSGEMMAMYAANNISKGIVKYANSGSVRLGGLICNSRNTDREDELIIALANKLGTQMIHFVPRDNVVQRAEIRRMTVIEYDPKAKQADEYRALARKVVDNKLLVIPNPITMDELEELLMEFGIMEVEDESIVGKTAEEV", "length": 290, "reference_go_mf": ["GO:0005524", "GO:0016163"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_7613e5914ede2261fcbb"}, "alternative_alignments": [{"accession": "P07328", "alignment_score": 10.0, "observed_coverage": 0.01824817518248175, "aligned_identity": 1.0, "canonical_span": [364, 369], "length": 492, "reference_go_mf": ["GO:0051536", "GO:0016163"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, {"accession": "P07329", "alignment_score": 7.0, "observed_coverage": 0.01824817518248175, "aligned_identity": 0.8, "canonical_span": [243, 248], "length": 523, "reference_go_mf": ["GO:0016163"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}, {"chain": "D", "status": "assigned", "selected": {"accession": "P00459", "alignment_score": 548.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 275], "sequence": "MAMRQCAIYGKGGIGKSTTTQNLVAALAEMGKKVMIVGCDPKADSTRLILHSKAQNTIMEMAAEAGTVEDLELEDVLKAGYGGVKCVESGGPEPGVGCAGRGVITAINFLEEEGAYEDDLDFVFYDVLGDVVCGGFAMPIRENKAQEIYIVCSGEMMAMYAANNISKGIVKYANSGSVRLGGLICNSRNTDREDELIIALANKLGTQMIHFVPRDNVVQRAEIRRMTVIEYDPKAKQADEYRALARKVVDNKLLVIPNPITMDELEELLMEFGIMEVEDESIVGKTAEEV", "length": 290, "reference_go_mf": ["GO:0005524", "GO:0016163"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_7613e5914ede2261fcbb"}, "alternative_alignments": [{"accession": "P07328", "alignment_score": 10.0, "observed_coverage": 0.01824817518248175, "aligned_identity": 1.0, "canonical_span": [364, 369], "length": 492, "reference_go_mf": ["GO:0051536", "GO:0016163"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, {"accession": "P07329", "alignment_score": 7.0, "observed_coverage": 0.01824817518248175, "aligned_identity": 0.8, "canonical_span": [243, 248], "length": 523, "reference_go_mf": ["GO:0016163"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_213_1l6g_assembly1", "enzyme_name": "alanine racemase", "ec": ["5.1.1.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P10724", "alignment_score": 756.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 383], "sequence": "MNDFHRDTWAEVDLDAIYDNVENLRRLLPDDTHIMAVVKANAYGHGDVQVARTALEAGASRLAVAFLDEALALREKGIEAPILVLGASRPADAALAAQQRIALTVFRSDWLEEASALYSGPFPIHFHLKMDTGMGRLGVKDEEETKRIVALIERHPHFVLEGLYTHFATADEVNTDYFSYQYTRFLHMLEWLPSRPPLVHCANSAASLRFPDRTFNMVRFGIAMYGLAPSPGIKPLLPYPLKEAFSLHSRLVHVKKLQPGEKVSYGATYTAQTEEWIGTIPIGYADGWLRRLQHFHVLVDGQKAPIVGRICMDQCMIRLPGPLPVGTKVTLIGRQGDEVISIDDVARHLETINYEVPCTISYRVPRIFFRHKRIMEVRNAIGRGESSA", "length": 388, "reference_go_mf": ["GO:0008784", "GO:0030170"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_d33cabf0ffae6e4b28e5"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P10724", "alignment_score": 756.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 383], "sequence": "MNDFHRDTWAEVDLDAIYDNVENLRRLLPDDTHIMAVVKANAYGHGDVQVARTALEAGASRLAVAFLDEALALREKGIEAPILVLGASRPADAALAAQQRIALTVFRSDWLEEASALYSGPFPIHFHLKMDTGMGRLGVKDEEETKRIVALIERHPHFVLEGLYTHFATADEVNTDYFSYQYTRFLHMLEWLPSRPPLVHCANSAASLRFPDRTFNMVRFGIAMYGLAPSPGIKPLLPYPLKEAFSLHSRLVHVKKLQPGEKVSYGATYTAQTEEWIGTIPIGYADGWLRRLQHFHVLVDGQKAPIVGRICMDQCMIRLPGPLPVGTKVTLIGRQGDEVISIDDVARHLETINYEVPCTISYRVPRIFFRHKRIMEVRNAIGRGESSA", "length": 388, "reference_go_mf": ["GO:0008784", "GO:0030170"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_d33cabf0ffae6e4b28e5"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_214_1ecf_assembly1", "enzyme_name": "amidophosphoribosyltransferase", "ec": ["2.4.2.14"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0AG16", "alignment_score": 984.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 493], "sequence": "MCGIVGIAGVMPVNQSIYDALTVLQHRGQDAAGIITIDANNCFRLRKANGLVSDVFEARHMQRLQGNMGIGHVRYPTAGSSSASEAQPFYVNSPYGITLAHNGNLTNAHELRKKLFEEKRRHINTTSDSEILLNIFASELDNFRHYPLEADNIFAAIAATNRLIRGAYACVAMIIGHGMVAFRDPNGIRPLVLGKRDIDENRTEYMVASESVALDTLGFDFLRDVAPGEAIYITEEGQLFTRQCADNPVSNPCLFEYVYFARPDSFIDKISVYSARVNMGTKLGEKIAREWEDLDIDVVIPIPETSCDIALEIARILGKPYRQGFVKNRYVGRTFIMPGQQLRRKSVRRKLNANRAEFRDKNVLLVDDSIVRGTTSEQIIEMAREAGAKKVYLASAAPEIRFPNVYGIDMPSATELIAHGREVDEIRQIIGADGLIFQDLNDLIDAVRAENPDIQQFECSVFNGVYVTKDVDQGYLDFLDTLRNDDAKAVQRQNEVENLEMHNEG", "length": 505, "reference_go_mf": ["GO:0004044", "GO:0016757", "GO:0097216", "GO:0042802", "GO:0000287"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_ceec3aa79eb55fedf637"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_215_1pvd_assembly1", "enzyme_name": "pyruvate decarboxylase", "ec": ["4.1.1.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P06169", "alignment_score": 1045.0, "observed_coverage": 1.0, "aligned_identity": 0.994413407821229, "canonical_span": [1, 556], "sequence": "MSEITLGKYLFERLKQVNVNTVFGLPGDFNLSLLDKIYEVEGMRWAGNANELNAAYAADGYARIKGMSCIITTFGVGELSALNGIAGSYAEHVGVLHVVGVPSISAQAKQLLLHHTLGNGDFTVFHRMSANISETTAMITDIATAPAEIDRCIRTTYVTQRPVYLGLPANLVDLNVPAKLLQTPIDMSLKPNDAESEKEVIDTILALVKDAKNPVILADACCSRHDVKAETKKLIDLTQFPAFVTPMGKGSIDEQHPRYGGVYVGTLSKPEVKEAVESADLILSVGALLSDFNTGSFSYSYKTKNIVEFHSDHMKIRNATFPGVQMKFVLQKLLTTIADAAKGYKPVAVPARTPANAAVPASTPLKQEWMWNQLGNFLQEGDVVIAETGTSAFGINQTTFPNNTYGISQVLWGSIGFTTGATLGAAFAAEEIDPKKRVILFIGDGSLQLTVQEISTMIRWGLKPYLFVLNNDGYTIEKLIHGPKAQYNEIQGWDHLSLLPTFGAKDYETHRVATTGEWDKLTQDKSFNDNSKIRMIEIMLPVFDAPQNLVEQAKLTAATNAKQ", "length": 563, "reference_go_mf": ["GO:0047433", "GO:0047434", "GO:0000287", "GO:0050177", "GO:0004737", "GO:0030976"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_bc28ae4d61606e486d19"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P06169", "alignment_score": 1045.0, "observed_coverage": 1.0, "aligned_identity": 0.994413407821229, "canonical_span": [1, 556], "sequence": "MSEITLGKYLFERLKQVNVNTVFGLPGDFNLSLLDKIYEVEGMRWAGNANELNAAYAADGYARIKGMSCIITTFGVGELSALNGIAGSYAEHVGVLHVVGVPSISAQAKQLLLHHTLGNGDFTVFHRMSANISETTAMITDIATAPAEIDRCIRTTYVTQRPVYLGLPANLVDLNVPAKLLQTPIDMSLKPNDAESEKEVIDTILALVKDAKNPVILADACCSRHDVKAETKKLIDLTQFPAFVTPMGKGSIDEQHPRYGGVYVGTLSKPEVKEAVESADLILSVGALLSDFNTGSFSYSYKTKNIVEFHSDHMKIRNATFPGVQMKFVLQKLLTTIADAAKGYKPVAVPARTPANAAVPASTPLKQEWMWNQLGNFLQEGDVVIAETGTSAFGINQTTFPNNTYGISQVLWGSIGFTTGATLGAAFAAEEIDPKKRVILFIGDGSLQLTVQEISTMIRWGLKPYLFVLNNDGYTIEKLIHGPKAQYNEIQGWDHLSLLPTFGAKDYETHRVATTGEWDKLTQDKSFNDNSKIRMIEIMLPVFDAPQNLVEQAKLTAATNAKQ", "length": 563, "reference_go_mf": ["GO:0047433", "GO:0047434", "GO:0000287", "GO:0050177", "GO:0004737", "GO:0030976"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_bc28ae4d61606e486d19"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_216_1ca2_assembly1", "enzyme_name": "carbonate dehydratase (alpha class)", "ec": ["4.2.1.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00918", "alignment_score": 512.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [3, 259], "sequence": "MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK", "length": 260, "reference_go_mf": ["GO:0004064", "GO:0004089", "GO:0018820", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_e6a24c903c1ef211037c"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_217_1sc9_assembly2", "enzyme_name": "(S)-hydroxynitrile lyase", "ec": ["4.1.2.47"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P52704", "alignment_score": 512.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 257], "sequence": "MAFAHFVLIHTICHGAWIWHKLKPLLEALGHKVTALDLAASGVDPRQIEEIGSFDEYSEPLLTFLEALPPGEKVILVGESCGGLNIAIAADKYCEKIAAAVFHNSVLPDTEHCPSYVVDKLMEVFPDWKDTTYFTYTKDGKEITGLKLGFTLLRENLYTLCGPEEYELAKMLTRKGSLFQNILAKRPFFTKEGYGSIKKIYVWTDQDEIFLPEFQLWQIENYKPDKVYKVEGGDHKLQLTKTKEIAEILQEVADTYN", "length": 257, "reference_go_mf": ["GO:0052891", "GO:0052892", "GO:0080030", "GO:0080032", "GO:0080031"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_3d240a7e93095799ff65"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_218_1hpl_assembly1", "enzyme_name": "triacylglycerol lipase (pancreatic)", "ec": ["3.1.1.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P29183", "alignment_score": 898.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [12, 461], "sequence": "WTLSLLLGAVVGNEVCYERLGCFSDDSPWAGIVERPLKILPWSPEKVNTRFLLYTNENPDNFQEIVADPSTIQSSNFNTGRKTRFIIHGFIDKGEESWLSTMCQNMFKVESVNCICVDWKSGSRTAYSQASQNVRIVGAEVAYLVGVLQSSFDYSPSNVHIIGHSLGSHAAGEAGRRTNGAVGRITGLDPAEPCFQGTPELVRLDPSDAQFVDVIHTDIAPFIPNLGFGMSQTAGHLDFFPNGGKEMPGCQKNVLSQIVDIDGIWQGTRDFAACNHLRSYKYYTDSILNPDGFAGFSCASYSDFTANKCFPCSSEGCPQMGHYADRFPGRTKGVGQLFYLNTGDASNFARWRYRVDVTLSGKKVTGHVLVSLFGNKGNSRQYEIFQGTLKPDNTYSNEFDSDVEVGDLEKVKFIWYNNVINLTLPKVGASKITVERNDGSVFNFCSEETVREDVLLTLTAC", "length": 461, "reference_go_mf": ["GO:0047376", "GO:0008970", "GO:0004465", "GO:0004806"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_e329fe0e8f1cd9d0d444"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_21_1do8_assembly1", "enzyme_name": "malate dehydrogenase (oxaloacetate-decarboxylating)", "ec": ["1.1.1.38"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P23368", "alignment_score": 996.5, "observed_coverage": 1.0, "aligned_identity": 0.9981447124304267, "canonical_span": [20, 573], "sequence": "MLSRLRVVSTTCTLACRHLHIKEKGKPLMLNPRTNKGMAFTLQERQMLGLQGLLPPKIETQDIQALRFHRNLKKMTSPLEKYIYIMGIQERNEKLFYRILQDDIESLMPIVYTPTVGLACSQYGHIFRRPKGLFISISDRGHVRSIVDNWPENHVKAVVVTDGERILGLGDLGVYGMGIPVGKLCLYTACAGIRPDRCLPVCIDVGTDNIALLKDPFYMGLYQKRDRTQQYDDLIDEFMKAITDRYGRNTLIQFEDFGNHNAFRFLRKYREKYCTFNDDIQGTAAVALAGLLAAQKVISKPISEHKILFLGAGEAALGIANLIVMSMVENGLSEQEAQKKIWMFDKYGLLVKGRKAKIDSYQEPFTHSAPESIPDTFEDAVNILKPSTIIGVAGAGRLFTPDVIRAMASINERPVIFALSNPTAQAECTAEEAYTLTEGRCLFASGSPFGPVKLTDGRVFTPGQGNNVYIFPGVALAVILCNTRHISDSVFLEAAKALTSQLTDEELAQGRLYPPLANIQEVSINIAIKVTEYLYANKMAFRYPEPEDKAKYVKERTWRSEYDSLLPDVYEWPESASSPPVITE", "length": 584, "reference_go_mf": ["GO:0009055", "GO:0004471", "GO:0004470", "GO:0051287", "GO:0008948"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_dffbbceb24bea4441673"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_221_2ag0_assembly1", "enzyme_name": "benzoin aldolase", "ec": ["4.1.2.38"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q9F4L3", "alignment_score": 1108.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 555], "sequence": "MAMITGGELVVRTLIKAGVEHLFGLHGAHIDTIFQACLDHDVPIIDTRHEAAAGHAAEGYARAGAKLGVALVTAGGGFTNAVTPIANAWLDRTPVLFLTGSGALRDDETNTLQAGIDQVAMAAPITKWAHRVMATEHIPRLVMQAIRAALSAPRGPVLLDLPWDILMNQIDEDSVIIPDLVLSAHGARPDPADLDQALALLRKAERPVIVLGSEASRTARKTALSAFVAATGVPVFADYEGLSMLSGLPDAMRGGLVQNLYSFAKADAAPDLVLMLGARFGLNTGHGSGQLIPHSAQVIQVDPDACELGRLQGIALGIVADVGGTIEALAQATAQDAAWPDRGDWCAKVTDLAQERYASIAAKSSSEHALHPFHASQVIAKHVDAGVTVVADGALTYLWLSEVMSRVKPGGFLCHGYLGSMGVGFGTALGAQVADLEAGRRTILVTGDGSVGYSIGEFDTLVRKQLPLIVIIMNNQSWGATLHFQQLAVGPNRVTGTRLENGSYHGVAAAFGADGYHVDSVESFSAALAQALAHNRPACINVAVALDPIPPEELILIGMDPFA", "length": 563, "reference_go_mf": ["GO:0003984", "GO:0050660", "GO:0000287", "GO:0030976"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_59479593974b27c37b3f"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "Q9F4L3", "alignment_score": 1108.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 555], "sequence": "MAMITGGELVVRTLIKAGVEHLFGLHGAHIDTIFQACLDHDVPIIDTRHEAAAGHAAEGYARAGAKLGVALVTAGGGFTNAVTPIANAWLDRTPVLFLTGSGALRDDETNTLQAGIDQVAMAAPITKWAHRVMATEHIPRLVMQAIRAALSAPRGPVLLDLPWDILMNQIDEDSVIIPDLVLSAHGARPDPADLDQALALLRKAERPVIVLGSEASRTARKTALSAFVAATGVPVFADYEGLSMLSGLPDAMRGGLVQNLYSFAKADAAPDLVLMLGARFGLNTGHGSGQLIPHSAQVIQVDPDACELGRLQGIALGIVADVGGTIEALAQATAQDAAWPDRGDWCAKVTDLAQERYASIAAKSSSEHALHPFHASQVIAKHVDAGVTVVADGALTYLWLSEVMSRVKPGGFLCHGYLGSMGVGFGTALGAQVADLEAGRRTILVTGDGSVGYSIGEFDTLVRKQLPLIVIIMNNQSWGATLHFQQLAVGPNRVTGTRLENGSYHGVAAAFGADGYHVDSVESFSAALAQALAHNRPACINVAVALDPIPPEELILIGMDPFA", "length": 563, "reference_go_mf": ["GO:0003984", "GO:0050660", "GO:0000287", "GO:0030976"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_59479593974b27c37b3f"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_222_2qut_assembly1", "enzyme_name": "fructose-bisphosphate aldolase (Class I)", "ec": ["4.1.2.13"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00883", "alignment_score": 690.0, "observed_coverage": 0.9857142857142858, "aligned_identity": 1.0, "canonical_span": [1, 346], "sequence": "MPHSHPALTPEQKKELSDIAHRIVAPGKGILAADESTGSIAKRLQSIGTENTEENRRFYRQLLLTADDRVNPCIGGVILFHETLYQKADDGRPFPQVIKSKGGVVGIKVDKGVVPLAGTNGETTTQGLDGLSERCAQYKKDGADFAKWRCVLKIGEHTPSALAIMENANVLARYASICQQNGIVPIVEPEILPDGDHDLKRCQYVTEKVLAAVYKALSDHHIYLEGTLLKPNMVTPGHACTQKYSHEEIAMATVTALRRTVPPAVTGVTFLSGGQSEEEASINLNAINKCPLLKPWALTFSYGRALQASALKAWGGKKENLKAAQEEYVKRALANSLACQGKYTPSGQAGAAASESLFISNHAY", "length": 364, "reference_go_mf": ["GO:0004332"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_c914da2418e4f7c20459"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_225_1vr7_assembly1", "enzyme_name": "adenosylmethionine decarboxylase (prokaryotic)", "ec": ["4.1.1.50"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q9WZC3", "alignment_score": 232.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 121], "sequence": "MKSLGRHLVAEFYECDREVLDNVQLIEQEMKQAAYESGATIVTSTFHRFLPYGVSGVVVISESHLTIHTWPEYGYAAIDLFTCGEDVDPWKAFEHLKKALKAKRVHVVEHERGRYDEIGIPEDSPHKAAV", "length": 130, "reference_go_mf": ["GO:0004014"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_3e266db66beb0eb90d6f"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "Q9WZC3", "alignment_score": 226.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 118], "sequence": "MKSLGRHLVAEFYECDREVLDNVQLIEQEMKQAAYESGATIVTSTFHRFLPYGVSGVVVISESHLTIHTWPEYGYAAIDLFTCGEDVDPWKAFEHLKKALKAKRVHVVEHERGRYDEIGIPEDSPHKAAV", "length": 130, "reference_go_mf": ["GO:0004014"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_3e266db66beb0eb90d6f"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_226_1qrr_assembly1", "enzyme_name": "UDP-sulfoquinovose synthase", "ec": ["3.13.1.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "O48917", "alignment_score": 780.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [84, 474], "sequence": "MAHLLSASCPSVISLSSSSSKNSVKPFVSGQTFFNAQLLSRSSLKGLLFQEKKPRKSCVFRATAVPITQQAPPETSTNNSSSKPKRVMVIGGDGYCGWATALHLSKKNYEVCIVDNLVRRLFDHQLGLESLTPIASIHDRISRWKALTGKSIELYVGDICDFEFLAESFKSFEPDSVVHFGEQRSAPYSMIDRSRAVYTQHNNVIGTLNVLFAIKEFGEECHLVKLGTMGEYGTPNIDIEEGYITITHNGRTDTLPYPKQASSFYHLSKVHDSHNIAFTCKAWGIRATDLNQGVVYGVKTDETEMHEELRNRLDYDAVFGTALNRFCVQAAVGHPLTVYGKGGQTRGYLDIRDTVQCVEIAIANPAKAGEFRVFNQFTEQFSVNELASLVTKAGSKLGLDVKKMTVPNPRVEAEEHYYNAKHTKLMELGLEPHYLSDSLLDSLLNFAVQFKDRVDTKQIMPSVSWKKIGVKTKSMTT", "length": 477, "reference_go_mf": ["GO:0008146", "GO:0046507", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_9a6ef35d64f7e22b106c"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_227_1e6u_assembly1", "enzyme_name": "GDP-L-fucose synthase", "ec": ["1.1.1.271"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P32055", "alignment_score": 625.0, "observed_coverage": 0.9968253968253968, "aligned_identity": 0.9968152866242038, "canonical_span": [2, 316], "sequence": "MSKQRVFIAGHRGMVGSAIRRQLEQRGDVELVLRTRDELNLLDSRAVHDFFASERIDQVYLAAAKVGGIVANNTYPADFIYQNMMIESNIIHAAHQNDVNKLLFLGSSCIYPKLAKQPMAESELLQGTLEPTNEPYAIAKIAGIKLCESYNRQYGRDYRSVMPTNLYGPHDNFHPSNSHVIPALLRRFHEATAQNAPDVVVWGSGTPMREFLHVDDMAAASIHVMELAHEVWLENTQPMLSHINVGTGVDCTIRELAQTIAKVVGYKGRVVFDASKPDGTPRKLLDVTRLHQLGWYHEISLEAGLASTYQWFLENQDRFRG", "length": 321, "reference_go_mf": ["GO:0050577", "GO:0070401", "GO:0042803"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_5759da3e7fd9d6e38286"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_228_1bxk_assembly1", "enzyme_name": "dTDP-glucose 4,6-dehydratase", "ec": ["4.2.1.46"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P27830", "alignment_score": 666.0, "observed_coverage": 1.0, "aligned_identity": 0.9941348973607038, "canonical_span": [0, 350], "sequence": "MRKILITGGAGFIGSALVRYIINETSDAVVVVDKLTYAGNLMSLAPVAQSERFAFEKVDICDRAELARVFTEHQPDCVMHLAAESHVDRSIDGPAAFIETNIVGTYTLLEAARAYWNALTEDKKSAFRFHHISTDEVYGDLHSTDDFFTETTPYAPSSPYSASKASSDHLVRAWLRTYGLPTLITNCSNNYGPYHFPEKLIPLMILNALAGKSLPVYGNGQQIRDWLYVEDHARALYCVATTGKVGETYNIGGHNERKNLDVVETICELLEELAPNKPHGVAHYRDLITFVADRPGHDLRYAIDASKIARELGWLPQETFESGMRKTVQWYLANESWWKQVQDGSYQGERLGLKG", "length": 355, "reference_go_mf": ["GO:0008460"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_c11f03829d78434f69fa"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_229_2a84_assembly1", "enzyme_name": "pantoate-beta-alanine ligase", "ec": ["6.3.2.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P9WIL5", "alignment_score": 543.5, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [2, 289], "sequence": "MTIPAFHPGELNVYSAPGDVADVSRALRLTGRRVMLVPTMGALHEGHLALVRAAKRVPGSVVVVSIFVNPMQFGAGEDLDAYPRTPDDDLAQLRAEGVEIAFTPTTAAMYPDGLRTTVQPGPLAAELEGGPRPTHFAGVLTVVLKLLQIVRPDRVFFGEKDYQQLVLIRQLVADFNLDVAVVGVPTVREADGLAMSSRNRYLDPAQRAAAVALSAALTAAAHAATAGAQAALDAARAVLDAAPGVAVDYLELRDIGLGPMPLNGSGRLLVAARLGTTRLLDNIAIEIGTFAGTDRPDGYRAILESHWRN", "length": 309, "reference_go_mf": ["GO:0005524", "GO:0000287", "GO:0030145", "GO:0004592"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_7afdd04f12b89bfd537d"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_22_1b6b_assembly1", "enzyme_name": "aralkylamine N-acetyltransferase", "ec": ["2.3.1.87"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q29495", "alignment_score": 336.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [33, 201], "sequence": "MSTPSVHCLKPSPLHLPSGIPGSPGRQRRHTLPANEFRCLTPEDAAGVFEIEREAFISVSGNCPLNLDEVQHFLTLCPELSLGWFVEGRLVAFIIGSLWDEERLTQESLALHRPRGHSAHLHALAVHRSFRQQGKGSVLLWRYLHHVGAQPAVRRAVLMCEDALVPFYQRFGFHPAGPCAIVVGSLTFTEMHCSLRGHAALRRNSDR", "length": 207, "reference_go_mf": ["GO:0004059"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_0c5493f546d07028533d"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_231_1uw8_assembly1", "enzyme_name": "oxalate decarboxylase", "ec": ["4.1.1.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "O34714", "alignment_score": 754.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [5, 382], "sequence": "MKKQNDIPQPIRGDKGATVKIPRNIERDRQNPDMLVPPETDHGTVSNMKFSFSDTHNRLEKGGYAREVTVRELPISENLASVNMRLKPGAIRELHWHKEAEWAYMIYGSARVTIVDEKGRSFIDDVGEGDLWYFPSGLPHSIQALEEGAEFLLVFDDGSFSENSTFQLTDWLAHTPKEVIAANFGVTKEEISNLPGKEKYIFENQLPGSLKDDIVEGPNGEVPYPFTYRLLEQEPIESEGGKVYIADSTNFKVSKTIASALVTVEPGAMRELHWHPNTHEWQYYISGKARMTVFASDGHARTFNYQAGDVGYVPFAMGHYVENIGDEPLVFLEIFKDDHYADVSLNQWLAMLPETFVQAHLDLGKDFTDVLSKEKHPVVKKKCSK", "length": 385, "reference_go_mf": ["GO:0046564"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_73c316e05811784e2650"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_233_1g9z_assembly1", "enzyme_name": "DNA endonuclease I-CreI", "ec": ["3.1.21.-"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P05725", "alignment_score": 304.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 153], "sequence": "MNTKYNKEFLLYLAGFVDGDGSIIAQIKPNQSYKFKHQLSLTFQVTQKTQRRWFLDKLVDEIGVGYVRDRGSVSDYILSEIKPLHNFLTQLQPFLKLKQKQANLVLKIIEQLPSAKESPDKFLEVCTWVDQIAALNDSKTRKTTSETVRAVLDSLSEKKKSSP", "length": 163, "reference_go_mf": ["GO:0004519", "GO:0042802"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_4eaa92f68ea5f77ed571"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P05725", "alignment_score": 304.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 153], "sequence": "MNTKYNKEFLLYLAGFVDGDGSIIAQIKPNQSYKFKHQLSLTFQVTQKTQRRWFLDKLVDEIGVGYVRDRGSVSDYILSEIKPLHNFLTQLQPFLKLKQKQANLVLKIIEQLPSAKESPDKFLEVCTWVDQIAALNDSKTRKTTSETVRAVLDSLSEKKKSSP", "length": 163, "reference_go_mf": ["GO:0004519", "GO:0042802"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_4eaa92f68ea5f77ed571"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_234_1gpm_assembly1", "enzyme_name": "GMP synthase (glutamine-hydrolysing)", "ec": ["6.3.5.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P04079", "alignment_score": 985.5, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [2, 525], "sequence": "MTENIHKHRILILDFGSQYTQLVARRVRELGVYCELWAWDVTEAQIRDFNPSGIILSGGPESTTEENSPRAPQYVFEAGVPVFGVCYGMQTMAMQLGGHVEASNEREFGYAQVEVVNDSALVRGIEDALTADGKPLLDVWMSHGDKVTAIPSDFITVASTESCPFAIMANEEKRFYGVQFHPEVTHTRQGMRMLERFVRDICQCEALWTPAKIIDDAVARIREQVGDDKVILGLSGGVDSSVTAMLLHRAIGKNLTCVFVDNGLLRLNEAEQVLDMFGDHFGLNIVHVPAEDRFLSALAGENDPEAKRKIIGRVFVEVFDEEALKLEDVKWLAQGTIYPDVIESAASATGKAHVIKSHHNVGGLPKEMKMGLVEPLKELFKDEVRKIGLELGLPYDMLYRHPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELRKADLYDKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDFMTAHWAHLPYDFLGRVSNRIINEVNGISRVVYDISGKPPATIEWE", "length": 525, "reference_go_mf": ["GO:0005524", "GO:0003922", "GO:0003921", "GO:0042802"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_4a91e8a921fdb070aa6d"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_235_1f7u_assembly1", "enzyme_name": "arginine-tRNA ligase", "ec": ["6.1.1.19"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q05506", "alignment_score": 1212.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 607], "sequence": "MASTANMISQLKKLSIAEPAVAKDSHPDVNIVDLMRNYISQELSKISGVDSSLIFPALEWTNTMERGDLLIPIPRLRIKGANPKDLAVQWAEKFPCGDFLEKVEANGPFIQFFFNPQFLAKLVIPDILTRKEDYGSCKLVENKKVIIEFSSPNIAKPFHAGHLRSTIIGGFLANLYEKLGWEVIRMNYLGDWGKQFGLLAVGFERYGNEEALVKDPIHHLFDVYVRINKDIEEEGDSIPLEQSTNGKAREYFKRMEDGDEEALKIWKRFREFSIEKYIDTYARLNIKYDVYSGESQVSKESMLKAIDLFKEKGLTHEDKGAVLIDLTKFNKKLGKAIVQKSDGTTLYLTRDVGAAMDRYEKYHFDKMIYVIASQQDLHAAQFFEILKQMGFEWAKDLQHVNFGMVQGMSTRKGTVVFLDNILEETKEKMHEVMKKNENKYAQIEHPEEVADLVGISAVMIQDMQGKRINNYEFKWERMLSFEGDTGPYLQYAHSRLRSVERNASGITQEKWINADFSLLKEPAAKLLIRLLGQYPDVLRNAIKTHEPTTVVTYLFKLTHQVSSCYDVLWVAGQTEELATARLALYGAARQVLYNGMRLLGLTPVERM", "length": 607, "reference_go_mf": ["GO:0004814", "GO:0005524", "GO:1990825"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_7fdfbfb61a6a86651fa2"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_236_1q6l_assembly1", "enzyme_name": "3-dehydro-L-gulonate-6-phosphate decarboxylase", "ec": ["4.1.1.85"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P39304", "alignment_score": 428.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 215], "sequence": "MSLPMLQVALDNQTMDSAYETTRLIAEEVDIIEVGTILCVGEGVRAVRDLKALYPHKIVLADAKIADAGKILSRMCFEANADWVTVICCADINTAKGALDVAKEFNGDVQIELTGYWTWEQAQQWRDAGIGQVVYHRSRDAQAAGVAWGEADITAIKRLSDMGFKVTVTGGLALEDLPLFKGIPIHVFIAGRSIRDAASPVEAARQFKRSIAELWG", "length": 216, "reference_go_mf": ["GO:0033982", "GO:0000287", "GO:0004590"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_0720f3f8f3739ea0ec39"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P39304", "alignment_score": 430.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 216], "sequence": "MSLPMLQVALDNQTMDSAYETTRLIAEEVDIIEVGTILCVGEGVRAVRDLKALYPHKIVLADAKIADAGKILSRMCFEANADWVTVICCADINTAKGALDVAKEFNGDVQIELTGYWTWEQAQQWRDAGIGQVVYHRSRDAQAAGVAWGEADITAIKRLSDMGFKVTVTGGLALEDLPLFKGIPIHVFIAGRSIRDAASPVEAARQFKRSIAELWG", "length": 216, "reference_go_mf": ["GO:0033982", "GO:0000287", "GO:0004590"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_0720f3f8f3739ea0ec39"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_237_2c7v_assembly1", "enzyme_name": "pteridine reductase", "ec": ["1.5.1.33"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "O76290", "alignment_score": 472.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 268], "sequence": "MEAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGDHEDNSNGKTVETQVAELIGTNAIAPFLLTMSFAQRQKGTNPNCTSSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA", "length": 268, "reference_go_mf": ["GO:0047040"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_91097f1d4017c6545782"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_238_1wpo_assembly1", "enzyme_name": "assemblin", "ec": ["3.4.21.97"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P16753", "alignment_score": 347.5, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [8, 256], "sequence": "MTMDEQQSQAVAPVYVGGFLARYDQSPDEAELLLPRDVVEHWLHAQGQGQPSLSVALPLNINHDDTAVVGHVAAMQSVRDGLFCLGCVTSPRFLEIVRRASEKSELVSRGPVSPLQPDKVVEFLSGSYAGLSLSSRRCDDVEAATSLSGSETTPFKHVALCSVGRRRGTLAVYGRDPEWVTQRFPDLTAADRDGLRAQWQRCGSTAVDASGDPFRSDSYGLLGNSVDALYIRERLPKLRYDKQLVGVTERESYVKASVSPEAACDIKAASAERSGDSRSQAATPAAGARVPSSSPSPPVEPPSPVQPPALPASPSVLPAESPPSLSPSEPAEAASMSHPLSAAVPAATAPPGATVAGASPAVSSLAWPHDGVYLPKDAFFSLLGASRSAVPVMYPGAVAAPPSASPAPLPLPSYPASYGAPVVGYDQLAARHFADYVDPHYPGWGRRYEPAPSLHPSYPVPPPPSPAYYRRRDSPGGMDEPPSGWERYDGGHRGQSQKQHRHGGSGGHNKRRKETAAASSSSSDEDLSFPGEAEHGRARKRLKSHVNSDGGSGGHAGSNQQQQQRYDELRDAIHELKRDLFAARQSSTLLSAALPSAASSSPTTTTVCTPTGELTSGGGETPTALLSGGAKVAERAQAGVVNASCRLATASGSEAATAGPSTAGSSSCPASVVLAAAAAQAAAASQSPPKDMVDLNRRIFVAALNKLE", "length": 708, "reference_go_mf": ["GO:0042802", "GO:0004252"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_8f1ddb36b5b9074dbb0b"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_239_7atj_assembly1", "enzyme_name": "peroxidase", "ec": ["1.11.1.7"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00433", "alignment_score": 610.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [30, 335], "sequence": "MHFSSSSTLFTCITLIPLVCLILHASLSDAQLTPTFYDNSCPNVSNIVRDTIVNELRSDPRIAASILRLHFHDCFVNGCDASILLDNTTSFRTEKDAFGNANSARGFPVIDRMKAAVESACPRTVSCADLLTIAAQQSVTLAGGPSWRVPLGRRDSLQAFLDLANANLPAPFFTLPQLKDSFRNVGLNRSSDLVALSGGHTFGKNQCRFIMDRLYNFSNTGLPDPTLNTTYLQTLRGLCPLNGNLSALVDFDLRTPTIFDNKYYVNLEEQKGLIQSDQELFSSPNATDTIPLVRSFANSTQTFFNAFVEAMDRMGNITPLTGTQGQIRLNCRVVNSNSLLHDMVEVVDFVSSM", "length": 353, "reference_go_mf": ["GO:0020037", "GO:0140825"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_5e962f6b9c3e7eed62e1"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_23_1xva_assembly1", "enzyme_name": "glycine N-methyltransferase", "ec": ["2.1.1.20"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P13255", "alignment_score": 584.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 293], "sequence": "MVDSVYRTRSLGVAAEGIPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCHRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRKEPAFDKWVIEEANWLTLDKDVPAGDGFDAVICLGNSFAHLPDSKGDQSEHRLALKNIASMVRPGGLLVIDHRNYDYILSTGCAPPGKNIYYKSDLTKDITTSVLTVNNKAHMVTLDYTVQVPGAGRDGAPGFSKFRLSYYPHCLASFTELVQEAFGGRCQHSVLGDFKPYRPGQAYVPCYFIHVLKKTG", "length": 293, "reference_go_mf": ["GO:0005542", "GO:0016594", "GO:0017174", "GO:0042802", "GO:1904047", "GO:0098603"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_3c263895c338f47a66ad"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_240_1szd_assembly1", "enzyme_name": "histone/protein deacetylase", "ec": ["3.5.1.98"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P53686", "alignment_score": 568.0, "observed_coverage": 0.9896907216494846, "aligned_identity": 1.0, "canonical_span": [0, 293], "sequence": "MSVSTASTEMSVRKIAAHMKSNPNAKVIFMVGAGISTSCGIPDFRSPGTGLYHNLARLKLPYPEAVFDVDFFQSDPLPFYTLAKELYPGNFRPSKFHYLLKLFQDKDVLKRVYTQNIDTLERQAGVKDDLIIEAHGSFAHCHCIGCGKVYPPQVFKSKLAEHPIKDFVKCDVCGELVKPAIVFFGEDLPDSFSETWLNDSEWLREKITTSGKHPQQPLVIVVGTSLAVYPFASLPEEIPRKVKRVLCNLETVGDFKANKRPTDLIVHQYSDEFAEQLVEELGWQEDFEKILTAQGGMGDNSKEQLLEIVHDLENLSLDQSEHESADKKDKKLQRLNGHDSDEDGASNSSSSQKAAKE", "length": 357, "reference_go_mf": ["GO:0017136", "GO:0046970", "GO:0070403"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_e7ad900ac4e214080ff5"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_241_3pva_assembly1", "enzyme_name": "penicillin amidase (peptidase C59 family)", "ec": ["3.5.1.11"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P12256", "alignment_score": 668.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [3, 337], "sequence": "MLGCSSLSIRTTDDKSLFARTMDFTMEPDSKVIIVPRNYGIRLLEKENVVINNSYAFVGMGSTDITSPVLYDGVNEKGLMGAMLYYATFATYADEPKKGTTGINPVYVISQVLGNCVTVDDVIEKLTSYTLLNEANIILGFAPPLHYTFTDASGESIVIEPDKTGITIHRKTIGVMTNSPGYEWHQTNLRAYIGVTPNPPQDIMMGDLDLTPFGQGAGGLGLPGDFTPSARFLRVAYWKKYTEKAKNETEGVTNLFHILSSVNIPKGVVLTNEGKTDYTIYTSAMCAQSKNYYFKLYDNSRISAVSLMAENLNSQDLITFEWDRKQDIKQLNQVNVMS", "length": 338, "reference_go_mf": ["GO:0008953"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_0f89d5e433a9647d9dff"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_246_1ir3_assembly1", "enzyme_name": "receptor protein-tyrosine kinase", "ec": ["2.7.10.1"], "controls": [{"chain": "A", "status": "reference_overlength", "selected": {"accession": "P06213", "alignment_score": 582.5, "observed_coverage": 0.9966666666666667, "aligned_identity": 0.9966555183946488, "canonical_span": [1008, 1310], "sequence": "MATGGRRGAAAAPLLVAVAALLLGAAGHLYPGEVCPGMDIRNNLTRLHELENCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNEECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSECLGNCSQPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHHKCKNSRRQGCHQYVIHNNKCIPECPSGYTMNSSNLLCTPCLGPCPKVCHLLEGEKTIDSVTSAQELRGCTVINGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETLEIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQERNDIALKTNGDQASCENELLKFSYIRTSFDKILLRWEPYWPPDFRDLLGFMLFYKEAPYQNVTEFDGQDACGSNSWTVVDIDPPLRSNDPKSQNHPGWLMRGLKPWTQYAIFVKTLVTFSDERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWERQAEDSELFELDYCLKGLKLPSRTWSPPFESEDSQKHNQSEYEDSAGECCSCPKTDSQILKELEESSFRKTFEDYLHNVVFVPRKTSSGTGAEDPRPSRKRRSLGDVGNVTVAVPTVAAFPNTSSTSVPTSPEEHRPFEKVVNKESLVISGLRHFTGYRIELQACNQDTPEERCSVAAYVSARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCVSRKHFALERGCRLRGLSPGNYSVRIRATSLAGNGSWTEPTYFYVTDYLDVPSNIAKIIIGPLIFVFLFSVVIGSIYLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVSREKITLLRELGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASLRERIEFLNEASVMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMAAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDNCPERVTDLMRMCWQFNPKMRPTFLEIVNLLKDDLHPSFPEVSFFHSEENKAPESEELEMEFEDMENVPLDRSSHCQREEAGGRDGGSSLGFKRSYEEHIPYTHMNGGKKNGRILTLPRSNPS", "length": 1382, "reference_go_mf": ["GO:0001540", "GO:0005524", "GO:0038024", "GO:0005525", "GO:0042802", "GO:0043559", "GO:0005009", "GO:0043560", "GO:0031994", "GO:0031995", "GO:0005159", "GO:0043548", "GO:0019904", "GO:0030295", "GO:0004713", "GO:0044877", "GO:0051425"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_247_1kzl_assembly1", "enzyme_name": "riboflavin synthase", "ec": ["2.5.1.9"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q9Y7P0", "alignment_score": 404.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 202], "sequence": "MFTGLVEAIGVVKDVQGTIDNGFAMKIEAPQILDDCHTGDSIAVNGTCLTVTDFDRYHFTVGIAPESLRLTNLGQCKAGDPVNLERAVLSSTRMGGHFVQGHVDTVAEIVEKKQDGEAIDFTFRPRDPFVLKYIVYKGYIALDGTSLTITHVDDSTFSIMMISYTQSKVIMAKKNVGDLVNVEVDQIGKYTEKLVEAHIADWIKKTQA", "length": 208, "reference_go_mf": ["GO:0004746"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_f5ccb62023f861a1b120"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_249_1dty_assembly1", "enzyme_name": "adenosylmethionine--8-amino-7-oxononanoate transaminase", "ec": ["2.6.1.62"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P12995", "alignment_score": 843.0, "observed_coverage": 1.0, "aligned_identity": 0.9883449883449883, "canonical_span": [0, 429], "sequence": "MTTDDLAFDQRHIWHPYTSMTSPLPVYPVVSAEGCELILSDGRRLVDGMSSWWAAIHGYNHPQLNAAMKSQIDAMSHVMFGGITHAPAIELCRKLVAMTPQPLECVFLADSGSVAVEVAMKMALQYWQAKGEARQRFLTFRNGYHGDTFGAMSVCDPDNSMHSLWKGYLPENLFAPAPQSRMDGEWDERDMVGFARLMAAHRHEIAAVIIEPIVQGAGGMRMYHPEWLKRIRKICDREGILLIADEIATGFGRTGKLFACEHAEIAPDILCLGKALTGGTMTLSATLTTREVAETISNGEAGCFMHGPTFMGNPLACAAANASLAILESGDWQQQVADIEVQLREQLAPARDAEMVADVRVLGAIGVVETTHPVNMAALQKFFVEQGVWIRPFGKLIYLMPPYIILPQQLQRLTAAVNRAVQDETFFCQ", "length": 429, "reference_go_mf": ["GO:0042803", "GO:0030170", "GO:0004015"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_fe8c53a36cc733ca7eae"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_24_1nzy_assembly2", "enzyme_name": "4-chlorobenzoyl-CoA dehalogenase", "ec": ["3.8.1.7"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "A5JTM5", "alignment_score": 529.0, "observed_coverage": 1.0, "aligned_identity": 0.9888475836431226, "canonical_span": [0, 269], "sequence": "MYEAIGHRVEDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGFYLREIPLDKGVAGVRDHFRIGALWWHQMIHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADSAKFVCAWHTIGIGNDTATSYSLARIVGMRRAMELMLTNRTLYPEEAKDWGLVSRVYPKDDFREVAWKVARELAAAPTHLQVMAKERFHAGWMQPVEECTEFEIQNVIASVTHPHFMPCLTEFLDGHRADRPQVELPAGV", "length": 269, "reference_go_mf": ["GO:0018787"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_ab7f67bb165232f0db72"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_250_2cpo_assembly1", "enzyme_name": "chloride peroxidase (heme dependent)", "ec": ["1.11.1.10"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P04963", "alignment_score": 596.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [21, 319], "sequence": "MFSKVLPFVGAVAALPHSVRQEPGSGIGYPYDNNTLPYVAPGPTDSRAPCPALNALANHGYIPHDGRAISRETLQNAFLNHMGIANSVIELALTNAFVVCEYVTGSDCGDSLVNLTLLAEPHAFEHDHSFSRKDYKQGVANSNDFIDNRNFDAETFQTSLDVVAGKTHFDYADMNEIRLQRESLSNELDFPGWFTESKPIQNVESGFIFALVSDFNLPDNDENPLVRIDWWKYWFTNESFPYHLGWHPPSPAREIEFVTSASSAVLAASVTSTPSSLPSGAIGPGAEAVPLSFASTMTPFLLATNAPYYAQDPTLGPNDKREAAPAATTSMAVFKNPYLEAIGTQDIKNQQAYVSSKAAAMASAMAANKARNL", "length": 373, "reference_go_mf": ["GO:0016691"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_3b648eaede996ad505dc"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_251_1eh6_assembly1", "enzyme_name": "methylated-DNA--[protein]-cysteine S-methyltransferase", "ec": ["2.1.1.63"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P16455", "alignment_score": 326.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [4, 181], "sequence": "MDKDCEMKRTTLDSPLGKLELSGCEQGLHEIKLLGKGTSAADAVEVPAPAAVLGGPEPLMQCTAWLNAYFHQPEAIEEFPVPALHHPVFQQESFTRQVLWKLLKVVKFGEVISYQQLAALAGNPKAARAVGGAMRGNPVPILIPCHRVVCSSGAVGNYSGGLAVKEWLLAHEGHRLGKPGLGGSSGLAGAWLKGAGATSGSPPAGRN", "length": 207, "reference_go_mf": ["GO:0003677", "GO:0009008", "GO:0003908", "GO:0008168"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_f23ea8bb1edac597e621"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_252_1igs_assembly1", "enzyme_name": "indole-3-glycerol-phosphate synthase", "ec": ["4.1.1.48"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q06121", "alignment_score": 494.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 248], "sequence": "MPRYLKGWLKDVVQLSLRRPSFRASRQRPIISLNERILEFNKRNITAIIAEYKRKSPSGLDVERDPIEYSKFMERYAVGLSILTEEKYFNGSYETLRKIASSVSIPILMKDFIVKESQIDDAYNLGADTVLLIVKILTERELESLLEYARSYGMEPLIEINDENDLDIALRIGARFIGINSRDLETLEINKENQRKLISMIPSNVVKVAESGISERNEIEELRKLGVNAFLIGSSLMRNPEKIKEFIL", "length": 248, "reference_go_mf": ["GO:0004425"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_a5678301cecc2d1e4227"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_253_1fps_assembly1", "enzyme_name": "geranyltranstransferase", "ec": ["2.5.1.10"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P08836", "alignment_score": 696.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [19, 367], "sequence": "MHKFTGVNAKFQQPALRNLSPVVVEREREEFVGFFPQIVRDLTEDGIGHPEVGDAVARLKEVLQYNAPGGKCNRGLTVVAAYRELSGPGQKDAESLRCALAVGWCIELFQAFFLVADDIMDQSLTRRGQLCWYKKEGVGLDAINDSFLLESSVYRVLKKYCRQRPYYVHLLELFLQTAYQTELGQMLDLITAPVSKVDLSHFSEERYKAIVKYKTAFYSFYLPVAAAMYMVGIDSKEEHENAKAILLEMGEYFQIQDDYLDCFGDPALTGKVGTDIQDNKCSWLVVQCLQRVTPEQRQLLEDNYGRKEPEKVAKVKELYEAVGMRAAFQQYEESSYRRLQELIEKHSNRLPKEIFLGLAQKIYKRQK", "length": 367, "reference_go_mf": ["GO:0004337", "GO:0004161"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_946cbe864e05fdbf4196"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_254_1h3b_assembly1", "enzyme_name": "squalene-hopene cyclase", "ec": ["5.4.99.17"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P33247", "alignment_score": 1238.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [9, 628], "sequence": "MAEQLVEAPAYARTLDRAVEYLLSCQKDEGYWWGPLLSNVTMEAEYVLLCHILDRVDRDRMEKIRRYLLHEQREDGTWALYPGGPPDLDTTIEAYVALKYIGMSRDEEPMQKALRFIQSQGGIESSRVFTRMWLALVGEYPWEKVPMVPPEIMFLGKRMPLNIYEFGSWARATVVALSIVMSRQPVFPLPERARVPELYETDVPPRRRGAKGGGGWIFDALDRALHGYQKLSVHPFRRAAEIRALDWLLERQAGDGSWGGIQPPWFYALIALKILDMTQHPAFIKGWEGLELYGVELDYGGWMFQASISPVWDTGLAVLALRAAGLPADHDRLVKAGEWLLDRQITVPGDWAVKRPNLKPGGFAFQFDNVYYPDVDDTAVVVWALNTLRLPDERRRRDAMTKGFRWIVGMQSSNGGWGAYDVDNTSDLPNHIPFCDFGEVTDPPSEDVTAHVLECFGSFGYDDAWKVIRRAVEYLKREQKPDGSWFGRWGVNYLYGTGAVVSALKAVGIDTREPYIQKALDWVEQHQNPDGGWGEDCRSYEDPAYAGKGASTPSQTAWALMALIAGGRAESEAARRGVQYLVETQRPDGGWDEPYYTGTGFPGDFYLGYTMYRHVFPTLALGRYKQAIERR", "length": 631, "reference_go_mf": ["GO:0051007"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_122f9ecec8d9a3c4af24"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_255_1mg5_assembly1", "enzyme_name": "alcohol dehydrogenase (SDR type)", "ec": ["1.1.1.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00334", "alignment_score": 510.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 256], "sequence": "MSFTLTNKNVIFVAGLGGIGLDTSKELLKRDLKNLVILDRIENPAAIAELKAINPKVTVTFYPYDVTVPIAETTKLLKTIFAQLKTVDVLINGAGILDDHQIERTIAVNYTGLVNTTTAILDFWDKRKGGPGGIICNIGSVTGFNAIYQVPVYSGTKAAVVNFTSSLAKLAPITGVTAYTVNPGITRTTLVHKFNSWLDVEPQVAEKLLAHPTQPSLACAENFVKAIELNQNGAIWKLDLGTLEAIQWTKHWDSGI", "length": 256, "reference_go_mf": ["GO:0004022", "GO:0004029", "GO:0042803"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_7f68c130e655b7fd3b34"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_256_1qlh_assembly1", "enzyme_name": "alcohol dehydrogenase (class I)", "ec": ["1.1.1.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00327", "alignment_score": 742.0, "observed_coverage": 1.0, "aligned_identity": 0.9946524064171123, "canonical_span": [1, 375], "sequence": "MSTAGKVIKCKAAVLWEEKKPFSIEEVEVAPPKAHEVRIKMVATGICRSDDHVVSGTLVTPLPVIAGHEAAGIVESIGEGVTTVRPGDKVIPLFTPQCGKCRVCKHPEGNFCLKNDLSMPRGTMQDGTSRFTCRGKPIHHFLGTSTFSQYTVVDEISVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTQGSTCAVFGLGGVGLSVIMGCKAAGAARIIGVDINKDKFAKAKEVGATECVNPQDYKKPIQEVLTEMSNGGVDFSFEVIGRLDTMVTALSCCQEAYGVSVIVGVPPDSQNLSMNPMLLLSGRTWKGAIFGGFKSKDSVPKLVADFMAKKFALDPLITHVLPFEKINEGFDLLRSGESIRTILTF", "length": 375, "reference_go_mf": ["GO:0004745", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_5f674a2c7c6b8f349def"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_257_1xx2_assembly1", "enzyme_name": "beta-lactamase (Class C)", "ec": ["3.5.2.6"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P05364", "alignment_score": 718.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [21, 380], "sequence": "MMRKSLCCALLLGISCSALATPVSEKQLAEVVANTITPLMKAQSVPGMAVAVIYQGKPHYYTFGKADIAANKPVTPQTLFELGSISKTFTGVLGGDAIARGEISLDDAVTRYWPQLTGKQWQGIRMLDLATYTAGGLPLQVPDEVTDNASLLRFYQNWQPQWKPGTTRLYANASIGLFGALAVKPSGMPYEQAMTTRVLKPLKLDHTWINVPKAEEAHYAWGYRDGKAVRVSPGMLDAQAYGVKTNVQDMANWVMANMAPENVADASLKQGIALAQSRYWRIGSMYQGLGWEMLNWPVEANTVVEGSDSKVALAPLPVAEVNPPAPPVKASWVHKTGSTGGFGSYVAFIPEKQIGIVMLANTSYPNPARVEAAYHILEALQ", "length": 381, "reference_go_mf": ["GO:0008800"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_a885e26892754d7496aa"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_258_1sml_assembly1", "enzyme_name": "beta-lactamase (Class B1)", "ec": ["3.5.2.6"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P52700", "alignment_score": 532.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [22, 288], "sequence": "MRSTLLAFALAVALPAAHTSAAEVPLPQLRAYTVDASWLQPMAPLQIADHTWQIGTEDLTALLVQTPDGAVLLDGGMPQMASHLLDNMKARGVTPRDLRLILLSHAHADHAGPVAELKRRTGAKVAANAESAVLLARGGSDDLHFGDGITYPPANADRIVMDGEVITVGGIVFTAHFMAGHTPGSTAWTWTDTRNGKPVRIAYADSLSAPGYQLQGNPRYPHLIEDYRRSFATVRALPCDVLLTPHPGASNWDYAAGARAGAKALTCKAYADAAEQKFDGQLAKETAGAR", "length": 290, "reference_go_mf": ["GO:0008800", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_ba8be5f44ec7dc12d505"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_259_1n20_assembly1", "enzyme_name": "bornyl diphosphate synthase", "ec": ["5.5.1.8"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "O81192", "alignment_score": 1046.5, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [53, 598], "sequence": "MSIISMNVSILSKPLNCLHNLERRPSKALLVPCTAPTARLRASCSSKLQEAHQIRRSGNYQPALWDSNYIQSLNTPYTEERHLDRKAELIVQVRILLKEKMEPVQQLELIHDLKYLGLSDFFQDEIKEILGVIYNEHKCFHNNEVEKMDLYFTALGFRLLRQHGFNISQDVFNCFKNEKGIDFKASLAQDTKGMLQLYEASFLLRKGEDTLELAREFATKCLQKKLDEGGNEIDENLLLWIRHSLDLPLHWRIQSVEARWFIDAYARRPDMNPLIFELAKLNFNIIQATHQQELKDLSRWWSRLCFPEKLPFVRDRLVESFFWAVGMFEPHQHGYQRKMAATIIVLATVIDDIYDVYGTLDELELFTDTFKRWDTESITRLPYYMQLCYWGVHNYISDAAYDILKEHGFFCLQYLRKSVVDLVEAYFHEAKWYHSGYTPSLDEYLNIAKISVASPAIISPTYFTFANASHDTAVIDSLYQYHDILCLAGIILRLPDDLGTSYFELARGDVPKTIQCYMKETNASEEEAVEHVKFLIREAWKDMNTAIAAGYPFPDGMVAGAANIGRVAQFIYLHGDGFGVQHSKTYEHIAGLLFEPYA", "length": 598, "reference_go_mf": ["GO:0102703", "GO:0047926", "GO:0000287", "GO:0050550", "GO:0042803"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_4933fd9cb1b8695e4632"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_25_1nba_assembly1", "enzyme_name": "N-carbamoylsarcosine amidase", "ec": ["3.5.1.59"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P32400", "alignment_score": 506.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [6, 259], "sequence": "MTETSGTFNDIEARLAAVLEEAFEAGTSIYNERGFKRRIGYGNRPAVIHIDLANAWTQPGHPFSCPGMETIIPNVQRINEAARAKGVPVFYTTNVYRNRDASSGTNDMGLWYSKIPTETLPADSYWAQIDDRIAPADGEVVIEKNRASAFPGTNLELFLTSNRIDTLIVTGATAAGCVRHTVEDAIAKGFRPIIPRETIGDRVPGVVQWNLYDIDNKFGDVESTDSVVQYLDALPQFEDTVPKTLSDPQPEVEAPADPVFAEQH", "length": 264, "reference_go_mf": ["GO:0050127"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_abf7462d31933782a0ae"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_260_1gtk_assembly1", "enzyme_name": "hydroxymethylbilane synthase", "ec": ["2.5.1.61"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P06983", "alignment_score": 574.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [2, 313], "sequence": "MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDSRTRELLAALNHHETALRVTAERAMNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAREILAEVYNGDAPA", "length": 313, "reference_go_mf": ["GO:0004418"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_766ab4f192e9a0cdc7ad"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_261_1di1_assembly1", "enzyme_name": "aristolochene synthase", "ec": ["4.2.3.9"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q03471", "alignment_score": 569.5, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [39, 339], "sequence": "MATSTETISSLAQPFVHLENPINSPLVKETIRPRNDTTITPPPTQWSYLCHPRVKEVQDEVDGYFLENWKFPSFKAVRTFLDAKFSEVTCLYFPLALDDRIHFACRLLTVLFLIDDVLEHMSFADGEAYNNRLIPISRGDVLPDRTKPEEFILYDLWESMRAHDAELANEVLEPTFVFMRAQTDRARLSIHELGHYLEYREKDVGKALLSALMRFSMGLRLSADELQDMKALEANCAKQLSVVNDIYSYDKEEEASRTGHKEGAFLCSAVKVLAEESKLGIPATKRVLWSMTREWETVHDEIVAEKIASPDGCSEAAKAYMKGLEYQMSGNEQWSKTTRRYN", "length": 342, "reference_go_mf": ["GO:0045483"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_67564f725636205d2d1c"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_262_1jfg_assembly1", "enzyme_name": "trichodiene synthase", "ec": ["4.2.3.6"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P13513", "alignment_score": 708.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 354], "sequence": "MENFPTEYFLNTTVRLLEYIRYRDSNYTREERIENLHYAYNKAAHHFAQPRQQQLLKVDPKRLQASLQTIVGMVVYSWAKVSKECMADLSIHYTYTLVLDDSKDDPYPTMVNYFDDLQAGREQAHPWWALVNEHFPNVLRHFGPFCSLNLIRSTLDFFEGCWIEQYNFGGFPGSHDYPQFLRRMNGLGHCVGASLWPKEQFNERSLFLEITSAIAQMENWMVWVNDLMSFYKEFDDERDQISLVKNYVVSDEISLHEALEKLTQDTLHSSKQMVAVFSDKDPQVMDTIECFMHGYVTWHLCDRRYRLSEIYEKVKEEKTEDAQKFCKFYEQAANVGAVSPSEWAYPPVAQLANVRSKDVKEVQKPFLSSIELVE", "length": 374, "reference_go_mf": ["GO:0045482"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_e07b39022512286a54ba"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_263_3kb9_assembly1", "enzyme_name": "epi-isozizaene synthase", "ec": ["4.2.3.37"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q9K499", "alignment_score": 680.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [15, 355], "sequence": "MHAFPHGTTATPTAIAVPPSLRLPVIEAAFPRQLHPYWPKLQETTRTWLLEKRLMPADKVEEYADGLCYTDLMAGYYLGAPDEVLQAIADYSAWFFVWDDRHDRDIVHGRAGAWRRLRGLLHTALDSPGDHLHHEDTLVAGFADSVRRLYAFLPATWNARFARHFHTVIEAYDREFHNRTRGIVPGVEEYLELRRLTFAHWIWTDLLEPSSGCELPDAVRKHPAYRRAALLSQEFAAWYNDLCSLPKEIAGDEVHNLGISLITHHSLTLEEAIGEVRRRVEECITEFLAVERDALRFADELADGTVRGKELSGAVRANVGNMRNWFSSVYWFHHESGRYMVDSWDDRSTPPYVNNEAAGEK", "length": 361, "reference_go_mf": ["GO:0052680", "GO:0010333"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_23f2c12d3195a8b1194e"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_264_1ezf_assembly1", "enzyme_name": "squalene synthase", "ec": ["2.5.1.21"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P37268", "alignment_score": 633.5, "observed_coverage": 0.9969040247678018, "aligned_identity": 1.0, "canonical_span": [38, 370], "sequence": "MEFVKCLGHPEEFYNLVRFRIGGKRKVMPKMDQDSLSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFAKPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVKIRKGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSDPSSSKTRQIISTIRTQNLPNCQLISRSHYSPIYLSFVMLLAALSWQYLTTLSQVTEDYVQTGEH", "length": 417, "reference_go_mf": ["GO:0051996"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_f9537e5da6e5e72a4aba"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_265_5eat_assembly1", "enzyme_name": "5-epi-aristolochene synthase", "ec": ["4.2.3.61"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q40577", "alignment_score": 1043.0, "observed_coverage": 1.0, "aligned_identity": 0.9868421052631579, "canonical_span": [16, 548], "sequence": "MASAAVANYEEEIVRPVADFSPSLWGDQFLSFSIKNQVAEKYAKEIEALKEQTRNMLLATGMKLADTLNLIDTIERLGISYHFEKEIDDILDQIYNQNSNCNDLCTSALQFRLLRQHGFNISPEIFSKFQDENGKFKESLASDVLGLLNLYEASHVRTHADDILEDALAFSTIHLESAAPHLKSPLREQVTHALEQCLHKGVPRVETRFFISSIYDKEQSKNNVLLRFAKLDFNLLQMLHKQELAQVSRWWKDLDFVTTLPYARDRVVECYFWALGVYFEPQYSQARVMLVKTISMISIVDDTFDAYGTVKELEAYTDAIQRWDINEIDRLPDYMKISYKAILDLYKDYEKELSSAGRSHIVCHAIERMKEVVRNYNVESTWFIEGYTPPVSEYLSNALATTTYYYLATTSYLGMKSATEQDFEWLSKNPKILEASVIICRVIDDTATYEVEKSRGQIATGIECCMRDYGISTKEAMAKFQNMAETAWKDINEGLLRPTPVSTEFLTPILNLARIVEVTYIHNLDGYTHPEKVLKPHIINLLVDSIKI", "length": 548, "reference_go_mf": ["GO:0102201", "GO:0102698", "GO:0000287", "GO:0010333"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_a5921d7ac03bfc8425ca"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_266_1apy_assembly1", "enzyme_name": "N4-(beta-N-acetylglucosaminyl)-L-asparaginase", "ec": ["3.5.1.26"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P20933", "alignment_score": 319.0, "observed_coverage": 1.0, "aligned_identity": 0.9937888198757764, "canonical_span": [24, 185], "sequence": "MARKSNLPVLLVPFLLCQALVRCSSPLPLVVNTWPFKNATEAAWRALASGGSALDAVESGCAMCEREQCDGSVGFGGSPDELGETTLDAMIMDGTTMDVGAVGDLRRIKNAIGVARKVLEHTTHTLLVGESATTFAQSMGFINEDLSTTASQALHSDWLARNCQPNYWRNVIPDPSKYCGPYKPPGILKQDIPIHKETEDDRGHDTIGMVVIHKTGHIAAGTSTNGIKFKIHGRVGDSPIPGAGAYADDTAGAAAATGNGDILMRFLPSYQAVEYMRRGEDPTIACQKVISRIQKHFPEFFGAVICANVTGSYGAACNKLSTFTQFSFMVYNSEKNQPTEEKVDCI", "length": 346, "reference_go_mf": ["GO:0003948"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_75fd4db22a15efbf5031"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P20933", "alignment_score": 282.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [205, 346], "sequence": "MARKSNLPVLLVPFLLCQALVRCSSPLPLVVNTWPFKNATEAAWRALASGGSALDAVESGCAMCEREQCDGSVGFGGSPDELGETTLDAMIMDGTTMDVGAVGDLRRIKNAIGVARKVLEHTTHTLLVGESATTFAQSMGFINEDLSTTASQALHSDWLARNCQPNYWRNVIPDPSKYCGPYKPPGILKQDIPIHKETEDDRGHDTIGMVVIHKTGHIAAGTSTNGIKFKIHGRVGDSPIPGAGAYADDTAGAAAATGNGDILMRFLPSYQAVEYMRRGEDPTIACQKVISRIQKHFPEFFGAVICANVTGSYGAACNKLSTFTQFSFMVYNSEKNQPTEEKVDCI", "length": 346, "reference_go_mf": ["GO:0003948"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_75fd4db22a15efbf5031"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_268_1bmt_assembly1", "enzyme_name": "methionine synthase", "ec": ["2.1.1.13"], "controls": [{"chain": "A", "status": "reference_overlength", "selected": {"accession": "P13009", "alignment_score": 492.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [650, 896], "sequence": "MSSKVEQLRAQLNERILVLDGGMGTMIQSYRLNEADFRGERFADWPCDLKGNNDLLVLSKPEVIAAIHNAYFEAGADIIETNTFNSTTIAMADYQMESLSAEINFAAAKLARACADEWTARTPEKPRYVAGVLGPTNRTASISPDVNDPAFRNITFDGLVAAYRESTKALVEGGADLILIETVFDTLNAKAAVFAVKTEFEALGVELPIMISGTITDASGRTLSGQTTEAFYNSLRHAEALTFGLNCALGPDELRQYVQELSRIAECYVTAHPNAGLPNAFGEYDLDADTMAKQIREWAQAGFLNIVGGCCGTTPQHIAAMSRAVEGLAPRKLPEIPVACRLSGLEPLNIGEDSLFVNVGERTNVTGSAKFKRLIKEEKYSEALDVARQQVENGAQIIDINMDEGMLDAEAAMVRFLNLIAGEPDIARVPIMIDSSKWDVIEKGLKCIQGKGIVNSISMKEGVDAFIHHAKLLRRYGAAVVVMAFDEQGQADTRARKIEICRRAYKILTEEVGFPPEDIIFDPNIFAVATGIEEHNNYAQDFIGACEDIKRELPHALISGGVSNVSFSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAGQLAIYDDLPAELRDAVEDVILNRRDDGTERLLELAEKYRGSKTDDTANAQQAEWRSWEVNKRLEYSLVKGITEFIEQDTEEARQQATRPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKQAVAYLEPFIEASKEQGKTNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIVDLGVMVPAEKILRTAKEVNADLIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKAHTAVKIEQNYSGPTVYVQNASRTVGVVAALLSDTQRDDFVARTRKEYETVRIQHGRKKPRTPPVTLEAARDNDFAFDWQAYTPPVAHRLGVQEVEASIETLRNYIDWTPFFMTWSLAGKYPRILEDEVVGVEAQRLFKDANDMLDKLSAEKTLNPRGVVGLFPANRVGDDIEIYRDETRTHVINVSHHLRQQTEKTGFANYCLADFVAPKLSGKADYIGAFAVTGGLEEDALADAFEAQHDDYNKIMVKALADRLAEAFAEYLHERVRKVYWGYAPNENLSNEELIRENYQGIRPAPGYPACPEHTEKATIWELLEVEKHTGMKLTESFAMWPGASVSGWYFSHPDSKYYAVAQIQRDQVEDYARRKGMSVTEVERWLAPNLGYDAD", "length": 1227, "reference_go_mf": ["GO:0031419", "GO:0008705", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_269_3dgb_assembly2", "enzyme_name": "muconate cycloisomerase (syn)", "ec": ["5.5.1.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q4K9X1", "alignment_score": 742.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 372], "sequence": "MHASAIESIETIIVDLPTIRPHKLAMHTMQNQTLVLIRLRCADGIEGLGESTTIGGLAYGNESPDSIKTNIDRFVAPLLIGQDASNINAAMLRLEQSIRGNTFAKSGIESALLDAQGKRLGLPVSELLGGRVRDALPVAWTLASGDTAKDIAEAQKMLDLRRHRIFKLKIGAGEVDRDLAHVIAIKKALGDSASVRVDVNQAWDEAVALRACRILGGNGIDLIEQPISRNNRAGMVRLNASSPAPIMADESIECVEDAFNLAREGAASVFALKIAKNGGPRATLRTAAIAEAAGIGLYGGTMLEGGIGTLASAHAFLTLNKLSWDTELFGPLLLTEDILAEPPVYRDFHLHVSKAPGLGLSLDEERLAFFRRDKTTPVLHHT", "length": 382, "reference_go_mf": ["GO:0018850", "GO:0030145", "GO:0018849"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_f6440fafa13eb2863ac9"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_26_1ptd_assembly1", "enzyme_name": "phosphatidylinositol diacylglycerol-lyase", "ec": ["4.6.1.13"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P14262", "alignment_score": 592.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [31, 327], "sequence": "MSNKKLILKLFICSTIFITFVFALHDKRVVAASSVNELENWSKWMQPIPDSIPLARISIPGTHDSGTFKLQNPIKQVWGMTQEYDFRYQMDHGARIFDIRGRLTDDNTIVLHHGPLYLYVTLHEFINEAKQFLKDNPSETIIMSLKKEYEDMKGAEDSFSSTFEKKYFVDPIFLKTEGNIKLGDARGKIVLLKRYSGSNEPGGYNNFYWPDNETFTTTVNQNANVTVQDKYKVSYDEKVKSIKDTMDETMNNSEDLNHLYINFTSLSSGGTAWNSPYYYASYINPEIANYIKQKNPARVGWVIQDYINEKWSPLLYQEVIRANKSLIKE", "length": 329, "reference_go_mf": ["GO:0004436", "GO:0008081"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_f6a48bdc8cfab76c60e6"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_270_1h1z_assembly1", "enzyme_name": "ribulose-phosphate 3-epimerase (cytoplasmic)", "ec": ["5.1.3.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q9SE42", "alignment_score": 438.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [5, 224], "sequence": "MAAAAAAKIAPSMLSSDFANLAAEADRMVRLGADWLHMDIMDGHFVPNLTIGAPVIQSLRKHTKAYLDCHLMVTNPSDYVEPLAKAGASGFTFHIEVSRDNWQELIQSIKAKGMRPGVSLRPGTPVEEVFPLVEAENPVELVLVMTVEPGFGGQKFMPEMMEKVRALRKKYPSLDIEVDGGLGPSTIDVAASAGANCIVAGSSIFGAAEPGEVISALRKSVEGSQNKS", "length": 228, "reference_go_mf": ["GO:0004750", "GO:0046872"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_4b9a2f9723eb621e2b3f"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_271_1pym_assembly1", "enzyme_name": "phosphoenolpyruvate mutase", "ec": ["5.4.2.9"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P56839", "alignment_score": 526.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [4, 295], "sequence": "MSTKVKKTTQLKQMLNSKDLEFIMEAHNGLSARIVQEAGFKGIWGSGLSVSAQLGVRDSNEASWTQVVEVLEFMSDASDVPILLDADTGYGNFNNARRLVRKLEDRGVAGACLEDKLFPKTNSLHDGRAQPLADIEEFALKIKACKDSQTDPDFCIVARVEAFIAGWGLDEALKRAEAYRNAGADAILMHSKKADPSDIEAFMKAWNNQGPVVIVPTKYYKTPTDHFRDMGVSMVIWANHNLRASVSAIQQTTKQIYDDQSLVNVEDKIVSVKEIFRLQRDDELVQAEDKYLPKN", "length": 295, "reference_go_mf": ["GO:0050188"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_5312d4f425ef0dc94c0a"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_272_1f61_assembly1", "enzyme_name": "isocitrate lyase", "ec": ["4.1.3.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P9WKK7", "alignment_score": 834.0, "observed_coverage": 0.9976076555023924, "aligned_identity": 1.0, "canonical_span": [1, 418], "sequence": "MSVVGTPKSAEQIQQEWDTNPRWKDVTRTYSAEDVVALQGSVVEEHTLARRGAEVLWEQLHDLEWVNALGALTGNMAVQQVRAGLKAIYLSGWQVAGDANLSGHTYPDQSLYPANSVPQVVRRINNALQRADQIAKIEGDTSVENWLAPIVADGEAGFGGALNVYELQKALIAAGVAGSHWEDQLASEKKCGHLGGKVLIPTQQHIRTLTSARLAADVADVPTVVIARTDAEAATLITSDVDERDQPFITGERTREGFYRTKNGIEPCIARAKAYAPFADLIWMETGTPDLEAARQFSEAVKAEYPDQMLAYNCSPSFNWKKHLDDATIAKFQKELAAMGFKFQFITLAGFHALNYSMFDLAYGYAQNQMSAYVELQEREFAAEERGYTATKHQREVGAGYFDRIATTVDPNSSTTALTGSTEEGQFH", "length": 428, "reference_go_mf": ["GO:0004451", "GO:0046421", "GO:0035375"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_d2fc45ff347238e2b687"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_274_1pow_assembly1", "enzyme_name": "pyruvate oxidase", "ec": ["1.2.3.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P37063", "alignment_score": 1167.0, "observed_coverage": 1.0, "aligned_identity": 0.9982905982905983, "canonical_span": [8, 593], "sequence": "MVMKQTKQTNILAGAAVIKVLEAWGVDHLYGIPGGSINSIMDALSAERDRIHYIQVRHEEVGAMAAAADAKLTGKIGVCFGSAGPGGTHLMNGLYDAREDHVPVLALIGQFGTTGMNMDTFQEMNENPIYADVADYNVTAVNAATLPHVIDEAIRRAYAHQGVAVVQIPVDLPWQQIPAEDWYASANSYQTPLLPEPDVQAVTRLTQTLLAAERPLIYYGIGARKAGKELEQLSKTLKIPLMSTYPAKGIVADRYPAYLGSANRVAQKPANEALAQADVVLFVGNNYPFAEVSKAFKNTRYFLQIDIDPAKLGKRHKTDIAVLADAQKTLAAILAQVSERESTPWWQANLANVKNWRAYLASLEDKQEGPLQAYQVLRAVNKIAEPDAIYSIDVGDINLNANRHLKLTPSNRHITSNLFATMGVGIPGAIAAKLNYPERQVFNLAGDGGASMTMQDLATQVQYHLPVINVVFTNCQYGFIKDEQEDTNQNDFIGVEFNDIDFSKIADGVHMQAFRVNKIEQLPDVFEQAKAIAQHEPVLIDAVITGDRPLPAEKLRLDSATSSAADIEAFKQRYEAQDLQPLSTYLKQFGLDDLQHQIGQGGF", "length": 603, "reference_go_mf": ["GO:0000287", "GO:0047112", "GO:0030976"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_848c780f47b676509e9e"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P37063", "alignment_score": 1167.0, "observed_coverage": 1.0, "aligned_identity": 0.9982905982905983, "canonical_span": [8, 593], "sequence": "MVMKQTKQTNILAGAAVIKVLEAWGVDHLYGIPGGSINSIMDALSAERDRIHYIQVRHEEVGAMAAAADAKLTGKIGVCFGSAGPGGTHLMNGLYDAREDHVPVLALIGQFGTTGMNMDTFQEMNENPIYADVADYNVTAVNAATLPHVIDEAIRRAYAHQGVAVVQIPVDLPWQQIPAEDWYASANSYQTPLLPEPDVQAVTRLTQTLLAAERPLIYYGIGARKAGKELEQLSKTLKIPLMSTYPAKGIVADRYPAYLGSANRVAQKPANEALAQADVVLFVGNNYPFAEVSKAFKNTRYFLQIDIDPAKLGKRHKTDIAVLADAQKTLAAILAQVSERESTPWWQANLANVKNWRAYLASLEDKQEGPLQAYQVLRAVNKIAEPDAIYSIDVGDINLNANRHLKLTPSNRHITSNLFATMGVGIPGAIAAKLNYPERQVFNLAGDGGASMTMQDLATQVQYHLPVINVVFTNCQYGFIKDEQEDTNQNDFIGVEFNDIDFSKIADGVHMQAFRVNKIEQLPDVFEQAKAIAQHEPVLIDAVITGDRPLPAEKLRLDSATSSAADIEAFKQRYEAQDLQPLSTYLKQFGLDDLQHQIGQGGF", "length": 603, "reference_go_mf": ["GO:0000287", "GO:0047112", "GO:0030976"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_848c780f47b676509e9e"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_275_3ey9_assembly1", "enzyme_name": "pyruvate dehydrogenase (cytochrome)", "ec": ["1.2.5.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P07003", "alignment_score": 1142.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 572], "sequence": "MKQTVAAYIAKTLESAGVKRIWGVTGDSLNGLSDSLNRMGTIEWMSTRHEEVAAFAAGAEAQLSGELAVCAGSCGPGNLHLINGLFDCHRNHVPVLAIAAHIPSSEIGSGYFQETHPQELFRECSHYCELVSSPEQIPQVLAIAMRKAVLNRGVSVVVLPGDVALKPAPEGATMHWYHAPQPVVTPEEEELRKLAQLLRYSSNIALMCGSGCAGAHKELVEFAGKIKAPIVHALRGKEHVEYDNPYDVGMTGLIGFSSGFHTMMNADTLVLLGTQFPYRAFYPTDAKIIQIDINPASIGAHSKVDMALVGDIKSTLRALLPLVEEKADRKFLDKALEDYRDARKGLDDLAKPSEKAIHPQYLAQQISHFAADDAIFTCDVGTPTVWAARYLKMNGKRRLLGSFNHGSMANAMPQALGAQATEPERQVVAMCGDGGFSMLMGDFLSVVQMKLPVKIVVFNNSVLGFVAMEMKAGGYLTDGTELHDTNFARIAEACGITGIRVEKASEVDEALQRAFSIDGPVLVDVVVAKEELAIPPQIKLEQAKGFSLYMLRAIISGRGDEVIELAKTNWLR", "length": 572, "reference_go_mf": ["GO:0050660", "GO:0042802", "GO:0008289", "GO:0000287", "GO:0052737", "GO:0030976", "GO:0048039"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_b78a9a35c32c713efed9"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P07003", "alignment_score": 1142.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 572], "sequence": "MKQTVAAYIAKTLESAGVKRIWGVTGDSLNGLSDSLNRMGTIEWMSTRHEEVAAFAAGAEAQLSGELAVCAGSCGPGNLHLINGLFDCHRNHVPVLAIAAHIPSSEIGSGYFQETHPQELFRECSHYCELVSSPEQIPQVLAIAMRKAVLNRGVSVVVLPGDVALKPAPEGATMHWYHAPQPVVTPEEEELRKLAQLLRYSSNIALMCGSGCAGAHKELVEFAGKIKAPIVHALRGKEHVEYDNPYDVGMTGLIGFSSGFHTMMNADTLVLLGTQFPYRAFYPTDAKIIQIDINPASIGAHSKVDMALVGDIKSTLRALLPLVEEKADRKFLDKALEDYRDARKGLDDLAKPSEKAIHPQYLAQQISHFAADDAIFTCDVGTPTVWAARYLKMNGKRRLLGSFNHGSMANAMPQALGAQATEPERQVVAMCGDGGFSMLMGDFLSVVQMKLPVKIVVFNNSVLGFVAMEMKAGGYLTDGTELHDTNFARIAEACGITGIRVEKASEVDEALQRAFSIDGPVLVDVVVAKEELAIPPQIKLEQAKGFSLYMLRAIISGRGDEVIELAKTNWLR", "length": 572, "reference_go_mf": ["GO:0050660", "GO:0042802", "GO:0008289", "GO:0000287", "GO:0052737", "GO:0030976", "GO:0048039"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_b78a9a35c32c713efed9"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_276_1ogy_assembly3", "enzyme_name": "nitrate reductase", "ec": ["1.7.99.4"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q53176", "alignment_score": 1545.0, "observed_coverage": 1.0, "aligned_identity": 0.9860583016476553, "canonical_span": [40, 829], "sequence": "MTLTRRDLIKAQAAATAAAAAGLPVSALAQPVTGGAEALRIRWSKAPCRFCGTGCGVMVGTRDGQVVATHGDTQAEVNRGLNCVKGYFLSKIMYGEDRLTTPLLRMKDGVYHKEGEFAPVSWDEAFDVMAAQAKRVLKEKGPKAVGMFGSGQWTIWEGYAASKLMRAGFRSNNLDPNARHCMASAATAFMRTFGMDEPMGCYDDFEAADAFVLWGSNMAEMHPILWSRLTDRRLSHEHVRVAVLSTFTHRSMDLADTPIIFRPGTDLAILNYIAHHIISTGRVNRDFVDRHTNFALGATDIGYGLRPEHQLQLAAKGAADAGAMTPTDFETFAALVSEYTLEKAAEISGVEPALLEELAELYADPDRKVMSLWTMGFNQHVRGVWANHMVYNLHLLTGKISEPGNSPFSLTGQPSACGTAREVGTFAHRLPADMVVTNPEHRAHAEEIWKLPAGLLPDWVGAHAVEQDRKLHDGEINFYWVQVNNNMQAAPNIDQETYPGYRNPENFIVVSDAYPTVTGRCADLVLPAAMWVEKEGAYGNAERRTHFWHQLVEAPGEARSDLWQLMEFSKRFTTDEVWPEEILSAAPAYRGKTLFEVLFANGSVDRFPASDVNPDHANHEAALFGFYPQKGLFEEYAAFGRGHGHDLAPFDTYHEVRGLRWPVVEGEETRWRYREGFDPYVKPGEGLRFYGKPDGRAVILGVPYEPPAESPDEEFGFWLVTGRVLEHWHSGSMTLRVPELYKAFPGAVCFMHPEDARSRGLNRGSEVRVISRRGEIRTRLETRGRNRMPRGVVFVPWFDASQLINKVTLDANDPISRQTDFKKCAVKIEAV", "length": 831, "reference_go_mf": ["GO:0051539", "GO:0009055", "GO:0005506", "GO:0030151", "GO:0043546", "GO:0050140"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_887f1fe3879fe2a7189c"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_278_2b3i_assembly1", "enzyme_name": "plastoquinol-plastocyanin reductase", "ec": ["7.1.1.6"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P50057", "alignment_score": 191.0, "observed_coverage": 1.0, "aligned_identity": 0.9896907216494846, "canonical_span": [34, 131], "sequence": "MKFFASLSKRFAPVLSLVVLVAGTLLLSAAPASAATVQIKMGTDKYAPLYEPKALSISAGDTVEFVMNKVGPHNVIFDKVPAGESAPALSNTKLAIAPGSFYSVTLGTPGTYSFYCTPHRGAGMVGTITVE", "length": 131, "reference_go_mf": ["GO:0005507", "GO:0009055"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_b39446d19147213245a1"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_27_1ah7_assembly1", "enzyme_name": "phospholipase C", "ec": ["3.1.4.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P09598", "alignment_score": 490.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [38, 283], "sequence": "MKKKVLALAAAITVVAPLQSVAFAHENDGGSKIKIVHRWSAEDKHKEGVNSHLWIVNRAIDIMSRNTTLVKQDRVAQLNEWRTELENGIYAADYENPYYDNSTFASHFYDPDNGKTYIPFAKQAKETGAKYFKLAGESYKNKDMKQAFFYLGLSLHYLGDVNQPMHAANFTNLSYPQGFHSKYENFVDTIKDNYKVTDGNGYWNWKGTNPEEWIHGAAVVAKQDYSGIVNDNTKDWFVKAAVSQEYADKWRAEVTPMTGKRLMDAQRVTAGYIQLWFDTYGDR", "length": 283, "reference_go_mf": ["GO:0034480", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_53f7304997f7a7fe79c7"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_280_1dtw_assembly1", "enzyme_name": "3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)", "ec": ["1.2.4.4"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P12694", "alignment_score": 752.5, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [51, 445], "sequence": "MAVAIAAARVWRLNRGLSQAALLLLRQPGARGLARSHPPRQQQQFSSLDDKPQFPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYKSMTLLNTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLELFMAQCYGNISDLGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRANANRVVICYFGEGAASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAARGPGYGIMSIRVDGNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDHPISRLRHYLLSQGWWDEEQEKAWRKQSRRKVMEAFEQAERKPKPNPNLLFSDVYQEMPAQLRKQQESLARHLQTYGEHYPLDHFDK", "length": 445, "reference_go_mf": ["GO:0003863", "GO:0016831"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_90e0c4640fea1a9c8e6e"}, "alternative_alignments": [{"accession": "P21953", "alignment_score": 8.0, "observed_coverage": 0.010471204188481676, "aligned_identity": 1.0, "canonical_span": [79, 83], "length": 392, "reference_go_mf": ["GO:0003863"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}, {"chain": "B", "status": "assigned", "selected": {"accession": "P21953", "alignment_score": 652.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [66, 392], "sequence": "MAVVAAAAGWLLRLRAAGAEGHWRRLPGAGLARGFLHPAATVEDAAQRRQVAHFTFQPDPEPREYGQTQKMNLFQSVTSALDNSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEPKILYRAAAEEVPIEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVSCEVIDLRTIIPWDVDTICKSVIKTGRLLISHEAPLTGGFASEISSTVQEECFLNLEAPISRVCGYDTPFPHIFEPFYIPDKWKCYDALRKMINY", "length": 392, "reference_go_mf": ["GO:0003863"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_f5cb3b8e0e3b02ef9019"}, "alternative_alignments": [{"accession": "P12694", "alignment_score": 8.0, "observed_coverage": 0.012269938650306749, "aligned_identity": 1.0, "canonical_span": [146, 150], "length": 445, "reference_go_mf": ["GO:0003863", "GO:0016831"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_281_2gmh_assembly1", "enzyme_name": "electron-transferring-flavoprotein dehydrogenase", "ec": ["1.5.5.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P55931", "alignment_score": 1156.0, "observed_coverage": 1.0, "aligned_identity": 0.9965576592082617, "canonical_span": [36, 617], "sequence": "MMVPLAKLASPAYQCFHALKIKKNYLPLCATRWSSTCKVPRITTHYTIYPRDQDKRWEGVNMERFAEEADVVIVGAGPAGLSAATRLKQLAAQHEKDLRVCLVEKAAQIGAHTLSGACLDPRAFEELFPDWKEKGAPLNTPVTEDRFGILTEKYRIPVPILPGLPMNNHGNYVVRLGHLVSWMGEQAEALGVEVYPGYAAAEILFHEDGSVKGIATNDVGIQKDGAPKTTFERGLELHAKVTIFAEGCHGHLAKQLYKKFDLRANCEPQTYGIGLKELWVIDEKKWKPGRVDHTVGWPLDRHTYGGSFLYHLNEGEPLLALGFVVGLDYQNPYLSPFREFQRWKHHPSIKPTLEGGKRIAYGARALNEGGFQSIPKLTFPGGLLIGCSPGFMNVPKIKGTHTAMKSGILAAESIFNQLTSENLQSKTIGLHVTEYEDNLKNSWVWKELYSVRNIRPSCHGILGVYGGMIYTGIFYWIFRGMEPWTLKHKGSDSDQLKPAKDCTPIEYPKPDGQISFDLLSSVALSGTNHEHDQPAHLTLKDDSVPVNRNLSIYDGPEQRFCPAGVYEFVPLEQGDGFRLQINAQNCVHCKTCDIKDPSQNINWVVPEGGGGPAYNGM", "length": 617, "reference_go_mf": ["GO:0051539", "GO:0009055", "GO:0004174", "GO:0050660", "GO:0051536", "GO:0016491", "GO:0048039"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_3f51aef8845c7fdfb4d0"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_285_1uok_assembly1", "enzyme_name": "oligo-1,6-glucosidase", "ec": ["3.2.1.10"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P21332", "alignment_score": 1116.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 558], "sequence": "MEKQWWKESVVYQIYPRSFMDSNGDGIGDLRGIISKLDYLKELGIDVIWLSPVYESPNDDNGYDISDYCKIMNEFGTMEDWDELLHEMHERNMKLMMDLVVNHTSDEHNWFIESRKSKDNKYRDYYIWRPGKEGKEPNNWGAAFSGSAWQYDEMTDEYYLHLFSKKQPDLNWDNEKVRQDVYEMMKFWLEKGIDGFRMDVINFISKEEGLPTVETEEEGYVSGHKHFMNGPNIHKYLHEMNEEVLSHYDIMTVGEMPGVTTEEAKLYTGEERKELQMVFQFEHMDLDSGEGGKWDVKPCSLLTLKENLTKWQKALEHTGWNSLYWNNHDQPRVVSRFGNDGMYRIESAKMLATVLHMMKGTPYIYQGEEIGMTNVRFESIDEYRDIETLNMYKEKVMERGEDIEKVMQSIYIKGRDNARTPMQWDDQNHAGFTTGEPWITVNPNYKEINVKQAIQNKDSIFYYYKKLIELRKNNEIVVYGSYDLILENNPSIFAYVRTYGVEKLLVIANFTAEECIFELPEDISYSEVELLIHNYDVENGPIENITLRPYEAMVFKLK", "length": 558, "reference_go_mf": ["GO:0004556", "GO:0004574"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_320cd9ef98faa5031cf9"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_286_2z67_assembly1", "enzyme_name": "O-phospho-L-seryl-tRNASec:L-selenocysteinyl-tRNA synthase", "ec": ["2.9.1.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q6LZM9", "alignment_score": 802.0, "observed_coverage": 1.0, "aligned_identity": 0.9976415094339622, "canonical_span": [1, 434], "sequence": "MLDFNIEGLIPKNMEKRGELVLNEYLKEIEDVFNHRKIPENGIDDEKIKLFLKFLSMMDTDKDPKSVRIGEREARTYSKIHEELSSGFCHGIGRSGNLVDPQPKASGASIMYALTNKILESFFKQLGLNVHAIATPISTGMSISLCLSAARKKYGSNVVIYPYASHKSPIKAVSFVGMNMRLVETVLDGDRVYVPVEDIENAIKKEIELGNRPCVLSTLTFFPPRNSDDIVEIAKICENYDIPHIINGAYAIQNNYYLEKLKKAFKYRVDAVVSSSDKNLLTPIGGGLVYSTDAEFIKEISLSYPGRASATPVVNTLVSLLSMGSKNYLELVKNQKNSKKLLDELLNDLSKKTGGKFLDVESPIASCISVNSDPVEIAAKLYNLRVTGPRGIKKTDHFGNCYLGTYTHDYIVMNAAIGVRTEDIVNSVSKLEKILL", "length": 436, "reference_go_mf": ["GO:0098621", "GO:0000049"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_7ecef8fcab9102b9f230"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "Q6LZM9", "alignment_score": 802.0, "observed_coverage": 1.0, "aligned_identity": 0.9976415094339622, "canonical_span": [1, 434], "sequence": "MLDFNIEGLIPKNMEKRGELVLNEYLKEIEDVFNHRKIPENGIDDEKIKLFLKFLSMMDTDKDPKSVRIGEREARTYSKIHEELSSGFCHGIGRSGNLVDPQPKASGASIMYALTNKILESFFKQLGLNVHAIATPISTGMSISLCLSAARKKYGSNVVIYPYASHKSPIKAVSFVGMNMRLVETVLDGDRVYVPVEDIENAIKKEIELGNRPCVLSTLTFFPPRNSDDIVEIAKICENYDIPHIINGAYAIQNNYYLEKLKKAFKYRVDAVVSSSDKNLLTPIGGGLVYSTDAEFIKEISLSYPGRASATPVVNTLVSLLSMGSKNYLELVKNQKNSKKLLDELLNDLSKKTGGKFLDVESPIASCISVNSDPVEIAAKLYNLRVTGPRGIKKTDHFGNCYLGTYTHDYIVMNAAIGVRTEDIVNSVSKLEKILL", "length": 436, "reference_go_mf": ["GO:0098621", "GO:0000049"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_7ecef8fcab9102b9f230"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_287_1g8f_assembly1", "enzyme_name": "sulfate adenylyltransferase", "ec": ["2.7.7.4"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P08536", "alignment_score": 1014.0, "observed_coverage": 1.0, "aligned_identity": 0.996078431372549, "canonical_span": [1, 511], "sequence": "MPAPHGGILQDLIARDALKKNELLSEAQSSDILVWNLTPRQLCDIELILNGGFSPLTGFLNENDYSSVVTDSRLADGTLWTIPITLDVDEAFANQIKPDTRIALFQDDEIPIAILTVQDVYKPNKTIEAEKVFRGDPEHPAISYLFNVAGDYYVGGSLEAIQLPQHYDYPGLRKTPAQLRLEFQSRQWDRVVAFQTRNPMHRAHRELTVRAAREANAKVLIHPVVGLTKPGDIDHHTRVRVYQEIIKRYPNGIAFLSLLPLAMRMSGDREAVWHAIIRKNYGASHFIVGRDHAGPGKNSKGVDFYGPYDAQELVESYKHELDIEVVPFRMVTYLPDEDRYAPIDQIDTTKTRTLNISGTELRRRLRVGGEIPEWFSYPEVVKILRESNPPRPKQGFSIVLGNSLTVSREQLSIALLSTFLQFGGGRYYKIFEHNNKTELLSLIQDFIGSGSGLIIPNQWEDDKDSVVGKQNVYLLDTSSSADIQLESADEPISHIVQKVVLFLEDNGFFVF", "length": 511, "reference_go_mf": ["GO:0004781"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_ca1e9056f181433afaae"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_288_3s8r_assembly1", "enzyme_name": "glutaryl-7-aminocephalosporanic-acid acylase", "ec": ["3.5.1.93"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P07662", "alignment_score": 1362.0, "observed_coverage": 1.0, "aligned_identity": 0.9970760233918129, "canonical_span": [34, 718], "sequence": "MLRVLHRAASALVMATVIGLAPAVAFALAEPTSTPQAPIAAYKPRSNEILWDGYGVPHIYGVDAPSAFYGYGWAQARSHGDNILRLYGEARGKGAEYWGPDYEQTTVWLLTNGVPERAQQWYAQQSPDFRANLDAFAAGINAYAQQNPDDISPEVRQVLPVSGADVVAHAHRLMNFLYVASPGRTLGEGDPPDLADQGSNSWAVAPGKTANGNALLLQNPHLSWTTDYFTYYEAHLVTPDFEIYGATQIGLPVIRFAFNQRMGITNTVNGMVGATNYRLTLQDGGYLYDGQVRPFERPQASYRLRQADGTTVDKPLEIRSSVHGPVFERADGTAVAVRVAGLDRPGMLEQYFDMITADSFDDYEAALARMQVPTFNIVYADREGTINYSFNGVAPKRAEGDIAFWQGLVPGDSSRYLWTETHPLDDLPRVTNPPGGFVQNSNDPPWTPTWPVTYTPKDFPSYLAPQTPHSLRAQQSVRLMSENDDLTLERFMALQLSHRAVMADRTLPDLIPAALIDPDPEVQAAARLLAAWDREFTSDSRAALLFEEWARLFAGQNFAGQAGFATPWSLDKPVSTPYGVRDPKAAVDQLRTAIANTKRKYGAIDRPFGDASRMILNDVNVPGAAGYGNLGSFRVFTWSDPDENGVRTPVHGETWVAMIEFSTPVRAYGLMSYGNSRQPGTTHYSDQIERVSRADFRELLLRREQVEAAVQERTPFNFKP", "length": 720, "reference_go_mf": ["GO:0033968"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_186cb5dbe88e91d55ada"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_289_1n0h_assembly1", "enzyme_name": "acetolactate synthase (biosynthetic)", "ec": ["2.2.1.6"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P07342", "alignment_score": 1189.5, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [82, 687], "sequence": "MIRQSTLKNFAIKRCFQHIAYRNTPAMRSVALAQRFYSSSSRYYSASPLPASKRPEPAPSFNVDPLEQPAEPSKLAKKLRAEPDMDTSFVGLTGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEADVVGISRSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTKTTLPSNALNQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQIPVTTTLQGLGSFDQEDPKSLDMLGMHGCATANLAVQNADLIIAVGARFDDRVTGNISKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVKERSEWFAQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQMWAAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSAVQAGTPVKILILNNEEQGMVTQWQSLFYEHRYSHTHQLNPDFIKLAEAMGLKGLRVKKQEELDAKLKEFVSTKGPVLLEVEVDKKVPVLPMVAGGSGLDEFINFDPEVERQQTELRHKRTGGKH", "length": 687, "reference_go_mf": ["GO:0003984", "GO:0050660", "GO:0000287", "GO:0030976"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_ab9b465ac089193dee02"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P07342", "alignment_score": 1187.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [82, 687], "sequence": "MIRQSTLKNFAIKRCFQHIAYRNTPAMRSVALAQRFYSSSSRYYSASPLPASKRPEPAPSFNVDPLEQPAEPSKLAKKLRAEPDMDTSFVGLTGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEADVVGISRSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTKTTLPSNALNQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQIPVTTTLQGLGSFDQEDPKSLDMLGMHGCATANLAVQNADLIIAVGARFDDRVTGNISKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVKERSEWFAQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQMWAAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSAVQAGTPVKILILNNEEQGMVTQWQSLFYEHRYSHTHQLNPDFIKLAEAMGLKGLRVKKQEELDAKLKEFVSTKGPVLLEVEVDKKVPVLPMVAGGSGLDEFINFDPEVERQQTELRHKRTGGKH", "length": 687, "reference_go_mf": ["GO:0003984", "GO:0050660", "GO:0000287", "GO:0030976"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_ab9b465ac089193dee02"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_28_1djx_assembly1", "enzyme_name": "phosphoinositide phospholipase C", "ec": ["3.1.4.11"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P10688", "alignment_score": 998.5, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [199, 756], "sequence": "MDSGRDFLTLHGLQDDPDLQALLKGSQLLKVKSSSWRRERFYKLQEDCKTIWQESRKVMRSPESQLFSIEDIQEVRMGHRTEGLEKFARDIPEDRCFSIVFKDQRNTLDLIAPSPADAQHWVQGLRKIIHHSGSMDQRQKLQHWIHSCLRKADKNKDNKMNFKELKDFLKELNIQVDDGYARKIFRECDHSQTDSLEDEEIETFYKMLTQRAEIDRAFEEAAGSAETLSVERLVTFLQHQQREEEAGPALALSLIERYEPSETAKAQRQMTKDGFLMYLLSADGNAFSLAHRRVYQDMDQPLSHYLVSSSHNTYLLEDQLTGPSSTEAYIRALCKGCRCLELDCWDGPNQEPIIYHGYTFTSKILFCDVLRAIRDYAFKASPYPVILSLENHCSLEQQRVMARHLRAILGPILLDQPLDGVTTSLPSPEQLKGKILLKGKKLGGLLPAGGENGSEATDVSDEVEAAEMEDEAVRSQVQHKPKEDKLKLVPELSDMIIYCKSVHFGGFSSPGTSGQAFYEMASFSESRALRLLQESGNGFVRHNVSCLSRIYPAGWRTDSSNYSPVEMWNGGCQIVALNFQTPGPEMDVYLGCFQDNGGCGYVLKPAFLRDPNTTFNSRALTQGPWWRPERLRVRIISGQQLPKVNKNKNSIVDPKVIVEIHGVGRDTGSRQTAVITNNGFNPRWDMEFEFEVTVPDLALVRFMVEDYDSSSKNDFIGQSTIPWNSLKQGYRHVHLLSKNGDQHPSATLFVKISIQD", "length": 756, "reference_go_mf": ["GO:0004629", "GO:0005509", "GO:0005544", "GO:0019899", "GO:0032794", "GO:0070679", "GO:0070300", "GO:1901981", "GO:0120548", "GO:0004439", "GO:0005546", "GO:0004435", "GO:0005543"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_57c29936bc5735d460fc"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_290_1zio_assembly1", "enzyme_name": "adenylate kinase", "ec": ["2.7.4.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P27142", "alignment_score": 434.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 217], "sequence": "MNLVLMGLPGAGKGTQAEKIVAAYGIPHISTGDMFRAAMKEGTPLGLQAKQYMDRGDLVPDEVTIGIVRERLSKDDCQNGFLLDGFPRTVAQAEALETMLADIGRKLDYVIHIDVRQDVLMERLTGRRICRNCGATYHLIFHPPAKPGVCDKCGGELYQRADDNEATVANRLEVNMKQMKPLVDFYEQKGYLRNINGEQDMEKVFADIRELLGGLAR", "length": 217, "reference_go_mf": ["GO:0004017", "GO:0005524", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_bac69ee5fb03134f1541"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_291_1mla_assembly1", "enzyme_name": "malonyl-CoA-acyl carrier protein transacylase", "ec": ["2.3.1.39"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0AAI9", "alignment_score": 610.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [2, 307], "sequence": "MTQFAFVFPGQGSQTVGMLADMAASYPIVEETFAEASAALGYDLWALTQQGPAEELNKTWQTQPALLTASVALYRVWQQQGGKAPAMMAGHSLGEYSALVCAGVIDFADAVRLVEMRGKFMQEAVPEGTGAMAAIIGLDDASIAKACEEAAEGQVVSPVNFNSPGQVVIAGHKEAVERAGAACKAAGAKRALPLPVSVPSHCALMKPAADKLAVELAKITFNAPTVPVVNNVDVKCETNGDAIRDALVRQLYNPVQWTKSVEYMAAQGVEHLYEVGPGKVLTGLTKRIVDTLTASALNEPSAMAAALEL", "length": 309, "reference_go_mf": ["GO:0004314"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_1d1263f4d793f3d3482d"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_292_1dd8_assembly1", "enzyme_name": "beta-ketoacyl-[acyl carrier protein] synthase I", "ec": ["2.3.1.41"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0A953", "alignment_score": 809.0, "observed_coverage": 1.0, "aligned_identity": 0.9975369458128078, "canonical_span": [0, 406], "sequence": "MKRAVITGLGIVSSIGNNQQEVLASLREGRSGITFSQELKDSGMRSHVWGNVKLDTTGLIDRKVVRFMSDASIYAFLSMEQAIADAGLSPEAYQNNPRVGLIAGSGGGSPRFQVFGADAMRGPRGLKAVGPYVVTKAMASGVSACLATPFKIHGVNYSISSACATSAHCIGNAVEQIQLGKQDIVFAGGGEELCWEMACEFDAMGALSTKYNDTPEKASRTYDAHRDGFVIAGGGGMVVVEELEHALARGAHIYAEIVGYGATSDGADMVAPSGEGAVRCMKMAMHGVDTPIDYLNSHGTSTPVGDVKELAAIREVFGDKSPAISATKAMTGHSLGAAGVQEAIYSLLMLEHGFIAPSINIEELDEQAAGLNIVTETTDRELTTVMSNSFGFGGTNATLVMRKLKD", "length": 406, "reference_go_mf": ["GO:0004315"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_f3506f7e41210cb700cf"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_293_1mht_assembly1", "enzyme_name": "DNA (cytosine-5-)-methyltransferase (HhaI)", "ec": ["2.1.1.37"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P05102", "alignment_score": 654.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 327], "sequence": "MIEIKDKQLTGLRFIDLFAGLGGFRLALESCGAECVYSNEWDKYAQEVYEMNFGEKPEGDITQVNEKTIPDHDILCAGFPCQAFSISGKQKGFEDSRGTLFFDIARIVREKKPKVVFMENVKNFASHDNGNTLEVVKNTMNELDYSFHAKVLNALDYGIPQKRERIYMICFRNDLNIQNFQFPKPFELNTFVKDLLLPDSEVEHLVIDRKDLVMTNQEIEQTTPKTVRLGIVGKGGQGERIYSTRGIAITLSAYGGGIFAKTGGYLVNGKTRKLHPRECARVMGYPDSYKVHPSTSQAYKQFGNSVVINVLQYIAYNIGSSLNFKPY", "length": 327, "reference_go_mf": ["GO:0003886"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_ad65a2a9afbb74d766a8"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_294_1yq4_assembly1", "enzyme_name": "succinate dehydrogenase (ubiquinone)", "ec": ["1.3.5.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q9YHT1", "alignment_score": 1219.0, "observed_coverage": 1.0, "aligned_identity": 0.995114006514658, "canonical_span": [51, 665], "sequence": "MAAVVAASRSLAKCWLRPAVRAWPAACQTHARNFHFTVDGKKNASTKVSDSISTQYPVVDHEFDAVVVGAGGAGLRAAFGLSEAGFNTACVTKLFPTRSHTVAAQGGINAALGNMEDDNWRWHFYDTVKGSDWLGDQDAIHYMTEQAPAAVIELENYGMPFSRTEEGKIYQRAFGGQSLQFGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMENGECRGVIALCIEDGTIHRFRAKNTVIATGGYGRTYFSCTSAHTSTGDGTAMVTRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRSMTIEIREGRGCGPEKDHVYLQLHHLPPQQLATRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKGQVITHVNGEDKVVPGLYACGEAASASVHGANRLGANSLLDLVVFGRACALTIAETCKPGEPVPSIKPNAGEESVANLDKLRFADGTIRTSEARLNMQKTMQSHAAVFRTGSILQEGCEKLSQIYCDLAHLKTFDRGIVWNTDLVETLELQNLMLCALQTIYGAEARKESRGAHAREDYKFRIDDFDYSKPLQGQQKRPFEEHWRKHTLSYVDVKSGKVTLKYRPVIDRTLNEEDCSSVPPAIRSY", "length": 665, "reference_go_mf": ["GO:0009055", "GO:0050660", "GO:0160308", "GO:0008177"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_afa1adc7303764ba2297"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_295_1adn_assembly1", "enzyme_name": "methylphosphotriester-DNA--protein-cysteine S-methyltransferase", "ec": ["2.1.1.-"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P06134", "alignment_score": 175.0, "observed_coverage": 1.0, "aligned_identity": 0.967391304347826, "canonical_span": [0, 92], "sequence": "MKKATCLTDDQRWQSVLARDPNADGEFVFAVRTTGIFCRPSCRARHALRENVSFYANASEALAAGFRPCKRCQPEKANAQQHRLDKITHACRLLEQETPVTLEALADQVAMSPFHLHRLFKATTGMTPKAWQQAWRARRLRESLAKGESVTTSILNAGFPDSSSYYRKADETLGMTAKQFRHGGENLAVRYALADCELGRCLVAESERGICAILLGDDDATLISELQQMFPAADNAPADLMFQQHVREVIASLNQRDTPLTLPLDIRGTAFQQQVWQALRTIPCGETVSYQQLANAIGKPKAVRAVASACAANKLAIIIPCHRVVRGDGTLSGYRWGVSRKAQLLRREAENEER", "length": 354, "reference_go_mf": ["GO:0003700", "GO:0003908", "GO:0043565", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_2a3bbef74a03cf5ea3a4"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_297_1s6l_assembly1", "enzyme_name": "alkylmercury lyase", "ec": ["4.99.1.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P77072", "alignment_score": 384.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [20, 212], "sequence": "MKLAPYILELLTSVNRTNGTADLLVPLLRELAKGRPVSRTTLAGILDWPAERVAAVLEQATSTEYDKDGNIIGYGLTLRETSYVFEIDDRRLYAWCALDTLIFPALIGRTARVSSHCAATGAPVSLTVSPSEIQAVEPAGMAVSLVLPQEAADVRQSFCCHVHFFASVPTAEDWASKHQGLEGLAIVSVHEAFGLGQEFNRHLLQTMSSRTP", "length": 212, "reference_go_mf": ["GO:0018836"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_bdc2a788c02b3489ff6f"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_298_2pan_assembly1", "enzyme_name": "tartronate-semialdehyde synthase", "ec": ["4.1.1.47"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0AEP7", "alignment_score": 1010.0, "observed_coverage": 0.9912280701754386, "aligned_identity": 1.0, "canonical_span": [4, 589], "sequence": "MAKMRAVDAAMYVLEKEGITTAFGVPGAAINPFYSAMRKHGGIRHILARHVEGASHMAEGYTRATAGNIGVCLGTSGPAGTDMITALYSASADSIPILCITGQAPRARLHKEDFQAVDIEAIAKPVSKMAVTVREAALVPRVLQQAFHLMRSGRPGPVLVDLPFDVQVAEIEFDPDMYEPLPVYKPAASRMQIEKAVEMLIQAERPVIVAGGGVINADAAALLQQFAELTSVPVIPTLMGWGCIPDDHELMAGMVGLQTAHRYGNATLLASDMVFGIGNRFANRHTGSVEKYTEGRKIVHIDIEPTQIGRVLCPDLGIVSDAKAALTLLVEVAQEMQKAGRLPCRKEWVADCQQRKRTLLRKTHFDNVPVKPQRVYEEMNKAFGRDVCYVTTIGLSQIAAAQMLHVFKDRHWINCGQAGPLGWTIPAALGVCAADPKRNVVAISGDFDFQFLIEELAVGAQFNIPYIHVLVNNAYLGLIRQSQRAFDMDYCVQLAFENINSSEVNGYGVDHVKVAEGLGCKAIRVFKPEDIAPAFEQAKALMAQYRVPVVVEVILERVTNISMGSELDNVMEFEDIADNAADAPTETCFMHYE", "length": 593, "reference_go_mf": ["GO:0071949", "GO:0050660", "GO:0042802", "GO:0000287", "GO:0009028", "GO:0030976"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_2b98d30c13123e88ae01"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P0AEP7", "alignment_score": 1010.0, "observed_coverage": 0.9912280701754386, "aligned_identity": 1.0, "canonical_span": [4, 589], "sequence": "MAKMRAVDAAMYVLEKEGITTAFGVPGAAINPFYSAMRKHGGIRHILARHVEGASHMAEGYTRATAGNIGVCLGTSGPAGTDMITALYSASADSIPILCITGQAPRARLHKEDFQAVDIEAIAKPVSKMAVTVREAALVPRVLQQAFHLMRSGRPGPVLVDLPFDVQVAEIEFDPDMYEPLPVYKPAASRMQIEKAVEMLIQAERPVIVAGGGVINADAAALLQQFAELTSVPVIPTLMGWGCIPDDHELMAGMVGLQTAHRYGNATLLASDMVFGIGNRFANRHTGSVEKYTEGRKIVHIDIEPTQIGRVLCPDLGIVSDAKAALTLLVEVAQEMQKAGRLPCRKEWVADCQQRKRTLLRKTHFDNVPVKPQRVYEEMNKAFGRDVCYVTTIGLSQIAAAQMLHVFKDRHWINCGQAGPLGWTIPAALGVCAADPKRNVVAISGDFDFQFLIEELAVGAQFNIPYIHVLVNNAYLGLIRQSQRAFDMDYCVQLAFENINSSEVNGYGVDHVKVAEGLGCKAIRVFKPEDIAPAFEQAKALMAQYRVPVVVEVILERVTNISMGSELDNVMEFEDIADNAADAPTETCFMHYE", "length": 593, "reference_go_mf": ["GO:0071949", "GO:0050660", "GO:0042802", "GO:0000287", "GO:0009028", "GO:0030976"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_2b98d30c13123e88ae01"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_299_1b6t_assembly1", "enzyme_name": "pantetheine-phosphate adenylyltransferase", "ec": ["2.7.7.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0A6I6", "alignment_score": 314.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [2, 159], "sequence": "MQKRAIYPGTFDPITNGHIDIVTRATQMFDHVILAIAASPSKKPMFTLEERVALAQQATAHLGNVEVVGFSDLMANFARNQHATVLIRGLRAVADFEYEMQLAHMNRHLMPELESVFLMPSKEWSFISSSLVKEVARHQGDVTHFLPENVHQALMAKLA", "length": 159, "reference_go_mf": ["GO:0042802", "GO:0004595"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_e55f572ff53648b638f0"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_29_1djo_assembly1", "enzyme_name": "glutamin-(asparagin-)ase", "ec": ["3.5.1.38"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P10182", "alignment_score": 624.0, "observed_coverage": 1.0, "aligned_identity": 0.9636363636363636, "canonical_span": [7, 337], "sequence": "KEVENQQKLANVVILATGGTIAGAGASAANSATYQAAKVGVDKLIAGVPELADLANVRGEQVMQIASESITNDDLLKLGKRVAELADSNDVDGIVITHGTDTLEETAYFLDLTLNTDKPIVVVGSMRPGTAMSADGMLNLYNAVAVASNKDSRGKGVLVTMNDEIQSGRDVSKSINIKTEAFKSAWGPLGMVVEGKSYWFRLPAKRHTVNSEFDIKQISSLPQVDIAYSYGNVTDTAYKALAQNGAKALIHAGTGNGSVSSRLTPALQTLRKTGTQIIRSSHVNQGGFVLRNAEQPDDKNDWVVAHDLNPEKARILVELAMVKTQDSKELQRIFWEY", "length": 337, "reference_go_mf": ["GO:0004067", "GO:0050417", "GO:0004359"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_e30b11d649c07b1ae172"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P10182", "alignment_score": 624.0, "observed_coverage": 1.0, "aligned_identity": 0.9636363636363636, "canonical_span": [7, 337], "sequence": "KEVENQQKLANVVILATGGTIAGAGASAANSATYQAAKVGVDKLIAGVPELADLANVRGEQVMQIASESITNDDLLKLGKRVAELADSNDVDGIVITHGTDTLEETAYFLDLTLNTDKPIVVVGSMRPGTAMSADGMLNLYNAVAVASNKDSRGKGVLVTMNDEIQSGRDVSKSINIKTEAFKSAWGPLGMVVEGKSYWFRLPAKRHTVNSEFDIKQISSLPQVDIAYSYGNVTDTAYKALAQNGAKALIHAGTGNGSVSSRLTPALQTLRKTGTQIIRSSHVNQGGFVLRNAEQPDDKNDWVVAHDLNPEKARILVELAMVKTQDSKELQRIFWEY", "length": 337, "reference_go_mf": ["GO:0004067", "GO:0050417", "GO:0004359"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_e30b11d649c07b1ae172"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_2_1btl_assembly1", "enzyme_name": "beta-lactamase (Class A)", "ec": ["3.5.2.6"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P62593", "alignment_score": 520.0, "observed_coverage": 1.0, "aligned_identity": 0.9923954372623575, "canonical_span": [23, 286], "sequence": "MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW", "length": 286, "reference_go_mf": ["GO:0008800"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_c9c4ef97b0e66cb20b51"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_300_2pz0_assembly1", "enzyme_name": "glycerophosphodiester phosphodiesterase", "ec": ["3.1.4.46"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q8RB32", "alignment_score": 478.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 240], "sequence": "MKTLVIAHRGDSKNVPENTIAAFKRAMELGADGIELDVQLTKDGHLVVIHDETVDRTTNGEGFVKDFTLEEIKKLDAGIKFGEKFAGERIPTLYEVFELIGDKDFLVNIEIKSGIVLYPGIEEKLIKAIKEYNFEERVIISSFNHYSLRDVKKMAPHLKIGLLYQCGLVEPWHMALRMEAYSLHPFYFNIIPELVEGCKKNGVKLFPWTVDRKEDMERMIKAGVDGIITDDPETLINLVRKGG", "length": 243, "reference_go_mf": ["GO:0047389", "GO:0008889"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_86b2be9b14ad4c2dfe80"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_302_1ct9_assembly1", "enzyme_name": "asparagine synthase (glutamine-hydrolysing)", "ec": ["6.3.5.4"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P22106", "alignment_score": 971.5, "observed_coverage": 0.9979879275653923, "aligned_identity": 1.0, "canonical_span": [2, 517], "sequence": "MCSIFGVFDIKTDAVELRKKALELSRLMRHRGPDWSGIYASDNAILAHERLSIVDVNAGAQPLYNQQKTHVLAVNGEIYNHQALRAEYGDRYQFQTGSDCEVILALYQEKGPEFLDDLQGMFAFALYDSEKDAYLIGRDHLGIIPLYMGYDEHGQLYVASEMKALVPVCRTIKEFPAGSYLWSQDGEIRSYYHRDWFDYDAVKDNVTDKNELRQALEDSVKSHLMSDVPYGVLLSGGLDSSIISAITKKYAARRVEDQERSEAWWPQLHSFAVGLPGSPDLKAAQEVANHLGTVHHEIHFTVQEGLDAIRDVIYHIETYDVTTIRASTPMYLMSRKIKAMGIKMVLSGEGSDEVFGGYLYFHKAPNAKELHEETVRKLLALHMYDCARANKAMSAWGVEARVPFLDKKFLDVAMRINPQDKMCGNGKMEKHILRECFEAYLPASVAWRQKEQFSDGVGYSWIDTLKEVAAQQVSDQQLETARFRFPYNTPTSKEAYLYREIFEELFPLPSAAECVPGGPSVACSSAKAIEWDEAFKKMDDPSGRAVGVHQSAYK", "length": 554, "reference_go_mf": ["GO:0016597", "GO:0004066", "GO:0004071", "GO:0005524", "GO:0042802", "GO:0042803"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_77f4fc4aeece19ac5457"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_303_1mb9_assembly1", "enzyme_name": "(carboxyethyl)arginine beta-lactam-synthase", "ec": ["6.3.3.4"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0DJQ7", "alignment_score": 944.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [3, 507], "sequence": "MGAPVLPAAFGFLASARTGGGRAPGPVFATRGSHTDIDTPQGERSLAATLVHAPSVAPDRAVARSLTGAPTTAVLAGEIYNRDELLSVLPAGPAPEGDAELVLRLLERYDLHAFRLVNGRFATVVRTGDRVLLATDHAGSVPLYTCVAPGEVRASTEAKALAAHRDPKGFPLADARRVAGLTGVYQVPAGAVMDIDLGSGTAVTHRTWTPGLSRRILPEGEAVAAVRAALEKAVAQRVTPGDTPLVVLSGGIDSSGVAACAHRAAGELDTVSMGTDTSNEFREARAVVDHLRTRHREITIPTTELLAQLPYAVWASESVDPDIIEYLLPLTALYRALDGPERRILTGYGADIPLGGMHREDRLPALDTVLAHDMATFDGLNEMSPVLSTLAGHWTTHPYWDREVLDLLVSLEAGLKRRHGRDKWVLRAAMADALPAETVNRPKLGVHEGSGTTSSFSRLLLDHGVAEDRVHEAKRQVVRELFDLTVGGGRHPSEVDTDDVVRSVADRTARGAA", "length": 513, "reference_go_mf": ["GO:0034027", "GO:0004066"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_cd8a1c1f78eb1327d7fa"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_304_1ea0_assembly1", "enzyme_name": "glutamate synthase (NADPH)", "ec": ["1.4.1.13"], "controls": [{"chain": "A", "status": "reference_overlength", "selected": {"accession": "Q05755", "alignment_score": 2877.5, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [36, 1508], "sequence": "MTTELNQGEQFVADFRANAAALTTANAYNPEDEHDACGVGFIAAIDGKPRRSVVEKGIEALKAVWHRGAVDADGKTGDGAGIHVAVPQKFFKDHVKVIGHRAPDNKLAVGQVFLPRISLDAQEACRCIVETEILAFGYYIYGWRQVPINVDIIGEKANATRPEIEQIIVGNNKGVSDEQFELDLYIIRRRIEKAVKGEQINDFYICSLSARSIIYKGMFLAEQLTTFYPDLLDERFESDFAIYHQRYSTNTFPTWPLAQPFRMLAHNGEINTVKGNVNWMKAHETRMEHPAFGTHMQDLKPVIGVGLSDSGSLDTVFEVMVRAGRTAPMVKMMLVPQALTSSQTTPDNHKALIQYCNSVMEPWDGPAALAMTDGRWVVGGMDRNGLRPMRYTITTDGLIIGGSETGMVKIDETQVIEKGRLGPGEMIAVDLQSGKLYRDRELKDHLATLKPWDKWVQNTTHLDELVKTASLKGEPSDMDKAELRRRQQAFGLTMEDMELILHPMVEDGKEAIGSMGDDSPIAVLSDKYRGLHHFFRQNFSQVTNPPIDSLRERRVMSLKTRLGNLGNILDEDETQTRLLQLESPVLTTAEFRAMRDYMGDTAAEIDATFPVDGGPEALRDALRRIRQETEDAVRGGATHVILTDEAMGPARAAIPAILATGAVHTHLIRSNLRTFTSLNVRTAEGLDTHYFAVLIGVGATTVNAYLAQEAIAERHRRGLFGSMPLEKGMANYKKAIDDGLLKIMSKMGISVISSYRGGGNFEAIGLSRALVAEHFPAMVSRISGIGLNGIQKKVLEQHATAYNEEVVALPVGGFYRFRKSGDRHGWEGGVIHTLQQAVTNDSYTTFKKYSEQVNKRPPMQLRDLLELRSTKAPVPVDEVESITAIRKRFITPGMSMGALSPEAHGTLNVAMNRIGAKSDSGEGGEDPARFRPDKNGDNWNSAIKQVASGRFGVTAEYLNQCRELEIKVAQGAKPGEGGQLPGFKVTEMIARLRHSTPGVMLISPPPHHDIYSIEDLAQLIYDLKQINPDAKVTVKLVSRSGIGTIAAGVAKANADIILISGNSGGTGASPQTSIKFAGLPWEMGLSEVHQVLTLNRLRHRVRLRTDGGLKTGRDIVIAAMLGAEEFGIGTASLIAMGCIMVRQCHSNTCPVGVCVQDDKLRQKFVGTPEKVVNLFTFLAEEVREILAGLGFRSLNEVIGRTDLLHQVSRGAEHLDDLDLNPRLAQVDPGENARYCTLQGRNEVPDTLDARIVADARPLFEEGEKMQLAYNARNTQRAIGTRLSSMVTRKFGMFGLQPGHITIRLRGTAGQSLGAFAVQGIKLEVMGDANDYVGKGLSGGTIVVRPTTSSPLETNKNTIIGNTVLYGATAGKLFAAGQAGERFAVRNSGATVVVEGCGSNGCEYMTGGTAVILGRVGDNFAAGMTGGMAYVYDLDDSLPLYINDESVIFQRIEVGHYESQLKHLIEEHVTETQSRFAAEILNDWAREVTKFWQVVPKEMLNRLEVPVHLPKAISAE", "length": 1515, "reference_go_mf": ["GO:0004355"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_305_1et0_assembly1", "enzyme_name": "aminodeoxychorismate lyase (class IV)", "ec": ["4.1.3.38"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P28305", "alignment_score": 496.5, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 266], "sequence": "MFLINGHKQESLAVSDRATQFGDGCFTTARVIDGKVSLLSAHIQRLQDACQRLMISCDFWPQLEQEMKTLAAEQQNGVLKVVISRGSGGRGYSTLNSGPATRILSVTAYPAHYDRLRNEGITLALSPVRLGRNPHLAGIKHLNRLEQVLIRSHLEQTNADEALVLDSEGWVTECCAANLFWRKGNVVYTPRLDQAGVNGIMRQFCIRLLAQSSYQLVEVQASLEESLQADEMVICNALMPVMPVCACGDVSFSSATLYEYLAPLCERPN", "length": 269, "reference_go_mf": ["GO:0008696", "GO:0030170"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_70f8ec00c033327b4c57"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_307_3cmm_assembly1", "enzyme_name": "E1 ubiquitin-activating enzyme", "ec": ["6.2.1.45"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P22515", "alignment_score": 1985.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [11, 1024], "sequence": "MSSNNSGLSAAGEIDESLYSRQLYVLGKEAMLKMQTSNVLILGLKGLGVEIAKNVVLAGVKSMTVFDPEPVQLADLSTQFFLTEKDIGQKRGDVTRAKLAELNAYVPVNVLDSLDDVTQLSQFQVVVATDTVSLEDKVKINEFCHSSGIRFISSETRGLFGNTFVDLGDEFTVLDPTGEEPRTGMVSDIEPDGTVTMLDDNRHGLEDGNFVRFSEVEGLDKLNDGTLFKVEVLGPFAFRIGSVKEYGEYKKGGIFTEVKVPRKISFKSLKQQLSNPEFVFSDFAKFDRAAQLHLGFQALHQFAVRHNGELPRTMNDEDANELIKLVTDLSVQQPEVLGEGVDVNEDLIKELSYQARGDIPGVVAFFGGLVAQEVLKACSGKFTPLKQFMYFDSLESLPDPKNFPRNEKTTQPVNSRYDNQIAVFGLDFQKKIANSKVFLVGSGAIGCEMLKNWALLGLGSGSDGYIVVTDNDSIEKSNLNRQFLFRPKDVGKNKSEVAAEAVCAMNPDLKGKINAKIDKVGPETEEIFNDSFWESLDFVTNALDNVDARTYVDRRCVFYRKPLLESGTLGTKGNTQVIIPRLTESYSSSRDPPEKSIPLCTLRSFPNKIDHTIAWAKSLFQGYFTDSAENVNMYLTQPNFVEQTLKQSGDVKGVLESISDSLSSKPHNFEDCIKWARLEFEKKFNHDIKQLLFNFPKDAKTSNGEPFWSGAKRAPTPLEFDIYNNDHFHFVVAGASLRAYNYGIKSDDSNSKPNVDEYKSVIDHMIIPEFTPNANLKIQVNDDDPDPNANAANGSDEIDQLVSSLPDPSTLAGFKLEPVDFEKDDDTNHHIEFITACSNCRAQNYFIETADRQKTKFIAGRIIPAIATTTSLVTGLVNLELYKLIDNKTDIEQYKNGFVNLALPFFGFSEPIASPKGEYNNKKYDKIWDRFDIKGDIKLSDLIEHFEKDEGLEITMLSYGVSLLYASFFPPKKLKERLNLPITQLVKLVTKKDIPAHVSTMILEICADDKEGEDVEVPFITIHL", "length": 1024, "reference_go_mf": ["GO:0004839"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_ca8af6f9cd05492fb385"}, "alternative_alignments": [{"accession": "P06104", "alignment_score": 9.0, "observed_coverage": 0.008991008991008992, "aligned_identity": 0.6666666666666666, "canonical_span": [163, 172], "length": 172, "reference_go_mf": ["GO:0070628", "GO:0061631", "GO:0004842"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_308_1xld_assembly1", "enzyme_name": "xylose isomerase (actinobacterial)", "ec": ["5.3.1.5"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P12070", "alignment_score": 786.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [2, 395], "sequence": "MSVQPTPADHFTFGLWTVGWTGADPFGVATRKNLDPVEAVHKLAELGAYGITFHDNDLIPFDATEAEREKILGDFNQALKDTGLKVPMVTTNLFSHPVFKDGGFTSNDRSIRRFALAKVLHNIDLAAEMGAETFVMWGGREGSEYDGSKDLAAALDRMREGVDTAAGYIKDKGYNLRIALEPKPNEPRGDIFLPTVGHGLAFIEQLEHGDIVGLNPETGHEQMAGLNFTHGIAQALWAEKLFHIDLNGQRGIKYDQDLVFGHGDLTSAFFTVDLLENGFPNGGPKYTGPRHFDYKPSRTDGYDGVWDSAKANMSMYLLLKERALAFRADPEVQEAMKTSGVFELGETTLNAGESAADLMNDSASFAGFDAEAAAERNFAFIRLNQLAIEHLLGSR", "length": 395, "reference_go_mf": ["GO:0000287", "GO:0009045"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_589a9f2595670b071207"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_309_1ile_assembly1", "enzyme_name": "isoleucine-tRNA ligase (type 2)", "ec": ["6.1.1.5"], "controls": [{"chain": "A", "status": "reference_overlength", "selected": {"accession": "P56690", "alignment_score": 1627.0, "observed_coverage": 1.0, "aligned_identity": 0.9939098660170523, "canonical_span": [0, 821], "sequence": "MFKEVGEPNFPKLEEEVLAFWKREKIFQKSVENRKGGPRYTVYEGPPTANGLPHVGHAQARSYKDLFPRYKTMRGYYAPRRAGWDTHGLPVELEVEKKLGLKSKREIEAYGIERFNQACRESVFTYEKEWEAFTERIAYWVDLENAYATLEPTYIESIWWSLKNLFDRGLLYRDHKVVPYCPRCGTPLSSHEVALGYKEIQDPSVYVRFPLKEPKKLGLEKASLLIWTTTPWTLPGNVAAAVHPEYTYAAFQVGDEALILEEGLGRKLLGEGTPVLKTFPGKALEGLPYTPPYPQALEKGYFVVLADYVSQEDGTGIVHQAPAFGAEDLETARVYGLPLLKTVDEEGKLLVEPFKGLYFREANRAILRDLRGRGLLFKEESYLHSYPHCWRCSTPLMYYATESWFIKNTLFKDELIRKNQEIHWVPPHIKEGRYGEWLKNLVDWALSRNRYWGTPLPIWVCQACGKEEAIGSFQELKARATKPLPEPFDPHRPYVDQVELACACGGTMRRVPYVIDVWYDSGAMPFASLHYPFEHEEVFRESFPADFIAEGIDQTRGWFNSLHQLGVMLFGSIAFKNVICHGLILDEKGQKMSKSKGNVVDPWDIIREFGADALRWYIYVSAPPEADRRFGPNLVRETVRDYFLTLWNVYSFFVTYANLDRPDLKNPPPPEKRPEMDRWLLARMQDLIQRVTEALEAYDPTTSARALRDFVVEDLSQWYVRRNRRRFWKNEDALDREAAYATLYEALVLVATLAAPFTPFLAEVLWQNLVRSVRPEAKESVHLADWPEADPALADEALVAQMRAVLKVVDLARAARAKSGVKTRTPLPLLLVTAPTALEREGLKRFAHEIAEELNVKEVRVLEPGEEILSYRVLPNLKLLGRKYGKLVPKIREALQRERERAAALALKGEAIPLEVEGEALTLLPEEVLLEAEAPKGYQALEKDGYVAALKVEVTEALRMEGLARDLIRLLQQARKDMGLKVSDRIRVGYEAEGPYLEALKRHGPWIAEEVLATAFGEGLFGGFEARVEDEEGKAVFHLARAE", "length": 1043, "reference_go_mf": ["GO:0002161", "GO:0005524", "GO:0004822", "GO:0000049", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_30_2pfl_assembly1", "enzyme_name": "formate C-acetyltransferase", "ec": ["2.3.1.54"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P09373", "alignment_score": 1518.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 760], "sequence": "MSELNEKLATAWEGFTKGDWQNEVNVRDFIQKNYTPYEGDESFLAGATEATTTLWDKVMEGVKLENRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQTEAPLKRALIPFGGIKMIEGSCKAYNRELDPMIKKIFTEYRKTHNQGVFDVYTPDILRCRKSGVLTGLPDAYGRGRIIGDYRRVALYGIDYLMKDKLAQFTSLQADLENGVNLEQTIRLREEIAEQHRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVSIDTSSLQYENDDLMRPDFNNDDYAIACCVSPMIVGKQMQFFGARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACGIAGLSVAADSLSAIKYAKVKPIRDEDGLAIDFEIEGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQSM", "length": 760, "reference_go_mf": ["GO:0008861"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_93cd68b8a4b60a3dfd6e"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_310_1e4e_assembly1", "enzyme_name": "D-alanine-(R)-lactate ligase", "ec": ["6.1.2.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P25051", "alignment_score": 670.0, "observed_coverage": 1.0, "aligned_identity": 0.9882697947214076, "canonical_span": [1, 342], "sequence": "MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGITKSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKSGEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPVAATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCAVLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETAKKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELIDRLIVLALKG", "length": 343, "reference_go_mf": ["GO:0005524", "GO:0160220", "GO:0008716", "GO:0046872"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_61b422a6adb27516efa7"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_311_7enl_assembly1", "enzyme_name": "phosphopyruvate hydratase", "ec": ["4.2.1.11"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00924", "alignment_score": 866.0, "observed_coverage": 1.0, "aligned_identity": 0.9954128440366973, "canonical_span": [1, 437], "sequence": "MAVSKVYARSVYDSRGNPTVEVELTTEKGVFRSIVPSGASTGVHEALEMRDGDKSKWMGKGVLHAVKNVNDVIAPAFVKANIDVKDQKAVDDFLISLDGTANKSKLGANAILGVSLAASRAAAAEKNVPLYKHLADLSKSKTSPYVLPVPFLNVLNGGSHAGGALALQEFMIAPTGAKTFAEALRIGSEVYHNLKSLTKKRYGASAGNVGDEGGVAPNIQTAEEALDLIVDAIKAAGHDGKIKIGLDCASSEFFKDGKYDLDFKNPNSDKSKWLTGPQLADLYHSLMKRYPIVSIEDPFAEDDWEAWSHFFKTAGIQIVADDLTVTNPKRIATAIEKKAADALLLKVNQIGTLSESIKAAQDSFAAGWGVMVSHRSGETEDTFIADLVVGLRTGQIKTGAPARSERLAKLNQLLRIEEELGDNAVFAGENFHHGDKL", "length": 437, "reference_go_mf": ["GO:0000287", "GO:1904408", "GO:0004634"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_78e4db2834dfe93e67d6"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_312_1kq3_assembly1", "enzyme_name": "glycerol dehydrogenase", "ec": ["1.1.1.6"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q9WYQ4", "alignment_score": 726.0, "observed_coverage": 0.9972527472527473, "aligned_identity": 1.0, "canonical_span": [0, 363], "sequence": "MITTTIFPGRYVQGAGAINILEEELSRFGERAFVVIDDFVDKNVLGENFFSSFTKVRVNKQIFGGECSDEEIERLSGLVEEETDVVVGIGGGKTLDTAKAVAYKLKKPVVIVPTIASTDAPCSALSVIYTPNGEFKRYLFLPRNPDVVLVDTEIVAKAPARFLVAGMGDALATWFEAESCKQKYAPNMTGRLGSMTAYALARLCYETLLEYGVLAKRSVEEKSVTPALEKIVEANTLLSGLGFESGGLAAAHAIHNGLTVLENTHKYLHGEKVAIGVLASLFLTDKPRKMIEEVYSFCEEVGLPTTLAEIGLDGVSDEDLMKVAEKACDKNETIHNEPQPVTSKDVFFALKAADRYGRMRKNLT", "length": 364, "reference_go_mf": ["GO:0008888", "GO:0046872"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_f40a78a4b78c4cb919c0"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_313_1diz_assembly1", "enzyme_name": "DNA-3-methyladenine glycosylase II", "ec": ["3.2.2.21"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P04395", "alignment_score": 564.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 282], "sequence": "MYTLNWQPPYDWSWMLGFLAARAVSSVETVADSYYARSLAVGEYRGVVTAIPDIARHTLHINLSAGLEPVAAECLAKMSRLFDLQCNPQIVNGALGRLGAARPGLRLPGCVDAFEQGVRAILGQLVSVAMAAKLTARVAQLYGERLDDFPEYICFPTPQRLAAADPQALKALGMPLKRAEALIHLANAALEGTLPMTIPGDVEQAMKTLQTFPGIGRWTANYFALRGWQAKDVFLPDDYLIKQRFPGMTPAQIRRYAERWKPWRSYALLHIWYTEGWQPDEA", "length": 282, "reference_go_mf": ["GO:0032131", "GO:0003905", "GO:0008725", "GO:0043916"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_1b2269e43a32d3849107"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_314_1qdl_assembly1", "enzyme_name": "anthranilate synthase", "ec": ["4.1.3.27"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q06128", "alignment_score": 819.0, "observed_coverage": 0.9975903614457832, "aligned_identity": 1.0, "canonical_span": [0, 421], "sequence": "MEVHPISEFASPFEVFKCIERDFKVAGLLESIGGPQYKARYSVIAWSTNGYLKIHDDPVNILNGYLKDLKLADIPGLFKGGMIGYISYDAVRFWEKIRDLKPAAEDWPYAEFFTPDNIIIYDHNEGKVYVNADLSSVGGCGDIGEFKVSFYDESLNKNSYERIVSESLEYIRSGYIFQVVLSRFYRYIFSGDPLRIYYNLRRINPSPYMFYLKFDEKYLIGSSPELLFRVQDNIVETYPIAGTRPRGADQEEDLKLELELMNSEKDKAEHLMLVDLARNDLGKVCVPGTVKVPELMYVEKYSHVQHIVSKVIGTLKKKYNALNVLSATFPAGTVSGAPKPMAMNIIETLEEYKRGPYAGAVGFISADGNAEFAIAIRTAFLNKELLRIHAGAGIVYDSNPESEYFETEHKLKALKTAIGVR", "length": 421, "reference_go_mf": ["GO:0004049"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_5519e97b729122292a61"}, "alternative_alignments": [{"accession": "Q06129", "alignment_score": 9.0, "observed_coverage": 0.014457831325301205, "aligned_identity": 0.8333333333333334, "canonical_span": [45, 51], "length": 195, "reference_go_mf": ["GO:0004049"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}, {"chain": "B", "status": "assigned", "selected": {"accession": "Q06129", "alignment_score": 387.0, "observed_coverage": 1.0, "aligned_identity": 0.9948717948717949, "canonical_span": [0, 195], "sequence": "MDLTLIIDNYDSFVYNIAQIVGELGSYPIVIRNDEISIKGIERIDPDRIIISPGPGTPEKREDIGVSLDVIKYLGKRTPILGVCLGHQAIGYAFGAKIRRARKVFHGKISNIILVNNSPLSLYYGIAKEFKATRYHSLVVDEVHRPLIVDAISAEDNEIMAIHHEEYPIYGVQFHPESVGTSLGYKILYNFLNRV", "length": 195, "reference_go_mf": ["GO:0004049"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_27c9f4052565f2393093"}, "alternative_alignments": [{"accession": "Q06128", "alignment_score": 8.0, "observed_coverage": 0.035897435897435895, "aligned_identity": 0.7142857142857143, "canonical_span": [235, 242], "length": 421, "reference_go_mf": ["GO:0004049"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_315_1ey3_assembly1", "enzyme_name": "enoyl-CoA hydratase", "ec": ["4.2.1.17"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P14604", "alignment_score": 516.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [32, 290], "sequence": "MAALRALLPRACNSLLSPVRCPEFRRFASGANFQYIITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKAFAAGADIKEMQNRTFQDCYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMCDIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFATDDRREGMSAFVEKRKANFKDH", "length": 290, "reference_go_mf": ["GO:0120092", "GO:0043956", "GO:0004165", "GO:0004300"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_ffe631178e89ddce0fca"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_316_1j21_assembly1", "enzyme_name": "argininosuccinate synthetase", "ec": ["6.3.4.5"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P59846", "alignment_score": 741.5, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 395], "sequence": "MKIVLAYSGGLDTSIILKWLKETYRAEVIAFTADIGQGEEVEEAREKALRTGASKAIALDLKEEFVRDFVFPMMRAGAVYEGYYLLGTSIARPLIAKHLVRIAEEEGAEAIAHGATGKGNDQVRFELTAYALKPDIKVIAPWREWSFQGRKEMIAYAEAHGIPVPVTQEKPYSMDANLLHISYEGGVLEDPWAEPPKGMFRMTQDPEEAPDAPEYVEVEFFEGDPVAVNGERLSPAALLQRLNEIGGRHGVGRVDIVENRFVGMKSRGVYETPGGTILYHARRAVESLTLDREVLHQRDMLSPKYAELVYYGFWYAPEREALQAYFDHVARSVTGVARLKLYKGNVYVVGRKAPKSLYRQDLVSFDEAGGYDQKDAEGFIKIQALRLRVRALVEREGHGA", "length": 400, "reference_go_mf": ["GO:0004055", "GO:0005524"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_3e6ecf884ac88d91fc0f"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_317_1uag_assembly1", "enzyme_name": "UDP-N-acetylmuramoyl-L-alanine---D-glutamate ligase", "ec": ["6.3.2.9"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P14900", "alignment_score": 832.5, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 438], "sequence": "MADYQGKNVVIIGLGLTGLSCVDFFLARGVTPRVMDTRMTPPGLDKLPEAVERHTGSLNDEWLMAADLIVASPGIALAHPSLSAAADAGIEIVGDIELFCREAQAPIVAITGSNGKSTVTTLVGEMAKAAGVNVGVGGNIGLPALMLLDDECELYVLELSSFQLETTSSLQAVAATILNVTEDHMDRYPFGLQQYRAAKLRIYENAKVCVVNADDALTMPIRGADERCVSFGVNMGDYHLNHQQGETWLRVKGEKVLNVKEMKLSGQHNYTNALAALALADAAGLPRASSLKALTTFTGLPHRFEVVLEHNGVRWINDSKATNVGSTEAALNGLHVDGTLHLLLGGDGKSADFSPLARYLNGDNVRLYCFGRDGAQLAALRPEVAEQTETMEQAMRLLAPRVQPGDMVLLSPACASLDQFKNFEQRGNEFARLAKELG", "length": 438, "reference_go_mf": ["GO:0005524", "GO:0042802", "GO:0008764"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_4de0dae21f8d20995048"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_319_1oya_assembly1", "enzyme_name": "NADPH dehydrogenase", "ec": ["1.6.99.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q02899", "alignment_score": 798.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 400], "sequence": "MSFVKDFKPQALGDTNLFKPIKIGNNELLHRAVIPPLTRMRALHPGNIPNRDWAVEYYTQRAQRPGTMIITEGAFISPQAGGYDNAPGVWSEEQMVEWTKIFNAIHEKKSFVWVQLWVLGWAAFPDNLARDGLRYDSASDNVFMDAEQEAKAKKANNPQHSLTKDEIKQYIKEYVQAAKNSIAAGADGVEIHSANGYLLNQFLDPHSNTRTDEYGGSIENRARFTLEVVDALVEAIGHEKVGLRLSPYGVFNSMSGGAETGIVAQYAYVAGELEKRAKAGKRLAFVHLVEPRVTNPFLTEGEGEYEGGSNDFVYSIWKGPVIRAGNFALHPEVVREEVKDKRTLIGYGRFFISNPDLVDRLEKGLPLNKYDRDTFYQMSAHGYIDYPTYEEALKLGWDKK", "length": 400, "reference_go_mf": ["GO:0010181", "GO:0003959"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_541bde7fb942c730a7a2"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_31_1lcb_assembly1", "enzyme_name": "thymidylate synthase", "ec": ["2.1.1.45"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00469", "alignment_score": 632.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 316], "sequence": "MLEQPYLDLAKKVLDEGHFKPDRTHTGTYSIFGHQMRFDLSKGFPLLTTKKVPFGLIKSELLWFLHGDTNIRFLLQHRNHIWDEWAFEKWVKSDEYHGPDMTDFGHRSQKDPEFAAVYHEEMAKFDDRVLHDDAFAAKYGDLGLVYGSQWRAWHTSKGDTIDQLGDVIEQIKTHPYSRRLIVSAWNPEDVPTMALPPCHTLYQFYVNDGKLSLQLYQRSADIFLGVPFNIASYALLTHLVAHECGLEVGEFIHTFGDAHLYVNHLDQIKEQLSRTPRPAPTLQLNPDKHDIFDFDMKDIKLLNYDPYPAIKAPVAV", "length": 316, "reference_go_mf": ["GO:0004799"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_8872a5ded9b1f61cb4b5"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_321_1yt3_assembly1", "enzyme_name": "ribonuclease D", "ec": ["3.1.13.5"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P09155", "alignment_score": 750.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 375], "sequence": "MNYQMITTDDALASLCEAVRAFPAIALDTEFVRTRTYYPQLGLIQLFDGEHLALIDPLGITDWSPLKAILRDPSITKFLHAGSEDLEVFLNVFGELPQPLIDTQILAAFCGRPMSWGFASMVEEYSGVTLDKSESRTDWLARPLTERQCEYAAADVWYLLPITAKLMVETEASGWLPAALDECRLMQMRRQEVVAPEDAWRDITNAWQLRTRQLACLQLLADWRLRKARERDLAVNFVVREEHLWSVARYMPGSLGELDSLGLSGSEIRFHGKTLLALVEKAQTLPEDALPQPMLNLMDMPGYRKAFKAIKSLITDVSETHKISAELLASRRQINQLLNWHWKLKPQNNLPELISGWRGELMAEALHNLLQEYPQ", "length": 375, "reference_go_mf": ["GO:0000175", "GO:0003676", "GO:0000166", "GO:0033890"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_c3c00ba9a9169593e38f"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_322_1gog_assembly1", "enzyme_name": "galactose oxidiase", "ec": ["1.1.3.9"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0CS93", "alignment_score": 1278.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [41, 680], "sequence": "MKHLLTLALCFSSINAVAVTVPHKAVGTGIPEGSLQFLSLRASAPIGSAISRNNWAVTCDSAQSGNECNKAIDGNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSMLPRQDGNQNGWIGRHEVYLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAITEANGQPWTSIAEINVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAFGGSPGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGNDAKKTSLYDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSWSGGVFEKNGEVYSPSSKTWTSLPNAKVNPMLTADKQGLYRSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGSGDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYQDSDATTNAHIITLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFTPEIYVPEQDTFYKQNPNSIVRVYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQIFTPNYLYNSNGNLATRPKITRTSTQSVKVGGRITISTDSSISKASLIRYGTATHTVNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRVTQ", "length": 680, "reference_go_mf": ["GO:0045480"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_a984608dd5ae7b9d83bf"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_323_2akj_assembly1", "enzyme_name": "nitrate reductase", "ec": ["1.7.7.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P05314", "alignment_score": 1070.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [53, 588], "sequence": "MASLPVNKIIPSSTTLLSSSNNNRRRNNSSIRCQKAVSPAAETAAVSPSVDAARLEPRVEERDGFWVLKEEFRSGINPAEKVKIEKDPMKLFIEDGISDLATLSMEEVDKSKHNKDDIDVRLKWLGLFHRRKHHYGRFMMRLKLPNGVTTSEQTRYLASVIKKYGKDGCADVTTRQNWQIRGVVLPDVPEIIKGLESVGLTSLQSGMDNVRNPVGNPLAGIDPHEIVDTRPFTNLISQFVTANSRGNLSITNLPRKWNPCVIGSHDLYEHPHINDLAYMPATKNGKFGFNLLVGGFFSIKRCEEAIPLDAWVSAEDVVPVCKAMLEAFRDLGFRGNRQKCRMMWLIDELGMEAFRGEVEKRMPEQVLERASSEELVQKDWERREYLGVHPQKQQGLSFVGLHIPVGRLQADEMEELARIADVYGSGELRLTVEQNIIIPNVENSKIDSLLNEPLLKERYSPEPPILMKGLVACTGSQFCGQAIIETKARALKVTEEVQRLVSVTRPVRMHWTGCPNSCGQVQVADIGFMGCMTRDENGKPCEGADVFVGGRIGSDSHLGDIYKKAVPCKDLVPVVAEILINQFGAVPREREEAE", "length": 594, "reference_go_mf": ["GO:0048307", "GO:0020037", "GO:0051536", "GO:0016491"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_b34bdbf47e095fec727a"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_324_1tph_assembly1", "enzyme_name": "triosephosphate isomerase", "ec": ["5.3.1.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00940", "alignment_score": 487.0, "observed_coverage": 1.0, "aligned_identity": 0.9959183673469387, "canonical_span": [3, 248], "sequence": "MAPRKFFVGGNWKMNGDKKSLGELIHTLNGAKLSADTEVVCGAPSIYLDFARQKLDAKIGVAAQNCYKVPKGAFTGEISPAMIKDIGAAWVILGHSERRHVFGESDELIGQKVAHALAEGLGVIACIGEKLDEREAGITEKVVFEQTKAIADNVKDWSKVVLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKSHVSDAVAQSTRIIYGGSVTGGNCKELASQHDVDGFLVGGASLKPEFVDIINAKH", "length": 248, "reference_go_mf": ["GO:0008929", "GO:0042803", "GO:0004807", "GO:0031625"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_411fc82e88b66531c4e8"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_325_2eua_assembly1", "enzyme_name": "isochorismate synthase (menaquinone-specific)", "ec": ["5.4.4.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P38051", "alignment_score": 856.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 429], "sequence": "MQSLTTALENLLRHLSQEIPATPGIRVIDIPFPLKDAFDALSWLASQQTYPQFYWQQRNGDEEAVVLGAITRFTSLDQAQRFLRQHPEHADLRIWGLNAFDPSQGNLLLPRLEWRRCGGKATLRLTLFSESSLQHDAIQAKEFIATLVSIKPLPGLHLTTTREQHWPDKTGWTQLIELATKTIAEGELDKVVLARATDLHFASPVNAAAMMAASRRLNLNCYHFYMAFDGENAFLGSSPERLWRRRDKALRTEALAGTVANNPDDKQAQQLGEWLMADDKNQRENMLVVEDICQRLQADTQTLDVLPPQVLRLRKVQHLRRCIWTSLNKADDVICLHQLQPTAAVAGLPRDLARQFIARHEPFTREWYAGSAGYLSLQQSEFCVSLRSAKISGNVVRLYAGAGIVRGSDPEQEWQEIDNKAAGLRTLLQME", "length": 431, "reference_go_mf": ["GO:0008909", "GO:0000287"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_ba280341a1dda960e97f"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_326_1pkn_assembly1", "enzyme_name": "pyruvate kinase", "ec": ["2.7.1.40"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P11974", "alignment_score": 1002.0, "observed_coverage": 1.0, "aligned_identity": 0.9883268482490273, "canonical_span": [12, 531], "sequence": "MSKSHSEAGSAFIQTQQLHAAMADTFLEHMCRLDIDSAPITARNTGIICTIGPASRSVETLKEMIKSGMNVARMNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVDVGSKVYVDDGLISLQVKQKGPDFLVTEVENGGFLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKAADVHEVRKILGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMIIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAMFHRKLFEELARSSSHSTDLMEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIAVTRNHQTARQAHLYRGIFPVVCKDPVQEAWAEDVDLRVNLAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP", "length": 531, "reference_go_mf": ["GO:0000287", "GO:0003729", "GO:0004715", "GO:0030955", "GO:0004674", "GO:0004713", "GO:0004743"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_00b88962474070965b1c"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_329_2ixj_assembly1", "enzyme_name": "dTDP-6-deoxy-D-xylo-4-hexulose 3,5 epimerase", "ec": ["5.1.3.13"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q9HU21", "alignment_score": 362.0, "observed_coverage": 0.9836956521739131, "aligned_identity": 1.0, "canonical_span": [0, 181], "sequence": "MKATRLAIPDVILFEPRVFGDDRGFFFESYNQRAFEEACGHPVSFVQDNHSRSARGVLRGLHYQIRQAQGKLVRATLGEVFDVAVDLRRGSPTFGQWVGERLSAENKRQMWIPAGFAHGFVVLSEYAEFLYKTTDFWAPEHERCIVWNDPELKIDWPLQDAPLLSEKDRQGKAFADADCFP", "length": 181, "reference_go_mf": ["GO:0008830"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_d860167c9b59a8bf38f7"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_32_1qin_assembly1", "enzyme_name": "lactoylglutathione lyase", "ec": ["4.4.1.5"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q04760", "alignment_score": 352.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [8, 184], "sequence": "MAEPQPPSGGLTDEAALSCCSDADPSTKDFLLQQTMLRVKDPKKSLDFYTRVLGMTLIQKCDFPIMKFSLYFLAYEDKNDIPKEKDEKIAWALSRKATLELTHNWGTEDDETQSYHNGNSDPRGFGHIGIAVPDVYSACKRFEELGVKFVKKPDDGKMKGLAFIQDPDGYWIEILNPNKMATLM", "length": 184, "reference_go_mf": ["GO:0004462", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_6dc93a921544fdbf2e39"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "Q04760", "alignment_score": 352.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [8, 184], "sequence": "MAEPQPPSGGLTDEAALSCCSDADPSTKDFLLQQTMLRVKDPKKSLDFYTRVLGMTLIQKCDFPIMKFSLYFLAYEDKNDIPKEKDEKIAWALSRKATLELTHNWGTEDDETQSYHNGNSDPRGFGHIGIAVPDVYSACKRFEELGVKFVKKPDDGKMKGLAFIQDPDGYWIEILNPNKMATLM", "length": 184, "reference_go_mf": ["GO:0004462", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_6dc93a921544fdbf2e39"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_330_2zr8_assembly1", "enzyme_name": "serine racemase", "ec": ["5.1.1.18"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "O59791", "alignment_score": 638.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [4, 323], "sequence": "MSDNLVLPTYDDVASASERIKKFANKTPVLTSSTVNKEFVAEVFFKCENFQKMGAFKFRGALNALSQLNEAQRKAGVLTFSSGNHAQAIALSAKILGIPAKIIMPLDAPEAKVAATKGYGGQVIMYDRYKDDREKMAKEISEREGLTIIPPYDHPHVLAGQGTAAKELFEEVGPLDALFVCLGGGGLLSGSALAARHFAPNCEVYGVEPEAGNDGQQSFRKGSIVHIDTPKTIADGAQTQHLGNYTFSIIKEKVDDILTVSDEELIDCLKFYAARMKIVVEPTGCLSFAAARAMKEKLKNKRIGIIISGGNVDIERYAHFLSQ", "length": 323, "reference_go_mf": ["GO:0005524", "GO:0008721", "GO:0003941", "GO:0000287", "GO:0042803", "GO:0030170", "GO:0030378"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_cb404f718b8dc5730788"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_331_1rm0_assembly1", "enzyme_name": "inositol-3-phosphate synthase", "ec": ["5.5.1.4"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P11986", "alignment_score": 1050.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [8, 533], "sequence": "MTEDNIAPITSVKVVTDKCTYKDNELLTKYSYENAVVTKTASGRFDVTPTVQDYVFKLDLKKPEKLGIMLIGLGGNNGSTLVASVLANKHNVEFQTKEGVKQPNYFGSMTQCSTLKLGIDAEGNDVYAPFNSLLPMVSPNDFVVSGWDINNADLYEAMQRSQVLEYDLQQRLKAKMSLVKPLPSIYYPDFIAANQDERANNCINLDEKGNVTTRGKWTHLQRIRRDIQNFKEENALDKVIVLWTANTERYVEVSPGVNDTMENLLQSIKNDHEEIAPSTIFAAASILEGVPYINGSPQNTFVPGLVQLAEHEGTFIAGDDLKSGQTKLKSVLAQFLVDAGIKPVSIASYNHLGNNDGYNLSAPKQFRSKEISKSSVIDDIIASNDILYNDKLGKKVDHCIVIKYMKPVGDSKVAMDEYYSELMLGGHNRISIHNVCEDSLLATPLIIDLLVMTEFCTRVSYKKVDPVKEDAGKFENFYPVLTFLSYWLKAPLTRPGFHPVNGLNKQRTALENFLRLLIGLPSQNELRFEERLL", "length": 533, "reference_go_mf": ["GO:0004512"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_a071b07219003887ece1"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_332_1uam_assembly1", "enzyme_name": "tRNA-(m1-G37)-methyl transferase", "ec": ["2.1.1.228"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P43912", "alignment_score": 481.5, "observed_coverage": 0.976, "aligned_identity": 1.0, "canonical_span": [0, 246], "sequence": "MWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVLGKQASAEEDSFADGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEHNS", "length": 246, "reference_go_mf": ["GO:0052906"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_d1eaf6dc845f5e54955c"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P43912", "alignment_score": 481.5, "observed_coverage": 0.976, "aligned_identity": 1.0, "canonical_span": [0, 246], "sequence": "MWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVLGKQASAEEDSFADGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEHNS", "length": 246, "reference_go_mf": ["GO:0052906"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_d1eaf6dc845f5e54955c"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_333_2o1x_assembly1", "enzyme_name": "1-deoxy-D-xylulose 5-phosphate synthase", "ec": ["2.2.1.7"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q9RUB5", "alignment_score": 1125.0, "observed_coverage": 1.0, "aligned_identity": 0.9982698961937716, "canonical_span": [4, 627], "sequence": "MNELPGTSDTPLLDQIHGPKDLKRLSREQLPALTEELRGEIVRVCSRGGLHLASSLGAVDIITALHYVLDSPRDRILFDVGHQAYAHKILTGRRDQMADIKKEGGISGFTKVSESEHDAITVGHASTSLANALGMALARDAQGKDFHVAAVIGDGSLTGGMALAALNTIGDMGRKMLIVLNDNEMSISENVGAMNKFMRGLQVQKWFQEGEGAGKKAVEAVSKPLADFMSRAKNSTRHFFDPASVNPFAAMGVRYVGPVDGHNVQELVWLLERLVDLDGPTILHIVTTKGKGLSYAEADPIYWHGPAKFDPATGEYVPSSAYSWSAAFGEAVTEWAKTDPRTFVVTPAMREGSGLVEFSRVHPHRYLDVGIAEEVAVTTAAGMALQGMRPVVAIYSTFLQRAYDQVLHDVAIEHLNVTFCIDRAGIVGADGATHNGVFDLSFLRSIPGVRIGLPKDAAELRGMLKYAQTHDGPFAIRYPRGNTAQVPAGTWPDLKWGEWERLKGGDDVVILAGGKALDYALKAAEDLPGVGVVNARFVKPLDEEMLREVGGRARALITVEDNTVVGGFGGAVLEALNSMNLHPTVRVLGIPDEFQEHATAESVHARAGIDAPAIRTVLAELGVDVPIEV", "length": 629, "reference_go_mf": ["GO:0008661", "GO:0000287", "GO:0030976"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_6a1c7eefe6967fc0409a"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_334_1bwz_assembly1", "enzyme_name": "diaminopimelate epimerase", "ec": ["5.1.1.7"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P44859", "alignment_score": 545.0, "observed_coverage": 1.0, "aligned_identity": 0.9963503649635036, "canonical_span": [0, 274], "sequence": "MQFSKMHGLGNDFVVVDGVTQNVFFTPETIRRLANRHCGIGFDQLLIVEAPYDPELDFHYRIFNADGSEVSQCGNGARCFARFVTLKGLTNKKDISVSTQKGNMVLTVKDDNQIRVNMGEPIWEPAKIPFTANKFEKNYILRTDIQTVLCGAVSMGNPHCVVQVDDIQTANVEQLGPLLESHERFPERVNAGFMQIINKEHIKLRVYERGAGETQACGSGACAAVAVGIMQGLLNNNVQVDLPGGSLMIEWNGVGHPLYMTGEATHIYDGFITL", "length": 274, "reference_go_mf": ["GO:0008837"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_aa5f7c14804803146b63"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_335_1jfl_assembly1", "enzyme_name": "aspartate racemase (CC-type)", "ec": ["5.1.1.13"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "O58403", "alignment_score": 456.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 228], "sequence": "MKTIGILGGMGPLATAELFRRIVIKTPAKRDQEHPKVIIFNNPQIPDRTAYILGKGEDPRPQLIWTAKRLEECGADFIIMPCNTAHAFVEDIRKAIKIPIISMIEETAKKVKELGFKKAGLLATTGTIVSGVYEKEFSKYGVEIMTPTEDEQKDVMRGIYEGVKAGNLKLGRELLLKTAKILEERGAECIIAGCTEVSVVLKQDDLKVPLIDPMDVIAEVAVKVALEK", "length": 228, "reference_go_mf": ["GO:0047689"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_9c41bdc1aa3ca4c84356"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_336_2hdh_assembly1", "enzyme_name": "L-3-hydroxyacyl-CoA dehydrogenase", "ec": ["1.1.1.35"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q16836", "alignment_score": 517.0, "observed_coverage": 0.993006993006993, "aligned_identity": 0.9894366197183099, "canonical_span": [23, 314], "sequence": "MAFVTRQFMRSVSSSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSKALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDASKEDIDTAMKLGAGYPMGPFELLDYVGLDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYKYK", "length": 314, "reference_go_mf": ["GO:0003857", "GO:0042802", "GO:0016509", "GO:0070403"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_44422865b2b1a4d71288"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_337_1chd_assembly1", "enzyme_name": "protein-glutamate methylesterase (CheB)", "ec": ["3.1.1.61"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P04042", "alignment_score": 396.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [151, 349], "sequence": "MSKIRVLSVDDSALMRQIMTEIINSHSDMEMVATAPDPLVARDLIKKFNPDVLTLDVEMPRMDGLDFLEKLMRLRPMPVVMVSSLTGKGSEVTLRALELGAIDFVTKPQLGIREGMLAYSEMIAEKVRTAARARIAAHKPMAAPTTLKAGPLLSSEKLIAIGASTGGTEAIRHVLQPLPLSSPAVIITQHMPPGFTRSFAERLNKLCQISVKEAEDGERVLPGHAYIAPGDKHMELARSGANYQIKIHDGPPVNRHRPSVDVLFHSVAKHAGRNAVGVILTGMGNDGAAGMLAMYQAGAWTIAQNEASCVVFGMPREAINMGGVSEVVDLSQVSQQMLAKISAGQAIRI", "length": 349, "reference_go_mf": ["GO:0000156", "GO:0008984", "GO:0050568"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_9f496d8df53c5ce1cfab"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_338_2id0_assembly1", "enzyme_name": "RNAse II", "ec": ["3.1.13.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P30850", "alignment_score": 1152.5, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [4, 644], "sequence": "MFQDNPLLAQLKQQLHSQTPRAEGVVKATEKGFGFLEVDAQKSYFIPPPQMKKVMHGDRIIAVIHSEKERESAEPEELVEPFLTRFVGKVQGKNDRLAIVPDHPLLKDAIPCRAARGLNHEFKEGDWAVAEMRRHPLKGDRSFYAELTQYITFGDDHFVPWWVTLARHNLEKEAPDGVATEMLDEGLVREDLTALDFVTIDSASTEDMDDALFAKALPDDKLQLIVAIADPTAWIAEGSKLDKAAKIRAFTNYLPGFNIPMLPRELSDDLCSLRANEVRPVLACRMTLSADGTIEDNIEFFAATIESKAKLVYDQVSDWLENTGDWQPESEAIAEQVRLLAQICQRRGEWRHNHALVFKDRPDYRFILGEKGEVLDIVAEPRRIANRIVEEAMIAANICAARVLRDKLGFGIYNVHMGFDPANADALAALLKTHGLHVDAEEVLTLDGFCKLRRELDAQPTGFLDSRIRRFQSFAEISTEPGPHFGLGLEAYATWTSPIRKYGDMINHRLLKAVIKGETATRPQDEITVQMAERRRLNRMAERDVGDWLYARFLKDKAGTDTRFAAEIVDISRGGMRVRLVDNGAIAFIPAPFLHAVRDELVCSQENGTVQIKGETVYKVTDVIDVTIAEVRMETRSIIARPVA", "length": 644, "reference_go_mf": ["GO:0008408", "GO:0008859", "GO:0003723"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_ca05a9bb2cdf206b37e6"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_33_1jc5_assembly1", "enzyme_name": "methylmalonyl-CoA epimerase", "ec": ["5.1.99.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q8VQN0", "alignment_score": 290.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [2, 147], "sequence": "MSNEDLFICIDHVAYACPDADEASKYYQETFGWHELHREENPEQGVVEIMMAPAAKLTEHMTQVQVMAPLNDESTVAKWLAKHNGRAGLHHMAWRVDDIDAVSATLRERGVQLLYDEPKLGTGGNRINFMHPKSGKGVLIELTQYPKN", "length": 148, "reference_go_mf": ["GO:0004493"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_2632e49fcf281d6fbb09"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_341_1sg4_assembly1", "enzyme_name": "3,2-trans-enoyl-CoA isomerase (mitochondrial)", "ec": ["5.3.3.8"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P42126", "alignment_score": 498.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [43, 292], "sequence": "MALVASVRVPARVLLRAGARLPGAALGRTERAAGGGDGARRFGSQRVLVEPDAGAGVAVMKFKNPPVNSLSLEFLTELVISLEKLENDKSFRGVILTSDRPGVFSAGLDLTEMCGRSPAHYAGYWKAVQELWLRLYQSNLVLVSAINGACPAGGCLVALTCDYRILADNPRYCIGLNETQLGIIAPFWLKDTLENTIGHRAAERALQLGLLFPPAEALQVGIVDQVVPEEQVQSTALSAIAQWMAIPDHARQLTKAMMRKATASRLVTQRDADVQNFVSFISKDSIQKSLQMYLERLKEEKG", "length": 302, "reference_go_mf": ["GO:0004165", "GO:0016863"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_f408e1015839782de990"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_342_1dci_assembly1", "enzyme_name": "delta(3,5)-delta(2,4)-dienoyl-CoA isomerase", "ec": ["5.3.3.-"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q62651", "alignment_score": 548.0, "observed_coverage": 0.9963636363636363, "aligned_identity": 1.0, "canonical_span": [53, 327], "sequence": "MATAMTVSSKLLGLLMQQLRGTRQLYFNVSLRSLSSSAQEASKRIPEEVSDHNYESIQVTSAQKHVLHVQLNRPEKRNAMNRAFWRELVECFQKISKDSDCRAVVVSGAGKMFTSGIDLMDMASDILQPPGDDVARIAWYLRDLISRYQKTFTVIEKCPKPVIAAIHGGCIGGGVDLISACDIRYCTQDAFFQVKEVDVGLAADVGTLQRLPKVIGNRSLVNELTFTARKMMADEALDSGLVSRVFPDKDVMLNAAFALAADISSKSPVAVQGSKINLIYSRDHSVDESLDYMATWNMSMLQTQDIIKSVQAAMEKKDSKSITFSKL", "length": 327, "reference_go_mf": ["GO:0051750"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_575c1068237dddd93aaf"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_343_1hzd_assembly1", "enzyme_name": "methylglutaconyl-CoA hydratase", "ec": ["4.2.1.18"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q13825", "alignment_score": 532.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [73, 339], "sequence": "MAAAVAAAPGALGSLHAGGARLVAACSAWLCPGLRLPGSLAGRRAGPAIWAQGWVPAAGGPAPKRGYSSEMKTEDELRVRHLEEENRGIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKERAKMSSSEVGPFVSKIRAVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAKAVGLISHVLEQNQEGDAAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIPTKDRLEGLLAFKEKRPPRYKGE", "length": 339, "reference_go_mf": ["GO:0004300", "GO:0050011", "GO:0004490", "GO:0003730"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_872d8ac20547a23d9692"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_344_2gtr_assembly1", "enzyme_name": "histone acetyltransferase (crotonase type)", "ec": ["2.3.1.48"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q9Y232", "alignment_score": 516.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [339, 597], "sequence": "MTFQASHRSAWGKSRKKNWQYEGPTQKLFLKRNNVSAPDGPSDPSISVSSEQSGAQQPPALQVERIVDKRKNKKGKTEYLVRWKGYDSEDDTWEPEQHLVNCEEYIHDFNRRHTEKQKESTLTRTNRTSPNNARKQISRSTNSNFSKTSPKALVIGKDHESKNSQLFAASQKFRKNTAPSLSSRKNMDLAKSGIKILVPKSPVKSRTAVDGFQSESPEKLDPVEQGQEDTVAPEVAAEKPVGALLGPGAERARMGSRPRIHPLVPQVPGPVTAAMATGLAVNGKGTSPFMDALTANGTTNIQTSVTGVTASKRKFIDDRRDQPFDKRLRFSVRQTESAYRYRDIVVRKQDGFTHILLSTKSSENNSLNPEVMREVQSALSTAAADDSKLVLLSAVGSVFCCGLDFIYFIRRLTDDRKRESTKMAEAIRNFVNTFIQFKKPIIVAVNGPAIGLGASILPLCDVVWANEKAWFQTPYTTFGQSPDGCSTVMFPKIMGGASANEMLLSGRKLTAQEACGKGLVSQVFWPGTFTQEVMVRIKELASCNPVVLEESKALVRCNMKMELEQANERECEVLKKIWGSAQGMDSMLKYLQRKIDEF", "length": 598, "reference_go_mf": ["GO:0120092", "GO:0003682", "GO:0061628", "GO:0062072", "GO:0042802", "GO:0030674", "GO:0003714"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_c99a8829d634437fcf2b"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_345_3bpt_assembly1", "enzyme_name": "3-hydroxyisobutyryl-CoA hydrolase", "ec": ["3.1.2.4"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q6NVY1", "alignment_score": 627.0, "observed_coverage": 0.9801136363636364, "aligned_identity": 0.9971014492753624, "canonical_span": [31, 386], "sequence": "MGQREMWRLMSRFNAFKRTNTILHHLRMSKHTDAAEEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKIDRDKSFILEEHMDKINSCFSANTVEEIIENLQQDGSSFALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACMRGHDFHEGVRAVLIDKDQSPKWKPADLKEVTEEDLNNHFKSLGSSDLKF", "length": 386, "reference_go_mf": ["GO:0003860"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_c2dac3219cb824d9ae2d"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_348_2chr_assembly1", "enzyme_name": "chloromuconate cycloisomerase", "ec": ["5.5.1.7"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P05404", "alignment_score": 740.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 370], "sequence": "MKIDAIEAVIVDVPTKRPIQMSITTVHQQSYVIVRVYSEGLVGVGEGGSVGGPVWSAECAETIKIIVERYLAPHLLGTDAFNVSGALQTMARAVTGNASAKAAVEMALLDLKARALGVSIAELLGGPLRSAIPIAWTLASGDTKRDLDSAVEMIERRRHNRFKVKLGFRSPQDDLIHMEALSNSLGSKAYLRVDVNQAWDEQVASVYIPELEALGVELIEQPVGRENTQALRRLSDNNRVAIMADESLSTLASAFDLARDRSVDVFSLKLCNMGGVSATQKIAAVAEASGIASYGGTMLDSTIGTSVALQLYSTVPSLPFGCELIGPFVLADTLSHEPLEIRDYELQVPTGVGHGMTLDEDKVRQYARVS", "length": 370, "reference_go_mf": ["GO:0018850", "GO:0030145", "GO:0018849"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_65dece1f11dfc3f3ec80"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_349_1e3v_assembly1", "enzyme_name": "delta 5-3-ketosteroid isomerase", "ec": ["5.3.3.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P07445", "alignment_score": 256.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 129], "sequence": "MNLPTAQEVQGLMARYIELVDVGDIEAIVQMYADDATVEDPFGQPPIHGREQIAAFYRQGLGGGKVRACLTGPVRASHNGCGAMPFRVEMVWNGQPCALDVIDVMRFDEHGRIQTMQAYWSEVNLSVREPQ", "length": 131, "reference_go_mf": ["GO:0004769"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_a0e05a1043ddefae2891"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_34_1mpy_assembly1", "enzyme_name": "catechol 2,3-dioxygenase", "ec": ["1.13.11.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P06622", "alignment_score": 614.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 307], "sequence": "MNKGVMRPGHVQLRVLDMSKALEHYVELLGLIEMDRDDQGRVYLKAWTEVDKFSLVLREADEPGMDFMGFKVVDEDALRQLERDLMAYGCAVEQLPAGELNSCGRRVRFQAPSGHHFELYADKEYTGKWGLNDVNPEAWPRDLKGMAAVRFDHALMYGDELPATYDLFTKVLGFYLAEQVLDENGTRVAQFLSLSTKAHDVAFIHHPEKGRLHHVSFHLETWEDLLRAADLISMTDTSIDIGPTRHGLTHGKTIYFFDPSGNRNEVFCGGDYNYPDHKPVTWTTDQLGKAIFYHDRILNERFMTVLT", "length": 307, "reference_go_mf": ["GO:0018577", "GO:0008198"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_9b7abb0c36ee625d32bc"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_350_1h3i_assembly1", "enzyme_name": "histone-lysine N-methyltransferase (SET7/9 subfamily)", "ec": ["2.1.1.43"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q8WTS6", "alignment_score": 586.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [51, 344], "sequence": "MDSDDEMVEEAVEGHLDDDGLPHGFCTVTYSSTDRFEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQGQGVYTYEDGGVLQGTYVDGELNGPAQEYDTDGRLIFKGQYKDNIRHGVCWIYYPDGGSLVGEVNEDGEMTGEKIAYVYPDERTALYGKFIDGEMIEGKLATLMSTEEGRPHFELMPGNSVYHFDKSTSSCISTNALLPDPYESERVYVAESLISSAGEGLFSKVAVGPNTVMSFYNGVRITHQEVDSRDWALNGNTLSLDEETVIDVPEPYNHVSKYCASLGHKANHSFTPNCIYDMFVHPRFGPIKCIRTLRAVEADEELTVAYGYDHSPPGKSGPEAPEWYQVELKAFQATQQK", "length": 366, "reference_go_mf": ["GO:0140938", "GO:0140945", "GO:0042054", "GO:0002039", "GO:0016279"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_31d1c12c4007b059f95e"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_351_1snz_assembly1", "enzyme_name": "aldose 1-epimerase", "ec": ["5.1.3.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q96C23", "alignment_score": 684.0, "observed_coverage": 0.9941860465116279, "aligned_identity": 1.0, "canonical_span": [0, 342], "sequence": "MASVTRAVFGELPSGGGTVEKFQLQSDLLRVDIISWGCTITALEVKDRQGRASDVVLGFAELEGYLQKQPYFGAVIGRVANRIAKGTFKVDGKEYHLAINKEPNSLHGGVRGFDKVLWTPRVLSNGVQFSRISPDGEEGYPGELKVWVTYTLDGGELIVNYRAQASQATPVNLTNHSYFNLAGQASPNINDHEVTIEADTYLPVDETLIPTGEVAPVQGTAFDLRKPVELGKHLQDFHLNGFDHNFCLKGSKEKHFCARVHHAASGRVLEVYTTQPGVQFYTGNFLDGTLKGKNGAVYPKHSGFCLETQNWPDAVNQPRFPPVLLRPGEEYDHTTWFKFSVA", "length": 342, "reference_go_mf": ["GO:0004034", "GO:0030246"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_02ca901bb61b9a8f7e38"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_353_1mbb_assembly1", "enzyme_name": "UDP-N-acetylenolpyruvylglucosamine reductase (MurB)", "ec": ["1.3.1.98"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P08373", "alignment_score": 680.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [2, 342], "sequence": "MNHSLKPWNTFGIDHNAQHIVCAEDEQQLLNAWQYATAEGQPVLILGEGSNVLFLEDYRGTVIINRIKGIEIHDEPDAWYLHVGAGENWHRLVKYTLQEGMPGLENLALIPGCVGSSPIQNIGAYGVELQRVCAYVDSVELATGKQVRLTAKECRFGYRDSIFKHEYQDRFAIVAVGLRLPKEWQPVLTYGDLTRLDPTTVTPQQVFNAVCHMRTTKLPDPKVNGNAGSFFKNPVVSAETAKALLSQFPTAPNYPQADGSVKLAAGWLIDQCQLKGMQIGGAAVHRQQALVLINEDNAKSEDVVQLAHHVRQKVGEKFNVWLEPEVRFIGASGEVSAVETIS", "length": 342, "reference_go_mf": ["GO:0071949", "GO:0050660", "GO:0008762"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_f5a2b7a2bc13b96cafa0"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_354_1coy_assembly1", "enzyme_name": "cholesterol oxidase (GMC type)", "ec": ["1.1.3.6"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P22637", "alignment_score": 989.5, "observed_coverage": 1.0, "aligned_identity": 0.9960079840319361, "canonical_span": [48, 551], "sequence": "MTDSRANRADATRGVASVSRRRFLAGAGLTAGAIALSSMSTSASAAPSRTLADGDRVPALVIGSGYGGAVAALRLTQAGIPTQIVEMGRSWDTPGSDGKIFCGMLNPDKRSMWLADKTDQPVSNFMGFGINKSIDRYVGVLDSERFSGIKVYQGRGVGGGSLVNGGMAVTPKRNYFEEILPSVDSNEMYNKYFPRANTGLGVNNIDQAWFESTEWYKFARTGRKTAQRSGFTTAFVPNVYDFEYMKKEAAGQVTKSGLGGEVIYGNNAGKKSLDKTYLAQAAATGKLTITTLHRVTKVAPATGSGYSVTMEQIDEQGNVVATKVVTADRVFFAAGSVGTSKLLVSMKAQGHLPNLSSQVGEGWGNNGNIMVGRANHMWDATGSKQATIPTMGIDNWADPTAPIFAEIAPLPAGLETYVSLYLAITKNPERARFQFNSGTGKVDLTWAQSQNQKGIDMAKKVFDKINQKEGTIYRTDLFGVYFKTWGDDFTYHPLGGVLLNKATDNFGRLPEYPGLYVVDGSLVPGNVGVNPFVTITRLAERNMDKIISSDIQ", "length": 552, "reference_go_mf": ["GO:0016995", "GO:0050660", "GO:0004769"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_7aa0891d055f4cac569a"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_355_1cgk_assembly1", "enzyme_name": "naringenin-chalcone synthase", "ec": ["2.3.1.74"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P30074", "alignment_score": 766.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [2, 389], "sequence": "MVSVSEIRKAQRAEGPATILAIGTANPANCVEQSTYPDFYFKITNSEHKTELKEKFQRMCDKSMIKRRYMYLTEEILKENPNVCEYMAPSLDARQDMVVVEVPRLGKEAAVKAIKEWGQPKSKITHLIVCTTSGVDMPGADYQLTKLLGLRPYVKRYMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEVTAVTFRGPSDTHLDSLVGQALFGDGAAALIVGSDPVPEIEKPIFEMVWTAQTIAPDSEGAIDGHLREAGLTFHLLKDVPGIVSKNITKALVEAFEPLGISDYNSIFWIAHPGGPAILDQVEQKLALKPEKMNATREVLSEYGNMSSACVLFILDEMRKKSTQNGLKTTGEGLEWGVLFGFGPGLTIETVVLRSVAI", "length": 389, "reference_go_mf": ["GO:0016210"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_ca814b9ac4de3d12d0f1"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_356_1vzx_assembly1", "enzyme_name": "alpha-1,3-galactosetransferase", "ec": ["2.4.1.87"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P14769", "alignment_score": 571.0, "observed_coverage": 1.0, "aligned_identity": 0.9965156794425087, "canonical_span": [81, 368], "sequence": "MNVKGKVILSMLVVSTVIVVFWEYIHSPEGSLFWINPSRNPEVGGSSIQKGWWLPRWFNNGYHEEDGDINEEKEQRNEDESKLKLSDWFNPFKRPEVVTMTKWKAPVVWEGTYNRAVLDNYYAKQKITVGLTVFAVGRYIEHYLEEFLTSANKHFMVGHPVIFYIMVDDVSRMPLIELGPLRSFKVFKIKPEKRWQDISMMRMKTIGEHIVAHIQHEVDFLFCMDVDQVFQDKFGVETLGESVAQLQAWWYKADPNDFTYERRKESAAYIPFGEGDFYYHAAIFGGTPTQVLNITQECFKGILKDKKNDIEAQWHDESHLNKYFLLNKPTKILSPEYCWDYHIGLPADIKLVKMSWQTKEYNVVRNNV", "length": 368, "reference_go_mf": ["GO:0016757", "GO:0047276"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_a1d4223a15f222fd9b9c"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_357_3thi_assembly1", "enzyme_name": "thiaminase (class 1)", "ec": ["2.5.1.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P45741", "alignment_score": 724.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [38, 400], "sequence": "MSKVKGFIYKPLMVMLALLLVVVSPAGAGAAHSDASSDITLKVAIYPYVPDPARFQAAVLDQWQRQEPGVKLEFTDWDSYSADPPDDLDVFVLDSIFLSHFVDAGYLLPFGSQDIDQAEDVLPFALQGAKRNGEVYGLPQILCTNLLFYRKGDLKIGQVDNIYELYKKIGTSHSEQIPPPQNKGLLINMAGGTTKASMYLEALIDVTGQYTEYDLLPPLDPLNDKVIRGLRLLINMAGEKPSQYVPEDGDAYVRASWFAQGSGRAFIGYSESMMRMGDYAEQVRFKPISSSAGQDIPLFYSDVVSVNSKTAHPELAKKLANVMASADTVEQALRPQADGQYPQYLLPARHQVYEALMQDYPIYSELAQIVNKPSNRVFRLGPEVRTWLKDAKQVLPEALGLTDVSSLAS", "length": 409, "reference_go_mf": ["GO:0050332"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_26833fc01d776fe75d51"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_358_2a5h_assembly1", "enzyme_name": "lysine 2,3-aminomutase", "ec": ["5.4.3.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q9XBQ8", "alignment_score": 748.5, "observed_coverage": 1.0, "aligned_identity": 0.9975, "canonical_span": [2, 411], "sequence": "MINRRYELFKDVSDADWNDWRWQVRNRIETVEELKKYIPLTKEEEEGVAQCVKSLRMAITPYYLSLIDPNDPNDPVRKQAIPTALELNKAAADLEDPLHEDTDSPVPGLTHRYPDRVLLLITDMCSMYCRHCTRRRFAGQSDDSMPMERIDKAIDYIRNTPQVRDVLLSGGDALLVSDETLEYIIAKLREIPHVEIVRIGSRTPVVLPQRITPELVNMLKKYHPVWLNTHFNHPNEITEESTRACQLLADAGVPLGNQSVLLRGVNDCVHVMKELVNKLVKIRVRPYYIYQCDLSLGLEHFRTPVSKGIEIIEGLRGHTSGYCVPTFVVDAPGGGGKTPVMPNYVISQSHDKVILRNFEGVITTYSEPINYTPGCNCDVCTGKKKVHKVGVAGLLNGEGMALEPVGLERNKRHVQE", "length": 416, "reference_go_mf": ["GO:0051536", "GO:0050066"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_421b5bfd4d954e635fa6"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_359_1f9z_assembly1", "enzyme_name": "lactoglutathione lyase", "ec": ["4.4.1.5"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0AC81", "alignment_score": 252.0, "observed_coverage": 0.984375, "aligned_identity": 1.0, "canonical_span": [0, 126], "sequence": "MRLLHTMLRVGDLQRSIDFYTKVLGMKLLRTSENPEYKYSLAFVGYGPETEEAVIELTYNWGVDKYELGTAYGHIALSVDNAAEACEKIRQNGGNVTREAGPVKGGTTVIAFVEDPDGYKIELIEEKDAGRGLGN", "length": 135, "reference_go_mf": ["GO:0004462", "GO:0016151", "GO:0042803"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_c8203a05674787d2d3cc"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P0AC81", "alignment_score": 252.0, "observed_coverage": 0.984375, "aligned_identity": 1.0, "canonical_span": [0, 126], "sequence": "MRLLHTMLRVGDLQRSIDFYTKVLGMKLLRTSENPEYKYSLAFVGYGPETEEAVIELTYNWGVDKYELGTAYGHIALSVDNAAEACEKIRQNGGNVTREAGPVKGGTTVIAFVEDPDGYKIELIEEKDAGRGLGN", "length": 135, "reference_go_mf": ["GO:0004462", "GO:0016151", "GO:0042803"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_c8203a05674787d2d3cc"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_35_2phk_assembly1", "enzyme_name": "phosphorylase kinase", "ec": ["2.7.11.19"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00518", "alignment_score": 554.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [14, 291], "sequence": "MTRDAALPGSHSTHGFYENYEPKEILGRGVSSVVRRCIHKPTCKEYAVKIIDVTGGGSFSAEEVQELREATLKEVDILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKKGELFDYLTEKVTLSEKETRKIMRALLEVICALHKLNIVHRDLKPENILLDDDMNIKLTDFGFSCQLDPGEKLREVCGTPSYLAPEIIECSMNDNHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSDTVKDLVSRFLVVQPQKRYTAEEALAHPFFQQYVVEEVRHFSPRGKFKVICLTVLASVRIYYQYRRVKPVTREIVIRDPYALRPLRRLIDAYAFRIYGHWVKKGQQQNRAALFENTPKAVLFSLAEDDY", "length": 387, "reference_go_mf": ["GO:0005524", "GO:0005516", "GO:0004689", "GO:0106310", "GO:0050321"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_045ce70793c070560bee"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_361_3a15_assembly1", "enzyme_name": "aldoxime dehydratase", "ec": ["4.99.1.5"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q76K71", "alignment_score": 706.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 353], "sequence": "MESAIGEHLQCPRTLTRRVPDTYTPPFPMWVGRADDALQQVVMGYLGVQFRDEDQRPAALQAMRDIVAGFDLPDGPAHHDLTHHIDNQGYENLIVVGYWKDVSSQHRWSTSTPIASWWESEDRLSDGLGFFREIVAPRAEQFETLYAFQEDLPGVGAVMDGISGEINEHGYWGSMRERFPISQTDWMQASGELRVIAGDPAVGGRVVVRGHDNIALIRSGQDWADAEADERSLYLDEILPTLQSGMDFLRDNGPAVGCYSNRFVRNIDIDGNFLDLSYNIGHWASLDQLERWSESHPTHLRIFTTFFRVAAGLSKLRLYHEVSVFDAADQLYEYINCHPGTGMLRDAVTIAEH", "length": 353, "reference_go_mf": ["GO:0034013"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_48003c95d4d52340df00"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_362_1d6o_assembly1", "enzyme_name": "prolyl cis-trans isomerase (FKBP-type)", "ec": ["5.2.1.8"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P62942", "alignment_score": 214.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 108], "sequence": "MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELLKLE", "length": 108, "reference_go_mf": ["GO:0070697", "GO:0005246", "GO:0005528", "GO:0070411", "GO:0005527", "GO:0003755", "GO:0030547", "GO:0005160", "GO:0044325", "GO:0034713"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_7c2c9a4005a08f9f8ed2"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_363_1grc_assembly1", "enzyme_name": "glycinamide ribonucleotide transformylase", "ec": ["2.1.2.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P08179", "alignment_score": 372.5, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 209], "sequence": "MNIVVLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKADAFGLERARQAGIATHTLIASAFDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTHRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLVISWFADGRLKMHENAAWLDGQRLPPQGYAADE", "length": 212, "reference_go_mf": ["GO:0004644"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_a0b26cb92fa1ad75fb4a"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_364_2tps_assembly1", "enzyme_name": "thiamine phosphate synthase", "ec": ["2.5.1.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P39594", "alignment_score": 444.0, "observed_coverage": 0.9823008849557522, "aligned_identity": 1.0, "canonical_span": [0, 222], "sequence": "MTRISREMMKELLSVYFIMGSNNTKADPVTVVQKALKGGATLYQFREKGGDALTGEARIKFAEKAQAACREAGVPFIVNDDVELALNLKADGIHIGQEDANAKEVRAAIGDMILGVSAHTMSEVKQAEEDGADYVGLGPIYPTETKKDTRAVQGVSLIEAVRRQGISIPIVGIGGITIDNAAPVIQAGADGVSMISAISQAEDPESAARKFREEIQTYKTGR", "length": 222, "reference_go_mf": ["GO:0000287", "GO:0004789"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_66ed73def66ad19af5eb"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_365_1pfk_assembly1", "enzyme_name": "Phosphofructokinase I", "ec": ["2.7.1.11"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0A796", "alignment_score": 640.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 320], "sequence": "MIKKIGVLTSGGDAPGMNAAIRGVVRSALTEGLEVMGIYDGYLGLYEDRMVQLDRYSVSDMINRGGTFLGSARFPEFRDENIRAVAIENLKKRGIDALVVIGGDGSYMGAMRLTEMGFPCIGLPGTIDNDIKGTDYTIGFFTALSTVVEAIDRLRDTSSSHQRISVVEVMGRYCGDLTLAAAIAGGCEFVVVPEVEFSREDLVNEIKAGIAKGKKHAIVAITEHMCDVDELAHFIEKETGRETRATVLGHIQRGGSPVPYDRILASRMGAYAIDLLLAGYGGRCVGIQNEQLVHHDIIDAIENMKRPFKGDWLDCAKKLY", "length": 320, "reference_go_mf": ["GO:0003872", "GO:0005524", "GO:0070095", "GO:0019003", "GO:0042802", "GO:0000287", "GO:0032553"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_b3f55c0dc962540433ca"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_366_1ecl_assembly1", "enzyme_name": "DNA topoisomerase I (type 1A)", "ec": ["5.6.2.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P06612", "alignment_score": 1069.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 590], "sequence": "MGKALVIVESPAKAKTINKYLGSDYVVKSSVGHIRDLPTSGSAAKKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWEAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFNKPGELNIDRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEVDASTTTPSGEALALQVTHQNDKPFRPVNKEQTQAAVSLLEKARYSVLEREDKPTTSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNMVRGYISDNFGKKYLPESPNQYASKENSQEAHEAIRPSDVNVMAESLKDMEADAQKLYQLIWRQFVACQMTPAKYDSTTLTVGAGDFRLKARGRILRFDGWTKVMPALRKGDEDRILPAVNKGDALTLVELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMENSLDQVANHEAEWKAVLDHFFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALPPKERCKTTINLVPENEVLNVLEGEDAETNALRAKRRCPKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNEECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPEGNKTMVRFSRKTKQQYVSSEKDGKATGWSAFYVDGKWVEGKK", "length": 865, "reference_go_mf": ["GO:0003677", "GO:0003916", "GO:0003917", "GO:0140226"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_d0b68b903f1bec5cf59a"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_367_2iht_assembly1", "enzyme_name": "N(2)-(2-carboxyethyl)arginine synthase", "ec": ["2.5.1.66"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q9LCV9", "alignment_score": 1033.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [10, 573], "sequence": "MSRVSTAPSGKPTAAHALLSRLRDHGVGKVFGVVGREAASILFDEVEGIDFVLTRHEFTAGVAADVLARITGRPQACWATLGPGMTNLSTGIATSVLDRSPVIALAAQSESHDIFPNDTHQCLDSVAIVAPMSKYAVELQRPHEITDLVDSAVNAAMTEPVGPSFISLPVDLLGSSEGIDTTVPNPPANTPAKPVGVVADGWQKAADQAAALLAEAKHPVLVVGAAAIRSGAVPAIRALAERLNIPVITTYIAKGVLPVGHELNYGAVTGYMDGILNFPALQTMFAPVDLVLTVGYDYAEDLRPSMWQKGIEKKTVRISPTVNPIPRVYRPDVDVVTDVLAFVEHFETATASFGAKQRHDIEPLRARIAEFLADPETYEDGMRVHQVIDSMNTVMEEAAEPGEGTIVSDIGFFRHYGVLFARADQPFGFLTSAGCSSFGYGIPAAIGAQMARPDQPTFLIAGDGGFHSNSSDLETIARLNLPIVTVVVNNDTNGLIELYQNIGHHRSHDPAVKFGGVDFVALAEANGVDATRATNREELLAALRKGAELGRPFLIEVPVNYDFQPGGFGALSI", "length": 573, "reference_go_mf": ["GO:0003984", "GO:0050660", "GO:0000287", "GO:0033848", "GO:0030976"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_ce771b5795bb478942a5"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "Q9LCV9", "alignment_score": 1035.5, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [10, 573], "sequence": "MSRVSTAPSGKPTAAHALLSRLRDHGVGKVFGVVGREAASILFDEVEGIDFVLTRHEFTAGVAADVLARITGRPQACWATLGPGMTNLSTGIATSVLDRSPVIALAAQSESHDIFPNDTHQCLDSVAIVAPMSKYAVELQRPHEITDLVDSAVNAAMTEPVGPSFISLPVDLLGSSEGIDTTVPNPPANTPAKPVGVVADGWQKAADQAAALLAEAKHPVLVVGAAAIRSGAVPAIRALAERLNIPVITTYIAKGVLPVGHELNYGAVTGYMDGILNFPALQTMFAPVDLVLTVGYDYAEDLRPSMWQKGIEKKTVRISPTVNPIPRVYRPDVDVVTDVLAFVEHFETATASFGAKQRHDIEPLRARIAEFLADPETYEDGMRVHQVIDSMNTVMEEAAEPGEGTIVSDIGFFRHYGVLFARADQPFGFLTSAGCSSFGYGIPAAIGAQMARPDQPTFLIAGDGGFHSNSSDLETIARLNLPIVTVVVNNDTNGLIELYQNIGHHRSHDPAVKFGGVDFVALAEANGVDATRATNREELLAALRKGAELGRPFLIEVPVNYDFQPGGFGALSI", "length": 573, "reference_go_mf": ["GO:0003984", "GO:0050660", "GO:0000287", "GO:0033848", "GO:0030976"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_ce771b5795bb478942a5"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_368_1i8t_assembly1", "enzyme_name": "UDP-galactopyranose mutase", "ec": ["5.4.99.9"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P37747", "alignment_score": 734.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 367], "sequence": "MYDYIIVGSGLFGAVCANELKKLNKKVLVIEKRNHIGGNAYTEDCEGIQIHKYGAHIFHTNDKYIWDYVNDLVEFNRFTNSPLAIYKDKLFNLPFNMNTFHQMWGVKDPQEAQNIINAQKKKYGDKVPENLEEQAISLVGEDLYQALIKGYTEKQWGRSAKELPAFIIKRIPVRFTFDNNYFSDRYQGIPVGGYTKLIEKMLEGVDVKLGIDFLKDKDSLASKAHRIIYTGPIDQYFDYRFGALEYRSLKFETERHEFPNFQGNAVINFTDANVPYTRIIEHKHFDYVETKHTVVTKEYPLEWKVGDEPYYPVNDNKNMELFKKYRELASREDKVIFGGRLAEYKYYDMHQVISAALYQVKNIMSTD", "length": 367, "reference_go_mf": ["GO:0050660", "GO:0042803", "GO:0008767"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_780fa5a1733a70b8d70d"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_369_1dlg_assembly2", "enzyme_name": "UDP-N-acetylglucosamine enolpyruvyl transferase", "ec": ["2.5.1.7"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P33038", "alignment_score": 827.0, "observed_coverage": 1.0, "aligned_identity": 0.9976076555023924, "canonical_span": [0, 419], "sequence": "MDKFRVQGPTRLQGEVTISGAKNAALPILFAALLAEEPVEIQNVPKLKDIDTTMKLLTQLGTKVERNGSVWIDASNVNNFSAPYDLVKTMRASIWALGPLVARFGQGQVSLPGGCAIGARPVDLHIFGLEKLGAEIKLEEGYVKASVNGRLKGAHIVMDKVSVGATVTIMSAATLAEGTTIIENAAREPEIVDTANFLVALGAKISGQGTDRITIEGVERLGGGVYRVLPDRIETGTFLVAAAISGGKIVCRNAQPDTLDAVLAKLREAGADIETGEDWISLDMHGKRPKAVTVRTAPHPAFPTDMQAQFTLLNLVAEGTGVITETIFENRFMHVPELIRMGAHAEIESNTVICHGVEKLSGAQVMATDLRASASLVLAGCIAEGTTVVDRIYHIDRGYERIEDKLRALGANIERVKGE", "length": 419, "reference_go_mf": ["GO:0008760"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_279d83f5ab5eb3cfb73a"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_36_1qq5_assembly1", "enzyme_name": "(S)-2-haloacid dehalogenase", "ec": ["3.8.1.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q60099", "alignment_score": 487.0, "observed_coverage": 1.0, "aligned_identity": 0.9959183673469387, "canonical_span": [0, 245], "sequence": "MIKAVVFDAYGTLFDVQSVADATERAYPGRGEYITQVWRQKQLEYSWLRALMGRYADFWGVTREALAYTLGTLGLEPDESFLADMAQAYNRLTPYPDAAQCLAELAPLKRAILSNGAPDMLQALVANAGLTDSFDAVISVDAKRVFKPHPDSYALVEEVLGVTPAEVLFVSSNGFDVGGAKNFGFSVARVARLSQEALARELVSGTIAPLTMFKALRMREETYAEAPDFVVPALGDLPRLVRGMAGAHLAPAV", "length": 253, "reference_go_mf": ["GO:0018784"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_58d2d368ffdd947a362e"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_370_2ybp_assembly1", "enzyme_name": "lysine-specific [histone H3] demethylase", "ec": ["1.14.11.27"], "controls": [{"chain": "A", "status": "reference_overlength", "selected": {"accession": "O75164", "alignment_score": 698.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [6, 355], "sequence": "MASESETLNPSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKPRASYDDIDDLVIPAPIQQLVTGQSGLFTQYNIQKKAMTVREFRKIANSDKYCTPRYSEFEELERKYWKNLTFNPPIYGADVNGTLYEKHVDEWNIGRLRTILDLVEKESGITIEGVNTPYLYFGMWKTSFAWHTEDMDLYSINYLHFGEPKSWYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRHKMTLISPLMLKKYGIPFDKVTQEAGEFMITFPYGYHAGFNHGFNCAESTNFATRRWIEYGKQAVLCSCRKDMVKISMDVFVRKFQPERYKLWKAGKDNTVIDHTLPTPEAAEFLKESELPPRAGNEEECPEEDMEGVEDGEEGDLKTSLAKHRIGTKRHRVCLEIPQEVSQSELFPKEDLSSEQYEMTECPAALAPVRPTHSSVRQVEDGLTFPDYSDSTEVKFEELKNVKLEEEDEEEEQAAAALDLSVNPASVGGRLVFSGSKKKSSSSLGSGSSRDSISSDSETSEPLSCRAQGQTGVLTVHSYAKGDGRVTVGEPCTRKKGSAARSFSERELAEVADEYMFSLEENKKSKGRRQPLSKLPRHHPLVLQECVSDDETSEQLTPEEEAEETEAWAKPLSQLWQNRPPNFEAEKEFNETMAQQAPHCAVCMIFQTYHQVEFGGFNQNCGNASDLAPQKQRTKPLIPEMCFTSTGCSTDINLSTPYLEEDGTSILVSCKKCSVRVHASCYGVPPAKASEDWMCSRCSANALEEDCCLCSLRGGALQRANDDRWVHVSCAVAILEARFVNIAERSPVDVSKIPLPRFKLKCIFCKKRRKRTAGCCVQCSHGRCPTAFHVSCAQAAGVMMQPDDWPFVVFITCFRHKIPNLERAKGALQSITAGQKVISKHKNGRFYQCEVVRLTTETFYEVNFDDGSFSDNLYPEDIVSQDCLQFGPPAEGEVVQVRWTDGQVYGAKFVASHPIQMYQVEFEDGSQLVVKRDDVYTLDEELPKRVKSRLSVASDMRFNEIFTEKEVKQEKKRQRVINSRYREDYIEPALYRAIME", "length": 1064, "reference_go_mf": ["GO:0032452", "GO:0051864", "GO:0140681", "GO:0032454", "GO:0140684", "GO:0140005", "GO:0031625", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_371_1a05_assembly1", "enzyme_name": "3-isopropylmalate dehydrogenase", "ec": ["1.1.1.85"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q56268", "alignment_score": 714.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 357], "sequence": "MKKIAIFAGDGIGPEIVAAARQVLDAVDQAAHLGLRCTEGLVGGAALDASDDPLPAASLQLAMAADAVILGAVGGPRWDAYPPAKRPEQGLLRLRKGLDLYANLRPAQIFPQLLDASPLRPELVRDVDILVVRELTGDIYFGQPRGLEVIDGKRRGFNTMVYDEDEIRRIAHVAFRAAQGRRKQLCSVDKANVLETTRLWREVVTEVARDYPDVRLSHMYVDNAAMQLIRAPAQFDVLLTGNMFGDILSDEASQLTGSIGMLPSASLGEGRAMYEPIHGSAPDIAGQDKANPLATILSVAMMLRHSLNAEPWAQRVEAAVQRVLDQGLRTADIAAPGTPVIGTKAMGAAVVNALNLKD", "length": 358, "reference_go_mf": ["GO:0003862", "GO:0000287", "GO:0051287"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_9b6860ab316e12e51007"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "Q56268", "alignment_score": 714.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 357], "sequence": "MKKIAIFAGDGIGPEIVAAARQVLDAVDQAAHLGLRCTEGLVGGAALDASDDPLPAASLQLAMAADAVILGAVGGPRWDAYPPAKRPEQGLLRLRKGLDLYANLRPAQIFPQLLDASPLRPELVRDVDILVVRELTGDIYFGQPRGLEVIDGKRRGFNTMVYDEDEIRRIAHVAFRAAQGRRKQLCSVDKANVLETTRLWREVVTEVARDYPDVRLSHMYVDNAAMQLIRAPAQFDVLLTGNMFGDILSDEASQLTGSIGMLPSASLGEGRAMYEPIHGSAPDIAGQDKANPLATILSVAMMLRHSLNAEPWAQRVEAAVQRVLDQGLRTADIAAPGTPVIGTKAMGAAVVNALNLKD", "length": 358, "reference_go_mf": ["GO:0003862", "GO:0000287", "GO:0051287"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_9b6860ab316e12e51007"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_373_1qi9_assembly1", "enzyme_name": "Vanadium-dependent bromoperoxidase (organic sulfide oxidation)", "ec": ["1.11.1.18"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P81701", "alignment_score": 1110.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 556], "sequence": "QTCSTSDDADDPTPPNERDDEAFASRVAAAKRELEGTGTVCQINNGETDLAAKFHKSLPHDDLGQVDADAFAALEDCILNGDLSICEDVPVGNSEGDPVGRLVNPTAAFAIDISGPAFSATTIPPVPTLPSPELAAQLAEVYWMALARDVPFMQYGTDDITVTAAANLAGMEGFPNLDAVSIGSDGTVDPLSQLFRATFVGVETGPFISQLLVNSFTIDSITVEPKQETFAPDVNYMVDFDEWLNIQNGGPPAGPELLDDELRFVRNARDLARVTFTDNINTEAYRGALILLGLDAFNRAGVNGPFIDIDRQAGFVNFGISHYFRLIGAAELAQRSSWYQKWQVHRFARPEALGGTLHLTIKGELNADFDLSLLENAELLKRVAAINAAQNPNNEVTYLLPQAIQEGSPTHPSYPSGHATQNGAFATVLKALIGLDRGGDCYPDPVYPDDDGLKLIDFRGSCLTFEGEINKLAVNVAFGRQMLGIHYRFDGIQGLLLGETITVRTLHQELMTFAEESTFEFRLFTGEVIKLFQDGTFTIDGFKCPGLVYTGVENCVS", "length": 557, "reference_go_mf": ["GO:0019806"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_25a41147978eec7f04ab"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_374_1qi9_assembly1", "enzyme_name": "Vanadium-dependent bromoperoxidase (organic molecule bromination)", "ec": ["1.11.1.18"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P81701", "alignment_score": 1110.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 556], "sequence": "QTCSTSDDADDPTPPNERDDEAFASRVAAAKRELEGTGTVCQINNGETDLAAKFHKSLPHDDLGQVDADAFAALEDCILNGDLSICEDVPVGNSEGDPVGRLVNPTAAFAIDISGPAFSATTIPPVPTLPSPELAAQLAEVYWMALARDVPFMQYGTDDITVTAAANLAGMEGFPNLDAVSIGSDGTVDPLSQLFRATFVGVETGPFISQLLVNSFTIDSITVEPKQETFAPDVNYMVDFDEWLNIQNGGPPAGPELLDDELRFVRNARDLARVTFTDNINTEAYRGALILLGLDAFNRAGVNGPFIDIDRQAGFVNFGISHYFRLIGAAELAQRSSWYQKWQVHRFARPEALGGTLHLTIKGELNADFDLSLLENAELLKRVAAINAAQNPNNEVTYLLPQAIQEGSPTHPSYPSGHATQNGAFATVLKALIGLDRGGDCYPDPVYPDDDGLKLIDFRGSCLTFEGEINKLAVNVAFGRQMLGIHYRFDGIQGLLLGETITVRTLHQELMTFAEESTFEFRLFTGEVIKLFQDGTFTIDGFKCPGLVYTGVENCVS", "length": 557, "reference_go_mf": ["GO:0019806"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_25a41147978eec7f04ab"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_375_4ts9_assembly1", "enzyme_name": "Purine nucleoside phosphorylase DeoD-type", "ec": ["2.4.2.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0ABP8", "alignment_score": 471.0, "observed_coverage": 1.0, "aligned_identity": 0.9957805907172996, "canonical_span": [1, 238], "sequence": "MATPHINAEMGDFADVVLMPGDPLRAKYIAETFLEDAREVNNVRGMLGFTGTYKGRKISVMGHGMGIPSCSIYTKELITDFGVKKIIRVGSCGAVLPHVKLRDVVIGMGACTDSKVNRIRFKDHDFAAIADFDMVRNAVDAAKALGIDARVGNLFSADLFYSPDGEMFDVMEKYGILGVEMEAAGIYGVAAEFGAKALTICTVSDHIRTHEQTTAAERQTTFNDMIKIALESVLLGDKE", "length": 239, "reference_go_mf": ["GO:0047975", "GO:0042802", "GO:0004731"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_b01744a3a12146493ee3"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P0ABP8", "alignment_score": 471.0, "observed_coverage": 1.0, "aligned_identity": 0.9957805907172996, "canonical_span": [1, 238], "sequence": "MATPHINAEMGDFADVVLMPGDPLRAKYIAETFLEDAREVNNVRGMLGFTGTYKGRKISVMGHGMGIPSCSIYTKELITDFGVKKIIRVGSCGAVLPHVKLRDVVIGMGACTDSKVNRIRFKDHDFAAIADFDMVRNAVDAAKALGIDARVGNLFSADLFYSPDGEMFDVMEKYGILGVEMEAAGIYGVAAEFGAKALTICTVSDHIRTHEQTTAAERQTTFNDMIKIALESVLLGDKE", "length": 239, "reference_go_mf": ["GO:0047975", "GO:0042802", "GO:0004731"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_b01744a3a12146493ee3"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_376_1a4l_assembly1", "enzyme_name": "adenosine deaminase", "ec": ["3.5.4.4"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P03958", "alignment_score": 698.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [3, 352], "sequence": "MAQTPAFNKPKVELHVHLDGAIKPETILYFGKKRGIALPADTVEELRNIIGMDKPLSLPGFLAKFDYYMPVIAGCREAIKRIAYEFVEMKAKEGVVYVEVRYSPHLLANSKVDPMPWNQTEGDVTPDDVVDLVNQGLQEGEQAFGIKVRSILCCMRHQPSWSLEVLELCKKYNQKTVVAMDLAGDETIEGSSLFPGHVEAYEGAVKNGIHRTVHAGEVGSPEVVREAVDILKTERVGHGYHTIEDEALYNRLLKENMHFEVCPWSSYLTGAWDPKTTHAVVRFKNDKANYSLNTDDPLIFKSTLDTDYQMTKKDMGFTEEEFKRLNINAAKSSFLPEEEKKELLERLYREYQ", "length": 352, "reference_go_mf": ["GO:0046936", "GO:0004000", "GO:0019239", "GO:0001883", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_ae372e92c280c531aebb"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_377_1r0m_assembly1", "enzyme_name": "N-succinylamino acid racemase", "ec": ["5.1.1.10"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q9RYA6", "alignment_score": 694.5, "observed_coverage": 1.0, "aligned_identity": 0.9861111111111112, "canonical_span": [5, 375], "sequence": "MAHTGRMFKIEAAEIVVARLPLKFRFETSFGVQTHKVVPLLILHGEGVQGVAEGTMEARPMYREETIAGALDLLRGTFLPAILGQTFANPEAVADALGSYRGNRMARAMVEMAAWDLWARTLGVPLGTLLGGHKEQVEVGVSLGIQAGEQATVDLVRKHVEQGYRRIKLKIKPGWDVQPVRATREAFPDIRLTVDANSAYTLADAGRLRQLDEYDLTYIEQPLAWDDLVDHAELARRIRTPLCLDESVASAADARKALALGAGGVINLKVARVGGHAESRRVHDVAQSFGAPVWCGGMLESGIGRAHNIHLSTLPNFRLPGDTSSASRYWERDLIQEPLEAVDGLMPVPQGPGTGVTLDREFLATVTEAQEEHRA", "length": 375, "reference_go_mf": ["GO:0047661", "GO:0043748"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_a6ffc3f112129082fa66"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_378_1mok_assembly1", "enzyme_name": "2-oxopropyl-CoM reductase, carboxylating", "ec": ["1.8.1.5"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q56839", "alignment_score": 1044.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 523], "sequence": "MKVWNARNDHLTINQWATRIDEILEAPDGGEVIYNVDENDPREYDAIFIGGGAAGRFGSAYLRAMGGRQLIVDRWPFLGGSCPHNACVPHHLFSDCAAELMLARTFSGQYWFPDMTEKVVGIKEVVDLFRAGRNGPHGIMNFQSKEQLNLEYILNCPAKVIDNHTVEAAGKVFKAKNLILAVGAGPGTLDVPGVNAKGVFDHATLVEELDYEPGSTVVVVGGSKTAVEYGCFFNATGRRTVMLVRTEPLKLIKDNETRAYVLDRMKEQGMEIISGSNVTRIEEDANGRVQAVVAMTPNGEMRIETDFVFLGLGEQPRSAELAKILGLDLGPKGEVLVNEYLQTSVPNVYAVGDLIGGPMEMFKARKSGCYAARNVMGEKISYTPKNYPDFLHTHYEVSFLGMGEEEARAAGHEIVTIKMPPDTENGLNVALPASDRTMLYAFGKGTAHMSGFQKIVIDAKTRKVLGAHHVGYGAKDAFQYLNVLIKQGLTVDELGDMDELFLNPTHFIQLSRLRAGSKNLVSL", "length": 523, "reference_go_mf": ["GO:0050628"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_430df05a593a4837d1ed"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "Q56839", "alignment_score": 1044.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 523], "sequence": "MKVWNARNDHLTINQWATRIDEILEAPDGGEVIYNVDENDPREYDAIFIGGGAAGRFGSAYLRAMGGRQLIVDRWPFLGGSCPHNACVPHHLFSDCAAELMLARTFSGQYWFPDMTEKVVGIKEVVDLFRAGRNGPHGIMNFQSKEQLNLEYILNCPAKVIDNHTVEAAGKVFKAKNLILAVGAGPGTLDVPGVNAKGVFDHATLVEELDYEPGSTVVVVGGSKTAVEYGCFFNATGRRTVMLVRTEPLKLIKDNETRAYVLDRMKEQGMEIISGSNVTRIEEDANGRVQAVVAMTPNGEMRIETDFVFLGLGEQPRSAELAKILGLDLGPKGEVLVNEYLQTSVPNVYAVGDLIGGPMEMFKARKSGCYAARNVMGEKISYTPKNYPDFLHTHYEVSFLGMGEEEARAAGHEIVTIKMPPDTENGLNVALPASDRTMLYAFGKGTAHMSGFQKIVIDAKTRKVLGAHHVGYGAKDAFQYLNVLIKQGLTVDELGDMDELFLNPTHFIQLSRLRAGSKNLVSL", "length": 523, "reference_go_mf": ["GO:0050628"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_430df05a593a4837d1ed"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_379_1a16_assembly1", "enzyme_name": "Xaa-Pro aminopeptidase", "ec": ["3.4.11.9"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P15034", "alignment_score": 872.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 441], "sequence": "MSEISRQEFQRRRQALVEQMQPGSAALIFAAPEVTRSADSEYPYRQNSDFWYFTGFNEPEAVLVLIKSDDTHNHSVLFNRVRDLTAEIWFGRRLGQDAAPEKLGVDRALAFSEINQQLYQLLNGLDVVYHAQGEYAYADVIVNSALEKLRKGSRQNLTAPATMIDWRPVVHEMRLFKSPEEIAVLRRAGEITAMAHTRAMEKCRPGMFEYHLEGEIHHEFNRHGARYPSYNTIVGSGENGCILHYTENECEMRDGDLVLIDAGCEYKGYAGDITRTFPVNGKFTQAQREIYDIVLESLETSLRLYRPGTSILEVTGEVVRIMVSGLVKLGILKGDVDELIAQNAHRPFFMHGLSHWLGLDVHDVGVYGQDRSRILEPGMVLTVEPGLYIAPDAEVPEQYRGIGIRIEDDIVITETGNENLTASVVKKPEEIEALMVAARKQ", "length": 441, "reference_go_mf": ["GO:0004177", "GO:0042802", "GO:0030145", "GO:0070006", "GO:0008235"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_f99fa405f75c7d026b5b"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P15034", "alignment_score": 872.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 441], "sequence": "MSEISRQEFQRRRQALVEQMQPGSAALIFAAPEVTRSADSEYPYRQNSDFWYFTGFNEPEAVLVLIKSDDTHNHSVLFNRVRDLTAEIWFGRRLGQDAAPEKLGVDRALAFSEINQQLYQLLNGLDVVYHAQGEYAYADVIVNSALEKLRKGSRQNLTAPATMIDWRPVVHEMRLFKSPEEIAVLRRAGEITAMAHTRAMEKCRPGMFEYHLEGEIHHEFNRHGARYPSYNTIVGSGENGCILHYTENECEMRDGDLVLIDAGCEYKGYAGDITRTFPVNGKFTQAQREIYDIVLESLETSLRLYRPGTSILEVTGEVVRIMVSGLVKLGILKGDVDELIAQNAHRPFFMHGLSHWLGLDVHDVGVYGQDRSRILEPGMVLTVEPGLYIAPDAEVPEQYRGIGIRIEDDIVITETGNENLTASVVKKPEEIEALMVAARKQ", "length": 441, "reference_go_mf": ["GO:0004177", "GO:0042802", "GO:0030145", "GO:0070006", "GO:0008235"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_f99fa405f75c7d026b5b"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_37_5cox_assembly1", "enzyme_name": "prostaglandin-endoperoxide synthase", "ec": ["1.14.99.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q05769", "alignment_score": 1098.0, "observed_coverage": 1.0, "aligned_identity": 0.9963768115942029, "canonical_span": [17, 569], "sequence": "MLFRAVLLCAALGLSQAANPCCSNPCQNRGECMSTGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPNTVHYILTHFKGVWNIVNNIPFLRSLIMKYVLTSRSYLIDSPPTYNVHYGYKSWEAFSNLSYYTRALPPVADDCPTPMGVKGNKELPDSKEVLEKVLLRREFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPGFTRGLGHGVDLNHIYGETLDRQHKLRLFKDGKLKYQVIGGEVYPPTVKDTQVEMIYPPHIPENLQFAVGQEVFGLVPGLMMYATIWLREHNRVCDILKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIASEFNTLYHWHPLLPDTFNIEDQEYSFKQFLYNNSILLEHGLTQFVESFTRQIAGRVAGGRNVPIAVQAVAKASIDQSREMKYQSLNEYRKRFSLKPYTSFEELTGEKEMAAELKALYSDIDVMELYPALLVEKPRPDAIFGETMVELGAPFSLKGLMGNPICSPQYWKPSTFGGEVGFKIINTASIQSLICNNVKGCPFTSFNVQDPQPTKTATINASASHSRLDDINPTVLIKRRSTEL", "length": 604, "reference_go_mf": ["GO:0019899", "GO:0020037", "GO:0016705", "GO:0016701", "GO:0016702", "GO:0004601", "GO:0004666", "GO:0042803"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_9e80e7fc4245e685ef4e"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_380_1nlu_assembly1", "enzyme_name": "sedolisin", "ec": ["3.4.21.100"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P42790", "alignment_score": 736.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [217, 585], "sequence": "MKSSAAKQTVLCLNRYAVVALPLAIASFAAFGASPASTLWAPTDTKAFVTPAQVEARSAAPLLELAAGETAHIVVSLKLRDEAQLKQLAQAVNQPGNAQFGKFLKRRQFLSQFAPTEAQVQAVVAHLRKNGFVNIHVVPNRLLISADGSAGAVKAAFNTPLVRYQLNGKAGYANTAPAQVPQDLGEIVGSVLGLQNVTRAHPMLKVGERSAAKTLAAGTAKGHNPTEFPTIYDASSAPTAANTTVGIITIGGVSQTLQDLQQFTSANGLASVNTQTIQTGSSNGDYSDDQQGQGEWDLDSQSIVGSAGGAVQQLLFYMADQSASGNTGLTQAFNQAVSDNVAKVINVSLGWCEADANADGTLQAEDRIFATAAAQGQTFSVSSGDEGVYECNNRGYPDGSTYSVSWPASSPNVIAVGGTTLYTTSAGAYSNETVWNEGLDSNGKLWATGGGYSVYESKPSWQSVVSGTPGRRLLPDISFDAAQGTGALIYNYGQLQQIGGTSLASPIFVGLWARLQSANSNSLGFPAASFYSAISSTPSLVHDVKSGNNGYGGYGYNAGTGWDYPTGWGSLDIAKLSAYIRSNGFGH", "length": 587, "reference_go_mf": ["GO:0004252", "GO:0008240"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_2cfb1855431a92a1541c"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_381_1tde_assembly1", "enzyme_name": "Thioredoxin reductase", "ec": ["1.8.1.9"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0A9P4", "alignment_score": 632.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 317], "sequence": "MGTTKHSKLLILGSGPAGYTAAVYAARANLQPVLITGMEKGGQLTTTTEVENWPGDPNDLTGPLLMERMHEHATKFETEIIFDHINKVDLQNRPFRLNGDNGEYTCDALIIATGASARYLGLPSEEAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVEEALYLSNIASEVHLIHRRDGFRAEKILIKRLMDKVENGNIILHTNRTLEEVTGDQMGVTGVRLRDTQNSDNIESLDVAGLFVAIGHSPNTAIFEGQLELENGYIKVQSGIHGNATQTSIPGVFAAGDVMDHIYRQAITSAGTGCMAALDAERYLDGLADAK", "length": 321, "reference_go_mf": ["GO:0050660", "GO:0004791"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_8970d365802ea67e1bb6"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_383_1a50_assembly1", "enzyme_name": "tryptophan synthase", "ec": ["4.2.1.20"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00929", "alignment_score": 511.5, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 267], "sequence": "MERYENLFAQLNDRREGAFVPFVTLGDPGIEQSLKIIDTLIDAGADALELGVPFSDPLADGPTIQNANLRAFAAGVTPAQCFEMLALIREKHPTIPIGLLMYANLVFNNGIDAFYARCEQVGVDSVLVADVPVEESAPFRQAALRHNIAPIFICPPNADDDLLRQVASYGRGYTYLLSRSGVTGAENRGALPLHHLIEKLKEYHAAPALQGFGISSPEQVSAAVRAGAAGAISGSAIVKIIEKNLASPKQMLAELRSFVSAMKAASRA", "length": 268, "reference_go_mf": ["GO:0004834"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_c9dfb43fec9bd87b86a5"}, "alternative_alignments": [{"accession": "P0A2K1", "alignment_score": 9.0, "observed_coverage": 0.023076923076923078, "aligned_identity": 0.8333333333333334, "canonical_span": [31, 37], "length": 397, "reference_go_mf": ["GO:0042802", "GO:0004834"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}, {"chain": "B", "status": "assigned", "selected": {"accession": "P0A2K1", "alignment_score": 777.0, "observed_coverage": 1.0, "aligned_identity": 0.9974358974358974, "canonical_span": [1, 391], "sequence": "MTTLLNPYFGEFGGMYVPQILMPALNQLEEAFVSAQKDPEFQAQFADLLKNYAGRPTALTKCQNITAGTRTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKSEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILDKEGRLPDAVIACVGGGSNAIGMFADFINDTSVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTADGQIEESYSISAGLDFPSVGPQHAYLNSIGRADYVSITDDEALEAFKTLCRHEGIIPALESSHALAHALKMMREQPEKEQLLVVNLSGRGDKDIFTVHDILKARGEI", "length": 397, "reference_go_mf": ["GO:0042802", "GO:0004834"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_8ec7a0cdb78481d3d9ee"}, "alternative_alignments": [{"accession": "P00929", "alignment_score": 8.0, "observed_coverage": 0.010256410256410256, "aligned_identity": 1.0, "canonical_span": [232, 236], "length": 268, "reference_go_mf": ["GO:0004834"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_384_1a8h_assembly1", "enzyme_name": "Methionine--tRNA ligase", "ec": ["6.1.1.10"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P23395", "alignment_score": 1000.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 500], "sequence": "MEKVFYVTTPIYYVNAEPHLGHAYTTVVADFLARWHRLDGYRTFFLTGTDEHGETVYRAAQAAGEDPKAFVDRVSGRFKRAWDLLGIAYDDFIRTTEERHKKVVQLVLKKVYEAGDIYYGEYEGLYCVSCERFYTEKELVEGLCPIHGRPVERRKEGNYFFRMEKYRPWLQEYIQENPDLIRPEGYRNEVLAMLAEPIGDLSISRPKSRVPWGIPLPWDENHVTYVWFDALLNYVSALDYPEGEAYRTFWPHAWHLIGKDILKPHAVFWPTMLKAAGIPMYRHLNVGGFLLGPDGRKMSKTLGNVVDPFALLEKYGRDALRYYLLREIPYGQDTPVSEEALRTRYEADLADDLGNLVQRTRAMLFRFAEGRIPEPVAGEELAEGTGLAGRLRPLVRELKFHVALEEAMAYVKALNRYINEKKPWELFKKEPEEARAVLYRVVEGLRIASILLTPAMPDKMAELRRALGLKEEVRLEEAERWGLAEPRPIPEEAPVLFPKKEAKVEAKPKEEAWIGIEDFAKVELRVAEVLAAEKHPNADRLLVLRLSLGNEERTVVSGIAKWYRPEELVGKKVVLVANLKPAKLRGIESQGMILAAQEGEALALVTVEGEVPPGAVVK", "length": 618, "reference_go_mf": ["GO:0005524", "GO:0004825", "GO:0000049"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_2f31bda1152e54c363e5"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_385_1eg7_assembly2", "enzyme_name": "formyltetrahydrofolate synthetase", "ec": ["6.3.4.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P21164", "alignment_score": 1085.5, "observed_coverage": 1.0, "aligned_identity": 0.9963570127504554, "canonical_span": [6, 557], "sequence": "MSKVPSDIEIAQAAKMKPVMELARGLGIQEDEVELYGKYKAKISLDVYRRLKDKPDGKLILVTAITPTPAGEGKTTTSVGLTDALARLGKRVMVCLREPSLGPSFGIKGGAAGGGYAQVVPMEDINLHFTGDIHAVTYAHNLLAAMVDNHLQQGNVLNIDPRTITWRRVIDLNDRALRNIVIGLGGKANGVPRETGFDISVASEVMACLCLASDLMDLKERFSRIVVGYTYDGKPVTAGDLEAQGSMALLMKDAIKPNLVQTLENTPAFIHGGPFANIAHGCNSIIATKTALKLADYVVTEAGFGADLGAEKFYDVKCRYAGFKPDATVIVATVRALKMHGGVPKSDLATENLEALREGFANLEKHIENIGKFGVPAVVAINAFPTDTEAELNLLYELCAKAGAEVALSEVWAKGGEGGLELARKVLQTLESRPSNFHVLYNLDLSIKDKIAKIATEIYGADGVNYTAEADKAIQRYESLGYGNLPVVMAKTQYSFSDDMTKLGRPRNFTITVREVRLSAGGRLIVPITGAIMTMPGLPKRPAACNIDIDADGVITGLF", "length": 559, "reference_go_mf": ["GO:0005524", "GO:0004329"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_c64a1b0cbc2d432d2e51"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_386_1qi9_assembly1", "enzyme_name": "Vanadium-dependent bromoperoxidase (HOBr Formation)", "ec": ["1.11.1.18"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P81701", "alignment_score": 1110.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 556], "sequence": "QTCSTSDDADDPTPPNERDDEAFASRVAAAKRELEGTGTVCQINNGETDLAAKFHKSLPHDDLGQVDADAFAALEDCILNGDLSICEDVPVGNSEGDPVGRLVNPTAAFAIDISGPAFSATTIPPVPTLPSPELAAQLAEVYWMALARDVPFMQYGTDDITVTAAANLAGMEGFPNLDAVSIGSDGTVDPLSQLFRATFVGVETGPFISQLLVNSFTIDSITVEPKQETFAPDVNYMVDFDEWLNIQNGGPPAGPELLDDELRFVRNARDLARVTFTDNINTEAYRGALILLGLDAFNRAGVNGPFIDIDRQAGFVNFGISHYFRLIGAAELAQRSSWYQKWQVHRFARPEALGGTLHLTIKGELNADFDLSLLENAELLKRVAAINAAQNPNNEVTYLLPQAIQEGSPTHPSYPSGHATQNGAFATVLKALIGLDRGGDCYPDPVYPDDDGLKLIDFRGSCLTFEGEINKLAVNVAFGRQMLGIHYRFDGIQGLLLGETITVRTLHQELMTFAEESTFEFRLFTGEVIKLFQDGTFTIDGFKCPGLVYTGVENCVS", "length": 557, "reference_go_mf": ["GO:0019806"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_25a41147978eec7f04ab"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_387_1yph_assembly1", "enzyme_name": "chymotrypsinogen A", "ec": ["3.4.21.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00766", "alignment_score": 262.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [15, 146], "sequence": "CGVPAIQPVLSGLSRIVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHCGVTTSDVVVAGEFDQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSAVCLPSASDDFAAGTTCVTTGWGLTRYTNANTPDRLQQASLPLLSNTNCKKYWGTKIKDAMICAGASGVSSCMGDSGGPLVCKKNGAWTLVGIVSWGSSTCSTSTPGVYARVTALVNWVQQTLAAN", "length": 245, "reference_go_mf": ["GO:0004252", "GO:0097655"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_430105fda0f3959453bc"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P00766", "alignment_score": 194.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [148, 245], "sequence": "CGVPAIQPVLSGLSRIVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHCGVTTSDVVVAGEFDQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSAVCLPSASDDFAAGTTCVTTGWGLTRYTNANTPDRLQQASLPLLSNTNCKKYWGTKIKDAMICAGASGVSSCMGDSGGPLVCKKNGAWTLVGIVSWGSSTCSTSTPGVYARVTALVNWVQQTLAAN", "length": 245, "reference_go_mf": ["GO:0004252", "GO:0097655"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_430105fda0f3959453bc"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_388_5hrc_assembly1", "enzyme_name": "aspartate racemase (CT type)", "ec": ["5.1.1.13"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "A0A0H3JGH6", "alignment_score": 460.0, "observed_coverage": 0.9913793103448276, "aligned_identity": 1.0, "canonical_span": [0, 230], "sequence": "MKTIGLLGGMSWESTIPYYRLINEGIKQRLGGLHSAQVLLHSVDFHEIEECQRRGEWDKTGDILAEAALGLQRAGAEGIVLCTNTMHKVADAIESRCTLPFLHIADATGRAITGAGMTRVALLGTRYTMEQDFYRGRLTEQFSINCLIPEADERAKINQIIFEELCLGQFTEASRAYYAQVIARLAEQGAQGVIFGCTEIGLLVPEERSVLPVFDTAAIHAEDAVAFMLS", "length": 230, "reference_go_mf": ["GO:0047689", "GO:0008881"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_d49c37c665e6ffc55585"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_389_1a4i_assembly1", "enzyme_name": "methylenetetrahydrofolate dehydrogenase (NADP+)", "ec": ["1.5.1.5"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P11586", "alignment_score": 556.5, "observed_coverage": 1.0, "aligned_identity": 0.9964912280701754, "canonical_span": [1, 296], "sequence": "MAPAEILNGKEISAQIRARLKNQVTQLKEQVPGFTPRLAILQVGNRDDSNLYINVKLKAAEEIGIKATHIKLPRTTTESEVMKYITSLNEDSTVHGFLVQLPLDSENSINTEEVINAIAPEKDVDGLTSINAGKLARGDLNDCFIPCTPKGCLELIKETGVPIAGRHAVVVGRSKIVGAPMHDLLLWNNATVTTCHSKTAHLDEEVNKGDILVVATGQPEMVKGEWIKPGAIVIDCGINYVPDDKKPNGRKVVGDVAYDEAKERASFITPVPGGVGPMTVAMLMQSTVESAKRFLEKFKPGKWMIQYNNLNLKTPVPSDIDISRSCKPKPIGKLAREIGLLSEEVELYGETKAKVLLSALERLKHRPDGKYVVVTGITPTPLGEGKSTTTIGLVQALGAHLYQNVFACVRQPSQGPTFGIKGGAAGGGYSQVIPMEEFNLHLTGDIHAITAANNLVAAAIDARIFHELTQTDKALFNRLVPSVNGVRRFSDIQIRRLKRLGIEKTDPTTLTDEEINRFARLDIDPETITWQRVLDTNDRFLRKITIGQAPTEKGHTRTAQFDISVASEIMAVLALTTSLEDMRERLGKMVVASSKKGEPVSAEDLGVSGALTVLMKDAIKPNLMQTLEGTPVFVHAGPFANIAHGNSSIIADRIALKLVGPEGFVVTEAGFGADIGMEKFFNIKCRYSGLCPHVVVLVATVRALKMHGGGPTVTAGLPLPKAYIQENLELVEKGFSNLKKQIENARMFGIPVVVAVNAFKTDTESELDLISRLSREHGAFDAVKCTHWAEGGKGALALAQAVQRAAQAPSSFQLLYDLKLPVEDKIRIIAQKIYGADDIELLPEAQHKAEVYTKQGFGNLPICMAKTHLSLSHNPEQKGVPTGFILPIRDIRASVGAGFLYPLVGTMSTMPGLPTRPCFYDIDLDPETEQVNGLF", "length": 935, "reference_go_mf": ["GO:0005524", "GO:0004329", "GO:0004477", "GO:0004488"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_748e6e336c8e454791e2"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_38_1fbx_assembly1", "enzyme_name": "GTP cyclohydrolase I", "ec": ["3.5.4.16"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0A6T5", "alignment_score": 442.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 222], "sequence": "MPSLSKEAALVHEALVARGLETPLRPPVHEMDNETRKSLIAGHMTEIMQLLNLDLADDSLMETPHRIAKMYVDEIFSGLDYANFPKITLIENKMKVDEMVTVRDITLTSTCEHHFVTIDGKATVAYIPKDSVIGLSKINRIVQFFAQRPQVQERLTQQILIALQTLLGTNNVAVSIDAVHYCVKARGIRDATSATTTTSLGGLFKSSQNTRHEFLRAVRHHN", "length": 222, "reference_go_mf": ["GO:0005525", "GO:0003934", "GO:0042802", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_1d7c01a67f6241f34856"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_390_2qt6_assembly1", "enzyme_name": "laccase", "ec": ["1.10.3.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q5EBY5", "alignment_score": 917.0, "observed_coverage": 0.929718875502008, "aligned_identity": 0.9935205183585313, "canonical_span": [0, 463], "sequence": "AVGPVADLTVTNANISPDGFERAAIVVNNVFPAPLITGNMGDNFQLNLVNQMTNHTMLKTTSIHWHGFFQKGTNWADGPAFINQCPIASGNSFLYDFQVPGQAGTFWYHSHLSTQYCDGLRGPFVVYDPNDPHANLYDVDDESTVITLADWYHVAAKLGPRFPLGADSTLINGLGRSTSTPTADLAVISVTKGKRYRFRLVSLSCDPNYTFSIDSHQLTVIEADGVSTQPVTVDSIQIFAAQRYSFVLNANQDVDNYWIRANPNFGTTGFADGVNSAILRYDDADPVEPVTNQTGTTLLLETDLHPLTSMPVPGNPTQGGADLNLNMAFNFDGTNFFINGESFTPPTVPVLLQIISGANTAQDLLPSGSVYSLPSNSSIEITFPATTAAPGAPHPFHLHGHVFAVVRSAGSTSYNYDDPVWRDVVSTGTPQAGDNVTIRFQTDNPGPWFLHCHIDFHLEAGFA", "length": 463, "reference_go_mf": ["GO:0005507", "GO:0052716"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_d6db827418b1e18dbbfc"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_391_1a95_assembly1", "enzyme_name": "xanthine phosphoribosyltransferase", "ec": ["2.4.2.22"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0A9M5", "alignment_score": 283.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [2, 150], "sequence": "MSEKYIVTWDMLQIHARKLASRLMPSEQWKGIIAVSRGGLVPGALLARELGIRHVDTVCISSYDHDNQRELKVLKRAEGDGEGFIVIDDLVDTGGTAVAIREMYPKAHFVTIFAKPAGRPLVDDYVVDIPQDTWIEQPWDMGVVFVPPISGR", "length": 152, "reference_go_mf": ["GO:0052657", "GO:0097216", "GO:0004422", "GO:0042802", "GO:0000287", "GO:0000310"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_2c221cf1a5ddadac6f8f"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_393_1agm_assembly1", "enzyme_name": "glucan 1,4-alpha-glucosidase", "ec": ["3.2.1.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P69327", "alignment_score": 868.0, "observed_coverage": 1.0, "aligned_identity": 0.9531914893617022, "canonical_span": [24, 495], "sequence": "MSFRSLLALSGLVCTGLANVISKRATLDSWLSNEATVARTAILNNIGADGAWVSGADSGIVVASPSTDNPDYFYTWTRDSGLVLKTLVDLFRNGDTSLLSTIENYISAQAIVQGISNPSGDLSSGAGLGEPKFNVDETAYTGSWGRPQRDGPALRATAMIGFGQWLLDNGYTSTATDIVWPLVRNDLSYVAQYWNQTGYDLWEEVNGSSFFTIAVQHRALVEGSAFATAVGSSCSWCDSQAPEILCYLQSFWTGSFILANFDSSRSGKDANTLLGSIHTFDPEAACDDSTFQPCSPRALANHKEVVDSFRSIYTLNDGLSDSEAVAVGRYPEDTYYNGNPWFLCTLAAAEQLYDALYQWDKQGSLEVTDVSLDFFKALYSDAATGTYSSSSSTYSSIVDAVKTFADGFVSIVETHAASNGSMSEQYDKSDGEQLSARDLTWSYAALLTANNRRNSVVPASWGETSASSVPGTCAATSAIGTYSSVTVTSWPSIVATGGTTTTATPTGSGSVTSTSKTTATASKTSTSTSSTSCTTPTAVAVTFDLTATTTYGENIYLVGSISQLGDWETSDGIALSADKYTSSDPLWYVTVTLPAGESFEYKFIRIESDDSVEWESDPNREYTVPQACGTSTATVTDTWR", "length": 640, "reference_go_mf": ["GO:0004339", "GO:2001070"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_fdd2d83df521a8efce64"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_395_1ak0_assembly1", "enzyme_name": "nuclease P1", "ec": ["3.1.30.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P24289", "alignment_score": 528.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 264], "sequence": "WGALGHATVAYVAQHYVSPEAASWAQGILGSSSSSYLASIASWADEYRLTSAGKWSASLHFIDAEDNPPTNCNVDYERDCGSSGCSISAIANYTQRVSDSSLSSENHAEALRFLVHFIGDMTQPLHDEAYAVGGNKINVTFDGYHDNLHSDWDTYMPQKLIGGHALSDAESWAKTLVQNIESGNYTAQAIGWIKGDNISEPITTATRWASDANALVCTVVMPHGAAALQTGDLYPTYYDSVIDTIELQIAKGGYRLANWINEIHGSEIAK", "length": 270, "reference_go_mf": ["GO:0004519", "GO:0016788", "GO:0003676"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_d75cf836386fdbcc0d05"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_396_1am5_assembly1", "enzyme_name": "aspartic peptidase", "ec": ["3.4.23.-"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P56272", "alignment_score": 648.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 324], "sequence": "RVTEQMKNEADTEYYGVISIGTPPESFKVIFDTGSSNLWVSSSHCSAQACSNHNKFKPRQSSTYVETGKTVDLTYGTGGMRGILGQDTVSVGGGSDPNQELGESQTEPGPFQAAAPFDGILGLAYPSIAAAGAVPVFDNMGSQSLVEKDLFSFYLSGGGANGSEVMLGGVDNSHYTGSIHWIPVTAEKYWQVALDGITVNGQTAACEGCQAIVDTGTSKIVAPVSALANIMKDIGASENQGEMMGNCASVQSLPDITFTINGVKQPLPPSAYIEGDQAFCTSGLGSSGVPSNTSELWIFGDVFLRNYYTIYDRTNNKVGFAPAA", "length": 324, "reference_go_mf": ["GO:0004190"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_715d698004a55c24197b"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_397_1amy_assembly1", "enzyme_name": "alpha-amylase", "ec": ["3.2.1.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P04063", "alignment_score": 806.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [24, 427], "sequence": "MANKHLSLSLFLVLLGLSASLASGQVLFQGFNWESWKHNGGWYNFLMGKVDDIAAAGITHVWLPPASQSVAEQGYMPGRLYDLDASKYGNKAQLKSLIGALHGKGVKAIADIVINHRTAEHKDGRGIYCIFEGGTPDARLDWGPHMICRDDRPYADGTGNPDTGADFGAAPDIDHLNLRVQKELVEWLNWLKADIGFDGWRFDFAKGYSADVAKIYIDRSEPSFAVAEIWTSLAYGGDGKPNLNQDQHRQELVNWVDKVGGKGPATTFDFTTKGILNVAVEGELWRLRGTDGKAPGMIGWWPAKAVTFVDNHDTGSTQHMWPFPSDRVMQGYAYILTHPGTPCIFYDHFFDWGLKEEIDRLVSVRTRHGIHNESKLQIIEADADLYLAEIDGKVIVKLGPRYDVGNLIPGGFKVAAHGNDYAVWEKI", "length": 427, "reference_go_mf": ["GO:0004556", "GO:0005509"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_16aaae0b87e0825ba7f3"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_398_1aop_assembly1", "enzyme_name": "sulfite reductase (NADPH)", "ec": ["1.8.1.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P17846", "alignment_score": 878.5, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [80, 570], "sequence": "MSEKHPGPLVVEGKLTDAERMKHESNYLRGTIAEDLNDGLTGGFKGDNFLLIRFHGMYQQDDRDIRAERAEQKLEPRHAMLLRCRLPGGVITTKQWQAIDKFAGENTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSNPYESQLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVATTDEEPILGQTYLPRKFKTTVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGVETFKAEVERRAGIKFEPIRPYEFTGRGDRIGWVKGIDDNWHLTLFIENGRILDYPARPLKTGLLEIAKIHKGDFRITANQNLIIAGVPESEKAKIEKIAKESGLMNAVTPQRENSMACVSFPTCPLAMAEAERFLPSFIDNIDNLMAKHGVSDEHIVMRVTGCPNGCGRAMLAEVGLVGKAPGRYNLHLGGNRIGTRIPRMYKENITEPEILASLDELIGRWAKEREAGEGFGDFTVRAGIIRPVLDPARDLWD", "length": 570, "reference_go_mf": ["GO:0051539", "GO:0020037", "GO:0050661", "GO:0004783"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_9666bc0743e9bcd4d3af"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_399_1apx_assembly1", "enzyme_name": "L-ascorbate peroxidase", "ec": ["1.11.1.11"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P48534", "alignment_score": 498.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 250], "sequence": "MGKSYPTVSPDYQKAIEKAKRKLRGFIAEKKCAPLILRLAWHSAGTFDSKTKTGGPFGTIKHQAELAHGANNGLDIAVRLLEPIKEQFPIVSYADFYQLAGVVAVEITGGPEVPFHPGREDKPEPPPEGRLPDATKGSDHLRDVFGKAMGLSDQDIVALSGGHTIGAAHKERSGFEGPWTSNPLIFDNSYFTELLTGEKDGLLQLPSDKALLTDSVFRPLVEKYAADEDVFFADYAEAHLKLSELGFAEA", "length": 250, "reference_go_mf": ["GO:0020037", "GO:0016688"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_b5b1929d69fe080d3a9a"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_39_2mas_assembly1", "enzyme_name": "inosine-uridine preferring nucleoside hydrolase", "ec": ["3.2.2.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q27546", "alignment_score": 624.0, "observed_coverage": 0.9968051118210862, "aligned_identity": 1.0, "canonical_span": [2, 314], "sequence": "MPKKIILDCDPGLDDAVAILLAHGNPEIELLAITTVVGNQTLAKVTRNAQLVADIAGITGVPIAAGCDKPLVRKIMTAGHIHGESGMGTVAYPAEFKNKVDERHAVNLIIDLVMSHEPKTITLVPTGGLTNIAMAARLEPRIVDRVKEVVLMGGGYHEGNATSVAEFNIIIDPEAAHIVFNESWQVTMVGLDLTHQALATPPILQRVKEVDTNPARFMLEIMDYYTKIYQSNRYMAAAAVHDPCAVAYVIDPSVMTTERVPVDIELTGKLTLGMTVADFRNPRPEHCHTQVAVKLDFEKFWGLVLDALERIGDPQ", "length": 315, "reference_go_mf": ["GO:0047724", "GO:0045437"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_8e890c2fcb2db6c7ea1d"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_3_1d4a_assembly1", "enzyme_name": "NAD(P)H dehydrogenase (quinone)", "ec": ["1.6.5.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P15559", "alignment_score": 546.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 274], "sequence": "MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKLKDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQFPLQWFGVPAILKGWFERVFIGEFAYTYAAMYDKGPFRSKKAVLSITTGGSGSMYSLQGIHGDMNVILWPIQSGILHFCGFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMKKEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK", "length": 274, "reference_go_mf": ["GO:0004128", "GO:0042802", "GO:0003955", "GO:0050136", "GO:0008753", "GO:0003723"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_f7316e90f68b60994d35"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_400_1aq0_assembly1", "enzyme_name": "licheninase (glycosyl hydrolase 17 family)", "ec": ["3.2.1.73"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P12257", "alignment_score": 609.0, "observed_coverage": 1.0, "aligned_identity": 0.9967320261437909, "canonical_span": [6, 312], "sequence": "PPSVESIGVCYGMSANNLPAASTVVSMFKFNGIKSMRLYAPNQAALQAVGGTGINVVVGAPNDVLSNLAASPAAAASWVKSNIQAYPKVSFRYVCVGNEVAGGATRNLVPAMKNVHGALVAAGLGHIKVTTSVSQAILGVFSPPSAGSFTGEAAAFMGPVVQFLARTNAPLMANIYPYLAWAYNPSAMDMGYALFNASGTVVRDGAYGYQNLFDTTVDAFYTAMGKHGGSSVKLVVSESGWPSGGGTAATPANARFYNQHLINHVGRGTPRHPGAIETYIFAMFNENQKDSGVEQNWGLFYPNMQHVYPINF", "length": 312, "reference_go_mf": ["GO:0042973", "GO:0042972"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_54194d67153f502eecd2"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_401_1aql_assembly1", "enzyme_name": "bile salt-activated lipase", "ec": ["3.1.1.13"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P30122", "alignment_score": 1064.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [18, 550], "sequence": "LGASRLGPSPGCLAVASAAKLGSVYTEGGFVEGVNKKLSLFGDSIDIFKGIPFAAAPKALEKPERHPGWQGTLKAKSFKKRCLQATLTQDSTYGNEDCLYLNIWVPQGRKEVSHDLPVMIWIYGGAFLMGASQGANFLSNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDSNLPGNYGLWDQHMAIAWVKRNIEAFGGDPDNITLFGESAGGASVSLQTLSPYNKGLIKRAISQSGVGLCPWAIQQDPLFWAKRIAEKVGCPVDDTSKMAGCLKITDPRALTLAYKLPLGSTEYPKLHYLSFVPVIDGDFIPDDPVNLYANAADVDYIAGTNDMDGHLFVGMDVPAINSNKQDVTEEDFYKLVSGLTVTKGLRGANATYEVYTEPWAQDSSQETRKKTMVDLETDILFLIPTKIAVAQHKSHAKSANTYTYLFSQPSRMPIYPKWMGADHADDLQYVFGKPFATPLGYRAQDRTVSKAMIAYWTNFARTGDPNTGHSTVPANWDPYTLEDDNYLEINKQMDSNSMKLHLRTNYLQFWTQTYQALPTVTSAGASLLPPEDNSQASPVPPADNSGAPTEPSAGDSEVAQMPVVIGF", "length": 597, "reference_go_mf": ["GO:0008126", "GO:0120573", "GO:0050253", "GO:0004771", "GO:0004806"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_9b10580e1e6ba2846fc0"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_403_1ast_assembly1", "enzyme_name": "astacin", "ec": ["3.4.24.21"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P07584", "alignment_score": 400.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [49, 249], "sequence": "MQCAVLLVLLGVVAASPIIPEAARALYYNDGMFEGDIKLRAGRQPARVGAAILGDEYLWSGGVIPYTFAGVSGADQSAILSGMQELEEKTCIRFVPRTTESDYVEIFTSGSGCWSYVGRISGAQQVSLQANGCVYHGTIIHELMHAIGFYHEHTRMDRDNYVTINYQNVDPSMTSNFDIDTYSRYVGEDYQYYSIMHYGKYSFSIQWGVLETIVPLQNGIDLTDPYDKAHMLQTDANQINNLYTNECSLRH", "length": 251, "reference_go_mf": ["GO:0070001", "GO:0070002", "GO:0004222", "GO:0008233", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_d4ec962a8446294eb341"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_404_1asy_assembly1", "enzyme_name": "aspartate---tRNA ligase", "ec": ["6.1.1.12"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P04802", "alignment_score": 980.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [67, 557], "sequence": "MSQDENIVKAVEESAEPAQVILGEDGKPLSKKALKKLQKEQEKQRKKEERALQLEAEREAREKKAAAEDTAKDNYGKLPLIQSRDSDRTGQKRVKFVDLDEAKDSDKEVLFRARVHNTRQQGATLAFLTLRQQASLIQGLVKANKEGTISKNMVKWAGSLNLESIVLVRGIVKKVDEPIKSATVQNLEIHITKIYTISETPEALPILLEDASRSEAEAEAAGLPVVNLDTRLDYRVIDLRTVTNQAIFRIQAGVCELFREYLATKKFTEVHTPKLLGAPSEGGSSVFEVTYFKGKAYLAQSPQFNKQQLIVADFERVYEIGPVFRAENSNTHRHMTEFTGLDMEMAFEEHYHEVLDTLSELFVFIFSELPKRFAHEIELVRKQYPVEEFKLPKDGKMVRLTYKEGIEMLRAAGKEIGDFEDLSTENEKFLGKLVRDKYDTDFYILDKFPLEIRPFYTMPDPANPKYSNSYDFFMRGEEILSGAQRIHDHALLQERMKAHGLSPEDPGLKDYCDGFSYGCPPHAGGGIGLERVVMFYLDLKNIRRASLFPRDPKRLRP", "length": 557, "reference_go_mf": ["GO:0004815", "GO:0005524", "GO:0003723", "GO:1990825"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_bca8a0456085e476c0bb"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_405_1at1_assembly1", "enzyme_name": "aspartate carbamoyltransferase", "ec": ["2.1.3.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0A786", "alignment_score": 608.0, "observed_coverage": 1.0, "aligned_identity": 0.9870967741935484, "canonical_span": [1, 311], "sequence": "MANPLYQKHIISINDLSRDDLNLVLATAAKLKANPQPELLKHKVIASCFFEASTRTRLSFETSMHRLGASVVGFSDSANTSLGKKGETLADTISVISTYVDAIVMRHPQEGAARLATEFSGNVPVLNAGDGSNQHPTQTLLDLFTIQETQGRLDNLHVAMVGDLKYGRTVHSLTQALAKFDGNRFYFIAPDALAMPQYILDMLDEKGIAWSLHSSIEEVMAEVDILYMTRVQKERLDPSEYANVKAQFVLRASDLHNAKANMKVLHPLPRVDEIATDVDKTPHAWYFQQAGNGIFARQALLALVLNRDLVL", "length": 311, "reference_go_mf": ["GO:0016597", "GO:0004070", "GO:0042802"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_de56864d83a9563b2727"}, "alternative_alignments": [{"accession": "P0A7F3", "alignment_score": 9.0, "observed_coverage": 0.01935483870967742, "aligned_identity": 0.8333333333333334, "canonical_span": [143, 149], "length": 153, "reference_go_mf": ["GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}, {"chain": "B", "status": "assigned", "selected": {"accession": "P0A786", "alignment_score": 608.0, "observed_coverage": 1.0, "aligned_identity": 0.9870967741935484, "canonical_span": [1, 311], "sequence": "MANPLYQKHIISINDLSRDDLNLVLATAAKLKANPQPELLKHKVIASCFFEASTRTRLSFETSMHRLGASVVGFSDSANTSLGKKGETLADTISVISTYVDAIVMRHPQEGAARLATEFSGNVPVLNAGDGSNQHPTQTLLDLFTIQETQGRLDNLHVAMVGDLKYGRTVHSLTQALAKFDGNRFYFIAPDALAMPQYILDMLDEKGIAWSLHSSIEEVMAEVDILYMTRVQKERLDPSEYANVKAQFVLRASDLHNAKANMKVLHPLPRVDEIATDVDKTPHAWYFQQAGNGIFARQALLALVLNRDLVL", "length": 311, "reference_go_mf": ["GO:0016597", "GO:0004070", "GO:0042802"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_de56864d83a9563b2727"}, "alternative_alignments": [{"accession": "P0A7F3", "alignment_score": 9.0, "observed_coverage": 0.01935483870967742, "aligned_identity": 0.8333333333333334, "canonical_span": [143, 149], "length": 153, "reference_go_mf": ["GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_406_1aui_assembly1", "enzyme_name": "protein phosphatase 2B", "ec": ["3.1.3.16"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q08209", "alignment_score": 720.0, "observed_coverage": 0.9523809523809523, "aligned_identity": 1.0, "canonical_span": [13, 373], "sequence": "MSEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESVALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESVLTLKGLTPTGMLPSGVLSGGKQTLQSATVEAIEADEAIKGFSPQHKITSFEEAKGLDRINERMPPRRDAMPSDANLNSINKALTSETNGTDSNGSNSSNIQ", "length": 521, "reference_go_mf": ["GO:0051117", "GO:0005509", "GO:0005516", "GO:0033192", "GO:0019899", "GO:0046983", "GO:0004722"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_f6aaf7e71a1fc0001082"}, "alternative_alignments": [{"accession": "P63098", "alignment_score": 8.0, "observed_coverage": 0.026455026455026454, "aligned_identity": 0.6, "canonical_span": [61, 71], "length": 170, "reference_go_mf": ["GO:0005509", "GO:0004723", "GO:0008597", "GO:0005516", "GO:0019902", "GO:0019904"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_407_2o7r_assembly1", "enzyme_name": "carboxylesterase", "ec": ["3.1.1.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q0ZPV7", "alignment_score": 606.5, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [17, 328], "sequence": "MSNDHLETTGSSDPNTNLLKYLPIVLNPDRTITRPIQIPSTAASPDPTSSSPVLTKDLALNPLHNTFVRLFLPRHALYNSAKLPLVVYFHGGGFILFSAASTIFHDFCCEMAVHAGVVIASVDYRLAPEHRLPAAYDDAMEALQWIKDSRDEWLTNFADFSNCFIMGESAGGNIAYHAGLRAAAVADELLPLKIKGLVLDEPGFGGSKRTGSELRLANDSRLPTFVLDLIWELSLPMGADRDHEYCNPTAESEPLYSFDKIRSLGWRVMVVGCHGDPMIDRQMELAERLEKKGVDVVAQFDVGGYHAVKLEDPEKAKQFFVILKKFVVDSCTTKL", "length": 335, "reference_go_mf": ["GO:0106435"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_5beb138e63fce2ae129a"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_408_1auw_assembly1", "enzyme_name": "argininosuccinate lyase", "ec": ["4.3.2.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P24058", "alignment_score": 885.0, "observed_coverage": 1.0, "aligned_identity": 0.9932885906040269, "canonical_span": [18, 465], "sequence": "MASEARGDKLWGGRFSGSTDPIMEKLNSSIAYDQRLSEVDIQGSMAYAKALEKAGILTKTELEKILSGLEKISEEWSKGVFVVKQSDEDIHTANERRLKELIGDIAGKLHTGRSRNDQVVTDLKLFMKNSLSIISTHLLQLIKTLVERAAIEIDVILPGYTHLQKAQPIRWSQFLLSHAVALTRDSERLGEVKKRINVLPLGSGALAGNPLDIDREMLRSELEFASISLNSMDAISERDFVVEFLSFATLLMIHLSKMAEDLIIYSTSEFGFLTLSDAFSTGSSLMPQKKNPDSLELIRSKAGRVFGRLASILMVLKGLPSTYNKDLQEDKEAVFDVVDTLTAVLQVATGVISTLQISKENMEKALTPEMLATDLALYLVRKGVPFRQAHTASGKAVHLAETKGITINKLSLEDLKSISPQFSSDVSQVFNFVNSVEQYTALAGTAKSSVTTQIEQLRELMKKQKEQA", "length": 468, "reference_go_mf": ["GO:0004056", "GO:0005212"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_454b0fb8de143bcd8dbd"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P24058", "alignment_score": 885.0, "observed_coverage": 1.0, "aligned_identity": 0.9932885906040269, "canonical_span": [18, 465], "sequence": "MASEARGDKLWGGRFSGSTDPIMEKLNSSIAYDQRLSEVDIQGSMAYAKALEKAGILTKTELEKILSGLEKISEEWSKGVFVVKQSDEDIHTANERRLKELIGDIAGKLHTGRSRNDQVVTDLKLFMKNSLSIISTHLLQLIKTLVERAAIEIDVILPGYTHLQKAQPIRWSQFLLSHAVALTRDSERLGEVKKRINVLPLGSGALAGNPLDIDREMLRSELEFASISLNSMDAISERDFVVEFLSFATLLMIHLSKMAEDLIIYSTSEFGFLTLSDAFSTGSSLMPQKKNPDSLELIRSKAGRVFGRLASILMVLKGLPSTYNKDLQEDKEAVFDVVDTLTAVLQVATGVISTLQISKENMEKALTPEMLATDLALYLVRKGVPFRQAHTASGKAVHLAETKGITINKLSLEDLKSISPQFSSDVSQVFNFVNSVEQYTALAGTAKSSVTTQIEQLRELMKKQKEQA", "length": 468, "reference_go_mf": ["GO:0004056", "GO:0005212"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_454b0fb8de143bcd8dbd"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_40_13pk_assembly1", "enzyme_name": "phosphoglycerate kinase", "ec": ["2.7.2.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P07378", "alignment_score": 824.0, "observed_coverage": 1.0, "aligned_identity": 0.9951807228915662, "canonical_span": [4, 419], "sequence": "MTLNEKKSINECDLKGKKVLIRVDFNVPVKNGKITNDYRIRSALPTLKKVLTEGGSCVLMSHLGRPKGIPMAQAGKIRSTGGVPGFQQKATLKPVAKALSELLLRPVTFAPDCLNAADVVSKMSPGDVVLLENVRFYKEEGSKKAKDREAMAKILASYGDVYISDAFGTAHRDSATMTGIPKILGNGAAGYLMEKEISYFAKVLGNPPRPLVAIVGGAKVSDKIQLLDNMLQRIDYLLIGGAMAYTFLKAQGYSIGKSKCEESKLEFARSLLKKAEDRKVQVILPIDHVCHTEFKAVDSPLITEDQNIPEGHMALDIGPKTIEKYVQTIGKCKSAIWNGPMGVFEMVPYSKGTFAIAKAMGRGTHEHGLMSIIGGGDSASAAELSGEAKRMSHVSTGGGASLELLEGKTLPGVTVLDEKSAVVSYASAGTGTLSNRWSSL", "length": 440, "reference_go_mf": ["GO:0043531", "GO:0005524", "GO:0004618"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_54f8440e1576e6f4bdc3"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_411_1ay4_assembly1", "enzyme_name": "aromatic-amino-acid transaminase", "ec": ["2.6.1.57"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P95468", "alignment_score": 788.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 394], "sequence": "MLGNLKPQAPDKILALMGEFRADPRQGKIDLGVGVYKDATGHTPIMRAVHAAEQRMLETETTKTYAGLSGEPEFQKAMGELILGDGLKSETTATLATVGGTGALRQALELARMANPDLRVFVSDPTWPNHVSIMNFMGLPVQTYRYFDAETRGVDFEGMKADLAAAKKGDMVLLHGCCHNPTGANLTLDQWAEIASILEKTGALPLIDLAYQGFGDGLEEDAAGTRLIASRIPEVLIAASCSKNFGIYRERTGCLLALCADAATRELAQGAMAFLNRQTYSFPPFHGAKIVSTVLTTPELRADWMAELEAVRSGMLRLREQLAGELRDLSGSDRFGFVAEHRGMFSRLGATPEQVKRIKEEFGIYMVGDSRINIAGLNDNTIPILARAIIEVGV", "length": 394, "reference_go_mf": ["GO:0042802", "GO:0004069", "GO:0004838", "GO:0030170"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_6e8b1294b75deffef702"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_412_1azw_assembly1", "enzyme_name": "prolyl aminopeptidase", "ec": ["3.4.11.5"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P52279", "alignment_score": 599.0, "observed_coverage": 1.0, "aligned_identity": 0.9712460063897763, "canonical_span": [0, 313], "sequence": "MRTLYPEITPYQQGSLKVDDRHTLYFEQCGNPHGKPVVMLHGGPGGGCNDKMRRFHDPAKYRIVLFDQRGSGRSTPHADLVDNTTWDLVADIERLRTHLGVDRWQVFGGSWGSTLALAYAADPSAAGHQLVLRGIFLLRRFELEWFYQEGASRLFPDAWEHYLNAIPPVERADLMSAFHRRLTSDDEATRLAAAKAWSVWEGATSFLHVDEDFVTGHEDAHFALAFARIENHYFVNGGFFEVEDQLLRDAHRIADIPGVIVHGRYDVVCPLQSAWDLHKAWPKAQLQISPASGHSAFEPENVDALVRATDGFA", "length": 313, "reference_go_mf": ["GO:0004177"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_5d4756ca6d6f5e1f9db5"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_413_1azy_assembly1", "enzyme_name": "thymidine phosphorylase", "ec": ["2.4.2.4"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P07650", "alignment_score": 878.0, "observed_coverage": 0.9977272727272727, "aligned_identity": 1.0, "canonical_span": [1, 440], "sequence": "MFLAQEIIRKKRDGHALSDEEIRFFINGIRDNTISEGQIAALAMTIFFHDMTMPERVSLTMAMRDSGTVLDWKSLHLNGPIVDKHSTGGVGDVTSLMLGPMVAACGGYIPMISGRGLGHTGGTLDKLESIPGFDIFPDDNRFREIIKDVGVAIIGQTSSLAPADKRFYATRDITATVDSIPLITASILAKKLAEGLDALVMDVKVGSGAFMPTYELSEALAEAIVGVANGAGVRTTALLTDMNQVLASSAGNAVEVREAVQFLTGEYRNPRLFDVTMALCVEMLISGKLAKDDAEARAKLQAVLDNGKAAEVFGRMVAAQKGPTDFVENYAKYLPTAMLTKAVYADTEGFVSEMDTRALGMAVVAMGGGRRQASDTIDYSVGFTDMARLGDQVDGQRPLAVIHAKDENNWQEAAKAVKAAIKLADKAPESTPTVYRRISE", "length": 440, "reference_go_mf": ["GO:0004645", "GO:0009032"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_3be5357697ef18007ae0"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_414_1b2m_assembly1", "enzyme_name": "ribonuclease T1", "ec": ["3.1.27.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00651", "alignment_score": 208.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [26, 130], "sequence": "MMYSKLLTLTTLLLPTALALPSLVERACDYTCGSNCYSSSDVSTAQAAGYQLHEDGETVGSNSYPHKYNNYEGFDFSVSSPYYEWPILSSGDVYSGGSPGADRVVFNENNQLAGVITHTGASGNNFVECT", "length": 130, "reference_go_mf": ["GO:0046589", "GO:0003723"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_0a1b314cab08954e4172"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_415_1b6g_assembly1", "enzyme_name": "haloalkane dehalogenase (subfamily 1)", "ec": ["3.8.1.5"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P22643", "alignment_score": 601.0, "observed_coverage": 1.0, "aligned_identity": 0.9967532467532467, "canonical_span": [0, 310], "sequence": "MINAIRTPDQRFSNLDQYPFSPNYLDDLPGYPGLRAHYLDEGNSDAEDVFLCLHGEPTWSYLYRKMIPVFAESGARVIAPDFFGFGKSDKPVDEEDYTFEFHRNFLLALIERLDLRNITLVVQDWGGFLGLTLPMADPSRFKRLIIMNACLMTDPVTQPAFSAFVTQPADGFTAWKYDLVTPSDLRLDQFMKRWAPTLTEAEASAYAAPFPDTSYQAGVRKFPKMVAQRDQACIDISTEAISFWQNDWNGQTFMAIGMKDKLLGPDVMYPMKALINGCPEPLEIADAGHFVQEFGEQVAREALKHFAETE", "length": 310, "reference_go_mf": ["GO:0004301", "GO:0018786"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_7c3388a577fe60ea11c4"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_416_1h7a_assembly1", "enzyme_name": "ribonucleoside-triphosphate reductase (class III)", "ec": ["1.17.4.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P07071", "alignment_score": 1123.0, "observed_coverage": 1.0, "aligned_identity": 0.9982238010657194, "canonical_span": [26, 589], "sequence": "MTIEKEIEGLIHKTNKDLLNENANKDSRVFPTQRDLMAGIVSKHIAKNMVPSFIMKAHESGIIHVHDIDYSPALPFTNCCLVDLKGMLENGFKLGNAQIETPKSIGVATAIMAQITAQVASHQYGGTTFANVDKVLSPYVKRTYAKHIEDAEKWQIADALNYAQSKTEKDVYDAFQAYEYEVNTLFSSNGQTPFVTITFGTGTDWTERMIQKAILKNRIKGLGRDGITPIFPKLVMFVEEGVNLYKDDPNYDIKQLALECASKRMYPDIISAKNNKAITGSSVPVSPMGCRSFLSVWKDSTGNEILDGRNNLGVVTLNLPRIALDSYIGTQFNEQKFVELFNERMDLCFEALMCRISSLKGVKATVAPILYQEGAFGVRLKPDDDIIELFKNGRSSVSLGYIGIHELNILVGRDIGREILTKMNAHLKQWTERTGFAFSLYSTPAENLCYRFCKLDTEKYGSVKDVTDKGWYTNSFHVSVEENITPFEKISREAPYHFIATGGHISYVELPDMKNNLKGLEAVWDYAAQHLDYFGVNMPVDKCFTCGSTHEMTPTENGFVCSICGETDPKKMNTIRRTCGYLGNPNERGFNLGKNKEIMHRVKHQ", "length": 605, "reference_go_mf": ["GO:0046872", "GO:0008998"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_57706fb7f17eff50cbeb"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_417_1b8f_assembly1", "enzyme_name": "histidine ammonia-lyase", "ec": ["4.3.1.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P21310", "alignment_score": 1002.0, "observed_coverage": 1.0, "aligned_identity": 0.9980237154150198, "canonical_span": [1, 510], "sequence": "MTELTLKPGTLTLAQLRAIHAAPVRLQLDASAAPAIDASVACVEQIIAEDRTAYGINTGFGLLASTRIASHDLENLQRSLVLSHAAGIGAPLDDDLVRLIMVLKINSLSRGFSGIRRKVIDALIALVNAEVYPHIPLKGSVGASGDLAPLAHMSLVLLGEGKARYKGQWLSATEALAVAGLEPLTLAAKEGLALLNGTQASTAYALRGLFYAEDLYAAAIACGGLSVEAVLGSRSPFDARIHEARGQRGQIDTAACFRDLLGDSSEVSLSHKNCDKVQDPYSLRCQPQVMGACLTQLRQAAEVLGIEANAVSDNPLVFAAEGDVISGGNFHAEPVAMAADNLALAIAEIGSLSERRISLMMDKHMSQLPPFLVENGGVNSGFMIAQVTAAALASENKALSHPHSVDSLPTSANQEDHVSMAPAAGKRLWEMAENTRGVLAIEWLGACQGLDLRKGLKTSAKLEKARQALRSEVAHYDRDRFFAPDIEKAVELLAKGSLTGLLPAGVLPSL", "length": 510, "reference_go_mf": ["GO:0004397"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_726876c31beaa93d9ad1"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P21310", "alignment_score": 1002.0, "observed_coverage": 1.0, "aligned_identity": 0.9980237154150198, "canonical_span": [1, 510], "sequence": "MTELTLKPGTLTLAQLRAIHAAPVRLQLDASAAPAIDASVACVEQIIAEDRTAYGINTGFGLLASTRIASHDLENLQRSLVLSHAAGIGAPLDDDLVRLIMVLKINSLSRGFSGIRRKVIDALIALVNAEVYPHIPLKGSVGASGDLAPLAHMSLVLLGEGKARYKGQWLSATEALAVAGLEPLTLAAKEGLALLNGTQASTAYALRGLFYAEDLYAAAIACGGLSVEAVLGSRSPFDARIHEARGQRGQIDTAACFRDLLGDSSEVSLSHKNCDKVQDPYSLRCQPQVMGACLTQLRQAAEVLGIEANAVSDNPLVFAAEGDVISGGNFHAEPVAMAADNLALAIAEIGSLSERRISLMMDKHMSQLPPFLVENGGVNSGFMIAQVTAAALASENKALSHPHSVDSLPTSANQEDHVSMAPAAGKRLWEMAENTRGVLAIEWLGACQGLDLRKGLKTSAKLEKARQALRSEVAHYDRDRFFAPDIEKAVELLAKGSLTGLLPAGVLPSL", "length": 510, "reference_go_mf": ["GO:0004397"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_726876c31beaa93d9ad1"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_418_1b8g_assembly1", "enzyme_name": "1-aminocyclopropane-1-carboxylate synthase", "ec": ["4.4.1.14"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P37821", "alignment_score": 833.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [2, 430], "sequence": "MRMLSRNATFNSHGQDSSYFLGWQEYEKNPYHEVHNTNGIIQMGLAENQLCFDLLESWLAKNPEAAAFKKNGESIFAELALFQDYHGLPAFKKAMVDFMAEIRGNKVTFDPNHLVLTAGATSANETFIFCLADPGEAVLIPTPYYPGFDRDLKWRTGVEIVPIHCTSSNGFQITETALEEAYQEAEKRNLRVKGVLVTNPSNPLGTTMTRNELYLLLSFVEDKGIHLISDEIYSGTAFSSPSFISVMEVLKDRNCDENSEVWQRVHVVYSLSKDLGLPGFRVGAIYSNDDMVVAAATKMSSFGLVSSQTQHLLSAMLSDKKLTKNYIAENHKRLKQRQKKLVSGLQKSGISCLNGNAGLFCWVDMRHLLRSNTFEAEMELWKKIVYEVHLNISPGSSCHCTEPGWFRVCFANLPERTLDLAMQRLKAFVGEYYNVPEVNGGSQSSHLSHSRRQSLTKWVSRLSFDDRGPIPGR", "length": 473, "reference_go_mf": ["GO:0016847", "GO:0030170", "GO:0008483"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_c737b02c06bec322fc08"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_419_1b9h_assembly1", "enzyme_name": "3-amino-5-hydroxybenzoate synthase", "ec": ["4.2.1.144"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "O52552", "alignment_score": 768.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [4, 388], "sequence": "MNARKAPEFPAWPQYDDAERNGLVRALEQGQWWRMGGDEVNSFEREFAAHHGAAHALAVTNGTHALELALQVMGVGPGTEVIVPAFTFISSSQAAQRLGAVTVPVDVDAATYNLDPEAVAAAVTPRTKVIMPVHMAGLMADMDALAKISADTGVPLLQDAAHAHGARWQGKRVGELDSIATFSFQNGKLMTAGEGGAVVFPDGETEKYETAFLRHSCGRPRDDRRYFHKIAGSNMRLNEFSASVLRAQLARLDEQIAVRDERWTLLSRLLGAIDGVVPQGGDVRADRNSHYMAMFRIPGLTEERRNALVDRLVEAGLPAFAAFRAIYRTDAFWELGAPDESVDAIARRCPNTDAISSDCVWLHHRVLLAGEPELHATAEIIADAVARA", "length": 388, "reference_go_mf": ["GO:0030170", "GO:0008483"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_46f15011b40624d25d65"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "O52552", "alignment_score": 768.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [4, 388], "sequence": "MNARKAPEFPAWPQYDDAERNGLVRALEQGQWWRMGGDEVNSFEREFAAHHGAAHALAVTNGTHALELALQVMGVGPGTEVIVPAFTFISSSQAAQRLGAVTVPVDVDAATYNLDPEAVAAAVTPRTKVIMPVHMAGLMADMDALAKISADTGVPLLQDAAHAHGARWQGKRVGELDSIATFSFQNGKLMTAGEGGAVVFPDGETEKYETAFLRHSCGRPRDDRRYFHKIAGSNMRLNEFSASVLRAQLARLDEQIAVRDERWTLLSRLLGAIDGVVPQGGDVRADRNSHYMAMFRIPGLTEERRNALVDRLVEAGLPAFAAFRAIYRTDAFWELGAPDESVDAIARRCPNTDAISSDCVWLHHRVLLAGEPELHATAEIIADAVARA", "length": 388, "reference_go_mf": ["GO:0030170", "GO:0008483"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_46f15011b40624d25d65"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_41_1dnk_assembly1", "enzyme_name": "deoxyribonuclease I", "ec": ["3.1.21.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00639", "alignment_score": 489.5, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [22, 282], "sequence": "MRGTRLMGLLLALAGLLQLGLSLKIAAFNIRTFGETKMSNATLASYIVRIVRRYDIVLIQEVRDSHLVAVGKLLDYLNQDDPNTYHYVVSEPLGRNSYKERYLFLFRPNKVSVLDTYQYDDGCESCGNDSFSREPAVVKFSSHSTKVKEFAIVALHSAPSDAVAEINSLYDVYLDVQQKWHLNDVMLMGDFNADCSYVTSSQWSSIRLRTSSTFQWLIPDSADTTATSTNCAYDRIVVAGSLLQSSVVPGSAAPFDFQAAYGLSNEMALAISDHYPVEVTLT", "length": 282, "reference_go_mf": ["GO:0004530", "GO:0003677"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_660d76f9e39ceeaf131b"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_420_1bd3_assembly1", "enzyme_name": "uracil phosphoribosyltransferase", "ec": ["2.4.2.9"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q26998", "alignment_score": 439.0, "observed_coverage": 1.0, "aligned_identity": 0.9866071428571429, "canonical_span": [20, 244], "sequence": "MAQVPASGKLLVDPRYSTNDQEESILQDIITRFPNVVLMKQTAQLRAMMTIIRDKETPKEEFVFYADRLIRLLIEEALNELPFEKKEVTTPLDVSYHGVSFYSKICGVSIVRAGESMESGLRAVCRGCRIGKILIQRDETTAEPKLIYEKLPADIRDRWVMLLDPMCATAGSVCKAIEVLLRLGVKEERIIFVNILAAPQGIERVFKEYPKVRMVTAAVDICLNSRYYIVPGIGDFGDRYFGTM", "length": 244, "reference_go_mf": ["GO:0004845"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_416d1fc6e722fad07223"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_421_1bf2_assembly1", "enzyme_name": "isoamylase", "ec": ["3.2.1.68"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P10342", "alignment_score": 1500.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [26, 776], "sequence": "MKCPKILAALLGCAVLAGVPAMPAHAAINSMSLGASYDAQQANITFRVYSSQATRIVLYLYSAGYGVQESATYTLSPAGSGVWAVTVPVSSIKAAGITGAVYYGYRAWGPNWPYASNWGKGSQAGFVSDVDANGDRFNPNKLLLDPYAQEVSQDPLNPSNQNGNVFASGASYRTTDSGIYAPKGVVLVPSTQSTGTKPTRAQKDDVIYEVHVRGFTEQDTSIPAQYRGTYYGAGLKASYLASLGVTAVEFLPVQETQNDANDVVPNSDANQNYWGYMTENYFSPDRRYAYNKAAGGPTAEFQAMVQAFHNAGIKVYMDVVYNHTAEGGTWTSSDPTTATIYSWRGLDNATYYELTSGNQYFYDNTGIGANFNTYNTVAQNLIVDSLAYWANTMGVDGFRFDLASVLGNSCLNGAYTASAPNCPNGGYNFDAADSNVAINRILREFTVRPAAGGSGLDLFAEPWAIGGNSYQLGGFPQGWSEWNGLFRDSLRQAQNELGSMTIYVTQDANDFSGSSNLFQSSGRSPWNSINFIDVHDGMTLKDVYSCNGANNSQAWPYGPSDGGTSTNYSWDQGMSAGTGAAVDQRRAARTGMAFEMLSAGTPLMQGGDEYLRTLQCNNNAYNLDSSANWLTYSWTTDQSNFYTFAQRLIAFRKAHPALRPSSWYSGSQLTWYQPSGAVADSNYWNNTSNYAIAYAINGPSLGDSNSIYVAYNGWSSSVTFTLPAPPSGTQWYRVTDTCDWNDGASTFVAPGSETLIGGAGTTYGQCGQSLLLLISK", "length": 776, "reference_go_mf": ["GO:0019156"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_68a0bbb36ab3958db186"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_422_4v40_assembly1", "enzyme_name": "beta-galactosidase", "ec": ["3.2.1.23"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00722", "alignment_score": 2042.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [3, 1024], "sequence": "MTMITDSLAVVLQRRDWENPGVTQLNRLAAHPPFASWRNSEEARTDRPSQQLRSLNGEWRFAWFPAPEAVPESWLECDLPEADTVVVPSNWQMHGYDAPIYTNVTYPITVNPPFVPTENPTGCYSLTFNVDESWLQEGQTRIIFDGVNSAFHLWCNGRWVGYGQDSRLPSEFDLSAFLRAGENRLAVMVLRWSDGSYLEDQDMWRMSGIFRDVSLLHKPTTQISDFHVATRFNDDFSRAVLEAEVQMCGELRDYLRVTVSLWQGETQVASGTAPFGGEIIDERGGYADRVTLRLNVENPKLWSAEIPNLYRAVVELHTADGTLIEAEACDVGFREVRIENGLLLLNGKPLLIRGVNRHEHHPLHGQVMDEQTMVQDILLMKQNNFNAVRCSHYPNHPLWYTLCDRYGLYVVDEANIETHGMVPMNRLTDDPRWLPAMSERVTRMVQRDRNHPSVIIWSLGNESGHGANHDALYRWIKSVDPSRPVQYEGGGADTTATDIICPMYARVDEDQPFPAVPKWSIKKWLSLPGETRPLILCEYAHAMGNSLGGFAKYWQAFRQYPRLQGGFVWDWVDQSLIKYDENGNPWSAYGGDFGDTPNDRQFCMNGLVFADRTPHPALTEAKHQQQFFQFRLSGQTIEVTSEYLFRHSDNELLHWMVALDGKPLASGEVPLDVAPQGKQLIELPELPQPESAGQLWLTVRVVQPNATAWSEAGHISAWQQWRLAENLSVTLPAASHAIPHLTTSEMDFCIELGNKRWQFNRQSGFLSQMWIGDKKQLLTPLRDQFTRAPLDNDIGVSEATRIDPNAWVERWKAAGHYQAEAALLQCTADTLADAVLITTAHAWQHQGKTLFISRKTYRIDGSGQMAITVDVEVASDTPHPARIGLNCQLAQVAERVNWLGLGPQENYPDRLTAACFDRWDLPLSDMYTPYVFPSENGLRCGTRELNYGPHQWRGDFQFNISRYSQQQLMETSHRHLLHAEEGTWLNIDGFHMGIGGDDSWSPSVSAEFQLSAGRYHYQLVWCQK", "length": 1024, "reference_go_mf": ["GO:0031420", "GO:0004565", "GO:0030246", "GO:0042802", "GO:0000287"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_d192d45958b03c26f677"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_423_1bhg_assembly1", "enzyme_name": "beta-glucuronidase", "ec": ["3.2.1.31"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P08236", "alignment_score": 1222.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [21, 632], "sequence": "MARGSAVAWAALGPLLWGCALGLQGGMLYPQESPSRECKELDGLWSFRADFSDNRRRGFEEQWYRRPLWESGPTVDMPVPSSFNDISQDWRLRHFVGWVWYEREVILPERWTQDLRTRVVLRIGSAHSYAIVWVNGVDTLEHEGGYLPFEADISNLVQVGPLPSRLRITIAINNTLTPTTLPPGTIQYLTDTSKYPKGYFVQNTYFDFFNYAGLQRSVLLYTTPTTYIDDITVTTSVEQDSGLVNYQISVKGSNLFKLEVRLLDAENKVVANGTGTQGQLKVPGVSLWWPYLMHERPAYLYSLEVQLTAQTSLGPVSDFYTLPVGIRTVAVTKSQFLINGKPFYFHGVNKHEDADIRGKGFDWPLLVKDFNLLRWLGANAFRTSHYPYAEEVMQMCDRYGIVVIDECPGVGLALPQFFNNVSLHHHMQVMEEVVRRDKNHPAVVMWSVANEPASHLESAGYYLKMVIAHTKSLDPSRPVTFVSNSNYAADKGAPYVDVICLNSYYSWYHDYGHLELIQLQLATQFENWYKKYQKPIIQSEYGAETIAGFHQDPPLMFTEEYQKSLLEQYHLGLDQKRRKYVVGELIWNFADFMTEQSPTRVLGNKKGIFTRQRQPKSAAFLLRERYWKIANETRYPHSVAKSQCLENSLFT", "length": 651, "reference_go_mf": ["GO:0004566", "GO:0030246", "GO:0019904", "GO:0005102"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_0b6cd9dfefc114e0aa72"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_424_1bjo_assembly1", "enzyme_name": "phosphoserine transaminase", "ec": ["2.6.1.52"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P23721", "alignment_score": 717.0, "observed_coverage": 1.0, "aligned_identity": 0.9972222222222222, "canonical_span": [2, 362], "sequence": "MAQIFNFSSGPAMLPAEVLKQAQQELRDWNGLGTSVMEVSHRGKEFIQVAEEAEKDFRDLLNVPSNYKVLFCHGGGRGQFAAVPLNILGDKTTADYVDAGYWAASAIKEAKKYCTPNVFDAKVTVDGLRAVKPMREWQLSDNAAYMHYCPNETIDGIAIDETPDFGADVVVAADFSSTILSRPIDVSRYGVIYAGAQKNIGPAGLTIVIVREDLLGKANIACPSILDYSILNDNGSMFNTPPTFAWYLSGLVFKWLKANGGVAEMDKINQQKAELLYGVIDNSDFYRNDVAKANRSRMNVPFQLADSALDKLFLEESFAAGLHALKGHRVVGGMRASIYNAMPLEGVKALTDFMVEFERRHG", "length": 362, "reference_go_mf": ["GO:0004648", "GO:0042803", "GO:0030170"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_6f04706d2ee823a04123"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_425_1qrz_assembly1", "enzyme_name": "plasmin", "ec": ["3.4.21.7"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00747", "alignment_score": 483.0, "observed_coverage": 1.0, "aligned_identity": 0.9878048780487805, "canonical_span": [564, 810], "sequence": "MEHKEVVLLLLLFLKSGQGEPLDDYVNTQGASLFSVTKKQLGAGSIEECAAKCEEDEEFTCRAFQYHSKEQQCVIMAENRKSSIIIRMRDVVLFEKKVYLSECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYCRNPDNDPQGPWCYTTDPEKRYDYCDILECEEECMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDRELRPWCFTTDPNKRWELCDIPRCTTPPPSSGPTYQCLKGTGENYRGNVAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDENYCRNPDGKRAPWCHTTNSQVRWEYCKIPSCDSSPVSTEQLAPTAPPELTPVVQDCYHGDGQSYRGTSSTTTTGKKCQSWSSMTPHRHQKTPENYPNAGLTMNYCRNPDADKGPWCFTTDPSVRWEYCNLKKCSGTEASVVAPPPVVLLPDVETPSEEDCMFGNGKGYRGKRATTVTGTPCQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVGGPWCYTTNPRKLYDYCDVPQCAAPSFDCGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFLEPTRKDIALLKLSSPAVITDKVIPACLPSPNYVVADRTECFITGWGETQGTFGAGLLKEAQLPVIENKVCNRYEFLNGRVQSTELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWIEGVMRNN", "length": 810, "reference_go_mf": ["GO:0034185", "GO:0004175", "GO:0019899", "GO:0019900", "GO:0002020", "GO:1990405", "GO:0019904", "GO:0051087", "GO:0004252", "GO:0008236", "GO:0005102"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_082ef6cfa8a9d5c17782"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_426_1bol_assembly1", "enzyme_name": "ribonuclease T2", "ec": ["4.6.1.19"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P08056", "alignment_score": 444.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [16, 238], "sequence": "MKAVLALATLIGSTLASSCSSTALSCSNSANSDTCCSPEYGLVVLNMQWAPGYGPDNAFTLHGLWPDKCSGAYAPSGGCDSNRASSSIASVIKSKDSSLYNSMLTYWPSNQGNNNVFWSHEWSKHGTCVSTYDPDCYDNYEEGEDIVDYFQKAMDLRSQYNVYKAFSSNGITPGGTYTATEMQSAIESYFGAKAKIDCSSGTLSDVALYFYVRGRDTYVITDALSTGSCSGDVEYPTK", "length": 238, "reference_go_mf": ["GO:0033897", "GO:0003723"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_95925666c10470887ae4"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_427_1boo_assembly1", "enzyme_name": "site-specific DNA-methyltransferase (cytosine-N4-specific)", "ec": ["2.1.1.113"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P11409", "alignment_score": 536.5, "observed_coverage": 1.0, "aligned_identity": 0.9964539007092199, "canonical_span": [15, 335], "sequence": "MMTLNLQTMSSNDMLNFGKKPAYTTSNGSMYIGDSLELLESFPDESISLVMTSPPFALQRKKEYGNLEQHEYVDWFLSFAKVVNKKLKPDGSFVVDFGGAYMKGVPARSIYNFRVLIRMIDEVGFFLAEDFYWFNPSKLPSPIEWVNKRKIRVKDAVNTVWWFSKTEWPKSDITKVLAPYSDRMKKLIEDPDKFYTPKTRPSGHDIGKSFSKDNGGSIPPNLLQISNSESNGQYLANCKLMGIKAHPARFPAKLPEFFIRMLTEPDDLVVDIFGGSNTTGLVAERESRKWISFEMKPEYVAASAFRFLDNNISEEKITDIYNRILNGESLDLNSII", "length": 336, "reference_go_mf": ["GO:0003677", "GO:0008170", "GO:0015667"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_ac105a7113693a0f70dc"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_428_1bqc_assembly1", "enzyme_name": "mannan endo-1,4-beta-mannosidase", "ec": ["3.2.1.78"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q9ZF13", "alignment_score": 552.0, "observed_coverage": 0.9238410596026491, "aligned_identity": 0.992831541218638, "canonical_span": [0, 279], "sequence": "GLHVKNGRLYEANGQEFIIRGVSHPHNWYPQHTQAFADIKSHGANTVRVVLSNGVRWSKNGPSDVANVISLCKQNRLICMLEVHDTTGYGEQSGASTLDQAVDYWIELKSVLQGEEDYVLINIGNEPYGNDSATVAAGAWDTSAAIQRLRAAGFEHTLVVDAPNWGQDWTNTMRNNADQVYASDPTGNTVFSIHMYGVYSQASTITSYLEHFVNAGLPLIIGEFGHDHSDGNPDEDTIMAEAERLKLGYIGWSWSGNGGGVEYLDMVYNFDGDNLSPWG", "length": 279, "reference_go_mf": ["GO:0016985"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_ef73ea61e486d4baa23c"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_429_1brm_assembly1", "enzyme_name": "aspartate-semialdehyde dehydrogenase", "ec": ["1.2.1.11"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0A9Q9", "alignment_score": 701.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 367], "sequence": "MKNVGFIGWRGMVGSVLMQRMVEERDFDAIRPVFFSTSQLGQAAPSFGGTTGTLQDAFDLEALKALDIIVTCQGGDYTNEIYPKLRESGWQGYWIDAASSLRMKDDAIIILDPVNQDVITDGLNNGIRTFVGGNCTVSLMLMSLGGLFANDLVDWVSVATYQAASGGGARHMRELLTQMGHLYGHVADELATPSSAILDIERKVTTLTRSGELPVDNFGVPLAGSLIPWIDKQLDNGQSREEWKGQAETNKILNTSSVIPVDGLCVRVGALRCHSQAFTIKLKKDVSIPTVEELLAAHNPWAKVVPNDREITMRELTPAAVTGTLTTPVGRLRKLNMGPEFLSAFTVGDQLLWGAAEPLRRMLRQLA", "length": 367, "reference_go_mf": ["GO:0004073", "GO:0051287", "GO:0050661", "GO:0046983"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_1c4f37549bb5f58b4c2c"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_42_1ql0_assembly1", "enzyme_name": "nuclease", "ec": ["3.1.30.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P13717", "alignment_score": 479.0, "observed_coverage": 1.0, "aligned_identity": 0.995850622406639, "canonical_span": [25, 266], "sequence": "MRFNNKMLALAALLFAAQASADTLESIDNCAVGCPTGGSSNVSIVRHAYTLNNNSTTKFANWVAYHITKDTPASGKTRNWKTDPALNPADTLAPADYTGANAALKVDRGHQAPLASLAGVSDWESLNYLSNITPQKSDLNQGAWARLEDQERKLIDRADISSVYTVTGPLYERDMGKLPGTQKAHTIPSAYWKVIFINNSPAVNHYAAFLFDQNTPKGADFCQFRVTVDEIEKRTGLIIWAGLPDDVQASLKSKPGVLPELMGCKN", "length": 266, "reference_go_mf": ["GO:0004519", "GO:0016787", "GO:0046872", "GO:0003676"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_70dfca95be2c3ae74e9f"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_430_1bs0_assembly1", "enzyme_name": "8-amino-7-oxononanoate synthase", "ec": ["2.3.1.47"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P12998", "alignment_score": 758.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 384], "sequence": "MSWQEKINAALDARRAADALRRRYPVAQGAGRWLVADDRQYLNFSSNDYLGLSHHPQIIRAWQQGAEQFGIGSGGSGHVSGYSVVHQALEEELAEWLGYSRALLFISGFAANQAVIAAMMAKEDRIAADRLSHASLLEAASLSPSQLRRFAHNDVTHLARLLASPCPGQQMVVTEGVFSMDGDSAPLAEIQQVTQQHNGWLMVDDAHGTGVIGEQGRGSCWLQKVKPELLVVTFGKGFGVSGAAVLCSSTVADYLLQFARHLIYSTSMPPAQAQALRASLAVIRSDEGDARREKLAALITRFRAGVQDLPFTLADSCSAIQPLIVGDNSRALQLAEKLRQQGCWVTAIRPPTVPAGTARLRLTLTAAHEMQDIDRLLEVLHGNG", "length": 384, "reference_go_mf": ["GO:0008710", "GO:0042803", "GO:0030170"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_e38f57b159fee1cd531f"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_431_1bs9_assembly1", "enzyme_name": "acetylxylan esterase", "ec": ["3.1.1.72"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "O59893", "alignment_score": 414.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [27, 234], "sequence": "MHSKFFAASLLGLGAAAIPLEGVMEKRSCPAIHVFGARETTASPGYGSSSTVVNGVLSAYPGSTAEAINYPACGGQSSCGGASYSSSVAQGIAAVASAVNSFNSQCPSTKIVLVGYSQGGEIMDVALCGGGDPNQGYTNTAVQLSSSAVNMVKAAIFMGDPMFRAGLSYEVGTCAAGGFDQRPAGFSCPSAAKIKSYCDASDPYCCNGSNAATHQGYGSEYGSQALAFVKSKLG", "length": 234, "reference_go_mf": ["GO:0046555"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_a73d60468131a0d8737d"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_432_1bvv_assembly1", "enzyme_name": "endo-1,4-beta-xylanase (glycosyl hydrolase 11 family)", "ec": ["3.2.1.8"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P09850", "alignment_score": 370.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [28, 213], "sequence": "MFKFKKNFLVGLSAALMSISLFSATASAASTDYWQNWTDGGGIVNAVNGSGGNYSVNWSNTGNFVVGKGWTTGSPFRTINYNAGVWAPNGNGYLTLYGWTRSPLIEYYVVDSWGTYRPTGTYKGTVKSDGGTYDIYTTTRYNAPSIDGDRTTFTQYWSVRQSKRPTGSNATITFTNHVNAWKSHGMNLGSNWAYQVMATEGYQSSGSSNVTVW", "length": 213, "reference_go_mf": ["GO:0031176"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_5bcdeb6bcf812b40aa5d"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_433_1bvz_assembly1", "enzyme_name": "neopullulanase", "ec": ["3.2.1.135"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q08751", "alignment_score": 1170.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 585], "sequence": "MLLEAIFHEAKGSYAYPISETQLRVRLRAKKGDVVRCEVLYADRYASPEEELAHALAGKAGSDERFDYFEALLECSTKRVKYVFLLTGPQGEAVYFGETGFSAERSKAGVFQYAYIHRSEVFTTPEWAKEAVIYQIFPERFANGDPSNDPPGTEQWAKDARPRHDSFYGGDLKGVIDRLPYLEELGVTALYFTPIFASPSHHKYDTADYLAIDPQFGDLPTFRRLVDEAHRRGIKIILDAVFNHAGDQFFAFRDVLQKGEQSRYKDWFFIEDFPVSKTSRTNYETFAVQVPAMPKLRTENPEVKEYLFDVARFWMEQGIDGWRLDVANEVDHAFWREFRRLVKSLNPDALIVGEIWHDASGWLMGDQFDSVMNYLFRESVIRFFATGEIHAERFDAELTRARMLYPEQAAQGLWNLLDSHDTERFLTSCGGNEAKFRLAVLFQMTYLGTPLIYYGDEIGMAGATDPDCRRPMIWEEKEQNRGLFEFYKELIRLRHRLASLTRGNVRSWHADKQANLYAFVRTVQDQHVGVVLNNRGEKQTVLLQVPESGGKTWLDCLTGEEVHGKQGQLKLTLRPYQGMILWNGR", "length": 585, "reference_go_mf": ["GO:0031216"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_91cd5a85c074330bdbce"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_434_1bwd_assembly1", "enzyme_name": "scyllo-inosamine-4-phosphate amidinotransferase", "ec": ["2.1.4.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P08078", "alignment_score": 683.0, "observed_coverage": 0.9942528735632183, "aligned_identity": 0.9971098265895953, "canonical_span": [1, 347], "sequence": "MSLVSVHNEWDPLEEVIVGTAVGARVPTADRSVFAVEYAGDYESQEQIPSGAYPDRVLKETEEELHVLAAELTKLGVTVRRPGPRDHSALIKTPDWETDGFHDYCPRDGLLSVGQTIIETPMALRSRFLESLAYKDLLLEYFASGSRWLSAPKPRLTDDSYAPQAPAGERLTDEEPVFDAANVLRFGTDLLYLVSDSGNELGAKWLQSAVGDTYTVHPCRKLYASTHVDSTIVPLRPGLVLTNPSRVNDENMPDFLRSWENITCPELVDIGFTGDKPHCSVWIGMNLLVVRPDLAVVDRRQTALIRLLEKHGMNVLPLQLTHSRTLGGGFHCATLDVRRTARETYQF", "length": 347, "reference_go_mf": ["GO:0015068", "GO:0015069"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_5e1ec0d2de93109c38e3"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_435_1bxr_assembly3", "enzyme_name": "carbamoyl-phosphate synthase (glutamine-hydrolysing)", "ec": ["6.3.5.5"], "controls": [{"chain": "A", "status": "reference_overlength", "selected": {"accession": "P00968", "alignment_score": 2146.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 1073], "sequence": "MPKRTDIKSILILGAGPIVIGQACEFDYSGAQACKALREEGYRVILVNSNPATIMTDPEMADATYIEPIHWEVVRKIIEKERPDAVLPTMGGQTALNCALELERQGVLEEFGVTMIGATADAIDKAEDRRRFDVAMKKIGLETARSGIAHTMEEALAVAADVGFPCIIRPSFTMGGSGGGIAYNREEFEEICARGLDLSPTKELLIDESLIGWKEYEMEVVRDKNDNCIIVCSIENFDAMGIHTGDSITVAPAQTLTDKEYQIMRNASMAVLREIGVETGGSNVQFAVNPKNGRLIVIEMNPRVSRSSALASKATGFPIAKVAAKLAVGYTLDELMNDITGGRTPASFEPSIDYVVTKIPRFNFEKFAGANDRLTTQMKSVGEVMAIGRTQQESLQKALRGLEVGATGFDPKVSLDDPEALTKIRRELKDAGADRIWYIADAFRAGLSVDGVFNLTNIDRWFLVQIEELVRLEEKVAEVGITGLNADFLRQLKRKGFADARLAKLAGVREAEIRKLRDQYDLHPVYKRVDTCAAEFATDTAYMYSTYEEECEANPSTDREKIMVLGGGPNRIGQGIEFDYCCVHASLALREDGYETIMVNCNPETVSTDYDTSDRLYFEPVTLEDVLEIVRIEKPKGVIVQYGGQTPLKLARALEAAGVPVIGTSPDAIDRAEDRERFQHAVERLKLKQPANATVTAIEMAVEKAKEIGYPLVVRPSYVLGGRAMEIVYDEADLRRYFQTAVSVSNDAPVLLDHFLDDAVEVDVDAICDGEMVLIGGIMEHIEQAGVHSGDSACSLPAYTLSQEIQDVMRQQVQKLAFELQVRGLMNVQFAVKNNEVYLIEVNPRAARTVPFVSKATGVPLAKVAARVMAGKSLAEQGVTKEVIPPYYSVKEVVLPFNKFPGVDPLLGPEMRSTGEVMGVGRTFAEAFAKAQLGSNSTMKKHGRALLSVREGDKERVVDLAAKLLKQGFELDATHGTAIVLGEAGINPRLVNKVHEGRPHIQDRIKNGEYTYIINTTSGRRAIEDSRVIRRSALQYKVHYDTTLNGGFATAMALNADATEKVISVQEMHAQIK", "length": 1073, "reference_go_mf": ["GO:0016597", "GO:0005524", "GO:0004087", "GO:0004088", "GO:0046872", "GO:0000166"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": [{"accession": "P0A6F1", "alignment_score": 9.0, "observed_coverage": 0.005591798695246971, "aligned_identity": 0.8333333333333334, "canonical_span": [275, 281], "length": 382, "reference_go_mf": ["GO:0005524", "GO:0004088", "GO:0004359", "GO:0046982"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}, {"chain": "B", "status": "assigned", "selected": {"accession": "P0A6F1", "alignment_score": 755.0, "observed_coverage": 1.0, "aligned_identity": 0.9973614775725593, "canonical_span": [1, 380], "sequence": "MIKSALLVLEDGTQFHGRAIGATGSAVGEVVFNTSMTGYQEILTDPSYSRQIVTLTYPHIGNVGTNDADEESSQVHAQGLVIRDLPLIASNFRNTEDLSSYLKRHNIVAIADIDTRKLTRLLREKGAQNGCIIAGDNPDAALALEKARAFPGLNGMDLAKEVTTAEAYSWTQGSWTLTGGLPEAKKEDELPFHVVAYDFGAKRNILRMLVDRGCRLTIVPAQTSAEDVLKMNPDGIFLSNGPGDPAPCDYAITAIQKFLETDIPVFGICLGHQLLALASGAKTVKMKFGHHGGNHPVKDVEKNVVMITAQNHGFAVDEATLPANLRVTHKSLFDGTLQGIHRTDKPAFSFQGHPEASPGPHDAAPLFDHFIELIEQYRKTAK", "length": 382, "reference_go_mf": ["GO:0005524", "GO:0004088", "GO:0004359", "GO:0046982"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_8438d99270ad8b240c75"}, "alternative_alignments": [{"accession": "P00968", "alignment_score": 9.0, "observed_coverage": 0.0158311345646438, "aligned_identity": 0.8333333333333334, "canonical_span": [308, 314], "length": 1073, "reference_go_mf": ["GO:0016597", "GO:0005524", "GO:0004087", "GO:0004088", "GO:0046872", "GO:0000166"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_436_1bya_assembly1", "enzyme_name": "beta-amylase", "ec": ["3.2.1.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P10538", "alignment_score": 982.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [5, 496], "sequence": "MATSDSNMLLNYVPVYVMLPLGVVNVDNVFEDPDGLKEQLLQLRAAGVDGVMVDVWWGIIELKGPKQYDWRAYRSLFQLVQECGLTLQAIMSFHQCGGNVGDIVNIPIPQWVLDIGESNHDIFYTNRSGTRNKEYLTVGVDNEPIFHGRTAIEIYSDYMKSFRENMSDFLESGLIIDIEVGLGPAGELRYPSYPQSQGWEFPRIGEFQCYDKYLKADFKAAVARAGHPEWELPDDAGKYNDVPESTGFFKSNGTYVTEKGKFFLTWYSNKLLNHGDQILDEANKAFLGCKVKLAIKVSGIHWWYKVENHAAELTAGYYNLNDRDGYRPIARMLSRHHAILNFTCLEMRDSEQPSDAKSGPQELVQQVLSGGWREDIRVAGENALPRYDATAYNQIILNAKPQGVNNNGPPKLSMFGVTYLRLSDDLLQKSNFNIFKKFVLKMHADQDYCANPQKYNHAITPLKPSAPKIPIEVLLEATKPTLPFPWLPETDMKVDG", "length": 496, "reference_go_mf": ["GO:0016161"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_c076b59fe26b94429e78"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_437_1c4x_assembly1", "enzyme_name": "2,6-dioxo-6-phenylhexa-3-enoate hydrolase", "ec": ["3.7.1.8"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q75WN8", "alignment_score": 562.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [3, 284], "sequence": "MAKTVEIIEKRFPSGTLASHALVAGDPQSPAVVLLHGAGPGAHAASNWRPIIPDLAENFFVVAPDLIGFGQSEYPETYPGHIMSWVGMRVEQILGLMNHFGIEKSHIVGNSMGGAVTLQLVVEAPERFDKVALMGSVGAPMNARPPELARLLAFYADPRLTPYRELIHSFVYDPENFPGMEEIVKSRFEVANDPEVRRIQEVMFESMKAGMESLVIPPATLGRLPHDVLVFHGRQDRIVPLDTSLYLTKHLKHAELVVLDRCGHWAQLERWDAMGPMLMEHFRAA", "length": 285, "reference_go_mf": ["GO:0003824"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_018dec7a103b1efc1c7e"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_438_1c4z_assembly1", "enzyme_name": "HECT-type E3 ubiquitin transferase", "ec": ["2.3.2.26"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q05086", "alignment_score": 700.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [519, 869], "sequence": "MEKLHQCYWKSGEPQSDDIEASRMKRAAAKHLIERYYHQLTEGCGNEACTNEFCASCPTFLRMDNNAAAIKALELYKINAKLCDPHPSKKGASSAYLENSKGAPNNSCSEIKMNKKGARIDFKDVTYLTEEKVYEILELCREREDYSPLIRVIGRVFSSAEALVQSFRKVKQHTKEELKSLQAKDEDKDEDEKEKAACSAAAMEEDSEASSSRIGDSSQGDNNLQKLGPDDVSVDIDAIRRVYTRLLSNEKIETAFLNALVYLSPNVECDLTYHNVYSRDPNYLNLFIIVMENRNLHSPEYLEMALPLFCKAMSKLPLAAQGKLIRLWSKYNADQIRRMMETFQQLITYKVISNEFNSRNLVNDDDAIVAASKCLKMVYYANVVGGEVDTNHNEEDDEEPIPESSELTLQELLGEERRNKKGPRVDPLETELGVKTLDCRKPLIPFEEFINEPLNEVLEMDKDYTFFKVETENKFSFMTCPFILNAVTKNLGLYYDNRIRMYSERRITVLYSLVQGQQLNPYLRLKVRRDHIIDDALVRLEMIAMENPADLKKQLYVEFEGEQGVDEGGVSKEFFQLVVEEIFNPDIGMFTYDESTKLFWFNPSSFETEGQFTLIGIVLGLAIYNNCILDVHFPMVVYRKLMGKKGTFRDLGDSHPVLYQSLKDLLEYEGNVEDDMMITFQISQTDLFGNPMMYDLKENGDKIPITNENRKEFVNLYSDYILNKSVEKQFKAFRRGFHMVTNESPLKYLFRPEEIELLICGSRNLDFQALEETTEYDGGYTRDSVLIREFWEIVHSFTDEQKRLFLQFTTGTDRAPVGGLGKLKMIIAKNGPDTERLPTSHTCFNVLLLPEYSSKEKLKERLLKAITYAKGFGML", "length": 875, "reference_go_mf": ["GO:0003713", "GO:0061630", "GO:0004842"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_b180a7a287fc9a95adbc"}, "alternative_alignments": [{"accession": "P68036", "alignment_score": 7.0, "observed_coverage": 0.014285714285714285, "aligned_identity": 0.8, "canonical_span": [47, 52], "length": 154, "reference_go_mf": ["GO:0019899", "GO:0003723", "GO:0003713", "GO:0061631", "GO:0031625", "GO:0097027", "GO:0004842"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}, {"chain": "B", "status": "assigned", "selected": {"accession": "P68036", "alignment_score": 288.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [3, 147], "sequence": "MAASRRLMKELEEIRKCGMKNFRNIQVDEANLLTWQGLIVPDNPPYDKGAFRIEINFPAEYPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEHPLRADLAEEYSKDRKKFCKNAEEFTKKYGEKRPVD", "length": 154, "reference_go_mf": ["GO:0019899", "GO:0003723", "GO:0003713", "GO:0061631", "GO:0031625", "GO:0097027", "GO:0004842"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_2efbdf5de663979bb828"}, "alternative_alignments": [{"accession": "Q05086", "alignment_score": 8.0, "observed_coverage": 0.027777777777777776, "aligned_identity": 1.0, "canonical_span": [360, 364], "length": 875, "reference_go_mf": ["GO:0003713", "GO:0061630", "GO:0004842"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_439_1c82_assembly1", "enzyme_name": "hyaluronate lyase", "ec": ["4.2.2.1"], "controls": [{"chain": "A", "status": "reference_overlength", "selected": {"accession": "Q54873", "alignment_score": 1414.0, "observed_coverage": 1.0, "aligned_identity": 0.9888734353268428, "canonical_span": [287, 1006], "sequence": "MQTKTKKLIVSLSSLVLSGFLLNHYMTIGAEETTTNTIQQSQKEVQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSAWVDQKNSADASTRVIEAKDGAITISSHEKLRAALHRMVPIEAKKKYKLRFKIKTDNKIGIAKVRIIEESGKDKRLWNSATTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVADQLSEDSQTDKQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKEVKKIPLKILASVKDAYTDRLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSISSQADRTYLWEKFSNYKTSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSMEWMHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDPEHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGFYQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAPLLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQCLQSLVKTIVQSDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRPSYLSAFNKMDKTAMYNAEKGFGFGLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTETDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFLGSNIQNTSTDTAATTIDQRKLESGNPYKVYVNDKEASLTEQEKDYPETQSVFLESFDSKKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNRDSYGYMLIPNVDRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVLKRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKNHSDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN", "length": 1066, "reference_go_mf": ["GO:0030246", "GO:0030340"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_43_4kbp_assembly1", "enzyme_name": "purple acid phosphatase", "ec": ["3.1.3.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P80366", "alignment_score": 845.0, "observed_coverage": 1.0, "aligned_identity": 0.9976415094339622, "canonical_span": [35, 459], "sequence": "MGVVKGLLALALVLNVVVVSNGGKSSNFVRKTNKNRDMPLDSDVFRVPPGYNAPQQVHITQGDLVGRAMIISWVTMDEPGSSAVRYWSEKNGRKRIAKGKMSTYRFFNYSSGFIHHTTIRKLKYNTKYYYEVGLRNTTRRFSFITPPQTGLDVPYTFGLIGDLGQSFDSNTTLSHYELSPKKGQTVLFVGDLSYADRYPNHDNVRWDTWGRFTERSVAYQPWIWTAGNHEIEFAPEINETEPFKPFSYRYHVPYEASQSTSPFWYSIKRASAHIIVLSSYSAYGRGTPQYTWLKKELRKVKRSETPWLIVLMHSPLYNSYNHHFMEGEAMRTKFEAWFVKYKVDVVFAGHVHAYERSERVSNIAYKITNGLCTPVKDQSAPVYITIGDAGNYGVIDSNMIQPQPEYSAFREASFGHGMFDIKNRTHAHFSWNRNQDGVAVEADSVWFFNRHWYPVDDST", "length": 459, "reference_go_mf": ["GO:0003993", "GO:0008199", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_d36de04624dbb1f00e0f"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_440_1qk2_assembly2", "enzyme_name": "cellulose 1,4-beta-cellobiosidase (non-reducing end)", "ec": ["3.2.1.91"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P07987", "alignment_score": 726.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [108, 471], "sequence": "MIVGILTTLATLATLAASVPLEERQACSSVWGQCGGQNWSGPTCCASGSTCVYSNDYYSQCLPGAASSSSSTRAASTTSRVSPTTSRSSSATPPPGSTTTRVPPVGSGTATYSGNPFVGVTPWANAYYASEVSSLAIPSLTGAMATAAAAVAKVPSFMWLDTLDKTPLMEQTLADIRTANKNGGNYAGQFVVYDLPDRDCAALASNGEYSIADGGVAKYKNYIDTIRQIVVEYSDIRTLLVIEPDSLANLVTNLGTPKCANAQSAYLECINYAVTQLNLPNVAMYLDAGHAGWLGWPANQDPAAQLFANVYKNASSPRALRGLATNVANYNGWNITSPPSYTQGNAVYNEKLYIHAIGPLLANHGWSNAFFITDQGRSGKQPTGQQQWGDWCNVIGTGFGIRPSANTGDSLLDSFVWVKPGGECDGTSDSSAPRFDSHCALPDALQPAPQAGAWFQAYFVQLLTNANPSFL", "length": 471, "reference_go_mf": ["GO:0016162", "GO:0030248", "GO:0042802"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_7292b80654d0e6f8f682"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_441_1cb8_assembly1", "enzyme_name": "chondroitin AC lyase", "ec": ["4.2.2.5"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q59288", "alignment_score": 1348.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [25, 699], "sequence": "MKKLFVTCIVFFSILSPALLIAQQTGTAELIMKRVMLDLKKPLRNMDKVAEKNLNTLQPDGSWKDVPYKDDAMTNWLPNNHLLQLETIIQAYIEKDSHYYGDDKVFDQISKAFKYWYDSDPKSRNWWHNEIATPQALGEMLILMRYGKKPLDEALVHKLTERMKRGEPEKKTGANKTDIALHYFYRALLTSDEALLSFAVKELFYPVQFVHYEEGLQYDYSYLQHGPQLQISSYGAVFITGVLKLANYVRDTPYALSTEKLAIFSKYYRDSYLKAIRGSYMDFNVEGRGVSRPDILNKKAEKKRLLVAKMIDLKHTEEWADAIARTDSTVAAGYKIEPYHHQFWNGDYVQHLRPAYSFNVRMVSKRTRRSESGNKENLLGRYLSDGATNIQLRGPEYYNIMPVWEWDKIPGITSRDYLTDRPLTKLWGEQGSNDFAGGVSDGVYGASAYALDYDSLQAKKAWFFFDKEIVCLGAGINSNAPENITTTLNQSWLNGPVISTAGKTGRGKITTFKAQGQFWLLHDAIGYYFPEGANLSLSTQSQKGNWFHINNSHSKDEVSGDVFKLWINHGARPENAQYAYIVLPGINKPEEIKKYNGTAPKVLANTNQLQAVYHQQLDMVQAIFYTAGKLSVAGIEIETDKPCAVLIKHINGKQVIWAADPLQKEKTAVLSIRDLKTGKTNRVKIDFPQQEFAGATVELK", "length": 700, "reference_go_mf": ["GO:0030246", "GO:0030341"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_fdca8bb42082caf86a77"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_442_1cbg_assembly1", "enzyme_name": "beta-glucosidase (GH1)", "ec": ["3.2.1.21"], "controls": [{"chain": "A", "status": "reference_mapping_uncertain", "selected": {"accession": "P26205", "alignment_score": 802.0, "observed_coverage": 0.8183673469387756, "aligned_identity": 1.0, "canonical_span": [11, 412], "sequence": "LLSITTTHIHAFKPLPISFDDFSDLNRSCFAPGFVFGTASSAFQYEGAAFEDGKGPSIWDTFTHKYPEKIKDRTNGDVAIDEYHRYKEDIGIMKDMNLDAYRFSISWPRVLPKGKLSGGVNREGINYYNNLINEVLANGMQPYVTLFHWDVPQALEDEYRGFLGRNIVDDFRDYAELCFKEFGDRVKHWITLNEPWGVSMNAYAYGTFAPGRCSDWLKLNCTGGDSGREPYLAAHYQLLAHAAAARLYKTKYQASQNGIIGITLVSHWFEPASKEKADVDAAKRGLDFMLGWFMHPLTKGRYPESMRYLVRKRLPKFSTEESKELTGSFDFLGLNYYSSYYAAKAPRIPNARPAIQTDSLINATFEHNGKPLGPMAASSWLCIYPQGIRKLLLYVKNHYNNPVIYITENGRNSSTINTVTSRIPF", "length": 425, "reference_go_mf": ["GO:0008422"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_443_1cc1_assembly1", "enzyme_name": "[NiFeSe] hydrogenase", "ec": ["1.12.99.6"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P13063", "alignment_score": 540.0, "observed_coverage": 1.0, "aligned_identity": 0.9963636363636363, "canonical_span": [37, 315], "sequence": "MSLSRREFVKLCSAGVAGLGISQIYHPGIVHAMTEGAKKAPVIWVQGQGCTGCSVSLLNAVHPRIKEILLDVISLEFHPTVMASEGEMALAHMYEIAEKFNGNFFLLVEGAIPTAKEGRYCIVGETLDAKGHHHEVTMMELIRDLAPKSLATVAVGTCSAYGGIPAAEGNVTGSKSVRDFFADEKIEKLLVNVPGCPPHPDWMVGTLVAAWSHVLNPTEHPLPELDDDGRPLLFFGDNIHENCPYLDKYDNSEFAETFTKPGCKAELGCKGPSTYADCAKRRWNNGINWCVENAVCIGCVEPDFPDGKSPFYVAE", "length": 315, "reference_go_mf": ["GO:0009055", "GO:0008901", "GO:0033748", "GO:0051536"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_3a089cfac3f6a2a7a0d3"}, "alternative_alignments": [{"accession": "P13065", "alignment_score": 8.0, "observed_coverage": 0.014545454545454545, "aligned_identity": 1.0, "canonical_span": [200, 204], "length": 514, "reference_go_mf": ["GO:0008901", "GO:0033748", "GO:0016151"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}, {"chain": "B", "status": "reference_nonstandard", "selected": {"accession": "P13065", "alignment_score": 963.0, "observed_coverage": 1.0, "aligned_identity": 0.9979423868312757, "canonical_span": [12, 499], "sequence": "MSQAATPAADGKVKISIDPLTRVEGHLKIEVEVKDGKVVDAKCSGGMFRGFEQILRGRDPRDSSQIVQRICGVCPTAHCTASVMAQDDAFGVKVTTNGRITRNLIFGANYLQSHILHFYHLAALDYVKGPDVSPFVPRYANADLLTDRIKDGAKADATNTYGLNQYLKALEIRRICHEMVAMFGGRMPHVQGMVVGGATEIPTADKVAEYAARFKEVQKFVIEEYLPLIYTLGSVYTDLFETGIGWKNVIAFGVFPEDDDYKTFLLKPGVYIDGKDEEFDSKLVKEYVGHSFFDHSAPGGLHYSVGETNPNPDKPGAYSFVKAPRYKDKPCEVGPLARMWVQNPELSPVGQKLLKELYGIEAKKFRDLGDKAFSIMGRHVLVAEETWLTAVAVEKWLKQVQPGAETYVKSEIPDAAEGTGFTEAPRGALLHYLKIKDKKIENYQIVSATLWNANPRDDMGQRGPIEEALIGVPVPDIKNPVNVGRLVRSYDPULGCAVHVLHAETGEEHVVNID", "length": 514, "reference_go_mf": ["GO:0008901", "GO:0033748", "GO:0016151"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": [{"accession": "P13063", "alignment_score": 8.0, "observed_coverage": 0.00823045267489712, "aligned_identity": 1.0, "canonical_span": [111, 115], "length": 315, "reference_go_mf": ["GO:0009055", "GO:0008901", "GO:0033748", "GO:0051536"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_444_1cel_assembly1", "enzyme_name": "cellulose 1,4-beta-cellobiosidase (non-reducing end)", "ec": ["3.2.1.91"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P62694", "alignment_score": 866.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [18, 451], "sequence": "MYRKLAVISAFLATARAQSACTLQSETHPPLTWQKCSSGGTCTQQTGSVVIDANWRWTHATNSSTNCYDGNTWSSTLCPDNETCAKNCCLDGAAYASTYGVTTSGNSLSIGFVTQSAQKNVGARLYLMASDTTYQEFTLLGNEFSFDVDVSQLPCGLNGALYFVSMDADGGVSKYPTNTAGAKYGTGYCDSQCPRDLKFINGQANVEGWEPSSNNANTGIGGHGSCCSEMDIWEANSISEALTPHPCTTVGQEICEGDGCGGTYSDNRYGGTCDPDGCDWNPYRLGNTSFYGPGSSFTLDTTKKLTVVTQFETSGAINRYYVQNGVTFQQPNAELGSYSGNELNDDYCTAEEAEFGGSSFSDKGGLTQFKKATSGGMVLVMSLWDDYYANMLWLDSTYPTNETSSTPGAVRGSCSTSSGVPAQVESQSPNAKVTFSNIKFGPIGSTGNPSGGNPPGGNRGTTTTRRPATTTGSSPGPTQSHYGQCGGIGYSGPTVCASGTTCQVLNPYYSQCL", "length": 513, "reference_go_mf": ["GO:0016162", "GO:0030248"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_056bea21f45a125a74d8"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_445_1cev_assembly1", "enzyme_name": "arginase", "ec": ["3.5.3.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P53608", "alignment_score": 598.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 299], "sequence": "MKPISIIGVPMDLGQTRRGVDMGPSAMRYAGVIERLERLHYDIEDLGDIPIGKAERLHEQGDSRLRNLKAVAEANEKLAAAVDQVVQRGRFPLVLGGDHSIAIGTLAGVAKHYERLGVIWYDAHGDVNTAETSPSGNIHGMPLAASLGFGHPALTQIGGYSPKIKPEHVVLIGVRSLDEGEKKFIREKGIKIYTMHEVDRLGMTRVMEETIAYLKERTDGVHLSLDLDGLDPSDAPGVGTPVIGGLTYRESHLAMEMLAEAQIITSAEFVEVNPILDERNKTASVAVALMGSLFGEKLM", "length": 299, "reference_go_mf": ["GO:0004053", "GO:0030145"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_ee6e6ec8cd494085e557"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_446_1cfr_assembly1", "enzyme_name": "type II site-specific deoxyribonuclease, Cfr10I/Bse634I", "ec": ["3.1.21.4"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P56200", "alignment_score": 566.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 283], "sequence": "MDIISKSGEGNKYTINSAIAFVAYASHIDINTTEFSKVLSGLRDFINDEAIRLGGKISDGSFNKCNGDWYEWLIGIRAIEFFLESETNFIVVKMPNATSFDVMSIYKSCLSEFIYDLRSKLSLNNVNLITSNPDFSIIDIRGRREELKSMLKDISFSNISLSTISEIDNLYKNFIDYAELEHIKSFLSVKTTFRPDRRLQLAHEGSLMKALYTHLQTRTWTINPTGIRYYAAATSIGNADVIGLKTVATHSITDVKSLPQSAVDEIFKINSVLDVDSCLSHILSS", "length": 285, "reference_go_mf": ["GO:0009036"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_fa89c2e4675e3771dc7c"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_447_1cg2_assembly1", "enzyme_name": "glutamate carboxypeptidase", "ec": ["3.4.17.11"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P06621", "alignment_score": 778.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [25, 414], "sequence": "MRPSIHRTAIAAVLATAFVAGTALAQKRDNVLFQAATDEQPAVIKTLEKLVNIETGTGDAEGIAAAGNFLEAELKNLGFTVTRSKSAGLVVGDNIVGKIKGRGGKNLLLMSHMDTVYLKGILAKAPFRVEGDKAYGPGIADDKGGNAVILHTLKLLKEYGVRDYGTITVLFNTDEEKGSFGSRDLIQEEAKLADYVLSFEPTSAGDEKLSLGTSGIAYVQVNITGKASHAGAAPELGVNALVEASDLVLRTMNIDDKAKNLRFNWTIAKAGNVSNIIPASATLNADVRYARNEDFDAAMKTLEERAQQKKLPEADVKVIVTRGRPAFNAGEGGKKLVDKAVAYYKEAGGTLGVEERTGGGTDAAYAALSGKPVIESLGLPGFGYHSDKAEYVDISAIPRRLYMAARLIMDLGAGK", "length": 415, "reference_go_mf": ["GO:0004180"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_cca19f92ad8b55dce8e4"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_448_1chk_assembly1", "enzyme_name": "chitosanase", "ec": ["3.2.1.132"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P33665", "alignment_score": 473.0, "observed_coverage": 1.0, "aligned_identity": 0.9957983193277311, "canonical_span": [40, 278], "sequence": "MHSQHRTARIALAVVLTAIPASLATAGVGYASTQASTAVKAGAGLDDPHKKEIAMELVSSAENSSLDWKAQYKYIEDIGDGRGYTGGIIGFCSGTGDMLELVQHYTDLEPGNILAKYLPALKKVNGSASHSGLGTPFTKDWATAAKDTVFQQAQNDERDRVYFDPAVSQAKADGLRALGQFAYYDAIVMHGPGNDPTSFGGIRKTAMKKARTPAQGGDETTYLNAFLDARKAAMLTEAAHDDTSRVDTEQRVFLKAGNLDLNPPLKWKTYGDPYVINS", "length": 278, "reference_go_mf": ["GO:0016977"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_84c326e04a2367829a42"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_44_1alk_assembly1", "enzyme_name": "alkaline phosphatase", "ec": ["3.1.3.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00634", "alignment_score": 883.0, "observed_coverage": 1.0, "aligned_identity": 0.9888641425389755, "canonical_span": [22, 471], "sequence": "MKQSTIALALLPLLFTPVTKARTPEMPVLENRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPLTGQYTHYALNKKTGKPDYVTDSAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKAAGLATGNVSTAELQDATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLLNARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSKNEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAANVVGLTDQTDLFYTMKAALGLK", "length": 471, "reference_go_mf": ["GO:0004035", "GO:0033748", "GO:0000287", "GO:0030613", "GO:0004721", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_2fbd9b2222475cdfbac6"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_450_1dgs_assembly1", "enzyme_name": "DNA ligase (NAD+)", "ec": ["6.5.1.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q9ZHI0", "alignment_score": 1081.5, "observed_coverage": 0.9965576592082617, "aligned_identity": 0.9706390328151986, "canonical_span": [0, 584], "sequence": "MTREEARRRINELRDLIRYHNYRYYVLADPEISDAEYDRLLRELKELEERFPEFKSPDSPTEQVGARPLEPTFRPVRHPTRMYSLDNAFTYEEVLAFEERLERALGRKRPFLYTVEHKVDGLSVNLYYEEGVLVFGATRGDGEVGEEVTQNLLTIPTIPRRLKGVPDRLEVRGEVYMPIEAFLRLNEELEERGEKVFKNPRNAAAGSLRQKDPRVTAKRGLRATFYALGLGLEESGLKSQYELLLWLKEKGFPVEHGYEKALGAEGVEEVYRRFLAQRHALPFEADGVVVKLDDLALWRELGYTARAPRFALAYKFPAEEKETRLLDVVFQVGRTGRVTPVGVLEPVFIEGSEVSRVTLHNESYIEELDIRIGDWVLVHKAGGVIPEVLRVLKERRTGEERPIRWPETCPECGHRLVKEGKVHRCPNPLCPAKRFEAIRHYASRKAMDIEGLGEKLIERLLEKGLVRDVADLYHLRKEDLLGLERMGEKSAQNLLRQIEESKHRGLERLLYALGLPGVGEVLARNLARRFGTMDRLLEASLEELLEVEEVGELTARAILETLKDPAFRDLVRRLKEAGVSMESKEEVSDLLSGLTFVLTGELSRPREEVKALLQRLGAKVTDSVSRKTSYLVVGENPGSKLEKARALGVAVLTEEEFWRFLKEKGAPVPA", "length": 670, "reference_go_mf": ["GO:0003677", "GO:0003911"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_886561aeddb8ce0b56fd"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_451_1ec9_assembly1", "enzyme_name": "glucarate dehydratase", "ec": ["4.2.1.40"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0AES2", "alignment_score": 886.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [3, 446], "sequence": "MSSQFTTPVVTEMQVIPVAGHDSMLMNLSGAHAPFFTRNIVIIKDNSGHTGVGEIPGGEKIRKTLEDAIPLVVGKTLGEYKNVLTLVRNTFADRDAGGRGLQTFDLRTTIHVVTGIEAAMLDLLGQHLGVNVASLLGDGQQRSEVEMLGYLFFVGNRKATPLPYQSQPDDSCDWYRLRHEEAMTPDAVVRLAEAAYEKYGFNDFKLKGGVLAGEEEAESIVALAQRFPQARITLDPNGAWSLNEAIKIGKYLKGSLAYAEDPCGAEQGFSGREVMAEFRRATGLPTATNMIATDWRQMGHTLSLQSVDIPLADPHFWTMQGSVRVAQMCHEFGLTWGSHSNNHFDISLAMFTHVAAAAPGKITAIDTHWIWQEGNQRLTKEPFEIKGGLVQVPEKPGLGVEIDMDQVMKAHELYQKHGLGARDDAMGMQYLIPGWTFDNKRPCMVR", "length": 446, "reference_go_mf": ["GO:0008872", "GO:0000287"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_bb2f7bf01636b6d88844"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_453_1jkm_assembly1", "enzyme_name": "Brefeldin A esterase", "ec": ["3.1.1.-"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "O68884", "alignment_score": 713.0, "observed_coverage": 1.0, "aligned_identity": 0.9972067039106145, "canonical_span": [12, 370], "sequence": "MTVTPERSTYTPPGRLGDESSGPRTDPRFSPAMVEALATFGLDEVAAAPPVSASDDLPTVLAAVGASHDGFQAVYDSIALDLPTDRDDVETSTETILGVDGNEITLHVFRPAGVEGVLPGLVYTHGGGMTILTTDNRVHRRWCTDLAAAGSVVVMVDFRNAWTAEGHHPFPSGVEDCLAAVLWVDEHRESLGLSGVVVQGESGGGNLAIATTLLAKRRGRLDAIDGVYASIPYISGGYAWDHERRLTELPSLVENDGYFIENGGMALLVRAYDPTGEHAEDPIAWPYFASEDELRGLPPFVVAVNELDPLRDEGIAFARRLARAGVDVAARVNIGLVHGADVIFRHWLPAALESTVRDVAGFAADRARLRRP", "length": 372, "reference_go_mf": ["GO:0016787"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_35a6d87e0e2cf5f5d5b1"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_454_1rpt_assembly1", "enzyme_name": "high molecular weight acid phosphatase", "ec": ["3.1.3.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P20646", "alignment_score": 681.0, "observed_coverage": 1.0, "aligned_identity": 0.9970760233918129, "canonical_span": [31, 373], "sequence": "MRAVPLHLVGTASLTLGFLLLLSLRLDPGQAKELKFVTLVFRHGDRGPIETFPNDPIKESSWPQGFGQLTKWGMGQHYELGSYIRRRYGRFLNNSYKHDQVYIRSTDVDRTLMSAMTNLAALFPPEGISIWNPRLLWQPIPVHTVSLSEDRLLYLPFRDCPRFQELKSETLKSEEFLKRLQPYKSFIDTLPSLSGFEDQDLFEIWSRLYDPLYCESVHNFTLPTWATEDAMTKLKELSELSLLSLYGIHKQKEKSRLQGGVLVNEILKNMKLATQPQKARKLIMYSAHDTTVSGLQMALDVYNGLLPPYASCHIMELYQDNGGHFVEMYYRNETQNEPYPLTLPGCTHSCPLEKFAELLDPVIPQDWATECMGTSNHQASL", "length": 381, "reference_go_mf": ["GO:0008253", "GO:0003993", "GO:0033265", "GO:0042802", "GO:0052642", "GO:0060090", "GO:0016791", "GO:0042803", "GO:0004725", "GO:0042131"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_c0f477942db7d94915a9"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_455_3eca_assembly1", "enzyme_name": "asparaginase", "ec": ["3.5.1.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00805", "alignment_score": 640.0, "observed_coverage": 1.0, "aligned_identity": 0.9877300613496932, "canonical_span": [22, 348], "sequence": "MEFFKKTALAALVMGFSGAALALPNITILATGGTIAGGGDSATKSNYTVGKVGVENLVNAVPQLKDIANVKGEQVVNIGSQDMNDNVWLTLAKKINTDCDKTDGFVITHGTDTMEETAYFLDLTVKCDKPVVMVGAMRPSTSMSADGPFNLYNAVVTAADKASANRGVLVVMNDTVLDGRDVTKTNTTDVATFKSVNYGPLGYIHNGKIDYQRTPARKHTSDTPFDVSKLNELPKVGIVYNYANASDLPAKALVDAGYDGIVSAGVGNGNLYKSVFDTLATAAKTGTAVVRSSRVPTGATTQDAEVDDAKYGFVASGTLNPQKARVLLQLALTQTKDPQQIQQIFNQY", "length": 348, "reference_go_mf": ["GO:0004067", "GO:0042802"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_f21f7537936dc4ec9c94"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P00805", "alignment_score": 640.0, "observed_coverage": 1.0, "aligned_identity": 0.9877300613496932, "canonical_span": [22, 348], "sequence": "MEFFKKTALAALVMGFSGAALALPNITILATGGTIAGGGDSATKSNYTVGKVGVENLVNAVPQLKDIANVKGEQVVNIGSQDMNDNVWLTLAKKINTDCDKTDGFVITHGTDTMEETAYFLDLTVKCDKPVVMVGAMRPSTSMSADGPFNLYNAVVTAADKASANRGVLVVMNDTVLDGRDVTKTNTTDVATFKSVNYGPLGYIHNGKIDYQRTPARKHTSDTPFDVSKLNELPKVGIVYNYANASDLPAKALVDAGYDGIVSAGVGNGNLYKSVFDTLATAAKTGTAVVRSSRVPTGATTQDAEVDDAKYGFVASGTLNPQKARVLLQLALTQTKDPQQIQQIFNQY", "length": 348, "reference_go_mf": ["GO:0004067", "GO:0042802"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_f21f7537936dc4ec9c94"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_456_1d5r_assembly1", "enzyme_name": "dual-specificity phosphatase", "ec": ["3.1.3.16"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P60484", "alignment_score": 593.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [13, 351], "sequence": "MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSYLLKNHLDYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPTRREDKFMYFEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEIDSICSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEASSSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEDQHTQITKV", "length": 403, "reference_go_mf": ["GO:0010997", "GO:0008013", "GO:0019899", "GO:0042802", "GO:0030351", "GO:0051717", "GO:0140678", "GO:0030165", "GO:0052866", "GO:0016314", "GO:0051800", "GO:0004438", "GO:0004721", "GO:0004722", "GO:0004725", "GO:1990757", "GO:1990381"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_2675a6cc946076d70342"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_457_1g6t_assembly1", "enzyme_name": "3-phosphoshikimate 1-carboxyvinyltransferase", "ec": ["2.5.1.19"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0A6D3", "alignment_score": 854.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 427], "sequence": "MESLTLQPIARVDGTINLPGSKSVSNRALLLAALAHGKTVLTNLLDSDDVRHMLNALTALGVSYTLSADRTRCEIIGNGGPLHAEGALELFLGNAGTAMRPLAAALCLGSNDIVLTGEPRMKERPIGHLVDALRLGGAKITYLEQENYPPLRLQGGFTGGNVDVDGSVSSQFLTALLMTAPLAPEDTVIRIKGDLVSKPYIDITLNLMKTFGVEIENQHYQQFVVKGGQSYQSPGTYLVEGDASSASYFLAAAAIKGGTVKVTGIGRNSMQGDIRFADVLEKMGATICWGDDYISCTRGELNAIDMDMNHIPDAAMTIATAALFAKGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVEEGHDYIRITPPEKLNFAEIATYNDHRMAMCFSLVALSDTPVTILDPKCTAKTFPDYFEQLARISQAA", "length": 427, "reference_go_mf": ["GO:0003866"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_294f248b366a8a06a5a6"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_458_1a4i_assembly1", "enzyme_name": "methenyltetrahydrofolate cyclohydrolase", "ec": ["3.5.4.9"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P11586", "alignment_score": 556.5, "observed_coverage": 1.0, "aligned_identity": 0.9964912280701754, "canonical_span": [1, 296], "sequence": "MAPAEILNGKEISAQIRARLKNQVTQLKEQVPGFTPRLAILQVGNRDDSNLYINVKLKAAEEIGIKATHIKLPRTTTESEVMKYITSLNEDSTVHGFLVQLPLDSENSINTEEVINAIAPEKDVDGLTSINAGKLARGDLNDCFIPCTPKGCLELIKETGVPIAGRHAVVVGRSKIVGAPMHDLLLWNNATVTTCHSKTAHLDEEVNKGDILVVATGQPEMVKGEWIKPGAIVIDCGINYVPDDKKPNGRKVVGDVAYDEAKERASFITPVPGGVGPMTVAMLMQSTVESAKRFLEKFKPGKWMIQYNNLNLKTPVPSDIDISRSCKPKPIGKLAREIGLLSEEVELYGETKAKVLLSALERLKHRPDGKYVVVTGITPTPLGEGKSTTTIGLVQALGAHLYQNVFACVRQPSQGPTFGIKGGAAGGGYSQVIPMEEFNLHLTGDIHAITAANNLVAAAIDARIFHELTQTDKALFNRLVPSVNGVRRFSDIQIRRLKRLGIEKTDPTTLTDEEINRFARLDIDPETITWQRVLDTNDRFLRKITIGQAPTEKGHTRTAQFDISVASEIMAVLALTTSLEDMRERLGKMVVASSKKGEPVSAEDLGVSGALTVLMKDAIKPNLMQTLEGTPVFVHAGPFANIAHGNSSIIADRIALKLVGPEGFVVTEAGFGADIGMEKFFNIKCRYSGLCPHVVVLVATVRALKMHGGGPTVTAGLPLPKAYIQENLELVEKGFSNLKKQIENARMFGIPVVVAVNAFKTDTESELDLISRLSREHGAFDAVKCTHWAEGGKGALALAQAVQRAAQAPSSFQLLYDLKLPVEDKIRIIAQKIYGADDIELLPEAQHKAEVYTKQGFGNLPICMAKTHLSLSHNPEQKGVPTGFILPIRDIRASVGAGFLYPLVGTMSTMPGLPTRPCFYDIDLDPETEQVNGLF", "length": 935, "reference_go_mf": ["GO:0005524", "GO:0004329", "GO:0004477", "GO:0004488"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_748e6e336c8e454791e2"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_459_1pyl_assembly1", "enzyme_name": "guanyl-specific ribonuclease Sa", "ec": ["3.1.27.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q53752", "alignment_score": 192.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [67, 163], "sequence": "MTRSKSPLVVGAVLILAVLAGVGYLLAGRGGSTHPKAAASSAAAGTSAPKSSAPKPSPPAGGAWTPADPALADVCRTKLPSQAQDTLALIAKNGPYPYNRDGVVFENRESRLPKKGNGYYHEFTVVTPGSNDRGTRRVVTGGYGEQYWSPDHYATFQEIDPRC", "length": 163, "reference_go_mf": ["GO:0003723", "GO:0004521"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_e3546824e165d9a3930c"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_45_1cdg_assembly1", "enzyme_name": "cyclomaltodextrin glucanotransferase", "ec": ["2.4.1.19"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P43379", "alignment_score": 1372.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [27, 713], "sequence": "MKKFLKSTAALALGLSLTFGLFSPAQAAPDTSVSNKQNFSTDVIYQIFTDRFSDGNPANNPTGAAFDGTCTNLRLYCGGDWQGIINKINDGYLTGMGVTAIWISQPVENIYSIINYSGVNNTAYHGYWARDFKKTNPAYGTIADFQNLIAAAHAKNIKVIIDFAPNHTSPASSDQPSFAENGRLYDNGTLLGGYTNDTQNLFHHNGGTDFSTTENGIYKNLYDLADLNHNNSTVDVYLKDAIKMWLDLGIDGIRMDAVKHMPFGWQKSFMAAVNNYKPVFTFGEWFLGVNEVSPENHKFANESGMSLLDFRFAQKVRQVFRDNTDNMYGLKAMLEGSAADYAQVDDQVTFIDNHDMERFHASNANRRKLEQALAFTLTSRGVPAIYYGTEQYMSGGTDPDNRARIPSFSTSTTAYQVIQKLAPLRKCNPAIAYGSTQERWINNDVLIYERKFGSNVAVVAVNRNLNAPASISGLVTSLPQGSYNDVLGGLLNGNTLSVGSGGAASNFTLAAGGTAVWQYTAATATPTIGHVGPMMAKPGVTITIDGRGFGSSKGTVYFGTTAVSGADITSWEDTQIKVKIPAVAGGNYNIKVANAAGTASNVYDNFEVLSGDQVSVRFVVNNATTALGQNVYLTGSVSELGNWDPAKAIGPMYNQVVYQYPNWYYDVSVPAGKTIEFKFLKKQGSTVTWEGGSNHTFTAPSSGTATINVNWQP", "length": 713, "reference_go_mf": ["GO:0004556", "GO:0043169", "GO:0043895", "GO:2001070"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_8ad128a01756a31fcff3"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_460_1myr_assembly1", "enzyme_name": "thioglucosidase", "ec": ["3.2.1.147"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P29736", "alignment_score": 926.0, "observed_coverage": 1.0, "aligned_identity": 0.9519038076152304, "canonical_span": [2, 501], "sequence": "DEEITCQENLPFTCGNTDALNSSSFSSDFIFGVASSAYQIEGTIGRGLNIWDGFTHRYPNKSGPDHGNGDTTCDSFSYWQKDIDVLDELNATGYRFSIAWSRIIPRGKRSRGVNEKGIDYYHGLISGLIKKGITPFVTLFHWDLPQTLQDEYEGFLDPQIIDDFKDYADLCFEEFGDSVKYWLTINQLYSVPTRGYGSALDAPGRCSPTVDPSCYAGNSSTEPYIVAHHQLLAHAKVVDLYRKNYTHQGGKIGPTMITRWFLPYNDTDRHSIAATERMKEFFLGWFMGPLTNGTYPQIMIDTVGERLPSFSPEESNLVKGSYDFLGLNYYFTQYAQPSPNPVNSTNHTAMMDAGAKLTYINASGHYIGPLFEKDKADSTDNIYYYPKGIYSVMDYFKNKYYNPLIYVTENGISTPGDENRNQSMLDYTRIDYLCSHLCFLNKVIKEKDVNVKGYLAWALGDNYEFNKGFTVRFGLSYIDWNNVTDRDLKKSGQWYQSFISP", "length": 501, "reference_go_mf": ["GO:0008422", "GO:0019137"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_6ddda142c99f49cc3dc6"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_461_1s9c_assembly1", "enzyme_name": "enoyl-CoA hydratase", "ec": ["4.2.1.119"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P51659", "alignment_score": 460.5, "observed_coverage": 1.0, "aligned_identity": 0.9959677419354839, "canonical_span": [326, 606], "sequence": "MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRAGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL", "length": 736, "reference_go_mf": ["GO:0106386", "GO:0003857", "GO:0018812", "GO:0033989", "GO:0004300", "GO:0004303", "GO:0042803", "GO:0102158"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_fe07ad8dc6b7afa8886d"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_462_1pnt_assembly1", "enzyme_name": "low molecular weight phosphotyrosine protein phosphatase", "ec": ["3.1.3.48"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P11064", "alignment_score": 314.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 158], "sequence": "MAEQVTKSVLFVCLGNICRSPIAEAVFRKLVTDQNISDNWVIDSGAVSDWNVGRSPDPRAVSCLRNHGINTAHKARQVTKEDFVTFDYILCMDESNLRDLNRKSNQVKNCRAKIELLGSYDPQKQLIIEDPYYGNDADFETVYQQCVRCCRAFLEKVR", "length": 158, "reference_go_mf": ["GO:0003993", "GO:0004726", "GO:0004725"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_91068c059f48fd2925bb"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_463_2dw7_assembly1", "enzyme_name": "D(-)-tartrate dehydratase", "ec": ["4.2.1.81"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q89FH0", "alignment_score": 776.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 389], "sequence": "MSVRIVDVREITKPISSPIRNAYIDFTKMTTSLVAVVTDVVREGKRVVGYGFNSNGRYGQGGLIRERFASRILEADPKKLLNEAGDNLDPDKVWAAMMINEKPGGHGERSVAVGTIDMAVWDAVAKIAGKPLFRLLAERHGVKANPRVFVYAAGGYYYPGKGLSMLRGEMRGYLDRGYNVVKMKIGGAPIEEDRMRIEAVLEEIGKDAQLAVDANGRFNLETGIAYAKMLRDYPLFWYEEVGDPLDYALQAALAEFYPGPMATGENLFSHQDARNLLRYGGMRPDRDWLQFDCALSYGLCEYQRTLEVLKTHGWSPSRCIPHGGHQMSLNIAAGLGLGGNESYPDLFQPYGGFPDGVRVENGHITMPDLPGIGFEGKSDLYKEMKALAE", "length": 389, "reference_go_mf": ["GO:0047808", "GO:0016836", "GO:0000287"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_92eb2573eae574dc028d"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_464_1teh_assembly2", "enzyme_name": "alcohol dehydrogenase (class III)", "ec": ["1.1.1.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P11766", "alignment_score": 746.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 374], "sequence": "MANEVIKCKAAVAWEAGKPLSIEEIEVAPPKAHEVRIKIIATAVCHTDAYTLSGADPEGCFPVILGHEGAGIVESVGEGVTKLKAGDTVIPLYIPQCGECKFCLNPKTNLCQKIRVTQGKGLMPDGTSRFTCKGKTILHYMGTSTFSEYTVVADISVAKIDPLAPLDKVCLLGCGISTGYGAAVNTAKLEPGSVCAVFGLGGVGLAVIMGCKVAGASRIIGVDINKDKFARAKEFGATECINPQDFSKPIQEVLIEMTDGGVDYSFECIGNVKVMRAALEACHKGWGVSVVVGVAASGEEIATRPFQLVTGRTWKGTAFGGWKSVESVPKLVSEYMSKKIKVDEFVTHNLSFDEINKAFELMHSGKSIRTVVKI", "length": 374, "reference_go_mf": ["GO:0004022", "GO:0009055", "GO:0005504", "GO:0018467", "GO:0050061", "GO:0106322", "GO:0106321", "GO:0051903", "GO:0080007", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_ed8a1691faf6bd8eac04"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_465_1ju3_assembly1", "enzyme_name": "cocaine esterase", "ec": ["3.1.1.84"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q9L9D7", "alignment_score": 1140.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [4, 574], "sequence": "MVDGNYSVASNVMVPMRDGVRLAVDLYRPDADGPVPVLLVRNPYDKFDVFAWSTQSTNWLEFVRDGYAVVIQDTRGLFASEGEFVPHVDDEADAEDTLSWILEQAWCDGNVGMFGVSYLGVTQWQAAVSGVGGLKAIAPSMASADLYRAPWYGPGGALSVEALLGWSALIGTGLITSRSDARPEDAADFVQLAAILNDVAGAASVTPLAEQPLLGRLIPWVIDQVVDHPDNDESWQSISLFERLGGLATPALITAGWYDGFVGESLRTFVAVKDNADARLVVGPWSHSNLTGRNADRKFGIAATYPIQEATTMHKAFFDRHLRGETDALAGVPKVRLFVMGIDEWRDETDWPLPDTAYTPFYLGGSGAANTSTGGGTLSTSISGTESADTYLYDPADPVPSLGGTLLFHNGDNGPADQRPIHDRDDVLCYSTEVLTDPVEVTGTVSARLFVSSSAVDTDFTAKLVDVFPDGRAIALCDGIVRMRYRETLVNPTLIEAGEIYEVAIDMLATSNVFLPGHRIMVQVSSSNFPKYDRNSNTGGVIAREQLEEMCTAVNRIHRGPEHPSHIVLPIIKR", "length": 574, "reference_go_mf": ["GO:0008239"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_e62638d3f9548a7eb25b"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_466_1ci8_assembly1", "enzyme_name": "fusarinine-C ornithinesterase", "ec": ["3.1.1.48"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q9KX40", "alignment_score": 754.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [14, 391], "sequence": "MTAASLDPTAFSLDAASLAARLDAVFDQALRERRLVGAVAIVARHGEILYRRAQGLADREAGRPMREDTLFRLASVTKPIVALAVLRLVARGELALDAPVTRWLPEFRPRLADGSEPLVTIHHLLTHTSGLGYWLLEGAGSVYDRLGISDGIDLRDFDLDENLRRLASAPLSFAPGSGWQYSLALDVLGAVVERATGQPLAAAVDALVAQPLGMRDCGFVSAEPERFAVPYHDGQPEPVRMRDGIEVPLPEGHGAAVRFAPSRVFEPGAYPSGGAGMYGSADDVLRALEAIRANPGFLPETLADAARRDQAGVGAETRGPGWGFGYLSAVLDDPAAAGTPQHAGTLQWGGVYGHSWFVDRALGLSVLLLTNTAYEGMSGPLTIALRDAVYAR", "length": 392, "reference_go_mf": [], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_b73c92b6a52927b78199"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_467_1cv2_assembly1", "enzyme_name": "haloalkane dehalogenase (subfamily 2)", "ec": ["3.8.1.5"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "D4Z2G1", "alignment_score": 586.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [3, 296], "sequence": "MSLGAKPFGEKKFIEIKGRRMAYIDEGTGDPILFQHGNPTSSYLWRNIMPHCAGLGRLIACDLIGMGDSDKLDPSGPERYAYAEHRDYLDALWEALDLGDRVVLVVHDWGSALGFDWARRHRERVQGIAYMEAIAMPIEWADFPEQDRDLFQAFRSQAGEELVLQDNVFVEQVLPGLILRPLSEAEMAAYREPFLAAGEARRPTLSWPRQIPIAGTPADVVAIARDYAGWLSESPIPKLFINAEPGALTTGRMRDFCRTWPNQTEITVAGAHFIQEDSPDEIGAAIAAFVRRLRPA", "length": 296, "reference_go_mf": ["GO:0018786"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_e67b2509cf424b88b5b2"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_468_1kcz_assembly1", "enzyme_name": "methylaspartate ammonia-lyase", "ec": ["4.3.1.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q05514", "alignment_score": 818.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 413], "sequence": "MKIVDVLCTPGLTGFYFDDQRAIKKGAGHDGFTYTGSTVTEGFTQVRQKGESISVLLVLEDGQVAHGDCAAVQYSGAGGRDPLFLAKDFIPVIEKEIAPKLIGREITNFKPMAEEFDKMTVNGNRLHTAIRYGITQAILDAVAKTRKVTMAEVIRDEYNPGAEINAVPVFAQSGDDRYDNVDKMIIKEADVLPHALINNVEEKLGLKGEKLLEYVKWLRDRIIKLRVREDYAPIFHIDVYGTIGAAFDVDIKAMADYIQTLAEAAKPFHLRIEGPMDVEDRQKQMEAMRDLRAELDGRGVDAELVADEWCNTVEDVKFFTDNKAGHMVQIKTPDLGGVNNIADAIMYCKANGMGAYCGGTCNETNRSAEVTTNIGMACGARQVLAKPGMGVDEGMMIVKNEMNRVLALVGRRK", "length": 413, "reference_go_mf": ["GO:0050096"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_38cf97e4bbad597432c4"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_469_1bzc_assembly1", "enzyme_name": "protein-tyrosine-phosphatase non-receptor type 1", "ec": ["3.1.3.48"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P18031", "alignment_score": 588.0, "observed_coverage": 1.0, "aligned_identity": 0.9932659932659933, "canonical_span": [1, 298], "sequence": "MEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHEDLEPPPEHIPPPPRPPKRILEPHNGKCREFFPNHQWVKEETQEDKDCPIKEEKGSPLNAAPYGIESMSQDTEVRSRVVGGSLRGAQAASPAKGEPSLPEKDEDHALSYWKPFLVNMCVATVLTAGAYLCYRFLFNSNT", "length": 435, "reference_go_mf": ["GO:0045296", "GO:0019899", "GO:0046875", "GO:0005158", "GO:0004726", "GO:0004721", "GO:0019901", "GO:0051721", "GO:0004725", "GO:0030971", "GO:0003723", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_c5eb9a7d07a45a0c584c"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_46_2adm_assembly1", "enzyme_name": "site-specific DNA-methyltransferase (adenine-specific)", "ec": ["2.1.1.72"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P14385", "alignment_score": 754.5, "observed_coverage": 1.0, "aligned_identity": 0.9948051948051948, "canonical_span": [20, 413], "sequence": "MGLPPLLSLPSNSAPRSLGRVETPPEVVDFMVSLAEAPRGGRVLEPACAHGPFLRAFREAHGTAYRFVGVEIDPKALDLPPWAEGILADFLLWEPGEAFDLILGNPPYGIVGEASKYPIHVFKAVKDLYKKAFSTWKGKYNLYGAFLEKAVRLLKPGGVLVFVVPATWLVLEDFALLREFLAREGKTSVYYLGEVFPQKKVSAVVIRFQKSGKGLSLWDTQESESGFTPILWAEYPHWEGEIIRFETEETRKLEISGMPLGDLFHIRFAARSPEFKKHPAVRKEPGPGLVPVLTGRNLKPGWVDYEKNHSGLWMPKERAKELRDFYATPHLVVAHTKGTRVVAAWDERAYPWREEFHLLPKEGVRLDPSSLVQWLNSEAMQKHVRTLYRDFVPHLTLRMLERLPVRREYGFHTSPESARNF", "length": 421, "reference_go_mf": ["GO:0003676", "GO:0009007"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_f2cc958bb7c9d402a621"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_471_1hoz_assembly1", "enzyme_name": "inosine, adenosine, and guanine nucleoside hydrolase", "ec": ["3.2.2.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q9GPQ4", "alignment_score": 613.5, "observed_coverage": 0.9936708860759493, "aligned_identity": 0.9968152866242038, "canonical_span": [1, 327], "sequence": "MAKNVVLDHDGNLDDFVAMVLLASNTEKVRLIGALCTDADCFVENGFNVTGKIMCLMHNNMNLPLFPIGKSAATAVNPFPKEWRCLAKNMDDMPILNIPENVELWDKIKAENEKYEGQQLLADLVMNSEEKVTICVTGPLSNVAWCIDKYGEKFTSKVEECVIMGGAVDVRGNVFLPSTDGTAEWNIYWDPASAKTVFGCPGLRRIMFSLDSTNTVPVRSPYVQRFGEQTNFLLSILVGTMWAMCTHCELLRDGDGYYAWDALTAAYVVDQKVANVDPVPIDVVVDKQPNEGATVRTDAEKYPLTFVARNPEAEFFLDMLLRSARAC", "length": 327, "reference_go_mf": ["GO:0008477"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_c6565b133c27389562e1"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_472_1s95_assembly1", "enzyme_name": "serine/threonine-protein phosphatase 5", "ec": ["3.1.3.16"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P53041", "alignment_score": 648.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [175, 499], "sequence": "MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQLGMM", "length": 499, "reference_go_mf": ["GO:0043531", "GO:0005524", "GO:0001965", "GO:0030544", "GO:0051879", "GO:0042802", "GO:0008017", "GO:0031435", "GO:0016791", "GO:0004721", "GO:0030291", "GO:0004722", "GO:0044877", "GO:0003723", "GO:0048156"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_f486bd8745bc94336c6e"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_473_1xqd_assembly1", "enzyme_name": "NADP nitrous oxide-forming nitric oxide reductase", "ec": ["1.7.1.14"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P23295", "alignment_score": 789.0, "observed_coverage": 1.0, "aligned_identity": 0.9924812030075187, "canonical_span": [4, 403], "sequence": "MASGAPSFPFSRASGPEPPAEFAKLRATNPVSQVKLFDGSLAWLVTKHKDVCFVATSEKLSKVRTRQGFPELSASGKQAAKAKPTFVDMDPPEHMHQRSMVEPTFTPEAVKNLQPYIQRTVDDLLEQMKQKGCANGPVDLVKEFALPVPSYIIYTLLGVPFNDLEYLTQQNAIRTNGSSTAREASAANQELLDYLAILVEQRLVEPKDDIISKLCTEQVKPGNIDKSDAVQIAFLLLVAGNATMVNMIALGVATLAQHPDQLAQLKANPSLAPQFVEELCRYHTASALAIKRTAKEDVMIGDKLVRANEGIIASNQSANRDEEVFENPDEFNMNRKWPPQDPLGFGFGDHRCIAEHLAKAELTTVFSTLYQKFPDLKVAVPLGKINYTPLNRDVGIVDLPVIF", "length": 403, "reference_go_mf": ["GO:0020037", "GO:0005506", "GO:0004497", "GO:0102199", "GO:0016705"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_d20211cab68451ecad77"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_474_3zo8_assembly1", "enzyme_name": "chorismate mutase (AroH)", "ec": ["5.4.99.5"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P19080", "alignment_score": 231.0, "observed_coverage": 1.0, "aligned_identity": 0.9914529914529915, "canonical_span": [0, 117], "sequence": "MMIRGIRGATTVERDTEEEILQKTKQLLEKIIEENHTKPEDVVQMLLSATPDLHAVFPAKAVRELSGWQYVPVTCMQEMDVTGGLKKCIRVMMTVQTDVPQDQIRHVYLEKVVVLRPDLSLTKNTEL", "length": 127, "reference_go_mf": ["GO:0004106"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_d9dac11c0df83c0a0326"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P19080", "alignment_score": 231.0, "observed_coverage": 1.0, "aligned_identity": 0.9914529914529915, "canonical_span": [0, 117], "sequence": "MMIRGIRGATTVERDTEEEILQKTKQLLEKIIEENHTKPEDVVQMLLSATPDLHAVFPAKAVRELSGWQYVPVTCMQEMDVTGGLKKCIRVMMTVQTDVPQDQIRHVYLEKVVVLRPDLSLTKNTEL", "length": 127, "reference_go_mf": ["GO:0004106"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_d9dac11c0df83c0a0326"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_476_1cqj_assembly1", "enzyme_name": "succinate---CoA ligase (ADP-forming)", "ec": ["6.2.1.5"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0AGE9", "alignment_score": 572.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 287], "sequence": "MSILIDKNTKVICQGFTGSQGTFHSEQAIAYGTKMVGGVTPGKGGTTHLGLPVFNTVREAVAATGATASVIYVPAPFCKDSILEAIDAGIKLIITITEGIPTLDMLTVKVKLDEAGVRMIGPNCPGVITPGECKIGIQPGHIHKPGKVGIVSRSGTLTYEAVKQTTDYGFGQSTCVGIGGDPIPGSNFIDILEMFEKDPQTEAIVMIGEIGGSAEEEAAAYIKEHVTKPVVGYIAGVTAPKGKRMGHAGAIIAGGKGTADEKFAALEAAGVKTVRSLADIGEALKTVLK", "length": 289, "reference_go_mf": ["GO:0004775", "GO:0004776"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_7014364ce2436222b721"}, "alternative_alignments": [{"accession": "P0A836", "alignment_score": 11.0, "observed_coverage": 0.045454545454545456, "aligned_identity": 0.6153846153846154, "canonical_span": [56, 69], "length": 388, "reference_go_mf": ["GO:0005524", "GO:0000287", "GO:0004775", "GO:0004776"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}, {"chain": "B", "status": "assigned", "selected": {"accession": "P0A836", "alignment_score": 770.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 385], "sequence": "MNLHEYQAKQLFARYGLPAPVGYACTTPREAEEAASKIGAGPWVVKCQVHAGGRGKAGGVKVVNSKEDIRAFAENWLGKRLVTYQTDANGQPVNQILVEAATDIAKELYLGAVVDRSSRRVVFMASTEGGVEIEKVAEETPHLIHKVALDPLTGPMPYQGRELAFKLGLEGKLVQQFTKIFMGLATIFLERDLALIEINPLVITKQGDLICLDGKLGADGNALFRQPDLREMRDQSQEDPREAQAAQWELNYVALDGNIGCMVNGAGLAMGTMDIVKLHGGEPANFLDVGGGATKERVTEAFKIILSDDKVKAVLVNIFGGIVRCDLIADGIIGAVAEVGVNVPVVVRLEGNNAELGAKKLADSGLNIIAAKGLTDAAQQVVAAVEGK", "length": 388, "reference_go_mf": ["GO:0005524", "GO:0000287", "GO:0004775", "GO:0004776"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_45ade08b7e1c25f8bc50"}, "alternative_alignments": [{"accession": "P0AGE9", "alignment_score": 11.0, "observed_coverage": 0.033766233766233764, "aligned_identity": 0.6153846153846154, "canonical_span": [267, 280], "length": 289, "reference_go_mf": ["GO:0004775", "GO:0004776"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_477_1cqq_assembly1", "enzyme_name": "picornain 3C", "ec": ["3.4.22.28"], "controls": [{"chain": "A", "status": "reference_overlength", "selected": {"accession": "P04936", "alignment_score": 360.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1507, 1687], "sequence": "MGAQVSRQNVGTHSTQNSVSNGSSLNYFNINYFKDAASNGASKLEFTQDPSKFTDPVKDVLEKGIPTLQSPTVEACGYSDRIIQITRGDSTITSQDVANAIVAYGVWPHYLSSKDASAIDKPSQPDTSSNRFYTLRSVTWSSSSKGWWWKLPDALKDMGIFGENMFYHYLGRSGYTIHVQCNASKFHQGTLIVALIPEHQIASALHGNVNVGYNYTHPGETGREVKAETRLNPDLQPTEEYWLNFDGTLLGNITIFPHQFINLRSNNSATIIAPYVNAVPMDSMRSHNNWSLVIIPICPLETSSAINTIPITISISPMCAEFSGARAKRQGLPVFITPGSGQFLTTDDFQSPCALPWYHPTKEISIPGEVKNLVEICQVDSLVPINNTDTYINSENMYSVVLQSSINAPDKIFSIRTDVASQPLATTLIGEISSYFTHWTGSLRFSFMFCGTANTTVKLLLAYTPPGIAEPTTRKDAMLGTHVIWDVGLQSTISMVVPWISASHYRNTSPGRSTSGYITCWYQTRLVIPPQTPPTARLLCFVSGCKDFCLRMARDTNLHLQSGAIAQNPVENYIDEVLNEVLVVPNINSSNPTTSNSAPALDAAETGHTSSVQPEDVIETRYVQTSQTRDEMSLESFLGRSGCIHESKLEVTLANYNKENFTVWAINLQEMAQIRRKFELFTYTRFDSEITLVPCISALSQDIGHITMQYMYVPPGAPVPNSRDDYAWQSGTNASVFWQHGQAYPRFSLPFLSVASAYYMFYDGYDEQDQNYGTANTNNMGSLCSRIVTEKHIHKVHIMTRIYHKAKHVKAWCPRPPRALEYTRAHRTNFKIEDRSIQTAIVTRPIITTAGPSDMYVHVGNLIYRNLHLFNSEMHESILVSYSSDLIIYRTNTVGDDYIPSCDCTQATYYCKHKNRYFPITVTSHDWYEIQESEYYPKHIQYNLLIGEGPCEPGDCGGKLLCKHGVIGIVTAGGDNHVAFIDLRHFHCAEEQGVTDYIHMLGEAFGNGFVDSVKEHIHAINPVGNISKKIIKWMLRIISAMVIIIRNSSDPQTILATLTLIGCSGSPWRFLKEKFCKWTQLNYIHKESDSWLKKFTEACNAARGLEWIGNKISKFIEWMKSMLPQAQLKVKYLNELKKLNLYEKQVESLRVADMKTQEKIKMEIDTLHDLSRKFLPLYASEAKRIKTLYIKCDNIIKQKKRCEPVAIVIHGPPGAGKSITTNFLAKMITNDSDIYSLPPDPKYFDGYDQQSVVIMDDIMQNPAGDDMTLFCQMVSSVTFIPPMADLPDKGKAFDSRFVLCSTNHSLLTPPTITSLPAMNRRFFLDLDIIVHDNFKDPQGKLNVAAAFRPCDVDNRIGNARCCPFVCGKAVSFKDRNSCNKYSLAQVYNIMIEEDRRRRQVVDVMTAIFQGPIDMKNPPPPAITDLLQSVRTPEVIKYCEGNRWIIPAECKIEKELNLANTIITIIANVIGMARIIYVIYKLFCTLQGPYSGEPKPKTKIPERRVVTQGPEEEFGMSLIKHNSCVITTENGKFTGLGVYDRFVVVPTHADPGKEIQVDGITTKVIDSYDLYNKNGIKLEITVLKLDRNEKFRDIRRYIPNNEDDYPNCNLALLANQPEPTIINVGDVVSYGNILLSGNQTARMLKYSYPTKSGYCGGVLYKIGQVLGIHVGGNGRDGFSAMLLRSYFTDVQGQITLSKKTSECNLPSIHTPCKTKLQPSVFYDVFPGSKEPAVLSEKDARLQVDFNEALFSKYKGNTDCSINDHIRIASSHYAAQLITLDIDPKPITLEDSVFGTDGLEALDLNTSAGFPYIAMGVKKRDLINNKTKDISKLKEAIDKYGVDLPMVTFLKDELRKHEKVIKGKTRVIEASSVNDTLLFRTTFGNLFSKFHLNPGIVTGSAVGCDPEVFWSKIPAMLDDKCIMAFDYTNYDGSIHPIWFEALKQVLVDLSFNPTLIDRLCKSKHIFKNTYYEVEGGVPSGCSGTSIFNTMINNIIIRTLVLDAYKNIDLDKLKIIAYGDDVIFSYIHELDMEAIAIEGVKYGLTITPADKSNTFVKLDYSNVTFLKRGFKQDEKYNFLIHPTFPEDEIFESIRWTKKPSQMHEHVLSLCHLMWHNGRDAYKKFVEKIRSVSAGRALYIPPYDLLLHEWYEKF", "length": 2150, "reference_go_mf": ["GO:0005524", "GO:0015267", "GO:0004197", "GO:0017111", "GO:0003723", "GO:0003724", "GO:0003968", "GO:0005198", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_478_1ctn_assembly1", "enzyme_name": "chitinase (GH18, Class II)", "ec": ["3.2.1.14"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P07254", "alignment_score": 1058.0, "observed_coverage": 1.0, "aligned_identity": 0.9888475836431226, "canonical_span": [23, 561], "sequence": "MRKFNKPLLALLIGSTLCSAAQAAAPGKPTIAWGNTKFAIVEVDQAATAYNNLVKVKNAADVSVSWNLWNGDAGTTAKILLNGKEAWSGPSTGSSGTANFKVNKGGRYQMQVALCNADGCTASDATEIVVADTDGSHLAPLKEPLLEKNKPYKQNSGKVVGSYFVEWGVYGRNFTVDKIPAQNLTHLLYGFIPICGGNGINDSLKEIEGSFQALQRSCQGREDFKVSIHDPFAALQKAQKGVTAWDDPYKGNFGQLMALKQAHPDLKILPSIGGWTLSDPFFFMGDKVKRDRFVGSVKEFLQTWKFFDGVDIDWEFPGGKGANPNLGSPQDGETYVLLMKELRAMLDQLSAETGRKYELTSAISAGKDKIDKVAYNVAQNSMDHIFLMSYDFYGPFDLKNLGHQTALNAPAWKPDTAYTTVNGVNALLAQGVKPGKVVVGTAMYGRGWTGVNGYQNNIPFTGTATGPVKGTWKNGIVDYRQIAGQFMSGEWQYTYDATAEAPYVFKPSTGDLITFDDARSVQAKGKYVLDKQLGGLFSWEIDADNGDILNSMNASLGNSAGVQ", "length": 563, "reference_go_mf": ["GO:0008061", "GO:0008843"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_c64e025be5a016a2ba1d"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_479_1cwy_assembly1", "enzyme_name": "4-alpha-glucanotransferase", "ec": ["2.4.1.25"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "O87172", "alignment_score": 1000.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 500], "sequence": "MELPRAFGLLLHPTSLPGPYGVGVLGREARDFLRFLKEAGGRYWQVLPLGPTGYGDSPYQSFSAFAGNPYLIDLRPLAERGYVRLEDPGFPQGRVDYGLLYAWKWPALKEAFRGFKEKASPEEREAFAAFREREAWWLEDYALFMALKGAHGGLPWNRWPLPLRKREEKALREAKSALAEEVAFHAFTQWLFFRQWGALKAEAEALGIRIIGDMPIFVAEDSAEVWAHPEWFHLDEEGRPTVVAGVPPDYFSETGQRWGNPLYRWDVLEREGFSFWIRRLEKALELFHLVRIDHFRGFEAYWEIPASCPTAVEGRWVKAPGEKLFQKIQEVFGEVPVLAEDLGVITPEVEALRDRFGLPGMKVLQFAFDDGMENPFLPHNYPAHGRVVVYTGTHDNDTTLGWYRTATPHEKAFMARYLADWGITFREEEEVPWALMHLGMKSVARLAVYPVQDVLALGSEARMNYPGRPSGNWAWRLLPGELSPEHGARLRAMAEATERL", "length": 500, "reference_go_mf": ["GO:0004134"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_90c4398d77ed9e01c7b5"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_47_1ytw_assembly1", "enzyme_name": "protein-tyrosine-phosphatase non-receptor class", "ec": ["3.1.3.48"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P15273", "alignment_score": 563.0, "observed_coverage": 1.0, "aligned_identity": 0.9964664310954063, "canonical_span": [185, 468], "sequence": "MNLSLSDLHRQVSRLVQQESGDCTGKLRGNVAANKETTFQGLTIASGARESEKVFAQTVLSHVANIVLTQEDTAKLLQSTVKHNLNNYELRSVGNGNSVLVSLRSDQMTLQDAKVLLEAALRQESGARGHVSSHSHSVLHAPGTPVREGLRSHLDPRTPPLPPRERPHTSGHHGAGEARATAPSTVSPYGPEARAELSSRLTTLRNTLAPATNDPRYLQACGGEKLNRFRDIQCCRQTAVRADLNANYIQVGNTRTIACQYPLQSQLESHFRMLAENRTPVLAVLASSSEIANQRFGMPDYFRQSGTYGSITVESKMTQQVGLGDGIMADMYTLTIREAGQKTISVPVVHVGNWPDQTAVSSEVTKALASLVDQTAETKRNMYESKGSSAVADDSKLRPVIHCRAGVGRTAQLIGAMCMNDSRNSQLSVEDMVSQMRVQRNGIMVQKDEQLDVLIKLAEGQGRPLLNS", "length": 468, "reference_go_mf": ["GO:0004725"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_8164bc5aafe8423850db"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_480_1czf_assembly1", "enzyme_name": "polygalacturonase", "ec": ["3.2.1.15"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P26214", "alignment_score": 670.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [27, 362], "sequence": "MHSFASLLAYGLVAGATFASASPIEARDSCTFTTAAAAKAGKAKCSTITLNNIEVPAGTTLDLTGLTSGTKVIFEGTTTFQYEEWAGPLISMSGEHITVTGASGHLINCDGARWWDGKGTSGKKKPKFFYAHGLDSSSITGLNIKNTPLMAFSVQANDITFTDVTINNADGDTQGGHNTDAFDVGNSVGVNIIKPWVHNQDDCLAVNSGENIWFTGGTCIGGHGLSIGSVGDRSNNVVKNVTIEHSTVSNSENAVRIKTISGATGSVSEITYSNIVMSGISDYGVVIQQDYEDGKPTGKPTNGVTIQDVKLESVTGSVDSGATEIYLLCGSGSCSDWTWDDVKVTGGKKSTACKNFPSVASC", "length": 362, "reference_go_mf": ["GO:0047911", "GO:0004650"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_08ffa70e8c8dcfba24ca"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_481_1d2r_assembly1", "enzyme_name": "tryptophan---tRNA ligase", "ec": ["6.1.1.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00953", "alignment_score": 637.0, "observed_coverage": 1.0, "aligned_identity": 0.9846625766871165, "canonical_span": [0, 326], "sequence": "MKTIFSGIQPSGVITIGNYIGALRQFVELQHEYNCYFCIVDQHAITVWQDPHELRQNIRRLAAKYLAVGIDPTQATLFIQSEVPAHAQAAWMLQCIVYIGELERMTQFKEKSAGKEAVSAGLLTYPPLMAADILLYNTDIVPVGEDQKQHIELTRDLAERFNKRYGELFTIPEARIPKVGARIMSLVDPTKKMSKSDPNPKAYITLLDDAKTIEKKIKSAVTDSEGTIRYDKEAKPGISNLLNIYSTLSGQSIEELERQYEGKGYGVFKADLAQVVIETLRPIQERYHHWMESEELDRVLDEGAEKANRVASEMVRKMEQAMGLGRRR", "length": 328, "reference_go_mf": ["GO:0005524", "GO:0004830"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_00a353ff7926ffd2f84a"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_482_1d7r_assembly1", "enzyme_name": "2,2-dialkylglycine decarboxylase (pyruvate)", "ec": ["4.1.1.64"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P16932", "alignment_score": 862.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [2, 433], "sequence": "MSLNDDATFWRNARQHLVRYGGTFEPMIIERAKGSFVYDADGRAILDFTSGQMSAVLGHCHPEIVSVIGEYAGKLDHLFSGMLSRPVVDLATRLANITPPGLDRALLLSTGAESNEAAIRMAKLVTGKYEIVGFAQSWHGMTGAAASATYSAGRKGVGPAAVGSFAIPAPFTYRPRFERNGAYDYLAELDYAFDLIDRQSSGNLAAFIAEPILSSGGIIELPDGYMAALKRKCEARGMLLILDEAQTGVGRTGTMFACQRDGVTPDILTLSKTLGAGLPLAAIVTSAAIEERAHELGYLFYTTHVSDPLPAAVGLRVLDVVQRDGLVARANVMGDRLRRGLLDLMERFDCIGDVRGRGLLLGVEIVKDRRTKEPADGLGAKITRECMNLGLSMNIVQLPGMGGVFRIAPPLTVSEDEIDLGLSLLGQAIERAL", "length": 433, "reference_go_mf": ["GO:0047432", "GO:0030170"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_f39838735768dd088a30"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_483_4hpn_assembly1", "enzyme_name": "galactarolactone cycloisomerase", "ec": ["5.5.1.27"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "A9CEQ8", "alignment_score": 756.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 378], "sequence": "MKITAVRTHLLEHRLDTPFESASMRFDRRAHVLVEIECDDGTVGWGECLGPARPNAAVVQAYSGWLIGQDPRQTEKIWAVLYNALRDQGQRGLSLTALSGIDIALWDIKGKHYGASISMLLGGRWRESVRAYATGSFKRDNVDRVSDNASEMAERRAEGFHACKIKIGFGVEEDLRVIAAVREAIGPDMRLMIDANHGYTVTEAITLGDRAAGFGIDWFEEPVVPEQLDAYARVRAGQPIPVAGGETWHGRYGMWQALSAGAVDILQPDLCGCGGFSEIQKIATLATLHGVRIVPHVWGTGVQIAAALQFMAAMTPDPVRVNPIEPIMEFDRTHNPFRQAVLREPLEAVNGVVTIPDGPGLGIEINRDALTEFRMPDP", "length": 378, "reference_go_mf": ["GO:0016836", "GO:0016853", "GO:0000287"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_2682e568936afa89aa18"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_484_1d8d_assembly1", "enzyme_name": "protein farnesyltransferase", "ec": ["2.5.1.58"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q04631", "alignment_score": 646.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [54, 377], "sequence": "MAATEGVGESAPGGEPGQPEQPPPPPPPPPAQQPQEEEMAAEAGEAAASPMDDGFLSLDSPTYVLYRDRAEWADIDPVPQNDGPSPVVQIIYSEKFRDVYDYFRAVLQRDERSERAFKLTRDAIELNAANYTVWHFRRVLLRSLQKDLQEEMNYIIAIIEEQPKNYQVWHHRRVLVEWLKDPSQELEFIADILNQDAKNYHAWQHRQWVIQEFRLWDNELQYVDQLLKEDVRNNSVWNQRHFVISNTTGYSDRAVLEREVQYTLEMIKLVPHNESAWNYLKGILQDRGLSRYPNLLNQLLDLQPSHSSPYLIAFLVDIYEDMLENQCDNKEDILNKALELCEILAKEKDTIRKEYWRYIGRSLQSKHSRESDIPASV", "length": 377, "reference_go_mf": ["GO:0010698", "GO:0043014", "GO:0004662", "GO:0019899", "GO:0008017", "GO:0060090", "GO:0004660", "GO:0004661", "GO:0004663", "GO:0030971"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_83d6a1e87bae79772936"}, "alternative_alignments": [{"accession": "Q02293", "alignment_score": 9.0, "observed_coverage": 0.018575851393188854, "aligned_identity": 0.8333333333333334, "canonical_span": [69, 75], "length": 437, "reference_go_mf": ["GO:0010698", "GO:0019899", "GO:0004311", "GO:0004660", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, {"accession": "P01116", "alignment_score": 7.0, "observed_coverage": 0.015479876160990712, "aligned_identity": 0.8, "canonical_span": [24, 29], "length": 189, "reference_go_mf": ["GO:0003925", "GO:0019003", "GO:0019002", "GO:0005525", "GO:0003924", "GO:0042802", "GO:0030275", "GO:0044877"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}, {"chain": "B", "status": "assigned", "selected": {"accession": "Q02293", "alignment_score": 814.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [16, 423], "sequence": "MASSSSFTYYCPPSSSPVWSEPLYSLRPEHARERLQDDSVETVTSIEQAKVEEKIQEVFSSYKFNHLVPRLVLQREKHFHYLKRGLRQLTDAYECLDASRPWLCYWILHSLELLDEPIPQIVATDVCQFLELCQSPDGGFGGGPGQYPHLAPTYAAVNALCIIGTEEAYNVINREKLLQYLYSLKQPDGSFLMHVGGEVDVRSAYCAASVASLTNIITPDLFEGTAEWIARCQNWEGGIGGVPGMEAHGGYTFCGLAALVILKKERSLNLKSLLQWVTSRQMRFEGGFQGRCNKLVDGCYSFWQAGLLPLLHRALHAQGDPALSMSHWMFHQQALQEYILMCCQCPAGGLLDKPGKSRDFYHTCYCLSGLSIAQHFGSGAMLHDVVMGVPENVLQPTHPVYNIGPDKVIQATTHFLQKPVPGFEECEDAVTSDPATD", "length": 437, "reference_go_mf": ["GO:0010698", "GO:0019899", "GO:0004311", "GO:0004660", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_0eb377a79304da87e327"}, "alternative_alignments": [{"accession": "Q04631", "alignment_score": 9.0, "observed_coverage": 0.014742014742014743, "aligned_identity": 0.8333333333333334, "canonical_span": [103, 109], "length": 377, "reference_go_mf": ["GO:0010698", "GO:0043014", "GO:0004662", "GO:0019899", "GO:0008017", "GO:0060090", "GO:0004660", "GO:0004661", "GO:0004663", "GO:0030971"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, {"accession": "P01116", "alignment_score": 7.0, "observed_coverage": 0.012285012285012284, "aligned_identity": 0.8, "canonical_span": [9, 14], "length": 189, "reference_go_mf": ["GO:0003925", "GO:0019003", "GO:0019002", "GO:0005525", "GO:0003924", "GO:0042802", "GO:0030275", "GO:0044877"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_486_1d8h_assembly1", "enzyme_name": "polynucleotide 5'-phosphatase", "ec": ["3.1.3.33"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "O13297", "alignment_score": 554.5, "observed_coverage": 0.9930555555555556, "aligned_identity": 1.0, "canonical_span": [240, 539], "sequence": "MSYTDNPPQTKRALSLDDLVNHDENEKVKLQKLSEAANGSRPFAENLESDINQTETGQAAPIDNYKESTGHGSHSQKPKSRKSSNDDEETDTDDEMGASGEINFDSEMDFDYDKQHRNLLSNGSPPMNDGSDANAKLEKPSDDSIHQNSKSDEEQRIPKQGNEGNIASNYITQVPLQKQKQTEKKIAGNAVGSVVKKEEEANAAVDNIFEEKATLQSKKNNIKRDLEVLNEISASSKPSKYRNVPIWAQKWKPTIKALQSINVKDLKIDPSFLNIIPDDDLTKSVQDWVYATIYSIAPELRSFIELEMKFGVIIDAKGPDRVNPPVSSQCVFTELDAHLTPNIDASLFKELSKYIRGISEVTENTGKFSIIESQTRDSVYRVGLSTQRPRFLRMSTDIKTGRVGQFIEKRHVAQLLLYSPKDSYDVKISLNLELPVPDNDPPEKYKSQSPISERTKDRVSYIHNDSCTRIDITKVENHNQNSKSRQSETTHEVELEINTPALLNAFDNITNDSKEYASLIRTFLNNGTIIRRKLSSLSYEIFEGSKKVM", "length": 549, "reference_go_mf": ["GO:0140818", "GO:0004651"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_faf9e53b574f9c2ee405"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_487_1db3_assembly1", "enzyme_name": "GDP-mannose 4,6-dehydratase", "ec": ["4.2.1.47"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0AC88", "alignment_score": 648.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 358], "sequence": "MSKVALITGVTGQDGSYLAEFLLEKGYEVHGIKRRASSFNTERVDHIYQDPHTCNPKFHLHYGDLSDTSNLTRILREVQPDEVYNLGAMSHVAVSFESPEYTADVDAMGTLRLLEAIRFLGLEKKTRFYQASTSELYGLVQEIPQKETTPFYPRSPYAVAKLYAYWITVNYRESYGMYACNGILFNHESPRRGETFVTRKITRAIANIAQGLESCLYLGNMDSLRDWGHAKDYVKMQWMMLQQEQPEDFVIATGVQYSVRQFVEMAAAQLGIKLRFEGTGVEEKGIVVSVTGHDAPGVKPGDVIIAVDPRYFRPAEVETLLGDPTKAHEKLGWKPEITLREMVSEMVANDLEAAKKHSLLKSHGYDVAIALES", "length": 373, "reference_go_mf": ["GO:0008446", "GO:0070401", "GO:0042803"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_d1220270c50d6dc7e9d5"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_488_1de6_assembly1", "enzyme_name": "L-rhamnose isomerase", "ec": ["5.3.1.14"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P32170", "alignment_score": 829.0, "observed_coverage": 1.0, "aligned_identity": 0.9975961538461539, "canonical_span": [2, 418], "sequence": "MTTQLEQAWELAKQRFAAVGIDVEEALRQLDRLPVSMHCWQGDDVSGFENPEGSLTGGIQATGNYPGKARNASELRADLEQAMRLIPGPKRLNLHAIYLESDTPVSRDQIKPEHFKNWVEWAKANQLGLDFNPSCFSHPLSADGFTLSHADDSIRQFWIDHCKASRRVSAYFGEQLGTPSVMNIWIPDGMKDITVDRLAPRQRLLAALDEVISEKLNPAHHIDAVESKLFGIGAESYTVGSNEFYMGYATSRQTALCLDAGHFHPTEVISDKISAAMLYVPQLLLHVSRPVRWDSDHVVLLDDETQAIASEIVRHDLFDRVHIGLDFFDASINRIAAWVIGTRNMKKALLRALLEPTAELRKLEAAGDYTARLALLEEQKSLPWQAVWEMYCQRHDTPAGSEWLESVRAYEKEILSRRG", "length": 419, "reference_go_mf": ["GO:0042802", "GO:0008740", "GO:0030145", "GO:0033296", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_5c60b26ade5733c2d22e"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_48_1bzy_assembly1", "enzyme_name": "hypoxanthine phosphoribosyltransferase", "ec": ["2.4.2.8"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00492", "alignment_score": 428.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [4, 218], "sequence": "MATRSPGVVISDDEPGYDLDLFCIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRDLNHVCVISETGKAKYKA", "length": 218, "reference_go_mf": ["GO:0052657", "GO:0004422", "GO:0042802", "GO:0000287"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_819c9375ca8203a769c0"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_493_1dj0_assembly1", "enzyme_name": "tRNA pseudouridine38-40 synthase", "ec": ["5.4.99.12"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P07649", "alignment_score": 528.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [6, 270], "sequence": "MSDQQQPPVYKIALGIEYDGSKYYGWQRQNEVRSVQEKLEKALSQVANEPITVFCAGRTDAGVHGTGQVVHFETTALRKDAAWTLGVNANLPGDIAVRWVKTVPDDFHARFSATARRYRYIIYNHRLRPAVLSKGVTHFYEPLDAERMHRAAQCLLGENDFTSFRAVQCQSRTPWRNVMHINVTRHGPYVVVDIKANAFVHHMVRNIVGSLMEVGAHNQPESWIAELLAAKDRTLAAATAKAEGLYLVAVDYPDRYDLPKPPMGPLFLAD", "length": 270, "reference_go_mf": ["GO:0042803", "GO:0000049", "GO:0106029", "GO:0160147"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_6d2536c8108add339770"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_494_1dio_assembly1", "enzyme_name": "propanediol dehydratase", "ec": ["4.2.1.28"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q59470", "alignment_score": 1102.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 551], "sequence": "MRSKRFEALAKRPVNQDGFVKEWIEEGFIAMESPNDPKPSIKIVNGAVTELDGKPVSDFDLIDHFIARYGINLNRAEEVMAMDSVKLANMLCDPNVKRSEIVPLTTAMTPAKIVEVVSHMNVVEMMMAMQKMRARRTPSQQAHVTNVKDNPVQIAADAAEGAWRGFDEQETTVAVARYAPFNAIALLVGSQVGRPGVLTQCSLEEATELKLGMLGHTCYAETISVYGTEPVFTDGDDTPWSKGFLASSYASRGLKMRFTSGSGSEVQMGYAEGKSMLYLEARCIYITKAAGVQGLQNGSVSCIGVPSAVPSGIRAVLAENLICSSLDLECASSNDQTFTHSDMRRTARLLMQFLPGTDFISSGYSAVPNYDNMFAGSNEDAEDFDDYNVIQRDLKVDGGLRPVREEDVIAIRNKAARALQAVFAGMGLPPITDEEVEAATYAHGSKDMPERNIVEDIKFAQEIINKNRNGLEVVKALAQGGFTDVAQDMLNIQKAKLTGDYLHTSAIIVGDGQVLSAVNDVNDYAGPATGYRLQGERWEEIKNIPGALDPNEID", "length": 554, "reference_go_mf": ["GO:0031419", "GO:0050215"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_bdd6e950c847b4c0ee7f"}, "alternative_alignments": [{"accession": "Q59472", "alignment_score": 11.0, "observed_coverage": 0.018148820326678767, "aligned_identity": 0.7, "canonical_span": [26, 36], "length": 173, "reference_go_mf": ["GO:0050215"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, {"accession": "Q59471", "alignment_score": 8.0, "observed_coverage": 0.007259528130671506, "aligned_identity": 1.0, "canonical_span": [23, 27], "length": 224, "reference_go_mf": ["GO:0050215"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_495_1dmu_assembly1", "enzyme_name": "type II site-specific deoxyribonuclease,  BgII", "ec": ["3.1.21.4"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "O68557", "alignment_score": 598.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 299], "sequence": "MYNLHREKIFMSYNQNKQYLEDNPEIQEKIELYGLNLLNEVISDNEEEIRADYNEANFLHPFWMNYPPLDRGKMPKGDQIPWIEVGEKAVGSKLTRLVSQREDITVREIGLPTGPDERYLLTSPTIYSLTNGFTDSIMMFVDIKSVGPRDSDYDLVLSPNQVSGNGDWAQLEGGIQNNQQTIQGPRSSQIFLPTIPPLYILSDGTIAPVVHLFIKPIYAMRSLTKGDTGQSLYKIKLASVPNGLGLFCNPGYAFDSAYKFLFRPGKDDRTKSLLQKRVRVDLRVLDKIGPRVMTIDMDK", "length": 299, "reference_go_mf": ["GO:0009036"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_2c8b925eefb853c6d45e"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_496_1djl_assembly1", "enzyme_name": "NAD(P)+ transhydrogenase (Re/Si-specific)", "ec": ["1.6.1.2"], "controls": [{"chain": "A", "status": "reference_overlength", "selected": {"accession": "Q13423", "alignment_score": 364.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [901, 1083], "sequence": "MANLLKTVVTGCSCPLLSNLGSCKGLRVKKDFLRTFYTHQELWCKAPVKPGIPYKQLTVGVPKEIFQNEKRVALSPAGVQNLVKQGFNVVVESGAGEASKFSDDHYRVAGAQIQGAKEVLASDLVVKVRAPMVNPTLGVHEADLLKTSGTLISFIYPAQNPELLNKLSQRKTTVLAMDQVPRVTIAQGYDALSSMANIAGYKAVVLAANHFGRFFTGQITAAGKVPPAKILIVGGGVAGLASAGAAKSMGAIVRGFDTRAAALEQFKSLGAEPLEVDLKESGEGQGGYAKEMSKEFIEAEMKLFAQQCKEVDILISTALIPGKKAPVLFNKEMIESMKEGSVVVDLAAEAGGNFETTKPGELYIHKGITHIGYTDLPSRMATQASTLYSNNITKLLKAISPDKDNFYFDVKDDFDFGTMGHVIRGTVVMKDGKVIFPAPTPKNIPQGAPVKQKTVAELEAEKAATITPFRKTMSTASAYTAGLTGILGLGIAAPNLAFSQMVTTFGLAGIVGYHTVWGVTPALHSPLMSVTNAISGLTAVGGLALMGGHLYPSTTSQGLAALAAFISSVNIAGGFLVTQRMLDMFKRPTDPPEYNYLYLLPAGTFVGGYLAALYSGYNIEQIMYLGSGLCCVGALAGLSTQGTARLGNALGMIGVAGGLAATLGVLKPGPELLAQMSGAMALGGTIGLTIAKRIQISDLPQLVAAFHSLVGLAAVLTCIAEYIIEYPHFATDAAANLTKIVAYLGTYIGGVTFSGSLIAYGKLQGLLKSAPLLLPGRHLLNAGLLAASVGGIIPFMVDPSFTTGITCLGSVSALSAVMGVTLTAAIGGADMPVVITVLNSYSGWALCAEGFLLNNNLLTIVGALIGSSGAILSYIMCVAMNRSLANVILGGYGTTSTAGGKPMEISGTHTEINLDNAIDMIREANSIIITPGYGLCAAKAQYPIADLVKMLTEQGKKVRFGIHPVAGRMPGQLNVLLAEAGVPYDIVLEMDEINHDFPDTDLVLVIGANDTVNSAAQEDPNSIIAGMPVLEVWKSKQVIVMKRSLGVGYAAVDNPIFYKPNTAMLLGDAKKTCDALQAKVRESYQK", "length": 1086, "reference_go_mf": ["GO:0051287", "GO:0003957", "GO:0050661", "GO:0008750"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_497_1ycf_assembly1", "enzyme_name": "nitric-oxide reductase (FMN)", "ec": ["1.7.-.-"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q9FDN7", "alignment_score": 796.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 399], "sequence": "MSQPVAITDGIYWVGAVDWNIRYFHGPAFSTHRGTTYNAYLIVDDKTALVDTVYEPFKEELIAKLKQIKDPVKLDYLVVNHTESDHAGAFPAIMELCPDAHVLCTQRAFDSLKAHYSHIDFNYTIVKTGTSVSLGKRSLTFIEAPMLHWPDSMFTYVPEEALLLPNDAFGQHIATSVRFDDQVDAGLIMDEAAKYYANILMPFSNLITKKLDEIQKINLAIKTIAPSHGIIWRKDPGRIIEAYARWAEGQGKAKAVIAYDTMWLSTEKMAHALMDGLVAGGCEVKLFKLSVSDRNDVIKEILDARAVLVGSPTINNDILPVVSPLLDDLVGLRPKNKVGLAFGAYGWGGGAQKILEERLKAAKIELIAEPGPTVQWVPRGEDLQRCYELGRKIAARIAD", "length": 399, "reference_go_mf": ["GO:0009055", "GO:0010181", "GO:0046872", "GO:0016651"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_407d709e3d31eb2dc32e"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_498_2hgs_assembly1", "enzyme_name": "glutathione synthase (eukaryotic)", "ec": ["6.3.2.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P48637", "alignment_score": 944.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [2, 474], "sequence": "MATNWGSLLQDKQQLEELARQAVDRALAEGVLLRTSQEPTSSEVVSYAPFTLFPSLVPSALLEQAYAVQMDFNLLVDAVSQNAAFLEQTLSSTIKQDDFTARLFDIHKQVLKEGIAQTVFLGLNRSDYMFQRSADGSPALKQIEINTISASFGGLASRTPAVHRHVLSVLSKTKEAGKILSNNPSKGLALGIAKAWELYGSPNALVLLIAQEKERNIFDQRAIENELLARNIHVIRRTFEDISEKGSLDQDRRLFVDGQEIAVVYFRDGYMPRQYSLQNWEARLLLERSHAAKCPDIATQLAGTKKVQQELSRPGMLEMLLPGQPEAVARLRATFAGLYSLDVGEEGDQAIAEALAAPSRFVLKPQREGGGNNLYGEEMVQALKQLKDSEERASYILMEKIEPEPFENCLLRPGSPARVVQCISELGIFGVYVRQEKTLVMNKHVGHLLRTKAIEHADGGVAAGVAVLDNPYPV", "length": 474, "reference_go_mf": ["GO:0005524", "GO:0043295", "GO:0004363", "GO:0042802", "GO:0000287", "GO:0042803"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_8abef2cc2459808a5daa"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_499_1pjh_assembly1", "enzyme_name": "3,2-trans-enoyl-CoA isomerase (peroxisomal)", "ec": ["5.3.3.8"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q05871", "alignment_score": 506.0, "observed_coverage": 1.0, "aligned_identity": 0.9961389961389961, "canonical_span": [4, 270], "sequence": "MSQEIRQNEKISYRIEGPFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGRFFSSGADFKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLSAALVALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYDIMCENGFISKNFNMPSSNAEAFNAKVLEELREKVKGLYLPSCLGMKKLLKSNHIDAFNKANSVEVNESLKYWVDGEPLKRFRQLGSKQRKHRL", "length": 280, "reference_go_mf": ["GO:0004165"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_10f52d694f19898cba49"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_4_1nia_assembly1", "enzyme_name": "nitrite reductase (copper type)", "ec": ["1.7.2.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P25006", "alignment_score": 666.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [45, 378], "sequence": "MTEQLQMTRRTMLAGAALAGAVAPLLHTAQAHAAGAAAAAGAAPVDISTLPRVKVDLVKPPFVHAHDQVAKTGPRVVEFTMTIEEKKLVIDREGTEIHAMTFNGSVPGPLMVVHENDYVELRLINPDTNTLLHNIDFHAATGALGGGALTQVNPGEETTLRFKATKPGVFVYHCAPEGMVPWHVTSGMNGAIMVLPRDGLKDEKGQPLTYDKIYYVGEQDFYVPKDEAGNYKKYETPGEAYEDAVKAMRTLTPTHIVFNGAVGALTGDHALTAAVGERVLVVHSQANRDTRPHLIGGHGDYVWATGKFRNPPDLDQETWLIPGGTAGAAFYTFRQPGVYAYVNHNLIEAFELGAAGHFKVTGEWNDDLMTSVVKPASM", "length": 378, "reference_go_mf": ["GO:0005507", "GO:0050421"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_624475dc42b8512304de"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P25006", "alignment_score": 666.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [45, 378], "sequence": "MTEQLQMTRRTMLAGAALAGAVAPLLHTAQAHAAGAAAAAGAAPVDISTLPRVKVDLVKPPFVHAHDQVAKTGPRVVEFTMTIEEKKLVIDREGTEIHAMTFNGSVPGPLMVVHENDYVELRLINPDTNTLLHNIDFHAATGALGGGALTQVNPGEETTLRFKATKPGVFVYHCAPEGMVPWHVTSGMNGAIMVLPRDGLKDEKGQPLTYDKIYYVGEQDFYVPKDEAGNYKKYETPGEAYEDAVKAMRTLTPTHIVFNGAVGALTGDHALTAAVGERVLVVHSQANRDTRPHLIGGHGDYVWATGKFRNPPDLDQETWLIPGGTAGAAFYTFRQPGVYAYVNHNLIEAFELGAAGHFKVTGEWNDDLMTSVVKPASM", "length": 378, "reference_go_mf": ["GO:0005507", "GO:0050421"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_624475dc42b8512304de"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_500_1e3i_assembly1", "enzyme_name": "alcohol dehydrogenase (class II)", "ec": ["1.1.1.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q9QYY9", "alignment_score": 746.0, "observed_coverage": 1.0, "aligned_identity": 0.9946808510638298, "canonical_span": [1, 377], "sequence": "MGTQGKVIKCKAAIAWKTGSPLCIEEIEVSPPKACEVRIQVIATCVCPTDINATDPKKKALFPVVLGHECAGIVESVGPGVTNFKPGDKVIPFFAPQCKRCKLCLSPLTNLCGKLRNFKYPTIDQELMEDRTSRFTCKGRSIYHFMGVSSFSQYTVVSEANLARVDDEANLERVCLIGCGFSSGYGAAINTAKVTPSSTCAVFGLGCVGLSAIIGCKIAGASRIIAIDINGEKFPKAKALGATDCLNPRELDKPVQDVITELTAGGVDYSLDCAGTAQTLKAAVDCTVLGWGSCTVVGAKVDKMTIPTVDVILGRSINGTFFGGWKSVDSVPNLVSDYKNKKFDLDLLVTHALPFESINDAIDLMKEGKSIRTILTF", "length": 377, "reference_go_mf": ["GO:0004022", "GO:0004032", "GO:0005503", "GO:0004745", "GO:0018479", "GO:0050061", "GO:0051287", "GO:0050136", "GO:0003960", "GO:0019841", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_ca7b744710c8003de1e8"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_502_3es7_assembly2", "enzyme_name": "galactarate dehydratase (D-threo-forming)", "ec": ["4.2.1.158"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q8EMJ9", "alignment_score": 774.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 387], "sequence": "MKITDLELHAVGIPRHTGFVNKHVIVKIHTDEGLTGIGEMSDFSHLPLYSVDLHDLKQGLLSILLGQNPFDLMKINKELTDNFPETMYYYEKGSFIRNGIDNALHDLCAKYLDISVSDFLGGRVKEKIKVCYPIFRHRFSEEVESNLDVVRQKLEQGFDVFRLYVGKNLDADEEFLSRVKEEFGSRVRIKSYDFSHLLNWKDAHRAIKRLTKYDLGLEMIESPAPRNDFDGLYQLRLKTDYPISEHVWSFKQQQEMIKKDAIDIFNISPVFIGGLTSAKKAAYAAEVASKDVVLGTTQELSVGTAAMAHLGCSLTNINHTSDPTGPELYVGDVVKNRVTYKDGYLYAPDRSVKGLGIELDESLLAKYQVPDLSWDNVTVHQLQDRTADTKS", "length": 391, "reference_go_mf": ["GO:0003824"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_c9ea71c8320405371e79"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_504_1qhf_assembly1", "enzyme_name": "phosphoglycerate mutase (2,3-diphosphoglycerate-dependent)", "ec": ["5.4.2.11"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00950", "alignment_score": 480.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 241], "sequence": "MPKLVLVRHGQSEWNEKNLFTGWVDVKLSAKGQQEAARAGELLKEKKVYPDVLYTSKLSRAIQTANIALEKADRLWIPVNRSWRLNERHYGDLQGKDKAETLKKFGEEKFNTYRRSFDVPPPPIDASSPFSQKGDERYKYVDPNVLPETESLALVIDRLLPYWQDVIAKDLLSGKTVMIAAHGNSLRGLVKHLEGISDADIAKLNIPTGIPLVFELDENLKPSKPSYYLDPEAAAAGAAAVANQGKK", "length": 247, "reference_go_mf": ["GO:0004619"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_e3bcca17b94fed656e50"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_506_1fnb_assembly1", "enzyme_name": "ferredoxin--NADP reductase", "ec": ["1.18.1.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00455", "alignment_score": 589.0, "observed_coverage": 1.0, "aligned_identity": 0.9966216216216216, "canonical_span": [73, 369], "sequence": "MTTAVTAAVSFPSTKTTSLSARSSSVISPDKISYKKVPLYYRNVSATGKMGPIRAQIASDVEAPPPAPAKVEKHSKKMEEGITVNKFKPKTPYVGRCLLNTKITGDDAPGETWHMVFSHEGEIPYREGQSVGVIPDGEDKNGKPHKLRLYSIASSALGDFGDAKSVSLCVKRLIYTNDAGETIKGVCSNFLCDLKPGAEVKLTGPVGKEMLMPKDPNATIIMLGTGTGIAPFRSFLWKMFFEKHDDYKFNGLAWLFLGVPTSSSLLYKEEFEKMKEKAPDNFRLDFAVSREQTNEKGEKMYIQTRMAQYAVELWEMLKKDNTYFYMCGLKGMEKGIDDIMVSLAAAEGIDWIEYKRQLKKAEQWNVEVY", "length": 369, "reference_go_mf": ["GO:0004324"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_fda73a017262a29e913b"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_507_1c17_assembly1", "enzyme_name": "H+-transporting two-sector ATPase (F-type, bacterial)", "ec": ["7.1.2.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P68699", "alignment_score": 158.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 79], "sequence": "MENLNMDLLYMAAAVMMGLAAIGAAIGIGILGGKFLEGAARQPDLIPLLRTQFFIVMGLVDAIPMIAVGLGLYVMFAVA", "length": 79, "reference_go_mf": ["GO:0046933", "GO:0046961"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_82c2a67efb6551d59bf1"}, "alternative_alignments": [{"accession": "P0AB98", "alignment_score": 8.0, "observed_coverage": 0.05063291139240506, "aligned_identity": 1.0, "canonical_span": [117, 121], "length": 271, "reference_go_mf": ["GO:0046933"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}, {"chain": "B", "status": "assigned", "selected": {"accession": "P0AB98", "alignment_score": 264.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [94, 265], "sequence": "MASENMTPQDYIGHHLNNLQLDLRTFSLVDPQNPPATFWTINIDSMFFSVVLGLLFLVLFRSVAKKATSGVPGKFQTAIELVIGFVNGSVKDMYHGKSKLIAPLALTIFVWVFLMNLMDLLPIDLLPYIAEHVLGLPALRVVPSADVNVTLSMALGVFILILFYSIKMKGIGGFTKELTLQPFNHWAFIPVNLILEGVSLLSKPVSLGLRLFGNMYAGELIFILIAGLLPWWSQWILNVPWAIFHILIITLQAFIFMVLTIVYLSMASEEH", "length": 271, "reference_go_mf": ["GO:0046933"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_82b25b211a464de4395d"}, "alternative_alignments": [{"accession": "P68699", "alignment_score": 8.0, "observed_coverage": 0.028169014084507043, "aligned_identity": 1.0, "canonical_span": [5, 9], "length": 79, "reference_go_mf": ["GO:0046933", "GO:0046961"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_508_1lws_assembly1", "enzyme_name": "H+-transporting two-sector ATPase (V-type)", "ec": ["7.1.2.2"], "controls": [{"chain": "A", "status": "reference_overlength", "selected": {"accession": "P17255", "alignment_score": 754.5, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [283, 737], "sequence": "MAGAIENARKEIKRISLEDHAESEYGAIYSVSGPVVIAENMIGCAMYELVKVGHDNLVGEVIRIDGDKATIQVYEETAGLTVGDPVLRTGKPLSVELGPGLMETIYDGIQRPLKAIKEESQSIYIPRGIDTPALDRTIKWQFTPGKFQVGDHISGGDIYGSVFENSLISSHKILLPPRSRGTITWIAPAGEYTLDEKILEVEFDGKKSDFTLYHTWPVRVPRPVTEKLSADYPLLTGQRVLDALFPCVQGGTTCIPGAFGCGKTVISQSLSKYSNSDAIIYVGCFAKGTNVLMADGSIECIENIEVGNKVMGKDGRPREVIKLPRGRETMYSVVQKSQHRAHKSDSSREVPELLKFTCNATHELVVRTPRSVRRLSRTIKGVEYFEVITFEMGQKKAPDGRIVELVKEVSKSYPISEGPERANELVESYRKASNKAYFEWTIEARDLSLLGSHVRKATYQTYAPILYENDHFFDYMQKSKFHLTIEGPKVLAYLLGLWIGDGLSDRATFSVDSRDTSLMERVTEYAEKLNLCAEYKDRKEPQVAKTVNLYSKVVRGNGIRNNLNTENPLWDAIVGLGFLKDGVKNIPSFLSTDNIGTRETFLAGLIDSDGYVTDEHGIKATIKTIHTSVRDGLVSLARSLGLVVSVNAEPAKVDMNGTKHKISYAIYMSGGDVLLNVLSKCAGSKKFRPAPAAAFARECRGFYFELQELKEDDYYGITLSDDSDHQFLLANQVVVHNCGERGNEMAEVLMEFPELYTEMSGTKEPIMKRTTLVANTSNMPVAAREASIYTGITLAEYFRDQGKNVSMIADSSSRWAEALREISGRLGEMPADQGFPAYLGAKLASFYERAGKAVALGSPDRTGSVSIVAAVSPAGGDFSDPVTTATLGITQVFWGLDKKLAQRKHFPSINTSVSYSKYTNVLNKFYDSNYPEFPVLRDRMKEILSNAEELEQVVQLVGKSALSDSDKITLDVATLIKEDFLQQNGYSTYDAFCPIWKTFDMMRAFISYHDEAQKAVANGANWSKLADSTGDVKHAVSSSKFFEPSRGEKEVHGEFEKLLSTMQERFAESTD", "length": 1071, "reference_go_mf": ["GO:0005524", "GO:0003677", "GO:0004519", "GO:0003729", "GO:0046961"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_50_1dbt_assembly1", "enzyme_name": "orotidine-5'-phosphate decarboxylase", "ec": ["4.1.1.23"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P25971", "alignment_score": 474.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 237], "sequence": "MKNNLPIIALDFASAEETLAFLAPFQQEPLFVKVGMELFYQEGPSIVKQLKERNCELFLDLKLHDIPTTVNKAMKRLASLGVDLVNVHAAGGKKMMQAALEGLEEGTPAGKKRPSLIAVTQLTSTSEQIMKDELLIEKSLIDTVVHYSKQAEESGLDGVVCSVHEAKAIYQAVSPSFLTVTPGIRMSEDAANDQVRVATPAIAREKGSSAIVVGRSITKAEDPVKAYKAVRLEWEGIKS", "length": 239, "reference_go_mf": ["GO:0004590"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_422db3b3e63587065108"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P25971", "alignment_score": 468.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [2, 236], "sequence": "MKNNLPIIALDFASAEETLAFLAPFQQEPLFVKVGMELFYQEGPSIVKQLKERNCELFLDLKLHDIPTTVNKAMKRLASLGVDLVNVHAAGGKKMMQAALEGLEEGTPAGKKRPSLIAVTQLTSTSEQIMKDELLIEKSLIDTVVHYSKQAEESGLDGVVCSVHEAKAIYQAVSPSFLTVTPGIRMSEDAANDQVRVATPAIAREKGSSAIVVGRSITKAEDPVKAYKAVRLEWEGIKS", "length": 239, "reference_go_mf": ["GO:0004590"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_422db3b3e63587065108"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_510_1bix_assembly1", "enzyme_name": "8-oxoguanine DNA-glycosylase (ExoA family)", "ec": ["4.2.99.18"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P27695", "alignment_score": 550.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [43, 318], "sequence": "MPKRGKKGAVAEDGDELRTEPEAKKSKTAAKKNDKEAAGEGPALYEDPPDQKTSPSGKPATLKICSWNVDGLRAWIKKKGLDWVKEEAPDILCLQETKCSENKLPAELQELPGLSHQYWSAPSDKEGYSGVGLLSRQCPLKVSYGIGDEEHDQEGRVIVAEFDSFVLVTAYVPNAGRGLVRLEYRQRWDEAFRKFLKGLASRKPLVLCGDLNVAHEEIDLRNPKGNKKNAGFTPQERQGFGELLQAVPLADSFRHLYPNTPYAYTFWTYMMNARSKNVGWRLDYFLLSHSLLPALCDSKIRSKALGSDHCPITLYLAL", "length": 318, "reference_go_mf": ["GO:0008408", "GO:0008296", "GO:0031490", "GO:0052720", "GO:0003684", "GO:0033892", "GO:0003677", "GO:0004520", "GO:0140431", "GO:0003906", "GO:0008311", "GO:0008309", "GO:0003691", "GO:0004519", "GO:0046872", "GO:0016491", "GO:0090580", "GO:0004528", "GO:0008081", "GO:0003723", "GO:0004523", "GO:0003713", "GO:0003714", "GO:0004844"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_26609ead5948182ab7db"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_511_1nmw_assembly1", "enzyme_name": "peptidylprolyl isomerase (PpiC-type)", "ec": ["5.2.1.8"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q13526", "alignment_score": 228.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [49, 163], "sequence": "MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE", "length": 163, "reference_go_mf": ["GO:0008013", "GO:0016859", "GO:0003774", "GO:0032794", "GO:0031434", "GO:0003755", "GO:0051219", "GO:0050815", "GO:0050816", "GO:0048156", "GO:1990757"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_d8766228613d90eec8b5"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_512_1eej_assembly1", "enzyme_name": "protein disulfide-isomerase (DsbC)", "ec": ["5.3.4.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0AEG6", "alignment_score": 432.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [20, 236], "sequence": "MKKGFMLFTLLAAFSGFAQADDAAIQQTLAKMGIKSSDIQPAPVAGMKTVLTNSGVLYITDDGKHIIQGPMYDVSGTAPVNVTNKMLLKQLNALEKEMIVYKAPQEKHVITVFTDITCGYCHKLHEQMADYNALGITVRYLAFPRQGLDSDAEKEMKAIWCAKDKNKAFDDVMAGKSVAPASCDVDIADHYALGVQLGVSGTPAVVLSNGTLVPGYQPPKEMKEFLDEHQKMTSGK", "length": 236, "reference_go_mf": ["GO:0003756", "GO:0042803", "GO:0015035"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_dd74ea51edd5cf81631e"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_513_1gpr_assembly1", "enzyme_name": "protein-Npi-phosphohistidine---sugar phosphotransferase (type II)", "ec": ["2.7.1.191"], "controls": [{"chain": "A", "status": "missing_reference", "selected": null, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_514_1e2a_assembly1", "enzyme_name": "protein-Npi-phosphohistidine---sugar phosphotransferase (type III)", "ec": ["2.7.1.191"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P23532", "alignment_score": 204.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 102], "sequence": "MNREEMTLLGFEIVAYAGDARSKLLEALKAAENGDFAKADSLVVEAGSCIAEAHSSQTGMLAREASGEELPYSVTMMHGQDHLMTTILLKDVIHHLIELYKRGAK", "length": 105, "reference_go_mf": [], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_bc9e39ccf1ef8617e8d8"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_515_1e2t_assembly1", "enzyme_name": "N-hydroxyarylamine O-acetyltransferase", "ec": ["2.3.1.118"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q00267", "alignment_score": 546.0, "observed_coverage": 0.9963503649635036, "aligned_identity": 1.0, "canonical_span": [0, 273], "sequence": "MTSFLHAYFTRLHCQPLGVPTVEALRTLHLAHNCAIPFENLDVLLPREIQLDETALEEKLLYARRGGYCFELNGLFERALRDIGFNVRSLLGRVILSHPASLPPRTHRLLLVDVEDEQWIADVGFGGQTLTAPLRLQAEIAQQTPHGEYRLMQEGSTWILQFRHHEHWQSMYCFDLGVQQQSDHVMGNFWSAHWPQSHFRHHLLMCRHLPDGGKLTLTNFHFTRYHQGHAVEQVNVPDVPSLYQLLQQQFGLGVNDVKHGFTEAELAAVMAAFDTHPEAGK", "length": 281, "reference_go_mf": ["GO:0004060", "GO:0046990"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_87897291b683b1db1e29"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_516_1qrg_assembly1", "enzyme_name": "carbonate dehydratase (gamma class)", "ec": ["4.2.1.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P40881", "alignment_score": 412.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [41, 247], "sequence": "MMFNKQIFTILILSLSLALAGSGCISEGAEDNVAQEITVDEFSNIRENPVTPWNPEPSAPVIDPTAYIDPQASVIGEVTIGANVMVSPMASIRSDEGMPIFVGDRSNVQDGVVLHALETINEEGEPIEDNIVEVDGKEYAVYIGNNVSLAHQSQVHGPAAVGDDTFIGMQAFVFKSKVGNNCVLEPRSAAIGVTIPDGRYIPAGMVVTSQAEADKLPEVTDDYAYSHTNEAVVYVNVHLAEGYKETS", "length": 247, "reference_go_mf": ["GO:0071890", "GO:0004089", "GO:0050897", "GO:0043199", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_ce9a3b3d330d86104151"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P40881", "alignment_score": 412.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [41, 247], "sequence": "MMFNKQIFTILILSLSLALAGSGCISEGAEDNVAQEITVDEFSNIRENPVTPWNPEPSAPVIDPTAYIDPQASVIGEVTIGANVMVSPMASIRSDEGMPIFVGDRSNVQDGVVLHALETINEEGEPIEDNIVEVDGKEYAVYIGNNVSLAHQSQVHGPAAVGDDTFIGMQAFVFKSKVGNNCVLEPRSAAIGVTIPDGRYIPAGMVVTSQAEADKLPEVTDDYAYSHTNEAVVYVNVHLAEGYKETS", "length": 247, "reference_go_mf": ["GO:0071890", "GO:0004089", "GO:0050897", "GO:0043199", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_ce9a3b3d330d86104151"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_517_1i6p_assembly1", "enzyme_name": "carbonate dehydratase (beta class)", "ec": ["4.2.1.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P61517", "alignment_score": 428.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 215], "sequence": "MKDIDTLISNNALWSKMLVEEDPGFFEKLAQAQKPRFLWIGCSDSRVPAERLTGLEPGELFVHRNVANLVIHTDLNCLSVVQYAVDVLEVEHIIICGHYGCGGVQAAVENPELGLINNWLLHIRDIWFKHSSLLGEMPQERRLDTLCELNVMEQVYNLGHSTIMQSAWKRGQKVTIHGWAYGIHDGLLRDLDVTATNRETLEQRYRHGISNLKLKHANHK", "length": 220, "reference_go_mf": ["GO:0004089", "GO:0042802", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_f0bdcbea00581e885f2c"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_518_1r4z_assembly1", "enzyme_name": "triacylglycerol lipase (EstA)", "ec": ["3.1.1.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P37957", "alignment_score": 358.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [33, 212], "sequence": "MKFVKRRIIALVTILMLSVTSLFALQPSAKAAEHNPVVMVHGIGGASFNFAGIKSYLVSQGWSRDKLYAVDFWDKTGTNYNNGPVLSRFVQKVLDETGAKKVDIVAHSMGGANTLYYIKNLDGGNKVANVVTLGGANRLTTGKALPGTDPNQKILYTSIYSSADMIVMNYLSRLDGARNVQIHGVGHIGLLYSSQVNSLIKEGLNGGGQNTN", "length": 212, "reference_go_mf": ["GO:0016298", "GO:0004806"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_8a9ea05c5d2953b5b143"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_519_1tah_assembly1", "enzyme_name": "triacylglycerol lipase (Pseudomonas family)", "ec": ["3.1.1.3"], "controls": [{"chain": "A", "status": "missing_reference", "selected": null, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_51_1aq2_assembly1", "enzyme_name": "phosphoenolpyruvate carboxykinase (ATP)", "ec": ["4.1.1.49"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P22259", "alignment_score": 1061.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [3, 540], "sequence": "MRVNNGLTPQELEAYGISDVHDIVYNPSYDLLYQEELDPSLTGYERGVLTNLGAVAVDTGIFTGRSPKDKYIVRDDTTRDTFWWADKGKGKNDNKPLSPETWQHLKGLVTRQLSGKRLFVVDAFCGANPDTRLSVRFITEVAWQAHFVKNMFIRPSDEELAGFKPDFIVMNGAKCTNPQWKEQGLNSENFVAFNLTERMQLIGGTWYGGEMKKGMFSMMNYLLPLKGIASMHCSANVGEKGDVAVFFGLSGTGKTTLSTDPKRRLIGDDEHGWDDDGVFNFEGGCYAKTIKLSKEAEPEIYNAIRRDALLENVTVREDGTIDFDDGSKTENTRVSYPIYHIDNIVKPVSKAGHATKVIFLTADAFGVLPPVSRLTADQTQYHFLSGFTAKLAGTERGITEPTPTFSACFGAAFLSLHPTQYAEVLVKRMQAAGAQAYLVNTGWNGTGKRISIKDTRAIIDAILNGSLDNAETFTLPMFNLAIPTELPGVDTKILDPRNTYASPEQWQEKAETLAKLFIDNFDKYTDTPAGAALVAAGPKL", "length": 540, "reference_go_mf": ["GO:0005524", "GO:0005509", "GO:0000287", "GO:0004612"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_08b22ed1c76c9b36319e"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_520_1thg_assembly1", "enzyme_name": "triacylglycerol lipase (type B carboxylestrase)", "ec": ["3.1.1.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P22394", "alignment_score": 1077.0, "observed_coverage": 1.0, "aligned_identity": 0.994475138121547, "canonical_span": [20, 563], "sequence": "MVSKSLFLAAAVNLAGVLAQAPRPSLNGNEVISGVLEGKVDTFKGIPFADPPLNDLRFKHPQPFTGSYQGLKANDFSPACMQLDPGNSLTLLDKALGLAKVIPEEFRGPLYDMAKGTVSMNEDCLYLNVFRPAGTKPDAKLPVMVWIYGGAFVYGSSAAYPGNSYVKESINMGQPVVFVSINYRTGPFGFLGGDAITAEGNTNAGLHDQRKGLEWVSDNIANFGGDPDKVMIFGESAGAMSVAHQLIAYGGDNTYNGKKLFHSAILQSGGPLPYHDSSSVGPDISYNRFAQYAGCDTSASANDTLECLRSKSSSVLHDAQNSYDLKDLFGLLPQFLGFGPRPDGNIIPDAAYELFRSGRYAKVPYISGNQEDEGTAFAPVALNATTTPHVKKWLQYIFYDASEASIDRVLSLYPQTLSVGSPFRTGILNALTPQFKRVAAILSDMLFQSPRRVMLSATKDVNRWTYLSTHLHNLVPFLGTFHGNELIFQFNVNIGPANSYLRYFISFANHHDPNVGTNLLQWDQYTDEGKEMLEIHMTDNVMRTDDYRIEGISNFETDVNLYG", "length": 563, "reference_go_mf": ["GO:0004806"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_11735e76de71cee20a91"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_522_1eh5_assembly1", "enzyme_name": "palmitoyl[protein] hydrolase (type 1)", "ec": ["3.1.2.22"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P45478", "alignment_score": 558.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [27, 306], "sequence": "MASSSCLWLLALAFLLGSCASLALGHLDPPAPLPLVIWHGMGDSCCNPLSMGAIKKMVEKKIPGIHVLSLEIGKTLREDVENSFFLNVNSQVTTVCQILAKDPKLQQGYNAMGFSQGGQFLRAVAQRCPSPPMVNLISVGGQHQGVFGLPRCPGESSHICDFIRKTLNAGAYNKAIQERLVQAEYWHDPIREDIYRNHSIFLADINQERGVNESYKKNLMALKKFVMVKFLNDTIVDPVDSEWFGFYRSGQAKETIPLQESTLYTQDRLGLKAMDKAGQLVFLALEGDHLQLSEEWFYAHIIPFLE", "length": 306, "reference_go_mf": ["GO:0052816", "GO:0008474", "GO:0120146"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_55ec14fe32b46dd881df"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_523_1pja_assembly1", "enzyme_name": "palmitoyl[protein] hydrolase (type 2)", "ec": ["3.1.2.22"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q9UMR5", "alignment_score": 536.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [34, 302], "sequence": "MLGLCGQRLPAAWVLLLLPFLPLLLLAAPAPHRASYKPVIVVHGLFDSSYSFRHLLEYINETHPGTVVTVLDLFDGRESLRPLWEQVQGFREAVVPIMAKAPQGVHLICYSQGGLVCRALLSVMDDHNVDSFISLSSPQMGQYGDTDYLKWLFPTSMRSNLYRICYSPWGQEFSICNYWHDPHHDDLYLNASSFLALINGERDHPNATVWRKNFLRVGHLVLIGGPDDGVITPWQSSFFGFYDANETVLEMEEQLVYLRDSFGLKTLLARGAIVRCPMAGISHTAWHSNRTLYETCIEPWLS", "length": 302, "reference_go_mf": ["GO:0047617", "GO:0052816", "GO:0098599", "GO:0016790"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_b59751fdbb48d1bddb70"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_524_1z4r_assembly1", "enzyme_name": "histone acetyltransferase (GCN5 family)", "ec": ["2.3.1.48"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q92830", "alignment_score": 324.0, "observed_coverage": 0.9938650306748467, "aligned_identity": 1.0, "canonical_span": [496, 658], "sequence": "MAEPSQAPTPAPAAQPRPLQSPAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAPAGSTGTGGPGVGSGGAGSGGDPARPGLSQQQRASQRKAQVRGLPRAKKLEKLGVFSACKANETCKCNGWKNPKPPTAPRMDLQQPAANLSELCRSCEHPLADHVSHLENVSEDEINRLLGMVVDVENLFMSVHKEEDTDTKQVYFYLFKLLRKCILQMTRPVVEGSLGSPPFEKPNIEQGVLNFVQYKFSHLAPRERQTMFELSKMFLLCLNYWKLETPAQFRQRSQAEDVATYKVNYTRWLCYCHVPQSCDSLPRYETTHVFGRSLLRSIFTVTRRQLLEKFRVEKDKLVPEKRTLILTHFPKFLSMLEEEIYGANSPIWESGFTMPPSEGTQLVPRPASVSAAVVPSTPIFSPSMGGGSNSSLSLDSAGAEPMPGEKRTLPENLTLEDAKRLRVMGDIPMELVNEVMLTITDPAAMLGPETSLLSANAARDETARLEERRGIIEFHVIGNSLTPKANRRVLLWLVGLQNVFSHQLPRMPKEYIARLVFDPKHKTLALIKDGRVIGGICFRMFPTQGFTEIVFCAVTSNEQVKGYGTHLMNHLKEYHIKHNILYFLTYADEYAIGYFKKQGFSKDIKVPKSRYLGYIKDYEGATLMECELNPRIPYTELSHIIKKQKEIIKKLIERKQAQIRKVYPGLSCFKEGVRQIPVESVPGIRETGWKPLGKEKGKELKDPDQLYTTLKNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTERLRSRYYVTRKLFVADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLKEGGLIDK", "length": 837, "reference_go_mf": ["GO:0016407", "GO:0003682", "GO:0140297", "GO:0004402", "GO:0042826", "GO:0106229", "GO:0140187", "GO:0010484", "GO:0043992", "GO:0106078", "GO:0140065", "GO:0140064", "GO:0106228", "GO:0120300", "GO:0140186", "GO:0019903", "GO:0061920", "GO:0061733", "GO:0003713"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_fbb7bcf54c04b0a43678"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_528_1it4_assembly1", "enzyme_name": "phospholipase A2 (prokaryotic/fungal)", "ec": ["3.1.1.4"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q6UV28", "alignment_score": 237.0, "observed_coverage": 0.9836065573770492, "aligned_identity": 0.9916666666666667, "canonical_span": [29, 149], "sequence": "MRTTTRTRTTLAAVGAALALGVAAAPPQAAPADKPQVLASFTQTSASSQNAWLAANRNQSAWAAYEFDWSTDLCSQAPDNPFGFPFNTACARHDFGYRNYKAAGSFDANKSRIDSAFYEDMKRVCTGYTGEKNTACNSTAWTYYQAVKIL", "length": 150, "reference_go_mf": ["GO:0004623"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_1ea405a7b33118f5bed9"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_529_1cjy_assembly1", "enzyme_name": "phospholipase A2 (group group IVA)", "ec": ["3.1.1.4"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P47712", "alignment_score": 1208.5, "observed_coverage": 1.0, "aligned_identity": 0.9984202211690363, "canonical_span": [12, 721], "sequence": "MSFIDPYQHIIVEHQYSHKFTVVVLRATKVTKGAFGDMLDTPDPYVELFISTTPDSRKRTRHFNNDINPVWNETFEFILDPNQENVLEITLMDANYVMDETLGTATFTVSSMKVGEKKEVPFIFNQVTEMVLEMSLEVCSCPDLRFSMALCDQEKTFRQQRKEHIRESMKKLLGPKNSEGLHSARDVPVVAILGSGGGFRAMVGFSGVMKALYESGILDCATYVAGLSGSTWYMSTLYSHPDFPEKGPEEINEELMKNVSHNPLLLLTPQKVKRYVESLWKKKSSGQPVTFTDIFGMLIGETLIHNRMNTTLSSLKEKVNTAQCPLPLFTCLHVKPDVSELMFADWVEFSPYEIGMAKYGTFMAPDLFGSKFFMGTVVKKYEENPLHFLMGVWGSAFSILFNRVLGVSGSQSRGSTMEEELENITTKHIVSNDSSDSDDESHEPKGTENEDAGSDYQSDNQASWIHRMIMALVSDSALFNTREGRAGKVHNFMLGLNLNTSYPLSPLSDFATQDSFDDDELDAAVADPDEFERIYEPLDVKSKKIHVVDSGLTFNLPYPLILRPQRGVDLIISFDFSARPSDSSPPFKELLLAEKWAKMNKLPFPKIDPYVFDREGLKECYVFKPKNPDMEKDCPTIIHFVLANINFRKYRAPGVPRETEEEKEIADFDIFDDPESPFSTFNFQYPNQAFKRLHDLMHFNTLNNIDVIKEAMVESIEYRRQNPSRCSVSLSNVEARRFFNKEFLSKPKA", "length": 749, "reference_go_mf": ["GO:0004623", "GO:0016747", "GO:0005509", "GO:0005544", "GO:1902387", "GO:0004622", "GO:0032266", "GO:0070273", "GO:0010314"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_a3309c76e04e3e2b5697"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_52_1b57_assembly1", "enzyme_name": "fructose-bisphosphate aldolase (Class II)", "ec": ["4.1.2.13"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0AB71", "alignment_score": 680.5, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 359], "sequence": "MSKIFDFVKPGVITGDDVQKVFQVAKENNFALPAVNCVGTDSINAVLETAAKVKAPVIVQFSNGGASFIAGKGVKSDVPQGAAILGAISGAHHVHQMAEHYGVPVILHTDHCAKKLLPWIDGLLDAGEKHFAATGKPLFSSHMIDLSEESLQENIEICSKYLERMSKIGMTLEIELGCTGGEEDGVDNSHMDASALYTQPEDVDYAYTELSKISPRFTIAASFGNVHGVYKPGNVVLTPTILRDSQEYVSKKHNLPHNSLNFVFHGGSGSTAQEIKDSVSYGVVKMNIDTDTQWATWEGVLNYYKANEAYLQGQLGNPKGEDQPNKKYYDPRVWLRAGQTSMIARLEKAFQELNAIDVL", "length": 359, "reference_go_mf": ["GO:0004332", "GO:0042802", "GO:0042803", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_ea3e3571e4702088a328"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_530_1jch_assembly2", "enzyme_name": "colicin-E3", "ec": ["3.1.-.-"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00646", "alignment_score": 930.0, "observed_coverage": 1.0, "aligned_identity": 0.9957264957264957, "canonical_span": [83, 551], "sequence": "MSGGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSAVAAPVAFGFPALSTPGAGGLAVSISAGALSAAIADIMAALKGPFKFGLWGVALYGVLPSQIAKDDPNMMSKIVTSLPADDITESPVSSLPLDKATVNVNVRVVDDVKDERQNISVVSGVPMSVPVVDAKPTERPGVFTASIPGAPVLNISVNNSTPAVQTLSPGVTNNTDKDVRPAGFTQGGNTRDAVIRFPKDSGHNAVYVSVSDVLSPDQVKQRQDEENRRQQEWDATHPVEAAERNYERARAELNQANEDVARNQERQAKAVQVYNSRKSELDAANKTLADAIAEIKQFNRFAHDPMAGGHRMWQMAGLKAQRAQTDVNNKQAAFDAAAKEKSDADAALSSAMESRKKKEDKKRSAENNLNDEKNKPRKGFKDYGHDYHPAPKTENIKGLGDLKPGIPKTPKQNGGGKRKRWTGDKGRKIYEWDSQHGELEGYRASDGQHLGSFDPKTGNQLKGPDPKRNIKKYL", "length": 551, "reference_go_mf": ["GO:0016788", "GO:0043022", "GO:0003723", "GO:0044325"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_0298630076ff861dd7f9"}, "alternative_alignments": [{"accession": "P02984", "alignment_score": 7.0, "observed_coverage": 0.010683760683760684, "aligned_identity": 0.8, "canonical_span": [49, 54], "length": 85, "reference_go_mf": ["GO:0015643"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_532_1rhc_assembly1", "enzyme_name": "secondary-alcohol dehydrogenase (coenzyme-F420)", "ec": ["1.1.98.5"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "O93734", "alignment_score": 660.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 330], "sequence": "MKTQIGYFASLEQYRPMDALEQAIRAEKVGFDSVWVDDHFHPWYHDNAQSAQAWAWMGAALQATKKVFISTCITCPIMRYNPAIVAQTFATLRQMYPGRVGVAVGAGEAMNEVPVTGEWPSVPVRQDMTVEAVKVMRMLWESDKPVTFKGDYFTLDKAFLYTKPDDEVPLYFSGMGPKGAKLAGMYGDHLMTVAAAPSTLKNVTIPKFEEGAREAGKDPSKMEHAMLIWYSVDPDYDKAVEALRFWAGCLVPSMFKYKVYDPKEVQLHANLVHCDTIKENYMCATDAEEMIKEIERFKEAGINHFCLGNSSPDVNFGIDIFKEVIPAVRD", "length": 330, "reference_go_mf": ["GO:0016705"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_88ef0e083bfa24ba8fca"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_533_1bh2_assembly1", "enzyme_name": "G-protein alpha subunit, group I (GTPase)", "ec": ["3.6.5.-"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P10824", "alignment_score": 627.0, "observed_coverage": 1.0, "aligned_identity": 0.9968253968253968, "canonical_span": [31, 346], "sequence": "MGCTLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAGYSEEECKQYKAVVYSNTIQSIIAIIRAMGRLKIDFGDAARADDARQLFVLAGAAEEGFMTAELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLDRIAQPNYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAAAYIQCQFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF", "length": 354, "reference_go_mf": ["GO:0010855", "GO:0031749", "GO:0003925", "GO:0001664", "GO:0031821", "GO:0031683", "GO:0019003", "GO:0005525", "GO:0032794", "GO:0003924", "GO:0000287"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_434edf8b81cec09ce86d"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_534_1vom_assembly1", "enzyme_name": "myosin ATPase", "ec": ["5.6.1.8"], "controls": [{"chain": "A", "status": "reference_overlength", "selected": {"accession": "P08799", "alignment_score": 1409.0, "observed_coverage": 1.0, "aligned_identity": 0.9904109589041096, "canonical_span": [1, 747], "sequence": "MNPIHDRTSDYHKYLKVKQGDSDLFKLTVSDKRYIWYNPDPKERDSYECGEIVSETSDSFTFKTVDGQDRQVKKDDANQRNPIKFDGVEDMSELSYLNEPAVFHNLRVRYNQDLIYTYSGLFLVAVNPFKRIPIYTQEMVDIFKGRRRNEVAPHIFAISDVAYRSMLDDRQNQSLLITGESGAGKTENTKKVIQYLASVAGRNQANGSGVLEQQILQANPILEAFGNAKTTRNNNSSRFGKFIEIQFNSAGFISGASIQSYLLEKSRVVFQSETERNYHIFYQLLAGATAEEKKALHLAGPESFNYLNQSGCVDIKGVSDSEEFKITRQAMDIVGFSQEEQMSIFKIIAGILHLGNIKFEKGAGEGAVLKDKTALNAASTVFGVNPSVLEKALMEPRILAGRDLVAQHLNVEKSSSSRDALVKALYGRLFLWLVKKINNVLCQERKAYFIGVLDISGFEIFKVNSFEQLCINYTNEKLQQFFNHHMFKLEQEEYLKEKINWTFIDFGLDSQATIDLIDGRQPPGILALLDEQSVFPNATDNTLITKLHSHFSKKNAKYEEPRFSKTEFGVTHYAGQVMYEIQDWLEKNKDPLQQDLELCFKDSSDNVVTKLFNDPNIASRAKKGANFITVAAQYKEQLASLMATLETTNPHFVRCIIPNNKQLPAKLEDKVVLDQLRCNGVLEGIRITRKGFPNRIIYADFVKRYYLLAPNVPRDAEDSQKATDAVLKHLNIDPEQYRFGITKIFFRAGQLARIEEAREQRISEIIKAIQAATRGWIARKVYKQAREHTVAARIIQQNLRAYIDFKSWPWWKLFSKARPLLKRRNFEKEIKEKEREILELKSNLTDSTTQKDKLEKSLKDTESNVLDLQRQLKAEKETLKAMYDSKDALEAQKRELEIRVEDMESELDEKKLALENLQNQKRSVEEKVRDLEEELQEEQKLRNTLEKLKKKYEEELEEMKRVNDGQSDTISRLEKIKDELQKEVEELTESFSEESKDKGVLEKTRVRLQSELDDLTVRLDSETKDKSELLRQKKKLEEELKQVQEALAAETAAKLAQEAANKKLQGEYTELNEKFNSEVTARSNVEKSKKTLESQLVAVNNELDEEKKNRDALEKKKKALDAMLEEMKDQLESTGGEKKSLYDLKVKQESDMEALRNQISELQSTIAKLEKIKSTLEGEVARLQGELEAEQLAKSNVEKQKKKVELDLEDKSAQLAEETAAKQALDKLKKKLEQELSEVQTQLSEANNKNVNSDSTNKHLETSFNNLKLELEAEQKAKQALEKKRLGLESELKHVNEQLEEEKKQKESNEKRKVDLEKEVSELKDQIEEEVASKKAVTEAKNKKESELDEIKRQYADVVSSRDKSVEQLKTLQAKNEELRNTAEEAEGQLDRAERSKKKAEFDLEEAVKNLEEETAKKVKAEKAMKKAETDYRSTKSELDDAKNVSSEQYVQIKRLNEELSELRSVLEEADERCNSAIKAKKTAESALESLKDEIDAANNAKAKAERKSKELEVRVAELEESLEDKSGTVNVEFIRKKDAEIDDLRARLDRETESRIKSDEDKKNTRKQFADLEAKVEEAQREVVTIDRLKKKLESDIIDLSTQLDTETKSRIKIEKSKKKLEQTLAERRAAEEGSSKAADEEIRKQVWQEVDELRAQLDSERAALNASEKKIKSLVAEVDEVKEQLEDEILAKDKLVKAKRALEVELEEVRDQLEEEEDSRSELEDSKRRLTTEVEDIKKKYDAEVEQNTKLDEAKKKLTDDVDTLKKQLEDEKKKLNESERAKKRLESENEDFLAKLDAEVKNRSRAEKDRKKYEKDLKDTKYKLNDEAATKTQTEIGAAKLEDQIDELRSKLEQEQAKATQADKSKKTLEGEIDNLRAQIEDEGKIKMRLEKEKRALEGELEELRETVEEAEDSKSEAEQSKRLVELELEDARRNLQKEIDAKEIAEDAKSNLQREIVEAKGRLEEESIARTNSDRSRKRLEAEIDALTAQVDAEQKAKNQQIKENKKIETELKEYRKKFGESEKTKTKEFLVVEKLETDYKRAKKEAADEQQQRLTVENDLRKHLSEISLLKDAIDKLQRDHDKTKRELETETASKIEMQRKMADFFGGFKA", "length": 2116, "reference_go_mf": ["GO:0071889", "GO:0051015", "GO:0030554", "GO:0005524", "GO:0030899", "GO:0003774", "GO:0042802", "GO:0000146"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_537_2bvc_assembly1", "enzyme_name": "glutamine synthetase (type I)", "ec": ["6.3.1.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P9WN39", "alignment_score": 950.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [3, 478], "sequence": "MTEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARIDPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISGWWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAADDMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAPVDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV", "length": 478, "reference_go_mf": ["GO:0043531", "GO:0005524", "GO:0050897", "GO:0001968", "GO:0019003", "GO:0004356", "GO:0005525", "GO:0000287", "GO:0030145", "GO:0035375"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_a0323227693bfba2d4aa"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P9WN39", "alignment_score": 950.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [3, 478], "sequence": "MTEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARIDPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISGWWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAADDMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAPVDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV", "length": 478, "reference_go_mf": ["GO:0043531", "GO:0005524", "GO:0050897", "GO:0001968", "GO:0019003", "GO:0004356", "GO:0005525", "GO:0000287", "GO:0030145", "GO:0035375"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_a0323227693bfba2d4aa"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_538_1bib_assembly1", "enzyme_name": "biotin---[acetyl-CoA-carboxylase] ligase", "ec": ["6.3.4.15"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P06709", "alignment_score": 555.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 317], "sequence": "MKDNTVPLKLIALLANGEFHSGEQLGETLGMSRAAINKHIQTLRDWGVDVFTVPGKGYSLPEPIQLLNAKQILGQLDGGSVAVLPVIDSTNQYLLDRIGELKSGDACIAEYQQAGRGRRGRKWFSPFGANLYLSMFWRLEQGPAAAIGLSLVIGIVMAEVLRKLGADKVRVKWPNDLYLQDRKLAGILVELTGKTGDAAQIVIGAGINMAMRRVEESVVNQGWITLQEAGINLDRNTLAAMLIRELRAALELFEQEGLAPYLSRWEKLDNFINRPVKLIIGDKEIFGISRGIDKQGALLLEQDGIIKPWMGGEISLRSAEK", "length": 321, "reference_go_mf": ["GO:0005524", "GO:0009374", "GO:0004077", "GO:0003677", "GO:0003676", "GO:0042803", "GO:0000976"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_d48d98649de9755382ae"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_539_1b7y_assembly1", "enzyme_name": "phenylalanine---tRNA ligase", "ec": ["6.1.1.20"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P27001", "alignment_score": 530.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [85, 350], "sequence": "MLEEALAAIQNARDLEELKALKARYLGKKGLLTQEMKGLSALPLEERRKRGQELNAIKAALEAALEAREKALEEAALKEALERERVDVSLPGASLFSGGLHPITLMERELVEIFRALGYQAVEGPEVESEFFNFDALNIPEHHPARDMWDTFWLTGEGFRLEGPLGEEVEGRLLLRTHTSPMQVRYMVAHTPPFRIVVPGRVFRFEQTDATHEAVFHQLEGLVVGEGIAMAHLKGAIYELAQALFGPDSKVRFQPVYFPFVEPGAQFAVWWPEGGKWLELGGAGMVHPKVFQAVDAYRERLGLPPAYRGVTGFAFGLGVERLAMLRYGIPDIRYFFGGRLKFLEQFKGVL", "length": 350, "reference_go_mf": ["GO:0005524", "GO:0000287", "GO:0004826", "GO:0000049"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_eaa13a9836a71a2d6f20"}, "alternative_alignments": [{"accession": "P27002", "alignment_score": 12.0, "observed_coverage": 0.022641509433962263, "aligned_identity": 1.0, "canonical_span": [267, 273], "length": 785, "reference_go_mf": ["GO:0005524", "GO:0000287", "GO:0004826", "GO:0000049"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_540_1qf6_assembly1", "enzyme_name": "threonine---tRNA ligase", "ec": ["6.1.1.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0A8M3", "alignment_score": 1282.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 642], "sequence": "MPVITLPDGSQRHYDHAVSPMDVALDIGPGLAKACIAGRVNGELVDACDLIENDAQLSIITAKDEEGLEIIRHSCAHLLGHAIKQLWPHTKMAIGPVIDNGFYYDVDLDRTLTQEDVEALEKRMHELAEKNYDVIKKKVSWHEARETFANRGESYKVSILDENIAHDDKPGLYFHEEYVDMCRGPHVPNMRFCHHFKLMKTAGAYWRGDSNNKMLQRIYGTAWADKKALNAYLQRLEEAAKRDHRKIGKQLDLYHMQEEAPGMVFWHNDGWTIFRELEVFVRSKLKEYQYQEVKGPFMMDRVLWEKTGHWDNYKDAMFTTSSENREYCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGSLHGLMRVRGFTQDDAHIFCTEEQIRDEVNGCIRLVYDMYSTFGFEKIVVKLSTRPEKRIGSDEMWDRAEADLAVALEENNIPFEYQLGEGAFYGPKIEFTLYDCLDRAWQCGTVQLDFSLPSRLSASYVGEDNERKVPVMIHRAILGSMERFIGILTEEFAGFFPTWLAPVQVVIMNITDSQSEYVNELTQKLSNAGIRVKADLRNEKIGFKIREHTLRRVPYMLVCGDKEVESGKVAVRTRRGKDLGSMDVNEVIEKLQQEIRSRSLKQLEE", "length": 642, "reference_go_mf": ["GO:0002161", "GO:0004812", "GO:0005524", "GO:0048027", "GO:0000900", "GO:0042803", "GO:0003723", "GO:0004829", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_21e3829be6f7cf88bbee"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_541_1u3f_assembly1", "enzyme_name": "5-formyltetrahydrofolate cyclo-ligase", "ec": ["6.3.3.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P75430", "alignment_score": 328.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 164], "sequence": "MDKNALRKQILQKRMALSTIEKSHLDQKINQKLVAFLTPKPCIKTIALYEPIKNEVTFVDFFFEFLKINQIRAVYPKVISDTEIIFIDQETNTFEPNQIDCFLIPLVGFNKDNYRLGFGKGYYDRYLMQLTRQQPKIGIAYSFQKGDFLADPWDVQLDLIINDE", "length": 164, "reference_go_mf": ["GO:0030272"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_b81a1a149e09441bf87c"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_542_1jof_assembly1", "enzyme_name": "carboxy-cis,cis-muconate cyclase", "ec": ["5.5.1.5"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P38677", "alignment_score": 650.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 366], "sequence": "MPLHHLMIGTWTPPGAIFTVQFDDEKLTCKLIKRTEIPQDEPISWMTFDHERKNIYGAAMKKWSSFAVKSPTEIVHEASHPIGGHPRANDADTNTRAIFLLAAKQPPYAVYANPFYKFAGYGNVFSVSETGKLEKNVQNYEYQENTGIHGMVFDPTETYLYSADLTANKLWTHRKLASGEVELVGSVDAPDPGDHPRWVAMHPTGNYLYALMEAGNRICEYVIDPATHMPVYTHHSFPLIPPGIPDRDPETGKGLYRADVCALTFSGKYMFASSRANKFELQGYIAGFKLRDCGSIEKQLFLSPTPTSGGHSNAVSPCPWSDEWMAITDDQEGWLEIYRWKDEFLHRVARVRIPEPGFGMNAIWYD", "length": 366, "reference_go_mf": ["GO:0017057", "GO:0047768"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_4ab9b2058a0e01ea5e98"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_543_1f75_assembly1", "enzyme_name": "ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific]", "ec": ["2.5.1.31"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "O82827", "alignment_score": 419.5, "observed_coverage": 1.0, "aligned_identity": 0.9953917050691244, "canonical_span": [13, 242], "sequence": "MFPIKKRKAIKNNNINAAQIPKHIAIIMDGNGRWAKQKKMPRIKGHYEGMQTVKKITRYASDLGVKYLTLYAFSTENWSRPKDEVNYLMKLPGDFLNTFLPELIEKNVKVETIGFIDDLPDHTKKAVLEAKEKTKHNTGLTLVFALNYGGRKEIISAVQLIAERYKSGEISLDEISETHFNEYLFTANMPDPELLIRTSGEERLSNFLIWQCSYSEFVFIDEFWPDFNEESLAQCISIYQNRHRRFGGL", "length": 249, "reference_go_mf": ["GO:0008834", "GO:0000287", "GO:0030145"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_324b509b26e9a8f2f6f7"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_544_1f6d_assembly1", "enzyme_name": "UDP-N-acetylglucosamine 2-epimerase", "ec": ["5.1.3.14"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P27828", "alignment_score": 678.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 376], "sequence": "MKVLTVFGTRPEAIKMAPLVHALAKDPFFEAKVCVTAQHREMLDQVLKLFSIVPDYDLNIMQPGQGLTEITCRILEGLKPILAEFKPDVVLVHGDTTTTLATSLAAFYQRIPVGHVEAGLRTGDLYSPWPEEANRTLTGHLAMYHFSPTETSRQNLLRENVADSRIFITGNTVIDALLWVRDQVMSSDKLRSELAANYPFIDPDKKMILVTGHRRESFGRGFEEICHALADIATTHQDIQIVYPVHLNPNVREPVNRILGHVKNVILIDPQEYLPFVWLMNHAWLILTDSGGIQEEAPSLGKPVLVMRDTTERPEAVTAGTVRLVGTDKQRIVEEVTRLLKDENEYQAMSRAHNPYGDGQACSRILEALKNNRISL", "length": 376, "reference_go_mf": ["GO:0042803", "GO:0008761"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_b43aae9a814ba4adc628"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_545_1f2d_assembly1", "enzyme_name": "1-aminocyclopropane-1-carboxylate deaminase", "ec": ["3.5.99.7"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q7M523", "alignment_score": 680.0, "observed_coverage": 0.9970674486803519, "aligned_identity": 1.0, "canonical_span": [1, 341], "sequence": "SGVAKFAKYPLTFGPSPISNLNRLSQHLGSKVNVYAKREDCNSGLAFGGNKLRKLEYIVPDIVEGDYTHLVSIGGRQSNQTRMVAALAAKLGKKCVLIQEDWVPIPEAEKDVYNRVGNIELSRIMGADVRVIEDGFDIGMRKSFANALQELEDAGHKPYPIPAGCSEHKYGGLGFVGFADEVINQEVELGIKFDKIVVCCVTGSTTAGILAGMAQYGRQDDVIAIDASFTSEKTKEQTLRIANNTAKLIGVEHEFKDFTLDTRFAYPCYGVPNEGTIEAIRTCAEQEGVLTDPVYEGKSMQGLIALIKEDYFKPGANVLYVHLGGAPALSAYSSFFPTKTA", "length": 341, "reference_go_mf": ["GO:0008660", "GO:0019148", "GO:0030170"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_dd9fc8061302c7a5d44a"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_546_1eyi_assembly1", "enzyme_name": "fructose-bisphosphatase", "ec": ["3.1.3.11"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00636", "alignment_score": 662.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [7, 338], "sequence": "MTDQAAFDTNIVTLTRFVMEEGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAHLYGIAGSTNVTGDQVKKLDVLSNDLVINVLKSSFATCVLVSEEDKNAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRDVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGKEAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHAAK", "length": 338, "reference_go_mf": ["GO:0016208", "GO:0042132", "GO:0042802", "GO:0046872", "GO:0048029", "GO:0061629"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_79662edbd85f2328fa89"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_547_1ey2_assembly1", "enzyme_name": "homogentisate 1,2-dioxygenase", "ec": ["1.13.11.5"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q93099", "alignment_score": 742.0, "observed_coverage": 1.0, "aligned_identity": 0.9975609756097561, "canonical_span": [1, 440], "sequence": "MAELKYISGFGNECSSEDPRCPGSLPEGQNNPQVCPYNLYAEQLSGSAFTCPRSTNKRSWLYRILPSVSHKPFESIDEGQVTHNWDEVDPDPNQLRWKPFEIPKASQKKVDFVSGLHTLCGAGDIKSNNGLAIHIFLCNTSMENRCFYNSDGDFLIVPQKGNLLIYTEFGKMLVQPNEICVIQRGMRFSIDVFEETRGYILEVYGVHFELPDLGPIGANGLANPRDFLIPIAWYEDRQVPGGYTVINKYQGKLFAAKQDVSPFNVVAWHGNYTPYKYNLKNFMVINSVAFDHADPSIFTVLTAKSVRPGVAIADFVIFPPRWGVADKTFRPPYYHRNCMSEFMGLIRGHYEAKQGGFLPGGGSLHSTMTPHGPDADCFEKASKVKLAPERIADGTMAFMFESSLSLAVTKWGLKASRCLDENYHKCWEPLKSHFTPNSRNPAEPN", "length": 445, "reference_go_mf": ["GO:0004411", "GO:0042802"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_792903770485665af8c5"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_548_1exp_assembly1", "enzyme_name": "endo-1,4-beta-xylanase (glycosyl hydrolase 10)", "ec": ["3.2.1.8"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P07986", "alignment_score": 615.0, "observed_coverage": 1.0, "aligned_identity": 0.9903846153846154, "canonical_span": [41, 353], "sequence": "MPRTTPAPGHPARGARTALRTTRRRAATLVVGATVVLPAQAATTLKEAADGAGRDFGFALDPNRLSEAQYKAIADSEFNLVVAENAMKWDATEPSQNSFSFGAGDRVASYAADTGKELYGHTLVWHSQLPDWAKNLNGSAFESAMVNHVTKVADHFEGKVASWDVVNEAFADGDGPPQDSAFQQKLGNGYIETAFRAARAADPTAKLCINDYNVEGINAKSNSLYDLVKDFKARGVPLDCVGFQSHLIVGQVPGDFRQNLQRFADLGVDVRITELDIRMRTPSDATKLATQAADYKKVVQACMQVTRCQGVTVWGITDKYSWVPDVFPGEGAALVWDASYAKKPAYAAVMEAFGASPTPTPTTPTPTPTTPTPTPTSGPAGCQVLWGVNQWNTGFTANVTVKNTSSAPVDGWTLTFSFPSGQQVTQAWSSTVTQSGSAVTVRNAPWNGSIPAGGTAQFGFNGSHTGTNAAPTAFSLNGTPCTVG", "length": 484, "reference_go_mf": ["GO:0016162", "GO:0031176", "GO:0030247"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_0c561d357dfebc0d7304"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_549_1exn_assembly1", "enzyme_name": "exodeoxyribonuclease (lambda-induced)", "ec": ["3.1.11.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P06229", "alignment_score": 510.0, "observed_coverage": 0.9887640449438202, "aligned_identity": 1.0, "canonical_span": [23, 290], "sequence": "MSKSWGKFIEEEEAEMASRRNLMIVDGTNLGFRFKHNNSKKPFASSYVSTIQSLAKSYSARTTIVLGDKGKSVFRLEHLPEYKGNRDEKYAQRTEEEKALDEQFFEYLKDAFELCKTTFPTFTIRGVEADDMAAYIVKLIGHLYDHVWLISTDGDWDTLLTDKVSRFSFTTRREYHLRDMYEHHNVDDVEQFISLKAIMGDLGDNIRGVEGIGAKRGYNIIREFGNVLDIIDQLPLPGKQKYIQNLNASEELLFRNLILVDLPTYCVDAIAAVGQDVLDKFTKDILEIAEQ", "length": 291, "reference_go_mf": ["GO:0035312", "GO:0008409", "GO:0017108", "GO:0003677", "GO:0004529", "GO:0051908", "GO:1990238", "GO:0046872"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_c93d5bd8bf6d7e161236"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_54_1qfe_assembly1", "enzyme_name": "3-dehydroquinate dehydratase (type I)", "ec": ["4.2.1.10"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P24670", "alignment_score": 501.0, "observed_coverage": 1.0, "aligned_identity": 0.996031746031746, "canonical_span": [0, 252], "sequence": "MKTVTVKNLIIGEGMPKIIVSLMGRDINSVKAEALAYREATFDILEWRVDHFMDIASTQSVLTAARVIRDAMPDIPLLFTFRSAKEGGEQTITTQHYLTLNRAAIDSGLVDMIDLELFTGDADVKATVDYAHAHNVYVVMSNHDFHQTPSAEEMVLRLRKMQALGADIPKIAVMPQSKHDVLTLLTATLEMQQHYADRPVITMSMAKEGVISRLAGEVFGSAATFGAVKQASAPGQIAVNDLRSVLMILHNA", "length": 252, "reference_go_mf": ["GO:0003855"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_6e2f32d064d86ca58960"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_550_1fq0_assembly1", "enzyme_name": "2-dehydro-3-deoxy-phosphogluconate aldolase", "ec": ["4.1.2.14"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0A955", "alignment_score": 426.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 213], "sequence": "MKNWKTSAESILTTGPVVPVIVVKKLEHAVPMAKALVAGGVRVLEVTLRTECAVDAIRAIAKEVPEAIVGAGTVLNPQQLAEVTEAGAQFAISPGLTEPLLKAATEGTIPLIPGISTVSELMLGMDYGLKEFKFFPAEANGGVKALQAIAGPFSQVRFCPTGGISPANYRDYLALKSVLCIGGSWLVPADALEAGDYDRITKLAREAVEGAKL", "length": 213, "reference_go_mf": ["GO:0106009", "GO:0008700", "GO:0008675", "GO:0016832", "GO:0042802", "GO:0008948", "GO:0016833"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_133499b2b00db3eb15ef"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_551_1foh_assembly1", "enzyme_name": "phenol 2-monooxygenase", "ec": ["1.14.13.7"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P15245", "alignment_score": 1283.0, "observed_coverage": 1.0, "aligned_identity": 0.9984591679506933, "canonical_span": [1, 663], "sequence": "MTKYSESYCDVLIVGAGPAGLMAARVLSEYVRQKPDLKVRIIDKRSTKVYNGQADGLQCRTLESLKNLGLADKILSEANDMSTIALYNPDENGHIRRTDRIPDTLPGISRYHQVVLHQGRIERHILDSIAEISDTRIKVERPLIPEKMEIDSSKAEDPEAYPVTMTLRYMSDHESTPLQFGHKTENSLFHSNLQTQEEEDANYRLPEGKEAGEIETVHCKYVIGCDGGHSWVRRTLGFEMIGEQTDYIWGVLDAVPASNFPDIRSPCAIHSAESGSIMIIPRENNLVRFYVQLQARAEKGGRVDRTKFTPEVVIANAKKIFHPYTFDVQQLDWFTAYHIGQRVTEKFSKDERVFIAGDACHTHSPKAGQGMNTSMMDTYNLGWKLGLVLTGRAKRDILKTYEEERHAFAQALIDFDHQFSRLFSGRPAKDVADEMGVSMDVFKEAFVKGNEFASGTAINYDENLVTDKKSSKQELAKNCVVGTRFKSQPVVRHSEGLWMHFGDRLVTDGRFRIIVFAGKATDATQMSRIKKFSAYLDSENSVISLYTPKVSDRNSRIDVITIHSCHRDDIEMHDFPAPALHPKWQYDFIYADCDSWHHPHPKSYQAWGVDETKGAVVVVRPDGYTSLVTDLEGTAEIDRYFSGILVEPKEKSGAQTEADWTKSTA", "length": 665, "reference_go_mf": ["GO:0071949", "GO:0018662"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_e00ce116b80e34190a16"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_552_1fgh_assembly1", "enzyme_name": "aconitate hydratase", "ec": ["4.2.1.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P20004", "alignment_score": 1466.0, "observed_coverage": 0.99734395750332, "aligned_identity": 0.9840213049267643, "canonical_span": [28, 779], "sequence": "MAPYSLLVSRLQKALGARQYHVASVLCQRAKVAMSHFEPNEYIRYDLLEKNINIVRKRLNRPLTLSEKIVYGHLDDPANQEIERGKTYLRLRPDRVAMQDATAQMAMLQFISSGLPKVAVPSTIHCDHLIEAQLGGEKDLRRAKDINQEVYNFLATAGAKYGVGFWRPGSGIIHQIILENYAYPGVLLIGTDSHTPNGGGLGGICIGVGGADAVDVMAGIPWELKCPKVIGVKLTGSLSGWTSPKDVILKVAGILTVKGGTGAIVEYHGPGVDSISCTGMATICNMGAEIGATTSVFPYNHRMKKYLSKTGRADIANLADEFKDHLVPDSGCHYDQLIEINLSELKPHINGPFTPDLAHPVAEVGSVAEKEGWPLDIRVGLIGSCTNSSYEDMGRSAAVAKQALAHGLQCKSQFTITPGSEQIRATIERDGYAQILRDVGGIVLANACGPCIGQWDRKDIKKGEKNTIVTSYNRNFTGRNDANPETHAFVTSPEIVTALAIAGTLKFNPETDFLTGKDGKKFKLEAPDADELPRAEFDPGQDTYQHPPKDSSGQQVDVSPTSQRLQLLEPFDKWDGRDLEDLQILIKVKGKCTTDHISAAGPWLKFRGHLDNISNNLLIGAINVENGKANSVRNAVTQEFGPVPDTARYYKKHGIRWVVIGDENYGEGSSREHAALEPRHLGGRAIITKSFARIHETNLKKQGLLPLTFADPADYNKIHPVDKLTIKGLKDFAPGKPLTCIIKHPNGTQETILLNHTFNETQIEWFRAGSALNRMKELQK", "length": 780, "reference_go_mf": ["GO:0051538", "GO:0051539", "GO:0003994", "GO:0008198", "GO:0005506"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_d4ee5b9ffd3490b295e2"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_554_1f8x_assembly1", "enzyme_name": "nucleoside deoxyribosyltransferase", "ec": ["2.4.2.6"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q9R5V5", "alignment_score": 312.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 157], "sequence": "MPKKTIYFGAGWFTDRQNKAYKEAMEALKENPTIDLENSYVPLDNQYKGIRVDEHPEYLHDKVWATATYNNDLNGIKTNDIMLGVYIPDEEDVGLGMELGYALSQGKYVLLVIPDEDYGKPINLMSWGVSDNVIKMSQLKDFNFNKPRFDFYEGAVY", "length": 157, "reference_go_mf": ["GO:0050144"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_76a4dd122800764de167"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_556_1esc_assembly1", "enzyme_name": "esterase (estA)", "ec": ["3.1.1.-"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P22266", "alignment_score": 604.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [42, 344], "sequence": "MSSAMRKTTNSPVVRRLTAAAVALGSCLALAGPAGSAGAAPADPVPTVFFGDSYTANFGIAPVTNQDSERGWCFQAKENYPAVATRSLADKGITLDVQADVSCGGALIHHFWEKQELPFGAGELPPQQDALKQDTQLTVGSLGGNTLGFNRILKQCSDELRKPSLLPGDPVDGDEPAAKCGEFFGTGDGKQWLDDQFERVGAELEELLDRIGYFAPDAKRVLVGYPRLVPEDTTKCLTAAPGQTQLPFADIPQDALPVLDQIQKRLNDAMKKAAADGGADFVDLYAGTGANTACDGADRGIGGLLEDSQLELLGTKIPWYAHPNDKGRDIQAKQVADKIEEILNR", "length": 345, "reference_go_mf": ["GO:0016788"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_5238fc91b9220ff3130c"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_557_1eq2_assembly1", "enzyme_name": "ADP-glyceromanno-heptose 6-epimerase", "ec": ["5.1.3.20"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P67910", "alignment_score": 510.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 307], "sequence": "MIIVTGGAGFIGSNIVKALNDKGITDILVVDNLKDGTKFVNLVDLNIADYMDKEDFLIQIMAGEEFGDVEAIFHEGACSSTTEWDGKYMMDNNYQYSKELLHYCLEREIPFLYASSAATYGGRTSDFIESREYEKPLNVYGYSKFLFDEYVRQILPEANSQIVGFRYFNVYGPREGHKGSMASVAFHLNTQLNNGESPKLFEGSENFKRDFVYVGDVADVNLWFLENGVSGIFNLGTGRAESFQAVADATLAYHKKGQIEYIPFPDKLKGRYQAFTQADLTNLRAAGYDKPFKTVAEGVTEYMAWLNRDA", "length": 310, "reference_go_mf": ["GO:0008712", "GO:0070401"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_1e9fb667282a6f8f4de1"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_558_1d2t_assembly1", "enzyme_name": "non-specific acid phosphatases (class A)", "ec": ["3.1.3.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q9S1A6", "alignment_score": 437.5, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [24, 248], "sequence": "MKKRVLAVCFAALFSSQALALVATGNDTTTKPDLYYLKNSEAINSLALLPPPPAVGSIAFLNDQAMYEQGRLLRNTERGKLAAEDANLSSGGVANAFSGAFGSPITEKDAPALHKLLTNMIEDAGDLATRSAKDHYMRIRPFAFYGVSTCNTTEQDKLSKNGSYPSGHTSIGWATALVLAEINPQRQNEILKRGYELGQSRVICGYHWQSDVDAARVVGSAVVATLHTNPAFQQQLQKAKAEFAQHQKK", "length": 249, "reference_go_mf": ["GO:0003993"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_9f070da71beee16134bc"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_559_1js4_assembly1", "enzyme_name": "cellulase (GH9)", "ec": ["3.2.1.4"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P26221", "alignment_score": 1210.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [46, 651], "sequence": "MSVTEPPPRRRGRHSRARRFLTSLGATAALTAGMLGVPLATGTAHAEPAFNYAEALQKSMFFYEAQRSGKLPENNRVSWRGDSGLNDGADVGLDLTGGWYDAGDHVKFGFPMAFTATMLAWGAIESPEGYIRSGQMPYLKDNLRWVNDYFIKAHPSPNVLYVQVGDGDADHKWWGPAEVMPMERPSFKVDPSCPGSDVAAETAAAMAASSIVFADDDPAYAATLVQHAKQLYTFADTYRGVYSDCVPAGAFYNSWSGYQDELVWGAYWLYKATGDDSYLAKAEYEYDFLSTEQQTDLRSYRWTIAWDDKSYGTYVLLAKETGKQKYIDDANRWLDYWTVGVNGQRVPYSPGGMAVLDTWGALRYAANTAFVALVYAKVIDDPVRKQRYHDFAVRQINYALGDNPRNSSYVVGFGNNPPRNPHHRTAHGSWTDSIASPAENRHVLYGALVGGPGSPNDAYTDDRQDYVANEVATDYNAGFSSALAMLVEEYGGTPLADFPPTEEPDGPEIFVEAQINTPGTTFTEIKAMIRNQSGWPARMLDKGTFRYWFTLDEGVDPADITVSSAYNQCATPEDVHHVSGDLYYVEIDCTGEKIFPGGQSEHRREVQFRIAGGPGWDPSNDWSFQGIGNELAPAPYIVLYDDGVPVWGTAPEEGEEPGGGEGPGGGEEPGEDVTPPSAPGSPAVRDVTSTSAVLTWSASSDTGGSGVAGYDVFLRAGTGQEQKVGSTTRTSFTLTGLEPDTTYIAAVVARDNAGNVSQRSTVSFTTLAENGGGPDASCTVGYSTNDWDSGFTASIRITYHGTAPLSSWELSFTFPAGQQVTHGWNATWRQDGAAVTATPMSWNSSLAPGATVEVGFNGSWSGSNTPPTDFTLNGEPCALA", "length": 880, "reference_go_mf": ["GO:0008810", "GO:0030248"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_0e997f70382eb1f8c86d"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_55_1gu1_assembly1", "enzyme_name": "3-dehydroquinate dehydratase (type II)", "ec": ["4.2.1.10"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P15474", "alignment_score": 298.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [2, 151], "sequence": "MPRSLANAPIMILNGPNLNLLGQRQPEIYGSDTLADVEALCVKAAAAHGGTVDFRQSNHEGELVDWIHEARLNHCGIVINPAAYSHTSVAILDALNTCDGLPVVEVHISNIHQREPFRHHSYVSQRADGVVAGCGVQGYVFGVERIAALAGAGSARA", "length": 157, "reference_go_mf": ["GO:0003855"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_ee6cffc50e191211eba2"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_562_1aa6_assembly1", "enzyme_name": "formate dehydrogenase", "ec": ["1.17.1.9"], "controls": [{"chain": "A", "status": "reference_nonstandard", "selected": {"accession": "P07658", "alignment_score": 1371.5, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 715], "sequence": "MKKVVTVCPYCASGCKINLVVDNGKIVRAEAAQGKTNQGTLCLKGYYGWDFINDTQILTPRLKTPMIRRQRGGKLEPVSWDEALNYVAERLSAIKEKYGPDAIQTTGSSRGTGNETNYVMQKFARAVIGTNNVDCCARVUHGPSVAGLHQSVGNGAMSNAINEIDNTDLVFVFGYNPADSHPIVANHVINAKRNGAKIIVCDPRKIETARIADMHIALKNGSNIALLNAMGHVIIEENLYDKAFVASRTEGFEEYRKIVEGYTPESVEDITGVSASEIRQAARMYAQAKSAAILWGMGVTQFYQGVETVRSLTSLAMLTGNLGKPHAGVNPVRGQNNVQGACDMGALPDTYPGYQYVKDPANREKFAKAWGVESLPAHTGYRISELPHRAAHGEVRAAYIMGEDPLQTDAELSAVRKAFEDLELVIVQDIFMTKTASAADVILPSTSWGEHEGVFTAADRGFQRFFKAVEPKWDLKTDWQIISEIATRMGYPMHYNNTQEIWDELRHLCPDFYGATYEKMGELGFIQWPCRDTSDADQGTSYLFKEKFDTPNGLAQFFTCDWVAPIDKLTDEYPMVLSTVREVGHYSCRSMTGNCAALAALADEPGYAQINTEDAKRLGIEDEALVWVHSRKGKIITRAQVSDRPNKGAIYMTYQWWIGACNELVTENLSPITKTPEYKYCAVRVEPIADQRAAEQYVIDEYNKLKTRLREAALA", "length": 715, "reference_go_mf": ["GO:0051539", "GO:0008863", "GO:0043546", "GO:0016903"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_563_1kqf_assembly1", "enzyme_name": "formate dehydrogenase (nitrate-inducible)", "ec": ["1.17.5.3"], "controls": [{"chain": "A", "status": "reference_nonstandard", "selected": {"accession": "P24183", "alignment_score": 1956.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [33, 1015], "sequence": "MDVSRRQFFKICAGGMAGTTVAALGFAPKQALAQARNYKLLRAKEIRNTCTYCSVGCGLLMYSLGDGAKNAREAIYHIEGDPDHPVSRGALCPKGAGLLDYVNSENRLRYPEYRAPGSDKWQRISWEEAFSRIAKLMKADRDANFIEKNEQGVTVNRWLSTGMLCASGASNETGMLTQKFARSLGMLAVDNQARVUHGPTVASLAPTFGRGAMTNHWVDIKNANVVMVMGGNAAEAHPVGFRWAMEAKNNNDATLIVVDPRFTRTASVADIYAPIRSGTDITFLSGVLRYLIENNKINAEYVKHYTNASLLVRDDFAFEDGLFSGYDAEKRQYDKSSWNYQLDENGYAKRDETLTHPRCVWNLLKEHVSRYTPDVVENICGTPKADFLKVCEVLASTSAPDRTTTFLYALGWTQHTVGAQNIRTMAMIQLLLGNMGMAGGGVNALRGHSNIQGLTDLGLLSTSLPGYLTLPSEKQVDLQSYLEANTPKATLADQVNYWSNYPKFFVSLMKSFYGDAAQKENNWGYDWLPKWDQTYDVIKYFNMMDEGKVTGYFCQGFNPVASFPDKNKVVSCLSKLKYMVVIDPLVTETSTFWQNHGESNDVDPASIQTEVFRLPSTCFAEEDGSIANSGRWLQWHWKGQDAPGEARNDGEILAGIYHHLRELYQSEGGKGVEPLMKMSWNYKQPHEPQSDEVAKENNGYALEDLYDANGVLIAKKGQLLSSFAHLRDDGTTASSCWIYTGSWTEQGNQMANRDNSDPSGLGNTLGWAWAWPLNRRVLYNRASADINGKPWDPKRMLIQWNGSKWTGNDIPDFGNAAPGTPTGPFIMQPEGMGRLFAINKMAEGPFPEHYEPIETPLGTNPLHPNVVSNPVVRLYEQDALRMGKKEQFPYVGTTYRLTEHFHTWTKHALLNAIAQPEQFVEISETLAAAKGINNGDRVTVSSKRGFIRAVAVVTRRLKPLNVNGQQVETVGIPIHWGFEGVARKGYIANTLTPNVGDANSQTPEYKAFLVNIEKA", "length": 1015, "reference_go_mf": ["GO:0051539", "GO:0009055", "GO:0047111", "GO:0008863", "GO:0036397", "GO:0030151", "GO:0043546", "GO:0008430"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": [{"accession": "P0AEK7", "alignment_score": 9.0, "observed_coverage": 0.0061162079510703364, "aligned_identity": 0.8333333333333334, "canonical_span": [182, 188], "length": 217, "reference_go_mf": ["GO:0009055", "GO:0008863", "GO:0036397", "GO:0020037"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, {"accession": "P0AAJ3", "alignment_score": 8.0, "observed_coverage": 0.013251783893985729, "aligned_identity": 0.5384615384615384, "canonical_span": [21, 34], "length": 294, "reference_go_mf": ["GO:0051539", "GO:0009055", "GO:0036397"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}, {"chain": "B", "status": "assigned", "selected": {"accession": "P0AEK7", "alignment_score": 432.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 217], "sequence": "MSKSKMIVRTKFIDRACHWTVVICFFLVALSGISFFFPTLQWLTQTFGTPQMGRILHPFFGIAIFVALMFMFVRFVHHNIPDKKDIPWLLNIVEVLKGNEHKVADVGKYNAGQKMMFWSIMSMIFVLLVTGVIIWRPYFAQYFPMQVVRYSLLIHAAAGIILIHAILIHMYMAFWVKGSIKGMIEGKVSRRWAKKHHPRWYREIEKAEAKKESEEGI", "length": 217, "reference_go_mf": ["GO:0009055", "GO:0008863", "GO:0036397", "GO:0020037"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_0a1911354a4507fa30d4"}, "alternative_alignments": [{"accession": "P0AAJ3", "alignment_score": 11.0, "observed_coverage": 0.06018518518518518, "aligned_identity": 0.6153846153846154, "canonical_span": [260, 273], "length": 294, "reference_go_mf": ["GO:0051539", "GO:0009055", "GO:0036397"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, {"accession": "P24183", "alignment_score": 9.0, "observed_coverage": 0.027777777777777776, "aligned_identity": 0.8333333333333334, "canonical_span": [543, 549], "length": 1015, "reference_go_mf": ["GO:0051539", "GO:0009055", "GO:0047111", "GO:0008863", "GO:0036397", "GO:0030151", "GO:0043546", "GO:0008430"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_564_1a4y_assembly1", "enzyme_name": "ribonuclease V", "ec": ["3.1.27.8"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P03950", "alignment_score": 246.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [24, 147], "sequence": "MVMGLGVLLLVFVLGLGLTPPTLAQDNSRYTHFLTQHYDAKPQGRDDRYCESIMRRRGLTSPCKDINTFIHGNKRSIKAICENKNGNPHRENLRISKSSFQVTTCKLHGGSPWPPCQYRATAGFRNVVVACENGLPVHLDQSIFRRP", "length": 147, "reference_go_mf": ["GO:0003779", "GO:0005507", "GO:0003677", "GO:0004519", "GO:0008201", "GO:0042277", "GO:0042803", "GO:0048018", "GO:0043022", "GO:0004521", "GO:0004540", "GO:0019843", "GO:0005102", "GO:0004549"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_909597435fc4ddd2cdcb"}, "alternative_alignments": [{"accession": "P13489", "alignment_score": 8.0, "observed_coverage": 0.032520325203252036, "aligned_identity": 1.0, "canonical_span": [44, 48], "length": 461, "reference_go_mf": ["GO:0008428"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_565_1a79_assembly1", "enzyme_name": "tRNA-intron lyase", "ec": ["4.6.1.16"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q58819", "alignment_score": 342.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [8, 179], "sequence": "MVRDKMGKKITGLLDGDRVIVFDKNGISKLSARHYGNVEGNFLSLSLVEALYLINLGWLEVKYKDNKPLSFEELYEYARNVEERLCLKYLVYKDLRTRGYIVKTGLKYGADFRLYERGANIDKEHSVYLVKVFPEDSSFLLSELTGFVRVAHSVRKKLLIAIVDADGDIVYYNMTYVKP", "length": 179, "reference_go_mf": ["GO:0004519", "GO:0003676", "GO:0000213"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_0a9831540796113a2714"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_566_1gcu_assembly1", "enzyme_name": "biliverdin reductase", "ec": ["1.3.1.24"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P46844", "alignment_score": 584.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 292], "sequence": "MDAEPKRKFGVVVVGVGRAGSVRLRDLKDPRSAAFLNLIGFVSRRELGSLDEVRQISLEDALRSQEIDVAYICSESSSHEDYIRQFLQAGKHVLVEYPMTLSFAAAQELWELAAQKGRVLHEEHVELLMEEFEFLRREVLGKELLKGSLRFTASPLEEERFGFPAFSGISRLTWLVSLFGELSLISATLEERKEDQYMKMTVQLETQNKGLLSWIEEKGPGLKRNRYVNFQFTSGSLEEVPSVGVNKNIFLKDQDIFVQKLLDQVSAEDLAAEKKRIMHCLGLASDIQKLCHQKK", "length": 295, "reference_go_mf": ["GO:0106276", "GO:0106277", "GO:0004074", "GO:0000166", "GO:0004674", "GO:0000978", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_efbb8312333344f8de21"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_568_1ga8_assembly1", "enzyme_name": "lipopolysaccharide 3-alpha-galactosyltransferase", "ec": ["2.4.1.44"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q93EK7", "alignment_score": 498.0, "observed_coverage": 1.0, "aligned_identity": 0.992619926199262, "canonical_span": [1, 282], "sequence": "MDIVFAADDNYAAYLCVAAKSVEAAHPDTEIRFHVLDAGISEANRAAVAANLRGGGGNIRFIDVNPEDFAGFPLNIRHISITTYARLKLGEYIADCDKVLYLDIDVLVRDSLTPLWDTDLGDNWLGACIDLFVERQEGYKQKIGMADGEYYFNAGVLLINLKKWRRHDIFKMSCEWVEQYKDVMQYQDQDILNGLFKGGVCYANSRFNFMPTNYAFMANRFASRHTDPLYRDRTNTVMPVAVSHYCGPAKPWHRDCTAWGAERFTELAGSLTTVPEEWRGKLAVPHRMFSTKRMLQRWRRKLSARFLRKIY", "length": 311, "reference_go_mf": ["GO:0016757"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_1e5de6f9038fc0a5082e"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_56_1ze1_assembly1", "enzyme_name": "tRNA-pseudouridine synthase", "ec": ["5.4.99.25"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q9WZW0", "alignment_score": 607.0, "observed_coverage": 1.0, "aligned_identity": 0.9902597402597403, "canonical_span": [0, 308], "sequence": "MKHGILVAYKPKGPTSHDVVDEVRKKLKTRKVGHGGTLDPFACGVLIIGVNQGTRILEFYKDLKKVYWVKMRLGLITETFDITGEVVEERECNVTEEEIREAIFSFVGEYDQVPPAYSAKKYKGERLYKLAREGKIINLPPKRVKIFKIWDVNIEGRDVSFRVEVSPGTYIRSLCMDIGYKLGCGATAVELVRESVGPHTIEESLNVFEAAPEEIENRIIPLEKCLEWLPRVVVHQESTKMILNGSQIHLEMLKEWDGFKKGEVVRVFNEEGRLLALAEAERNSSFLETLRKHERNERVLTLRKVFNTR", "length": 309, "reference_go_mf": ["GO:0009982", "GO:0003723", "GO:0160148"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_89d96b80d248ad151d57"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_570_1fr8_assembly1", "enzyme_name": "\u03b2-N-acetylglucosaminylglycopeptide \u03b2-1,4-galactosyltransferase", "ec": ["2.4.1.38"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P08037", "alignment_score": 542.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [131, 402], "sequence": "MKFREPLLGGSAAMPGASLQRACRLLVAVCALHLGVTLVYYLAGRDLRRLPQLVGVHPPLQGSSHGAAAIGQPSGELRLRGVAPPPPLQNSSKPRSRAPSNLDAYSHPGPGPGPGSNLTSAPVPSTTTRSLTACPEESPLLVGPMLIEFNIPVDLKLVEQQNPKVKLGGRYTPMDCISPHKVAIIIPFRNRQEHLKYWLYYLHPILQRQQLDYGIYVINQAGESMFNRAKLLNVGFKEALKDYDYNCFVFSDVDLIPMNDHNTYRCFSQPRHISVAMDKFGFSLPYVQYFGGVSALSKQQFLSINGFPNNYWGWGGEDDDIYNRLAFRGMSVSRPNAVIGKCRMIRHSRDKKNEPNPQRFDRIAHTKETMLSDGLNSLTYMVLEVQRYPLYTKITVDIGTPS", "length": 402, "reference_go_mf": ["GO:0043014", "GO:0003831", "GO:0048487", "GO:0042802", "GO:0004461", "GO:0030145", "GO:0003945", "GO:0035250"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_1a21449bd4b2bf9e7f80"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_571_1gdh_assembly1", "enzyme_name": "glycerate dehydrogenase", "ec": ["1.1.1.29"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P36234", "alignment_score": 640.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [2, 322], "sequence": "MSKKKILITWPLPEAAMARARESYDVIAHGDDPKITIDEMIETAKSVDALLITLNEKCRKEVIDRIPENIKCISTYSIGFDHIDLDACKARGIKVGNAPHGVTVATAEIAMLLLLGSARRAGEGEKMIRTRSWPGWEPLELVGEKLDNKTLGIYGFGSIGQALAKRAQGFDMDIDYFDTHRASSSDEASYQATFHDSLDSLLSVSQFFSLNAPSTPETRYFFNKATIKSLPQGAIVVNTARGDLVDNELVVAALEAGRLAYAGFDVFAGEPNINEGYYDLPNTFLFPHIGSAATQAREDMAHQANDLIDALFGGADMSYALA", "length": 322, "reference_go_mf": ["GO:0030267", "GO:0008465", "GO:0051287"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_656511cbf54252c0d818"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_572_1o9i_assembly1", "enzyme_name": "catalase (manganese dependent)", "ec": ["1.11.1.6"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P60355", "alignment_score": 529.0, "observed_coverage": 1.0, "aligned_identity": 0.9962406015037594, "canonical_span": [0, 266], "sequence": "MFKHTRKLQYNAKPDRSDPIMARRLQESLGGQWGETTGMMSYLSQGWASTGAEKYKDLLLDTGTEEMAHVEMISTMIGYLLEDAPFGPEDLKRDPSLATTMAGMDPEHSLVHGLNASLNNPNGAAWNAGYVTSSGNLVADMRFNVVRESEARLQVSRLYSMTEDEGVRDMLKFLLARETQHQLQFMKAQEELEEKYGIIVPGDMKEIEHSEFSHVLMNFSDGDGSKAFEGQVAKDGEKFTYQENPEAMGGIPHIKPGDPRLHNHQG", "length": 266, "reference_go_mf": ["GO:0004096"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_6bc4cb3f4ff216a40cce"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_573_1iph_assembly1", "enzyme_name": "catalase (HPII)", "ec": ["1.11.1.6"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P21179", "alignment_score": 1454.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [26, 753], "sequence": "MSQHNEKNPHQHQSPLHDSSEAKPGMDSLAPEDGSHRPAAEPTPPGAQPTAPGSLKAPDTRNEKLNSLEDVRKGSENYALTTNQGVRIADDQNSLRAGSRGPTLLEDFILREKITHFDHERIPERIVHARGSAAHGYFQPYKSLSDITKADFLSDPNKITPVFVRFSTVQGGAGSADTVRDIRGFATKFYTEEGIFDLVGNNTPIFFIQDAHKFPDFVHAVKPEPHWAIPQGQSAHDTFWDYVSLQPETLHNVMWAMSDRGIPRSYRTMEGFGIHTFRLINAEGKATFVRFHWKPLAGKASLVWDEAQKLTGRDPDFHRRELWEAIEAGDFPEYELGFQLIPEEDEFKFDFDLLDPTKLIPEELVPVQRVGKMVLNRNPDNFFAENEQAAFHPGHIVPGLDFTNDPLLQGRLFSYTDTQISRLGGPNFHEIPINRPTCPYHNFQRDGMHRMGIDTNPANYEPNSINDNWPRETPPGPKRGGFESYQERVEGNKVRERSPSFGEYYSHPRLFWLSQTPFEQRHIVDGFSFELSKVVRPYIRERVVDQLAHIDLTLAQAVAKNLGIELTDDQLNITPPPDVNGLKKDPSLSLYAIPDGDVKGRVVAILLNDEVRSADLLAILKALKAKGVHAKLLYSRMGEVTADDGTVLPIAATFAGAPSLTVDAVIVPCGNIADIADNGDANYYLMEAYKHLKPIALAGDARKFKATIKIADQGEEGIVEADSADGSFMDELLTLMAAHRVWSRIPKIDKIPA", "length": 753, "reference_go_mf": ["GO:0004096", "GO:0020037", "GO:0042802", "GO:0005506"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_73d0229f6cf733f82efd"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_574_1kas_assembly1", "enzyme_name": "beta-ketoacyl-acyl-carrier-protein synthase II", "ec": ["2.3.1.179"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0AAI5", "alignment_score": 822.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [2, 413], "sequence": "MSKRRVVVTGLGMLSPVGNTVESTWKALLAGQSGISLIDHFDTSAYATKFAGLVKDFNCEDIISRKEQRKMDAFIQYGIVAGVQAMQDSGLEITEENATRIGAAIGSGIGGLGLIEENHTSLMNGGPRKISPFFVPSTIVNMVAGHLTIMYGLRGPSISIATACTSGVHNIGHAARIIAYGDADVMVAGGAEKASTPLGVGGFGAARALSTRNDNPQAASRPWDKERDGFVLGDGAGMLVLEEYEHAKKRGAKIYAELVGFGMSSDAYHMTSPPENGAGAALAMANALRDAGIEASQIGYVNAHGTSTPAGDKAEAQAVKTIFGEAASRVLVSSTKSMTGHLLGAAGAVESIYSILALRDQAVPPTINLDNPDEGCDLDFVPHEARQVSGMEYTLCNSFGFGGTNGSLIFKKI", "length": 413, "reference_go_mf": ["GO:0004315", "GO:0042803"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_457d89ffd266e7ef8372"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_576_1j49_assembly1", "enzyme_name": "D-lactate dehydrogenase", "ec": ["1.1.1.28"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P26297", "alignment_score": 655.0, "observed_coverage": 1.0, "aligned_identity": 0.9909638554216867, "canonical_span": [0, 332], "sequence": "MTKIFAYAIREDEKPFLKEWEDAHKDVEVEYTDKLLTPETVALAKGADGVVVYQQLDYTAETLQALADNGITKMSLRNVGVDNIDMAKAKELGFQITNVPVYSPNAIAEHAAIQAARILRQDKAMDEKVARHDLRWAPTIGREVRDQVVGVIGTGHIGQVFMQIMEGFGAKVIAYDIFRNPELEKKGYYVDSLDDLYKQADVISLHVPDVPANVHMINDESIAKMKQDVVIVNVSRGPLVDTDAVIRGLDSGKIFGYAMDVYEGEVGIFNEDWEGKEFPDARLADLIARPNVLVTPHTAFYTTHAVRNMVVKAFDNNLELVEGKEAETPVKVG", "length": 333, "reference_go_mf": ["GO:0008720", "GO:0051287"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_3d4d8aad23c7ae3c119b"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_577_1ima_assembly1", "enzyme_name": "inositol-phosphate phosphatase", "ec": ["3.1.3.25"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P29218", "alignment_score": 544.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [4, 276], "sequence": "MADPWQECMDYAVTLARQAGEVVCEAIKNEMNVMLKSSPVDLVTATDQKVEKMLISSIKEKYPSHSFIGEESVAAGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGVVYSCVEGKMYTARKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRTPETVRMVLSNMEKLFCIPVHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDVAGAGIIVTEAGGVLMDVTGGPFDLMSRRVIAANNRILAERIAKEIQVIPLQRDDED", "length": 277, "reference_go_mf": ["GO:0103026", "GO:0008877", "GO:0004346", "GO:0047954", "GO:0042802", "GO:0008934", "GO:0052832", "GO:0052833", "GO:0052834", "GO:0031403", "GO:0000287", "GO:0030145", "GO:0042803"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_8dfa317b0c2b7bd7a208"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_578_1hrk_assembly1", "enzyme_name": "ferrochelatase", "ec": ["4.99.1.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P22830", "alignment_score": 715.0, "observed_coverage": 1.0, "aligned_identity": 0.9972144846796658, "canonical_span": [64, 423], "sequence": "MRSLGANMAAALRAAGVLLRDPLASSSWRVCQPWRWKSGAAAAAVTTETAQHAQGAKPQVQPQKRKPKTGILMLNMGGPETLGDVHDFLLRLFLDRDLMTLPIQNKLAPFIAKRRTPKIQEQYRRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPHKYYIGFRYVHPLTEEAIEEMERDGLERAIAFTQYPQYSCSTTGSSLNAIYRYYNQVGRKPTMKWSTIDRWPTHHLLIQCFADHILKELDHFPLEKRSEVVILFSAHSLPMSVVNRGDPYPQEVSATVQKVMERLEYCNPYRLVWQSKVGPMPWLGPQTDESIKGLCERGRKNILLVPIAFTSDHIETLYELDIEYSQVLAKECGVENIRRAESLNGNPLFSKALADLVHSHIQSNELCSKQLTLSCPLCVNPVCRETKSFFTSQQL", "length": 423, "reference_go_mf": ["GO:0008198", "GO:0042802", "GO:0042803", "GO:0004325"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_a1f4f25ecd1db4886735"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_580_1ghs_assembly1", "enzyme_name": "glucan endo-1,3-beta-D-glucosidase", "ec": ["3.2.1.39"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P15737", "alignment_score": 612.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [28, 334], "sequence": "MARKDVASMFAAALFIGAFAAVPTSVQSIGVCYGVIGNNLPSRSDVVQLYRSKGINGMRIYFADGQALSALRNSGIGLILDIGNDQLANIAASTSNAASWVQNNVRPYYPAVNIKYIAAGNEVQGGATQSILPAMRNLNAALSAAGLGAIKVSTSIRFDEVANSFPPSAGVFKNAYMTDVARLLASTGAPLLANVYPYFAYRDNPGSISLNYATFQPGTTVRDQNNGLTYTSLFDAMVDAVYAALEKAGAPAVKVVVSESGWPSAGGFAASAGNARTYNQGLINHVGGGTPKKREALETYIFAMFNENQKTGDATERSFGLFNPDKSPAYNIQF", "length": 334, "reference_go_mf": ["GO:0042973"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_4d86d1c77f9a7f02cef4"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_581_1fgj_assembly1", "enzyme_name": "hydroxylamine oxidase", "ec": ["1.7.2.6"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q50925", "alignment_score": 992.0, "observed_coverage": 1.0, "aligned_identity": 0.9959919839679359, "canonical_span": [24, 523], "sequence": "MRIGEWMRGLLLCAGLMMCGVVHADISTVPDETYDALKLDRGKATPKETYEALVKRYKDPAHGAGKGTMGDYWEPIAISIYMDPNTFYKPPVSPKEVAERKDCVECHSDETPVWVRAWKRSTHANLDKIRNLKSDDPLYYKKGKLEEVENNLRSMGKLGEKETLKEVGCIDCHVDVNKKDKADHTKDIRMPTADTCGTCHLREFAERESERDTMVWPNGQWPAGRPSHALDYTANIETTVWAAMPQREVAEGCTMCHTNQNKCDNCHTRHEFSAAESRKPEACATCHSGVDHNNWEAYTMSKHGKLAEMNRDKWNWEVRLKDAFSKGGQNAPTCAACHMEYEGEYTHNITRKTRWANYPFVPGIAENITSDWSEARLDSWVLTCTQCHSERFARSYLDLMDKGTLEGLAKYQEANAIVHKMYEDGTLTGQKTNRPNPPEPEKPGFGIFTQLFWSKGNNPASLELKVLEMAENNLAKMHVGLAHVNPGGWTYTEGWGPMNRAYVEIQDEYTKMQELSALQARVNKLEGKQTSLLDLKGTGEKISLGGLGGGMLLAGALALIGWRKRKQTRA", "length": 570, "reference_go_mf": ["GO:0020037", "GO:0140305", "GO:0047991", "GO:0033740", "GO:0042802", "GO:0016491"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_8b3f9d2bec7c2fcdded4"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "Q50925", "alignment_score": 992.0, "observed_coverage": 1.0, "aligned_identity": 0.9959919839679359, "canonical_span": [24, 523], "sequence": "MRIGEWMRGLLLCAGLMMCGVVHADISTVPDETYDALKLDRGKATPKETYEALVKRYKDPAHGAGKGTMGDYWEPIAISIYMDPNTFYKPPVSPKEVAERKDCVECHSDETPVWVRAWKRSTHANLDKIRNLKSDDPLYYKKGKLEEVENNLRSMGKLGEKETLKEVGCIDCHVDVNKKDKADHTKDIRMPTADTCGTCHLREFAERESERDTMVWPNGQWPAGRPSHALDYTANIETTVWAAMPQREVAEGCTMCHTNQNKCDNCHTRHEFSAAESRKPEACATCHSGVDHNNWEAYTMSKHGKLAEMNRDKWNWEVRLKDAFSKGGQNAPTCAACHMEYEGEYTHNITRKTRWANYPFVPGIAENITSDWSEARLDSWVLTCTQCHSERFARSYLDLMDKGTLEGLAKYQEANAIVHKMYEDGTLTGQKTNRPNPPEPEKPGFGIFTQLFWSKGNNPASLELKVLEMAENNLAKMHVGLAHVNPGGWTYTEGWGPMNRAYVEIQDEYTKMQELSALQARVNKLEGKQTSLLDLKGTGEKISLGGLGGGMLLAGALALIGWRKRKQTRA", "length": 570, "reference_go_mf": ["GO:0020037", "GO:0140305", "GO:0047991", "GO:0033740", "GO:0042802", "GO:0016491"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_8b3f9d2bec7c2fcdded4"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_583_1lnh_assembly1", "enzyme_name": "linoleate 9S-lipoxygenase", "ec": ["1.13.11.58"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P09186", "alignment_score": 1639.0, "observed_coverage": 1.0, "aligned_identity": 0.9916267942583732, "canonical_span": [8, 857], "sequence": "MLGGLLHRGHKIKGTVVLMRKNVLHVNSVTSVGGIIGQGLDLVGSTLDTLTAFLGRPVSLQLISATKADANGKGKLGKATFLEGIITSLPTLGAGQSAFKINFEWDDGSGILGAFYIKNFMQTEFFLVSLTLEDIPNHGSIHFVCNSWIYNAKLFKSDRIFFANQTYLPSETPAPLVKYREEELHNLRGDGTGERKEWERVYDYDVYNDLGDPDKGENHARPVLGGNDTFPYPRRGRTGRKPTRKDPNSESRSNDVYLPRDEAFGHLKSSDFLTYGLKSVSQNVLPLLQSAFDLNFTPREFDSFDEVHGLYSGGIKLPTDIISKISPLPVLKEIFRTDGEQALKFPPPKVIQVSKSAWMTDEEFAREMLAGVNPNLIRCLKEFPPRSKLDSQVYGDHTSQITKEHLEPNLEGLTVDEAIQNKRLFLLGHHDPIMPYLRRINATSTKAYATRTILFLKNDGTLRPLAIELSLPHPQGDQSGAFSQVFLPADEGVESSIWLLAKAYVVVNDSCYHQLVSHWLNTHAVVEPFIIATNRHLSVVHPIYKLLHPHYRDTMNINGLARLSLVNDGGVIEQTFLWGRYSVEMSAVVYKDWVFTDQALPADLIKRGMAIEDPSCPHGIRLVIEDYPYAVDGLEIWDAIKTWVHEYVFLYYKSDDTLREDPELQACWKELVEVGHGDKKNEPWWPKMQTREELVEACAIIIWTASALHAAVNFGQYPYGGLILNRPTLSRRFMPEKGSAEYEELRKNPQKAYLKTITPKFQTLIDLSVIEILSRHASDEVYLGERDNPNWTSDTRALEAFKRFGNKLAQIENKLSERNNDEKLRNRCGPVQMPYTLLLPSSKEGLTFRGIPNSISI", "length": 857, "reference_go_mf": ["GO:0005506", "GO:1990136"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_f6828957643d763951b8"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_584_1ldm_assembly1", "enzyme_name": "L-lactate dehydrogenase", "ec": ["1.1.1.27"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00341", "alignment_score": 597.5, "observed_coverage": 1.0, "aligned_identity": 0.9513677811550152, "canonical_span": [1, 333], "sequence": "MATLKDKLIGHLATSQEPRSYNKITVVGVGAVGMACAISILMKDLADEVALVDVMEDKLKGEMMDLQHGSLFLHTAKIVSGKDYSVSAGSKLVVITAGARQQEGESRLNLVQRNVNIFKFIIPDIVKHSPDCIILVVSNPVDVLTYVAWKLSGLPMHRIIGSGCNLDSARFRYLMGERLGVHSSSCHGWVIGEHGDSSVPVWSGMNVAGVSLKELHPELGTDKDKENWKKLHKDVVDSAYEVIKLKGYTSWAIGLSVADLAETIMKNLCRVHPVSTMVKDFYGIKNDVFLSLPCVLDNHGISNIVKMKLKPDEEQQLQKSATTLWDIQKDLKF", "length": 333, "reference_go_mf": ["GO:0004459"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_e07a2bdf605343dcc09b"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_585_1lbu_assembly1", "enzyme_name": "zinc D-Ala-D-Ala carboxypeptidase", "ec": ["3.4.17.14"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00733", "alignment_score": 426.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [42, 255], "sequence": "MRPRPIRLLLTALVGAGLAFAPVSAVAAPTATASASADVGALDGCYTWSGTLSEGSSGEAVRQLQIRVAGYPGTGAQLAIDGQFGPATKAAVQRFQSAYGLAADGIAGPATFNKIYQLQDDDCTPVNFTYAELNRCNSDWSGGKVSAATARANALVTMWKLQAMRHAMGDKPITVNGGFRSVTCNSNVGGASNSRHMYGHAADLGAGSQGFCALAQAARNHGFTEILGPGYPGHNDHTHVAGGDGRFWSAPSCGI", "length": 255, "reference_go_mf": ["GO:0009046"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_ac943c8577a9c15c73ae"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_586_1lba_assembly1", "enzyme_name": "N-acetylmuramoyl-L-alanine amidase", "ec": ["3.5.1.28"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00806", "alignment_score": 290.0, "observed_coverage": 0.9931506849315068, "aligned_identity": 1.0, "canonical_span": [6, 151], "sequence": "MARVQFKQRESTDAIFVHCSATKPSQNVGVREIRQWHKEQGWLDVGYHFIIKRDGTVEAGRDEMAVGSHAKGYNHNSIGVCLVGGIDDKGKFDANFTPAQMQSLRSLLVTLLAKYEGAVLRAHHEVAPKACPSFDLKRWWEKNELVTSDRG", "length": 151, "reference_go_mf": ["GO:0008745", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_92e1a417c8fb389d83df"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_588_1kim_assembly1", "enzyme_name": "thymidine kinase", "ec": ["2.7.1.21"], "controls": [{"chain": "A", "status": "missing_reference", "selected": null, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_589_1kfu_assembly1", "enzyme_name": "calpain-2", "ec": ["3.4.22.53"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P17655", "alignment_score": 1386.0, "observed_coverage": 1.0, "aligned_identity": 0.994277539341917, "canonical_span": [1, 700], "sequence": "MAGIAAKLAKDREAAEGLGSHDRAIKYLNQDYEALRNECLEAGTLFQDPSFPAIPSALGFKELGPYSSKTRGIEWKRPTEICADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEILARVVPLNQSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALLEKAYAKINGCYEALSGGATTEGFEDFTGGIAEWYELKKPPPNLFKIIQKALQKGSLLGCSIDITSAADSEAITFQKLVKGHAYSVTGAEEVESNGSLQKLIRIRNPWGEVEWTGRWNDNCPSWNTIDPEERERLTRRHEDGEFWMSFSDFLRHYSRLEICNLTPDTLTSDTYKKWKLTKMDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDEEDGESGCTFLVGLIQKHRRRQRKMGEDMHTIGFGIYEVPEELSGQTNIHLSKNFFLTNRARERSDTFINLREVLNRFKLPPGEYILVPSTFEPNKDGDFCIRVFSEKKADYQAVDDEIEANLEEFDISEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLIIDFDNFVRCLVRLETLFKIFKQLDPENTGTIELDLISWLCFSVL", "length": 700, "reference_go_mf": ["GO:0005509", "GO:0004198", "GO:0010859", "GO:0008234", "GO:0008092", "GO:0019899", "GO:0044877"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_99722d8ab793cfe52e7f"}, "alternative_alignments": [{"accession": "P04632", "alignment_score": 81.0, "observed_coverage": 0.21888412017167383, "aligned_identity": 0.5098039215686274, "canonical_span": [101, 254], "length": 268, "reference_go_mf": ["GO:0005509", "GO:0004198"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_58_1cju_assembly1", "enzyme_name": "adenylate cyclase", "ec": ["4.6.1.1"], "controls": [{"chain": "A", "status": "reference_overlength", "selected": {"accession": "P30803", "alignment_score": 375.0, "observed_coverage": 1.0, "aligned_identity": 0.9947089947089947, "canonical_span": [457, 646], "sequence": "MSGPRSASPPGCAATRGGPEHRAAWGEAEARANGHPHAAGGATRGCSKKPGGAVTPQLQQQQQQQQHEQQHEQQQHEQQQHVQQQQRLAKRWRGDDDPPLGGDDPLAGGFGFSFRSRSAWQERGGDDCGRGSRRRRRGAAGGGSSRAPPAGGGGGPAAAGGAEVRPRSVELGLDERRGRGRAEPEPEAEAGAPGGDRGARDGDGPAGPGACCRALLQIFRSKKFPSDKLERLYQRYFFRLNQSSLTMLMAVLVLVCLVMLAFHAARPPLRLPHLAVLAAAVGVILVMAVLCNRAAFHQDHMGLACYALIAVVLAVQVVGLLLPQPRSASEGIWWTVFFIYTIYTLLPVRMRAAVLSGVLLSALHLAIALRANAQDRFLLKQLVSNVLIFSCTNIVGVCTHYPAEVSQRQAFQETRECIQARLHSQRENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEMGMDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGKAGRIHITKATLSYLNGDYEVEPGCGGERNAYLKEHSIETFLILRCTQKRKEEKAMIAKMNRQRTNSIGHNPPHWGAERPFYNHLGGNQVSKEMKRMGFEDPKDKNAQESANPEDEVDEFLGRAIDARSIDRLRSEHVRKFLLTFREPDLEKKYSKQVDDRFGAYVACASLVFLFICFVQITIVPHSVFMLSFYLTCFLLLTLVVFVSVIYSCVKLFPGPLQSLSRKIVRSKTNSTLVGVFTITLVFLSAFVNMFMCNSEDLLGCLADEHNISTSRVNACHVAASAANLSLGDEQGFCGTPWPSCNFPEYFTYSVLLSLLACSVFLQISCIGKLVLMLAIELIYVLVVEVPRVTLFDNADLLVTANAIDFNNNNGTSQCPEHATKVALKVVTPIIISVFVLALYLHAQQVESTARLDFLWKLQATEEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRVLNEIIADFDEIISEDRFRQLEKIKTIGSTYMAASGLNDSTYDKVGKTHIKALADFAMKLMDQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPDRIQVTTDMYQVLAANTYQLECRGVVKVKGKGEMMTYFLNGGPPLS", "length": 1265, "reference_go_mf": ["GO:0004016"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": [{"accession": "P26769", "alignment_score": 172.0, "observed_coverage": 0.9470899470899471, "aligned_identity": 0.6536312849162011, "canonical_span": [276, 455], "length": 1090, "reference_go_mf": ["GO:0004016", "GO:0008179", "GO:0031683", "GO:0000287", "GO:0030145"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}, {"chain": "B", "status": "reference_overlength", "selected": {"accession": "P26769", "alignment_score": 367.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [877, 1077], "sequence": "MRRRRYLRDRAEAAAAAAAGGGEGLQRSRDWLYESYYCMSQQHPLIVFLLLIVMGACLALLAVFFALGLEVEDHVAFLITVPTALAIFFAIFILVCIESVFKKLLRVFSLVIWICLVAMGYLFMCFGGTVSAWDQVSFFLFIIFVVYTMLPFNMRDAIIASILTSSSHTIVLSVYLSATPGAKEHLFWQILANVIIFICGNLAGAYHKHLMELALQQTYRDTCNCIKSRIKLEFEKRQQERLLLSLLPAHIAMEMKAEIIQRLQGPKAGQMENTNNFHNLYVKRHTNVSILYADIVGFTRLASDCSPGELVHMLNELFGKFDQIAKENECMRIKILGDCYYCVSGLPISLPNHAKNCVKMGLDMCEAIKKVRDATGVDINMRVGVHSGNVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRVHISSVTLEHLNGAYKVEEGDGEIRDPYLKQHLVKTYFVINPKGERRSPQHLFRPRHTLDGAKMRASVRMTRYLESWGAAKPFAHLHHRDSMTTENGKISTTDVPMGQHNFQNRTLRTKSQKKRFEEELNERMIQAIDGINAQKQWLKSEDIQRISLLFYNKNIEKEYRATALPAFKYYVTCACLIFLCIFIVQILVLPKTSILGFSFGAAFLSLIFILFVCFAGQLLQCSKKASTSLMWLLKSSGIIANRPWPRISLTIVTTAIILTMAVFNMFFLSNSEETTLPTANTSNANVSVPDNQASILHARNLFFLPYFIYSCILGLISCSVFLRVNYELKMLIMMVALVGYNTILLHTHAHVLDAYSQVLFQRPGIWKDLKTMGSVSLSIFFITLLVLGRQSEYYCRLDFLWKNKFKKEREEIETMENLNRVLLENVLPAHVAEHFLARSLKNEELYHQSYDCVCVMFASIPDFKEFYTESDVNKEGLECLRLLNEIIADFDDLLSKPKFSGVEKIKTIGSTYMAATGLSAIPSQEHAQEPERQYMHIGTMVEFAYALVGKLDAINKHSFNDFKLRVGINHGPVIAGVIGAQKPQYDIWGNTVNVASRMDSTGVLDKIQVTEETSLILQTLGYTCTCRGIINVKGKGDLKTYFVNTEMSRSLSQSNLAS", "length": 1090, "reference_go_mf": ["GO:0004016", "GO:0008179", "GO:0031683", "GO:0000287", "GO:0030145"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": [{"accession": "P30803", "alignment_score": 146.0, "observed_coverage": 0.9947089947089947, "aligned_identity": 0.6063829787234043, "canonical_span": [1066, 1259], "length": 1265, "reference_go_mf": ["GO:0004016"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_590_1idj_assembly1", "enzyme_name": "pectin lyase A (polysaccharide lyase 1 family)", "ec": ["4.2.2.10"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q01172", "alignment_score": 718.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [20, 379], "sequence": "MKYSTIFSAAAAVFAGSAAAVGVSGSAEGFAEGVTGGGDATPVYPDTIDELVSYLGDDEARVIVLTKTFDFTDSEGTTTGTGCAPWGTASACQVAIDQDDWCENYEPDAPSVSVEYYNAGVLGITVTSNKSLIGEGSSGAIKGKGLRIVSGAENIIIQNIAVTDINPKYVWGGDAITLDDCDLVWIDHVTTARIGRQHYVLGTSADNRVSLTNNYIDGVSDYSATCDGYHYWGIYLDGDADLVTMKGNYIYHTSGRSPKVQDNTLLHCVNNYFYDISGHAFEIGEGGYVLAEGNVFQNVDTVLETYEGAAFTVPSTTAGEVCSTYLGRDCVINGFGCSGTFSEDSTSFLSDFEGKNIASASAYTSVASRVVANAGQGNL", "length": 379, "reference_go_mf": ["GO:0030570", "GO:0047490"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_aca4bc54b469bd669b7c"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_591_1hfs_assembly1", "enzyme_name": "stromelysin 1", "ec": ["3.4.24.17"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P08254", "alignment_score": 320.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [104, 264], "sequence": "MKSLPILLLLCVAVCSAYPLDGAARGEDTSMNLVQKYLENYYDLKKDVKQFVRRKDSGPVVKKIREMQKFLGLEVTGKLDSDTLEVMRKPRCGVPDVGHFRTFPGIPKWRKTHLTYRIVNYTPDLPKDAVDSAVEKALKVWEEVTPLTFSRLYEGEADIMISFAVREHGDFYPFDGPGNVLAHAYAPGPGINGDAHFDDDEQWTKDTTGTNLFLVAAHEIGHSLGLFHSANTEALMYPLYHSLTDLTRFRLSQDDINGIQSLYGPPPDSPETPLVPTEPVPPEPGTPANCDPALSFDAVSTLRGEILIFKDRHFWRKSLRKLEPELHLISSFWPSLPSGVDAAYEVTSKDLVFIFKGNQFWAIRGNEVRAGYPRGIHTLGFPPTVRKIDAAISDKEKNKTYFFVEDKYWRFDEKRNSMEPGFPKQIAEDFPGIDSKIDAVFEEFGFFYFFTGSSQLEFDPNAKKVTHTLKSNSWLNC", "length": 477, "reference_go_mf": ["GO:0004175", "GO:0004222", "GO:0008237", "GO:0008233", "GO:0004252", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_bc389b758c19f1d32f94"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_594_1wd8_assembly1", "enzyme_name": "protein-arginine deiminase", "ec": ["3.5.3.15"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q9UM07", "alignment_score": 1000.0, "observed_coverage": 1.0, "aligned_identity": 0.9964221824686941, "canonical_span": [1, 663], "sequence": "MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP", "length": 663, "reference_go_mf": ["GO:0005509", "GO:0140794", "GO:0140797", "GO:0140795", "GO:0140798", "GO:0140796", "GO:0042802", "GO:0004668"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_ac4cb69656eeb125d95f"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_596_1eb6_assembly1", "enzyme_name": "deuterolysin", "ec": ["3.4.24.39"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P46076", "alignment_score": 354.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [175, 352], "sequence": "MRVTTLSTALFALASTAVSAPTAGSSSPGLEVKLTQIDNTRVKAVVKNTGSEEVSFVHLNFFKDAGPVKKVSIYRGQDEVQFEGIKRRLRSSGITKEAVTSLGAGETLEDEFDIASTSDLASGGPVSIRSHGFVPIVVDGKITGYIPYKSNDLTVNVDGGKAAKVTKALSQLTRRTEVTDCKGDAESSLTTALSNAAKLANQAAEAAESGDESKFEEYFKTTDQQTRTTVAERLRAVAKEAGSTSGGSTTYHCNDPYGYCEPNVLAYTLPSKNEIANCDIYYSELPPLAQKCHAQDQATTTLHEFTHAPGVYQPGTEDLGYGYDAATQLSAQDALNNADSYALYANAIELKC", "length": 352, "reference_go_mf": ["GO:0004222"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_cc92670c326e164e4563"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_597_1uch_assembly1", "enzyme_name": "ubiquitinyl hydrolase 1 (peptidase C12 type)", "ec": ["3.4.19.12"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P15374", "alignment_score": 396.5, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [4, 230], "sequence": "MEGQRWLPLEANPEVTNQFLKQLGLHPNWQFVDVYGMDPELLSMVPRPVCAVLLLFPITEKYEVFRTEEEEKIKSQGQDVTSSVYFMKQTISNACGTIGLIHAIANNKDKMHFESGSTLKKFLEESVSMSPEERARYLENYDAIRVTHETSAHEGQTEAPSIDEKVDLHFIALVHVDGHLYELDGRKPFPINHGETSDETLLEDAIEVCKKFMERDPDELRFNAIALSAA", "length": 230, "reference_go_mf": ["GO:0140757", "GO:0004843", "GO:0019784", "GO:0008233", "GO:0043130"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_3a2e230ed99300f3b9ec"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_598_1dki_assembly1", "enzyme_name": "streptopain", "ec": ["3.4.22.10"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0C0J0", "alignment_score": 564.5, "observed_coverage": 1.0, "aligned_identity": 0.9900990099009901, "canonical_span": [63, 398], "sequence": "MNKKKLGIRLLSLLALGGFVLANPVFADQNFARNEKEAKDSAITFIQKSAAIKAGARSAEDIKLDKVNLGGELSGSNMYVYNISTGGFVIVSGDKRSPEILGYSTSGSFDANGKENIASFMESYVEQIKENKKLDTTYAGTAEIKQPVVKSLLDSKGIHYNQGNPYNLLTPVIEKVKPGEQSFVGQHAATGCVATATAQIMKYHNYPNKGLKDYTYTLSSNNPYFNHPKNLFAAISTRQYNWNNILPTYSGRESNVQKMAISELMADVGISVDMDYGPSSGSAGSSRVQRALKENFGYNQSVHQINRSDFSKQDWEAQIDKELSQNQPVYYQGVGKVGGHAFVIDGADGRNFYHVNWGWGGVSDGFFRLDALNPSALGTGGGAGGFNGYQSAVVGIKP", "length": 398, "reference_go_mf": ["GO:0004197", "GO:0008234", "GO:0090729"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_0d9b86a95864ab35abe6"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_599_1fy2_assembly1", "enzyme_name": "dipeptidase E", "ec": ["3.4.13.21"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P36936", "alignment_score": 430.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 229], "sequence": "MELLLLSNSTLPGKAWLEHALPLIANQLNGRRSAVFIPFAGVTQTWDEYTDKTAEVLAPLGVNVTGIHRVADPLAAIEKAEIIIVGGGNTFQLLKESRERGLLAPMADRVKRGALYIGWSAGANLACPTIRTTNDMPIVDPNGFDALDLFPLQINPHFTNALPEGHKGETREQRIRELLVVAPELTVIGLPEGNWIQVSNGQAVLGGPNTTWVFKAGEEAVALEAGHRF", "length": 229, "reference_go_mf": ["GO:0016805", "GO:0008236"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_c6cd8a0d3ddae5d9363b"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_59_1dqs_assembly1", "enzyme_name": "3-dehydroquinate synthase", "ec": ["4.2.3.4"], "controls": [{"chain": "A", "status": "reference_overlength", "selected": {"accession": "P07547", "alignment_score": 744.0, "observed_coverage": 1.0, "aligned_identity": 0.9921259842519685, "canonical_span": [3, 391], "sequence": "MSNPTKISILGRESIIADFGLWRNYVAKDLISDCSSTTYVLVTDTNIGSIYTPSFEEAFRKAAAEITPSPRLLIYNAPPGEVSKSRQTKADIEDWMLSQNPPCGRDTVVIALGGGVIGDLTGFVASTYMRGVRYVQVPTTLLAMVDSSIGGKTAIDTPLGKNLIGAIWQPTKIYIDLEFLETLPVREFINGMAEVIKTAAISSEEEFTALEENAETILKAVRREVRPGEHRFEGIEEILKARILASARHKAYVVSADEREGGLRNLLNWGHSIGHAIEAILTPQILHGECVAIGMVKEAELARHLGILKGVAVSRIVKCLAAYGLPTSLKDARIRKLTAGKHCSVDQLMFNMALDKKNDGPKKKIVLLSAIGTPYETRASVVANEDIRVVLAPSIEVHPGVAQSSNVICAPPGSKSISNRALVLAALGSGTCRIKNLLHSDDTEVMLNALERLGAATFSWEEEGEVLVVNGKGGNLQASSSPLYLGNAGTASRFLTTVATLANSSTVDSSVLTGNNRMKQRPIGDLVDALTANGASIEYVERTGSLPLKIAASGGFAGGNINLAAKVSSQYVSSLLMCAPYAKEPVTLRLVGGKPISQPYIDMTTAMMRSFGIDVQKSTTEEHTYHIPQGRYVNPAEYVIESDASSATYPLAVAAVTGTTCTVPNIGSASLQGDARFAVEVLRPMGCTVEQTETSTTVTGPSDGILRPLPNVDMEPMTDAFLGASVLAAIARGKESNHTTRIYGIANQRVKECNRIKAMKDELAKFGVICREHDDGLEIDGIDRSNLRQPVGGVFCYDDHRVAFSFSVLSLVTPQPTLILEKECVGKTWPGWWDTLRQLFKVKLEGKELEEEPVAASGPDRANASIYIIGMRGAGKSTAGNWVSKALNRPFVDLDTELETVEGMTIPDIIKTRGWQGFRNAELEILKRTLKERSRGYVFACGGGVVEMPEARKLLTDYHKTKGNVLLLMRDIKKIMDFLSIDKTRPAYVEDMMGVWLRRKPWFQECSNIQYYSRDASPSGLARASEDFNRFLQVATGQIDSLSIIKEKEHSFFASLTLPDLREAGDILEEVCVGSDAVELRVDLLKDPASNNDIPSVDYVVEQLSFLRSRVTLPIIFTIRTQSQGGRFPDNAHDAALELYRLAFRSGCEFVDLEIAFPEDMLRAVTEMKGFSKIIASHHDPKGELSWANMSWIKFYNKALEYGDIIKLVGVARNIDDNTALRKFKNWAAEAHDVPLIAINMGDQGQLSRILNGFMTPVSHPSLPFKAAPGQLSATEIRKGLSLMGEIKPKKFAIFGSPISQSRSPALHNTLFAQVGLPHNYTRLETTNAQDVQEFIRSPDFGGASVTIPLKLDIMPLLDEVAAEAEIIGAVNTIIPVSTGKNTPSRLVGRNTDWQGMILSLRKAGVYGPKRKDQEQSALVVGGGGTARAAIYALHNMGYSPIYIVGRTPSKLENMVSTFPSSYNIRIVESPSSFESVPHVAIGTIPADQPIDPTMRETLCHMFERAQEADAEAVKAIEHAPRILLEMAYKPQVTALMRLASDSGWKTIPGLEVLVGQGWYQFKYWTGISPLYESARACSSPLI", "length": 1583, "reference_go_mf": ["GO:0003855", "GO:0003856", "GO:0003866", "GO:0005524", "GO:0046872", "GO:0004764", "GO:0004765"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}, {"chain": "B", "status": "reference_overlength", "selected": {"accession": "P07547", "alignment_score": 740.0, "observed_coverage": 1.0, "aligned_identity": 0.9921052631578947, "canonical_span": [2, 393], "sequence": "MSNPTKISILGRESIIADFGLWRNYVAKDLISDCSSTTYVLVTDTNIGSIYTPSFEEAFRKAAAEITPSPRLLIYNAPPGEVSKSRQTKADIEDWMLSQNPPCGRDTVVIALGGGVIGDLTGFVASTYMRGVRYVQVPTTLLAMVDSSIGGKTAIDTPLGKNLIGAIWQPTKIYIDLEFLETLPVREFINGMAEVIKTAAISSEEEFTALEENAETILKAVRREVRPGEHRFEGIEEILKARILASARHKAYVVSADEREGGLRNLLNWGHSIGHAIEAILTPQILHGECVAIGMVKEAELARHLGILKGVAVSRIVKCLAAYGLPTSLKDARIRKLTAGKHCSVDQLMFNMALDKKNDGPKKKIVLLSAIGTPYETRASVVANEDIRVVLAPSIEVHPGVAQSSNVICAPPGSKSISNRALVLAALGSGTCRIKNLLHSDDTEVMLNALERLGAATFSWEEEGEVLVVNGKGGNLQASSSPLYLGNAGTASRFLTTVATLANSSTVDSSVLTGNNRMKQRPIGDLVDALTANGASIEYVERTGSLPLKIAASGGFAGGNINLAAKVSSQYVSSLLMCAPYAKEPVTLRLVGGKPISQPYIDMTTAMMRSFGIDVQKSTTEEHTYHIPQGRYVNPAEYVIESDASSATYPLAVAAVTGTTCTVPNIGSASLQGDARFAVEVLRPMGCTVEQTETSTTVTGPSDGILRPLPNVDMEPMTDAFLGASVLAAIARGKESNHTTRIYGIANQRVKECNRIKAMKDELAKFGVICREHDDGLEIDGIDRSNLRQPVGGVFCYDDHRVAFSFSVLSLVTPQPTLILEKECVGKTWPGWWDTLRQLFKVKLEGKELEEEPVAASGPDRANASIYIIGMRGAGKSTAGNWVSKALNRPFVDLDTELETVEGMTIPDIIKTRGWQGFRNAELEILKRTLKERSRGYVFACGGGVVEMPEARKLLTDYHKTKGNVLLLMRDIKKIMDFLSIDKTRPAYVEDMMGVWLRRKPWFQECSNIQYYSRDASPSGLARASEDFNRFLQVATGQIDSLSIIKEKEHSFFASLTLPDLREAGDILEEVCVGSDAVELRVDLLKDPASNNDIPSVDYVVEQLSFLRSRVTLPIIFTIRTQSQGGRFPDNAHDAALELYRLAFRSGCEFVDLEIAFPEDMLRAVTEMKGFSKIIASHHDPKGELSWANMSWIKFYNKALEYGDIIKLVGVARNIDDNTALRKFKNWAAEAHDVPLIAINMGDQGQLSRILNGFMTPVSHPSLPFKAAPGQLSATEIRKGLSLMGEIKPKKFAIFGSPISQSRSPALHNTLFAQVGLPHNYTRLETTNAQDVQEFIRSPDFGGASVTIPLKLDIMPLLDEVAAEAEIIGAVNTIIPVSTGKNTPSRLVGRNTDWQGMILSLRKAGVYGPKRKDQEQSALVVGGGGTARAAIYALHNMGYSPIYIVGRTPSKLENMVSTFPSSYNIRIVESPSSFESVPHVAIGTIPADQPIDPTMRETLCHMFERAQEADAEAVKAIEHAPRILLEMAYKPQVTALMRLASDSGWKTIPGLEVLVGQGWYQFKYWTGISPLYESARACSSPLI", "length": 1583, "reference_go_mf": ["GO:0003855", "GO:0003856", "GO:0003866", "GO:0005524", "GO:0046872", "GO:0004764", "GO:0004765"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_5_1whs_assembly1", "enzyme_name": "carboxypeptidase D", "ec": ["3.4.16.6"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P08819", "alignment_score": 510.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [5, 260], "sequence": "VEPSGHAADRIARLPGQPAVDFDMYSGYITVDEGAGRSLFYLLQEAPEDAQPAPLVLWLNGGPGCSSVAYGASEELGAFRVKPRGAGLVLNEYRWNKVANVLFLDSPAGVGFSYTNTSSDIYTSGDNRTAHDSYAFLAKWFERFPHYKYRDFYIAGESYAGHYVPELSQLVHRSKNPVINLKGFMVGNGLIDDYHDYVGTFEFWWNHGIVSDDTYRRLKEACLHDSFIHPSPACDAATDVATAEQGNIDMYSLYTPVCNITSSSSSSSSSLSQQRRSRGRYPWLTGSYDPCTERYSTAYYNRRDVQMALHANVTGAMNYTWATCSDTINTHWHDAPRSMLPIYRELIAAGLRIWVFSGDTDAVVPLTATRYSIGALGLPTTTSWYPWYDDQEVGGWSQVYKGLTLVSVRGAGHEVPLHRPRQALVLFQYFLQGKPMPGQTKNAT", "length": 444, "reference_go_mf": ["GO:0004185"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_356247f5cc924ad9adcf"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P08819", "alignment_score": 306.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [286, 439], "sequence": "VEPSGHAADRIARLPGQPAVDFDMYSGYITVDEGAGRSLFYLLQEAPEDAQPAPLVLWLNGGPGCSSVAYGASEELGAFRVKPRGAGLVLNEYRWNKVANVLFLDSPAGVGFSYTNTSSDIYTSGDNRTAHDSYAFLAKWFERFPHYKYRDFYIAGESYAGHYVPELSQLVHRSKNPVINLKGFMVGNGLIDDYHDYVGTFEFWWNHGIVSDDTYRRLKEACLHDSFIHPSPACDAATDVATAEQGNIDMYSLYTPVCNITSSSSSSSSSLSQQRRSRGRYPWLTGSYDPCTERYSTAYYNRRDVQMALHANVTGAMNYTWATCSDTINTHWHDAPRSMLPIYRELIAAGLRIWVFSGDTDAVVPLTATRYSIGALGLPTTTSWYPWYDDQEVGGWSQVYKGLTLVSVRGAGHEVPLHRPRQALVLFQYFLQGKPMPGQTKNAT", "length": 444, "reference_go_mf": ["GO:0004185"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_356247f5cc924ad9adcf"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_600_1mhy_assembly1", "enzyme_name": "methane monooxygenase (soluble)", "ec": ["1.14.13.25"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P27353", "alignment_score": 1014.0, "observed_coverage": 1.0, "aligned_identity": 0.996078431372549, "canonical_span": [16, 526], "sequence": "MAISLATKAATDALKVNRAPVGVEPQEVHKWLQSFNWDFKENRTKYPTKYHMANETKEQFKVIAKEYARMEAAKDERQFGTLLDGLTRLGAGNKVHPRWGETMKVISNFLEVGEYNAIAASAMLWDSATAAEQKNGYLAQVLDEIRHTHQCAFINHYYSKHYHDPAGHNDARRTRAIGPLWKGMKRVFADGFISGDAVECSVNLQLVGEACFTNPLIVAVTEWASANGDEITPTVFLSVETDELRHMANGYQTVVSIANDPASAKFLNTDLNNAFWTQQKYFTPVLGYLFEYGSKFKVEPWVKTWNRWVYEDWGGIWIGRLGKYGVESPASLRDAKRDAYWAHHDLALAAYAMWPLGFARLALPDEEDQAWFEANYPGWADHYGKIFNEWKKLGYEDPKSGFIPYQWLLANGHDVYIDRVSQVPFIPSLAKGTGSLRVHEFNGKKHSLTDDWGERQWLIEPERYECHNVFEQYEGRELSEVIAEGHGVRSDGKTLIAQPHTRGDNLWTLEDIKRAGCVFPDPLAKF", "length": 526, "reference_go_mf": ["GO:0015049"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_07c699464215041a2ad0"}, "alternative_alignments": [{"accession": "P27355", "alignment_score": 10.0, "observed_coverage": 0.01568627450980392, "aligned_identity": 0.75, "canonical_span": [138, 146], "length": 169, "reference_go_mf": ["GO:0015049"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, {"accession": "P27354", "alignment_score": 9.0, "observed_coverage": 0.01764705882352941, "aligned_identity": 0.6666666666666666, "canonical_span": [363, 372], "length": 394, "reference_go_mf": ["GO:0015049"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_602_1kez_assembly1", "enzyme_name": "6-deoxyerythronolide-B synthase", "ec": ["2.3.1.94"], "controls": [{"chain": "A", "status": "reference_overlength", "selected": {"accession": "Q03133", "alignment_score": 534.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [2903, 3170], "sequence": "MSGDNGMTEEKLRRYLKRTVTELDSVTARLREVEHRAGEPIAIVGMACRFPGDVDSPESFWEFVSGGGDAIAEAPADRGWEPDPDARLGGMLAAAGDFDAGFFGISPREALAMDPQQRIMLEISWEALERAGHDPVSLRGSATGVFTGVGTVDYGPRPDEAPDEVLGYVGTGTASSVASGRVAYCLGLEGPAMTVDTACSSGLTALHLAMESLRRDECGLALAGGVTVMSSPGAFTEFRSQGGLAADGRCKPFSKAADGFGLAEGAGVLVLQRLSAARREGRPVLAVLAGSAVNQDGASNGLTAPSGPAQQRVIRRALENAGVRAGDVDYVEAHGTGTRLGDPIEVHALLSTYGAERDPDDPLWIGSVKSNIGHTQAAAGVAGVMKAVLALRHGEMPRTLHFDEPSPQIEWDLGAVSVVSQARSWPAGERPRRAGVSSFGISGTNAHVIVEEAPEADEPEPAPDSGPVPLVLSGRDEQAMRAQAGRLADHLAPEPRNSLRDTGFTLATRASAMEHRAVVVGDRDEALAGLRAVADRRIADRTATGQGPNSPRRVAMVFPGQGAQWQGMARDLLRESQVFADSIRDCERALAPHVDWSLTDLLSGARPLDRVDVVQPALFAVMVSLAALWRSHGVEPAAVVGHSQGEIAAAHVAGALTLEDAAKLVAVRSRVLRRLGGQGGMASFGLGTEQAAERIGRFAGALSIASVNGPRSVVVVAGESGPLDELIAECEAEAHKARRIPVDYASHSPQVESLREELLTELAGISPVSADVALYSTTTGQPIDTATMDTAYWYANLREQVRFQDATRQLAEAGFDAFVEVSPHPVLTVGIEATLDSALPADAGACVVGTLRRDRGGLADFHTALGEAYAQGVEVDWSPAFADARPVELPVYPFQRYWLPIPTGGRARDEDDDWRYQVVWREAEWESASLAGRVLLVTGPGVPSELSDAIRSGLEQSGATVLTCDVESRSTIGTALEAADTDALSTVGVAAVPHGEAVDPSLDALALVQALGAAGVEAPLWVLTRNAVQVADGELVDPAQAMVGGLGRVVGIEQPGRWGGLVDLVDADAASIRSLAAVLADPRGEEQVAIRADGIKVARLVPAPARARTHPLEPLAGTVLVTGGTGGIGAHLARWLARSGAEHLVLLGRRGADAPGASELREELTALGTGVTIAACDVADRARLEAVLAAEAAAEGRTVSAVMHAAGVSTSTPLDDLTEAEFTEIADVKVRGTVNLDELCPDLDAFVLFSSNAGVWGSPGLASYAAANAFLDGFARAARSEGAPVTSIAWGLWAGQNMAGDEGGEYLRSQGLRAMDPDRAVEELHITLDHGQTSVSVVDMDRRRFVELFTAARHRPLFDEIAGARAEARQSEEGPALAQRLAALLCDGREREHLAHLIRAEVAAVLGHGDDAAIDRDRAFRDLGFDSMTAVDLRNRLAAVTGVREAATVVFDHPTITRLADHYLERLVGAAEAEQAPALVREVPPKDADDPIAIVGMACRFPGGVHNPGELWEFIVGGGDAVTEMPTDRGWDLDALFDPDPQRHGTSYSRHGAFLDGAADFDAAFFGISPREALAMDPQQRQVLETTWELFENAGIDPHSVRGSDTGVFLGAAYQGYGQDAVVPEDSEGYLLTGNSSAVVSGRVAYVLGLEGPAVTVDTACSSSLVALHSACGSLRDGDCGLAVAGGVSVMAGPEVFTEFSRQGGLAVDGRCKAFSAEADGFGLPEGVAVVQLQRLSDGPAEGGRQVLGVVAGSAINQDGATNGLAAPSGVAQQRVIRKAWARAGITGADVAVVEAHGTGTRLGDPVEASALLATYGKSRGSSGPVLLGSVKSNIGHAQAAAGVAGVIKVVLGLNRGLVPPMLCRGERSPLIEWSSGGVELAEAVSPWPPAADGVRRAGVSAFGVSGTNAHVIIAEPPEPEPLPEPGPVGVLAAANSVPVLLSARTETALAAQARLLESAVDDSVPLTALASALATGRAHLPRRAALLAGDHEQLRGQLRAVAEGVAAPGATTGTASAGGVVFVFPGQGAQWEGMARGLLSVPVFAESIAECDAVLSEVAGFSASEVLEQRPDAPSLERVDVVQPVLFSVMVSLARLWGACGVSPSAVIGHSQGEIAAAVVAGVLSLEDGVRVVALRAKALRALAGKGGMVSLAAPGERARALIAPWEDRISVAAVNSPSSVVVSGDPEALAELVARCEDEGVRAKTLPVDYASHSRHVEEIRETILADLDGISARRAAIPLYSTLHGERRDMGPRYWYDNLRSQVRFDEAVSAQSPDGHATFVEMSPHPVLTAAVQEIAADAVAIGSLHRDTAEEHLIAELARAHVHGVAVDWRNVFPAAPPVALPNYPFEPQRYWLAPEVSDQLADSRYRVDWRPLATTPVDLEGGFLVHGSAPESLTSAVEKAGGVVPVASADREALAAALREVPGEVAGVLSVHTGAANALALHQSLGEAGVRAPLWLVTSRAVALGESEPVDPEQAMVWGLGRVMGLETPERWGGLVDLPAEPAPGDGEAFVACLGADGHEDQVAIRDHARYGRRLVRAPLGTRESSWEPAGTALVTGGTGALGGHVARHLARCGVEDLVLVSRRGVDAPAAAELEAELVALGPKTTITACDVADREQLSKLLEELRGQGRPVRTVVHTAGVPESRPLHEIGELESVCAAKVTGARLLDELCPDAETFVLFSSGAGVWGSANLGAYSAANAYLDALAHRRRAEGRAATSVAWGAWAGEGMATGDLEGLTRRGLRPMAPDRAIRALHQALDNGDTCVSIADVDWEAFAVGFTAARPRPLLDELVTPAVGAVPAVQAAPAREMTSQELLEFTHSHVAAILGHSSPDAVGQDQPFTELGFDSLTAVGLRNQLQQATGLALPATLVFEHPTVRRLADHIGQQLDSGTPAREASSALRDGYRQAGVSGRVRSYLDLLAGLSDFREHFDGSDGFSLDLVDMADGPGEVTVICCAGTAAISGPHEFTRLAGALRGIAPVRAVPQPGYEEGEPLPSSMAAVAAVQADAVIRTQGDKPFVVAGHSAGALMAYALATELLDRGHPPRGVVLIDVYPPGHQDAMNAWLEELTATLFDRETVRMDDTRLTALGAYDRLTGQWRPRETGLPTLLVSAGEPMGPWPDDSWKPTWPFEHDTVAVPGDHFTMVQEHADAIARHIDAWLGGGNS", "length": 3172, "reference_go_mf": ["GO:0004315", "GO:0047879", "GO:0004312", "GO:0031177"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_603_1jm6_assembly1", "enzyme_name": "[pyruvate dehydrogenase (acetyl-transferring)] kinase", "ec": ["2.7.11.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q64536", "alignment_score": 643.5, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [10, 374], "sequence": "MRWFRALLKNASLAGAPKYIEHFSKFSPSPLSMKQFLDFGSSNACEKTSFTFLRQELPVRLANIMKEINLLPDRVLSTPSVQLVQSWYVQSLLDIMEFLDKDPEDHRTLSQFTDALVTIRNRHNDVVPTMAQGVLEYKDTYGDDPVSNQNIQYFLDRFYLSRISIRMLINQHTLIFDGSTNPAHPKHIGSIDPNCSVSDVVKDAYDMAKLLCDKYYMASPDLEIQEVNATNATQPIHMVYVPSHLYHMLFELFKNAMRATVESHESSLTLPPIKIMVALGEEDLSIKMSDRGGGVPLRKIERLFSYMYSTAPTPQPGTGGTPLAGFGYGLPISRLYAKYFQGDLQLFSMEGFGTDAVIYLKALSTDSVERLPVYNKSAWRHYQTIQEAGDWCVPSTEPKNTSTYRVS", "length": 407, "reference_go_mf": ["GO:0005524", "GO:0042802", "GO:0042803", "GO:0004674", "GO:0044877", "GO:0004740"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_4438bf0d2129201c3b96"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_605_1q6x_assembly1", "enzyme_name": "choline O-acetyltransferase", "ec": ["2.3.1.6"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P32738", "alignment_score": 1185.0, "observed_coverage": 1.0, "aligned_identity": 0.9916666666666667, "canonical_span": [17, 617], "sequence": "MPILEKAPQKMPVKASSWEELDLPKLPVPPLQQTLATYLQCMQHLVPEEQFRKSQAIVKRFGAPGGLGETLQEKLLERQEKTANWVSEYWLNDMYLNNRLALPVNSSPAVIFARQHFQDTNDQLRFAACLISGVLSYKTLLDSHSLPTDWAKGQLSGQPLCMKQYYRLFSSYRLPGHTQDTLVAQKSSIMPEPEHVIVACCNQFFVLDVVINFRRLSEGDLFTQLRKIVKMASNEDERLPPIGLLTSDGRSEWAKARTVLLKDSTNRDSLDMIERCICLVCLDGPGTGELSDTHRALQLLHGGGCSLNGANRWYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHLLKHMMTSNKKLVRADSVSELPAPRRLRLKCSPETQGHLASSAEKLQRIVKNLDFIVYKFDNYGKTFIKKQKYSPDGFIQVALQLAYYRLYQRLVPTYESASIRRFQEGRVDNIRSATPEALAFVQAMTDHKAAMPASEKLQLLQTAMQAHKQYTVMAITGMAIDNHLLALRELARDLCKEPPEMFMDETYLMSNRFVLSTSQVPTTMEMFCCYGPVVPNGNGACYNPQPEAITFCISSFHSCKETSSVEFAEAVGASLVDMRDLCSSRQPADSKPPAPKEKARGPSQAKQS", "length": 640, "reference_go_mf": ["GO:0033265", "GO:0004102"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_fdef8e34358804671aca"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_607_1r16_assembly1", "enzyme_name": "ADP-ribosyl cyclase", "ec": ["3.2.2.6"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P29241", "alignment_score": 502.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [24, 275], "sequence": "MSPVAIIACVCLAVTLTSISPSEAIVPTRELENVFLGRCKDYEITRYLDILPRVRSDCSALWKDFFKAFSFKNPCDLDLGSYKDFFTSAQQQLPKNKVMFWSGVYDEAHDYANTGRKYITLEDTLPGYMLNSLVWCGQRANPGFNEKVCPDFKTCPVQARESFWGMASSSYAHSAEGEVTYMVDGSNPKVPAYRPDSFFGKYELPNLTNKVTRVKVIVLHRLGEKIIEKCGAGSLLDLEKLVKAKHFAFDCVENPRAVLFLLCSDNPNARECRLAKRFYRIA", "length": 282, "reference_go_mf": ["GO:0061809", "GO:0016849"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_20f65697c4a12bb5fefa"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_608_1ds2_assembly1", "enzyme_name": "streptogrisin B", "ec": ["3.4.21.81"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00777", "alignment_score": 367.0, "observed_coverage": 1.0, "aligned_identity": 0.9945945945945946, "canonical_span": [114, 299], "sequence": "MRIKRTSNRSNAARRVRTTAVLAGLAAVAALAVPTANAETPRTFSANQLTAASDAVLGADIAGTAWNIDPQSKRLVVTVDSTVSKAEINQIKKSAGANADALRIERTPGKFTKLISGGDAIYSSTGRCSLGFNVRSGSTYYFLTAGHCTDGATTWWANSARTTVLGTTSGSSFPNNDYGIVRYTNTTIPKDGTVGGQDITSAANATVGMAVTRRGSTTGTHSGSVTALNATVNYGGGDVVYGMIRTNVCAEPGDSGGPLYSGTRAIGLTSGGSGNCSSGGTTFFQPVTEALSAYGVSVY", "length": 299, "reference_go_mf": ["GO:0004252"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_017e2d2cf06135785d8a"}, "alternative_alignments": [{"accession": "P68390", "alignment_score": 9.0, "observed_coverage": 0.032432432432432434, "aligned_identity": 0.8333333333333334, "canonical_span": [70, 76], "length": 185, "reference_go_mf": ["GO:0140678", "GO:0004867"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_609_1ssx_assembly1", "enzyme_name": "alpha-lytic endopeptidase", "ec": ["3.4.21.12"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00778", "alignment_score": 396.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [199, 397], "sequence": "MYVSNHRSRRVARVSVSCLVAALAAMSCGAALAADQVDPQLKFAMQRDLGIFPTQLPQYLQTEKLARTQAAAIEREFGAQFAGSWIERNEDGSFKLVAATSGARKSSTLGGVEVRNVRYSLKQLQSAMEQLDAGANARVKGVSKPLDGVQSWYVDPRSNAVVVKVDDGATEAGVDFVALSGADSAQVRIESSPGKLQTTANIVGGIEYSINNASLCSVGFSVTRGATKGFVTAGHCGTVNATARIGGAVVGTFAARVFPGNDRAWVSLTSAQTLLPRVANGSSFVTVRGSTEAAVGAAVCRSGRTTGYQCGTITAKNVTANYAEGAVRGLTQGNACMGRGDSGGSWITSAGQAQGVMSGGNVQSNGNNCGIPASQRSSLFERLQPILSQYGLSLVTG", "length": 397, "reference_go_mf": ["GO:0004252"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_8bf257bd97719a860fa8"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_60_1dea_assembly2", "enzyme_name": "glucosamine-6-phosphate deaminase", "ec": ["3.5.99.6"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0A759", "alignment_score": 532.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 266], "sequence": "MRLIPLTTAEQVGKWAARHIVNRINAFKPTADRPFVLGLPTGGTPMTTYKALVEMHKAGQVSFKHVVTFNMDEYVGLPKEHPESYYSFMHRNFFDHVDIPAENINLLNGNAPDIDAECRQYEEKIRSYGKIHLFMGGVGNDGHIAFNEPASSLASRTRIKTLTHDTRVANSRFFDNDVNQVPKYALTVGVGTLLDAEEVMILVLGSQKALALQAAVEGCVNHMWTISCLQLHPKAIMVCDEPSTMELKVKTLRYFNELEAENIKGL", "length": 266, "reference_go_mf": ["GO:0004342", "GO:0042802"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_914386341353c57fdbd8"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_611_1ush_assembly1", "enzyme_name": "5'-nucleotidase (bacterial)", "ec": ["3.1.3.5"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P07024", "alignment_score": 1019.5, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [25, 550], "sequence": "MKLLQRGVALALLTTFTLASETALAYEQDKTYKITVLHTNDHHGHFWRNEYGEYGLAAQKTLVDGIRKEVAAEGGSVLLLSGGDINTGVPESDLQDAEPDFRGMNLVGYDAMAIGNHEFDNPLTVLRQQEKWAKFPLLSANIYQKSTGERLFKPWALFKRQDLKIAVIGLTTDDTAKIGNPEYFTDIEFRKPADEAKLVIQELQQTEKPDIIIAATHMGHYDNGEHGSNAPGDVEMARALPAGSLAMIVGGHSQDPVCMAAENKKQVDYVPGTPCKPDQQNGIWIVQAHEWGKYVGRADFEFRNGEMKMVNYQLIPVNLKKKVTWEDGKSERVLYTPEIAENQQMISLLSPFQNKGKAQLEVKIGETNGRLEGDRDKVRFVQTNMGRLILAAQMDRTGADFAVMSGGGIRDSIEAGDISYKNVLKVQPFGNVVVYADMTGKEVIDYLTAVAQMKPDSGAYPQFANVSFVAKDGKLNDLKIKGEPVDPAKTYRMATLNFNATGGDGYPRLDNKPGYVNTGFIDAEVLKAYIQKSSPLDVSVYEPKGEVSWQ", "length": 550, "reference_go_mf": ["GO:0008253", "GO:0046872", "GO:0000166", "GO:0008768"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_cf58f58b779e58f60bd7"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_612_1sll_assembly1", "enzyme_name": "anhydrosialidase", "ec": ["4.2.2.15"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q27701", "alignment_score": 1358.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [80, 759], "sequence": "MGRIGKKAMAIALVSAVMVTPLNVCATVENQEQQQVTQGAEDIAVIDDAQETVAADEAQADEAAAITVEGRETAEESSASIPEGILMEKNNVDIAEGQGYSLDQEAGAKYVKAMTQGTIILSYKSTSENGIQSLFSVGNSTAGNQDRHFHIYITNSGGIGIELRNTDGVFNYTLDRPASVRALYKGERVFNTVALKADAANKQCRLFANGELLATLDKDAFKFISDITGVDNVTLGGTKRQGKIAYPFGGTIGDIKVYSNALSDEELIQATGVTTYGENIFYAGDVTESNYFRIPSLLTLSTGTVISAADARYGGTHDSKSKINIAFAKSTDGGNTWSEPTLPLKFDDYIAKNIDWPRDSVGKNVQIQGSASYIDPVLLEDKLTKRIFLFADLMPAGIGSSNASVGSGFKEVNGKKYLKLRWHKDAGRAYDYTIREKGVIYNDATNQPTEFRVDGEYNLYQHDTNLTCKQYDYNFSGNNLIESKTDVDVNMNIFYKNSVFKAFPTNYLAMRYSDDEGASWSDLDIVSSFKPEVSKFLVVGPGIGKQISTGENAGRLLVPLYSKSSAELGFMYSDDHGDNWTYVEADNLTGGATAEAQIVEMPDGSLKTYLRTGSNCIAEVTSIDGGETWSDRVPLQGISTTSYGTQLSVINYSQPIDGKPAIILSSPNATNGRKNGKIWIGLVNDTGNTGIDKYSVEWKYSYAVDTPQMGYSYSCLAELPDGQVGLLYEKYDSWSRNELHLKDILKFEKYSISELTGQASGN", "length": 762, "reference_go_mf": ["GO:0033995", "GO:0004308"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_6ffa3de4d826c36ec898"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_613_1p1x_assembly1", "enzyme_name": "deoxyribose-phosphate aldolase", "ec": ["4.1.2.4"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0A6L0", "alignment_score": 500.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 250], "sequence": "MTDLKASSLRALKLMDLTTLNDDDTDEKVIALCHQAKTPVGNTAAICIYPRFIPIARKTLKEQGTPEIRIATVTNFPHGNDDIDIALAETRAAIAYGADEVDVVFPYRALMAGNEQVGFDLVKACKEACAAANVLLKVIIETGELKDEALIRKASEISIKAGADFIKTSTGKVAVNATPESARIMMEVIRDMGVEKTVGFKPAGGVRTAEDAQKYLAIADELFGADWADARHYRFGASSLLASLLKALGHGDGKSASSY", "length": 259, "reference_go_mf": ["GO:0004139", "GO:0016829"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_9804ca0c6e09086c5690"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_614_1q3n_assembly1", "enzyme_name": "3-deoxy-8-phosphooctulonate synthase", "ec": ["2.5.1.55"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0A715", "alignment_score": 532.5, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 284], "sequence": "MKQKVVSIGDINVANDLPFVLFGGMNVLESRDLAMRICEHYVTVTQKLGIPYVFKASFDKANRSSIHSYRGPGLEEGMKIFQELKQTFGVKIITDVHEPSQAQPVADVVDVIQLPAFLARQTDLVEAMAKTGAVINVKKPQFVSPGQMGNIVDKFKEGGNEKVILCDRGANFGYDNLVVDMLGFSIMKKVSGNSPVIFDVTHALQCRDPFGAASGGRRAQVAELARAGMAVGLAGLFIEAHPDPEHAKCDGPSALPLAKLEPFLKQMKAIDDLVKGFEELDTSK", "length": 284, "reference_go_mf": ["GO:0008676", "GO:0042802"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_30fe2efacdf4d1c61a5e"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_616_1fcq_assembly1", "enzyme_name": "hyaluronoglucosaminidase", "ec": ["3.2.1.35"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q08169", "alignment_score": 619.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [41, 362], "sequence": "MSRPLVITEGMMIGVLLMLAPINALLLGFVQSTPDNNKTVREFNVYWNVPTFMCHKYGLRFEEVSEKYGILQNWMDKFRGEEIAILYDPGMFPALLKDPNGNVVARNGGVPQLGNLTKHLQVFRDHLINQIPDKSFPGVGVIDFESWRPIFRQNWASLQPYKKLSVEVVRREHPFWDDQRVEQEAKRRFEKYGQLFMEETLKAAKRMRPAANWGYYAYPYCYNLTPNQPSAQCEATTMQENDKMSWLFESEDVLLPSVYLRWNLTSGERVGLVGGRVKEALRIARQMTTSRKKVLPYYWYKYQDRRDTDLSRADLEATLRKITDLGADGFIIWGSSDDINTKAKCLQFREYLNNELGPAVKRIALNNNANDRLTVDVSVDQV", "length": 382, "reference_go_mf": ["GO:0004415", "GO:0019863"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_a87beedaf8efda26b1eb"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_61_1bjp_assembly1", "enzyme_name": "2-hydroxymuconate tautomerase", "ec": ["5.3.2.6"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q01468", "alignment_score": 124.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 63], "sequence": "MPIAQIHILEGRSDEQKETLIREVSEAISRSLDAPLTSVRVIITEMAKGHFGIGGELASKVRR", "length": 63, "reference_go_mf": ["GO:0016853"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_df68bf0b5c3e8856c42f"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "Q01468", "alignment_score": 124.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 63], "sequence": "MPIAQIHILEGRSDEQKETLIREVSEAISRSLDAPLTSVRVIITEMAKGHFGIGGELASKVRR", "length": 63, "reference_go_mf": ["GO:0016853"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_df68bf0b5c3e8856c42f"}, "alternative_alignments": []}, {"chain": "C", "status": "assigned", "selected": {"accession": "Q01468", "alignment_score": 124.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 63], "sequence": "MPIAQIHILEGRSDEQKETLIREVSEAISRSLDAPLTSVRVIITEMAKGHFGIGGELASKVRR", "length": 63, "reference_go_mf": ["GO:0016853"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_df68bf0b5c3e8856c42f"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_621_1kyw_assembly1", "enzyme_name": "caffeate O-methyltransferase", "ec": ["2.1.1.68"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P28002", "alignment_score": 700.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [12, 362], "sequence": "MGSTGETQITPTHISDEEANLFAMQLASASVLPMILKSALELDLLEIIAKAGPGAQISPIEIASQLPTTNPDAPVMLDRMLRLLACYIILTCSVRTQQDGKVQRLYGLATVAKYLVKNEDGVSISALNLMNQDKVLMESWYHLKDAVLDGGIPFNKAYGMTAFEYHGTDPRFNKVFNKGMSDHSTITMKKILETYTGFEGLKSLVDVGGGTGAVINTIVSKYPTIKGINFDLPHVIEDAPSYPGVEHVGGDMFVSIPKADAVFMKWICHDWSDEHCLKFLKNCYEALPDNGKVIVAECILPVAPDSSLATKGVVHIDVIMLAHNPGGKERTQKEFEDLAKGAGFQGFKVHCNAFNTYIMEFLKKV", "length": 365, "reference_go_mf": ["GO:0047763", "GO:0046983", "GO:0008757"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_ee6be28e4dd036e24ead"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_623_1r1j_assembly1", "enzyme_name": "neprilysin", "ec": ["3.4.24.11"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P08473", "alignment_score": 1392.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [54, 750], "sequence": "MGKSESQMDITDINTPKPKKKQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW", "length": 750, "reference_go_mf": ["GO:1901612", "GO:0004175", "GO:0008238", "GO:0004181", "GO:0004222", "GO:0070012", "GO:0042277", "GO:0001786", "GO:0042803", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_1a916537b7b555892eb6"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_624_1gcb_assembly1", "enzyme_name": "bleomycin hydrolase", "ec": ["3.4.22.40"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q01532", "alignment_score": 904.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [30, 482], "sequence": "MLPTSVSRSLYLKTFRSHLLRAPQIVLKRMSSSIDISKINSWNKEFQSDLTHQLATTVLKNYNADDALLNKTRLQKQDNRVFNTVVSTDSTPVTNQKSSGRCWLFAATNQLRLNVLSELNLKEFELSQAYLFFYDKLEKANYFLDQIVSSADQDIDSRLVQYLLAAPTEDGGQYSMFLNLVKKYGLIPKDLYGDLPYSTTASRKWNSLLTTKLREFAETLRTALKERSADDSIIVTLREQMQREIFRLMSLFMDIPPVQPNEQFTWEYVDKDKKIHTIKSTPLEFASKYAKLDPSTPVSLINDPRHPYGKLIKIDRLGNVLGGDAVIYLNVDNETLSKLVVKRLQNNKAVFFGSHTPKFMDKKTGVMDIELWNYPAIGYNLPQQKASRIRYHESLMTHAMLITGCHVDETSKLPLRYRVENSWGKDSGKDGLYVMTQKYFEEYCFQIVVDINELPKELASKFTSGKEEPIVLPIWDPMGALAK", "length": 483, "reference_go_mf": ["GO:0004177", "GO:0070005", "GO:0004197", "GO:0008234", "GO:0003690", "GO:0003729", "GO:0000978", "GO:0003697"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_66f8f84db1edfd2fffd3"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_625_1ltq_assembly1", "enzyme_name": "polynucleotide 5'-hydroxyl-kinase", "ec": ["2.7.1.78"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P06855", "alignment_score": 499.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 301], "sequence": "MKKIILTIGCPGSGKSTWAREFIAKNPGFYNINRDDYRQSIMAHEERDEYKYTKKKEGIVTGMQFDTAKSILYGGDSVKGVIISDTNLNPERRLAWETFAKEYGWKVEHKVFDVPWTELVKRNSKRGTKAVPIDVLRSMYKSMREYLGLPVYNGTPGKPKAVIFDVDGTLAKMNGRGPYDLEKCDTDVINPMVVELSKMYALMGYQIVVVSGRESGTKEDPTKYYRMTRKWVEDIAGVPLVMQCQREQGDTRKDDVVKEEIFWKHIAPHFDVKLAIDDRTQVVEMWRRIGVECWQVASGDF", "length": 301, "reference_go_mf": ["GO:0005524", "GO:0046404", "GO:0047846"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_0f158febb772bfcbd528"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_626_1epw_assembly1", "enzyme_name": "bontoxilysin", "ec": ["3.4.24.69"], "controls": [{"chain": "A", "status": "reference_overlength", "selected": {"accession": "P10844", "alignment_score": 2567.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 1291], "sequence": "MPVTINNFNYNDPIDNNNIIMMEPPFARGTGRYYKAFKITDRIWIIPERYTFGYKPEDFNKSSGIFNRDVCEYYDPDYLNTNDKKNIFLQTMIKLFNRIKSKPLGEKLLEMIINGIPYLGDRRVPLEEFNTNIASVTVNKLISNPGEVERKKGIFANLIIFGPGPVLNENETIDIGIQNHFASREGFGGIMQMKFCPEYVSVFNNVQENKGASIFNRRGYFSDPALILMHELIHVLHGLYGIKVDDLPIVPNEKKFFMQSTDAIQAEELYTFGGQDPSIITPSTDKSIYDKVLQNFRGIVDRLNKVLVCISDPNININIYKNKFKDKYKFVEDSEGKYSIDVESFDKLYKSLMFGFTETNIAENYKIKTRASYFSDSLPPVKIKNLLDNEIYTIEEGFNISDKDMEKEYRGQNKAINKQAYEEISKEHLAVYKIQMCKSVKAPGICIDVDNEDLFFIADKNSFSDDLSKNERIEYNTQSNYIENDFPINELILDTDLISKIELPSENTESLTDFNVDVPVYEKQPAIKKIFTDENTIFQYLYSQTFPLDIRDISLTSSFDDALLFSNKVYSFFSMDYIKTANKVVEAGLFAGWVKQIVNDFVIEANKSNTMDKIADISLIVPYIGLALNVGNETAKGNFENAFEIAGASILLEFIPELLIPVVGAFLLESYIDNKNKIIKTIDNALTKRNEKWSDMYGLIVAQWLSTVNTQFYTIKEGMYKALNYQAQALEEIIKYRYNIYSEKEKSNINIDFNDINSKLNEGINQAIDNINNFINGCSVSYLMKKMIPLAVEKLLDFDNTLKKNLLNYIDENKLYLIGSAEYEKSKVNKYLKTIMPFDLSIYTNDTILIEMFNKYNSEILNNIILNLRYKDNNLIDLSGYGAKVEVYDGVELNDKNQFKLTSSANSKIRVTQNQNIIFNSVFLDFSVSFWIRIPKYKNDGIQNYIHNEYTIINCMKNNSGWKISIRGNRIIWTLIDINGKTKSVFFEYNIREDISEYINRWFFVTITNNLNNAKIYINGKLESNTDIKDIREVIANGEIIFKLDGDIDRTQFIWMKYFSIFNTELSQSNIEERYKIQSYSEYLKDFWGNPLMYNKEYYMFNAGNKNSYIKLKKDSPVGEILTRSKYNQNSKYINYRDLYIGEKFIIRRKSNSQSINDDIVRKEDYIYLDFFNLNQEWRVYTYKYFKKEEEKLFLAPISDSDEFYNTIQIKEYDEQPTYSCQLLFKKDEESTDEIGLIGIHRFYESGIVFEEYKDYFCISKWYLKEVKRKPYNLKLGCNWQFIPKDEGWTE", "length": 1291, "reference_go_mf": ["GO:0004222", "GO:0008320", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_627_1l6p_assembly1", "enzyme_name": "protein-disulfide reductase", "ec": ["1.8.1.8"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P36655", "alignment_score": 242.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [22, 143], "sequence": "MAQRIFTLILLLCSTSVFAGLFDAPGRSQFVPADQAFAFDFQQNQHDLNLTWQIKDGYYLYRKQIRITPEHAKIADVQLPQGVWHEDEFYGKSEIYRDRLTLPVTINQASAGATLTVTYQGCADAGFCYPPETKTVPLSEVVANNAAPQPVSVPQQEQPTAQLPFSALWALLIGIGIAFTPCVLPMYPLISGIVLGGKQRLSTARALLLTFIYVQGMALTYTALGLVVAAAGLQFQAALQHPYVLIGLAIVFTLLAMSMFGLFTLQLPSSLQTRLTLMSNRQQGGSPGGVFVMGAIAGLICSPCTTAPLSAILLYIAQSGNMWLGGGTLYLYALGMGLPLMLITVFGNRLLPKSGPWMEQVKTAFGFVILALPVFLLERVIGDVWGLRLWSALGVAFFGWAFITSLQAKRGWMRIVQIILLAAALVSVRPLQDWAFGATHTAQTQTHLNFTQIKTVDELNQALVEAKGKPVMLDLYADWCVACKEFEKYTFSDPQVQKALADTVLLQANVTANDAQDVALLKHLNVLGLPTILFFDGQGQEHPQARVTGFMDAETFSAHLRDRQP", "length": 565, "reference_go_mf": ["GO:0009055", "GO:0047134", "GO:0015035"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_7ff9fc9e609b613a2893"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_629_1ndi_assembly1", "enzyme_name": "carnitine O-acetyltransferase", "ec": ["2.3.1.7"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P47934", "alignment_score": 1192.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [29, 625], "sequence": "MLAFAARTVVKPLGLLKPSSLMKVSGRFKAHQDALPRLPVPPLQQSLDYYLKALQPIVSEEEWAHTKQLVDEFQTSGGVGERLQKGLERRAKKMENWLSEWWLKTAYLQFRQPVVIYSSPGVILPKQDFVDLQGQLRFAAKLIEGVLDFKSMIDNETLPVEFLGGQPLCMNQYYQILSSCRVPGPKQDSVVNFLKSKRPPTHITVVHNYQFFELDVYHSDGTPLTSDQIFVQLEKIWNSSLQSNKEPVGILTSNHRNTWAKAYNNLIKDKVNRESVNSIQKSIFTVCLDKQVPRVSDDVYRNHVAGQMLHGGGSKFNSGNRWFDKTLQFIVAEDGSCGMVYEHAAAEGPPIVALVDHVMEYTKKPELVRSPMVPLPMPKKLRFNITPEIKNDIEKAKQNLSIMIQDLDIMMLTFHHFGKDFPKSEKLSPDAFIQVALQLAYYRIYGQACATYESASLRMFHLGRTDTIRSASIDSLAFVKGMGDSTVPEQQKVELLRKAVQAHRAYTDRAIRGEAFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIAMHFNLSTSQVPAKTDCVMFFGPVVPDGYGICYNPMEAHINFSVSAYNSCAETNAARMAHYLEKALLDMRTLLQNHPRAKL", "length": 626, "reference_go_mf": ["GO:0003997", "GO:0004092", "GO:0008458"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_3fb7c97166e66dc463a7"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_62_1req_assembly1", "enzyme_name": "methylmalonyl-CoA mutase", "ec": ["5.4.99.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P11653", "alignment_score": 1454.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 728], "sequence": "MSTLPRFDSVDLGNAPVPADAARRFEELAAKAGTGEAWETAEQIPVGTLFNEDVYKDMDWLDTYAGIPPFVHGPYATMYAFRPWTIRQYAGFSTAKESNAFYRRNLAAGQKGLSVAFDLPTHRGYDSDNPRVAGDVGMAGVAIDSIYDMRELFAGIPLDQMSVSMTMNGAVLPILALYVVTAEEQGVKPEQLAGTIQNDILKEFMVRNTYIYPPQPSMRIISEIFAYTSANMPKWNSISISGYHMQEAGATADIEMAYTLADGVDYIRAGESVGLNVDQFAPRLSFFWGIGMNFFMEVAKLRAARMLWAKLVHQFGPKNPKSMSLRTHSQTSGWSLTAQDVYNNVVRTCIEAMAATQGHTQSLHTNSLDEAIALPTDFSARIARNTQLFLQQESGTTRVIDPWSGSAYVEELTWDLARKAWGHIQEVEKVGGMAKAIEKGIPKMRIEEAAARTQARIDSGRQPLIGVNKYRLEHEPPLDVLKVDNSTVLAEQKAKLVKLRAERDPEKVKAALDKITWAAGNPDDKDPDRNLLKLCIDAGRAMATVGEMSDALEKVFGRYTAQIRTISGVYSKEVKNTPEVEEARELVEEFEQAEGRRPRILLAKMGQDGHDRGQKVIATAYADLGFDVDVGPLFQTPEETARQAVEADVHVVGVSSLAGGHLTLVPALRKELDKLGRPDILITVGGVIPEQDFDELRKDGAVEIYTPGTVIPESAISLVKKLRASLDA", "length": 728, "reference_go_mf": ["GO:0031419", "GO:0046872", "GO:0004494"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_dc0c1566b09a8f4eec28"}, "alternative_alignments": [{"accession": "P11652", "alignment_score": 45.0, "observed_coverage": 0.08253094910591471, "aligned_identity": 0.5833333333333334, "canonical_span": [372, 432], "length": 638, "reference_go_mf": ["GO:0031419", "GO:0046872", "GO:0004494"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_631_1agy_assembly1", "enzyme_name": "cutinase", "ec": ["3.1.1.74"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00590", "alignment_score": 394.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [32, 229], "sequence": "MKFFALTTLLAATASALPTSNPAQELEARQLGRTTRDDLINGNSASCRDVIFIYARGSTETGNLGTLGPSIASNLESAFGKDGVWIQGVGGAYRATLGDNALPRGTSSAAIREMLGLFQQANTKCPDATLIAGGYSQGAALAAASIEDLDSAIRDKIAGTVLFGYTKNLQNRGRIPNYPADRTKVFCNTGDLVCTGSLIVAAPHLAYGPDARGPAPEFLIEKVRAVRGSA", "length": 230, "reference_go_mf": ["GO:0050525"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_42bcb00678451cbf30f5"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_632_1jms_assembly1", "enzyme_name": "DNA nucleotidylexotransferase", "ec": ["2.7.7.31"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P09838", "alignment_score": 713.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [147, 510], "sequence": "MDPLQAVHLGPRKKRPRQLGTPVASTPYDIRFRDLVLFILEKKMGTTRRAFLMELARRKGFRVENELSDSVTHIVAENNSGSDVLEWLQLQNIKASSELELLDISWLIECMGAGKPVEMMGRHQLVVNRNSSPSPVPGSQNVPAPAVKKISQYACQRRTTLNNYNQLFTDALDILAENDELRENEGSCLAFMRASSVLKSLPFPITSMKDTEGIPCLGDKVKSIIEGIIEDGESSEAKAVLNDERYKSFKLFTSVFGVGLKTAEKWFRMGFRTLSKIQSDKSLRFTQMQKAGFLYYEDLVSCVNRPEAEAVSMLVKEAVVTFLPDALVTMTGGFRRGKMTGHDVDFLITSPEATEDEEQQLLHKVTDFWKQQGLLLYCDILESTFEKFKQPSRKVDALDHFQKCFLILKLDHGRVHSEKSGQQEGKGWKAIRVDLVMCPYDRRAFALLGWTGSRQFERDLRRYATHERKMMLDNHALYDRTKRVFLEAESEEEIFAHLGLDYIEPWERNA", "length": 510, "reference_go_mf": ["GO:0003677", "GO:0003912", "GO:0034061", "GO:0003887"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_0f569356165b4cdb02e1"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_633_1aug_assembly1", "enzyme_name": "pyroglutamyl-peptidase I", "ec": ["3.4.19.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P46107", "alignment_score": 420.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 210], "sequence": "MEKKVLLTGFDPFGGETVNPSWEAVKRLNGAAEGPASIVSEQVPTVFYKSLAVLREAIKKHQPDIIICVGQAGGRMQITPERVAINLNEARIPDNEGNQPVGEDISQGGPAAYWTGLPIKRIVEEIKKEGIPAAVSYTAGTFVCNHLFYGLMDEISRHHPHIRGGFIHIPYIPEQTLQKSAPSLSLDHITKALKIAAVTAAVHEDDIETGGGELH", "length": 215, "reference_go_mf": ["GO:0016920"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_d9b83d0602d10adeeb58"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_634_1v0y_assembly1", "enzyme_name": "phospholipase D", "ec": ["3.1.4.4"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P84147", "alignment_score": 969.5, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [2, 506], "sequence": "ADSATPHLDAVEQTLRQVSPGLEGDVWERTSGNKLDGSAADPSDWLLQTPGCWGDDKCADRVGTKRLLAKMTENIGNATRTVDISTLAPFPNGAFQDAIVAGLKESAAKGNKLKVRILVGAAPVYHMNVIPSKYRDELTAKLGKAAENITLNVASMTTSKTAFSWNHSKILVVDGQSALTGGINSWKDDYLDTTHPVSDVDLALTGPAAGSAGRYLDTLWTWTCQNKSNIASVWFAASGNAGCMPTMHKDTNPKASPATGNVPVIAVGGLGVGIKDVDPKSTFRPDLPTASDTKCVVGLHDNTNADRDYDTVNPEESALRALVASAKGHIEISQQDLNATCPPLPRYDIRLYDALAAKMAAGVKVRIVVSDPANRGAVGSGGYSQIKSLSEISDTLRNRLANITGGQQAAKTAMCSNLQLATFRSSPNGKWADGHPYAQHHKLVSVDSSTFYIGSKNLYPSWLQDFGYIVESPEAAKQLDAKLLDPQWKYSQETATVDYARGICNA", "length": 506, "reference_go_mf": ["GO:0004630", "GO:0030572"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_506bd23b48adb857aef4"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_635_1t7d_assembly1", "enzyme_name": "signal peptidase I", "ec": ["3.4.21.89"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00803", "alignment_score": 424.5, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [80, 324], "sequence": "MANMFALILVIATLVTGILWCVDKFFFAPKRRERQAAAQAAAGDSLDKATLKKVAPKPGWLETGASVFPVLAIVLIVRSFIYEPFQIPSGSMMPTLLIGDFILVEKFAYGIKDPIYQKTLIETGHPKRGDIVVFKYPEDPKLDYIKRAVGLPGDKVTYDPVSKELTIQPGCSSGQACENALPVTYSNVEPSDFVQTFSRRNGGEATSGFFEVPKNETKENGIRLSERKETLGDVTHRILTVPIAQDQVGMYYQQPGQQLATWIVPPGQYFMMGDNRDNSADSRYWGFVPEANLVGRATAIWMSFDKQEGEWPTGLRLSRIGGIH", "length": 324, "reference_go_mf": ["GO:0004175", "GO:0008233", "GO:0004252", "GO:0009003"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_0fdccc9cc749eb006122"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_636_1uaq_assembly1", "enzyme_name": "cytosine deaminase (yeast)", "ec": ["3.5.4.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q12178", "alignment_score": 302.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [7, 158], "sequence": "MVTGGMASKWDQKGMDIAYEEAALGYKEGGVPIGGCLINNKDGSVLGRGHNMRFQKGSATLHGEISTLENCGRLEGKVYKDTTLYTTLSPCDMCTGAIIMYGIPRCVVGENVNFKSKGEKYLQTRGHEVVVVDDERCKKIMKQFIDERPQDWFEDIGE", "length": 158, "reference_go_mf": ["GO:0004131", "GO:0008835", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_07116e31b984b01799a7"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_637_1dek_assembly1", "enzyme_name": "(deoxy)nucleoside-phosphate kinase", "ec": ["2.7.4.13"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P04531", "alignment_score": 474.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 241], "sequence": "MKLIFLSGVKRSGKDTTADFIMSNYSAVKYQLAGPIKDALAYAWGVFAANTDYPCLTRKEFEGIDYDRETNLNLTKLEVITIMEQAFCYLNGKSPIKGVFVFDDEGKESVNFVAFNKITDVINNIEDQWSVRRLMQALGTDLIVNNFDRMYWVKLFALDYLDKFNSGYDYYIVPDTRQDHEMDAARAMGATVIHVVRPGQKSNDTHITEAGLPIRDGDLVITNDGSLEELFSKIKNTLKVL", "length": 241, "reference_go_mf": ["GO:0005524", "GO:0047507", "GO:0050316", "GO:0004798", "GO:0046872"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_d20ea8577940413b8d0e"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_638_1i1i_assembly1", "enzyme_name": "neurolysin", "ec": ["3.4.24.16"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P42676", "alignment_score": 1330.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [36, 701], "sequence": "MITLCLSTLRGLHRAGGSRLQLTMTLGKELASPLQAMSSYTAAGRNVLRWDLSPEQIKTRTEQLIAQTKQVYDTVGTIALKEVTYENCLQVLADIEVTYIVERTMLDFPQHVSSDREVRAASTEADKKLSRFDIEMSMREDVFQRIVHLQETCDLEKIKPEARRYLEKSIKMGKRNGLHLSEHIRNEIKSMKKRMSELCIDFNKNLNEDDTSLVFSKAELGALPDDFIDSLEKTDEDKYKVTLKYPHYFPVMKKCCVPETRRKMEMAFHTRCKQENTAILQQLLPLRAQVAKLLGYNTHADFVLELNTAKSTSRVAAFLDDLSQKLKPLGEAEREFILSLKKKECEERGFEYDGKINAWDLHYYMTQTEELKYSVDQESLKEYFPIEVVTEGLLSIYQELLGLSFEQVPDAHVWNKSVSLYTVKDKATGEVLGQFYLDLYPREGKYNHAACFGLQPGCLLPDGSRMMSVAALVVNFSQPVAGRPSLLRHDEVRTYFHEFGHVMHQICAQTDFARFSGTNVETDFVEVPSQMLENWVWDVDSLRKLSKHYKDGHPITDELLEKLVASRLVNTGLLTLRQIVLSKVDQSLHTNATLDAASEYAKYCTEILGVAATPGTNMPATFGHLAGGYDGQYYGYLWSEVFSMDMFHSCFKKEGIMNPEVGMKYRNLILKPGGSLDGMDMLQNFLQREPNQKAFLMSRGLNGS", "length": 704, "reference_go_mf": ["GO:0004175", "GO:0004222", "GO:0070012", "GO:0008233", "GO:0042277"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_8f60a90eb8e59b7da79c"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_63_1cb7_assembly1", "enzyme_name": "methylaspartate mutase", "ec": ["5.4.99.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P80078", "alignment_score": 268.0, "observed_coverage": 1.0, "aligned_identity": 0.9854014598540146, "canonical_span": [0, 137], "sequence": "MEKKTIVLGVIGSDCHAVGNKILDHAFTNAGFNVVNIGVLSPQEVFIKAAIETKADAILLSSLYGQGEIDCKGLRQKCDEAGLEGILLYVGGNIVVGKQHWPDVEKRFKDMGYDRVYAPGTPPEVGIADLKKDLNIE", "length": 137, "reference_go_mf": ["GO:0031419", "GO:0046872", "GO:0050097"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_6437d2a2403efde135c2"}, "alternative_alignments": [{"accession": "P80077", "alignment_score": 9.0, "observed_coverage": 0.06569343065693431, "aligned_identity": 0.6666666666666666, "canonical_span": [123, 132], "length": 483, "reference_go_mf": ["GO:0031419", "GO:0050097"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}, {"chain": "B", "status": "assigned", "selected": {"accession": "P80077", "alignment_score": 963.0, "observed_coverage": 1.0, "aligned_identity": 0.9979296066252588, "canonical_span": [0, 483], "sequence": "MELKNKKWTDEEFHKQREEVLQQWPTGKEVDLQEAVDYLKKIPAEKNFAEKLVLAKKKGITMAQPRAGVALLDEHIELLRYLQDEGGADFLPSTIDAYTRQNRYDECENGIKESEKAGRSLLNGFPGVNYGVKGCRKVLEAVNLPLQARHGTPDSRLLAEIIHAGGWTSNEGGGISYNVPYAKNVTIEKSLLDWQYCDRLVGFYEEQGVHINREPFGPLTGTLVPPSMSNAVGITEALLAAEQGVKNITVGYGECGNMIQDIAALRCLEEQTNEYLKAYGYNDVFVTTVFHQWMGGFPQDESKAFGVIVTATTIAALAGATKVIVKTPHEAIGIPTKEANAAGIKATKMALNMLEGQRMPMSKELETEMAVIKAETKCILDKMFELGKGDLAIGTVKAFETGVMDIPFGPSKYNAGKMMPVRDNLGCVRYLEFGNVPFTEEIKNYNRERLQERAKFEGRDVSFQMVIDDIFAVGKGRLIGRPE", "length": 483, "reference_go_mf": ["GO:0031419", "GO:0050097"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_6f1c4422f26c3cb1a361"}, "alternative_alignments": [{"accession": "P80078", "alignment_score": 9.0, "observed_coverage": 0.018633540372670808, "aligned_identity": 0.6666666666666666, "canonical_span": [30, 39], "length": 137, "reference_go_mf": ["GO:0031419", "GO:0046872", "GO:0050097"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_640_1l8t_assembly1", "enzyme_name": "kanamycin kinase", "ec": ["2.7.1.95"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0A3Y5", "alignment_score": 526.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 264], "sequence": "MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLKMTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEYEDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWEEDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKWYDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF", "length": 264, "reference_go_mf": ["GO:0005524", "GO:0008910"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_9104b10221dc127a1d17"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_641_1pwv_assembly1", "enzyme_name": "anthrax lethal factor endopeptidase", "ec": ["3.4.24.83"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P15917", "alignment_score": 1449.0, "observed_coverage": 1.0, "aligned_identity": 0.9986357435197817, "canonical_span": [59, 809], "sequence": "MNIKKEFIKVISMSCLVTAITLSGPVFIPLVQGAGGHGDVGMHVKEKEKNKDENKRKDEERNKTQEEHLKEIMKHIVKIEVKGEEAVKKEAAEKLLEKVPSDVLEMYKAIGGKIYIVDGDITKHISLEALSEDKKKIKDIYGKDALLHEHYVYAKEGYEPVLVIQSSEDYVENTEKALNVYYEIGKILSRDILSKINQPYQKFLDVLNTIKNASDSDGQDLLFTNQLKEHPTDFSVEFLEQNSNEVQEVFAKAFAYYIEPQHRDVLQLYAPEAFNYMDKFNEQEINLSLEELKDQRMLARYEKWEKIKQHYQHWSDSLSEEGRGLLKKLQIPIEPKKDDIIHSLSQEEKELLKRIQIDSSDFLSTEEKEFLKKLQIDIRDSLSEEEKELLNRIQVDSSNPLSEKEKEFLKKLKLDIQPYDINQRLQDTGGLIDSPSINLDVRKQYKRDIQNIDALLHQSIGSTLYNKIYLYENMNINNLTATLGADLVDSTDNTKINRGIFNEFKKNFKYSISSNYMIVDINERPALDNERLKWRIQLSPDTRAGYLENGKLILQRNIGLEIKDVQIIKQSEKEYIRIDAKVVPKSKIDTKIQEAQLNINQEWNKALGLPKYTKLITFNVHNRYASNIVESAYLILNEWKNNIQSDLIKKVTNYLVDGNGRFVFTDITLPNIAEQYTHQDEIYEQVHSKGLYVPESRSILLHGPSKGVELRNDSEGFIHEFGHAVDDYAGYLLDKNQSDLVTNSKKFIDIFKEEGSNLTSYGRTNEAEFFAEAFRLMHSTDHAERLKVQKNAPKTFQFINDQIKFIINS", "length": 809, "reference_go_mf": ["GO:0004222", "GO:0008237", "GO:0090729", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_0f08a0f33648783b36fa"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_642_1nsf_assembly1", "enzyme_name": "vesicle-fusing ATPase", "ec": ["3.6.4.6"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P18708", "alignment_score": 494.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [488, 735], "sequence": "MAGRSMQAARCPTDELSLSNCAVVSEKDYQSGQHVIVRTSPNHKYIFTLRTHPSVVPGSVAFSLPQRKWAGLSIGQEIEVALYSFDKAKQCIGTMTIEIDFLQKKNIDSNPYDTDKMAAEFIQQFNNQAFSVGQQLVFSFNDKLFGLLVKDIEAMDPSILKGEPASGKRQKIEVGLVVGNSQVAFEKAENSSLNLIGKAKTKENRQSIINPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIKASTKVEVDMEKAESLQVTRGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGASPLDFD", "length": 744, "reference_go_mf": ["GO:0005524", "GO:0016887", "GO:0140545", "GO:0042802", "GO:0035255", "GO:0030165", "GO:0019901", "GO:0044877", "GO:0000149"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_0727e4f6019b0d9f2008"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P18708", "alignment_score": 494.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [488, 735], "sequence": "MAGRSMQAARCPTDELSLSNCAVVSEKDYQSGQHVIVRTSPNHKYIFTLRTHPSVVPGSVAFSLPQRKWAGLSIGQEIEVALYSFDKAKQCIGTMTIEIDFLQKKNIDSNPYDTDKMAAEFIQQFNNQAFSVGQQLVFSFNDKLFGLLVKDIEAMDPSILKGEPASGKRQKIEVGLVVGNSQVAFEKAENSSLNLIGKAKTKENRQSIINPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIKASTKVEVDMEKAESLQVTRGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGASPLDFD", "length": 744, "reference_go_mf": ["GO:0005524", "GO:0016887", "GO:0140545", "GO:0042802", "GO:0035255", "GO:0030165", "GO:0019901", "GO:0044877", "GO:0000149"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_0727e4f6019b0d9f2008"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_643_1g99_assembly1", "enzyme_name": "acetate kinase", "ec": ["2.7.2.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P38502", "alignment_score": 796.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 398], "sequence": "MKVLVINAGSSSLKYQLIDMTNESALAVGLCERIGIDNSIITQKKFDGKKLEKLTDLPTHKDALEEVVKALTDDEFGVIKDMGEINAVGHRVVHGGEKFTTSALYDEGVEKAIKDCFELAPLHNPPNMMGISACAEIMPGTPMVIVFDTAFHQTMPPYAYMYALPYDLYEKHGVRKYGFHGTSHKYVAERAALMLGKPAEETKIITCHLGNGSSITAVEGGKSVETSMGFTPLEGLAMGTRCGSIDPAIVPFLMEKEGLTTREIDTLMNKKSGVLGVSGLSNDFRDLDEAASKGNRKAELALEIFAYKVKKFIGEYSAVLNGADAVVFTAGIGENSASIRKRILTGLDGIGIKIDDEKNKIRGQEIDISTPDAKVRVFVIPTNEELAIARETKEIVETEVKLRSSIPV", "length": 408, "reference_go_mf": ["GO:0008776", "GO:0000287"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_0badd626903d8a669af1"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_644_1nww_assembly1", "enzyme_name": "limonene-1,2-epoxide hydrolase", "ec": ["3.3.2.8"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q9ZAG3", "alignment_score": 290.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [4, 149], "sequence": "MTSKIEQPRWASKDSAAGAASTPDEKIVLEFMDALTSNDAAKLIEYFAEDTMYQNMPLPPAYGRDAVEQTLAGLFTVMSIDAVETFHIGSSNGLVYTERVDVLRALPTGKSYNLSILGVFQLTEGKITGWRDYFDLREFEEAVDLPLRG", "length": 149, "reference_go_mf": ["GO:0018744"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_a6cec520e1351c1b2bd8"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_645_1gt7_assembly1", "enzyme_name": "rhamnulose-1-phosphate aldolase", "ec": ["4.1.2.19"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P32169", "alignment_score": 548.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 274], "sequence": "MQNITQSWFVQGMIKATTDAWLKGWDERNGGNLTLRLDDADIAPYHDNFHQQPRYIPLSQPMPLLANTPFIVTGSGKFFRNVQLDPAANLGIVKVDSDGAGYHILWGLTNEAVPTSELPAHFLSHCERIKATNGKDRVIMHCHATNLIALTYVLENDTAVFTRQLWEGSTECLVVFPDGVGILPWMVPGTDEIGQATAQEMQKHSLVLWPFHGVFGSGPTLDETFGLIDTAEKSAQVLVKVYSMGGMKQTISREELIALGKRFGVTPLASALAL", "length": 274, "reference_go_mf": ["GO:0016832", "GO:0042802", "GO:0008994"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_b81b8b4b1e5a8e8190bf"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P32169", "alignment_score": 548.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 274], "sequence": "MQNITQSWFVQGMIKATTDAWLKGWDERNGGNLTLRLDDADIAPYHDNFHQQPRYIPLSQPMPLLANTPFIVTGSGKFFRNVQLDPAANLGIVKVDSDGAGYHILWGLTNEAVPTSELPAHFLSHCERIKATNGKDRVIMHCHATNLIALTYVLENDTAVFTRQLWEGSTECLVVFPDGVGILPWMVPGTDEIGQATAQEMQKHSLVLWPFHGVFGSGPTLDETFGLIDTAEKSAQVLVKVYSMGGMKQTISREELIALGKRFGVTPLASALAL", "length": 274, "reference_go_mf": ["GO:0016832", "GO:0042802", "GO:0008994"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_b81b8b4b1e5a8e8190bf"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_646_1p4r_assembly1", "enzyme_name": "phosphoribosylaminoimidazolecarboxamide formyltransferase", "ec": ["2.1.2.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P31939", "alignment_score": 1178.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [3, 592], "sequence": "MAPGQLALFSVSDKTGLVEFARNLTALGLNLVASGGTAKALRDAGLAVRDVSELTGFPEMLGGRVKTLHPAVHAGILARNIPEDNADMARLDFNLIRVVACNLYPFVKTVASPGVTVEEAVEQIDIGGVTLLRAAAKNHARVTVVCEPEDYVVVSTEMQSSESKDTSLETRRQLALKAFTHTAQYDEAISDYFRKQYSKGVSQMPLRYGMNPHQTPAQLYTLQPKLPITVLNGAPGFINLCDALNAWQLVKELKEALGIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLYKTLTPISAAYARARGADRMSSFGDFVALSDVCDVPTAKIISREVSDGIIAPGYEEEALTILSKKKNGNYCVLQMDQSYKPDENEVRTLFGLHLSQKRNNGVVDKSLFSNVVTKNKDLPESALRDLIVATIAVKYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAGDKANYWWLRHHPQVLSMKFKTGVKRAEISNAIDQYVTGTIGEDEDLIKWKALFEEVPELLTEAEKKEWVEKLTEVSISSDAFFPFRDNVDRAKRSGVAYIAAPSGSAADKVVIEACDELGIILAHTNLRLFHH", "length": 592, "reference_go_mf": ["GO:0045296", "GO:0003937", "GO:0004643", "GO:0042803"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_abc3fdb3eb18f826f80d"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P31939", "alignment_score": 1176.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [4, 592], "sequence": "MAPGQLALFSVSDKTGLVEFARNLTALGLNLVASGGTAKALRDAGLAVRDVSELTGFPEMLGGRVKTLHPAVHAGILARNIPEDNADMARLDFNLIRVVACNLYPFVKTVASPGVTVEEAVEQIDIGGVTLLRAAAKNHARVTVVCEPEDYVVVSTEMQSSESKDTSLETRRQLALKAFTHTAQYDEAISDYFRKQYSKGVSQMPLRYGMNPHQTPAQLYTLQPKLPITVLNGAPGFINLCDALNAWQLVKELKEALGIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLYKTLTPISAAYARARGADRMSSFGDFVALSDVCDVPTAKIISREVSDGIIAPGYEEEALTILSKKKNGNYCVLQMDQSYKPDENEVRTLFGLHLSQKRNNGVVDKSLFSNVVTKNKDLPESALRDLIVATIAVKYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAGDKANYWWLRHHPQVLSMKFKTGVKRAEISNAIDQYVTGTIGEDEDLIKWKALFEEVPELLTEAEKKEWVEKLTEVSISSDAFFPFRDNVDRAKRSGVAYIAAPSGSAADKVVIEACDELGIILAHTNLRLFHH", "length": 592, "reference_go_mf": ["GO:0045296", "GO:0003937", "GO:0004643", "GO:0042803"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_abc3fdb3eb18f826f80d"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_647_1kny_assembly1", "enzyme_name": "kanamycin nucleotidyltransferase", "ec": ["2.7.7.-"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P05057", "alignment_score": 503.0, "observed_coverage": 1.0, "aligned_identity": 0.9960474308300395, "canonical_span": [0, 253], "sequence": "MNGPIIMTREERMKIVHEIKERILDKYGDDVKAIGVYGSLGRQTDGPYSDIEMMCVMSTEEAEFSHEWTTGEWKVEVNFDSEEILLDYASQVESDWPLTHGQFFSILPIYDSGGYLEKVYQTAKSVEAQTFHDAICALIVEELFEYAGKWRNIRVQGPTTFLPSLTVQVAMAGAMLIGLHHRICYTTSASVLTEAVKQSDLPSGYDHLCQFVMSGQLSDSEKLLESLENFWNGIQEWTERHGYIVDVSKRIPF", "length": 253, "reference_go_mf": ["GO:0016779"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_a7c98e4cbf37efcccb91"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P05057", "alignment_score": 503.0, "observed_coverage": 1.0, "aligned_identity": 0.9960474308300395, "canonical_span": [0, 253], "sequence": "MNGPIIMTREERMKIVHEIKERILDKYGDDVKAIGVYGSLGRQTDGPYSDIEMMCVMSTEEAEFSHEWTTGEWKVEVNFDSEEILLDYASQVESDWPLTHGQFFSILPIYDSGGYLEKVYQTAKSVEAQTFHDAICALIVEELFEYAGKWRNIRVQGPTTFLPSLTVQVAMAGAMLIGLHHRICYTTSASVLTEAVKQSDLPSGYDHLCQFVMSGQLSDSEKLLESLENFWNGIQEWTERHGYIVDVSKRIPF", "length": 253, "reference_go_mf": ["GO:0016779"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_a7c98e4cbf37efcccb91"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_648_1snn_assembly1", "enzyme_name": "3,4-dihydroxy-2-butanone-4-phosphate synthase", "ec": ["4.1.99.12"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q60364", "alignment_score": 435.0, "observed_coverage": 1.0, "aligned_identity": 0.9954337899543378, "canonical_span": [1, 220], "sequence": "MNNVEKAIEALKKGEIILVYDSDEREGETDMVVASQFITPEHIRIMRKDAGGLICTALHPDICNKLGIPFMVDILEFASQKFKVLRELYPNDIPYDEKSSFSITINHRKTFTGITDNDRAFTIKKLAELVKEGRFNDFGKEFRSPGHVTLLRAAEGLVKNRQGHTEMTVALAELANLVPITTICEMMGDDGNAMSKNETKRYAEKHNLIYLSGEEIINYYLDKYLKD", "length": 227, "reference_go_mf": ["GO:0008686", "GO:0000287", "GO:0030145"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_6eb50160ff9b8b3681ff"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "Q60364", "alignment_score": 435.0, "observed_coverage": 1.0, "aligned_identity": 0.9954337899543378, "canonical_span": [2, 221], "sequence": "MNNVEKAIEALKKGEIILVYDSDEREGETDMVVASQFITPEHIRIMRKDAGGLICTALHPDICNKLGIPFMVDILEFASQKFKVLRELYPNDIPYDEKSSFSITINHRKTFTGITDNDRAFTIKKLAELVKEGRFNDFGKEFRSPGHVTLLRAAEGLVKNRQGHTEMTVALAELANLVPITTICEMMGDDGNAMSKNETKRYAEKHNLIYLSGEEIINYYLDKYLKD", "length": 227, "reference_go_mf": ["GO:0008686", "GO:0000287", "GO:0030145"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_6eb50160ff9b8b3681ff"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_64_1d6m_assembly1", "enzyme_name": "DNA topoisomerase (type III)", "ec": ["5.6.2.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P14294", "alignment_score": 1197.5, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 609], "sequence": "MRLFIAEKPSLARAIADVLPKPHRKGDGFIECGNGQVVTWCIGHLLEQAQPDAYDSRYARWNLADLPIVPEKWQLQPRPSVTKQLNVIKRFLHEASEIVHAGDPDREGQLLVDEVLDYLQLAPEKRQQVQRCLINDLNPQAVERAIDRLRSNSEFVPLCVSALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVKAHIVTPADERFTAIWQPSEACEPYQDEEGRLLHRPLAEHVVNRISGQPAIVTSYNDKRESESAPLPFSLSALQIEAAKRFGLSAQNVLDICQKLYETHKLITYPRSDCRYLPEEHFAGRHAVMNAISVHAPDLLPQPVVDPDIRNRCWDDKKVDAHHAIIPTARSSAINLTENEAKVYNLIARQYLMQFCPDAVFRKCVIELDIAKGKFVAKARFLAEAGWRTLLGSKERDEENDGTPLPVVAKGDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKILRATDGLGTEATRAGIIELLFKRGFLTKKGRYIHSTDAGKALFHSLPEMATRPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLYQLIDQAKRTPVRQFRGIVAPGSGGSADKKKAAPRKRSAKKSPPADEVGSGAIA", "length": 653, "reference_go_mf": ["GO:0003917", "GO:0000287", "GO:0098847"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_19cc6429ae37e1f03d1d"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_651_1ig8_assembly1", "enzyme_name": "hexokinase (type II)", "ec": ["2.7.1.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P04807", "alignment_score": 938.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [17, 486], "sequence": "MVHLGPKKPQARKGSMADVPKELMQQIENFEKIFTVPTETLQAVTKHFISELEKGLSKKGGNIPMIPGWVMDFPTGKESGDFLAIDLGGTNLRVVLVKLGGDRTFDTTQSKYRLPDAMRTTQNPDELWEFIADSLKAFIDEQFPQGISEPIPLGFTFSFPASQNKINEGILQRWTKGFDIPNIENHDVVPMLQKQITKRNIPIEVVALINDTTGTLVASYYTDPETKMGVIFGTGVNGAYYDVCSDIEKLQGKLSDDIPPSAPMAINCEYGSFDNEHVVLPRTKYDITIDEESPRPGQQTFEKMSSGYYLGEILRLALMDMYKQGFIFKNQDLSKFDKPFVMDTSYPARIEEDPFENLEDTDDLFQNEFGINTTVQERKLIRRLSELIGARAARLSVCGIAAICQKRGYKTGHIAADGSVYNRYPGFKEKAANALKDIYGWTQTSLDDYPIKIVPAEDGSGAGAAVIAALAQKRIAEGKSVGIIGA", "length": 486, "reference_go_mf": ["GO:0005524", "GO:0005536", "GO:0008865", "GO:0004340", "GO:0004396", "GO:0019158"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_5583212b1e90650354e5"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_652_1nvm_assembly1", "enzyme_name": "4-hydroxy-2-oxovalerate aldolase", "ec": ["4.1.3.39"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P51016", "alignment_score": 680.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 341], "sequence": "MTFNPSKKLYISDVTLRDGSHAIRHQYTLDDVRAIARALDKAKVDSIEVAHGDGLQGSSFNYGFGRHTDLEYIEAVAGEISHAQIATLLLPGIGSVHDLKNAYQAGARVVRVATHCTEADVSKQHIEYARNLGMDTVGFLMMSHMIPAEKLAEQGKLMESYGATCIYMADSGGAMSMNDIRDRMRAFKAVLKPETQVGMHAHHNLSLGVANSIVAVEEGCDRVDASLAGMGAGAGNAPLEVFIAVAERLGWNHGTDLYTLMDAADDIVRPLQDRPVRVDRETLGLGYAGVYSSFLRHAEIAAAKYNLKTLDILVELGHRRMVGGQEDMIVDVALDLLAAHKENRA", "length": 345, "reference_go_mf": ["GO:0003852", "GO:0008701", "GO:0030145"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_02fa0f095508b63687a6"}, "alternative_alignments": [{"accession": "Q52060", "alignment_score": 9.0, "observed_coverage": 0.01764705882352941, "aligned_identity": 0.8333333333333334, "canonical_span": [13, 19], "length": 312, "reference_go_mf": ["GO:0008774", "GO:0051287", "GO:0050661"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_653_1kzh_assembly1", "enzyme_name": "diphosphate---fructose-6-phosphate 1-phosphotransferase", "ec": ["2.7.1.90"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P70826", "alignment_score": 1100.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [3, 553], "sequence": "MNTSLFKQERQKYIPKLPNILKKDFNNISLVYGENTEAIQDRQALKEFFKNTYGLPIISFTEGESSLSFSKALNIGIILSGGPAPGGHNVISGVFDAIKKFNPNSKLFGFKGGPLGLLENDKIELTESLINSYRNTGGFDIVSSGRTKIETEEHYNKALFVAKENNLNAIIIIGGDDSNTNAAILAEYFKKNGENIQVIGVPKTIDADLRNDHIEISFGFDSATKIYSELIGNLCRDAMSTKKYWHFVKLMGRSASHVALECALKTHPNICIVSEEVLAKKKTLSEIIDEMVSVILKRSLNGDNFGVVIVPEGLIEFIPEVKSLMLELCDIFDKNEGEFKGLNIEKMKEIFVAKLSDYMKGVYLSLPLFIQFELIKSILERDPHGNFNVSRVPTEKLFIEMIQSRLNDMKKRGEYKGSFTPVDHFFGYEGRSAFPSNFDSDYCYSLGYNAVVLILNGLTGYMSCIKNLNLKPTDWIAGGVPLTMLMNMEERYGEKKPVIKKALVDLEGRPFKEFVKNRDKWALNNLYLYPGPVQYFGSSEIVDEITETLKLELLK", "length": 555, "reference_go_mf": ["GO:0003872", "GO:0005524", "GO:0047334"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_c00a5b060cbec248e5c2"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_655_1p7m_assembly1", "enzyme_name": "DNA-3-methyladenine glycosylase I", "ec": ["3.2.2.20"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P05100", "alignment_score": 365.0, "observed_coverage": 1.0, "aligned_identity": 0.983957219251337, "canonical_span": [0, 187], "sequence": "MERCGWVSQDPLYIAYHDNEWGVPETDSKKLFEMICLEGQQAGLSWITVLKKRENYRACFHQFDPVKVAAMQEEDVERLVQDAGIIRHRGKIQAIIGNARAYLQMEQNGEPFVDFVWSFVNHQPQVTQATTLSEIPTSTSASDALSKALKKRGFKFVGTTICYSFMQACGLVNDHVVGCCCYPGNKP", "length": 187, "reference_go_mf": ["GO:0008725"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_c5bb3d2d9ad461c0e3de"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_656_1kaz_assembly1", "enzyme_name": "adenosinetriphosphatase", "ec": ["3.6.1.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P19120", "alignment_score": 753.0, "observed_coverage": 1.0, "aligned_identity": 0.9973544973544973, "canonical_span": [3, 381], "sequence": "MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSSMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELEKVCNPIITKLYQSAGGMPGGMPGGMPGGFPGGGAPPSGGASSGPTIEEVD", "length": 650, "reference_go_mf": ["GO:0005524", "GO:0016887", "GO:0031072", "GO:0044183", "GO:0030674"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_a35455d49883d3a03f3a"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_657_1hr6_assembly1", "enzyme_name": "mitochondrial processing peptidase", "ec": ["3.4.24.64"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P10507", "alignment_score": 872.0, "observed_coverage": 1.0, "aligned_identity": 0.9954441913439636, "canonical_span": [23, 462], "sequence": "MFSRTASKFRNTRRLLSTISSQIPGTRTSKLPNGLTIATEYIPNTSSATVGIFVDAGSRAENVKNNGTAHFLEHLAFKGTQNRSQQGIELEIENIGSHLNAYTSRENTVYYAKSLQEDIPKAVDILSDILTKSVLDNSAIERERDVIIRESEEVDKMYDEVVFDHLHEITYKDQPLGRTILGPIKNIKSITRTDLKDYITKNYKGDRMVLAGAGAVDHEKLVQYAQKYFGHVPKSESPVPLGSPRGPLPVFCRGERFIKENTLPTTHIAIALEGVSWSAPDYFVALATQAIVGNWDRAIGTGTNSPSPLAVAASQNGSLANSYMSFSTSYADSGLWGMYIVTDSNEHNVQLIVNEILKEWKRIKSGKISDAEVNRAKAQLKAALLLSLDGSTAIVEDIGRQVVTTGKRLSPEEVFEQVDKITKDDIIMWANYRLQNKPVSMVALGNTSTVPNVSYIEEKLNQ", "length": 462, "reference_go_mf": ["GO:0046872", "GO:0004222", "GO:0009003"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_317f8e9ad44bf2059d9b"}, "alternative_alignments": [{"accession": "P11914", "alignment_score": 20.0, "observed_coverage": 0.07061503416856492, "aligned_identity": 0.5483870967741935, "canonical_span": [365, 396], "length": 482, "reference_go_mf": ["GO:0061133", "GO:0046872", "GO:0004222"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_658_1fhl_assembly1", "enzyme_name": "arabinogalactan endo-1,4-beta-galactosidase", "ec": ["3.2.1.89"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P48842", "alignment_score": 668.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [16, 350], "sequence": "MFASLLLAALPLLTHAALTYRGADISSLLLLEDEGYSYKNLNGQTQALETILADAGINSIRQRVWVNPSDGSYDLDYNLELAKRVKAAGMSLYLDLHLSDTWADPSDQTTPSGWSTTDLGTLKWQLYNYTLEVCNTFAENDIDIEIISIGNEIRAGLLWPLGETSSYSNIGALLHSGAWGVKDSNLATTPKIMIHLDDGWSWDQQNYFYETVLATGELLSTDFDYFGVSYYPFYSASATLASLKTSLANLQSTYDKPVVVVETNWPVSCPNPAYAFPSDLSSIPFSVAGQQEFLEKLAAVVEATTDGLGVYYWEPAWIGNAGLGSSCADNLMVDYTTDEVYESIETLGEL", "length": 350, "reference_go_mf": ["GO:0031218", "GO:0015926"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_7e5a248b4b5ff319345e"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_65_1gim_assembly1", "enzyme_name": "adenylosuccinate synthase", "ec": ["6.3.4.4"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0A7D4", "alignment_score": 862.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 432], "sequence": "MGNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKEMKELEDRGIPVRERLLLSEACPLILDYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKETFAEKLKEVMEYHNFQLVNYYKAEAVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVATGSGLGPRYVDYVLGILKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDTVAVRRAVQLNSLSGFCLTKLDVLDGLKEVKLCVAYRMPDGREVTTTPLAADDWKGVEPIYETMPGWSESTFGVKDRSGLPQAALNYIKRIEELTGVPIDIISTGPDRTETMILRDPFDA", "length": 432, "reference_go_mf": ["GO:0004019", "GO:0005525", "GO:0097216", "GO:0000287"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_6b30d8caf49e7b7f867d"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_660_1do6_assembly1", "enzyme_name": "superoxide reductase", "ec": ["1.15.1.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P82385", "alignment_score": 248.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 124], "sequence": "MISETIRSGDWKGEKHVPVIEYEREGELVKVKVQVGKEIPHPNTTEHHIRYIELYFLPEGENFVYQVGRVEFTAHGESVNGPNTSDVYTEPIAYFVLKTKKKGKLYALSYCNIHGLWENEVTLE", "length": 124, "reference_go_mf": ["GO:0005506", "GO:0050605"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_f36e2e7a59f3d5a36e69"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_663_1rk2_assembly1", "enzyme_name": "ribokinase", "ec": ["2.7.1.15"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0A9J6", "alignment_score": 610.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [3, 308], "sequence": "MQNAGSLVVLGSINADHILNLQSFPTPGETVTGNHYQVAFGGKGANQAVAAGRSGANIAFIACTGDDSIGESVRQQLATDNIDITPVSVIKGESTGVALIFVNGEGENVIGIHAGANAALSPALVEAQRERIANASALLMQLESPLESVMAAAKIAHQNKTIVALNPAPARELPDELLALVDIITPNETEAEKLTGIRVENDEDAAKAAQVLHEKGIRTVLITLGSRGVWASVNGEGQRVPGFRVQAVDTIAAGDTFNGALITALLEEKPLPEAIRFAHAAAAIAVTRKGAQPSVPWREEIDAFLDRQR", "length": 309, "reference_go_mf": ["GO:0005524", "GO:0046872", "GO:0042803", "GO:0004747"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_74c212c724facecfe3c8"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_665_1ez1_assembly1", "enzyme_name": "Formate-dependent phosphoribosylglycinamide formyltransferase", "ec": ["2.1.2.-"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P33221", "alignment_score": 771.5, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 392], "sequence": "MTLLGTALRPAATRVMLLGSGELGKEVAIECQRLGVEVIAVDRYADAPAMHVAHRSHVINMLDGDALRRVVELEKPHYIVPEIEAIATDMLIQLEEEGLNVVPCARATKLTMNREGIRRLAAEELQLPTSTYRFADSESLFREAVADIGYPCIVKPVMSSSGKGQTFIRSAEQLAQAWKYAQQGGRAGAGRVIVEGVVKFDFEITLLTVSAVDGVHFCAPVGHRQEDGDYRESWQPQQMSPLALERAQEIARKVVLALGGYGLFGVELFVCGDEVIFSEVSPRPHDTGMVTLISQDLSEFALHVRAFLGLPVGGIRQYGPAASAVILPQLTSQNVTFDNVQNAVGADLQIRLFGKPEIDGSRRLGVALATAESVVDAIERAKHAAGQVKVQG", "length": 392, "reference_go_mf": ["GO:0008776", "GO:0005524", "GO:0000287", "GO:0043815", "GO:0004644"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_2925763e116557ae8a1c"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_666_1mpx_assembly1", "enzyme_name": "alpha-amino-acid esterase", "ec": ["3.1.1.43"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q6YBS3", "alignment_score": 1084.0, "observed_coverage": 0.9949664429530202, "aligned_identity": 1.0, "canonical_span": [27, 637], "sequence": "MRRLATCLLATAIAAASGSAWAQTSPMTPDITGKPFVAADASNDYIKREVMIPMRDGVKLHTVIVLPKGAKNAPIVLTRTPYDASGRTERLASPHMKDLLSAGDDVFVEGGYIRVFQDVRGKYGSEGDYVMTRPLRGPLNPSEVDHATDAWDTIDWLVKNVSESNGKVGMIGSSYEGFTVVMALTNPHPALKVAVPESPMIDGWMGDDWFNYGAFRQVNFDYFTGQLSKRGKGAGIARQGHDDYSNFLQAGSAGDFAKAAGLEQLPWWHKLTEHAAYDAFWQEQALDKVMARTPLKVPTMWLQGLWDQEDMWGAIHSYAAMEPRDKRNTLNYLVMGPWRHSQVNYDGSALGALNFEGDTARQFRHDVLRPFFDQYLVDGAPKADTPPVFIYNTGENHWDRLKAWPRSCDKGCAATSKPLYLQAGGKLSFQPPVAGQAGFEEYVSDPAKPVPFVPRPVDFADRAMWTTWLVHDQRFVDGRPDVLTFVTEPLTEPLQIAGAPDVHLQASTSGSDSDWVVKLIDVYPEEMASNPKMGGYELPVSLAIFRGRYRESFSTPKPLTSNQPLAFQFGLPTANHTFQPGHRVMVQVQSSLFPLYDRNPQTYVPNIFFAKPGDYQKATQRVYVSPEQPSYISLPVR", "length": 637, "reference_go_mf": ["GO:0047658", "GO:0008239"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_fb3bc68245c997e7810f"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_668_1lml_assembly1", "enzyme_name": "leishmanolysin", "ec": ["3.4.24.36"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P08148", "alignment_score": 914.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [99, 574], "sequence": "MSVDSSSTHRRRCVAARLVRLAAAGAAVTVAVGTAAAWAHAGALQHRCVHDAMQARVRQSVADHHKAPGAVSAVGLPYVTLDAAHTAAAADPRPGSARSVVRDVNWGALRIAVSTEDLTDPAYHCARVGQHVKDHAGAIVTCTAEDILTNEKRDILVKHLIPQAVQLHTERLKVQQVQGKWKVTDMVGDICGDFKVPQAHITEGFSNTDFVMYVASVPSEEGVLAWATTCQTFSDGHPAVGVINIPAANIASRYDQLVTRVVTHEMAHALGFSGPFFEDARIVANVPNVRGKNFDVPVINSSTAVAKAREQYGCDTLEYLEVEDQGGAGSAGSHIKMRNAQDELMAPAAAAGYYTALTMAIFQDLGFYQADFSKAEVMPWGQNAGCAFLTNKCMEQSVTQWPAMFCNESEDAIRCPTSRLSLGACGVTRHPGLPPYWQYFTDPSLAGVSAFMDYCPVVVPYSDGSCTQRASEAHASLLPFNVFSDAARCIDGAFRPKATDGIVKSYAGLCANVQCDTATRTYSVQVHGSNDYTNCTPGLRVELSTVSNAFEGGGYITCPPYVEVCQGNVQAAKDGGNTAAGRRGPRAAATALLVAALLAVAL", "length": 602, "reference_go_mf": ["GO:0004222", "GO:0008237"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_1ad3f0b981d51120e8d1"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_669_1b7b_assembly1", "enzyme_name": "carbamate kinase", "ec": ["2.7.2.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0A2X8", "alignment_score": 614.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 308], "sequence": "MGKKMVVALGGNAILSNDASAHAQQQALVQTSAYLVHLIKQGHRLIVSHGNGPQVGNLLLQQQAADSEKNPAMPLDTCVAMTQGSIGYWLSNALNQELNKAGIKKQVATVLTQVVVDPADEAFKNPTKPIGPFLTEAEAKEAMQAGAIFKEDAGRGWRKVVPSPKPIDIHEAETINTLIKNDIITISCGGGGIPVVGQELKGVEAVIDKDFASEKLAELVDADALVILTGVDYVCINYGKPDEKQLTNVTVAELEEYKQAGHFAPGSMLPKIEAAIQFVESQPNKQAIITSLENLGSMSGDEIVGTVVTK", "length": 310, "reference_go_mf": ["GO:0008804"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_84422b26979ea102304b"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_66_1daa_assembly1", "enzyme_name": "D-alanine transaminase", "ec": ["2.6.1.21"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P19938", "alignment_score": 554.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 278], "sequence": "MGYTLWNDQIVKDEEVKIDKEDRGYQFGDGVYEVVKVYNGEMFTVNEHIDRLYASAEKIRITIPYTKDKFHQLLHELVEKNELNTGHIYFQVTRGTSPRAHQFPENTVKPVIIGYTKENPRPLENLEKGVKATFVEDIRWLRCDIKSLNLLGAVLAKQEAHEKGCYEAILHRNNTVTEGSSSNVFGIKDGILYTHPANNMILKGITRDVVIACANEINMPVKEIPFTTHEALKMDELFVTSTTSEITPVIEIDGKLIRDGKVGEWTRKLQKQFETKIPKPLHI", "length": 283, "reference_go_mf": ["GO:0047810", "GO:0030170"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_c134e56735adf8e75aa5"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_670_1jxh_assembly1", "enzyme_name": "hydroxymethylpyrimidine kinase", "ec": ["2.7.1.49"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P55882", "alignment_score": 467.5, "observed_coverage": 1.0, "aligned_identity": 0.9959677419354839, "canonical_span": [0, 266], "sequence": "MQRINALTIAGTDPSGGAGIQADLKTFSALGAYGCSVITALVAQNTCGVQSVYRIEPDFVAAQLDSVFSDVRIDTTKIGMLAETDIVEAVAERLQRHHVRNVVLDTVMLAKSGDPLLSPSAIETLRVRLLPQVSLITPNLPEAAALLDAPHARTEQEMLAQGRALLAMGCEAVLMKGGHLEDAQSPDWLFTREGEQRFSAPRVNTKNTHGTGCTLSAALAALRPRHRSWGETVNEAKAWLSAALAQADTLEVGKGIGPVHHFHAWW", "length": 266, "reference_go_mf": ["GO:0008902", "GO:0008972"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_5acbdf8fb814f6dabf1f"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_671_1fo6_assembly1", "enzyme_name": "N-carbamoyl-D-amino-acid hydrolase", "ec": ["3.5.1.77"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q44185", "alignment_score": 601.0, "observed_coverage": 1.0, "aligned_identity": 0.9966887417218543, "canonical_span": [2, 304], "sequence": "MTRQMILAVGQQGPIARAETREQVVGRLLDMLTNAASRGVNFIVFPELALTTFFPRWHFTDEAELDSFYETEMPGPVVRPLFETAAELGIGFNLGYAELVVEGGVKRRFNTSILVDKSGKIVGKYRKIHLPGHKEYEAYRPFQHLEKRYFEPGDLGFPVYDVDAAKMGMFICNDRRWPETWRVMGLKGAEIICGGYNTPTHNPPVPQHDHLTSFHHLLSMQAGSYQNGAWSAAAGKVGMEEGCMLLGHSCIVAPTGEIVALTTTLEDEVITAAVDLDRCRELREHIFNFKAHRQPQHYGLIAEF", "length": 304, "reference_go_mf": ["GO:0047417"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_cdb91dbd6e99211720b7"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_672_1bou_assembly1", "enzyme_name": "protocatechuate 4,5-dioxygenase", "ec": ["1.13.11.8"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P22636", "alignment_score": 596.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 299], "sequence": "MARVTTGITSSHIPALGAAIQTGTSDNDYWGPVFKGYQPIRDWIKQPGNMPDVVILVYNDHASAFDMNIIPTFAIGCAETFKPADEGWGPRPVPDVKGHPDLAWHIAQSLILDEFDMTIMNQMDVDHGCTVPLSMIFGEPEEWPCKVIPFPVNVVTYPPPSGKRCFALGDSIRAAVESFPEDLNVHVWGTGGMSHQLQGPRAGLINKEFDLNFIDKLISDPEELSKMPHIQYLRESGSEGVELVMWLIMRGALPEKVRDLYTFYHIPASNTALGAMILQPEETAGTPLEPRKVMSGHSLAQA", "length": 302, "reference_go_mf": ["GO:0008198", "GO:0018579"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_ac13b74d9967028edc0a"}, "alternative_alignments": [{"accession": "P22635", "alignment_score": 7.0, "observed_coverage": 0.016778523489932886, "aligned_identity": 0.8, "canonical_span": [13, 18], "length": 139, "reference_go_mf": ["GO:0018579"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_673_1kdg_assembly1", "enzyme_name": "cellobiose dehydrogenase (acceptor)", "ec": ["1.1.99.18"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q01738", "alignment_score": 1082.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [232, 773], "sequence": "MLGRSLLALLPFVGLAFSQSASQFTDPTTGFQFTGITDPVHDVTYGFVFPPLATSGAQSTEFIGEVVAPIASKWIGIALGGAMNNDLLLVAWANGNQIVSSTRWATGYVQPTAYTGTATLTTLPETTINSTHWKWVFRCQGCTEWNNGGGIDVTSQGVLAWAFSNVAVDDPSDPQSTFSEHTDFGFFGIDYSTAHSANYQNYLNGDSGNPTTTSTKPTSTSSSVTTGPTVSATPYDYIIVGAGPGGIIAADRLSEAGKKVLLLERGGPSTKQTGGTYVAPWATSSGLTKFDIPGLFESLFTDSNPFWWCKDITVFAGCLVGGGTSVNGALYWYPNDGDFSSSVGWPSSWTNHAPYTSKLSSRLPSTDHPSTDGQRYLEQSFNVVSQLLKGQGYNQATINDNPNYKDHVFGYSAFDFLNGKRAGPVATYLQTALARPNFTFKTNVMVSNVVRNGSQILGVQTNDPTLGPNGFIPVTPKGRVILSAGAFGTSRILFQSGIGPTDMIQTVQSNPTAAAALPPQNQWINLPVGMNAQDNPSINLVFTHPSIDAYENWADVWSNPRPADAAQYLANQSGVFAGASPKLNFWRAYSGSDGFTRYAQGTVRPGAASVNSSLPYNASQIFTITVYLSTGIQSRGRIGIDAALRGTVLTPPWLVNPVDKTVLLQALHDVVSNIGSIPGLTMITPDVTQTLEEYVDAYDPATMNSNHWVSSTTIGSSPQSAVVDSNVKVFGTNNLFIVDAGIIPHLPTGNPQGTLMSAAEQAAAKILALAGGP", "length": 773, "reference_go_mf": ["GO:0047735", "GO:0050660"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_9874ed1aa33d9d503228"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_674_1uf7_assembly1", "enzyme_name": "N-carbamoyl-D-amino-acid hydrolase", "ec": ["3.5.1.77"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P60327", "alignment_score": 600.0, "observed_coverage": 1.0, "aligned_identity": 0.9933993399339934, "canonical_span": [1, 304], "sequence": "MTRQMILAVGQQGPIARAETREQVVVRLLDMLTKAASRGANFIVFPELALTTFFPRWHFTDEAELDSFYETEMPGPVVRPLFEKAAELGIGFNLGYAELVVEGGVKRRFNTSILVDKSGKIVGKYRKIHLPGHKEYEAYRPFQHLEKRYFEPGDLGFPVYDVDAAKMGMFICNDRRWPEAWRVMGLRGAEIICGGYNTPTHNPPVPQHDHLTSFHHLLSMQAGSYQNGAWSAAAGKVGMEENCMLLGHSCIVAPTGEIVALTTTLEDEVITAAVDLDRCRELREHIFNFKQHRQPQHYGLIAEL", "length": 304, "reference_go_mf": ["GO:0047417"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_6ddaaee04828ae345005"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_675_1pix_assembly1", "enzyme_name": "glutaconyl-CoA decarboxylase", "ec": ["7.2.4.5"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q06700", "alignment_score": 1172.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 587], "sequence": "MGFYSMPRYFQNMPQVGKPLKKADAANEEQLKKIEEEIHQLIKEAQEAGKADADVNKRGELTALQRIEKLVEPGSWRPLNTLFNPQGNKNGSVAIVKGLGRVNGKWCVVVASDNKKLAGAWVPGQAECLLRASDTAKTLHVPLVYVLNCSGVKFDEQEKVYPNRRGGGTPFFRNAELNQLGIPVIVGIYGTNPAGGGYHSISPTVIIAHEKANMAVGGAGIMGGMNPKGHVDLEYANEIADMVDRTGKTEPPGAVDIHYTETGFMREVYASEEGVLEGIKKYVGMLPKYDPEFFRVDDPKAPAFPADDLYSMVPLNDKRAYDIYNVIARLFDNSELHEYKKGYGPEMVTGLAKVNGLLVGVVANVQGLLMNYPEYKAAGSVGIGGKLYRQGLVKMNEFVTLCARDRLPIVWIQDTTGIDVGNDAEKAELLGLGQSLIYSIQTSHIPQFEITLRKGTAAAHYVLGGPQGNDTNAFSIGTAATEIAVMNGETAATAMYSRRLAKDRKAGKDLQPTIDKMNNLIQAFYTKSRPKVCAELGLVDEIVDMNKIRGYVEAFTEAAYQNPESICPFHQMILPRAIREFETFVKK", "length": 587, "reference_go_mf": ["GO:0018801", "GO:0004485"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_2994c72d4533191c01b3"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "Q06700", "alignment_score": 1172.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 587], "sequence": "MGFYSMPRYFQNMPQVGKPLKKADAANEEQLKKIEEEIHQLIKEAQEAGKADADVNKRGELTALQRIEKLVEPGSWRPLNTLFNPQGNKNGSVAIVKGLGRVNGKWCVVVASDNKKLAGAWVPGQAECLLRASDTAKTLHVPLVYVLNCSGVKFDEQEKVYPNRRGGGTPFFRNAELNQLGIPVIVGIYGTNPAGGGYHSISPTVIIAHEKANMAVGGAGIMGGMNPKGHVDLEYANEIADMVDRTGKTEPPGAVDIHYTETGFMREVYASEEGVLEGIKKYVGMLPKYDPEFFRVDDPKAPAFPADDLYSMVPLNDKRAYDIYNVIARLFDNSELHEYKKGYGPEMVTGLAKVNGLLVGVVANVQGLLMNYPEYKAAGSVGIGGKLYRQGLVKMNEFVTLCARDRLPIVWIQDTTGIDVGNDAEKAELLGLGQSLIYSIQTSHIPQFEITLRKGTAAAHYVLGGPQGNDTNAFSIGTAATEIAVMNGETAATAMYSRRLAKDRKAGKDLQPTIDKMNNLIQAFYTKSRPKVCAELGLVDEIVDMNKIRGYVEAFTEAAYQNPESICPFHQMILPRAIREFETFVKK", "length": 587, "reference_go_mf": ["GO:0018801", "GO:0004485"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_2994c72d4533191c01b3"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_676_1b65_assembly1", "enzyme_name": "D-stereospecific aminopeptidase (peptidase S58 family)", "ec": ["3.4.11.19"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q59632", "alignment_score": 718.5, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [8, 375], "sequence": "MTSQTPTRKPRARDLGLPFTGVTGPYNAITDVDGVGVGFQTIIENEPRPGRKRPARSGVTAILPHMQSETPVPVYAGVHRFNGNGEMTGTHWIEDGGYFLGPVVITNTHGIGMAHHATVRWMVDRYASTYQTDDFLWIMPVVAETYDGALNDINGFPVTEADVRKALDNVASGPVQEGNCGGGTGMITYGFKGGTGTASRVVEFGGRSFTIGALVQANHGQRDWLTIAGVPVGQHMRDGTPQSQLQERGSIIVVLATDLPLMPHQLKRLARRASIGIGRNGTPGGNNSGDIFIAFSTANQRPMQHRSAPFLDVEMVNDEPLDTVYLAAVDSVEEAVVNAMIAAEDMGGTPFDRLLVQAIDHERLRAVLRQYGRLA", "length": 375, "reference_go_mf": ["GO:0004177"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_0c3e58e911f51068e889"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_678_1ht1_assembly1", "enzyme_name": "HslU---HslV peptidase", "ec": ["3.4.25.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0A7B8", "alignment_score": 348.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 175], "sequence": "MTTIVSVRRNGHVVIAGDGQATLGNTVMKGNVKKVRRLYNDKVIAGFAGGTADAFTLFELFERKLEMHQGHLVKAAVELAKDWRTDRMLRKLEALLAVADETASLIITGNGDVVQPENDLIAIGSGGPYAQAAARALLENTELSAREIAEKALDIAGDICIYTNHFHTIEELSYKA", "length": 176, "reference_go_mf": ["GO:0005524", "GO:0042802", "GO:0000287", "GO:0019904", "GO:0004298"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_31549ad1aebe14a58456"}, "alternative_alignments": [{"accession": "P0A6H5", "alignment_score": 8.0, "observed_coverage": 0.022988505747126436, "aligned_identity": 1.0, "canonical_span": [432, 436], "length": 443, "reference_go_mf": ["GO:0005524", "GO:0016887", "GO:0042802", "GO:0000287", "GO:0008233", "GO:0036402", "GO:0019904"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_679_1nln_assembly1", "enzyme_name": "adenain", "ec": ["3.4.22.39"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P03252", "alignment_score": 406.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 204], "sequence": "MGSSEQELKAIVKDLGCGPYFLGTYDKRFPGFVSPHKLACAIVNTAGRETGGVHWMAFAWNPRSKTCYLFEPFGFSDQRLKQVYQFEYESLLRRSAIASSPDRCITLEKSTQSVQGPNSAACGLFCCMFLHAFANWPQTPMDHNPTMNLITGVPNSMLNSPQVQPTLRRNQEQLYSFLERHSPYFRSHSAQIRSATSFCHLKNM", "length": 204, "reference_go_mf": ["GO:0004197", "GO:0008234", "GO:0003677"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_0225e05635d224925cab"}, "alternative_alignments": [{"accession": "P03274", "alignment_score": 8.0, "observed_coverage": 0.034482758620689655, "aligned_identity": 0.7142857142857143, "canonical_span": [134, 141], "length": 250, "reference_go_mf": [], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_67_1pjb_assembly1", "enzyme_name": "alanine dehydrogenase", "ec": ["1.4.1.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "O52942", "alignment_score": 722.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 361], "sequence": "MEIGVPKEIKNQEFRVGLSPSSVRTLVEAGHTVFIETQAGIGAGFADQDYVQAGAQVVPSAKDAWSREMVVKVKEPLPAEYDLMQKDQLLFTYLHLAAARELTEQLMRVGLTAIAYETVELPNRSLPLLTPMSIIAGRLSVQFGARFLERQQGGRGVLLGGVPGVKPGKVVILGGGVVGTEAAKMAVGLGAQVQIFDINVERLSYLETLFGSRVELLYSNSAEIETAVAEADLLIGAVLVPGRRAPILVPASLVEQMRTGSVIVDVAVDQGGCVETLHPTSHTQPTYEVFGVVHYGVPNMPGAVPWTATQALNNSTLPYVVKLANQGLKALETDDALAKGLNVQAHRLVHPAVQQVFPDLA", "length": 361, "reference_go_mf": ["GO:0000286"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_4f74904ccec4bcfe0e13"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_680_1nn4_assembly1", "enzyme_name": "ribose-5-phosphate isomerase", "ec": ["5.3.1.6"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P37351", "alignment_score": 292.0, "observed_coverage": 0.9182389937106918, "aligned_identity": 1.0, "canonical_span": [0, 146], "sequence": "MKKIAFGCDHVGFILKHEIVAHLVERGVEVIDKGTWSSERTDYPHYASQVALAVAGGEVDGGILICGTGVGISIAANKFAGIRAVVCSEPYSAQLSRQHNDTNVLAFGSRVVGLELAKMIVDAWLGAQYEGGRHQQRVEAITAIEQRRN", "length": 149, "reference_go_mf": ["GO:0008786", "GO:0004751"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_26d0a001418975882f26"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P37351", "alignment_score": 294.0, "observed_coverage": 0.9245283018867925, "aligned_identity": 1.0, "canonical_span": [0, 147], "sequence": "MKKIAFGCDHVGFILKHEIVAHLVERGVEVIDKGTWSSERTDYPHYASQVALAVAGGEVDGGILICGTGVGISIAANKFAGIRAVVCSEPYSAQLSRQHNDTNVLAFGSRVVGLELAKMIVDAWLGAQYEGGRHQQRVEAITAIEQRRN", "length": 149, "reference_go_mf": ["GO:0008786", "GO:0004751"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_26d0a001418975882f26"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_681_1gq8_assembly1", "enzyme_name": "pectinesterase", "ec": ["3.1.1.11"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P83218", "alignment_score": 633.0, "observed_coverage": 1.0, "aligned_identity": 0.9968553459119497, "canonical_span": [1, 319], "sequence": "QSSTVTPNVVVAADGSGDYKTVSEAVAAAPEDSKTRYVIRIKAGVYRENVDVPKKKKNIMFLGDGRTSTIITASKNVQDGSTTFNSATVAAVGAGFLARDITFQNTAGAAKHQAVALRVGSDLSAFYRCDILAYQDSLYVHSNRQFFINCFIAGTVDFIFGNAAVVLQDCDIHARRPGSGQKNMVTAQGRTDPNQNTGIVIQKSRIGATSDLQPVQSSFPTYLGRPWKEYSRTVVMQSSITNVINPAGWFPWDGNFALDTLYYGEYQNTGAGAATSGRVTWKGFKVITSSTEAQGFTPGSFIAGGSWLKATTFPFSLGL", "length": 319, "reference_go_mf": ["GO:0030599"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_afef0aaea37304c4d30d"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_682_8pch_assembly1", "enzyme_name": "cathepsin H", "ec": ["3.4.22.16"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "O46427", "alignment_score": 440.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [115, 335], "sequence": "MWAVLSLLCAGAWLLGPPACGASNLAVSSFEKLHFKSWMVQHQKKYSLEEYHHRLQVFVSNWRKINAHNAGNHTFKLGLNQFSDMSFDEIRHKYLWSEPQNCSATKGNYLRGTGPYPPSMDWRKKGNFVSPVKNQGSCGSCWTFSTTGALESAVAIATGKMLSLAEQQLVDCAQNFNNHGCQGGLPSQAFEYIRYNKGIMGEDTYPYKGQDDHCKFQPDKAIAFVKDVANITMNDEEAMVEAVALYNPVSFAFEVTNDFLMYRKGIYSSTSCHKTPDKVNHAVLAVGYGEENGIPYWIVKNSWGPQWGMNGYFLIERGKNMCGLAACASYPIPLV", "length": 335, "reference_go_mf": ["GO:0004177", "GO:0008656", "GO:0004197", "GO:0008234", "GO:0004175", "GO:0030108", "GO:0004252", "GO:0070324"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_8e9886c2fd17b42539f3"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_683_1k4l_assembly1", "enzyme_name": "3,4-dihydroxy-2-butanone-4-phosphate synthase", "ec": ["4.1.99.12"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q8TG90", "alignment_score": 432.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [11, 227], "sequence": "MPSTDSIPKSNFDAIPDVIQAFKNGEFVVVLDDPSRENEADLIIAAESVTTEQMAFMVRHSSGLICAPLTPERTTALDLPQMVTHNADPRGTAYTVSVDAEHPSTTTGISAHDRALACRMLAAPDAQPSHFRRPGHVFPLRAVAGGVRARRGHTEAGVELCRLAGKRPVAVISEIVDDGQEVEGRAVRAAPGMLRGDECVAFARRWGLKVCTIEDMIAHVEKTEGKLETNGSG", "length": 233, "reference_go_mf": ["GO:0008686"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_71aa550edf15f78e2a72"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "Q8TG90", "alignment_score": 432.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [11, 227], "sequence": "MPSTDSIPKSNFDAIPDVIQAFKNGEFVVVLDDPSRENEADLIIAAESVTTEQMAFMVRHSSGLICAPLTPERTTALDLPQMVTHNADPRGTAYTVSVDAEHPSTTTGISAHDRALACRMLAAPDAQPSHFRRPGHVFPLRAVAGGVRARRGHTEAGVELCRLAGKRPVAVISEIVDDGQEVEGRAVRAAPGMLRGDECVAFARRWGLKVCTIEDMIAHVEKTEGKLETNGSG", "length": 233, "reference_go_mf": ["GO:0008686"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_71aa550edf15f78e2a72"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_684_1qaz_assembly1", "enzyme_name": "mannuronate-specific alginate lyase", "ec": ["4.2.2.3"], "controls": [{"chain": "A", "status": "missing_reference", "selected": null, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_685_1gp5_assembly1", "enzyme_name": "anthocyanidin synthase", "ec": ["1.14.20.4"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q96323", "alignment_score": 692.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 347], "sequence": "MVAVERVESLAKSGIISIPKEYIRPKEELESINDVFLEEKKEDGPQVPTIDLKNIESDDEKIRENCIEELKKASLDWGVMHLINHGIPADLMERVKKAGEEFFSLSVEEKEKYANDQATGKIQGYGSKLANNASGQLEWEDYFFHLAYPEEKRDLSIWPKTPSDYIEATSEYAKCLRLLATKVFKALSVGLGLEPDRLEKEVGGLEELLLQMKINYYPKCPQPELALGVEAHTDVSALTFILHNMVPGLQLFYEGKWVTAKCVPDSIVMHIGDTLEILSNGKYKSILHRGLVNKEKVRISWAVFCEPPKDKIVLKPLPEMVSVESPAKFPPRTFAQHIEHKLFGKEQEELVSEKND", "length": 356, "reference_go_mf": ["GO:0050589"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_02c4c7c538d10f543903"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_686_1e1a_assembly1", "enzyme_name": "diisopropyl-fluorophosphatase", "ec": ["3.1.8.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q7SIG4", "alignment_score": 624.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [2, 314], "sequence": "MEIPVIEPLFTKVTEDIPGAEGPVFDKNGDFYIVAPEVEVNGKPAGEILRIDLKTGKKTVICKPEVNGYGGIPAGCQCDRDANQLFVADMRLGLLVVQTDGTFEEIAKKDSEGRRMQGCNDCAFDYEGNLWITAPAGEVAPADYTRSMQEKFGSIYCFTTDGQMIQVDTAFQFPNGIAVRHMNDGRPYQLIVAETPTKKLWSYDIKGPAKIENKKVWGHIPGTHEGGADGMDFDEDNNLLVANWGSSHIEVFGPDGGQPKMRIRCPFEKPSNLHFKPQTKTIFVTEHENNAVWKFEWQRNGKKQYCETLKFGIF", "length": 314, "reference_go_mf": ["GO:0005509", "GO:0047862"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_71ec9b1cef7a859404ef"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_687_1roz_assembly1", "enzyme_name": "deoxyhypusine synthase", "ec": ["2.5.1.46"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P49366", "alignment_score": 672.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [27, 363], "sequence": "MEGSLEREAPAGALAAVLKHSSTLPPESTQVRGYDFNRGVNYRALLEAFGTTGFQATNFGRAVQQVNAMIEKKLEPLSQDEDQHADLTQSRRPLTSCTIFLGYTSNLISSGIRETIRYLVQHNMVDVLVTTAGGVEEDLIKCLAPTYLGEFSLRGKELRENGINRIGNLLVPNENYCKFEDWLMPILDQMVMEQNTEGVKWTPSKMIARLGKEINNPESVYYWAQKNHIPVFSPALTDGSLGDMIFFHSYKNPGLVLDIVEDLRLINTQAIFAKCTGMIILGGGVVKHHIANANLMRNGADYAVYINTAQEFDGSDSGARPDEAVSWGKIRVDAQPVKVYADASLVFPLLVAETFAQKMDAFMHEKNED", "length": 369, "reference_go_mf": ["GO:0034038", "GO:0042802"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_cd72f0041c68701d9e1d"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P49366", "alignment_score": 629.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [27, 363], "sequence": "MEGSLEREAPAGALAAVLKHSSTLPPESTQVRGYDFNRGVNYRALLEAFGTTGFQATNFGRAVQQVNAMIEKKLEPLSQDEDQHADLTQSRRPLTSCTIFLGYTSNLISSGIRETIRYLVQHNMVDVLVTTAGGVEEDLIKCLAPTYLGEFSLRGKELRENGINRIGNLLVPNENYCKFEDWLMPILDQMVMEQNTEGVKWTPSKMIARLGKEINNPESVYYWAQKNHIPVFSPALTDGSLGDMIFFHSYKNPGLVLDIVEDLRLINTQAIFAKCTGMIILGGGVVKHHIANANLMRNGADYAVYINTAQEFDGSDSGARPDEAVSWGKIRVDAQPVKVYADASLVFPLLVAETFAQKMDAFMHEKNED", "length": 369, "reference_go_mf": ["GO:0034038", "GO:0042802"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_cd72f0041c68701d9e1d"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_688_2odq_assembly1", "enzyme_name": "classical-complement-pathway C3/C5 convertase", "ec": ["3.4.21.43"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q5JP69", "alignment_score": 957.0, "observed_coverage": 1.0, "aligned_identity": 0.9979674796747967, "canonical_span": [243, 750], "sequence": "MGPLMVLFCLLFLYPGLADSAPSCPQNVNISGGTFTLSHGWAPGSLLTYSCPQGLYPSPASRLCKSSGQWQTPGATRSLSKAVCKPVRCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDNGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPICRQPYSYDFPEDVAPALGTSFSHMLGATNPTQKTKESLGRKIQIQRSGHLNLYLLLDCSQSVSENDFLIFKESASLMVDRIFSFEINVSVAIITFASEPKVLMSVLNDNSRDMTEVISSLENANYKDHENGTGTNTYAALNSVYLMMNNQMRLLGMETMAWQEIRHAIILLTDGKSNMGGSPKTAVDHIREILNINQKRNDYLDIYAIGVGKLDVDWRELNELGSKKDGERHAFILQDTKALHQVFEHMLDVSKLTDTICGVGNMSANASDQERTPWHVTIKPKSQETCRGALISDQWVLTAAHCFRDGNDHSLWRVNVGDPKSQWGKEFLIEKAVISPGFDVFAKKNQGILEFYGDDIALLKLAQKVKMSTHARPICLPCTMEANLALRRPQGSTCRDHENELLNKQSVPAHFVALNGSKLNINLKMGVEWTSCAEVVSQEKTMFPNLTDVREVVTDQFLCSGTQEDESPCKGESGGAVFLERRFRFFQVGLVSWGLYNPCLGSADKNSRKRAPRSKVPPPRDFHINLFRMQPWLRQHLGDVLNFLPL", "length": 752, "reference_go_mf": ["GO:0004252"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_914bb196cd912f959039"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_689_1r6w_assembly1", "enzyme_name": "o-succinylbenzoate synthase", "ec": ["4.2.1.113"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P29208", "alignment_score": 629.0, "observed_coverage": 0.9937694704049844, "aligned_identity": 0.9968652037617555, "canonical_span": [0, 320], "sequence": "MRSAQVYRWQIPMDAGVVLRDRRLKTRDGLYVCLREGEREGWGEISPLPGFSQETWEEAQSVLLAWVNNWLAGDCELPQMPSVAFGVSCALAELTDTLPQAANYRAAPLCNGDPDDLILKLADMPGEKVAKVKVGLYEAVRDGMVVNLLLEAIPDLHLRLDANRAWTPLKGQQFAKYVNPDYRDRIAFLEEPCKTRDDSRAFARETGIAIAWDESLREPDFAFVAEEGVRAVVIKPTLTGSLEKVREQVQAAHALGLTAVISSSIESSLGLTQLARIAAWLTPDTIPGLDTLDLMQAQQVRRWPGSTLPVVEVDALERLL", "length": 320, "reference_go_mf": ["GO:0016836", "GO:0000287", "GO:0043748"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_a9b98b5352957cb16718"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_68_1ivh_assembly1", "enzyme_name": "isovaleryl-CoA dehydrogenase", "ec": ["1.3.8.4"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P26440", "alignment_score": 774.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [37, 424], "sequence": "MAEMATATRLLGWRVASWRLRPPLAGFVSQRAHSLLPVDDAINGLSEEQRQLRQTMAKFLQEHLAPKAQEIDRSNEFKNLREFWKQLGNLGVLGITAPVQYGGSGLGYLEHVLVMEEISRASGAVGLSYGAHSNLCINQLVRNGNEAQKEKYLPKLISGEYIGALAMSEPNAGSDVVSMKLKAEKKGNHYILNGNKFWITNGPDADVLIVYAKTDLAAVPASRGITAFIVEKGMPGFSTSKKLDKLGMRGSNTCELIFEDCKIPAANILGHENKGVYVLMSGLDLERLVLAGGPLGLMQAVLDHTIPYLHVREAFGQKIGHFQLMQGKMADMYTRLMACRQYVYNVAKACDEGHCTAKDCAGVILYSAECATQVALDGIQCFGGNGYINDFPMGRFLRDAKLYEIGAGTSEVRRLVIGRAFNADFH", "length": 426, "reference_go_mf": ["GO:0008470", "GO:0050660", "GO:0042802", "GO:0070991"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_c6756548a52fc2a4e04f"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_693_2rnf_assembly1", "enzyme_name": "ribonuclease 4", "ec": ["4.6.1.18"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P34096", "alignment_score": 238.0, "observed_coverage": 0.9916666666666667, "aligned_identity": 1.0, "canonical_span": [28, 147], "sequence": "MALQRTHSLLLLLLLTLLGLGLVQPSYGQDGMYQRFLRQHVHPEETGGSDRYCNLMMQRRKMTLYHCKRFNTFIHEDIWNIRSICSTTNIQCKNGKMNCHEGVVKVTDCRDTGSSRAPNCRYRAIASTRRVVIACEGNPQVPVHFDG", "length": 147, "reference_go_mf": ["GO:0003676", "GO:0004522", "GO:0004540"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_bdb5ad9576d2cdc105ab"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_694_1oxa_assembly1", "enzyme_name": "6-deoxyerythronolide B hydroxylase", "ec": ["1.14.15.35"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q00441", "alignment_score": 783.0, "observed_coverage": 0.9975186104218362, "aligned_identity": 0.9825870646766169, "canonical_span": [2, 404], "sequence": "MTTVPDLESDSFHVDWYRTYAELRETAPVTPVRFLGQDAWLVTGYDEAKAALSDLRLSSDPKKKYPGVEVEFPAYLGFPEDVRNYFATNMGTSDPPTHTRLRKLVSQEFTVRRVEAMRPRVEQITAELLDEVGDSGVVDIVDRFAHPLPIKVICELLGVDEKYRGEFGRWSSEILVMDPERAEQRGQAAREVVNFILDLVERRRTEPGDDLLSALIRVQDDDDGRLSADELTSIALVLLLAGFEASVSLIGIGTYLLLTHPDQLALVRRDPSALPNAVEEILRYIAPPETTTRFAAEEVEIGGVAIPQYSTVLVANGAANRDPKQFPDPHRFDVTRDTRGHLSFGQGIHFCMGRPLAKLEGEVALRALFGRFPALSLGIDADDVVWRRSLLLRGIDHLPVRLDG", "length": 404, "reference_go_mf": ["GO:0020037", "GO:0005506", "GO:0004497", "GO:0016705"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_cf50d631c1b1309ed4f5"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_695_2bsx_assembly1", "enzyme_name": "purine-nucleoside phosphorylase", "ec": ["2.4.2.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q8I3X4", "alignment_score": 469.5, "observed_coverage": 0.991701244813278, "aligned_identity": 1.0, "canonical_span": [0, 245], "sequence": "MDNLLRHLKISKEQITPVVLVVGDPGRVDKIKVVCDSYVDLAYNREYKSVECHYKGQKFLCVSHGVGSAGCAVCFEELCQNGAKVIIRAGSCGSLQPDLIKRGDICICNAAVREDRVSHLLIHGDFPAVGDFDVYDTLNKCAQELNVPVFNGISVSSDMYYPNKIIPSRLEDYSKANAAVVEMELATLMVIGTLRKVKTGGILIVDGCPFKWDEGDFDNNLVPHQLENMIKIALGACAKLATKYA", "length": 245, "reference_go_mf": ["GO:0047975", "GO:0004731", "GO:0017061", "GO:0004850"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_8b157d74d30d5eae4069"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "Q8I3X4", "alignment_score": 469.5, "observed_coverage": 0.991701244813278, "aligned_identity": 1.0, "canonical_span": [0, 245], "sequence": "MDNLLRHLKISKEQITPVVLVVGDPGRVDKIKVVCDSYVDLAYNREYKSVECHYKGQKFLCVSHGVGSAGCAVCFEELCQNGAKVIIRAGSCGSLQPDLIKRGDICICNAAVREDRVSHLLIHGDFPAVGDFDVYDTLNKCAQELNVPVFNGISVSSDMYYPNKIIPSRLEDYSKANAAVVEMELATLMVIGTLRKVKTGGILIVDGCPFKWDEGDFDNNLVPHQLENMIKIALGACAKLATKYA", "length": 245, "reference_go_mf": ["GO:0047975", "GO:0004731", "GO:0017061", "GO:0004850"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_8b157d74d30d5eae4069"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_696_1dgk_assembly1", "enzyme_name": "hexokinase (type I)", "ec": ["2.7.1.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P19367", "alignment_score": 1784.0, "observed_coverage": 1.0, "aligned_identity": 0.9955456570155902, "canonical_span": [15, 913], "sequence": "MIAAQLLAYYFTELKDDQVKKIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVSFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSDVRFLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKGAALITAVGVRLRTEASS", "length": 917, "reference_go_mf": ["GO:0005524", "GO:0005536", "GO:0008865", "GO:0004340", "GO:0047931", "GO:0004396", "GO:0019158", "GO:0042834"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_d8e43e82ed200e3bb477"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_697_2hsa_assembly1", "enzyme_name": "12-oxophytodienoate reductase", "ec": ["1.3.1.42"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q9FEW9", "alignment_score": 748.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [10, 384], "sequence": "MASSAQDGNNPLFSPYKMGKFNLSHRVVLAPMTRCRALNNIPQAALGEYYEQRATAGGFLITEGTMISPTSAGFPHVPGIFTKEQVREWKKIVDVVHAKGAVIFCQLWHVGRASHEVYQPAGAAPISSTEKPISNRWRILMPDGTHGIYPKPRAIGTYEISQVVEDYRRSALNAIEAGFDGIEIHGAHGYLIDQFLKDGINDRTDEYGGSLANRCKFITQVVQAVVSAIGADRVGVRVSPAIDHLDAMDSNPLSLGLAVVERLNKIQLHSGSKLAYLHVTQPRYVAYGQTEAGRLGSEEEEARLMRTLRNAYQGTFICSGGYTRELGIEAVAQGDADLVSYGRLFISNPDLVMRIKLNAPLNKYNRKTFYTQDPVVGYTDYPFLQGNGSNGPLSRL", "length": 396, "reference_go_mf": ["GO:0016629", "GO:0010181", "GO:0042802"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_313b937c4430a3fad847"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_699_1bu7_assembly2", "enzyme_name": "cytochrome P450 (BM-3)", "ec": ["1.14.14.1"], "controls": [{"chain": "A", "status": "reference_overlength", "selected": {"accession": "P14779", "alignment_score": 910.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 456], "sequence": "MTIKEMPQPKTFGELKNLPLLNTDKPVQALMKIADELGEIFKFEAPGRVTRYLSSQRLIKEACDESRFDKNLSQALKFVRDFAGDGLFTSWTHEKNWKKAHNILLPSFSQQAMKGYHAMMVDIAVQLVQKWERLNADEHIEVPEDMTRLTLDTIGLCGFNYRFNSFYRDQPHPFITSMVRALDEAMNKLQRANPDDPAYDENKRQFQEDIKVMNDLVDKIIADRKASGEQSDDLLTHMLNGKDPETGEPLDDENIRYQIITFLIAGHETTSGLLSFALYFLVKNPHVLQKAAEEAARVLVDPVPSYKQVKQLKYVGMVLNEALRLWPTAPAFSLYAKEDTVLGGEYPLEKGDELMVLIPQLHRDKTIWGDDVEEFRPERFENPSAIPQHAFKPFGNGQRACIGQQFALHEATLVLGMMLKHFDFEDHTNYELDIKETLTLKPEGFVVKAKSKKIPLGGIPSPSTEQSAKKVRKKAENAHNTPLLVLYGSNMGTAEGTARDLADIAMSKGFAPQVATLDSHAGNLPREGAVLIVTASYNGHPPDNAKQFVDWLDQASADEVKGVRYSVFGCGDKNWATTYQKVPAFIDETLAAKGAENIADRGEADASDDFEGTYEEWREHMWSDVAAYFNLDIENSEDNKSTLSLQFVDSAADMPLAKMHGAFSTNVVASKELQQPGSARSTRHLEIELPKEASYQEGDHLGVIPRNYEGIVNRVTARFGLDASQQIRLEAEEEKLAHLPLAKTVSVEELLQYVELQDPVTRTQLRAMAAKTVCPPHKVELEALLEKQAYKEQVLAKRLTMLELLEKYPACEMKFSEFIALLPSIRPRYYSISSSPRVDEKQASITVSVVSGEAWSGYGEYKGIASNYLAELQEGDTITCFISTPQSEFTLPKDPETPLIMVGPGTGVAPFRGFVQARKQLKEQGQSLGEAHLYFGCRSPHEDYLYQEELENAQSEGIITLHTAFSRMPNQPKTYVQHVMEQDGKKLIELLDQGAHFYICGDGSQMAPAVEATLMKSYADVHQVSEADARLWLQQLEEKGRYAKDVWAG", "length": 1049, "reference_go_mf": ["GO:0070330", "GO:0050660", "GO:0010181", "GO:0020037", "GO:0042802", "GO:0005506", "GO:0003958", "GO:0016712"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_69_1lxa_assembly1", "enzyme_name": "acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase", "ec": ["2.3.1.129"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0A722", "alignment_score": 524.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 262], "sequence": "MIDKSAFVHPTAIVEEGASIGANAHIGPFCIVGPHVEIGEGTVLKSHVVVNGHTKIGRDNEIYQFASIGEVNQDLKYAGEPTRVEIGDRNRIRESVTIHRGTVQGGGLTKVGSDNLLMINAHIAHDCTVGNRCILANNATLAGHVSVDDFAIIGGMTAVHQFCIIGAHVMVGGCSGVAQDVPPYVIAQGNHATPFGVNIEGLKRRGFSREAITAIRNAYKLIYRSGKTLDEVKPEIAELAETYPEVKAFTDFFARSTRGLIR", "length": 262, "reference_go_mf": ["GO:0008780", "GO:0042802"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_b7a61d92308a19ed6916"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_6_2gh5_assembly1", "enzyme_name": "glutathione-disulfide reductase", "ec": ["1.8.1.7"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00390", "alignment_score": 922.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [61, 522], "sequence": "MALLPRALSAGAGPSWRRAARAFRGFLLLLPEPAALTRALSRAMACRQEPQPQGPPPAAGAVASYDYLVIGGGSGGLASARRAAELGARAAVVESHKLGGTCVNVGCVPKKVMWNTAVHSEFMHDHADYGFPSCEGKFNWRVIKEKRDAYVSRLNAIYQNNLTKSHIEIIRGHAAFTSDPKPTIEVSGKKYTAPHILIATGGMPSTPHESQIPGASLGITSDGFFQLEELPGRSVIVGAGYIAVEMAGILSALGSKTSLMIRHDKVLRSFDSMISTNCTEELENAGVEVLKFSQVKEVKKTLSGLEVSMVTAVPGRLPVMTMIPDVDCLLWAIGRVPNTKDLSLNKLGIQTDDKGHIIVDEFQNTNVKGIYAVGDVCGKALLTPVAIAAGRKLAHRLFEYKEDSKLDYNNIPTVVFSHPPIGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKTKCVMKMVCANKEEKVVGIHMQGLGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSSEELVTLR", "length": 522, "reference_go_mf": ["GO:0009055", "GO:0050660", "GO:0004362", "GO:0050661"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_814d7e6114e40802ecf4"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P00390", "alignment_score": 922.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [61, 522], "sequence": "MALLPRALSAGAGPSWRRAARAFRGFLLLLPEPAALTRALSRAMACRQEPQPQGPPPAAGAVASYDYLVIGGGSGGLASARRAAELGARAAVVESHKLGGTCVNVGCVPKKVMWNTAVHSEFMHDHADYGFPSCEGKFNWRVIKEKRDAYVSRLNAIYQNNLTKSHIEIIRGHAAFTSDPKPTIEVSGKKYTAPHILIATGGMPSTPHESQIPGASLGITSDGFFQLEELPGRSVIVGAGYIAVEMAGILSALGSKTSLMIRHDKVLRSFDSMISTNCTEELENAGVEVLKFSQVKEVKKTLSGLEVSMVTAVPGRLPVMTMIPDVDCLLWAIGRVPNTKDLSLNKLGIQTDDKGHIIVDEFQNTNVKGIYAVGDVCGKALLTPVAIAAGRKLAHRLFEYKEDSKLDYNNIPTVVFSHPPIGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKTKCVMKMVCANKEEKVVGIHMQGLGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSSEELVTLR", "length": 522, "reference_go_mf": ["GO:0009055", "GO:0050660", "GO:0004362", "GO:0050661"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_814d7e6114e40802ecf4"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_700_1b5d_assembly2", "enzyme_name": "deoxycytidylate 5-hydroxymethyltransferase", "ec": ["2.1.2.8"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P08773", "alignment_score": 492.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 246], "sequence": "MISDSMTVEEIRLHLGLALKEKDFVVDKTGVKTIEIIGASFVADEPFIFGALNDEYIQRELEWYKSKSLFVKDIPGETPKIWQQVASSKGEINSNYGWAIWSEDNYAQYDMCLAELGQNPDSRRGIMIYTRPSMQFDYNKDGMSDFMCTNTVQYLIRDKKINAVVNMRSNDVVFGFRNDYAWQKYVLDKLVSDLNAGDSTRQYKAGSIIWNVGSLHVYSRHFYLVDHWWKTGETHISKKDYVGKYA", "length": 246, "reference_go_mf": ["GO:0047153"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_61aa10bd4efab241eb3f"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_702_1pjq_assembly1", "enzyme_name": "uroporphyrinogen-III C-methyltransferase", "ec": ["2.1.1.107"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P25924", "alignment_score": 872.5, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 457], "sequence": "MDHLPIFCQLRDRDCLIVGGGDVAERKARLLLEAGARLTVNALTFIPQFTVWANEGMLTLVEGPFDETLLDSCWLAIAATDDDTVNQRVSDAAESRRIFCNVVDAPKAASFIMPSIIDRSPLMVAVSSGGTSPVLARLLREKLESLLPQHLGQVARYAGQLRARVKKQFATMGERRRFWEKFFVNDRLAQSLANADEKAVNATTERLFSEPLDHRGEVVLVGAGPGDAGLLTLKGLQQIQQADIVVYDRLVSDDIMNLVRRDADRVFVGKRAGYHCVPQEEINQILLREAQKGKRVVRLKGGDPFIFGRGGEELETLCHAGIPFSVVPGITAASGCSAYSGIPLTHRDYAQSVRLVTGHLKTGGELDWENLAAEKQTLVFYMGLNQAATIQEKLIAFGMQADMPVALVENGTSVKQRVVHGVLTQLGELAQQVESPALIIVGRVVALRDKLNWFSNH", "length": 457, "reference_go_mf": ["GO:0051287", "GO:0043115", "GO:0004325", "GO:0051266", "GO:0004851"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_019676b75b38ca4570bc"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_703_1vq1_assembly1", "enzyme_name": "peptide chain release factor N5-glutamine methyltransferase", "ec": ["2.1.1.297"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q9WYV8", "alignment_score": 500.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [11, 282], "sequence": "MDTRKNVSGAERKIWSLIRDCSGKLEGVTETSVLEVLLIVSRVLGIRKEDLFLKDLGVSPTEEKRILELVEKRASGYPLHYILGEKEFMGLSFLVEEGVFVPRPETEELVELALELIRKYGIKTVADIGTGSGAIGVSVAKFSDAIVFATDVSSKAVEIARKNAERHGVSDRFFVRKGEFLEPFKEKFASIEMILSNPPYVKSSAHLPKDVLFEPPEALFGGEDGLDFYREFFGRYDTSGKIVLMEIGEDQVEELKKIVSDTVFLKDSAGKYRFLLLNRRSS", "length": 282, "reference_go_mf": ["GO:0003676", "GO:0102559", "GO:0036009"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_617ddd68c076ea912282"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_705_1pp4_assembly1", "enzyme_name": "rhamnogalacturonan acetylesterase", "ec": ["3.1.1.86"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q00017", "alignment_score": 466.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [17, 250], "sequence": "MKTAALAPLFFLPSALATTVYLAGDSTMAKNGGGSGTNGWGEYLASYLSATVVNDAVAGRSARSYTREGRFENIADVVTAGDYVIVEFGHNDGGSLSTDNGRTDCSGTGAEVCYSVYDGVNETILTFPAYLENAAKLFTAKGAKVILSSQTPNNPWETGTFVNSPTRFVEYAELAAEVAGVEYVDHWSYVDSIYETLGNATVNSYFPIDHTHTSPAGAEVVAEAFLKAVVCTGTSLKSVLTTTSFEGTCL", "length": 250, "reference_go_mf": ["GO:0016788"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_707d5e9915eca7aa4578"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_706_1r44_assembly1", "enzyme_name": "D-Ala-D-Ala dipeptidase", "ec": ["3.4.13.22"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q06241", "alignment_score": 404.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 202], "sequence": "MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTYELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRTEMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEAQNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK", "length": 202, "reference_go_mf": ["GO:0160237", "GO:0008237", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_f745dd77779192e2fa07"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_709_1dj1_assembly1", "enzyme_name": "cytochrome-c peroxidase (mono-heme type)", "ec": ["1.11.1.5"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00431", "alignment_score": 573.0, "observed_coverage": 1.0, "aligned_identity": 0.9896907216494846, "canonical_span": [70, 361], "sequence": "MTTAVRLLPSLGRTAHKRSLYLFSAAAAAAAAATFAYSQSQKRSSSSPGGGSNHGWNNWGKAAALASTTPLVHVASVEKGRSYEDFQKVYNAIALKLREDDEYDNYIGYGPVLVRLAWHTSGTWDKHDNTGGSYGGTYRFKKEFNDPSNAGLQNGFKFLEPIHKEFPWISSGDLFSLGGVTAVQEMQGPKIPWRCGRVDTPEDTTPDNGRLPDADKDADYVRTFFQRLNMNDREVVALMGAHALGKTHLKNSGYEGPWGAANNVFTNEFYLNLLNEDWKLEKNDANNEQWDSKSGYMMLPTDYSLIQDPKYLSIVKEYANDQDKFFKDFSKAFEKLLENGITFPKDAPSPFIFKTLEEQGL", "length": 361, "reference_go_mf": ["GO:0004130", "GO:0020037"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_69015ce85d2df834dc23"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_70_1ef8_assembly1", "enzyme_name": "methylmalonyl-CoA decarboxylase", "ec": ["7.2.4.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P52045", "alignment_score": 504.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 261], "sequence": "MSYQYVNVVTINKVAVIEFNYGRKLNALSKVFIDDLMQALSDLNRPEIRCIILRAPSGSKVFSAGHDIHELPSGGRDPLSYDDPLRQITRMIQKFPKPIISMVEGSVWGGAFEMIMSSDLIIAASTSTFSMTPVNLGVPYNLVGIHNLTRDAGFHIVKELIFTASPITAQRALAVGILNHVVEVEELEDFTLQMAHHISEKAPLAIAVIKEELRVLGEAHTMNSDEFERIQGMRRAVYDSEDYQEGMNAFLEKRKPNFVGH", "length": 261, "reference_go_mf": ["GO:0016831", "GO:0004492"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_8ec5c08584cc3b85f555"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_710_1ra0_assembly1", "enzyme_name": "cytosine deaminase (bacterial)", "ec": ["3.5.4.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P25524", "alignment_score": 843.0, "observed_coverage": 1.0, "aligned_identity": 0.9976359338061466, "canonical_span": [4, 427], "sequence": "MSNNALQTIINARLPGEEGLWQIHLQDGKISAIDAQSGVMPITENSLDAEQGLVIPPFVEPHIHLDTTQTAGQPNWNQSGTLFEGIERWAERKALLTHDDVKQRAWQTLKWQIANGIQHVRTHVDVSDATLTALKAMLEVKQEVAPWIDLQIVAFPQEGILSYPNGEALLEEALRLGADVVGAIPHFEFTREYGVESLHKTFALAQKYDRLIDVHCDEIDDEQSRFVETVAALAHHEGMGARVTASHTTAMHSYNGAYTSRLFRLLKMSGINFVANPLVNIHLQGRFDTYPKRRGITRVKEMLESGINVCFGHDDVFDPWYPLGTANMLQVLHMGLHVCQLMGYGQINDGLNLITHHSARTLNLQDYGIAAGNSANLIILPAENGFDALRRQVPVRYSVRGGKVIASTQPAQTTVYLEQPEAIDYKR", "length": 427, "reference_go_mf": ["GO:0004131", "GO:0008198", "GO:0042802", "GO:0035888", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_f7149c5de913f994b201"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_711_2esd_assembly1", "enzyme_name": "glyceraldehyde-3-phosphate dehydrogenase (NADP+)", "ec": ["1.2.1.9"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q59931", "alignment_score": 936.0, "observed_coverage": 1.0, "aligned_identity": 0.9915611814345991, "canonical_span": [1, 475], "sequence": "MTKQYKNYVNGEWKLSENEIKIYEPASGAELGSVPAMSTEEVDYVYASAKKAQPAWRSLSYIERAAYLHKVADILMRDKEKIGAVLSKEVAKGYKSAVSEVVRTAEIINYAAEEGLRMEGEVLEGGSFEAASKKKIAVVRREPVGLVLAISPFNYPVNLAGSKIAPALIAGNVIAFKPPTQGSISGLLLAEAFAEAGLPAGVFNTITGRGSEIGDYIVEHQAVNFINFTGSTGIGERIGKMAGMRPIMLELGGKDSAIVLEDADLELTAKNIIAGAFGYSGQRCTAVKRVLVMESVADELVEKIREKVLALTIGNPEDDADITPLIDTKSADYVEGLINDANDKGAAALTEIKREGNLICPILFDKVTTDMRLAWEEPFGPVLPIIRVTSVEEAIEISNKSEYGLQASIFTNDFPRAFGIAEQLEVGTVHINNKTQRGTDNFPFLGAKKSGAGIQGVKYSIEAMTTVKSVVFDIK", "length": 475, "reference_go_mf": ["GO:0008886", "GO:0047100", "GO:0008911"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_79f8a7699aff0af3e9b8"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_712_1xa8_assembly1", "enzyme_name": "S-(hydroxymethyl)glutathione synthase", "ec": ["4.4.1.22"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q51669", "alignment_score": 388.0, "observed_coverage": 0.9897959183673469, "aligned_identity": 1.0, "canonical_span": [0, 194], "sequence": "MVDTSGVKIHPAVDNGIKPAQPGFAGGTLHCKCSTNPVRVAVRAQTAHNHVCGCTKCWKPEGAIFSQVAVVGRDALEVLEGAEKLEIVNAEAPIQRHRCRDCGVHMYGRIENRDHPFYGLDFVHTELSDEDGWSAPEFAAFVSSIIESGVDPSRMEAIRARLRELGLEPYDALSPPLMDAIATHIAKRSGALAA", "length": 194, "reference_go_mf": ["GO:0051907", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_7230616e9a9beaeea83a"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_714_1fft_assembly1", "enzyme_name": "ubiquinol oxidase (H+-transporting)", "ec": ["7.1.1.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0ABI8", "alignment_score": 1002.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [51, 552], "sequence": "MFGKLSLDAVPFHEPIVMVTIAGIILGGLALVGLITYFGKWTYLWKEWLTSVDHKRLGIMYIIVAIVMLLRGFADAIMMRSQQALASAGEAGFLPPHHYDQIFTAHGVIMIFFVAMPFVIGLMNLVVPLQIGARDVAFPFLNNLSFWFTVVGVILVNVSLGVGEFAQTGWLAYPPLSGIEYSPGVGVDYWIWSLQLSGIGTTLTGINFFVTILKMRAPGMTMFKMPVFTWASLCANVLIIASFPILTVTVALLTLDRYLGTHFFTNDMGGNMMMYINLIWAWGHPEVYILILPVFGVFSEIAATFSRKRLFGYTSLVWATVCITVLSFIVWLHHFFTMGAGANVNAFFGITTMIIAIPTGVKIFNWLFTMYQGRIVFHSAMLWTIGFIVTFSVGGMTGVLLAVPGADFVLHNSLFLIAHFHNVIIGGVVFGCFAGMTYWWPKAFGFKLNETWGKRAFWFWIIGFFVAFMPLYALGFMGMTRRLSQQIDPQFHTMLMIAASGAVLIALGILCLVIQMYVSIRDRDQNRDLTGDPWGGRTLEWATSSPPPFYNFAVVPHVHERDAFWEMKEKGEAYKKPDHYEEIHMPKNSGAGIVIAAFSTIFGFAMIWHIWWLAIVGFAGMIITWIVKSFDEDVDYYVPVAEIEKLENQHFDEITKAGLKNGN", "length": 663, "reference_go_mf": ["GO:0005507", "GO:0009486", "GO:0004129", "GO:0009055", "GO:0020037", "GO:0016682", "GO:0015453", "GO:0015078", "GO:0048039"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_9ae362367c7947b520ee"}, "alternative_alignments": [{"accession": "P0ABJ1", "alignment_score": 8.0, "observed_coverage": 0.013972055888223553, "aligned_identity": 0.7142857142857143, "canonical_span": [48, 55], "length": 315, "reference_go_mf": ["GO:0005507", "GO:0009486", "GO:0004129", "GO:0009055", "GO:0016682", "GO:0015453", "GO:0015078"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, {"accession": "P0ABJ3", "alignment_score": 8.0, "observed_coverage": 0.007984031936127744, "aligned_identity": 1.0, "canonical_span": [194, 198], "length": 204, "reference_go_mf": ["GO:0009486", "GO:0004129", "GO:0009055", "GO:0015453", "GO:0015078"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_716_1im5_assembly1", "enzyme_name": "nicotinamidase", "ec": ["3.5.1.19"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "O58727", "alignment_score": 358.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 180], "sequence": "MPEEALIVVDMQRDFMPGGALPVPEGDKIIPKVNEYIRKFKEKGALIVATRDWHPENHISFRERGGPWPRHCVQNTPGAEFVVDLPEDAVIISKATEPDKEAYSGFEGTDLAKILRGNGVKRVYICGVATEYCVRATALDALKHGFEVYLLRDAVKGIKPEDEERALEEMKSRGIKIVQF", "length": 180, "reference_go_mf": ["GO:0008936"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_d21328d8eed9f652f13e"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_718_2fqq_assembly1", "enzyme_name": "caspase-1", "ec": ["3.4.22.36"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P29466", "alignment_score": 291.0, "observed_coverage": 1.0, "aligned_identity": 0.9931972789115646, "canonical_span": [150, 297], "sequence": "MADKVLKEKRKLFIRSMGEGTINGLLDELLQTRVLNKEEMEKVKRENATVMDKTRALIDSVIPKGAQACQICITYICEEDSYLAGTLGLSADQTSGNYLNMQDSQGVLSSFPAPQAVQDNPAMPTSSGSEGNVKLCSLEEAQRIWKQKSAEIYPIMDKSSRTRLALIICNEEFDSIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRGDSPGVVWFKDSVGVSGNLSLPTTEEFEDDAIKKAHIEKDFIAFCSSTPDNVSWRHPTMGSVFIGRLIEHMQEYACSCDVEEIFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH", "length": 404, "reference_go_mf": ["GO:0050700", "GO:0008656", "GO:0004197", "GO:0019955", "GO:0004175", "GO:0042802", "GO:0019900"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_beec7f48b884ff00dab1"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P29466", "alignment_score": 167.0, "observed_coverage": 1.0, "aligned_identity": 0.9659090909090909, "canonical_span": [316, 404], "sequence": "MADKVLKEKRKLFIRSMGEGTINGLLDELLQTRVLNKEEMEKVKRENATVMDKTRALIDSVIPKGAQACQICITYICEEDSYLAGTLGLSADQTSGNYLNMQDSQGVLSSFPAPQAVQDNPAMPTSSGSEGNVKLCSLEEAQRIWKQKSAEIYPIMDKSSRTRLALIICNEEFDSIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRGDSPGVVWFKDSVGVSGNLSLPTTEEFEDDAIKKAHIEKDFIAFCSSTPDNVSWRHPTMGSVFIGRLIEHMQEYACSCDVEEIFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH", "length": 404, "reference_go_mf": ["GO:0050700", "GO:0008656", "GO:0004197", "GO:0019955", "GO:0004175", "GO:0042802", "GO:0019900"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_beec7f48b884ff00dab1"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_719_1pd2_assembly1", "enzyme_name": "prostaglandin-D synthase", "ec": ["5.3.99.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "O35543", "alignment_score": 398.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 199], "sequence": "MPNYKLLYFNMRGRAEIIRYIFAYLDIKYEDHRIEQADWPKIKPTLPFGKIPVLEVEGLTLHQSLAIARYLTKNTDLAGKTELEQCQVDAVVDTLDDFMSLFPWAEENQDLKERTFNDLLTRQAPHLLKDLDTYLGDKEWFIGNYVTWADFYWDICSTTLLVLKPDLLGIYPRLVSLRNKVQAIPAISAWILKRPQTKL", "length": 199, "reference_go_mf": ["GO:0005509", "GO:0004364", "GO:0000287", "GO:0004667", "GO:0042803"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_6deeb04506da500276fb"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_71_1eug_assembly1", "enzyme_name": "uridine nucleosidase (family I)", "ec": ["3.2.2.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P12295", "alignment_score": 447.0, "observed_coverage": 1.0, "aligned_identity": 0.9955555555555555, "canonical_span": [4, 229], "sequence": "MANELTWHDVLAEEKQQPYFLNTLQTVASERQSGVTIYPPQKDVFNAFRFTELGDVKVVILGQDPYHGPGQAHGLAFSVRPGIAIPPSLLNMYKELENTIPGFTRPNHGYLESWARQGVLLLNTVLTVRAGQAHSHASLGWETFTDKVISLINQHREGVVFLLWGSHAQKKGAIIDKQRHHVLKAPHPSPLSAHRGFFGCNHFVLANQWLEQRGETPIDWMPVLPAESE", "length": 229, "reference_go_mf": ["GO:0004844"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_da41f8bf6987c101744e"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_720_1j2u_assembly1", "enzyme_name": "creatininase", "ec": ["3.5.2.10"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P83772", "alignment_score": 514.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [2, 259], "sequence": "MSKSVFVGELTWKEYEARVAAGDCVLMLPVGALEQHGHHMCMNVDVLLPTAVCKRVAERIGALVMPGLQYGYKSQQKSGGGNHFPGTTSLDGATLTGTVQDIIRELARHGARRLVLMNGHYENSMFIVEGIDLALRELRYAGIQDFKVVVLSYWDFVKDPAVIQQLYPEGFLGWDIEHGGVFETSLMLALYPDLVDLDRVVDHPPATFPPYDVFPVDPARTPAPGTLSSAKTASREKGELILEVCVQGIADAIREEFPPT", "length": 260, "reference_go_mf": ["GO:0047789", "GO:0016811", "GO:0030145", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_16c002c1ec20819d8c05"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_722_1ozh_assembly1", "enzyme_name": "acetolactate synthase (catabolic)", "ec": ["2.2.1.6"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P27696", "alignment_score": 1075.5, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [6, 558], "sequence": "MDKQYPVRQWAHGADLVVSQLEAQGVRQVFGIPGAKIDKVFDSLLDSSIRIIPVRHEANAAFMAAAVGRITGKAGVALVTSGPGCSNLITGMATANSEGDPVVALGGAVKRADKAKQVHQSMDTVAMFSPVTKYAIEVTAPDALAEVVSNAFRAAEQGRPGSAFVSLPQDVVDGPVSGKVLPASGAPQMGAAPDDAIDQVAKLIAQAKNPIFLLGLMASQPENSKALRRLLETSHIPVTSTYQAAGAVNQDNFSRFAGRVGLFNNQAGDRLLQLADLVICIGYSPVEYEPAMWNSGNATLVHIDVLPAYEERNYTPDVELVGDIAGTLNKLAQNIDHRLVLSPQAAEILRDRQHQRELLDRRGAQLNQFALHPLRIVRAMQDIVNSDVTLTVDMGSFHIWIARYLYTFRARQVMISNGQQTMGVALPWAIGAWLVNPERKVVSVSGDGGFLQSSMELETAVRLKANVLHLIWVDNGYNMVAIQEEKKYQRLSGVEFGPMDFKAYAESFGAKGFAVESAEALEPTLRAAMDVDGPAVVAIPVDYRDNPLLMGQLHLSQIL", "length": 559, "reference_go_mf": ["GO:0003984", "GO:0050660", "GO:0000287", "GO:0030976"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_64bb31be549d25459c35"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_723_1s01_assembly1", "enzyme_name": "subtilisin", "ec": ["3.4.21.62"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00782", "alignment_score": 527.0, "observed_coverage": 1.0, "aligned_identity": 0.9817518248175182, "canonical_span": [107, 382], "sequence": "MRGKKVWISLLFALALIFTMAFGSTSSAQAAGKSNGEKKYIVGFKQTMSTMSAAKKKDVISEKGGKVQKQFKYVDAASATLNEKAVKELKKDPSVAYVEEDHVAHAYAQSVPYGVSQIKAPALHSQGYTGSNVKVAVIDSGIDSSHPDLKVAGGASMVPSETNPFQDNNSHGTHVAGTVAALNNSIGVLGVAPSASLYAVKVLGADGSGQYSWIINGIEWAIANNMDVINMSLGGPSGSAALKAAVDKAVASGVVVVAAAGNEGTSGSSSTVGYPGKYPSVIAVGAVDSSNQRASFSSVGPELDVMAPGVSIQSTLPGNKYGAYNGTSMASPHVAGAAALILSKHPNWTNTQVRSSLENTTTKLGDSFYYGKGLINVQAAAQ", "length": 382, "reference_go_mf": ["GO:0004252"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_92e1e61975526bcf2860"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_724_1jhf_assembly1", "enzyme_name": "repressor LexA", "ec": ["3.4.21.88"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0A7C2", "alignment_score": 391.0, "observed_coverage": 1.0, "aligned_identity": 0.9949238578680203, "canonical_span": [1, 198], "sequence": "MKALTARQQEVFDLIRDHISQTGMPPTRAEIAQRLGFRSPNAAEEHLKALARKGVIEIVSGASRGIRLLQEEEEGLPLVGRVAAGEPLLAQQHIEGHYQVDPSLFKPNADFLLRVSGMSMKDIGIMDGDLLAVHKTQDVRNGQVVVARIDDEVTVKRLKKQGNKVELLPENSEFKPIVVDLRQQSFTIEGLAVGVIRNGDWL", "length": 202, "reference_go_mf": ["GO:0003677", "GO:0001217", "GO:0042802", "GO:0043565", "GO:0004252", "GO:0000976"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_29cd607d00d716d70d81"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_725_2acu_assembly1", "enzyme_name": "aldehyde reductase", "ec": ["1.1.1.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P15121", "alignment_score": 627.0, "observed_coverage": 1.0, "aligned_identity": 0.9968253968253968, "canonical_span": [1, 316], "sequence": "MASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALLSCTSHKDYPFHEEF", "length": 316, "reference_go_mf": ["GO:0004032", "GO:0052650", "GO:0047655", "GO:0047681", "GO:0032866", "GO:0009055", "GO:0043795", "GO:0047956", "GO:0032867", "GO:0047939", "GO:0036130", "GO:0001758"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_ea6689b6c8edb306fc5d"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_727_1l7n_assembly1", "enzyme_name": "phosphoserine phosphatase", "ec": ["3.1.3.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q58989", "alignment_score": 402.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [2, 211], "sequence": "MEKKKKLILFDFDSTLVNNETIDEIAREAGVEEEVKKITKEAMEGKLNFEQSLRKRVSLLKDLPIEKVEKAIKRITPTEGAEETIKELKNRGYVVAVVSGGFDIAVNKIKEKLGLDYAFANRLIVKDGKLTGDVEGEVLKENAKGEILEKIAKIEGINLEDTVAVGDGANDISMFKKAGLKIAFCAKPILKEKADICIEKRDLREILKYIK", "length": 211, "reference_go_mf": ["GO:0036424", "GO:0000287"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_1b783ad3977c22dc636e"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_728_1tht_assembly1", "enzyme_name": "myristoyl-ACP-specific thioesterase", "ec": ["2.3.1.-"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P05521", "alignment_score": 572.5, "observed_coverage": 1.0, "aligned_identity": 0.9931972789115646, "canonical_span": [3, 305], "sequence": "MNNQCKTIAHVLRVNNGQELHVWETPPKENVPFKNNTILIASGFARRMDHFAGLAEYLSENGFHVFRYDSLHHVGLSSGSIDEFTMTTGKNSLCTVYHWLQTKGTQNIGLIAASLSARVAYEVISDLELSFLITAVGVVNLRDTLEKALGFDYLSLPIDELPNDLDFEGHKLGSEVFVRDCFEHHWDTLDSTLDKVANTSVPLIAFTANNDDWVKQEEVYDMLAHIRTGHCKLYSLLGSSHDLGENLVVLRNFYQSVTKAAIAMDGGSLEIDVDFIEPDFEQLTIATVNERRLKAEIESRTPEMA", "length": 305, "reference_go_mf": ["GO:0016747"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_d2b8ea7895ea704b2e62"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_729_2f9z_assembly1", "enzyme_name": "protein-glutamate methylesterase (CheD)", "ec": ["3.1.1.61"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q9X005", "alignment_score": 296.0, "observed_coverage": 0.987012987012987, "aligned_identity": 1.0, "canonical_span": [0, 157], "sequence": "MKKVIGIGEYAVMKNPGVIVTLGLGSCVAVCMRDPVAKVGAMAHVMLPDSGGKTDKPGKYADTAVKTLVEELKKMGAKVERLEAKIAGGASMFESKGMNIGARNVEAVKKHLKDFGIKLLAEDTGGNRARSVEYNIETGKLLVRKVGGGEQLEIKEI", "length": 157, "reference_go_mf": ["GO:0008984", "GO:0050568"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_0512aa13c28630436fa0"}, "alternative_alignments": [{"accession": "Q9X006", "alignment_score": 9.0, "observed_coverage": 0.03896103896103896, "aligned_identity": 0.8333333333333334, "canonical_span": [15, 21], "length": 205, "reference_go_mf": ["GO:0004721"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_72_2fua_assembly1", "enzyme_name": "L-fuculose-phosphate aldolase", "ec": ["4.1.2.17"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0AB87", "alignment_score": 420.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 210], "sequence": "MERNKLARQIIDTCLEMTRLGLNQGTAGNVSVRYQDGMLITPTGIPYEKLTESHIVFIDGNGKHEEGKLPSSEWRFHMAAYQSRPDANAVVHNHAVHCTAVSILNRSIPAIHYMIAAAGGNSIPCAPYATFGTRELSEHVALALKNRKATLLQHHGLIACEVNLEKALWLAHEVEVLAQLYLTTLAITDPVPVLSDEEIAVVLEKFKTYGLRIEE", "length": 215, "reference_go_mf": ["GO:0016832", "GO:0008738", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_3f1dabf12f562dec58c8"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P0AB87", "alignment_score": 420.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 210], "sequence": "MERNKLARQIIDTCLEMTRLGLNQGTAGNVSVRYQDGMLITPTGIPYEKLTESHIVFIDGNGKHEEGKLPSSEWRFHMAAYQSRPDANAVVHNHAVHCTAVSILNRSIPAIHYMIAAAGGNSIPCAPYATFGTRELSEHVALALKNRKATLLQHHGLIACEVNLEKALWLAHEVEVLAQLYLTTLAITDPVPVLSDEEIAVVLEKFKTYGLRIEE", "length": 215, "reference_go_mf": ["GO:0016832", "GO:0008738", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_3f1dabf12f562dec58c8"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_731_1mt5_assembly1", "enzyme_name": "fatty acid amide hydrolase", "ec": ["3.5.1.99"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P97612", "alignment_score": 1074.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [36, 573], "sequence": "MVLSEVWTTLSGVSGVCLACSLLSAAVVLRWTGRQKARGAATRARQKQRASLETMDKAVQRFRLQNPDLDSEALLTLPLLQLVQKLQSGELSPEAVFFTYLGKAWEVNKGTNCVTSYLTDCETQLSQAPRQGLLYGVPVSLKECFSYKGHDSTLGLSLNEGMPSESDCVVVQVLKLQGAVPFVHTNVPQSMLSFDCSNPLFGQTMNPWKSSKSPGGSSGGEGALIGSGGSPLGLGTDIGGSIRFPSAFCGICGLKPTGNRLSKSGLKGCVYGQTAVQLSLGPMARDVESLALCLKALLCEHLFTLDPTVPPLPFREEVYRSSRPLRVGYYETDNYTMPSPAMRRALIETKQRLEAAGHTLIPFLPNNIPYALEVLSAGGLFSDGGRSFLQNFKGDFVDPCLGDLILILRLPSWFKRLLSLLLKPLFPRLAAFLNSMRPRSAEKLWKLQHEIEMYRQSVIAQWKAMNLDVLLTPMLGPALDLNTPGRATGAISYTVLYNCLDFPAGVVPVTTVTAEDDAQMELYKGYFGDIWDIILKKAMKNSVGLPVAVQCVALPWQEELCLRFMREVEQLMTPQKQPS", "length": 579, "reference_go_mf": ["GO:0004040", "GO:0106435", "GO:0017064", "GO:0016788", "GO:0042802", "GO:0008289", "GO:0047372", "GO:0047412", "GO:0005543"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_b1906431293a15289fd4"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_732_1xs1_assembly1", "enzyme_name": "dCTP deaminase", "ec": ["3.5.4.13"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P28248", "alignment_score": 386.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 193], "sequence": "MRLCDRDIEAWLDEGRLSINPRPPVERINGATVDVRLGNKFRTFRGHTAAFIDLSGPKDEVSAALDRVMSDEIVLDEGEAFYLHPGELALAVTLESVTLPADLVGWLDGRSSLARLGLMVHVTAHRIDPGWSGCIVLEFYNSGKLPLALRPGMLIGALSFEPLSGPAVRPYNRREDAKYRNQQGAVASRIDKD", "length": 193, "reference_go_mf": ["GO:0008829", "GO:0042802"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_6b681aa96c5143237193"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P28248", "alignment_score": 386.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 193], "sequence": "MRLCDRDIEAWLDEGRLSINPRPPVERINGATVDVRLGNKFRTFRGHTAAFIDLSGPKDEVSAALDRVMSDEIVLDEGEAFYLHPGELALAVTLESVTLPADLVGWLDGRSSLARLGLMVHVTAHRIDPGWSGCIVLEFYNSGKLPLALRPGMLIGALSFEPLSGPAVRPYNRREDAKYRNQQGAVASRIDKD", "length": 193, "reference_go_mf": ["GO:0008829", "GO:0042802"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_6b681aa96c5143237193"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_733_1zoi_assembly1", "enzyme_name": "esterase", "ec": ["3.1.1.-"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q3HWU8", "alignment_score": 550.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 276], "sequence": "MSYVTTKDGVQIFYKDWGPRDAPVIHFHHGWPLSADDWDAQLLFFLAHGYRVVAHDRRGHGRSSQVWDGHDMDHYADDVAAVVAHLGIQGAVHVGHSTGGGEVVRYMARHPEDKVAKAVLIAAVPPLMVQTPGNPGGLPKSVFDGFQAQVASNRAQFYRDVPAGPFYGYNRPGVEASEGIIGNWWRQGMIGSAKAHYDGIVAFSQTDFTEDLKGIQQPVLVMHGDDDQIVPYENSGVLSAKLLPNGALKTYKGYPHGMPTTHADVINADLLAFIRS", "length": 276, "reference_go_mf": [], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_641bcf13f6c518a138a4"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_735_1ehk_assembly1", "enzyme_name": "cytochrome-c oxidase (BA3 type)", "ec": ["1.9.3.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q5SJ79", "alignment_score": 1080.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [13, 562], "sequence": "MAVRASEISRVYEAYPEKKATLYFLVLGFLALIVGSLFGPFQALNYGNVDAYPLLKRLLPFVQSYYQGLTLHGVLNAIVFTQLFAQAIMVYLPARELNMRPNMGLMWLSWWMAFIGLVVAALPLLANEATVLYTFYPPLKGHWAFYLGASVFVLSTWVSIYIVLDLWRRWKAANPGKVTPLVTYMAVVFWLMWFLASLGLVLEAVLFLLPWSFGLVEGVDPLVARTLFWWTGHPIVYFWLLPAYAIIYTILPKQAGGKLVSDPMARLAFLLFLLLSTPVGFHHQFADPGIDPTWKMIHSVLTLFVAVPSLMTAFTVAASLEFAGRLRGGRGLFGWIRALPWDNPAFVAPVLGLLGFIPGGAGGIVNASFTLDYVVHNTAWVPGHFHLQVASLVTLTAMGSLYWLLPNLTGKPISDAQRRLGLAVVWLWFLGMMIMAVGLHWAGLLNVPRRAYIAQVPDAYPHAAVPMVFNVLAGIVLLVALLLFIYGLFSVLLSRERKPELAEAPLPFAEVISGPEDRRLVLAMDRIGFWFAVAAILVVLAYGPTLVQLFGHLNPVPGWRLW", "length": 562, "reference_go_mf": ["GO:0004129", "GO:0020037"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_044c987865892a2897f3"}, "alternative_alignments": [{"accession": "Q5SJ80", "alignment_score": 9.0, "observed_coverage": 0.011029411764705883, "aligned_identity": 0.8333333333333334, "canonical_span": [133, 139], "length": 168, "reference_go_mf": ["GO:0005507", "GO:0004129"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, {"accession": "P82543", "alignment_score": 8.0, "observed_coverage": 0.007352941176470588, "aligned_identity": 1.0, "canonical_span": [20, 24], "length": 34, "reference_go_mf": ["GO:0004129"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}, {"chain": "B", "status": "assigned", "selected": {"accession": "Q5SJ80", "alignment_score": 332.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [2, 168], "sequence": "MVDEHKAHKAILAYEKGWLAFSLAMLFVFIALIAYTLATHTAGVIPAGKLERVDPTTVRQEGPWADPAQAVVQTGPNQYTVYVLAFAFGYQPNPIEVPQGAEIVFKITSPDVIHGFHVEGTNINVEVLPGEVSTVRYTFKRPGEYRIICNQYCGLGHQNMFGTIVVKE", "length": 168, "reference_go_mf": ["GO:0005507", "GO:0004129"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_13fb0dcb988dfb81e7db"}, "alternative_alignments": [{"accession": "Q5SJ79", "alignment_score": 9.0, "observed_coverage": 0.03614457831325301, "aligned_identity": 0.8333333333333334, "canonical_span": [129, 135], "length": 562, "reference_go_mf": ["GO:0004129", "GO:0020037"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, {"accession": "P82543", "alignment_score": 7.0, "observed_coverage": 0.030120481927710843, "aligned_identity": 0.8, "canonical_span": [5, 10], "length": 34, "reference_go_mf": ["GO:0004129"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_736_1x9h_assembly1", "enzyme_name": "mannose-6-phosphate isomerase", "ec": ["5.3.1.8"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q8ZWV0", "alignment_score": 602.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 302], "sequence": "MSQLLQDYLNWENYILRRVDFPTSYVVEGEVVRIEAMPRLYISGMGGSGVVADLIRDFSLTWNWEVEVIAVKDYFLKARDGLLIAVSYSGNTIETLYTVEYAKRRRIPAVAITTGGRLAQMGVPTVIVPKASAPRAALPQLLTAALHVVAKVYGIDVKIPEGLEPPNEALIHKLVEEFQKRPTIIAAESMRGVAYRVKNEFNENAKIEPSVEILPEAHHNWIEGSERAVVALTSPHIPKEHQERVKATVEIVGGSIYAVEMHPKGVLSFLRDVGIASVKLAEIRGVNPLATPRIDALKRRLQ", "length": 302, "reference_go_mf": ["GO:0097367", "GO:0004347", "GO:0004476"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_9941b430692ec33010d3"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "Q8ZWV0", "alignment_score": 602.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 302], "sequence": "MSQLLQDYLNWENYILRRVDFPTSYVVEGEVVRIEAMPRLYISGMGGSGVVADLIRDFSLTWNWEVEVIAVKDYFLKARDGLLIAVSYSGNTIETLYTVEYAKRRRIPAVAITTGGRLAQMGVPTVIVPKASAPRAALPQLLTAALHVVAKVYGIDVKIPEGLEPPNEALIHKLVEEFQKRPTIIAAESMRGVAYRVKNEFNENAKIEPSVEILPEAHHNWIEGSERAVVALTSPHIPKEHQERVKATVEIVGGSIYAVEMHPKGVLSFLRDVGIASVKLAEIRGVNPLATPRIDALKRRLQ", "length": 302, "reference_go_mf": ["GO:0097367", "GO:0004347", "GO:0004476"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_9941b430692ec33010d3"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_737_1xrs_assembly1", "enzyme_name": "beta-lysine 5,6-aminomutase", "ec": ["5.4.3.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "E3PRJ5", "alignment_score": 1030.0, "observed_coverage": 0.998062015503876, "aligned_identity": 1.0, "canonical_span": [4, 519], "sequence": "MISVESKLNLDFNLVEKARAKAKAIAIDTQEFIEKHTTVTVERAVCRLLGIDGVDTDEVPLPNIVVDHIKENNGLNLGAAMYIANAVLNTGKTPQEIAQAISAGELDLTKLPMKDLFEVKTKALSMAKETVEKIKNNRSIRESRFEEYGDKSGPLLYVIVATGNIYEDITQAVAAAKQGADVIAVIRTTGQSLLDYVPYGATTEGFGGTYATQENFRLMREALDKVGAEVGKYIRLCNYCSGLCMPEIAAMGAIERLDVMLNDALYGILFRDINMQRTMIDQNFSRIINGFAGVIINTGEDNYLTTADAFEEAHTVLASQFINEQFALLAGLPEEQMGLGHAFEMDPELKNGFLYELSQAQMAREIFPKAPLKYMPPTKFMTGNIFKGHIQDALFNMVTIMTNQRIHLLGMLTEALHTPFMSDRALSIENAQYIFNNMESISEEIQFKEDGLIQKRAGFVLEKANELLEEIEQLGLFDTLEKGIFGGVKRPKDGGKGLNGVVSKDENYYNPFVELMLNK", "length": 519, "reference_go_mf": ["GO:0031419", "GO:0047826"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_b78503af2b79f72faf7e"}, "alternative_alignments": [{"accession": "E3PRJ4", "alignment_score": 9.0, "observed_coverage": 0.011627906976744186, "aligned_identity": 0.8333333333333334, "canonical_span": [112, 118], "length": 262, "reference_go_mf": ["GO:0031419", "GO:0047826", "GO:0046872", "GO:0046983"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}, {"chain": "B", "status": "assigned", "selected": {"accession": "E3PRJ4", "alignment_score": 410.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [32, 261], "sequence": "MSSGLYSMEKKEFDKVLDLERVKPYGDTMNDGKVQLSFTLPLKNNERSAEAAKQIALKMGLEEPSVVMQQSLDEEFTFFVVYGNFVQSVNYNEIHVEAVNSEILSMEETDEYIKENIGRKIVVVGASTGTDAHTVGIDAIMNMKGYAGHYGLERYEMIDAYNLGSQVANEDFIKKAVELEADVLLVSQTVTQKNVHIQNMTHLIELLEAEGLRDRFVLLCGGPRINNEIAKELGYDAGFGPGRFADDVATFAVKTLNDRMNS", "length": 262, "reference_go_mf": ["GO:0031419", "GO:0047826", "GO:0046872", "GO:0046983"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_520fb531ffdad4e08760"}, "alternative_alignments": [{"accession": "E3PRJ5", "alignment_score": 9.0, "observed_coverage": 0.02830188679245283, "aligned_identity": 0.8333333333333334, "canonical_span": [174, 180], "length": 519, "reference_go_mf": ["GO:0031419", "GO:0047826"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_738_1o98_assembly1", "enzyme_name": "phosphoglycerate mutase (2,3-bisphosphoglycerate-independent)", "ec": ["5.4.2.12"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q9X519", "alignment_score": 1012.0, "observed_coverage": 1.0, "aligned_identity": 0.9960707269155207, "canonical_span": [1, 510], "sequence": "MSKKPVALIILDGFALRDETYGNAVAQANKPNFDRYWNEYPHTTLKACGEAVGLPEGQMGNSEVGHLNIGAGRIVYQSLTRINIAIREGEFDRNETFLAAMNHVKQHGTSLHLFGLLSDGGVHSHIHHLYALLRLAAKEGVKRVYIHGFLDGRDVGPQTAPQYIKELQEKIKEYGVGEIATLSGRYYSMDRDKRWDRVEKAYRAMVYGEGPTYRDPLECIEDSYKHGIYDEFVLPSVIVREDGRPVATIQDNDAIIFYNFRPDRAIQISNTFTNEDFREFDRGPKHPKHLFFVCLTHFSETVKGYVAFKPTNLDNTIGEVLSQHGLRQLRIAETEKYPHVTFFMSGGREEKFPGEDRILINSPKVPTYDLKPEMSAYEVTDALLKEIEADKYDAIILNYANPDMVGHSGKLEPTIKAVEAVDECLGKVVDAILAKGGIAIITADHGNADEVLTPDGKPQTAHTTNPVPVIVTKKGIKLRDGGILGDLAPTMLDLLGLPQPKEMTGKSLIVK", "length": 511, "reference_go_mf": ["GO:0030145", "GO:0004619"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_dbeab33ed996fa35d643"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_739_1knp_assembly1", "enzyme_name": "L-aspartate oxidase", "ec": ["1.4.3.16"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P10902", "alignment_score": 1052.0, "observed_coverage": 1.0, "aligned_identity": 0.996219281663516, "canonical_span": [4, 533], "sequence": "MNTLPEHSCDVLIIGSGAAGLSLALRLADQHQVIVLSKGPVTEGSTFYAQGGIAAVFDETDSIDSHVEDTLIAGAGICDRHAVEFVASNARSCVQWLIDQGVLFDTHIQPNGEESYHLTREGGHSHRRILHAADATGREVETTLVSKALNHPNIRVLERSNAVDLIVSDKIGLPGTRRVVGAWVWNRNKETVETCHAKAVVLATGGASKVYQYTTNPDISSGDGIAMAWRAGCRVANLEFNQFHPTALYHPQARNFLLTEALRGEGAYLKRPDGTRFMPDFDERGELAPRDIVARAIDHEMKRLGADCMFLDISHKPADFIRQHFPMIYEKLLGLGIDLTQEPVPIVPAAHYTCGGVMVDDHGRTDVEGLYAIGEVSYTGLHGANRMASNSLLECLVYGWSAAEDITRRMPYAHDISTLPPWDESRVENPDERVVIQHNWHELRLFMWDYVGIVRTTKRLERALRRITMLQQEIDEYYAHFRVSNNLLELRNLVQVAELIVRCAMMRKESRGLHFTLDYPELLTHSGPSILSPGNHYINR", "length": 540, "reference_go_mf": ["GO:0050660", "GO:0008734"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_d8b75a12626a7e003801"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_73_1dco_assembly1", "enzyme_name": "4a-hydroxytetrahydrobiopterin dehydratase", "ec": ["4.2.1.96"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P61459", "alignment_score": 198.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [5, 104], "sequence": "MAGKAHRLSAEERDQLLPNLRAVGWNELEGRDAIFKQFHFKDFNRAFGFMTRVALQAEKLDHHPEWFNVYNKVHITLSTHECAGLSERDINLASFIEQVAVSMT", "length": 104, "reference_go_mf": ["GO:0008124", "GO:0042802", "GO:0004505", "GO:0003713"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_cf1f213aba8456cec5fb"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_740_1v04_assembly1", "enzyme_name": "arylesterase", "ec": ["3.1.1.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P27170", "alignment_score": 558.5, "observed_coverage": 1.0, "aligned_identity": 0.9036144578313253, "canonical_span": [15, 355], "sequence": "MAKLTALTLLGLGLALFDGQKSSFQTRFNVHREVTPVELPNCNLVKGIDNGSEDLEILPNGLAFISAGLKYPGIMSFDPDKPGKILLMDLNEKDPVVLELSITGSTFDLSSFNPHGISTFTDEDNIVYLMVVNHPDSKSTVELFKFQEKEKSLLHLKTIRHKLLPSVNDIVAVGPEHFYATNDHYFIDPYLKSWEMHLGLAWSFVTYYSPNDVRVVAEGFDFANGINISPDGKYVYIAELLAHKIHVYEKHANWTLTPLKSLDFNTLVDNISVDPVTGDLWVGCHPNGMRIFYYDPKNPPASEVLRIQDILSKEPKVTVAYAENGTVLQGSTVAAVYKGKMLVGTVFHKALYCELSQAN", "length": 359, "reference_go_mf": ["GO:0102007", "GO:0016209", "GO:0004063", "GO:0004064", "GO:0005509"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_51e85989cea53b5927fa"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_741_1kae_assembly1", "enzyme_name": "histidinol dehydrogenase", "ec": ["1.1.1.23"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P06988", "alignment_score": 818.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 434], "sequence": "MSFNTIIDWNSCTAEQQRQLLMRPAISASESITRTVNDILDNVKARGDEALREYSAKFDKTTVTALKVSAEEIAAASERLSDELKQAMAVAVKNIETFHTAQKLPPVDVETQPGVRCQQVTRPVASVGLYIPGGSAPLFSTVLMLATPASIAGCKKVVLCSPPPIADEILYAAQLCGVQDVFNVGGAQAIAALAFGTESVPKVDKIFGPGNAFVTEAKRQVSQRLDGAAIDMPAGPSEVLVIADSGATPDFVASDLLSQAEHGPDSQVILLTPAADMARRVAEAVERQLAELPRAETARQALNASRLIVTKDLAQCVEISNQYGPEHLIIQTRNARELVDSITSAGSVFLGDWSPESAGDYASGTNHVLPTYGYTATCSSLGLADFQKRMTVQELSKEGFSALASTIETLAAAERLTAHKNAVTLRVNALKEQA", "length": 434, "reference_go_mf": ["GO:0004399", "GO:0030145", "GO:0046872", "GO:0051287", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_e5d62d34191bb5df4db9"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P06988", "alignment_score": 818.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 434], "sequence": "MSFNTIIDWNSCTAEQQRQLLMRPAISASESITRTVNDILDNVKARGDEALREYSAKFDKTTVTALKVSAEEIAAASERLSDELKQAMAVAVKNIETFHTAQKLPPVDVETQPGVRCQQVTRPVASVGLYIPGGSAPLFSTVLMLATPASIAGCKKVVLCSPPPIADEILYAAQLCGVQDVFNVGGAQAIAALAFGTESVPKVDKIFGPGNAFVTEAKRQVSQRLDGAAIDMPAGPSEVLVIADSGATPDFVASDLLSQAEHGPDSQVILLTPAADMARRVAEAVERQLAELPRAETARQALNASRLIVTKDLAQCVEISNQYGPEHLIIQTRNARELVDSITSAGSVFLGDWSPESAGDYASGTNHVLPTYGYTATCSSLGLADFQKRMTVQELSKEGFSALASTIETLAAAERLTAHKNAVTLRVNALKEQA", "length": 434, "reference_go_mf": ["GO:0004399", "GO:0030145", "GO:0046872", "GO:0051287", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_e5d62d34191bb5df4db9"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_742_1qz9_assembly1", "enzyme_name": "kynureninase", "ec": ["3.7.1.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P83788", "alignment_score": 808.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 405], "sequence": "MTTRNDCLALDAQDSLAPLRQQFALPEGVIYLDGNSLGARPVAALARAQAVIAEEWGNGLIRSWNSAGWRDLSERLGNRLATLIGARDGEVVVTDTTSINLFKVLSAALRVQATRSPERRVIVTETSNFPTDLYIAEGLADMLQQGYTLRLVDSPEELPQAIDQDTAVVMLTHVNYKTGYMHDMQALTALSHECGALAIWDLAHSAGAVPVDLHQAGADYAIGCTYKYLNGGPGSQAFVWVSPQLCDLVPQPLSGWFGHSRQFAMEPRYEPSNGIARYLCGTQPITSLAMVECGLDVFAQTDMASLRRKSLALTDLFIELVEQRCAAHELTLVTPREHAKRGSHVSFEHPEGYAVIQALIDRGVIGDYREPRIMRFGFTPLYTTFTEVWDAVQILGEILDRKTWAQAQFQVRHSVT", "length": 416, "reference_go_mf": ["GO:0030429", "GO:0030170"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_e9eb262e3ebd4467abae"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_743_1gqg_assembly1", "enzyme_name": "quercetin 2,3-dioxygenase", "ec": ["1.13.11.24"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q7SIC2", "alignment_score": 653.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [2, 350], "sequence": "DTSSLIVEDAPDHVRPYVIRHYSHARAVTVDTQLYRFYVTGPSSGYAFTLMGTNAPHSDALGVLPHIHQKHYENFYCNKGSFQLWAQSGNETQQTRVLSSGDYGSVPRNVTHTFQIQDPDTEMTGVIVPGGFEDLFYYLGTNATDTTHTPYIPSSSDSSSTTGPDSSTISTLQSFDVYAELSFTPRTDTVNGTAPANTVWHTGANALASTAGDPYFIANGWGPKYLNSQYGYQIVAPFVTATQAQDTNYTLSTISMSTTPSTVTVPTWSFPGACAFQVQEGRVVVQIGDYAATELGSGDVAFIPGGVEFKYYSEAYFSKVLFVSSGSDGLDQNLVNGGEEWSSVSFPADW", "length": 350, "reference_go_mf": ["GO:0008127"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_06a2d356d873af630545"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_748_1j7g_assembly1", "enzyme_name": "D-aminoacyl-tRNA deacylase", "ec": ["3.1.1.96"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P44814", "alignment_score": 288.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 144], "sequence": "MIALIQRVSQAKVDVKGETIGKIGKGLLVLLGVEKEDNREKADKLAEKVLNYRIFSDENDKMNLNVQQAQGELLIVSQFTLAADTQKGLRPSFSKGASPALANELYEYFIQKCAEKLPVSTGQFAADMQVSLTNDGPVTFWLNV", "length": 144, "reference_go_mf": ["GO:0051500", "GO:0106026", "GO:0043908", "GO:0000049"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_3eb1382ba9e006007233"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_74_1bs1_assembly1", "enzyme_name": "dethiobiotin synthase", "ec": ["6.3.3.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P13000", "alignment_score": 448.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 225], "sequence": "MSKRYFVTGTDTEVGKTVASCALLQAAKAAGYRTAGYKPVASGSEKTPEGLRNSDALALQRNSSLQLDYATVNPYTFAEPTSPHIISAQEGRPIESLVMSAGLRALEQQADWVLVEGAGGWFTPLSDTFTFADWVTQEQLPVILVVGVKLGCINHAMLTAQVIQHAGLTLAGWVANDVTPPGKRHAEYMTTLTRMIPAPLLGEIPWLAENPENAATGKYINLALL", "length": 225, "reference_go_mf": ["GO:0005524", "GO:0004141", "GO:0000287", "GO:0042803"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_9c9b1d03f30eb99fad46"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_750_1u8v_assembly1", "enzyme_name": "4-hydroxybutanoyl-CoA dehydratase", "ec": ["4.2.1.120"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P55792", "alignment_score": 977.0, "observed_coverage": 1.0, "aligned_identity": 0.9979591836734694, "canonical_span": [0, 490], "sequence": "MLMTAEQYIESLRKLNTRVYMFGEKIENWVDHPMIRPSINCVAMTYELAQDPQYADLMTTKSNLIGKTINRFANLHQSTDDLRKKVKMQRLLGQKTASCFQRCVGMDAFNAVFSTTYEIDQKYGTNYHKNFTEYLKYIQENDLIVDGAMTDPKGDRGLAPSAQKDPDLFLRIVEKREDGIVVRGAKAHQTGSINSHEHIIMPTIAMTEADKDYAVSFACPSDADGLFMIYGRQSCDTRKMEEGADIDLGNKQFGGQEALVVFDNVFIPNDRIFLCQEYDFAGMMVERFAGYHRQSYGGCKVGVGDVVIGAAALAADYNGAQKASHVKDKLIEMTHLNETLYCCGIACSAEGYPTAAGNYQIDLLLANVCKQNITRFPYEIVRLAEDIAGGLMVTMPSEADFKSETVVGRDGETIGDFCNKFFAAAPTCTTEERMRVLRFLENICLGASAVGYRTESMHGAGSPQAQRIMIARQGNINAKKELAKAIAGIK", "length": 490, "reference_go_mf": ["GO:0043721", "GO:0016627", "GO:0050393"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_f553d60fdbea448abff0"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_751_1tz3_assembly1", "enzyme_name": "CDP-diacylglycerol diphosphatase", "ec": ["3.6.1.26"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q8ZKR2", "alignment_score": 557.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [4, 310], "sequence": "MKAMNKVWVIGDASVDLVPEKQNSYLKCPGGASANVGVCVARLGGECGFIGCLGDDDAGRFLRQVFQDNGVDVTFLRLDADLTSAVLIVNLTADGERSFTYLVHPGADTYVSPQDLPPFRQYEWFYFSSIGLTDRPAREACLEGARRMREAGGYVLFDVNLRSKMWGNTDEIPELIARSAALASICKVSADELCQLSGASHWQDARYYLRDLGCDTTIISLGADGALLITAEGEFHFPAPRVDVVDTTGAGDAFVGGLLFTLSRANCWDHALLAEAISNANACGAMAVTAKGAMTALPFPDQLNTFLSSHSLAQAMTVK", "length": 319, "reference_go_mf": ["GO:0008865"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_d18fd64734a995d42c48"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_752_1vie_assembly1", "enzyme_name": "dihydrofolate reductase (type II)", "ec": ["1.5.1.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00383", "alignment_score": 120.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [18, 78], "sequence": "MERSSNEVSNPVAGNFVFPSNATFGMGDRVRKKSGAAWQGQIVGWYCTNLTPEGYAVESEAHPGSVQIYPVAALERIN", "length": 78, "reference_go_mf": ["GO:0004146"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_1aee1c7de7c67f5ba486"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_754_1j53_assembly1", "enzyme_name": "3'-5' exonuclease", "ec": ["3.1.11.-"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P03007", "alignment_score": 348.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [6, 180], "sequence": "MSTAITRQIVLDTETTGMNQIGAHYEGHKIIEIGAVEVVNRRLTGNNFHVYLKPDRLVDPEAFGVHGIADEFLLDKPTFAEVADEFMDYIRGAELVIHNAAFDIGFMDYEFSLLKRDIPKTNTFCKVTDSLAVARKMFPGKRNSLDALCARYEIDNSKRTLHGALLDAQILAEVYLAMTGGQTSMAFAMEGETQQQQGEATIQRIVRQASKLRVVFATDEEIAAHEARLDLVQKKGGSCLWRA", "length": 243, "reference_go_mf": ["GO:0008408", "GO:0003677", "GO:0003887", "GO:0004527"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_03e0a0f116d670a232e9"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_756_1zrz_assembly1", "enzyme_name": "protein kinase C", "ec": ["2.7.11.13"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P41743", "alignment_score": 577.0, "observed_coverage": 1.0, "aligned_identity": 0.9935483870967742, "canonical_span": [248, 588], "sequence": "MPTQRDSSTMSHTVAGGGSGDHSHQVRVKAYYRGDIMITHFEPSISFEGLCNEVRDMCSFDNEQLFTMKWIDEEGDPCTVSSQLELEEAFRLYELNKDSELLIHVFPCVPERPGMPCPGEDKSIYRRGARRWRKLYCANGHTFQAKRFNRRAHCAICTDRIWGLGRQGYKCINCKLLVHKKCHKLVTIECGRHSLPQEPVMPMDQSSMHSDHAQTVIPYNPSSHESLDQVGEEKEAMNTRESGKASSSLGLQDFDLLRVIGRGSYAKVLLVRLKKTDRIYAMKVVKKELVNDDEDIDWVQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALNYLHERGIIYRDLKLDNVLLDSEGHIKLTDYGMCKEGLRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEKQIRIPRSLSVKAASVLKSFLNKDPKERLGCHPQTGFADIQGHPFFRNVDWDMMEQKQVVPPFKPNISGEFGLDNFDSQFTNEPVQLTPDDDDIVRKIDQSEFEGFEYINPLLMSAEECV", "length": 596, "reference_go_mf": ["GO:0005524", "GO:0004699", "GO:0005543", "GO:0004672", "GO:0106310", "GO:0004674"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_c49843bfec097a5cbd5d"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_757_1stc_assembly1", "enzyme_name": "cAMP-dependent protein kinase", "ec": ["2.7.11.11"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00517", "alignment_score": 656.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [15, 351], "sequence": "MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWENPAQNTAHLDQFERIKTLGTGSFGRVMLVKHMETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF", "length": 351, "reference_go_mf": ["GO:0005524", "GO:0004691", "GO:0140198", "GO:0000287", "GO:0030145", "GO:0019904", "GO:0034237", "GO:0004672", "GO:0019901", "GO:0106310", "GO:0004674", "GO:0004712"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_8bdfff4876e2a382fc5d"}, "alternative_alignments": [{"accession": "P61926", "alignment_score": 6.0, "observed_coverage": 0.008982035928143712, "aligned_identity": 1.0, "canonical_span": [33, 36], "length": 76, "reference_go_mf": ["GO:0004862", "GO:0060090", "GO:0140678", "GO:0034236"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_758_1u5u_assembly1", "enzyme_name": "hydroperoxide dehydratase", "ec": ["4.2.1.92"], "controls": [{"chain": "A", "status": "reference_overlength", "selected": {"accession": "O16025", "alignment_score": 732.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [2, 368], "sequence": "MTWKNFGFEIFGEKYGQEELEKRIKDEHTPPPDSPVFGGLKLKLKKEKFKTLFTLGTTLKGFRRATHTVGTGGIGEITIVNDPKFPEHEFFTAGRTFPARLRHANLKYPDDAGADARSFSIKFADSDSDGPLDIVMNTGEANIFWNSPSLEDFVPVEEGDAAEEYVYKNPYYYYNLVEALRRAPDTFAHLYYYSQVTMPFKAKDGKVRYCRYRALPGDVDIKEEDESGRLTEEEQRKIWIFSRHENEKRPDDYLRKEYVERLQKGPVNYRLQIQIHEASPDDTATIFHAGILWDKETHPWFDLAKVSIKTPLSPDVLEKTAFNIANQPASLGLLEAKSPEDYNSIGELRVAVYTWVQHLRKLKIGSLVPAGQNAIYNVEVETGDREHAGTDATITIRITGAKGRTDYLKLDKWFHNDFEAGSKEQYTVQGFDVGDIQLIELHSDGGGYWSGDPDWFVNRVIIISSTQDRVYSFPCFRWVIKDMVLFPGEATLPFNEVPAIVSEQRQKELEQRKLTYQWDYVSDDMPGNIKAKTHDDLPRDVQFTDEKSRSYQESRKAALVNLGIGSLFTMFENWDSYDDYHILYRNWILGGTPNMADRWHEDRWFGYQFLNGANPVILTRCDALPSNFPVTNEHVNASLDRGKNLDEEIKDGHIYIVDFKVLVGAKSYGGPVLEDIGYKVPDHLKHDEADIRYCAAPLALFYVNKLGHLMPIAIQINQEPGPENPIWTPHEENEHDWMMAKFWLGVAESNFHQLNTHLLRTHLTTESFALSTWRNLASAHPVFKLLQPHIYGVLAIDTIGRKELIGSGGIVDQSLSLGGGGHVTFMEKCFKEVNLQDYHLPNALKKRGVDDPSKLPGFYYRDDGLALWEAIETFIGEIIAIFYKNDDDVKRDNEIQSWIYDVHKNGWRVNPGHQDHGVPASFESREQLKEVLTSLVFTFSCQHAAVNFSQKDHYGFTPNAPAVLRHPPPKKKGEATLQSILSTLPSKSQAAKAIATVYILTKFSEDERYLGNYSATAWEDKDALDAINRFQDKLEDISKKIKQRNENLEVPYIYLLPERIPNGTAI", "length": 1066, "reference_go_mf": ["GO:0047677", "GO:0020037", "GO:0005506"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_75_12as_assembly1", "enzyme_name": "aspartate-ammonia ligase", "ec": ["6.3.1.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00963", "alignment_score": 648.0, "observed_coverage": 1.0, "aligned_identity": 0.9938837920489296, "canonical_span": [3, 330], "sequence": "MKTAYIAKQRQISFVKSHFSRQLEERLGLIEVQAPILSRVGDGTQDNLSGCEKAVQVKVKALPDAQFEVVHSLAKWKRQTLGQHDFSAGEGLYTHMKALRPDEDRLSPLHSVYVDQWDWERVMGDGERQFSTLKSTVEAIWAGIKATEAAVSEEFGLAPFLPDQIHFVHSQELLSRYPDLDAKGRERAIAKDLGAVFLVGIGGKLSDGHRHDVRAPDYDDWSTPSELGHAGLNGDILVWNPVLEDAFELSSMGIRVDADTLKHQLALTGDEDRLELEWHQALLRGEMPQTIGGGIGQSRLTMLLLQLPHIGQVQCGVWPAAVRESVPSLL", "length": 330, "reference_go_mf": ["GO:0004071", "GO:0005524", "GO:0042802", "GO:0042803"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_ced8143210734e957a99"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_760_1l0o_assembly1", "enzyme_name": "non-specific serine/threonine protein kinase", "ec": ["2.7.11.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "O32727", "alignment_score": 269.0, "observed_coverage": 0.9645390070921985, "aligned_identity": 0.9926470588235294, "canonical_span": [0, 136], "sequence": "MRNEMHLQFSARSENESFARVTVAAFVAQLDPTTDELTEIKTVVSEAVTNAIIHGYNNDPNGIVSISVIIEDGVVHLTVRDEGVGIPDIEEARQPLFTTKPELERSGMGFTIMENFMDEVIVESEVNKGTTVYLKKAYCEKQTLCN", "length": 146, "reference_go_mf": ["GO:0005524", "GO:0106310", "GO:0004674", "GO:0016989"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_9f96d664bc5e8da5aa64"}, "alternative_alignments": [{"accession": "O32728", "alignment_score": 7.0, "observed_coverage": 0.03546099290780142, "aligned_identity": 0.8, "canonical_span": [193, 198], "length": 250, "reference_go_mf": ["GO:0003677", "GO:0016987"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_761_1iu4_assembly1", "enzyme_name": "protein-glutamine gamma-glutamyltransferase (bacterial)", "ec": ["2.3.2.13"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P81453", "alignment_score": 662.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [76, 407], "sequence": "MRIRRRALVFATMSAVLCTAGFMPSAGEAAADNGAGEETKSYAETYRLTADDVANINALNESAPAASSAGPSFRAPDSDDRVTPPAEPLDRMPDPYRPSYGRAETVVNNYIRKWQQVYSHRDGRKQQMTEEQREWLSYGCVGVTWVNSGQYPTNRLAFASFDEDRFKNELKNGRPRSGETRAEFEGRVAKESFDEEKGFQRAREVASVMNRALENAHDESAYLDNLKKELANGNDALRNEDARSPFYSALRNTPSFKERNGGNHDPSRMKAVIYSKHFWSGQDRSSSADKRKYGDPDAFRPAPGTGLVDMSRDRNIPRSPTSPGEGFVNFDYGWFGAQTEADADKTVWTHGNHYHAPNGSLGAMHVYESKFRNWSEGYSDFDRGAYVITFIPKSWNTAPDKVKQGWP", "length": 407, "reference_go_mf": ["GO:0003810"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_7145c24c488a08ffd75b"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_762_1fc4_assembly1", "enzyme_name": "glycine C-acetyltransferase", "ec": ["2.3.1.29"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0AB77", "alignment_score": 706.0, "observed_coverage": 0.9922879177377892, "aligned_identity": 1.0, "canonical_span": [1, 398], "sequence": "MRGEFYQQLTNDLETARAEGLFKEERIITSAQQADITVADGSHVINFCANNYLGLANHPDLIAAAKAGMDSHGFGMASVRFICGTQDSHKELEQKLAAFLGMEDAILYSSCFDANGGLFETLLGAEDAIISDALNHASIIDGVRLCKAKRYRYANNDMQELEARLKEAREAGARHVLIATDGVFSMDGVIANLKGVCDLADKYDALVMVDDSHAVGFVGENGRGSHEYCDVMGRVDIITGTLGKALGGASGGYTAARKEVVEWLRQRSRPYLFSNSLAPAIVAASIKVLEMVEAGSELRDRLWANARQFREQMSAAGFTLAGADHAIIPVMLGDAVVAQKFARELQKEGIYVTGFFYPVVPKGQARIRTQMSAAHTPEQITRAVEAFTRIGKQLGVIA", "length": 398, "reference_go_mf": ["GO:0008890", "GO:0016874", "GO:0046872", "GO:0030170"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_07c10c5196973575a0b0"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_763_2bhg_assembly1", "enzyme_name": "picornain 3C", "ec": ["3.4.22.28"], "controls": [{"chain": "A", "status": "reference_overlength", "selected": {"accession": "P03306", "alignment_score": 299.0, "observed_coverage": 0.967391304347826, "aligned_identity": 0.9775280898876404, "canonical_span": [1655, 1846], "sequence": "MNTTNCFIALVYLIREIKTLFRSRTKGKMEFTLHNGEKKTFYSRPNNHDNCWLNTILQLFRYVDEPFFDWVYNSPENLTLDAIKQLENFTGLELHEGGPPALVIWNIKHLLQTGIGTASRPSEVCMVDGTDMCLADFHAGIFMKGQEHAVFACVTSDGWYAIDDEDFYPWTPDPSDVLVFVPYDQEPLNGDWKTQVQKKLKGAGQSSPATGSQNQSGNTGSIINNYYMQQYQNSMSTQLGDNTISGGSNEGSTDTTSTHTTNTQNNDWFSKLASSAFTGLFGALLADKKTEETTLLEDRILTTRNGHTTSTTQSSVGVTYGYSTEEDHVAGPNTSGLETRVVQAERFFKKFLFDWTTDKPFGYLTKLELPTDHHGVFGHLVDSYAYMRNGWDVEVSAVGNQFNGGCLLVAMVPEWKAFDTREKYQLTLFPHQFISPRTNMTAHITVPYLGVNRYDQYKKHKPWTLVVMVLSPLTVSNTAAPQIKVYANIAPTYVHVAGELPSKEGIFPVACADGYGGLVTTDPKTADPVYGKVYNPPKTNYPGRFTNLLDVAEACPTFLRFDDGKPYVVTRADDTRLLAKFDVSLAAKHMSNTYLSGIAQYYTQYSGTINLHFMFTGSTDSKARYMVAYIPPGVETPPDTPEEAAHCIHAEWDTGLNSKFTFSIPYVSAADYAYTASDTAETTNVQGWVCVYQITHGKAENDTLLVSASAGKDFELRLPIDPRTQTTTTGESADPVTTTVENYGGDTQVQRRHHTDVGFIMDRFVKINSLSPTHVIDLMQTHKHGIVGALLRAATYYFSDLEIVVRHDGNLTWVPNGAPEAALSNTSNPTAYNKAPFTRLALPYTAPHRVLATVYDGTNKYSASDSRSGDLGSIAARVATQLPASFNYGAIQAQAIHELLVRMKRAELYCPRPLLAIKVTSQDRYKQKIIAPAKQLLNFDLLKLAGDVESNLGPFFFADVRSNFSKLVDTINQMQEDMSTKHGPDFNRLVSAFEELATGVKAIRTGLDEAKPWYKLIKLLSRLSCMAAVAARSKDPVLVAIMLADTGLEILDSTFVVKKSSDSLSSLFHVPAPAFSFGAPVLLAGLVKVASSFFRSTPEDLERAEKQLKARDINDIFAILKNGEWLVKLILAIRDWIKAWIASEEKFVTMTDLVPGILEKQRDLNDPGKYKEAKEWLDNARQACLKSGNVHIANLCKVVAPAPSKSRPEPVVVCLRGKSGQGKSFLANVLAQAISTHFTGRIDSVWYCPPDPDHFDGYNQQTVVVMDDLGQNPDGKDFKYFAQMVSTTGFIPPMASLEDKGKPFNSKVIIATTNLYSGFTPRTMVCPDALNRRFHFDIDVSAKDGYKINNKLDIIKALEDTHTNPVAMFQYDCALLNGMAVEMKRLQQDMFKPQPPLQNVYQLVQEVIERVELHEKVSSHPIFKQISIPSQKSVLYFLIEKGQHEAAIEFFEGMVHDSVKEELRPLIQQTSFVKRAFKRLKENFEIVALCLTLLANIVIMIRETRKRQKMVDDAVNEYIERANITTDDKTLDEAEKNPLETSGASTVGFRERSLTGQKVRDDVSSEPAQPAEDQPQAEGPYSGPLERQKPLKVRAKLPQQEGPYAGPMERQKPLKVKVKAPVVKEGPYEGPVKKPVALKVKARNLIVTESGAPPTDLQKMVMGNTKPVELNLDGKTVAICCATGVFGTAYLVPRHLFAEKYDKIMLDGRAMTDSDYRVFEFEIKVKGQDMLSDAALIVLHRGNCVRDITKHFRDTARMKKGTPVVGVVNNADVGRLIFSGEALTYKDIVVCMDGDTMPGLFAYKAATRAGYCGGAVLAKDGADTFIVGTHSAGGNGVGYCSCVSRSMLQKMKAHVDPEPHHEGLIVDTRDVEERVHVMRKTKLAPTVAYGVFNPEFGPAALSNKDPRLNEGVVLDDVIFSKHKGDAKMTEEDKALFRRCAADYASRLHSVLGTANAPLSIYEAIKGVDGLDAMEPDTAPGLPWALQGKRRGALIDFENGTVGPEVEAALKLMEKREYKFACQTFLKDEIRPMEKVRAGKTRIVDVLPVEHILYTKMMIGRFCAQMHSNNGPQIGSAVGCNPDVDWQRFGTHFAQYRNVWDVDYSAFDANHCSDAMNIMFEEVFRTDFGFHPNAEWILKTLVNTEHAYENKRITVEGGMPSGCSATSIINTILNNIYVLYALRRHYEGVELDTYTMISYGDDIVVASDYDLDFEALKPHFKSLGQTITPADKSDKGFVLGQSITDVTFLKRHFHMDYGTGFYKPVMASKTLEAILSFARRGTIQEKLISVAGLAVHSGPDEYRRLFEPFQGLFEIPSYRSLYLRWVNAVCGDA", "length": 2332, "reference_go_mf": ["GO:0005524", "GO:0015267", "GO:0004197", "GO:0017111", "GO:0003723", "GO:0003724", "GO:0003968", "GO:0005198"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_767_1r30_assembly1", "enzyme_name": "biotin synthase", "ec": ["2.8.1.6"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P12996", "alignment_score": 624.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [3, 315], "sequence": "MAHRPRWTLSQVTELFEKPLLDLLFEAQQVHRQHFDPRQVQVSTLLSIKTGACPEDCKYCPQSSRYKTGLEAERLMEVEQVLESARKAKAAGSTRFCMGAAWKNPHERDMPYLEQMVQGVKAMGLEACMTLGTLSESQAQRLANAGLDYYNHNLDTSPEFYGNIITTRTYQERLDTLEKVRDAGIKVCSGGIVGLGETVKDRAGLLLQLANLPTPPESVPINMLVKVKGTPLADNDDVDAFDFIRTIAVARIMMPTSYVRLSAGREQMNEQTQAMCFMAGANSIFYGCKLLTTPNPEEDKDLQLFRKLGLNPQQTAVLAGDNEQQQRLEQALMTPDTDEYYNAAAL", "length": 346, "reference_go_mf": ["GO:0051537", "GO:0051539", "GO:0004076", "GO:0005506", "GO:0042803"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_21045ab8ac9ddb65a114"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_768_1qv0_assembly1", "enzyme_name": "Renilla-luciferin 2-monooxygenase", "ec": ["1.13.12.5"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q27709", "alignment_score": 359.5, "observed_coverage": 1.0, "aligned_identity": 0.9945945945945946, "canonical_span": [6, 195], "sequence": "MSSKYAVKLKTDFDNPRWIKRHKHMFDFLDINGNGKITLDEIVSKASDDICAKLEATPEQTKRHQVCVEAFFRGCGMEYGKEIAFPQFLDGWKQLATSELKKWARNEPTLIREWGDAVFDIFDKDGSGTITLDEWKAYGKISGISPSQEDCEATFRHCDLDNSGDLDVDEMTRQHLGFWYTLDPEADGLYGNGVP", "length": 195, "reference_go_mf": ["GO:0005509"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_0afab62a8ed1c6659eca"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_76_1a26_assembly1", "enzyme_name": "NAD+ ADP-ribosyltransferase", "ec": ["2.4.2.30"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P26446", "alignment_score": 702.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [658, 1009], "sequence": "MAETGDKPYRAEYAKSGRASCKKCGESIAKDSLRLALMVQSPMFDGKVPHWHHYSCFWKRARIVSHTDIDGFPELRWEDQEKIKKAIETGALQEEKGGTRKEVGKAEKSLTDFAAEYAKSNRSTCKGCEQKIEKGQIRISKKMVHPEKPQLGMIDNWYHPDCFVSRRAELGFLPAYGATQLLGFSILKAEDKETLKKQLPATKTEGKRKGEEVDGNVVAKKKSRKEKEKESKQEKQLKEQTELIWGIKDELRKVCSTNDLKELLIANKQEVPSGENAILDRVADGMAFGALLPCEECKGQFVFKSDAYYCSGDITAWTKCVAKTQTPNRKDWVIPKEFREIPYLKKFKCKKQDRIFPPEAATVNSAPPPPASAPLTETVTAPQDKPLTNMKILTLGKLSKNKEEVKNIVEELGGKMTTTANKATLCISTQKEVEKMSKKMEEVKDAKVRVVSEEFLKDVKSSNKGFQELLSLHAISPWGAEVKTEHQEVAVDGKCSKPANMKSAGKVKEEQGPSKSEKKMKLTVKGGAAVDPDSGLEDSAHVFEKGGKIFSATLGLVDIVKGTNSYYKLQLLEDDRESRYWVFRSWGRVGTVIGSNKLEQMPSKEDAVEHFLNLYEEKTGNSWHSKNFTKYPKKFYPLEIDYGQDEEAVRKLTVSAGTKSKLAKPIQDLIKMIFDVESMKKAMVEFEIDLQKMPLGKLSKRQIQSAYSILNEVQQAVSDGGSESQILDLSNRFYTLIPHDFGMKKPPLLSNLEYIQAKVQMLDNLLDIEVAYSLLRGGNEDGDKDPIDINYEKLRTDIKVVDKDSEEAKIIKQYVKNTHAATHNAYDLKVVEIFRIEREGESQRYKPFKQLHNRQLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQADPIGLILLGEVALGNMYELKNASHITKLPKGKHSVKGLGKTAPDPTATTTLDGVEVPLGNGISTGINDTCLLYNEYIVYDVAQVNLKYLLKLKFNYKTSLW", "length": 1011, "reference_go_mf": ["GO:0003684", "GO:0051287", "GO:0003950", "GO:1990404", "GO:0140806", "GO:0140807", "GO:0140815", "GO:0140805", "GO:0140808", "GO:0031491", "GO:0042803", "GO:1990165", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_88da2e1b21cebd218353"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_771_1uk7_assembly1", "enzyme_name": "2-hydroxymuconate-semialdehyde hydrolase", "ec": ["3.7.1.9"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P96965", "alignment_score": 539.0, "observed_coverage": 1.0, "aligned_identity": 0.996309963099631, "canonical_span": [2, 273], "sequence": "MANLEIGKSILAAGVLTNYHDVGEGQPVILIHGSGPGVSAYANWRLTIPALSKFYRVIAPDMVGFGFTDRPENYNYSKDSWVDHIIGIMDALEIEKAHIVGNSFGGGLAIATALRYSERVDRMVLMGAAGTRFDVTEGLNAVWGYTPSIENMRNLLDIFAYDRSLVTDELARLRYEASIQPGFQESFSSMFPEPRQRWIDALASSDEDIKTLPNETLIIHGREDQVVPLSSSLRLGELIDRAQLHVFGRCGHWTQIEQTDRFNRLVVEFFNEANTPKLVGRP", "length": 282, "reference_go_mf": ["GO:0003824"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_af8b756d4d41e3ff490e"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_774_1oba_assembly1", "enzyme_name": "lysozyme (glycosyl hydrolase 25 family)", "ec": ["3.2.1.17"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P15057", "alignment_score": 673.0, "observed_coverage": 1.0, "aligned_identity": 0.9970414201183432, "canonical_span": [1, 339], "sequence": "MVKKNDLFVDVSSHNGYDITGILEQMGTTNTIIKISESTTYLNPCLSAQVEQSNPIGFYHFARFGGDVAEAEREAQFFLDNVPMQVKYLVLDYEDDPSGDAQANTNACLRFMQMIADAGYKPIYYSYKPFTHDNVDYQQILAQFPNSLWIAGYGLNDGTANFEYFPSMDGIRWWQYSSNPFDKNIVLLDDEEDDKPKTAGTWKQDSKGWWFRRNNGSFPYNKWEKIGGVWYYFDSKGYCLTSEWLKDNEKWYYLKDNGAMATGWVLVGSEWYYMDDSGAMVTGWVKYKNNWYYMTNERGNMVSNEFIKSGKGWYFMNTNGELADNPSFTKEPDGLITVA", "length": 339, "reference_go_mf": ["GO:0003796"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_e882ff91ac6f60f6e5af"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_776_1rgq_assembly1", "enzyme_name": "hepacivirin", "ec": ["3.4.21.98"], "controls": [{"chain": "A", "status": "reference_overlength", "selected": {"accession": "P27958", "alignment_score": 299.0, "observed_coverage": 1.0, "aligned_identity": 0.9805194805194806, "canonical_span": [1053, 1207], "sequence": "MSTNPKPQRKTKRNTNRRPQDVKFPGGGQIVGGVYLLPRRGPRLGVRATRKTSERSQPRGRRQPIPKARRPEGRTWAQPGYPWPLYGNEGCGWAGWLLSPRGSRPSWGPTDPRRRSRNLGKVIDTLTCGFADLMGYIPLVGAPLGGAARALAHGVRVLEDGVNYATGNLPGCSFSIFLLALLSCLTVPASAYQVRNSSGLYHVTNDCPNSSVVYEAADAILHTPGCVPCVREGNASRCWVAVTPTVATRDGKLPTTQLRRHIDLLVGSATLCSALYVGDLCGSVFLVGQLFTFSPRHHWTTQDCNCSIYPGHITGHRMAWNMMMNWSPTAALVVAQLLRIPQAIMDMIAGAHWGVLAGIKYFSMVGNWAKVLVVLLLFAGVDAETHVTGGNAGRTTAGLVGLLTPGAKQNIQLINTNGSWHINSTALNCNESLNTGWLAGLFYQHKFNSSGCPERLASCRRLTDFAQGWGPISYANGSGLDERPYCWHYPPRPCGIVPAKSVCGPVYCFTPSPVVVGTTDRSGAPTYSWGANDTDVFVLNNTRPPLGNWFGCTWMNSTGFTKVCGAPPCVIGGVGNNTLLCPTDCFRKYPEATYSRCGSGPRITPRCMVDYPYRLWHYPCTINYTIFKVRMYVGGVEHRLEAACNWTRGERCDLEDRDRSELSPLLLSTTQWQVLPCSFTTLPALSTGLIHLHQNIVDVQYLYGVGSSIASWAIKWEYVVLLFLLLADARVCSCLWMMLLISQAEAALENLVILNAASLAGTHGLVSFLVFFCFAWYLKGRWVPGAVYALYGMWPLLLLLLALPQRAYALDTEVAASCGGVVLVGLMALTLSPYYKRYISWCMWWLQYFLTRVEAQLHVWVPPLNVRGGRDAVILLTCVVHPALVFDITKLLLAIFGPLWILQASLLKVPYFVRVQGLLRICALARKIAGGHYVQMAIIKLGALTGTCVYNHLAPLRDWAHNGLRDLAVAVEPVVFSRMETKLITWGADTAACGDIINGLPVSARRGQEILLGPADGMVSKGWRLLAPITAYAQQTRGLLGCIITSLTGRDKNQVEGEVQIVSTATQTFLATCINGVCWTVYHGAGTRTIASPKGPVIQTYTNVDQDLVGWPAPQGSRSLTPCTCGSSDLYLVTRHADVIPVRRRGDSRGSLLSPRPISYLKGSSGGPLLCPTGHAVGLFRAAVCTRGVAKAVDFIPVENLETTMRSPVFTDNSSPPAVPQSFQVAHLHAPTGSGKSTKVPAAYAAKGYKVLVLNPSVAATLGFGAYMSKAHGVDPNIRTGVRTITTGSPITYSTYGKFLADAGCSGGAYDIIICDECHSTDATSISGIGTVLDQAETAGARLVVLATATPPGSVTVSHPNIEEVALSTTGEIPFYGKAIPLEVIKGGRHLIFCHSKKKCDELAAKLVALGINAVAYYRGLDVSVIPTSGDVVVVSTDALMTGFTGDFDSVIDCNTCVTQTVDFSLDPTFTIETTTLPQDAVSRTQRRGRTGRGKPGIYRFVAPGERPSGMFDSSVLCECYDAGCAWYELTPAETTVRLRAYMNTPGLPVCQDHLGFWEGVFTGLTHIDAHFLSQTKQSGENFPYLVAYQATVCARAQAPPPSWDQMRKCLIRLKPTLHGPTPLLYRLGAVQNEVTLTHPITKYIMTCMSADLEVVTSTWVLVGGVLAALAAYCLSTGCVVIVGRIVLSGKPAIIPDREVLYQEFDEMEECSQHLPYIEQGMMLAEQFKQKALGLLQTASRHAEVITPAVQTNWQKLEVFWAKHMWNFISGIQYLAGLSTLPGNPAIASLMAFTAAVTSPLTTGQTLLFNILGGWVAAQLAAPGAATAFVGAGLAGAALDSVGLGKVLVDILAGYGAGVAGALVAFKIMSGEVPSTEDLVNLLPAILSPGALAVGVVFASILRRRVGPGEGAVQWMNRLIAFASRGNHVSPTHYVPESDAAARVTAILSSLTVTQLLRRLHQWISSECTTPCSGSWLRDIWDWICEVLSDFKTWLKAKLMPQLPGIPFVSCQRGYRGVWRGDGIMHTRCHCGAEITGHVKNGTMRIVGPRTCKNMWSGTFFINAYTTGPCTPLPAPNYKFALWRVSAEEYVEIRRVGDFHYVSGMTTDNLKCPCQIPSPEFFTELDGVRLHRFAPPCKPLLREEVSFRVGLHEYPVGSQLPCEPEPDVAVLTSMLTDPSHITAEAAGRRLARGSPPSMASSSASQLSAPSLKATCTANHDSPDAELIEANLLWRQEMGGNITRVESENKVVILDSFDPLVAEEDEREVSVPAEILRKSRRFAPALPVWARPDYNPLLVETWKKPDYEPPVVHGCPLPPPRSPPVPPPRKKRTVVLTESTLPTALAELATKSFGSSSTSGITGDNTTTSSEPAPSGCPPDSDVESYSSMPPLEGEPGDPDLSDGSWSTVSSGADTEDVVCCSMSYSWTGALVTPCAAEEQKLPINALSNSLLRHHNLVYSTTSRSACQRKKKVTFDRLQVLDSHYQDVLKEVKAAASKVKANLLSVEEACSLAPPHSAKSKFGYGAKDVRCHARKAVAHINSVWKDLLEDSVTPIDTTIMAKNEVFCVQPEKGGRKPARLIVFPDLGVRVCEKMALYDVVSKLPLAVMGSSYGFQYSPGQRVEFLVQAWKSKKTPMGLSYDTRCFDSTVTESDIRTEEAIYQCCDLDPQARVAIKSLTERLYVGGPLTNSRGENCGYRRCRASRVLTTSCGNTLTRYIKARAACRAAGLQDCTMLVCGDDLVVICESAGVQEDAASLRAFTEAMTRYSAPPGDPPQPEYDLELITSCSSNVSVAHDGAGKRVYYLTRDPTTPLARAAWETARHTPVNSWLGNIIMFAPTLWARMILMTHFFSVLIARDQLEQALNCEIYGACYSIEPLDLPPIIQRLHGLSAFSLHSYSPGEINRVAACLRKLGVPPLRAWRHRAWSVRARLLARGGKAAICGKYLFNWAVRTKLKLTPITAAGRLDLSGWFTAGYSGGDIYHSVSHARPRWFWFCLLLLAAGVGIYLLPNR", "length": 3011, "reference_go_mf": ["GO:0034062", "GO:0005524", "GO:0016887", "GO:0015267", "GO:0004197", "GO:0019900", "GO:0017111", "GO:0003723", "GO:0003724", "GO:0003968", "GO:0004252", "GO:0017124", "GO:0005198", "GO:0035663", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": [{"accession": "O39914", "alignment_score": 6.0, "observed_coverage": 0.03896103896103896, "aligned_identity": 0.6666666666666666, "canonical_span": [5, 11], "length": 88, "reference_go_mf": [], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_777_1aam_assembly1", "enzyme_name": "aspartate transaminase", "ec": ["2.6.1.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00509", "alignment_score": 789.0, "observed_coverage": 1.0, "aligned_identity": 0.9974747474747475, "canonical_span": [0, 396], "sequence": "MFENITAAPADPILGLADLFRADERPGKINLGIGVYKDETGKTPVLTSVKKAEQYLLENETTKNYLGIDGIPEFGRCTQELLFGKGSALINDKRARTAQTPGGTGALRVAADFLAKNTSVKRVWVSNPSWPNHKSVFNSAGLEVREYAYYDAENHTLDFDALINSLNEAQAGDVVLFHGCCHNPTGIDPTLEQWQTLAQLSVEKGWLPLFDFAYQGFARGLEEDAEGLRAFAAMHKELIVASSYSKNFGLYNERVGACTLVAADSETVDRAFSQMKAAIRANYSNPPAHGASVVATILSNDALRAIWEQELTDMRQRIQRMRQLFVNTLQEKGANRDFSFIIKQNGMFSFSGLTKEQVLRLREEFGVYAVASGRVNVAGMTPDNMAPLCEAIVAVL", "length": 396, "reference_go_mf": ["GO:0042802", "GO:0004069", "GO:0004838", "GO:0042803", "GO:0030170"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_ce1f3d587de57cc79eaf"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_779_1goj_assembly1", "enzyme_name": "plus-end-directed kinesin ATPase", "ec": ["5.6.1.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P48467", "alignment_score": 708.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 355], "sequence": "MSSSANSIKVVARFRPQNRVEIESGGQPIVTFQGPDTCTVDSKEAQGSFTFDRVFDMSCKQSDIFDFSIKPTVDDILNGYNGTVFAYGQTGAGKSYTMMGTSIDDPDGRGVIPRIVEQIFTSILSSAANIEYTVRVSYMEIYMERIRDLLAPQNDNLPVHEEKNRGVYVKGLLEIYVSSVQEVYEVMRRGGNARAVAATNMNQESSRSHSIFVITITQKNVETGSAKSGQLFLVDLAGSEKVGKTGASGQTLEEAKKINKSLSALGMVINALTDGKSSHVPYRDSKLTRILQESLGGNSRTTLIINCSPSSYNDAETLSTLRFGMRAKSIKNKAKVNAELSPAELKQMLAKAKTQITSFENYIVNLESEVQVWRGGETVPKEKWVPPLELAITPSKSASTTARPSTPSRLLPESRAETPAISDRAGTPSLPLDKDEREEFLRRENELQDQIAEKESIAAAAERQLRETKEELIALKDHDSKLGKENERLISESNEFKMQLERLAFENKEAQITIDGLKDANSELTAELDEVKQQMLDMKMSAKETSAVLDEKEKKKAEKMAKMMAGFDLSGDVFSDNERAVADAIAQLDALFEISSAGDAIPPEDIKALREKLVETQGFVRQAELSSFSAASSDAEARKRAELEARLEALQQEHEELLSRNLTEADKEEVKALLAKSLSDKSAVQVELVEQLKADIALKNSETEHLKALVDDLQRRVKAGGAGVAMANGKTVQQQLAEFDVMKKSLMRDLQNRCERVVELEISLDETREQYNNVLRSSNNRAQQKKMAFLERNLEQLTQVQRQLVEQNSALKKEVAIAERKLMARNERIQSLESLLQESQEKMAQANHKFEVQLAAVKDRLEAAKAGSTRGLGTDAGLGGFSIGSRIAKPLRGGGDAVAGATATNPTIATLQQNPPENKRSSWFFQKS", "length": 928, "reference_go_mf": ["GO:0005524", "GO:0099609", "GO:0008574"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_0459c74d9b5209462ece"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_77_1afw_assembly1", "enzyme_name": "acetyl-CoA C-acyltransferase", "ec": ["2.3.1.16"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P27796", "alignment_score": 773.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [24, 417], "sequence": "MSQRLQSIKDHLVESAMGKGESKRKNSLLEKRPEDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNVLNVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVESMTNNYKNVNPLGMISSEELQKNREAKKCLIPMGITNENVAANFKISRKDQDEFAANSYQKAYKAKNEGLFEDEILPIKLPDGSICQSDEGPRPNVTAESLSSIRPAFIKDRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGPAYAIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCTGARQVATILRELKKDQIGVVSMCIGTGMGAAAIFIKE", "length": 417, "reference_go_mf": ["GO:0003988", "GO:0003729"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_c5acd0df6ad2275cdd04"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_780_1hqc_assembly1", "enzyme_name": "DNA helicase", "ec": ["3.6.4.12"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q5SL87", "alignment_score": 625.0, "observed_coverage": 1.0, "aligned_identity": 0.9968152866242038, "canonical_span": [4, 318], "sequence": "MEDLALRPKTLDEYIGQERLKQKLRVYLEAAKARKEPLEHLLLFGPPGLGKTTLAHVIAHELGVNLRVTSGPAIEKPGDLAAILANSLEEGDILFIDEIHRLSRQAEEHLYPAMEDFVMDIVIGQGPAARTIRLELPRFTLIGATTRPGLITAPLLSRFGIVEHLEYYTPEELAQGVMRDARLLGVRITEEAALEIGRRSRGTMRVAKRLFRRVRDFAQVAGEEVITRERALEALAALGLDELGLEKRDREILEVLILRFGGGPVGLATLATALSEDPGTLEEVHEPYLIRQGLLKRTPRGRVATELAYRHLGYPPPVGPLLEP", "length": 324, "reference_go_mf": ["GO:0005524", "GO:0016887", "GO:0000400", "GO:0009378"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_58633bfe17700d6a2373"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_781_1p4n_assembly1", "enzyme_name": "UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase", "ec": ["2.3.2.10"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q9EY50", "alignment_score": 670.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 336], "sequence": "MPVLNLNDPQAVERYEEFMRQSPYGQVTQDLGWAKVKNNWEPVDVYLEDDQGAIIAAMSMLLGDTPTDKKFAYASKGPVMDVTDVDLLDRLVDEAVKALDGRAYVLRFDPEVAYSDEFNTTLQDHGYVTRNRNVADAGMHATIQPRLNMVLDLTKFPDAKTTLDLYPSKTKSKIKRPFRDGVEVHSGNSATELDEFFKTYTTMAERHGITHRPIEYFQRMQAAFDADTMRIFVAEREGKLLSTGIALKYGRKIWYMYAGSMDGNTYYAPYAVQSEMIQWALDTNTDLYDLGGIESESTDDSLYVFKHVFVKDAPREYIGEIDKVLDPEVYAELVKD", "length": 336, "reference_go_mf": ["GO:0047206"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_10f244798c0375c104c2"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_782_1ei5_assembly1", "enzyme_name": "D-stereospecific aminopeptidase (peptidase S12 family)", "ec": ["3.4.11.19"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q9ZBA9", "alignment_score": 1036.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [2, 520], "sequence": "MSKFDTSALEAFVRHIPQNYKGPGGVVAVVKDGEVVLQHAWGFADLRTRTPMTLDTRMPICSVSKQFTCAVLLDAVGEPELLDDALEAYLDKFEDERPAVRDLCNNQSGLRDYWALSVLCGADPEGVFLPAQAQSLLRRLKTTHFEPGSHYSYCNGNFRILADLIEAHTGRTLVDILSERIFAPAGMKRAELISDTALFDECTGYEGDTVRGFLPATNRIQWMGDAGICASLNDMIAWEQFIDATRDDESGLYRRLSGPQTFKDGVAAPYGFGLNLHETGGKRLTGHGGALRGWRCQRWHCADERLSTIAMFNFEGGASEVAFKLMNIALGVSSSEVSRVEADSAWFGSWLDDETGLVLSLEDAGHGRMKARFGTSPEMMDVVSANEARSAVTTIRRDGETIELVRASENLRLSMKRVKGEAKHDIIGRYHSDELDADLLLVSEGGAIYGAFEGFLGKSDMYPLYSVGSDVWLLPVQRSMDAPSPGEWKLVFRRDDKGEITGLSVGCWLARGVEYRRVQP", "length": 520, "reference_go_mf": ["GO:0004177"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_f9b363a235cbf81d687b"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_784_1w0h_assembly1", "enzyme_name": "3'-5' exoribonuclease 1", "ec": ["3.1.-.-"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q8IV48", "alignment_score": 358.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [122, 321], "sequence": "MEDPQSKEPAGEAVALALLESPRPEGGEEPPRPSPEETQQCKFDGQETKGSKFITSSASDFSDPVYKEIAITNGCINRMSKEELRAKLSEFKLETRGVKDVLKKRLKNYYKKQKLMLKESNFADSYYDYICIIDFEATCEEGNPPEFVHEIIEFPVVLLNTHTLEIEDTFQQYVRPEINTQLSDFCISLTGITQDQVDRADTFPQVLKKVIDWMKLKELGTKYKYSLLTDGSWDMSKFLNIQCQLSRLKYPPFAKKWINIRKSYGNFYKVPRSQTKLTIMLEKLGMDYDGRPHCGLDDSKNIARIAVRMLQDGCELRINEKMHAGQLMSVSSSLPIEGTPPPQMPHFRK", "length": 349, "reference_go_mf": ["GO:0008408", "GO:0000175", "GO:0008859", "GO:0071207", "GO:0043022", "GO:0019843"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_0391923d22a775f926bf"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_786_1ge7_assembly1", "enzyme_name": "peptidyl-Lys metalloendopeptidase", "ec": ["3.4.24.20"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P81054", "alignment_score": 334.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [181, 348], "sequence": "MFSSVMVALVSLAVAVSANPGLSLKVSGPEAVDGVNNLKVVTTITNTGDETLKLLNDPRGALHTMPTDTFAITNESGETPSFIGVKVKYVPSMAAKSTGENVFAVIAPGQSVNVEHDLSAAYNFTSSGAGTYALEALNVFNYIDPETNEPVEIWADAEAHTTAVSGKLAVVRATPTLTRPVTYNGCSSSEQSALAAAASAAQSYVAESLSYLQTHTAATPRYTTWFGSYISSRHSTVLQHYTDMNSNDFSSYSFDCTCTAAGTFAYVYPNRFGTVYLCGAFWKAPTTGTDSQAGTLVHESSHFTRNGGTKDYAYGQAAAKSLATMDPDKAVMNADNHEYFSENNPAQS", "length": 348, "reference_go_mf": ["GO:0004222"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_82083ac368dcb2109c94"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_788_2e2h_assembly1", "enzyme_name": "DNA-directed RNA polymerase", "ec": ["2.7.7.6"], "controls": [{"chain": "A", "status": "reference_overlength", "selected": {"accession": "P04050", "alignment_score": 2740.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 1445], "sequence": "MVGQQYSSAPLRTVKEVQFGLFSPEEVRAISVAKIRFPETMDETQTRAKIGGLNDPRLGSIDRNLKCQTCQEGMNECPGHFGHIDLAKPVFHVGFIAKIKKVCECVCMHCGKLLLDEHNELMRQALAIKDSKKRFAAIWTLCKTKMVCETDVPSEDDPTQLVSRGGCGNTQPTIRKDGLKLVGSWKKDRATGDADEPELRVLSTEEILNIFKHISVKDFTSLGFNEVFSRPEWMILTCLPVPPPPVRPSISFNESQRGEDDLTFKLADILKANISLETLEHNGAPHHAIEEAESLLQFHVATYMDNDIAGQPQALQKSGRPVKSIRARLKGKEGRIRGNLMGKRVDFSARTVISGDPNLELDQVGVPKSIAKTLTYPEVVTPYNIDRLTQLVRNGPNEHPGAKYVIRDSGDRIDLRYSKRAGDIQLQYGWKVERHIMDNDPVLFNRQPSLHKMSMMAHRVKVIPYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPCMGIVQDTLCGIRKLTLRDTFIELDQVLNMLYWVPDWDGVIPTPAIIKPKPLWSGKQILSVAIPNGIHLQRFDEGTTLLSPKDNGMLIIDGQIIFGVVEKKTVGSSNGGLIHVVTREKGPQVCAKLFGNIQKVVNFWLLHNGFSTGIGDTIADGPTMREITETIAEAKKKVLDVTKEAQANLLTAKHGMTLRESFEDNVVRFLNEARDKAGRLAEVNLKDLNNVKQMVMAGSKGSFINIAQMSACVGQQSVEGKRIAFGFVDRTLPHFSKDDYSPESKGFVENSYLRGLTPQEFFFHAMGGREGLIDTAVKTAETGYIQRRLVKALEDIMVHYDNTTRNSLGNVIQFIYGEDGMDAAHIEKQSLDTIGGSDAAFEKRYRVDLLNTDHTLDPSLLESGSEILGDLKLQVLLDEEYKQLVKDRKFLREVFVDGEANWPLPVNIRRIIQNAQQTFHIDHTKPSDLTIKDIVLGVKDLQENLLVLRGKNEIIQNAQRDAVTLFCCLLRSRLATRRVLQEYRLTKQAFDWVLSNIEAQFLRSVVHPGEMVGVLAAQSIGEPATQMTLNTFHFAGVASKKVTSGVPRLKEILNVAKNMKTPSLTVYLEPGHAADQEQAKLIRSAIEHTTLKSVTIASEIYYDPDPRSTVIPEDEEIIQLHFSLLDEEAEQSFDQQSPWLLRLELDRAAMNDKDLTMGQVGERIKQTFKNDLFVIWSEDNDEKLIIRCRVVRPKSLDAETEAEEDHMLKKIENTMLENITLRGVENIERVVMMKYDRKVPSPTGEYVKEPEWVLETDGVNLSEVMTVPGIDPTRIYTNSFIDIMEVLGIEAGRAALYKEVYNVIASDGSYVNYRHMALLVDVMTTQGGLTSVTRHGFNRSNTGALMRCSFEETVEILFEAGASAELDDCRGVSENVILGQMAPIGTGAFDVMIDEESLVKYMPEQKITEIEDGQDGGVTPYSNESGLVNADLDVKDELMFSPLVDSGSNDAMAGGFTAYGGADYGEATSPFGAYGEAPTSPGFGVSSPGFSPTSPTYSPTSPAYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPAYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPGYSPGSPAYSPKQDEQKHNENENSR", "length": 1733, "reference_go_mf": ["GO:0003677", "GO:0003899"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}, {"chain": "B", "status": "reference_mapping_uncertain", "selected": {"accession": "P04050", "alignment_score": 9.0, "observed_coverage": 0.005474452554744526, "aligned_identity": 0.8333333333333334, "canonical_span": [778, 784], "sequence": "MVGQQYSSAPLRTVKEVQFGLFSPEEVRAISVAKIRFPETMDETQTRAKIGGLNDPRLGSIDRNLKCQTCQEGMNECPGHFGHIDLAKPVFHVGFIAKIKKVCECVCMHCGKLLLDEHNELMRQALAIKDSKKRFAAIWTLCKTKMVCETDVPSEDDPTQLVSRGGCGNTQPTIRKDGLKLVGSWKKDRATGDADEPELRVLSTEEILNIFKHISVKDFTSLGFNEVFSRPEWMILTCLPVPPPPVRPSISFNESQRGEDDLTFKLADILKANISLETLEHNGAPHHAIEEAESLLQFHVATYMDNDIAGQPQALQKSGRPVKSIRARLKGKEGRIRGNLMGKRVDFSARTVISGDPNLELDQVGVPKSIAKTLTYPEVVTPYNIDRLTQLVRNGPNEHPGAKYVIRDSGDRIDLRYSKRAGDIQLQYGWKVERHIMDNDPVLFNRQPSLHKMSMMAHRVKVIPYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPCMGIVQDTLCGIRKLTLRDTFIELDQVLNMLYWVPDWDGVIPTPAIIKPKPLWSGKQILSVAIPNGIHLQRFDEGTTLLSPKDNGMLIIDGQIIFGVVEKKTVGSSNGGLIHVVTREKGPQVCAKLFGNIQKVVNFWLLHNGFSTGIGDTIADGPTMREITETIAEAKKKVLDVTKEAQANLLTAKHGMTLRESFEDNVVRFLNEARDKAGRLAEVNLKDLNNVKQMVMAGSKGSFINIAQMSACVGQQSVEGKRIAFGFVDRTLPHFSKDDYSPESKGFVENSYLRGLTPQEFFFHAMGGREGLIDTAVKTAETGYIQRRLVKALEDIMVHYDNTTRNSLGNVIQFIYGEDGMDAAHIEKQSLDTIGGSDAAFEKRYRVDLLNTDHTLDPSLLESGSEILGDLKLQVLLDEEYKQLVKDRKFLREVFVDGEANWPLPVNIRRIIQNAQQTFHIDHTKPSDLTIKDIVLGVKDLQENLLVLRGKNEIIQNAQRDAVTLFCCLLRSRLATRRVLQEYRLTKQAFDWVLSNIEAQFLRSVVHPGEMVGVLAAQSIGEPATQMTLNTFHFAGVASKKVTSGVPRLKEILNVAKNMKTPSLTVYLEPGHAADQEQAKLIRSAIEHTTLKSVTIASEIYYDPDPRSTVIPEDEEIIQLHFSLLDEEAEQSFDQQSPWLLRLELDRAAMNDKDLTMGQVGERIKQTFKNDLFVIWSEDNDEKLIIRCRVVRPKSLDAETEAEEDHMLKKIENTMLENITLRGVENIERVVMMKYDRKVPSPTGEYVKEPEWVLETDGVNLSEVMTVPGIDPTRIYTNSFIDIMEVLGIEAGRAALYKEVYNVIASDGSYVNYRHMALLVDVMTTQGGLTSVTRHGFNRSNTGALMRCSFEETVEILFEAGASAELDDCRGVSENVILGQMAPIGTGAFDVMIDEESLVKYMPEQKITEIEDGQDGGVTPYSNESGLVNADLDVKDELMFSPLVDSGSNDAMAGGFTAYGGADYGEATSPFGAYGEAPTSPGFGVSSPGFSPTSPTYSPTSPAYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPAYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPGYSPGSPAYSPKQDEQKHNENENSR", "length": 1733, "reference_go_mf": ["GO:0003677", "GO:0003899"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_789_1nbf_assembly1", "enzyme_name": "ubiquitinyl hydrolase 1 (peptidase C19 type)", "ec": ["3.4.19.12"], "controls": [{"chain": "A", "status": "reference_overlength", "selected": {"accession": "Q93009", "alignment_score": 694.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [207, 554], "sequence": "MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN", "length": 1102, "reference_go_mf": ["GO:0004843", "GO:0004197", "GO:0101005", "GO:0140950", "GO:0140936", "GO:1990380", "GO:0002039"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": [{"accession": "P0CG48", "alignment_score": 7.0, "observed_coverage": 0.01440922190201729, "aligned_identity": 0.8, "canonical_span": [29, 34], "length": 685, "reference_go_mf": ["GO:0031386", "GO:0003723"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_78_1al6_assembly1", "enzyme_name": "citrate (Si)-synthase", "ec": ["2.3.3.1"], "controls": [{"chain": "A", "status": "reference_nonstandard", "selected": {"accession": "P23007", "alignment_score": 770.0, "observed_coverage": 0.9770114942528736, "aligned_identity": 0.9482352941176471, "canonical_span": [2, 430], "sequence": "ASSTNLKDVLAALIPKEQARIKTFRQQHGGTALGQITVDMSYGGMRGMKGLVYETSVLDPDEGIRFRGFSIPECQKLLPKGGXGGEPLPEGLFWLLVTGQIPTGAQVSWLSKEWAKRAALPSHVVTMLDNFPTNLHPMSQLSAAITALNSESNFARAYAEGILRTKYWEMVYESAMDLIAKLPCVAAKIYRNLYRAGSSIGAIDSKLDWSHNFTNMLGYTDAQFTELMRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQEVLGWLAQLQKAXXXAGADASLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYTCQREFALKHLPGDPMFKLVAQLYKIVPNVLLEQGAAANPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWSRALGFPLERPKSMSTDGLIAL", "length": 433, "reference_go_mf": ["GO:0036440", "GO:0042802"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_791_1fr2_assembly1", "enzyme_name": "colicin-E9", "ec": ["3.1.21.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P09883", "alignment_score": 262.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [449, 580], "sequence": "MSGGDGRGHNTGAHSTSGNINGGPTGIGVSGGASDGSGWSSENNPWGGGSGSGIHWGGGSGRGNGGGNGNSGGGSGTGGNLSAVAAPVAFGFPALSTPGAGGLAVSISASELSAAIAGIIAKLKKVNLKFTPFGVVLSSLIPSEIAKDDPNMMSKIVTSLPADDITESPVSSLPLDKATVNVNVRVVDDVKDERQNISVVSGVPMSVPVVDAKPTERPGVFTASIPGAPVLNISVNDSTPAVQTLSPGVTNNTDKDVRPAGFTQGGNTRDAVIRFPKDSGHNAVYVSVSDVLSPDQVKQRQDEENRRQQEWDATHPVEAAERNYERARAELNQANEDVARNQERQAKAVQVYNSRKSELDAANKTLADAIAEIKQFNRFAHDPMAGGHRMWQMAGLKAQRAQTDVNNKQAAFDAAAKEKSDADAALSAAQERRKQKENKEKDAKDKLDKESKRNKPGKATGKGKPVGDKWLDDAGKDSGAPIPDRIADKLRDKEFKSFDDFRKAVWEEVSKDPELSKNLNPSNKSSVSKGYSPFTPKNQQVGGRKVYELHHDKPISQGGEVYDMDNIRVTTPKRHIDIHRGK", "length": 582, "reference_go_mf": ["GO:0004519", "GO:0019904"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_98586c87e74a98e21c66"}, "alternative_alignments": [{"accession": "P13479", "alignment_score": 6.0, "observed_coverage": 0.022900763358778626, "aligned_identity": 1.0, "canonical_span": [18, 21], "length": 86, "reference_go_mf": ["GO:0019904", "GO:0015643"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_792_1qfn_assembly1", "enzyme_name": "protein disulfide oxidoreductase", "ec": ["1.8.4.-"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P68688", "alignment_score": 167.0, "observed_coverage": 1.0, "aligned_identity": 0.9882352941176471, "canonical_span": [0, 85], "sequence": "MQTVIFGRSGCPYCVRAKDLAEKLSNERDDFQYQYVDIRAEGITKEDLQQKAGKPVETVPQIFVDQQHIGGYTDFAAWVKENLDA", "length": 85, "reference_go_mf": ["GO:0015036", "GO:0009055", "GO:0019153", "GO:0015035"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_f1008c09621c58de99aa"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_793_1qwn_assembly1", "enzyme_name": "mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase", "ec": ["3.2.1.114"], "controls": [{"chain": "A", "status": "reference_overlength", "selected": {"accession": "Q24451", "alignment_score": 2025.0, "observed_coverage": 1.0, "aligned_identity": 0.9990138067061144, "canonical_span": [93, 1107], "sequence": "MLRIRRRFALVICSGCLLVFLSLYIILNFAAPAATQIKPNYENIENKLHELENGLQEHGEEMRNLRARLAETSNRDDPIRPPLKVARSPRPGQCQDVVQDVPNVDVQMLELYDRMSFKDIDGGVWKQGWNIKYDPLKYNAHHKLKVFVVPHSHNDPGWIQTFEEYYQHDTKHILSNALRHLHDNPEMKFIWAEISYFARFYHDLGENKKLQMKSIVKNGQLEFVTGGWVMPDEANSHWRNVLLQLTEGQTWLKQFMNVTPTASWAIDPFGHSPTMPYILQKSGFKNMLIQRTHYSVKKELAQQRQLEFLWRQIWDNKGDTALFTHMMPFYSYDIPHTCGPDPKVCCQFDFKRMGSFGLSCPWKVPPRTISDQNVAARSDLLVDQWKKKAELYRTNVLLIPLGDDFRFKQNTEWDVQRVNYERLFEHINSQAHFNVQAQFGTLQEYFDAVHQAERAGQAEFPTLSGDFFTYADRSDNYWSGYYTSRPYHKRMDRVLMHYVRAAEMLSAWHSWDGMARIEERLEQARRELSLFQHHDGITGTAKTHVVVDYEQRMQEALKACQMVMQQSVYRLLTKPSIYSPDFSFSYFTLDDSRWPGSGVEDSRTTIILGEDILPSKHVVMHNTLPHWREQLVDFYVSSPFVSVTDLANNPVEAQVSPVWSWHHDTLTKTIHPQGSTTKYRIIFKARVPPMGLATYVLTISDSKPEHTSYASNLLLRKNPTSLPLGQYPEDVKFGDPREISLRVGNGPTLAFSEQGLLKSIQLTQDSPHVPVHFKFLKYGVRSHGDRSGAYLFLPNGPASPVELGQPVVLVTKGKLESSVSVGLPSVVHQTIMRGGAPEIRNLVDIGSLDNTEIVMRLETHIDSGDIFYTDLNGLQFIKRRRLDKLPLQANYYPIPSGMFIEDANTRLTLLTGQPLGGSSLASGELEIMQDRRLASDDERGLGQGVLDNKPVLHIYRLVLEKVNNCVRPSELHPAGYLTSAAHKASQSLLDPLDKFIFAENEWIGAQGQFGGDHPSAREDLDVSVMRRLTKSSAKTQRVGYVLHRTNLMQCGTPEEHTQKLDVCHLLPNVARCERTTLTFLQNLEHLDGMVAPEVCPMETAAYVSSHSS", "length": 1108, "reference_go_mf": ["GO:0030246", "GO:0015923", "GO:0004572"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_794_1jh6_assembly1", "enzyme_name": "2',3'-cyclic-nucleotide 3'-phosphodiesterase", "ec": ["3.1.4.37"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "O04147", "alignment_score": 362.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 181], "sequence": "MEEVKKDVYSVWALPDEESEPRFKKLMEALRSEFTGPRFVPHVTVAVSAYLTADEAKKMFESACDGLKAYTATVDRVSTGTFFFQCVFLLLQTTPEVMEAGEHCKNHFNCSTTTPYMPHLSLLYAELTEEEKKNAQEKAYTLDSSLDGLSFRLNRLALCKTDTEDKTLETWETVAVCNLNP", "length": 181, "reference_go_mf": ["GO:0004113", "GO:0004112"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_da7921f33892a240bdef"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_795_1wnw_assembly2", "enzyme_name": "heme oxygenase (biliverdin-producing)", "ec": ["1.14.14.18"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P71119", "alignment_score": 402.0, "observed_coverage": 1.0, "aligned_identity": 0.9714285714285714, "canonical_span": [5, 215], "sequence": "MTTATAGLAVELKQSTAQAHEKAEHSTFMSDLLEGRLGVAEFTRLQEQAWLFYTALEQAADAVRASGFAESLLDPALNRAEVLARDLDKLNDGSEWRSRITASPAVIDYVNRLEEIRDNVDGPALVAHHYVRYLGDLSGGQVIARMMQRHYGVDPEALGFYHFEGIAKLKVYKDEYREKLNNLELSDEQRENLLKEATDAFVFNHQVFADLGKGL", "length": 215, "reference_go_mf": ["GO:0020037", "GO:0004392"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_9c6160b0a48d81201bdf"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_796_1fa0_assembly1", "enzyme_name": "polynucleotide adenylyltransferase", "ec": ["2.7.7.19"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P29468", "alignment_score": 1006.5, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [2, 523], "sequence": "MSSQKVFGITGPVSTVGATAAENKLNDSLIQELKKEGSFETEQETANRVQVLKILQELAQRFVYEVSKKKNMSDGMARDAGGKIFTYGSYRLGVHGPGSDIDTLVVVPKHVTREDFFTVFDSLLRERKELDEIAPVPDAFVPIIKIKFSGISIDLICARLDQPQVPLSLTLSDKNLLRNLDEKDLRALNGTRVTDEILELVPKPNVFRIALRAIKLWAQRRAVYANIFGFPGGVAWAMLVARICQLYPNACSAVILNRFFIILSEWNWPQPVILKPIEDGPLQVRVWNPKIYAQDRSHRMPVITPAYPSMCATHNITESTKKVILQEFVRGVQITNDIFSNKKSWANLFEKNDFFFRYKFYLEITAYTRGSDEQHLKWSGLVESKVRLLVMKLEVLAGIKIAHPFTKPFESSYCCPTEDDYEMIQDKYGSHKTETALNALKLVTDENKEEESIKDAPKAYLSTMYIGLDFNIENKKEKVDIHIPCTEFVNLCRSFNEDYGDHKVFNLALRFVKGYDLPDEVFDENEKRPSKKSKRKNLDARHETVKRSKSDAASGDNINGTTAAVDVN", "length": 568, "reference_go_mf": ["GO:0005524", "GO:0000287", "GO:1990817", "GO:0003723"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_6949a5be94fcf14afb21"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_798_1rtf_assembly1", "enzyme_name": "t-plasminogen activator", "ec": ["3.4.21.68"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00750", "alignment_score": 468.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [310, 562], "sequence": "MDAMKRGLCCVLLLCGAVFVSPSQEIHARFRRGARSYQVICRDEKTQMIYQQHQSWLRPVLRSNRVEYCWCNSGRAQCHSVPVKSCSEPRCFNGGTCQQALYFSDFVCQCPEGFAGKCCEIDTRATCYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGNHNYCRNPDRDSKPWCYVFKAGKYSSEFCSTPACSEGNSDCYFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQNPSAQALGLGKHNYCRNPDGDAKPWCHVLKNRRLTWEYCDVPSCSTCGLRQYSQPQFRIKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAAHCFQERFPPHHLTVILGRTYRVVPGEEEQKFEVEKYIVHKEFDDDTYDNDIALLQLKSDSSRCAQESSVVRTVCLPPADLQLPDWTECELSGYGKHEALSPFYSERLKEAHVRLYPSSRCTSQHLLNRTVTDNMLCAGDTRSGGPQANLHDACQGDSGGPLVCLNDGRMTLVGIISWGLGCGQKDVPGVYTKVTNYLDWIRDNMRP", "length": 562, "reference_go_mf": ["GO:0051219", "GO:0004252", "GO:0005102"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_4d29fd09ba426cc617b6"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_799_1f48_assembly1", "enzyme_name": "arsenite-transporting ATPase", "ec": ["7.3.2.7"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P08690", "alignment_score": 1051.5, "observed_coverage": 0.9945255474452555, "aligned_identity": 0.998165137614679, "canonical_span": [0, 583], "sequence": "MQFLQNIPPYLFFTGKGGVGKTSISCATAIRLAEQGKRVLLVSTDPASNVGQVFSQTIGITIQAIASVPGLSALEIDPQAAAQQYRARIVDPIKGVLPDDVVSSINEQLSGACTTEIAAFDEFTGLLTDASLLTRFDHIIFDTAPTGHTIRLLQLPGAWSSFIDSNPEGASCLGPMAGLEKQREQYAYAVEALSDPKRTRLVLVARLQKSTLQEVARTHLELAAIGLKNQYLVINGVLPKTEAANDTLAAAIWEREQEALANLPADLAGLPTDTLFLQPVNMVGVSALSRLLSTQPVASPSSDEYLQQRPDIPSLSALVDDIARNEHGLIMLMGKGGVGKTTMAAAIAVRLADMGFDVHLTTSDPAAHLSMTLNGSLNNLQVSRIDPHEETERYRQHVLETKGKELDEAGKRLLEEDLRSPCTEEIAVFQAFSRVIREAGKRFVVMDTAPTGHTLLLLDATGAYHREIAKKMGEKGHFTTPMMLLQDPERTKVLLVTLPETTPVLEAANLQADLERAGIHPWGWIINNSLSIADTRSPLLRMRAQQELPQIESVKRQHASRVALVPVLASEPTGIDKLKQLAG", "length": 583, "reference_go_mf": ["GO:0005524", "GO:0016887", "GO:0015446"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_07b4a11455f7d051fae9"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_7_5icd_assembly1", "enzyme_name": "isocitrate dehydrogenase (NADP+)", "ec": ["1.1.1.42"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P08200", "alignment_score": 828.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [2, 416], "sequence": "MESKVVVPAQGKKITLQNGKLNVPENPIIPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAETLDLIREYRVAIKGPLTTPVGGGIRSLNVALRQELDLYICLRPVRYYQGTPSPVKHPELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGELIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQVGGIGIAPGANIGDECALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRHMGWTEAADLIVKGMEGAINAKTVTYDFERLMDGAKLLKCSEFGDAIIENM", "length": 416, "reference_go_mf": ["GO:0097216", "GO:0004450", "GO:0000287", "GO:0051287"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_42155a6012693fa5bb26"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P08200", "alignment_score": 828.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [2, 416], "sequence": "MESKVVVPAQGKKITLQNGKLNVPENPIIPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAETLDLIREYRVAIKGPLTTPVGGGIRSLNVALRQELDLYICLRPVRYYQGTPSPVKHPELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGELIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQVGGIGIAPGANIGDECALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRHMGWTEAADLIVKGMEGAINAKTVTYDFERLMDGAKLLKCSEFGDAIIENM", "length": 416, "reference_go_mf": ["GO:0097216", "GO:0004450", "GO:0000287", "GO:0051287"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_42155a6012693fa5bb26"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_803_1o04_assembly1", "enzyme_name": "aldehyde dehydrogenase (NAD+) (class 2)", "ec": ["1.2.1.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P05091", "alignment_score": 985.0, "observed_coverage": 1.0, "aligned_identity": 0.9979757085020243, "canonical_span": [23, 517], "sequence": "MLRAAARFGPRLGRRLLSAAATQAVPAPNQQPEVFCNQIFINNEWHDAVSRKTFPTVNPSTGEVICQVAEGDKEDVDKAVKAARAAFQLGSPWRRMDASHRGRLLNRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYHGKTIPIDGDFFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEIGRVIQVAAGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDIYDEFVERSVARAKSRVVGNPFDSKTEQGPQVDETQFKKILGYINTGKQEGAKLLCGGGIAADRGYFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKTIEEVVGRANNSTYGLAAAVFTKDLDKANYLSQALQAGTVWVNCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKTVTVKVPQKNS", "length": 517, "reference_go_mf": ["GO:0140087", "GO:0004029", "GO:0106435", "GO:0051287", "GO:0046857", "GO:0008957", "GO:0001758"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_c6dc987207be93233446"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_805_1x9y_assembly1", "enzyme_name": "staphopain", "ec": ["3.4.22.28"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0C1S6", "alignment_score": 673.0, "observed_coverage": 0.9884393063583815, "aligned_identity": 1.0, "canonical_span": [40, 393], "sequence": "MNSSCKTRVFNIISIIMVSMLILSLGAFANNNKAKADSHSKQLEINVKSDKVPQKVKDLAQQQFAGYAKALDKQSNAKTGKYELGEAFKIYKFNGEEDNSYYYPVIKDGKIVYTLTLSPKNKDDLNKSKEDMNYSVKISNFIAKDLDQIKDKNSNITVLTDEKGFYFEEDGKVRLVKATPLANNIKEKESAKTVSPQLKQELKTTVTPTKVEENEAIQEDQVQYENTLKNFKIREQQFDNSWCAGFSMAALLNATKNTDTYNAHDIMRTLYPEVSEQDLPNCATFPNQMIEYGKSQGRDIHYQEGVPSYNQVDQLTKDNVGIMILAQSVSQNPNDPHLGHALAVVGNAKINDQEKLIYWNPWDTELSIQDADSSLLHLSFNRDYNWYGSMIGY", "length": 393, "reference_go_mf": ["GO:0008234"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_6d1b12b284ec0b5d5028"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_806_1cvr_assembly1", "enzyme_name": "gingipain R", "ec": ["3.4.22.37"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P95493", "alignment_score": 825.0, "observed_coverage": 1.0, "aligned_identity": 0.9699074074074074, "canonical_span": [229, 661], "sequence": "MKKNFSRIVSIVAFSSLLGGMAFAQPAERGRNPQVRLLSAEQSMSKVQFRMDNLQFTGVQTSKGVAQVPTFTEGVNISEKGTPILPILSRSLAVSETRAMKVEVVSSKFIEKKDVLIAPSKGVISRAENPDQIPYVYGQSYNEDKFFPGEIATLSDPFILRDVRGQVVNFAPLQYNPVTKTLRIYTEIVVAVSETAEAGQNTISLVKNSTFTGFEDIYKSVFMNYEATRYTPVEEKENGRMIVIVPKKYEEDIEDFVDWKNQRGLRTEVKVAEDIASPVTANAIQQFVKQEYEKEGNDLTYVLLVGDHKDIPAKITPGIKSDQVYGQIVGNDHYNEVFIGRFSCESKEDLKTQIDRTIHYERNITTEDKWLGQALCIASAEGGPSADNGESDIQHENIIANLLTQYGYTKIIKCYDPGVTPKNIIDAFNGGISLANYTGHGSETAWGTSHFGTTHVKQLTNSNQLPFIFDVACVNGDFLYNVPCFAEALMRAQKDGKPTGTVAIIASTINQSWASPMRGQDEMNEILCEKHPNNIKRTFGGVTMNGMFAMVEKYKKDGEKMLDTWTVFGDPSLLVRTLVPTKMQVTAPANISASAQTFEVACDYNGAIATLSDDGDMVGTAIVKDGKAIIKLNESIADETNLTLTVVGYNKVTVIKDVKVEGTSIADVANDKPYTVAVSGKTITVESPAAGLTIFDMNGRRVATAKNRMVFEAQNGVYAVRIATEGKTYTEKVIVK", "length": 736, "reference_go_mf": ["GO:0005509", "GO:0004198"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_71ad86641ccbe57d9ac4"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_807_6u7t_assembly1", "enzyme_name": "adenine DNA glycosylase", "ec": ["3.2.2.31"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P83847", "alignment_score": 690.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [6, 360], "sequence": "MTRETERFPAREFQRDLLDWFARERRDLPWRKDRDPYKVWVSEVMLQQTRVETVIPYFEQFIDRFPTLEALADADEDEVLKAWEGLGYYSRVRNLHAAVKEVKTRYGGKVPDDPDEFSRLKGVGPYTVGAVLSLAYGVPEPAVDGNVMRVLSRLFLVTDDIAKPSTRKRFEQIVREIMAYENPGAFNEALIELGALVCTPRRPSCLLCPVQAYCQAFAEGVAEELPVKMKKTAVKQVPLAVAVLADDEGRVLIRKRDSTGLLANLWEFPSCETDGADGKEKLEQMVGEQYGLQVELTEPIVSFEHAFSHLVWQLTVFPGRLVHGGPVEEPYRLAPEDELKAYAFPVSHQRVWREYKEWASGVRRPD", "length": 366, "reference_go_mf": ["GO:0051539", "GO:0034039", "GO:0035485", "GO:0003677", "GO:0019104", "GO:0032357", "GO:0000701"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_1b67f455f7c8a41df1cf"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_808_1k32_assembly1", "enzyme_name": "tricorn protease", "ec": ["3.4.21.-"], "controls": [{"chain": "A", "status": "reference_overlength", "selected": {"accession": "P96086", "alignment_score": 2046.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [38, 1061], "sequence": "MPSLMSFGSCQWIDQGRFSRSLYRNFKTFKLHEMHGLCMPNLLLNPDIHGDRIIFVCCDDLWEHDLKSGSTRKIVSNLGVINNARFFPDGRKIAIRVMRGSSLNTADLYFYNGENGEIKRITYFSGKSTGRRMFTDVAGFDPDGNLIISTDAMQPFSSMTCLYRVENDGINFVPLNLGPATHILFADGRRVIGRNTFELPHWKGYRGGTRGKIWIEVNSGAFKKIVDMSTHVSSPVIVGHRIYFITDIDGFGQIYSTDLDGKDLRKHTSFTDYYPRHLNTDGRRILFSKGGSIYIFNPDTEKIEKIEIGDLESPEDRIISIPSKFAEDFSPLDGDLIAFVSRGQAFIQDVSGTYVLKVPEPLRIRYVRRGGDTKVAFIHGTREGDFLGIYDYRTGKAEKFEENLGNVFAMGVDRNGKFAVVANDRFEIMTVDLETGKPTVIERSREAMITDFTISDNSRFIAYGFPLKHGETDGYVMQAIHVYDMEGRKIFAATTENSHDYAPAFDADSKNLYYLSYRSLDPSPDRVVLNFSFEVVSKPFVIPLIPGSPNPTKLVPRSMTSEAGEYDLNDMYKRSSPINVDPGDYRMIIPLESSILIYSVPVHGEFAAYYQGAPEKGVLLKYDVKTRKVTEVKNNLTDLRLSADRKTVMVRKDDGKIYTFPLEKPEDERTVETDKRPLVSSIHEEFLQMYDEAWKLARDNYWNEAVAKEISERIYEKYRNLVPLCKTRYDLSNVIVEMQGEYRTSHSYEMGGTFTDKDPFRSGRIACDFKLDGDHYVVAKAYAGDYSNEGEKSPIFEYGIDPTGYLIEDIDGETVGAGSNIYRVLSEKAGTSARIRLSGKGGDKRDLMIDILDDDRFIRYRSWVEANRRYVHERSKGTIGYIHIPDMGMMGLNEFYRLFINESSYQGLIVDVRFNGGGFVSQLIIEKLMNKRIGYDNPRRGTLSPYPTNSVRGKIIAITNEYAGSDGDIFSFSFKKLGLGKLIGTRTWGGVVGITPKRRLIDGTVLTQPEFAFWFRDAGFGVENYGVDPDVEIEYAPHDYLSGKDPQIDYAIDALIEELRNWNEELPQRPS", "length": 1071, "reference_go_mf": ["GO:0008236"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_80_1c3c_assembly1", "enzyme_name": "adenylosuccinate lyase", "ec": ["4.3.2.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q9X0I0", "alignment_score": 840.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 430], "sequence": "MVERYSLSPMKDLWTEEAKYRRWLEVELAVTRAYEELGMIPKGVTERIRNNAKIDVELFKKIEEKTNHDVVAFVEGIGSMIGEDSRFFHYGLTSSDVLDTANSLALVEAGKILLESLKEFCDVLWEVANRYKHTPTIGRTHGVHAEPTSFGLKVLGWYSEMKRNVQRLERAIEEVSYGKISGAVGNYANVPPEVEEKALSYLGLKPEPVSTQVVPRDRHAFYLSTLAIVAAGIERIAVEIRHLQRTEVLEVEEPFRKGQRGSSAMPHKKNPITCERLTGLSRMMRAYVDPSLENIALWHERDISHSSVERYVFPDATQTLYYMIVTATNVVRNMKVNEERMKKNIDLTKGLVFSQRVLLKLIEKGLTRKEAYDIVQRNALKTWNSEKHFLEYLLEDEEVKKLVTKEELEELFDISYYLKHVDHIFERFEKE", "length": 431, "reference_go_mf": ["GO:0070626", "GO:0004018"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_8022d24de5d7999d26db"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "Q9X0I0", "alignment_score": 840.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 430], "sequence": "MVERYSLSPMKDLWTEEAKYRRWLEVELAVTRAYEELGMIPKGVTERIRNNAKIDVELFKKIEEKTNHDVVAFVEGIGSMIGEDSRFFHYGLTSSDVLDTANSLALVEAGKILLESLKEFCDVLWEVANRYKHTPTIGRTHGVHAEPTSFGLKVLGWYSEMKRNVQRLERAIEEVSYGKISGAVGNYANVPPEVEEKALSYLGLKPEPVSTQVVPRDRHAFYLSTLAIVAAGIERIAVEIRHLQRTEVLEVEEPFRKGQRGSSAMPHKKNPITCERLTGLSRMMRAYVDPSLENIALWHERDISHSSVERYVFPDATQTLYYMIVTATNVVRNMKVNEERMKKNIDLTKGLVFSQRVLLKLIEKGLTRKEAYDIVQRNALKTWNSEKHFLEYLLEDEEVKKLVTKEELEELFDISYYLKHVDHIFERFEKE", "length": 431, "reference_go_mf": ["GO:0070626", "GO:0004018"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_8022d24de5d7999d26db"}, "alternative_alignments": []}, {"chain": "C", "status": "assigned", "selected": {"accession": "Q9X0I0", "alignment_score": 840.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 430], "sequence": "MVERYSLSPMKDLWTEEAKYRRWLEVELAVTRAYEELGMIPKGVTERIRNNAKIDVELFKKIEEKTNHDVVAFVEGIGSMIGEDSRFFHYGLTSSDVLDTANSLALVEAGKILLESLKEFCDVLWEVANRYKHTPTIGRTHGVHAEPTSFGLKVLGWYSEMKRNVQRLERAIEEVSYGKISGAVGNYANVPPEVEEKALSYLGLKPEPVSTQVVPRDRHAFYLSTLAIVAAGIERIAVEIRHLQRTEVLEVEEPFRKGQRGSSAMPHKKNPITCERLTGLSRMMRAYVDPSLENIALWHERDISHSSVERYVFPDATQTLYYMIVTATNVVRNMKVNEERMKKNIDLTKGLVFSQRVLLKLIEKGLTRKEAYDIVQRNALKTWNSEKHFLEYLLEDEEVKKLVTKEELEELFDISYYLKHVDHIFERFEKE", "length": 431, "reference_go_mf": ["GO:0070626", "GO:0004018"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_8022d24de5d7999d26db"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_810_2bif_assembly1", "enzyme_name": "fructose-2,6-bisphosphate 2-phosphatase", "ec": ["3.1.3.46"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P25114", "alignment_score": 852.0, "observed_coverage": 1.0, "aligned_identity": 0.9907407407407407, "canonical_span": [37, 469], "sequence": "MASPRELTQNPLKKIWMPYSNGRPALHASQRGVCMTNCPTLIVMVGLPARGKTYISKKLTRYLNWIGVPTREFNVGQYRRDMVKTYKSFEFFLPDNEEGLKIRKQCALAALNDVRKFLSEEGGHVAVFDATNTTRERRAMIFNFGEQNGYKTFFVESICVDPEVIAANIVQVKLGSPDYVNRDSDEATEDFMRRIECYENSYESLDEEQDRDLSYIKIMDVGQSYVVNRVADHIQSRIVYYLMNIHVTPRSIYLCRHGESELNLKGRIGGDPGLSPRGREFSKHLAQFISDQNIKDLKVWTSQMKRTIQTAEALSVPYEQWKVLNEIDAGVCEEMTYEEIQDHYPLEFALRDQDKYRYRYPKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKAAEELPYLKCPLHTVLKLTPVAYGCKVESIFLNVAAVNTHRDRPQNVDISRPSEEALVTVPAHQ", "length": 469, "reference_go_mf": ["GO:0003873", "GO:0005524", "GO:0004331"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_1359fdc8ef7ad8264446"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_812_1q91_assembly1", "enzyme_name": "5'-nucleotidase (mitochondrial)", "ec": ["3.1.3.5"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q9NPB1", "alignment_score": 388.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [33, 227], "sequence": "MIRLGGWCARRLCSAAVPAGRRGAAGGLGLAGGRALRVLVDMDGVLADFEGGFLRKFRARFPDQPFIALEDRRGFWVSEQYGRLRPGLSEKAISIWESKNFFFELEPLPGAVEAVKEMASLQNTDVFICTSPIKMFKYCPYEKYAWVEKYFGPDFLEQIVLTRDKTVVSADLLIDDRPDITGAEPTPSWEHVLFTACHNQHLQLQPPRRRLHSWADDWKAILDSKRPC", "length": 228, "reference_go_mf": ["GO:0008254", "GO:0002953", "GO:0008253", "GO:0008252"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_0ffbbed23b94a7616021"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_814_1glo_assembly1", "enzyme_name": "cathepsin S", "ec": ["3.4.22.27"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P25774", "alignment_score": 428.0, "observed_coverage": 1.0, "aligned_identity": 0.9907834101382489, "canonical_span": [114, 331], "sequence": "MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI", "length": 331, "reference_go_mf": ["GO:0005518", "GO:0004197", "GO:0008234", "GO:0001968", "GO:0043236", "GO:0008233", "GO:0043394", "GO:0004252"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_acd1c3790427993ba8ee"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_815_1pau_assembly1", "enzyme_name": "caspase-3", "ec": ["3.4.22.56"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P42574", "alignment_score": 280.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [33, 173], "sequence": "MENTENSVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSGVDDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH", "length": 277, "reference_go_mf": ["GO:0004190", "GO:0004861", "GO:0004197", "GO:0005123", "GO:0008047", "GO:0008233", "GO:0016005", "GO:0002020", "GO:0044877"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_81962b47787bfaba7693"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_816_1nw9_assembly1", "enzyme_name": "caspase-9", "ec": ["3.4.22.62"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P55211", "alignment_score": 442.5, "observed_coverage": 1.0, "aligned_identity": 0.9957983193277311, "canonical_span": [139, 416], "sequence": "MDEADRRLLRRCRLRLVEELQVDQLWDALLSRELFRPHMIEDIQRAGSGSRRDQARQLIIDLETRGSQALPLFISCLEDTGQDMLASFLRTNRQAAKLSKPTLENLTPVVLRPEIRKPEVLRPETPRPVDIGSGGFGDVGALESLRGNADLAYILSMEPCGHCLIINNVNFCRESGLRTRTGSNIDCEKLRRRFSSLHFMVEVKGDLTAKKMVLALLELAQQDHGALDCCVVVILSHGCQASHLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLGGKPKLFFIQACGGEQKDHGFEVASTSPEDESPGSNPEPDATPFQEGLRTFDQLDAISSLPTPSDIFVSYSTFPGFVSWRDPKSGSWYVETLDDIFEQWAHSEDLQSLLLRVANAVSVKGIYKQMPGCFNFLRKKLFFKTS", "length": 416, "reference_go_mf": ["GO:0004197", "GO:0008047", "GO:0042802", "GO:0008233", "GO:0019901"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_4abebcd6fb389b5c4032"}, "alternative_alignments": [{"accession": "P98170", "alignment_score": 9.0, "observed_coverage": 0.025210084033613446, "aligned_identity": 0.8333333333333334, "canonical_span": [124, 130], "length": 497, "reference_go_mf": ["GO:0004869", "GO:0043027", "GO:0042802", "GO:0120283", "GO:0061630", "GO:0004842"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_817_1itx_assembly1", "enzyme_name": "chitinase (GH18, class II)", "ec": ["3.2.1.14"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P20533", "alignment_score": 838.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [32, 451], "sequence": "MINLNKHTAFKKTAKFFLGLSLLLSVIVPSFALQPATAEAADSYKIVGYYPSWAAYGRNYNVADIDPTKVTHINYAFADICWNGIHGNPDPSGPNPVTWTCQNEKSQTINVPNGTIVLGDPWIDTGKTFAGDTWDQPIAGNINQLNKLKQTNPNLKTIISVGGWTWSNRFSDVAATAATREVFANSAVDFLRKYNFDGVDLDWEYPVSGGLDGNSKRPEDKQNYTLLLSKIREKLDAAGAVDGKKYLLTIASGASATYAANTELAKIAAIVDWINIMTYDFNGAWQKISAHNAPLNYDPAASAAGVPDANTFNVAAGAQGHLDAGVPAAKLVLGVPFYGRGWDGCAQAGNGQYQTCTGGSSVGTWEAGSFDFYDLEANYINKNGYTRYWNDTAKVPYLYNASNKRFISYDDAESVGYKTAYIKSKGLGGAMFWELSGDRNKTLQNKLKADLPTGGTVPPVDTTAPSVPGNARSTGVTANSVTLAWNASTDNVGVTGYNVYNGANLATSVTGTTATISGLTAGTSYTFTIKAKDAAGNLSAASNAVTVSTTAQPGGDTQAPTAPTNLASTAQTTSSITLSWTASTDNVGVTGYDVYNGTALATTVTGTTATISGLAADTSYTFTVKAKDAAGNVSAASNAVSVKTAAETTNPGVSAWQVNTAYTAGQLVTYNGKTYKCLQPHTSLAGWEPSNVPALWQLQ", "length": 699, "reference_go_mf": ["GO:0030246", "GO:0008061", "GO:0008843"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_e3378761cbe3ab6bd86e"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_818_1qtn_assembly1", "enzyme_name": "caspase-8", "ec": ["3.4.22.61"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q14790", "alignment_score": 304.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [222, 374], "sequence": "MDFSRNLYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELLFRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSFKFLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKIINDYEEFSKERSSSLEGSPDEFSNGEELCGVMTISDSPREQDSESQTLDKVYQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHDDCTVEQIYEILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGLKCPSLAGKPKVFFIQACQGDNYQKGIPVETDSEEQPYLEMDLSSPQTRYIPDEADFLLGMATVNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEVNYEVSNKDDKKNMGKQMPQPTFTLRKKLVFPSD", "length": 479, "reference_go_mf": ["GO:0008656", "GO:0004197", "GO:0008234", "GO:0035877", "GO:0005123", "GO:0042802", "GO:0008233", "GO:0044877", "GO:0097110", "GO:0031625"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_a23099a3856f1e0ce5a8"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_819_2dbt_assembly1", "enzyme_name": "chitinase C", "ec": ["3.2.1.14"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "O50152", "alignment_score": 410.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [89, 294], "sequence": "MYRRVMSLLVALGAIVAALIVLPATTAQAATCATAWSSSSVYTNGGTVSYNGRNYTAKWWTQNERPGTSDVWADKGACGTGGEGPGGNNGFVVSEAQFNQMFPNRNAFYTYKGLTDALSAYPAFAKTGSDEVKKREAAAFLANVSHETGGLFYIKEVNEANYPHYCDTTQSYGCPAGQAAYYGRGPIQLSWNFNYKAAGDALGINLLANPYLVEQDPAVAWKTGLWYWNSQNGPGTMTPHNAIVNNAGFGETIRSINGALECNGGNPAQVQSRINKFTQFTQILGTTTGPNLSC", "length": 294, "reference_go_mf": ["GO:0030246", "GO:0004568"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_bfee2f0625c03cbbc0bd"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_81_3csm_assembly1", "enzyme_name": "chorismate mutase (AroQ)", "ec": ["5.4.99.5"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P32178", "alignment_score": 496.5, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 256], "sequence": "MDFTKPETVLNLQNIRDELVRMEDSIIFKFIERSHFATCPSVYEANHPGLEIPNFKGSFLDWALSNLEIAHSRIRRFESPDETPFFPDKIQKSFLPSINYPQILAPYAPEVNYNDKIKKVYIEKIIPLISKRDGDDKNNFGSVATRDIECLQSLSRRIHFGKFVAEAKFQSDIPLYTKLIKSKDVEGIMKNITNSAVEEKILERLTKKAEVYGVDPTNESGERRITPEYLVKIYKEIVIPITKEVEVEYLLRRLEE", "length": 256, "reference_go_mf": ["GO:0004106", "GO:0072545", "GO:0120284"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_2a597422a88e6b05f617"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_820_2bkr_assembly1", "enzyme_name": "Ulp1 peptidase", "ec": ["3.4.22.68"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q96LD8", "alignment_score": 413.0, "observed_coverage": 1.0, "aligned_identity": 0.985781990521327, "canonical_span": [0, 211], "sequence": "MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLITTLAKK", "length": 212, "reference_go_mf": ["GO:0008234", "GO:0019784"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_f59a86c8b15fd67c8ce8"}, "alternative_alignments": [{"accession": "Q15843", "alignment_score": 8.0, "observed_coverage": 0.018957345971563982, "aligned_identity": 1.0, "canonical_span": [29, 33], "length": 81, "reference_go_mf": ["GO:0031386", "GO:0031625"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_821_1i78_assembly1", "enzyme_name": "omptin", "ec": ["3.4.23.49"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P09169", "alignment_score": 585.0, "observed_coverage": 1.0, "aligned_identity": 0.98989898989899, "canonical_span": [20, 317], "sequence": "MRAKLLGIVLTTPIAISSFASTETLSFTPDNINADISLGTLSGKTKERVYLAEEGGRKVSQLDWKFNNAAIIKGAINWDLMPQISIGAAGWTTLGSRGGNMVDQDWMDSSNPGTWTDESRHPDTQLNYANEFDLNIKGWLLNEPNYRLGLMAGYQESRYSFTARGGSYIYSSEEGFRDDIGSFPNGERAIGYKQRFKMPYIGLTGSYRYEDFELGGTFKYSGWVESSDNDEHYDPGKRITYRSKVKDQNYYSVAVNAGYYVTPNAKVYVEGAWNRVTNKKGNTSLYDHNNNTSDYSKNGAGIENYNFITTAGLKYTF", "length": 317, "reference_go_mf": ["GO:0004190", "GO:0004175", "GO:0004252"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_f6456c7f47f45804ae5c"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_822_1i19_assembly2", "enzyme_name": "cholesterol oxidase", "ec": ["1.1.3.-"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q7SID9", "alignment_score": 1061.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [4, 561], "sequence": "STGPVAPLPTPPNFPNDIALFQQAYQNWSKEIMLDATWVCSPKTPQDVVRLANWAHEHDYKIRPRGAMHGWTPLTVEKGANVEKVILADTMTHLNGITVNTGGPVATVTAGAGASIEAIVTELQKHDLGWANLPAPGVLSIGGALAVNAHGAALPAVGQTTLPGHTYGSLSNLVTELTAVVWNGTTYALETYQRNDPRITPLLTNLGRCFLTSVTMQAGPNFRQRCQSYTDIPWRELFAPKGADGRTFEKFVAESGGAEAIWYPFTEKPWMKVWTVSPTKPDSSNEVGSLGSAGSLVGKPPQAREVSGPYNYIFSDNLPEPITDMIGAINAGNPGIAPLFGPAMYEITKLGLAATNANDIWGWSKDVQFYIKATTLRLTEGGGAVVTSRANIATVINDFTEWFHERIEFYRAKGEFPLNGPVEIRCCGLDQAADVKVPSVGPPTISATRPRPDHPDWDVAIWLNVLGVPGTPGMFEFYREMEQWMRSHYNNDDATFRPEWSKGWAFGPDPYTDNDIVTNKMRATYIEGVPTTENWDTARARYNQIDPHRVFTNGFMDKLLP", "length": 561, "reference_go_mf": ["GO:0071949", "GO:0016899"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_6777b21d51a03ff1349a"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_823_1mqw_assembly1", "enzyme_name": "ADP-ribose diphosphatase", "ec": ["3.6.1.13"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "O33199", "alignment_score": 400.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [4, 204], "sequence": "MAEHDFETISSETLHTGAIFALRRDQVRMPGGGIVTREVVEHFGAVAIVAMDDNGNIPMVYQYRHTYGRRLWELPAGLLDVAGEPPHLTAARELREEVGLQASTWQVLVDLDTAPGFSDESVRVYLATGLREVGRPEAHHEEADMTMGWYPIAEAARRVLRGEIVNSIAIAGVLAVHAVTTGFAQPRPLDTEWIDRPTAFAARRAER", "length": 207, "reference_go_mf": ["GO:0030145"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_6c7f631521f96b394c9d"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_825_1ahb_assembly1", "enzyme_name": "rRNA N-glycosylase", "ec": ["3.2.2.22"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P16094", "alignment_score": 492.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [23, 269], "sequence": "MSRFSVLSFLILAIFLGGSIVKGDVSFRLSGADPRSYGMFIKDLRNALPFREKVYNIPLLLPSVSGAGRYLLMHLFNYDGKTITVAVDVTNVYIMGYLADTTSYFFNEPAAELASQYVFRDARRKITLPYSGNYERLQIAAGKPREKIPIGLPALDSAISTLLHYDSTAAAGALLVLIQTTAEAARFKYIEQQIQERAYRDEVPSLATISLENSWSGLSKQIQLAQGNNGIFRTPIVLVDNKGNRVQITNVTSKVVTSNIQLLLNTRNIAEGDNGDVSTTHGFSSY", "length": 286, "reference_go_mf": ["GO:0030598"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_59e8b2256ae3686fd28b"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_826_1un1_assembly2", "enzyme_name": "xyloglucan:xyloglucosyl transferase", "ec": ["2.4.1.207"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q8GZD5", "alignment_score": 528.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [30, 294], "sequence": "MAAAYPWTLFLGMLVMVSGTMGAALRKPVDVAFGRNYVPTWAFDHIKYFNGGNEIQLHLDKYTGTGFQSKGSYLFGHFSMQMKLVPGDSAGTVTAFYLSSQNSEHDEIDFEFLGNRTGQPYILQTNVFTGGKGDREQRIYLWFDPTKEFHYYSVLWNMYMIVFLVDDVPIRVFKNCKDLGVKFPFNQPMKIYSSLWNADDWATRGGLEKTDWSKAPFIASYRSFHIDGCEASVEAKFCATQGARWWDQKEFQDLDAFQYRRLSWVRQKYTIYNYCTDRSRYPSMPPECKRDRDI", "length": 294, "reference_go_mf": ["GO:0004553", "GO:0030247", "GO:0016762"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_1e03015064275c0b95be"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_828_7nn9_assembly1", "enzyme_name": "exo-alpha-sialidase (GH34 Family)", "ec": ["3.2.1.18"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P03472", "alignment_score": 776.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [82, 470], "sequence": "MNPNQKILCTSATALVIGTIAVLIGITNLGLNIGLHLKPSCNCSHSQPEATNASQTIINNYYNDTNITQISNTNIQVEERAIRDFNNLTKGLCTINSWHIYGKDNAVRIGEDSDVLVTREPYVSCDPDECRFYALSQGTTIRGKHSNGTIHDRSQYRALISWPLSSPPTVYNSRVECIGWSSTSCHDGKTRMSICISGPNNNASAVIWYNRRPVTEINTWARNILRTQESECVCHNGVCPVVFTDGSATGPAETRIYYFKEGKILKWEPLAGTAKHIEECSCYGERAEITCTCRDNWQGSNRPVIRIDPVAMTHTSQYICSPVLTDNPRPNDPTVGKCNDPYPGNNNNGVKGFSYLDGVNTWLGRTISIASRSGYEMLKVPNALTDDKSKPTQGQTIVLNTDWSGYSGSFMDYWAEGECYRACFYVELIRGRPKEDKVWWTSNSIVSMCSSTEFLGQWDWPDGAKIEYFL", "length": 470, "reference_go_mf": ["GO:0004308", "GO:0046872"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_ba9326638a5169db369b"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_829_1v0e_assembly1", "enzyme_name": "endo-alpha-sialidase", "ec": ["3.2.1.129"], "controls": [{"chain": "A", "status": "reference_overlength", "selected": {"accession": "Q04830", "alignment_score": 1330.0, "observed_coverage": 0.9984984984984985, "aligned_identity": 1.0, "canonical_span": [245, 910], "sequence": "MSTITQFPSGNTQYRIEFDYLARTFVVVTLVNSSNPTLNRVLEVGRDYRFLNPTMIEMLVDQSGFDIVRIHRQTGTDLVVDFRNGSVLTASDLTTAELQAIHIAEEGRDQTVDLAKEYADAAGSSAGNAKDSEDEARRIAESIRAAGLIGYMTRRSFEKGYNVTTWSEVLLWEEDGDYYRWDGTLPKNVPAGSTPETSGGIGLGAWVSVGDAALRSQISNPEGAILYPELHRARWLDEKDARGWGAKGDGVTDDTAALTSALNDTPVGQKINGNGKTYKVTSLPDISRFINTRFVYERIPGQPLYYASEEFVQGELFKITDTPYYNAWPQDKAFVYENVIYAPYMGSDRHGVSRLHVSWVKSGDDGQTWSTPEWLTDLHPDYPTVNYHCMSMGVCRNRLFAMIETRTLAKNALTNCALWDRPMSRSLHLTGGITKAANQRYATIHVPDHGLFVGDFVNFSNSAVTGVSGDMTVATVIDKDNFTVLTPNQQTSDLNNAGKNWHMGTSFHKSPWRKTDLGLIPSVTEVHSFATIDNNGFAMGYHQGDVAPREVGLFYFPDAFNSPSNYVRRQIPSEYEPDASEPCIKYYDGVLYLITRGTRGDRLGSSLHRSRDIGQTWESLRFPHNVHHTTLPFAKVGDDLIMFGSERAENEWEAGAPDDRYKASYPRTFYARLNVNNWNADDIEWVNITDQIYQGGIVNSGVGVGSVVVKDNYIYYMFGGEDHFNPWTYGDNSAKDPFKSDGHPSDLYCYKMKIGPDNRVSRDFRYGAVPNRAVPVFFDTNGVRTVPAPMEFTGDLGLGHVTIRASTSSNIRSEVLMEGEYGFIGKSIPTDNPAGQRIIFCGGEGTSSTTGAQITLYGANNTDSRRIVYNGDEHLFQSADVKPYNDNVTALGGPSNRFTTAYLGSNPIVTSNGERKTEPVVFDDAFLDAWGDVHYIMYQWLDAVQLKGNDARIHFGVIAQQIRDVFIAHGLMDENSTNCRYAVLCYDKYPRMTDTVFSHNEIVEHTDEEGNVTTTEEPVYTEVVIHEEGEEWGVRPDGIFFAEAAYQRRKLERIEARLSALEQK", "length": 1064, "reference_go_mf": ["GO:0016996", "GO:0042802"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_82_1jxa_assembly1", "enzyme_name": "glutamine-fructose-6-phosphate transaminase (isomerizing)", "ec": ["2.6.1.16"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P17169", "alignment_score": 1213.0, "observed_coverage": 1.0, "aligned_identity": 0.9983552631578947, "canonical_span": [1, 609], "sequence": "MCGIVGAIAQRDVAEILLEGLRRLEYRGYDSAGLAVVDAEGHMTRLRRLGKVQMLAQAAEEHPLHGGTGIAHTRWATHGEPSEVNAHPHVSEHIVVVHNGIIENHEPLREELKARGYTFVSETDTEVIAHLVNWELKQGGTLREAVLRAIPQLRGAYGTVIMDSRHPDTLLAARSGSPLVIGLGMGENFIASDQLALLPVTRRFIFLEEGDIAEITRRSVNIFDKTGAEVKRQDIESNLQYDAGDKGIYRHYMQKEIYEQPNAIKNTLTGRISHGQVDLSELGPNADELLSKVEHIQILACGTSYNSGMVSRYWFESLAGIPCDVEIASEFRYRKSAVRRNSLMITLSQSGETADTLAGLRLSKELGYLGSLAICNVPGSSLVRESDLALMTNAGTEIGVASTKAFTTQLTVLLMLVAKLSRLKGLDASIEHDIVHGLQALPSRIEQMLSQDKRIEALAEDFSDKHHALFLGRGDQYPIALEGALKLKEISYIHAEAYAAGELKHGPLALIDADMPVIVVAPNNELLEKLKSNIEEVRARGGQLYVFADQDAGFVSSDNMHIIEMPHVEEVIAPIFYTVPLQLLAYHVALIKGTDVDQPRNLAKSVTVE", "length": 609, "reference_go_mf": ["GO:0097367", "GO:0004360"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_dff406f4a44eb698bf1a"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P17169", "alignment_score": 1213.0, "observed_coverage": 1.0, "aligned_identity": 0.9983552631578947, "canonical_span": [1, 609], "sequence": "MCGIVGAIAQRDVAEILLEGLRRLEYRGYDSAGLAVVDAEGHMTRLRRLGKVQMLAQAAEEHPLHGGTGIAHTRWATHGEPSEVNAHPHVSEHIVVVHNGIIENHEPLREELKARGYTFVSETDTEVIAHLVNWELKQGGTLREAVLRAIPQLRGAYGTVIMDSRHPDTLLAARSGSPLVIGLGMGENFIASDQLALLPVTRRFIFLEEGDIAEITRRSVNIFDKTGAEVKRQDIESNLQYDAGDKGIYRHYMQKEIYEQPNAIKNTLTGRISHGQVDLSELGPNADELLSKVEHIQILACGTSYNSGMVSRYWFESLAGIPCDVEIASEFRYRKSAVRRNSLMITLSQSGETADTLAGLRLSKELGYLGSLAICNVPGSSLVRESDLALMTNAGTEIGVASTKAFTTQLTVLLMLVAKLSRLKGLDASIEHDIVHGLQALPSRIEQMLSQDKRIEALAEDFSDKHHALFLGRGDQYPIALEGALKLKEISYIHAEAYAAGELKHGPLALIDADMPVIVVAPNNELLEKLKSNIEEVRARGGQLYVFADQDAGFVSSDNMHIIEMPHVEEVIAPIFYTVPLQLLAYHVALIKGTDVDQPRNLAKSVTVE", "length": 609, "reference_go_mf": ["GO:0097367", "GO:0004360"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_dff406f4a44eb698bf1a"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_830_2bx4_assembly1", "enzyme_name": "ubiquitinyl hydrolase 1 (peptidase C30 type)", "ec": ["3.4.19.12"], "controls": [{"chain": "A", "status": "reference_overlength", "selected": {"accession": "P0C6X7", "alignment_score": 596.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [3242, 3540], "sequence": "MESLVLGVNEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKNGTCGLVELEKGVLPQLEQPYVFIKRSDALSTNHGHKVVELVAEMDGIQYGRSGITLGVLVPHVGETPIAYRNVLLRKNGNKGAGGHSYGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGGAVTRYVDNNFCGPDGYPLDCIKDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHEHEIAWFTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRIRSVYPVASPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEHCGTENLVIEGPTTCGYLPTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKRAYWVPRASADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILASFSASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPLCGFPSQAAGVIRSIFARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAYVTGGLVQQTSQWLSNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIVKGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQCIRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVGTPVCVNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNVRITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDEWSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTEDDYQGLPLEFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKSVVQKPVDVKPKIKACIDEVTTTLEETKFLTNKLLLFADINGKLYHDSQNMLRGEDMSFLEKDAPYMVGDVITSGDITCVVIPSKKAGGTTEMLSRALKKVPVDEYITTYPGQGCAGYTLEEAKTALKKCKSAFYVLPSEAPNAKEEILGTVSWNLREMLAHAEETRKLMPICMDVRAIMATIQRKYKGIKIQEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHGFNLEEAARCMRSLKAPAVVSVSSPDAVTTYNGYLTSSSKTSEEHFVETVSLAGSYRDWSYSGQRTELGVEFLKRGDKIVYHTLESPVEFHLDGEVLSLDKLKSLLSLREVKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVTDVFYKETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDLVPTQPLPNASFDNFKLTCSNTKFADDLNQMTGFTKPASRELSVTFFPDLNGDVVAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQGMDNLACESQQPTSEEVVENPTIQKEVIECDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAAYVENTSITIKKPNELSLALGLKTIATHGIAAINSVPWSKILAYVKPFLGQAAITTSNCAKRLAQRVFNNYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVKSPKFSKLFTIAMWLLLLSICLGSLICVTAAFGVLLSNFGAPSYCNGVRELYLNSSNVTTMDFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYKLDLTILGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESASKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYIVMPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGGSYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNEKVAGFAKFLKTNCCRFQEKDEEGNLLDSYFVVKRHTMSNYQHEETIYNLVKDCPAVAVHDFFKFRVDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQSLLKTVQFCDAMRDAGIVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSLLMPILTLTRALAAESHMDADLAKPLIKWDLLKYDFTEERLCLFDRYFKYWDQTYHPNCINCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWDYPKCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHLSVDIKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATRDAVGTNLPLQLGFSTGVNLVAVPTGYVDTENNTEFTRVNAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDKRATCFSTSSDTYACWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWSVEYPIIGDELRVNSACRKVQHMVVKSALLADKFPVLHDIGNPKAIKCVPQAEVEWKFYDAQPCSDKAYKIEELFYSYATHHDKFTDGVCLFWNCNVDRYPANAIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFTNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQFDTYNLWNTFTRLQSLENVAYNVVNKGHFDGHAGEAPVSIINNAVYTKVDGIDVEIFENKTTLPVNVAFELWAKRNIKPVPEIKILNNLGVDIAANTVIWDYKREAPAHVSTIGVCTMTDIAKKPTESACSSLTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQASVNGVTLIGESVKTQFNYFKKVDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYGDFSHGQLGGLHLMIGLAKRSQDSPLKLEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQAWQPGVAMPNLYKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPRTKHVTKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWNADLYKLMGHFSWWTAFVTNVNASSSEAFLIGANYLGKPKEQIDGYTMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDILVNN", "length": 7073, "reference_go_mf": ["GO:0000175", "GO:0032574", "GO:0034062", "GO:0005524", "GO:0016887", "GO:0004843", "GO:0004197", "GO:0003678", "GO:0004519", "GO:0002151", "GO:0042802", "GO:1990380", "GO:0061578", "GO:0016829", "GO:0004483", "GO:0004482", "GO:0004484", "GO:0008242", "GO:0003968", "GO:0003727", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_832_1de3_assembly1", "enzyme_name": "rRNA endonuclease", "ec": ["3.1.27.10"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00655", "alignment_score": 300.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [27, 177], "sequence": "MVAIKNLVLVALTAVTALAVPSPLEARAVTWTCLNDQKNPKTNKYETKRLLYNQNKAESNSHHAPLSDGKTGSSYPHWFTNGYDGDGKLPKGRTPIKFGKSDCDRPPKHSKDGNGKTDHYLLEFPTFPDGHDYKFDSKKPKENPGPARVIYTYPNKVFCGIIAHTKENQGELKLCSH", "length": 177, "reference_go_mf": ["GO:0003723", "GO:0004521", "GO:0033902"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_be150ed0552519cae112"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_833_1qhg_assembly1", "enzyme_name": "DNA helicase", "ec": ["3.6.4.12"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P56255", "alignment_score": 1207.5, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 651], "sequence": "MNFLSEQLLAHLNKEQQEAVRTTEGPLLIMAGAGSGKTRVLTHRIAYLMAEKHVAPWNILAITFTNKAAREMRERVQSLLGGAAEDVWISTFHSMCVRILRRDIDRIGINRNFSILDPTDQLSVMKTILKEKNIDPKKFEPRTILGTISAAKNELLPPEQFAKRASTYYEKVVSDVYQEYQQRLLRNHSLDFDDLIMTTIQLFDRVPDVLHYYQYKFQYIHIDEYQDTNRAQYTLVKKLAERFQNICAVGDADQSIYRWRGADIQNILSFERDYPNAKVILLEQNYRSTKRILQAANEVIEHNVNRKPKRIWTENPEGKPILYYEAMNEADEAQFVAGRIREAVERGERRYRDFAVLYRTNAQSRVMEEMLLKANIPYQIVGGLKFYDRKEIKDILAYLRVIANPDDDLSLLRIINVPKRGIGASTIDKLVRYAADHELSLFEALGELEMIGLGAKAAGALAAFRSQLEQWTQLQEYVSVTELVEEVLDKSGYREMLKAERTIEAQSRLENLDEFLSVTKHFENVSDDKSLIAFLTDLALISDLDELDGTEQAAEGDAVMLMTLHAAKGLEFPVVFLIGMEEGIFPHNRSLEDDDEMEEERRLAYVGITRAEEELVLTSAQMRTLFGNIQMDPPSRFLNEIPAHLLETASRRQAGASRPAVSRPQASGAVGSWKVGDRANHRKWGIGTVVSVRGGGDDQELDIAFPSPIGIKRLLAKFAPIEKV", "length": 724, "reference_go_mf": ["GO:0043138", "GO:0005524", "GO:0016887", "GO:0003677"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_a219069e9887f1d9b82d"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_835_1euu_assembly1", "enzyme_name": "exo-alpha-sialidase (GH33 Family)", "ec": ["3.2.1.18"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q02834", "alignment_score": 1202.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [46, 647], "sequence": "MTANPYLRRLPRRRAVSFLLAPALAAATVAGASPAQAIAGAPVPPGGEPLYTEQDLAVNGREGFPNYRIPALTVTPDGDLLASYDGRPTGIDAPGPNSILQRRSTDGGRTWGEQQVVSAGQTTAPIKGFSDPSYLVDRETGTIFNFHVYSQRQGFAGSRPGTDPADPNVLHANVATSTDGGLTWSHRTITADITPDPGWRSRFAASGEGIQLRYGPHAGRLIQQYTIINAAGAFQAVSVYSDDHGRTWRAGEAVGVGMDENKTVELSDGRVLLNSRDSARSGYRKVAVSTDGGHSYGPVTIDRDLPDPTNNASIIRAFPDAPAGSARAKVLLFSNAASQTSRSQGTIRMSCDDGQTWPVSKVFQPGSMSYSTLTALPDGTYGLLYEPGTGIRYANFNLAWLGGICAPFTIPDVALEPGQQVTVPVAVTNQSGIAVPKPSLQLDASPDWQVQGSVEPLMPGRQAKGQVTITVPAGTTPGRYRVGATLRTSAGNASTTFTVTVGLLDQARMSIADVDSEETAREDGRASNVIDGNPSTFWHTEWSRADAPGYPHRISLDLGGTHTISGLQYTRRQNSANEQVADYEIYTSLNGTTWDGPVASGRFTTSLAPQRAVFPARDARYIRLVALSEQTGHKYAAVAELEVEGQR", "length": 647, "reference_go_mf": ["GO:0004308"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_9342ac5006e406c8d3f3"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_836_1avq_assembly1", "enzyme_name": "exodeoxyribonuclease (lambda-induced)", "ec": ["3.1.11.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P03697", "alignment_score": 452.0, "observed_coverage": 0.9912280701754386, "aligned_identity": 1.0, "canonical_span": [0, 226], "sequence": "MTPDIILQRTGIDVRAVEQGDDAWHKLRLGVITASEVHNVIAKPRSGKKWPDMKMSYFHTLLAEVCTGVAPEVNAKALAWGKQYENDARTLFEFTSGVNVTESPIIYRDESMRTACSPDGLCSDGNGLELKCPFTSRDFMKFRLGGFEAIKSAYMAQVQYSMWVTRKNAWYFANYDPRMKREGLHYVVIERDEKYMASFDEIVPEFIEKMDEALAEIGFVFGEQWR", "length": 226, "reference_go_mf": ["GO:0051908", "GO:0046872"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_46daea7aa61dfb1b2403"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_837_1cz0_assembly1", "enzyme_name": "intron-encoded endonuclease I-PpoI", "ec": ["3.1.-.-"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q94702", "alignment_score": 324.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 163], "sequence": "MALTNAQILAVIDSWEETVGQFPVITHHVPLGGGLQGTLHCYEIPLAAPYGVGFAKNGPTRWQYKRTINQVVHRWGSHTVPFLLEPDNINGKTCTASHLCHNTRCHNPLHLCWESLDDNKGRNWCPGPNGGCVHAVVCLRQGPLYGPGATVAGPQQRGSHFVV", "length": 163, "reference_go_mf": ["GO:0004519"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_e0980af198d4d2a15221"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_839_1cw0_assembly1", "enzyme_name": "very short patch repair endonuclease", "ec": ["3.1.-.-"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P09184", "alignment_score": 310.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 156], "sequence": "MADVHDKATRSKNMRAIATRDTAIEKRLASLLTGQGLAFRVQDASLPGRPDFVVDEYRCVIFTHGCFWHHHHCYLFKVPATRTEFWLEKIGKNVERDRRDISRLQELGWRVLIVWECALRGREKLTDEALTERLEEWICGEGASAQIDTQGIHLLA", "length": 156, "reference_go_mf": ["GO:0003677", "GO:0043765"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_6696f86b40bfe7a10f05"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_83_1l8s_assembly1", "enzyme_name": "phospholipase A2 (group IB)", "ec": ["3.1.1.4"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00592", "alignment_score": 248.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [22, 146], "sequence": "MKFLVLAVLLTVGAAQEGISSRALWQFRSMIKCAIPGSHPLMDFNNYGCYCGLGGSGTPVDELDRCCETHDNCYRDAKNLDSCKFLVDNPYTESYSYSCSNTEITCNSKNNACEAFICNCDRNAAICFSKAPYNKEHKNLDTKKYC", "length": 146, "reference_go_mf": ["GO:0004623", "GO:0032052", "GO:0005509", "GO:0005543", "GO:0005102"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_c07db705bbd0685cb620"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_840_1ro7_assembly1", "enzyme_name": "alpha-2,3-sialyltransferase", "ec": ["2.4.99.-"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q9LAK3", "alignment_score": 495.0, "observed_coverage": 1.0, "aligned_identity": 0.996078431372549, "canonical_span": [1, 258], "sequence": "MKKVIIAGNGPSLKEIDYSRLPNDFDVFRCNQFYFEDKYYLGKKCKAVFYNPILFFEQYYTLKHLIQNQEYETELIMCSNYNQAHLENENFVKTFYDYFPDAHLGYDFFKQLKDFNAYFKFHEIYFNQRITSGVYMCAVAIALGYKEIYLSGIDFYQNGSSYAFDTKQKNLLKLAPNFKNDNSHYIGHSKNTDIKALEFLEKTYKIKLYCLCPNSLLANFIELAPNLNSNFIIQEKNNYTKDILIPSSEAYGKFSKNINFKKIKIKENIYYKLIKDLLRLPSDIKHYFKGK", "length": 291, "reference_go_mf": [], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_94987931be42a677b6b8"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_841_1pnl_assembly1", "enzyme_name": "penicillin amidase (peptidase S45 family)", "ec": ["3.5.1.11"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P06875", "alignment_score": 1114.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [289, 846], "sequence": "MKNRNRMIVNCVTASLMYYWSLPALAEQSSSEIKIVRDEYGMPHIYANDTWHLFYGYGYVVAQDRLFQMEMARRSTQGTVAEVLGKDFVKFDKDIRRNYWPDAIRAQIAALSPEDMSILQGYADGMNAWIDKVNTNPETLLPKQFNTFGFTPKRWEPFDVAMIFVGTMANRFSDSTSEIDNLALLTALKDKYGVSQGMAVFNQLKWLVNPSAPTTIAVQESNYPLKFNQQNSQTAALLPRYDLPAPMLDRPAKGADGALLALTAGKNRETIAAQFAQGGANGLAGYPTTSNMWVIGKSKAQDAKAIMVNGPQFGWYAPAYTYGIGLHGAGYDVTGNTPFAYPGLVFGHNGVISWGSTAGFGDDVDIFAERLSAEKPGYYLHNGKWVKMLSREETITVKNGQAETFTVWRTVHGNILQTDQTTQTAYAKSRAWDGKEVASLLAWTHQMKAKNWQEWTQQAAKQALTINWYYADVNGNIGYVHTGAYPDRQSGHDPRLPVPGTGKWDWKGLLPFEMNPKVYNPQSGYIANWNNSPQKDYPASDLFAFLWGGADRVTEIDRLLEQKPRLTADQAWDVIRQTSRQDLNLRLFLPTLQAATSGLTQSDPRRQLVETLTRWDGINLLNDDGKTWQQPGSAILNVWLTSMLKRTVVAAVPMPFDKWYSASGYETTQDGPTGSLNISVGAKILYEAVQGDKSPIPQAVDLFAGKPQQEVVLAALEDTWETLSKRYGNNVSNWKTPAMALTFRANNFFGVPQAAAEETRHQAEYQNRGTENDMIVFSPTTSDRPVLAWDVVAPGQSGFIAPDGTVDKHYEDQLKMYENFGRKSLWLTKQDVEAHKESQEVLHVQR", "length": 846, "reference_go_mf": ["GO:0008953"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_6d9a89240324c9f4695b"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_842_1dqr_assembly1", "enzyme_name": "glucose-6-phosphate isomerase", "ec": ["5.3.1.9"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q9N1E2", "alignment_score": 1107.0, "observed_coverage": 1.0, "aligned_identity": 0.9981981981981982, "canonical_span": [1, 556], "sequence": "MAALTRNPQFQKLQQWHREHGSELNLRHLFDTDKERFNHFSLTLNTNHGHILLDYSKNLVTEEVMHMLLDLAKSRGVEAARESMFNGEKINSTEDRAVLHVALRNRSNTPIVVDGKDVMPEVNKVLDKMKAFCQRVRSGDWKGYTGKTITDVINIGIGGSDLGPLMVTEALKPYSSGGPRVWFVSNIDGTHIAKTLACLNPESSLFIIASKTFTTQETITNAETAKDWFLLSAKDPSTVAKHFVALSTNTAKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQLLSGAHWMDQHFRTTPLEKNAPVLLAMLGIWYINCFGCETQAVLPYDQYLHRFAAYFQQGDMESNGKYITKSGARVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPIRKGLHHKILLANFLAQTEALMKGKSTEEARKELQAAGKSPEDLMKLLPHKVFEGNRPTNSIVFTKLTPFILGALIAMYEHKIFVQGVVWDINSFDQWGVELGKQLAKKIEPELDGSSPVTSHDSSTNGLINFIKQQREAKIQ", "length": 558, "reference_go_mf": ["GO:0097367", "GO:0047938", "GO:0004347", "GO:0048029", "GO:0016857"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_239a5fdadffd8b5096c7"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "Q9N1E2", "alignment_score": 1107.0, "observed_coverage": 1.0, "aligned_identity": 0.9981981981981982, "canonical_span": [1, 556], "sequence": "MAALTRNPQFQKLQQWHREHGSELNLRHLFDTDKERFNHFSLTLNTNHGHILLDYSKNLVTEEVMHMLLDLAKSRGVEAARESMFNGEKINSTEDRAVLHVALRNRSNTPIVVDGKDVMPEVNKVLDKMKAFCQRVRSGDWKGYTGKTITDVINIGIGGSDLGPLMVTEALKPYSSGGPRVWFVSNIDGTHIAKTLACLNPESSLFIIASKTFTTQETITNAETAKDWFLLSAKDPSTVAKHFVALSTNTAKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQLLSGAHWMDQHFRTTPLEKNAPVLLAMLGIWYINCFGCETQAVLPYDQYLHRFAAYFQQGDMESNGKYITKSGARVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPIRKGLHHKILLANFLAQTEALMKGKSTEEARKELQAAGKSPEDLMKLLPHKVFEGNRPTNSIVFTKLTPFILGALIAMYEHKIFVQGVVWDINSFDQWGVELGKQLAKKIEPELDGSSPVTSHDSSTNGLINFIKQQREAKIQ", "length": 558, "reference_go_mf": ["GO:0097367", "GO:0047938", "GO:0004347", "GO:0048029", "GO:0016857"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_239a5fdadffd8b5096c7"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_843_1dpg_assembly1", "enzyme_name": "glucose-6-phosphate dehydrogenase", "ec": ["1.1.1.49"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P11411", "alignment_score": 967.0, "observed_coverage": 1.0, "aligned_identity": 0.9979381443298969, "canonical_span": [1, 486], "sequence": "MVSEIKTLVTFFGGTGDLAKRKLYPSVFNLYKKGYLQKHFAIVGTARQALNDDEFKQLVRDSIKDFTDDQAQAEAFIEHFSYRAHDVTDAASYAVLKEAIEEAADKFDIDGNRIFYMSVAPRFFGTIAKYLKSEGLLADTGYNRLMIEKPFGTSYDTAAELQNDLENAFDDNQLFRIDHYLGKEMVQNIAALRFGNPIFDAAWNKDYIKNVQVTLSEVLGVEERAGYYDTAGALLDMIQNHTMQIVGWLAMEKPESFTDKDIRAAKNAAFNALKIYDEAEVNKYFVRAQYGAGDSADFKPYLEELDVPADSKNNTFIAGELQFDLPRWEGVPFYVRSGKRLAAKQTRVDIVFKAGTFNFGSEQEAQEAVLSIIIDPKGAIELKLNAKSVEDAFNTRTIDLGWTVSDEDKKNTPEPYERMIHDTMNGDGSNFADWNGVSIAWKFVDAISAVYTADKAPLETYKSGSMGPEASDKLLAANGDAWVFKG", "length": 486, "reference_go_mf": ["GO:0004345", "GO:0050661"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_ca12606c68c0ecf0c21c"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_844_1dup_assembly1", "enzyme_name": "dUTP diphosphatase", "ec": ["3.6.1.23"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P06968", "alignment_score": 272.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 136], "sequence": "MMKKIDVKILDPRVGKEFPLPTYATSGSAGLDLRACLNDAVELAPGDTTLVPTGLAIHIADPSLAAMMLPRSGLGHKHGIVLGNLVGLIDSDYQGQLMISVWNRGQDSFTIQPGERIAQMIFVPVVQAEFNLVEDFDATDRGEGGFGHSGRQ", "length": 152, "reference_go_mf": ["GO:0004170", "GO:0042802", "GO:0000287"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_1b3163146aa909051628"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P06968", "alignment_score": 272.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 136], "sequence": "MMKKIDVKILDPRVGKEFPLPTYATSGSAGLDLRACLNDAVELAPGDTTLVPTGLAIHIADPSLAAMMLPRSGLGHKHGIVLGNLVGLIDSDYQGQLMISVWNRGQDSFTIQPGERIAQMIFVPVVQAEFNLVEDFDATDRGEGGFGHSGRQ", "length": 152, "reference_go_mf": ["GO:0004170", "GO:0042802", "GO:0000287"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_1b3163146aa909051628"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_845_1dw9_assembly1", "enzyme_name": "cyanase", "ec": ["4.2.1.104"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00816", "alignment_score": 286.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 156], "sequence": "MIQSQINRNIRLDLADAILLSKAKKDLSFAEIADGTGLAEAFVTAALLGQQALPADAARLVGAKLDLDEDSILLLQMIPLRGCIDDRIPTDPTMYRFYEMLQVYGTTLKALVHEKFGDGIISAINFKLDVKKVADPEGGERAVITLDGKYLPTKPF", "length": 156, "reference_go_mf": ["GO:0008824", "GO:0003677"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_947527cb44ad345f9a1c"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P00816", "alignment_score": 286.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 156], "sequence": "MIQSQINRNIRLDLADAILLSKAKKDLSFAEIADGTGLAEAFVTAALLGQQALPADAARLVGAKLDLDEDSILLLQMIPLRGCIDDRIPTDPTMYRFYEMLQVYGTTLKALVHEKFGDGIISAINFKLDVKKVADPEGGERAVITLDGKYLPTKPF", "length": 156, "reference_go_mf": ["GO:0008824", "GO:0003677"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_947527cb44ad345f9a1c"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_846_1dxe_assembly1", "enzyme_name": "2-dehydro-3-deoxyglucarate aldolase", "ec": ["4.1.2.20"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P23522", "alignment_score": 506.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [3, 256], "sequence": "MNNDVFPNKFKAALAAKQVQIGCWSALSNPISTEVLGLAGFDWLVLDGEHAPNDISTFIPQLMALKGSASAPVVRVPTNEPVIIKRLLDIGFYNFLIPFVETKEEAELAVASTRYPPEGIRGVSVSHRANMFGTVADYFAQSNKNITILVQIESQQGVDNVDAIAATEGVDGIFVGPSDLAAALGHLGNASHPDVQKAIQHIFNRASAHGKPSGILAPVEADARRYLEWGATFVAVGSDLGVFRSATQKLADTFKK", "length": 256, "reference_go_mf": ["GO:0061677", "GO:0008672", "GO:0016832", "GO:0016830", "GO:0000287"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_7be9bc1e78d4269b66c6"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P23522", "alignment_score": 506.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [3, 256], "sequence": "MNNDVFPNKFKAALAAKQVQIGCWSALSNPISTEVLGLAGFDWLVLDGEHAPNDISTFIPQLMALKGSASAPVVRVPTNEPVIIKRLLDIGFYNFLIPFVETKEEAELAVASTRYPPEGIRGVSVSHRANMFGTVADYFAQSNKNITILVQIESQQGVDNVDAIAATEGVDGIFVGPSDLAAALGHLGNASHPDVQKAIQHIFNRASAHGKPSGILAPVEADARRYLEWGATFVAVGSDLGVFRSATQKLADTFKK", "length": 256, "reference_go_mf": ["GO:0061677", "GO:0008672", "GO:0016832", "GO:0016830", "GO:0000287"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_7be9bc1e78d4269b66c6"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_847_1ehy_assembly1", "enzyme_name": "epoxide hydrolase", "ec": ["3.3.2.10"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "O31243", "alignment_score": 551.0, "observed_coverage": 0.9964539007092199, "aligned_identity": 1.0, "canonical_span": [2, 294], "sequence": "MTIRRPEDFKHYEVQLPDVKIHYVREGAGPTLLLLHGWPGFWWEWSKVIGPLAEHYDVIVPDLRGFGDSEKPDLNDLSKYSLDKAADDQAALLDALGIEKAYVVGHDFAAIVLHKFIRKYSDRVIKAAIFDPIQPDFGPVYFGLGHVHESWYSQFHQLDMAVEVVGSSREVCKKYFKHFFDHWSYRDELLTEEELEVHVDNCMKPDNIHGGFNYYRANIRPDAALWTDLDHTMSDLPVTMIWGLGDTCVPYAPLIEFVPKYYSNYTMETIEDCGHFLMVEKPEIAIDRIKTAFR", "length": 294, "reference_go_mf": ["GO:0016787"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_233a6617eeb739277330"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_848_1elu_assembly1", "enzyme_name": "L-cysteine/cystine lyase", "ec": ["4.4.1.35"], "controls": [{"chain": "A", "status": "missing_reference", "selected": null, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_849_1su4_assembly1", "enzyme_name": "Ca(II)-transporting ATPase", "ec": ["7.2.2.10"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P04191", "alignment_score": 1986.0, "observed_coverage": 0.9989939637826962, "aligned_identity": 1.0, "canonical_span": [0, 993], "sequence": "MEAAHSKSTEECLAYFGVSETTGLTPDQVKRHLEKYGHNELPAEEGKSLWELVIEQFEDLLVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKEYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILSIKSTTLRVDQSILTGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVSTEIGKIRDQMAATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWIRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCKMFIIDKVDGDFCSLNEFSITGSTYAPEGEVLKNDKPIRSGQFDGLVELATICALCNDSSLDFNETKGVYEKVGEATETALTTLVEKMNVFNTEVRNLSKVERANACNSVIRQLMKKEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPMTGPVKEKILSVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSSRFMEYETDLTFVGVVGMLDPPRKEVMGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDDLPLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAIGGYVGAATVGAAAWWFMYAEDGPGVTYHQLTHFMQCTEDHPHFEGLDCEIFEAPEPMTMALSVLVTIEMCNALNSLSENQSLMRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLKALDLTQWLMVLKISLPVIGLDEILKFIARNYLEDPEDERRK", "length": 1001, "reference_go_mf": ["GO:0005524", "GO:0016887", "GO:0005509", "GO:0005388"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_a168ed112da6077bf160"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_84_1b66_assembly1", "enzyme_name": "6-pyruvoyltetrahydropterin synthase", "ec": ["4.2.3.12"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P27213", "alignment_score": 276.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [6, 144], "sequence": "MNAAVGLRRRARLSRLVSFSASHRLHSPSLSAEENLKVFGKCNNPNGHGHNYKVVVTIHGEIDPVTGMVMNLTDLKEYMEEAIMKPLDHKNLDLDVPYFADVVSTTENVAVYIWENLQRLLPVGALYKVKVYETDNNIVVYKGE", "length": 144, "reference_go_mf": ["GO:0003874", "GO:0042802"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_69993b2b2054d91bc6a7"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P27213", "alignment_score": 276.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [6, 144], "sequence": "MNAAVGLRRRARLSRLVSFSASHRLHSPSLSAEENLKVFGKCNNPNGHGHNYKVVVTIHGEIDPVTGMVMNLTDLKEYMEEAIMKPLDHKNLDLDVPYFADVVSTTENVAVYIWENLQRLLPVGALYKVKVYETDNNIVVYKGE", "length": 144, "reference_go_mf": ["GO:0003874", "GO:0042802"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_69993b2b2054d91bc6a7"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_850_1euy_assembly1", "enzyme_name": "glutamine---tRNA ligase", "ec": ["6.1.1.18"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00962", "alignment_score": 1047.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [8, 548], "sequence": "MSEAEARPTNFIRQIIDEDLASGKHTTVHTRFPPEPNGYLHIGHAKSICLNFGIAQDYKGQCNLRFDDTNPVKEDIEYVESIKNDVEWLGFHWSGNVRYSSDYFDQLHAYAIELINKGLAYVDELTPEQIREYRGTLTQPGKNSPYRDRSVEENLALFEKMRAGGFEEGKACLRAKIDMASPFIVMRDPVLYRIKFAEHHQTGNKWCIYPMYDFTHCISDALEGITHSLCTLEFQDNRRLYDWVLDNITIPVHPRQYEFSRLNLEYTVMSKRKLNLLVTDKHVEGWDDPRMPTISGLRRRGYTAASIREFCKRIGVTKQDNTIEMASLESCIREDLNENAPRAMAVIDPVKLVIENYQGEGEMVTMPNHPNKPEMGSRQVPFSGEIWIDRADFREEANKQYKRLVLGKEVRLRNAYVIKAERVEKDAEGNITTIFCTYDADTLSKDPADGRKVKGVIHWVSAAHALPVEIRLYDRLFSVPNPGAADDFLSVINPESLVIKQGFAEPSLKDAVAGKAFQFEREGYFCLDSRHSTAEKPVFNRTVGLRDTWAKVGE", "length": 554, "reference_go_mf": ["GO:0005524", "GO:0004819"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_8e6aba94bc4bc19b1884"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_852_1gox_assembly1", "enzyme_name": "(S)-2-hydroxy-acid oxidase", "ec": ["1.1.3.15"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P05414", "alignment_score": 690.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 359], "sequence": "MEITNVNEYEAIAKQKLPKMVYDYYASGAEDQWTLAENRNAFSRILFRPRILIDVTNIDMTTTILGFKISMPIMIAPTAMQKMAHPEGEYATARAASAAGTIMTLSSWATSSVEEVASTGPGIRFFQLYVYKDRNVVAQLVRRAERAGFKAIALTVDTPRLGRREADIKNRFVLPPFLTLKNFEGIDLGKMDKANDSGLSSYVAGQIDRSLSWKDVAWLQTITSLPILVKGVITAEDARLAVQHGAAGIIVSNHGARQLDYVPATIMALEEVVKAAQGRIPVFLDGGVRRGTDVFKALALGAAGVFIGRPVVFSLAAEGEAGVKKVLQMMRDEFELTMALSGCRSLKEISRSHIAADWDGPSSRAVARL", "length": 369, "reference_go_mf": ["GO:0003973", "GO:0047639", "GO:0010181"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_0b0b47f584fae218abf6"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_853_1g64_assembly1", "enzyme_name": "cob(I)yrinic acid a,c-diamide adenosyltransferase", "ec": ["2.5.1.17"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P31570", "alignment_score": 338.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [27, 196], "sequence": "MSDERYQQRQQKVKDRVDARVAQAQEERGIIIVFTGNGKGKTTAAFGTAARAVGHGKNVGVVQFIKGTWPNGERNLLEPHGVEFQVMATGFTWETQNREADTAACMAVWQHGKRMLADPLLDMVVLDELTYMVAYDYLPLEEVISALNARPGHQTVIITGRGCHRDILDLADTVSELRPVKHAFDAGVKAQMGIDY", "length": 196, "reference_go_mf": ["GO:0005524", "GO:0008817"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_da33717e591e9e86f50c"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P31570", "alignment_score": 380.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [6, 196], "sequence": "MSDERYQQRQQKVKDRVDARVAQAQEERGIIIVFTGNGKGKTTAAFGTAARAVGHGKNVGVVQFIKGTWPNGERNLLEPHGVEFQVMATGFTWETQNREADTAACMAVWQHGKRMLADPLLDMVVLDELTYMVAYDYLPLEEVISALNARPGHQTVIITGRGCHRDILDLADTVSELRPVKHAFDAGVKAQMGIDY", "length": 196, "reference_go_mf": ["GO:0005524", "GO:0008817"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_da33717e591e9e86f50c"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_854_1ohv_assembly1", "enzyme_name": "4-aminobutyrate transaminase", "ec": ["2.6.1.19"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P80147", "alignment_score": 922.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [38, 499], "sequence": "MASVLLTRRLACSFRHNHRLLVPGWRHISQAAAKVDVEFDYDGPLMKTEVPGPRSRELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSIPIGYSHPALVKLVQQPQNVSTFINRPALGILPPENFVEKLRESLLSVAPKGMSQLITMACGSCSNENAFKTIFMWYRSKERGQSAFSKEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDISRKHGCAFLVDEVQTGGGSTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLSNAAHAGKVLLTGLLDLQARYPQFISRVRGRGTFCSFDTPDESIRNKLISIARNKGVMLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK", "length": 500, "reference_go_mf": ["GO:0047298", "GO:0034386", "GO:0042803", "GO:0030170", "GO:0032145"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_a29ccaa70b908203a9dc"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P80147", "alignment_score": 922.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [38, 499], "sequence": "MASVLLTRRLACSFRHNHRLLVPGWRHISQAAAKVDVEFDYDGPLMKTEVPGPRSRELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSIPIGYSHPALVKLVQQPQNVSTFINRPALGILPPENFVEKLRESLLSVAPKGMSQLITMACGSCSNENAFKTIFMWYRSKERGQSAFSKEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDISRKHGCAFLVDEVQTGGGSTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLSNAAHAGKVLLTGLLDLQARYPQFISRVRGRGTFCSFDTPDESIRNKLISIARNKGVMLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK", "length": 500, "reference_go_mf": ["GO:0047298", "GO:0034386", "GO:0042803", "GO:0030170", "GO:0032145"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_a29ccaa70b908203a9dc"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_855_1i29_assembly1", "enzyme_name": "cysteine desulfurase", "ec": ["2.8.1.7"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P77444", "alignment_score": 810.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 406], "sequence": "MIFSVDKVRADFPVLSREVNGLPLAYLDSAASAQKPSQVIDAEAEFYRHGYAAVHRGIHTLSAQATEKMENVRKRASLFINARSAEELVFVRGTTEGINLVANSWGNSNVRAGDNIIISQMEHHANIVPWQMLCARVGAELRVIPLNPDGTLQLETLPTLFDEKTRLLAITHVSNVLGTENPLAEMITLAHQHGAKVLVDGAQAVMHHPVDVQALDCDFYVFSGHKLYGPTGIGILYVKEALLQEMPPWEGGGSMIATVSLSEGTTWTKAPWRFEAGTPNTGGIIGLGAALEYVSALGLNNIAEYEQNLMHYALSQLESVPDLTLYGPQNRLGVIAFNLGKHHAYDVGSFLDNYGIAVRTGHHCAMPLMAYYNVPAMCRASLAMYNTHEEVDRLVTGLQRIHRLLG", "length": 406, "reference_go_mf": ["GO:0031071", "GO:0008826", "GO:0042803", "GO:0030170", "GO:0009000"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_55567a3085f9073ebfe3"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_856_1inp_assembly1", "enzyme_name": "inositol-1,4-bisphosphate 1-phosphatase", "ec": ["3.1.3.57"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P21327", "alignment_score": 797.0, "observed_coverage": 1.0, "aligned_identity": 0.9975, "canonical_span": [0, 400], "sequence": "MSDILQELLRVSEKAANIARACRQQETLFQLLIEEKKEGEKNKKFAVDFKTLADVLVQEVIKENMENKFPGLGKKIFGEESNEFTNDLGEKIIMRLGPTEEETVALLSKVLNGNKLASEALAKVVHQDVFFSDPALDSVEINIPQDILGIWVDPIDSTYQYIKGSADITPNQGIFPSGLQCVTVLIGVYDIQTGVPLMGVINQPFVSQDLHTRRWKGQCYWGLSYLGTNIHSLLPPVSTRSNSEAQSQGTQNPSSEGSCRFSVVISTSEKETIKGALSHVCGERIFRAAGAGYKSLCVILGLADIYIFSEDTTFKWDSCAAHAILRAMGGGMVDLKECLERNPDTGLDLPQLVYHVGNEGAAGVDQWANKGGLIAYRSEKQLETFLSRLLQHLAPVATHT", "length": 400, "reference_go_mf": ["GO:0052829", "GO:0004441"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_f0c80a6f95d3fbb90f5a"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_857_1qb4_assembly1", "enzyme_name": "phosphoenolpyruvate carboxylase", "ec": ["4.1.1.31"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00864", "alignment_score": 1737.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [3, 883], "sequence": "MNEQYSALRSNVSMLGKVLGETIKDALGEHILERVETIRKLSKSSRAGNDANRQELLTTLQNLSNDELLPVARAFSQFLNLANTAEQYHSISPKGEAASNPEVIARTLRKLKNQPELSEDTIKKAVESLSLELVLTAHPTEITRRTLIHKMVEVNACLKQLDNKDIADYEHNQLMRRLRQLIAQSWHTDEIRKLRPSPVDEAKWGFAVVENSLWQGVPNYLRELNEQLEENLGYKLPVEFVPVRFTSWMGGDRDGNPNVTADITRHVLLLSRWKATDLFLKDIQVLVSELSMVEATPELLALVGEEGAAEPYRYLMKNLRSRLMATQAWLEARLKGEELPKPEGLLTQNEELWEPLYACYQSLQACGMGIIANGDLLDTLRRVKCFGVPLVRIDIRQESTRHTEALGELTRYLGIGDYESWSEADKQAFLIRELNSKRPLLPRNWQPSAETREVLDTCQVIAEAPQGSIAAYVISMAKTPSDVLAVHLLLKEAGIGFAMPVAPLFETLDDLNNANDVMTQLLNIDWYRGLIQGKQMVMIGYSDSAKDAGVMAASWAQYQAQDALIKTCEKAGIELTLFHGRGGSIGRGGAPAHAALLSQPPGSLKGGLRVTEQGEMIRFKYGLPEITVSSLSLYTGAILEANLLPPPEPKESWRRIMDELSVISCDVYRGYVRENKDFVPYFRSATPEQELGKLPLGSRPAKRRPTGGVESLRAIPWIFAWTQNRLMLPAWLGAGTALQKVVEDGKQSELEAMCRDWPFFSTRLGMLEMVFAKADLWLAEYYDQRLVDKALWPLGKELRNLQEEDIKVVLAIANDSHLMADLPWIAESIQLRNIYTDPLNVLQAELLHRSRQAEKEGQEPDPRVEQALMVTIAGIAAGMRNTG", "length": 883, "reference_go_mf": ["GO:0042802", "GO:0000287", "GO:0008964"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_12bf79701f86653a217d"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_858_1mrq_assembly1", "enzyme_name": "indanol dehydrogenase", "ec": ["1.1.1.112"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q04828", "alignment_score": 644.0, "observed_coverage": 0.9969040247678018, "aligned_identity": 1.0, "canonical_span": [1, 323], "sequence": "MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY", "length": 323, "reference_go_mf": ["GO:0047006", "GO:0044594", "GO:0072582", "GO:0140169", "GO:0033703", "GO:0000253", "GO:0047024", "GO:0008106", "GO:0004032", "GO:0047044", "GO:0047023", "GO:0032052", "GO:0004090", "GO:0031406", "GO:0004303", "GO:0047718", "GO:0047086", "GO:0016655", "GO:0033764", "GO:0047045", "GO:0047115"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_4a269c619d2ffc03cca3"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_859_1nf9_assembly1", "enzyme_name": "isochorismatase", "ec": ["3.3.2.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0DPB9", "alignment_score": 414.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 207], "sequence": "MSGIPEITAYPLPTAQQLPANLARWSLEPRRAVLLVHDMQRYFLRPLPESLRAGLVANAARLRRWCVEQGVQIAYTAQPGSMTEEQRGLLKDFWGPGMRASPADREVVEELAPGPDDWLLTKWRYSAFFHSDLLQRMRAAGRDQLVLCGVYAHVGVLISTVDAYSNDIQPFLVADAIADFSEAHHRMALEYAASRCAMVVTTDEVLE", "length": 207, "reference_go_mf": ["GO:0008908"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_d35d5ae25473eecfd0dd"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_85_1b93_assembly1", "enzyme_name": "methylglyoxal synthase", "ec": ["4.2.3.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0A731", "alignment_score": 296.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 148], "sequence": "MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPHFNDAVDILIPDYQRYLADRLK", "length": 152, "reference_go_mf": ["GO:0042802", "GO:0008929"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_2589b49949bea3833dd1"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P0A731", "alignment_score": 288.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 144], "sequence": "MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPHFNDAVDILIPDYQRYLADRLK", "length": 152, "reference_go_mf": ["GO:0042802", "GO:0008929"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_2589b49949bea3833dd1"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_860_1ord_assembly1", "enzyme_name": "ornithine decarboxylase", "ec": ["4.1.1.17"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P43099", "alignment_score": 1460.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 731], "sequence": "MSSSLKIASTQEARQYFDTDRVVVDAVGSDFTDVGAVIAMDYETDVIDAADATKFGIPVFAVTKDAQAISADELKKIFHIIDLENKFDATVNAREIETAVNNYEDSILPPFFKSLKEYVSRGLIQFDCPGHQGGQYYRKHPAGREFYDFFGETVFRADLCNADVALGDLLIHEGPAVAAEKHAARVYNADKTYFVLGGSSNANNTVTSALVSNGDLVLFDRNNHKSVYNSALAMAGGRPVYLQTNRNPYGFIGGIYDSDFDEKKIRELAAKVDPERAKWKRPFRLAVIQLGTYDGTIYNAHEVVKRIGHLCDYIEFDSAWVGYEQFIPMMRNSSPLLIDDLGPEDPGIIVVQSVHKQQAGFSQTSQIHKKDSHIKGQLRYCDHKHFNNSFNLFMSTSPFYPMYAALDVNAAMQEGEAGRKLWHDLLITTIEARKKLIKAGSMFRPFVPPVVNGKKWEDGDTEDMANNIDYWRFEKGAKWHAYEGYGDNQYYVDPNKFMLTTPGINPETGDYEDFGVPATIVANYLRDHGIIPEKSDLNSILFLMTPAETPAKMNNLITQLLQLQRLIEEDAPLKQVLPSIYAANEERYNGYTIRELCQELHDFYKNNNTFTYQKRLFLREFFPEQGMLPYEARQEFIRNHNKLVPLNKIEGEIALEGALPYPPGVFCVAPGEKWSETAVKYFTILQDGINNFPGFAPEIQGVYFKQEGDKVVAYGEVYDAEVAKNDDRYNN", "length": 731, "reference_go_mf": ["GO:0004586", "GO:0030170"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_3c6943a439a60b5a6c42"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_862_1ndh_assembly1", "enzyme_name": "cytochrome-b5 reductase", "ec": ["1.6.2.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P83686", "alignment_score": 540.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [2, 272], "sequence": "STPAITLENPDIKYPLRLIDKEVVNHDTRRFRFALPSPEHILGLPVGQHIYLSARIDGNLVIRPYTPVSSDDDKGFVDLVIKVYFKDTHPKFPAGGKMSQYLESMKIGDTIEFRGPNGLLVYQGKGKFAIRPDKKSSPVIKTVKSVGMIAGGTGITPMLQVIRAIMKDPDDHTVCHLLFANQTEKDILLRPELEELRNEHSARFKLWYTVDRAPEAWDYSQGFVNEEMIRDHLPPPEEEPLVLMCGPPPMIQYACLPNLERVGHPKERCFAF", "length": 272, "reference_go_mf": ["GO:0004128", "GO:0090524", "GO:0071949", "GO:0050660"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_69b71d0890bc625cd5ac"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_863_1nhx_assembly1", "enzyme_name": "phosphoenolpyruvate carboxykinase (GTP)", "ec": ["4.1.1.32"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P35558", "alignment_score": 1188.5, "observed_coverage": 1.0, "aligned_identity": 0.9933884297520661, "canonical_span": [9, 622], "sequence": "MPPQLQNGLNLSAKVVQGSLDSLPQAVREFLENNAELCQPDHIHICDGSEEENGRLLGQMEEEGILRRLKKYDNCWLALTDPRDVARIESKTVIVTQEQRDTVPIPKTGLSQLGRWMSEEDFEKAFNARFPGCMKGRTMYVIPFSMGPLGSPLSKIGIELTDSPYVVASMRIMTRMGTPVLEAVGDGEFVKCLHSVGCPLPLQKPLVNNWPCNPELTLIAHLPDRREIISFGSGYGGNSLLGKKCFALRMASRLAKEEGWLAEHMLILGITNPEGEKKYLAAAFPSACGKTNLAMMNPSLPGWKVECVGDDIAWMKFDAQGHLRAINPENGFFGVAPGTSVKTNPNAIKTIQKNTIFTNVAETSDGGVYWEGIDEPLASGVTITSWKNKEWSSEDGEPCAHPNSRFCTPASQCPIIDAAWESPEGVPIEGIIFGGRRPAGVPLVYEALSWQHGVFVGAAMRSEATAAAEHKGKIIMHDPFAMRPFFGYNFGKYLAHWLSMAQHPAAKLPKIFHVNWFRKDKEGKFLWPGFGENSRVLEWMFNRIDGKASTKLTPIGYIPKEDALNLKGLGHINMMELFSISKEFWEKEVEDIEKYLEDQVNADLPCEIEREILALKQRISQM", "length": 622, "reference_go_mf": ["GO:0031406", "GO:0005525", "GO:0000287", "GO:0030145", "GO:0004613", "GO:0106264"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_6d2f7a7b9f6d82b74c0f"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_866_1l7a_assembly1", "enzyme_name": "cephalosporin-C deacetylase", "ec": ["3.1.1.41"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P94388", "alignment_score": 630.0, "observed_coverage": 1.0, "aligned_identity": 0.9937106918238994, "canonical_span": [0, 318], "sequence": "MQLFDLPLDQLQTYKPEKTAPKDFSEFWKLSLEELAKVQAEPDLQPVDYPADGVKVYRLTYKSFGNARITGWYAVPDKEGPHPAIVKYHGYNASYDGEIHEMVNWALHGYATFGMLVRGQQSSEDTSISPHGHALGWMTKGILDKDTYYYRGVYLDAVRALEVISSFDEVDETRIGVTGGSQGGGLTIAAAALSDIPKAAVADYPYLSNFERAIDVALEQPYLEINSFFRRNGSPETEVQAMKTLSYFDIMNLADRVKVPVLMSIGLIDKVTPPSTVFAAYNHLETKKELKVYRYFGHEYIPAFQTEKLAFFKQHLKG", "length": 318, "reference_go_mf": ["GO:0046555", "GO:0052689", "GO:0047739"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_4cd47ab556d5becda39a"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_869_1og1_assembly1", "enzyme_name": "NAD+---protein-arginine ADP-ribosyltransferase", "ec": ["2.4.2.31"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P20974", "alignment_score": 446.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [23, 246], "sequence": "MPSNICKFFLTWWLIQQVTGLTGPLMLDTAPNAFDDQYEGCVNKMEEKAPLLLQEDFNMNAKLKVAWEEAKKRWNNIKPSRSYPKGFNDFHGTALVAYTGSIAVDFNRAVREFKENPGQFHYKAFHYYLTRALQLLSNGDCHSVYRGTKTRFHYTGAGSVRFGQFTSSSLSKKVAQSQEFFSDHGTLFIIKTCLGVYIKEFSFRPDQEEVLIPGYEVYQKVRTQGYNEIFLDSPKRKKSNYNCLYSSAGARESCVSLFLVVLPSLLVQLLCLAEP", "length": 275, "reference_go_mf": ["GO:0016798", "GO:0003953", "GO:0106274"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_cbf65153211a28ae7dcb"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_86_1bg0_assembly1", "enzyme_name": "arginine kinase", "ec": ["2.7.3.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P51541", "alignment_score": 703.0, "observed_coverage": 1.0, "aligned_identity": 0.9915730337078652, "canonical_span": [1, 357], "sequence": "MVDQATLDKLEAGFKKLQEASDCKSLLKKHLTKDVFDSIKNKKTGMGATLLDVIQSGVENLDSGVGIYAPDAESYRTFGPLFDPIIDDYHGGFKLTDKHPPKEWGDINTLVDLDPGGQFIISTRVRCGRSLQGYPFNPCLTAEQYKEMEEKVSSTLSSMEDELKGTYYPLTGMSKATQQQLIDDHFLFKEGDRFLQTANACRYWPTGRGIFHNDAKTFLVWVNEEDHLRIISMQKGGDLKTVYKRLVTAVDNIESKLPFSHDDRFGFLTFCPTNLGTTMRASVHIQLPKLAKDRKVLEDIASKFNLQVRGTRGEHTESEGGVYDISNKRRLGLTEYQAVREMQDGILEMIKMEKAAA", "length": 357, "reference_go_mf": ["GO:0004054", "GO:0005524"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_88dad94d6ab8edcc8401"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_872_1or8_assembly1", "enzyme_name": "type I protein arginine methyltransferase", "ec": ["2.1.1.319"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q63009", "alignment_score": 626.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [40, 353], "sequence": "MAAAEAANCIMEVSCGQAESSEKPNAEDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLHARDKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHWWENVYGFDMSCIKDVAIKEPLVDVVDPKQLVTNACLIKEVDIYTVKVEDLTFTSPFCLQVKRNDYVHALVAYFNIEFTRCHKRTGFSTSPESPYTHWKQTVFYMEDYLTVKTGEEIFGTIGMRPNAKNNRDLDFTIDLDFKGQLCELSCSTDYRMR", "length": 353, "reference_go_mf": ["GO:0016273", "GO:0019899", "GO:0106080", "GO:0044020", "GO:0042054", "GO:0042802", "GO:0008327", "GO:0008168", "GO:0048273", "GO:0008170", "GO:0008276", "GO:0016274", "GO:0035242", "GO:0035241", "GO:1904047", "GO:0008757", "GO:0030519"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_f146921d34acfee8ab93"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_874_1otg_assembly1", "enzyme_name": "5-carboxymethyl-2-hydroxymuconate Delta-isomerase", "ec": ["5.3.3.10"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q05354", "alignment_score": 247.0, "observed_coverage": 1.0, "aligned_identity": 0.992, "canonical_span": [1, 126], "sequence": "MPHFIVECSDNIREEADLPGLFAKVNPTLAATGIFPLAGIRSRVHWVDTWQMADGQHDYASVHMTLKIGAGRSLESRQQAGEMLFELIKTHFAALMESRLLALSFEIEELHPTLNFKQNNVHALFK", "length": 126, "reference_go_mf": ["GO:0008704"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_a5422fd3151831fbdb80"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_875_1oyg_assembly1", "enzyme_name": "levansucrase", "ec": ["2.4.1.10"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P05655", "alignment_score": 880.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [33, 473], "sequence": "MNIKKFAKQATVLTFTTALLAGGATQAFAKETNQKPYKETYGISHITRHDMLQIPEQQKNEKYQVPEFDSSTIKNISSAKGLDVWDSWPLQNADGTVANYHGYHIVFALAGDPKNADDTSIYMFYQKVGETSIDSWKNAGRVFKDSDKFDANDSILKDQTQEWSGSATFTSDGKIRLFYTDFSGKHYGKQTLTTAQVNVSASDSSLNINGVEDYKSIFDGDGKTYQNVQQFIDEGNYSSGDNHTLRDPHYVEDKGHKYLVFEANTGTEDGYQGEESLFNKAYYGKSTSFFRQESQKLLQSDKKRTAELANGALGMIELNDDYTLKKVMKPLIASNTVTDEIERANVFKMNGKWYLFTDSRGSKMTIDGITSNDIYMLGYVSNSLTGPYKPLNKTGLVLKMDLDPNDVTFTYSHFAVPQAKGNNVVITSYMTNRGFYADKQSTFAPSFLLNIKGKKTSVVKDSILEQGQLTVNK", "length": 473, "reference_go_mf": ["GO:0050053"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_43bfff21630c71402aa6"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_876_1p3d_assembly1", "enzyme_name": "UDP-N-acetylmuramate---L-alanine ligase", "ec": ["6.3.2.8"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P45066", "alignment_score": 814.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [10, 473], "sequence": "MKHSHEEIRKIIPEMRRVQQIHFIGIGGAGMSGIAEILLNEGYQISGSDIADGVVTQRLAQAGAKIYIGHAEEHIEGASVVVVSSAIKDDNPELVTSKQKRIPVIQRAQMLAEIMRFRHGIAVAGTHGKTTTTAMISMIYTQAKLDPTFVNGGLVKSAGKNAHLGASRYLIAEADESDASFLHLQPMVSVVTNMEPDHMDTYEGDFEKMKATYVKFLHNLPFYGLAVMCADDPVLMELVPKVGRQVITYGFSEQADYRIEDYEQTGFQGHYTVICPNNERINVLLNVPGKHNALNATAALAVAKEEGIANEAILEALADFQGAGRRFDQLGEFIRPNGKVRLVDDYGHHPTEVGVTIKAAREGWGDKRIVMIFQPHRYSRTRDLFDDFVQVLSQVDALIMLDVYAAGEAPIVGADSKSLCRSIRNLGKVDPILVSDTSQLGDVLDQIIQDGDLILAQGAGSVSKISRGLAESWKN", "length": 475, "reference_go_mf": ["GO:0005524", "GO:0008763"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_188e02402461d06b3570"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_878_1pgs_assembly1", "enzyme_name": "peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase", "ec": ["3.5.1.52"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P21163", "alignment_score": 619.0, "observed_coverage": 1.0, "aligned_identity": 0.9967845659163987, "canonical_span": [43, 354], "sequence": "MRKLLIFSISAYLMAGIVSCKGVDSATPVTEDRLALNAVNAPADNTVNIKTFDKVKNAFGDGLSQSAEGTFTFPADVTTVKTIKMFIKNECPNKTCDEWDRYANVYVKNKTTGEWYEIGRFITPYWVGTEKLPRGLEIDVTDFKSLLSGNTELKIYTETWLAKGREYSVDFDIVYGTPDYKYSAVVPVIQYNKSSIDGVPYGKAHTLGLKKNIQLPTNTEKAYLRTTISGWGHAKPYDAGSRGCAEWCFRTHTIAINNANTFQHQLGALGCSANPINNQSPGNWAPDRAGWCPGMAVPTRIDVLNNSLTGSTFSYEYKFQSWTNNGTNGDAFYAISSFVIAKSNTPISAPVVTN", "length": 354, "reference_go_mf": ["GO:0016715", "GO:0000224"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_fee7c47fd9107c661bce"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_879_1pj5_assembly1", "enzyme_name": "dimethylglycine oxidase (tetrahydrofolate utilising)", "ec": ["1.5.3.-"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q9AGP8", "alignment_score": 1654.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [3, 830], "sequence": "MASTPRIVIIGAGIVGTNLADELVTRGWNNITVLDQGPLNMPGGSTSHAPGLVFQTNPSKTMASFAKYTVEKLLSLTEDGVSCFNQVGGLEVATTETRLADLKRKLGYAAAWGIEGRLLSPAECQELYPLLDGENILGGLHVPSDGLASAARAVQLLIKRTESAGVTYRGSTTVTGIEQSGGRVTGVQTADGVIPADIVVSCAGFWGAKIGAMIGMAVPLLPLAHQYVKTTPVPAQQGRNDQPNGARLPILRHQDQDLYYREHGDRYGIGSYAHRPMPVDVDTLGAYAPETVSEHHMPSRLDFTLEDFLPAWEATKQLLPALADSEIEDGFNGIFSFTPDGGPLLGESKELDGFYVAEAVWVTHSAGVAKAMAELLTTGRSETDLGECDITRFEDVQLTPEYVSETSQQNFVEIYDVLHPLQPRLSPRNLRVSPFHARHKELGAFFLEAGGWERPYWFEANAALLKEMPAEWLPPARDAWSGMFSSPIAAAEAWKTRTAVAMYDMTPLKRLEVSGPGALKLLQELTTADLAKKPGAVTYTLLLDHAGGVRSDITVARLSEDTFQLGANGNIDTAYFERAARHQTQSGSATDWVQVRDTTGGTCCIGLWGPLARDLVSKVSDDDFTNDGLKYFRAKNVVIGGIPVTAMRLSYVGELGWELYTSADNGQRLWDALWQAGQPFGVIAAGRAAFSSLRLEKGYRSWGTDMTTEHDPFEAGLGFAVKMAKESFIGKGALEGRTEEASARRLRCLTIDDGRSIVLGKEPVFYKEQAVGYVTSAAYGYTVAKPIAYSYLPGTVSVGDSVDIEYFGRRITATVTEDPLYDPKMTRLRG", "length": 830, "reference_go_mf": ["GO:0047866"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_ba7ff412bed2dcb4bb1a"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_880_1pmi_assembly1", "enzyme_name": "mannose-6-phosphate isomerase (type I)", "ec": ["5.3.1.8"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P34948", "alignment_score": 880.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 441], "sequence": "MSSEKLFRIQCGYQNYDWGKIGSSSAVAQFVHNSDPSITIDETKPYAELWMGTHPSVPSKAIDLNNQTLRDLVTAKPQEYLGESIITKFGSSKELPFLFKVLSIEKVLSIQAHPDKKLGAQLHAADPKNYPDDNHKPEMAIAVTDFEGFCGFKPLDQLAKTLATVPELNEIIGQELVDEFISGIKLPAEVGSQDDVNNRKLLQKVFGKLMNTDDDVIKQQTAKLLERTDREPQVFKDIDSRLPELIQRLNKQFPNDIGLFCGCLLLNHVGLNKGEAMFLQAKDPHAYISGDIIECMAASDNVVRAGFTPKFKDVKNLVEMLTYSYESVEKQKMPLQEFPRSKGDAVKSVLYDPPIAEFSVLQTIFDKSKGGKQVIEGLNGPSIVIATNGKGTIQITGDDSTKQKIDTGYVFFVAPGSSIELTADSANQDQDFTTYRAFVEA", "length": 441, "reference_go_mf": ["GO:0004476", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_7a77ea75009952e4b58b"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_881_1pud_assembly1", "enzyme_name": "tRNA-guanine transglycosylase", "ec": ["2.4.2.29"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P28720", "alignment_score": 741.0, "observed_coverage": 1.0, "aligned_identity": 0.9973118279569892, "canonical_span": [10, 382], "sequence": "MVEATAQETDRPRFSFSIAAREGKARTGTIEMKRGVIRTPAFMPVGTAATVKALKPETVRATGADIILGNTYHLMLRPGAERIAKLGGLHSFMGWDRPILTDSGGYQVMSLSSLTKQSEEGVTFKSHLDGSRHMLSPERSIEIQHLLGSDIVMAFDECTPYPATPSRAASSMERSMRWAKRSRDAFDSRKEQAENAALFGIQQGSVFENLRQQSADALAEIGFDGYAVGGLAVGEGQDEMFRVLDFSVPMLPDDKPHYLMGVGKPDDIVGAVERGIDMFDCVLPTRSGRNGQAFTWDGPINIRNARFSEDLTPLDSECHCAVCQKWSRAYIHHLIRAGEILGAMLMTEHNIAFYQQLMQKIRDSISEGRFSQFAQDFRARYFARNS", "length": 386, "reference_go_mf": ["GO:0008479"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_9b961bd63c8d3c0de609"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_883_2dln_assembly1", "enzyme_name": "D-alanine---D-alanine ligase", "ec": ["6.3.2.4"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P07862", "alignment_score": 612.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 306], "sequence": "MTDKIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKEVDVTQLKSMGFQKVFIALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRILELAD", "length": 306, "reference_go_mf": ["GO:0005524", "GO:0008716", "GO:0046872", "GO:0042803"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_59a1d6e62f364a06e598"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_884_1ses_assembly1", "enzyme_name": "serine---tRNA ligase", "ec": ["6.1.1.11"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P34945", "alignment_score": 842.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 421], "sequence": "MVDLKRLRQEPEVFHRAIREKGVALDLEALLALDREVQELKKRLQEVQTERNQVAKRVPKAPPEEKEALIARGKALGEEAKRLEEALREKEARLEALLLQVPLPPWPGAPVGGEEANREIKRVGGPPEFSFPPLDHVALMEKNGWWEPRISQVSGSRSYALKGDLALYELALLRFAMDFMARRGFLPMTLPSYAREKAFLGTGHFPAYRDQVWAIAETDLYLTGTAEVVLNALHSGEILPYEALPLRYAGYAPAFRSEAGSFGKDVRGLMRVHQFHKVEQYVLTEASLEASDRAFQELLENAEEILRLLELPYRLVEVATGDMGPGKWRQVDIEVYLPSEGRYRETHSCSALLDWQARRANLRYRDPEGRVRYAYTLNNTALATPRILAMLLENHQLQDGRVRVPQALIPYMGKEVLEPCG", "length": 421, "reference_go_mf": ["GO:0005524", "GO:0042802", "GO:0042803", "GO:0070905", "GO:0004828", "GO:0000049"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_40e4a65924a1b83a05ba"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_885_2cja_assembly1", "enzyme_name": "Serine-tRNA ligase (archaeal)", "ec": ["6.1.1.11"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q46AN5", "alignment_score": 827.5, "observed_coverage": 0.9956896551724138, "aligned_identity": 1.0, "canonical_span": [1, 502], "sequence": "MKLQFNLKAYFKTSADPTPAKDAIAALFEEANSTLLTRGAPEGQGAKVTEWKLGEDRIELTLQSGRYVRVHDAIFRLRKQLAEALGKKYKIGIRGIEVESFIIKVPADHELRMLKVPYIKSMENIEGGIQLELEVGEAEMKNRVPDRILTLLEEKIEAAQYGAKAEHWNLLWQREPMEHPFKEDPTQAMMKEGWLKRGSSRGQWIHGPQSARIFRTFEKIVLEELLEPLGYREMIFPKLVTWEVWMKSGHAKGVYPEIYYVCPPQTRDPDYWEEVADYYKVTHEVPTKLIKEKIAEPIGGMCYAQCPPFWMYVAGETLPNEEIPVKVFDRSGTSHRYESGGIHGIERVDEFHRIEIVWIGTKEEVLKCAEELHDRYMHIFNDILDIEWRKARVTPWFMAQEGLLGLAEENTVGTTDYEACLPYRGPDGEWLEFQNVSINGDKYPKGFNVKLQSGDELWSGCSGVGLERWAAVFLAQKGLDPANWPEEFRNRVGEMPKGIRFL", "length": 502, "reference_go_mf": ["GO:0005524", "GO:0004828", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_f2aad5e803f817eb1917"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_889_2pgd_assembly1", "enzyme_name": "phosphogluconate dehydrogenase (decarboxylating)", "ec": ["1.1.1.44"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00349", "alignment_score": 946.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 474], "sequence": "MAQADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVLGAHSLEEMVSKLKKPRRIILLVKAGQAVDNFIEKLVPLLDIGDIIIDGGNSEYRDTMRRCRDLKDKGILFVGSGVSGGEDGARYGPSLMPGGNKEAWPHIKAIFQGIAAKVGTGEPCCDWVGDDGAGHFVKMVHNGIEYGDMQLICEAYHLMKDVLGLGHKEMAKAFEEWNKTELDSFLIEITASILKFQDADGKHLLPKIRDSAGQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQASKKLKGPQNIPFEGDKKSFLEDIRKALYASKIISYAQGFMLLRQAATEFGWTLNYGGIALMWRGGCIIRSVFLGKIKDAFDRNPGLQNLLLDDFFKSAVENCQDSWRRAISTGVQAGIPMPCFTTALSFYDGYRHAMLPANLIQAQRDYFGAHTYELLAKPGQFIHTNWTGHGGSVSSSSYNA", "length": 483, "reference_go_mf": ["GO:0050661", "GO:0004616"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_00d16486b9a0f438ba23"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_88_1hxq_assembly1", "enzyme_name": "UDP-glucose-hexose-1-phosphate uridylyltransferase", "ec": ["2.7.7.12"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P09148", "alignment_score": 671.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 348], "sequence": "MTQFNPVDHPHRRYNPLTGQWILVSPHRAKRPWQGAQETPAKQVLPAHDPDCFLCAGNVRVTGDKNPDYTGTYVFTNDFAALMSDTPDAPESHDPLMRCQSARGTSRVICFSPDHSKTLPELSVAALTEIVKTWQEQTAELGKTYPWVQVFENKGAAMGCSNPHPHGQIWANSFLPNEAEREDRLQKEYFAEQKSPMLVDYVQRELADGSRTVVETEHWLAVVPYWAAWPFETLLLPKAHVLRITDLTDAQRSDLALALKKLTSRYDNLFQCSFPYSMGWHGAPFNGEENQHWQLHAHFYPPLLRSATVRKFMVGYEMLAETQRDLTAEQAAERLRAVSDIHFRESGV", "length": 348, "reference_go_mf": ["GO:0008198", "GO:0004335", "GO:0008108", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_a70a62bfbc047c3650d4"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_890_1yve_assembly2", "enzyme_name": "ketol-acid reductoisomerase", "ec": ["1.1.1.86"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q01292", "alignment_score": 1020.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [85, 595], "sequence": "MAATAATTFSLSSSSSTSAAASKALKQSPKPSALNLGFLGSSSTIKACRSLKAARVLPSGANGGGSALSAQMVSAPSINTPSATTFDFDSSVFKKEKVTLSGHDEYIVRGGRNLFPLLPDAFKGIKQIGVIGWGSQAPAQAQNLKDSLTEAKSDVVVKIGLRKGSNSFAEARAAGFSEENGTLGDMWETISGSDLVLLLISDSAQADNYEKVFSHMKPNSILGLSHGFLLGHLQSLGQDFPKNISVIAVCPKGMGPSVRRLYVQGKEVNGAGINSSFAVHQDVDGRATDVALGWSIALGSPFTFATTLEQEYKSDIFGERGILLGAVHGIVECLFRRYTESGMSEDLAYKNTVECITGVISKTISTKGMLALYNSLSEEGKKDFQAAYSASYYPSMDILYECYEDVASGSEIRSVVLAGRRFYEKEGLPAFPMGKIDQTRMWKVGEKVRSVRPAGDLGPLYPFTAGVYVALMMAQIEILRKKGHSYSEIINESVIEAVDSLNPFMHARGVSFMVDNCSTTARLGSRKWAPRFDYILSQQALVAVDNGAPINQDLISNFLSDPVHEAIGVCAQLRPSVDISVTADADFVRPELRQA", "length": 595, "reference_go_mf": ["GO:0004455", "GO:0000287", "GO:0070402", "GO:0042803"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_d853a981f908a8fec138"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_891_1ybv_assembly1", "enzyme_name": "Tetrahydroxynaphthalene reductase", "ec": ["1.1.1.252"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q12634", "alignment_score": 531.0, "observed_coverage": 1.0, "aligned_identity": 0.9888888888888889, "canonical_span": [13, 283], "sequence": "MPAVTQPRGESKYDAIPGPLGPQSASLEGKVALVTGAGRGIGREMAMELGRRGCKVIVNYANSTESAEEVVAAIKKNGSDAACVKANVGVVEDIVRMFEEAVKIFGKLDIVCSNSGVVSFGHVKDVTPEEFDRVFTINTRGQFFVAREAYKHLEIGGRLILMGSITGQAKAVPKHAVYSGSKGAIETFARCMAIDMADKKITVNVVAPGGIKTDMYHAVCREYIPNGENLSNEEVDEYAASAWSPLHRVGLPIDIARVVCFLASNDGGWVTGKVIGIDGGACM", "length": 283, "reference_go_mf": ["GO:0047039"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_58e3ed5d2027b7dbc51c"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_896_2pec_assembly1", "enzyme_name": "pectate lyase C (polysaccharide lyase 1 family)", "ec": ["4.2.2.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P11073", "alignment_score": 704.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [22, 374], "sequence": "MKSLITPITAGLLLALSQPLLAATDTGGYAATAGGNVTGAVSKTATSMQDIVNIIDAARLDANGKKVKGGAYPLVITYTGNEDSLINAAAANICGQWSKDPRGVEIKEFTKGITIIGANGSSANFGIWIKKSSDVVVQNMRIGYLPGGAKDGDMIRVDDSPNVWVDHNELFAANHECDGTPDNDTTFESAVDIKGASNTVTVSYNYIHGVKKVGLDGSSSSDTGRNITYHHNYYNDVNARLPLQRGGLVHAYNNLYTNITGSGLNVRQNGQALIENNWFEKAINPVTSRYDGKNFGTWVLKGNNITKPADFSTYSITWTADTKPYVNADSWTSTGTFPTVAYNYSPVSAQCVKDKLPGYAGVGKNLATLTSTACK", "length": 375, "reference_go_mf": ["GO:0030570"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_48c9ab0516f86f65e67a"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_897_1pvi_assembly1", "enzyme_name": "type II site-specific deoxyribonuclease PvuII", "ec": ["3.1.21.4"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P23657", "alignment_score": 312.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 157], "sequence": "MSHPDLNKLLELWPHIQEYQDLALKHGINDIFQDNGGKLLQVLLITGLTVLPGREGNDAVDNAGQEYELKSINIDLTKGFSTHHHMNPVIIAKYRQVPWIFAIYRGIAIEAIYRLEPKDLEFYYDKWERKWYSDGHKDINNPKIPVKYVMEHGTKIY", "length": 157, "reference_go_mf": ["GO:0009036"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_fd920945d4b55f835b00"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_898_1qam_assembly1", "enzyme_name": "23S rRNA (adenine2085-N6)-dimethyltransferase", "ec": ["2.1.1.184"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P13956", "alignment_score": 470.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [9, 244], "sequence": "MNEKNIKHSQNFITSKHNIDKIMTNIRLNEHDNIFEIGSGKGHFTLELVQRCNFVTAIEIDHKLCKTTENKLVDHDNFQVLNKDILQFKFPKNQSYKIFGNIPYNISTDIIRKIVFDSIADEIYLIVEYGFAKRLLNTKRSLALFLMAEVDISILSMVPREYFHPKPKVNSSLIRLNRKKSRISHKDKQKYNYFVMKWVNKEYKKIFTKNQFNNSLKHAGIDDLNNISFEQFLSLFNSYKLFNK", "length": 244, "reference_go_mf": ["GO:0052910", "GO:0000179"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_327fe0cb11294f476b0b"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_89_1ps1_assembly1", "enzyme_name": "pentalenene synthase", "ec": ["4.2.3.7"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q55012", "alignment_score": 599.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [2, 313], "sequence": "MPQDVDFHIPLPGRQSPDHARAEAEQLAWPRSLGLIRSDAAAERHLRGGYADLASRFYPHATGADLDLGVDLMSWFFLFDDLFDGPRGENPEDTKQLTDQVAAALDGPLPDTAPPIAHGFADIWRRTCEGMTPAWCARSARHWRNYFDGYVDEAESRFWNAPCDSAAQYLAMRRHTIGVQPTVDLAERAGRFEVPHRVFDSAVMSAMLQIAVDVNLLLNDIASLEKEEARGEQNNMVMILRREHGWSKSRSVSHMQNEVRARLEQYLLLESCLPKVGEIYQLDTAEREALERYRTDAVRTVIRGSYDWHRSSGRYDAEFALAAGAQGYLEELGSSAH", "length": 337, "reference_go_mf": ["GO:0050467"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_a9775f6e8a37cb20b433"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_8_1qpr_assembly1", "enzyme_name": "nicotinate-nucleotide diphosphorylase (carboxylating) (type II)", "ec": ["2.4.2.19"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P9WJJ7", "alignment_score": 568.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 285], "sequence": "MGLSDWELAAARAAIARGLDEDLRYGPDVTTLATVPASATTTASLVTREAGVVAGLDVALLTLNEVLGTNGYRVLDRVEDGARVPPGEALMTLEAQTRGLLTAERTMLNLVGHLSGIATATAAWVDAVRGTKAKIRDTRKTLPGLRALQKYAVRTGGGVNHRLGLGDAALIKDNHVAAAGSVVDALRAVRNAAPDLPCEVEVDSLEQLDAVLPEKPELILLDNFAVWQTQTAVQRRDSRAPTVMLESSGGLSLQTAATYAETGVDYLAVGALTHSVRVLDIGLDM", "length": 285, "reference_go_mf": ["GO:0004514"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_9e7b5c46fb736aadb6dd"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P9WJJ7", "alignment_score": 568.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 285], "sequence": "MGLSDWELAAARAAIARGLDEDLRYGPDVTTLATVPASATTTASLVTREAGVVAGLDVALLTLNEVLGTNGYRVLDRVEDGARVPPGEALMTLEAQTRGLLTAERTMLNLVGHLSGIATATAAWVDAVRGTKAKIRDTRKTLPGLRALQKYAVRTGGGVNHRLGLGDAALIKDNHVAAAGSVVDALRAVRNAAPDLPCEVEVDSLEQLDAVLPEKPELILLDNFAVWQTQTAVQRRDSRAPTVMLESSGGLSLQTAATYAETGVDYLAVGALTHSVRVLDIGLDM", "length": 285, "reference_go_mf": ["GO:0004514"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_9e7b5c46fb736aadb6dd"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_900_1qe3_assembly1", "enzyme_name": "para-nitrobenzyl esterase", "ec": ["3.1.1.-"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P37967", "alignment_score": 882.0, "observed_coverage": 1.0, "aligned_identity": 0.9764453961456103, "canonical_span": [1, 484], "sequence": "MTHQIVTTQYGKVKGTTENGVHKWKGIPYAKPPVGQWRFKAPEPPEVWEDVLDATAYGSICPQPSDLLSLSYTELPRQSEDCLYVNVFAPDTPSKNLPVMVWIHGGAFYLGAGSEPLYDGSKLAAQGEVIVVTLNYRLGPFGFLHLSSFNEAYSDNLGLLDQAAALKWVRENISAFGGDPDNVTVFGESAGGMSIAALLAMPAAKGLFQKAIMESGASRTMTKEQAASTSAAFLQVLGINEGQLDKLHTVSAEDLLKAADQLRIAEKENIFQLFFQPALDPKTLPEEPEKAIAEGAASGIPLLIGTTRDEGYLFFTPDSDVHSQETLDAALEYLLGKPLAEKVADLYPRSLESQIHMMTDLLFWRPAVAYASAQSHYAPVWMYRFDWHPKKPPYNKAFHALELPFVFGNLDGLERMAKAEITDEVKQLSHTIQSAWITFAKTGNPSTEAVNWPAYHEETRETLILDSEITIENDPESEKRQKLFPSKGE", "length": 489, "reference_go_mf": ["GO:0004104"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_7092bad05ec25b6faaa9"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_901_1qfm_assembly1", "enzyme_name": "prolyl oligopeptidase", "ec": ["3.4.21.26"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P23687", "alignment_score": 1380.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 710], "sequence": "MLSFQYPDVYRDETAIQDYHGHKVCDPYAWLEDPDSEQTKAFVEAQNKITVPFLEQCPIRGLYKERMTELYDYPKYSCHFKKGKRYFYFYNTGLQNQRVLYVQDSLEGEARVFLDPNILSDDGTVALRGYAFSEDGEYFAYGLSASGSDWVTIKFMKVDGAKELPDVLERVKFSCMAWTHDGKGMFYNAYPQQDGKSDGTETSTNLHQKLYYHVLGTDQSEDILCAEFPDEPKWMGGAELSDDGRYVLLSIREGCDPVNRLWYCDLQQESNGITGILKWVKLIDNFEGEYDYVTNEGTVFTFKTNRHSPNYRLINIDFTDPEESKWKVLVPEHEKDVLEWVACVRSNFLVLCYLHDVKNTLQLHDLATGALLKIFPLEVGSVVGYSGQKKDTEIFYQFTSFLSPGIIYHCDLTKEELEPRVFREVTVKGIDASDYQTVQIFYPSKDGTKIPMFIVHKKGIKLDGSHPAFLYGYGGFNISITPNYSVSRLIFVRHMGGVLAVANIRGGGEYGETWHKGGILANKQNCFDDFQCAAEYLIKEGYTSPKRLTINGGSNGGLLVATCANQRPDLFGCVIAQVGVMDMLKFHKYTIGHAWTTDYGCSDSKQHFEWLIKYSPLHNVKLPEADDIQYPSMLLLTADHDDRVVPLHSLKFIATLQYIVGRSRKQNNPLLIHVDTKAGHGAGKPTAKVIEEVSDMFAFIARCLNIDWIP", "length": 710, "reference_go_mf": ["GO:0004252"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_ac01a6aa7f6bbd2bdc94"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_902_2nac_assembly1", "enzyme_name": "NAD-dependent formate dehydrogenase", "ec": ["1.17.1.9"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P33160", "alignment_score": 748.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 375], "sequence": "MAKVLCVLYDDPVDGYPKTYARDDLPKIDHYPGGQTLPTPKAIDFTPGQLLGSVSGELGLRKYLESNGHTLVVTSDKDGPDSVFERELVDADVVISQPFWPAYLTPERIAKAKNLKLALTAGIGSDHVDLQSAIDRNVTVAEVTYCNSISVAEHVVMMILSLVRNYLPSHEWARKGGWNIADCVSHAYDLEAMHVGTVAAGRIGLAVLRRLAPFDVHLHYTDRHRLPESVEKELNLTWHATREDMYPVCDVVTLNCPLHPETEHMINDETLKLFKRGAYIVNTARGKLCDRDAVARALESGRLAGYAGDVWFPQPAPKDHPWRTMPYNGMTPHISGTTLTAQARYAAGTREILECFFEGRPIRDEYLIVQGGALAGTGAHSYSKGNATGGSEEAAKFKKAV", "length": 401, "reference_go_mf": ["GO:0008863", "GO:0051287", "GO:0016616"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_aaf788bbb384129ffbfc"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_903_1nir_assembly1", "enzyme_name": "nitrite reductase (cytochrome cd1 type)", "ec": ["1.7.2.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P24474", "alignment_score": 1076.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [30, 568], "sequence": "MPFGKPLVGTLLASLTLLGLATAHAKDDMKAAEQYQGAASAVDPAHVVRTNGAPDMSESEFNEAKQIYFQRCAGCHGVLRKGATGKPLTPDITQQRGQQYLEALITYGTPLGMPNWGSSGELSKEQITLMAKYIQHTPPQPPEWGMPEMRESWKVLVKPEDRPKKQLNDLDLPNLFSVTLRDAGQIALVDGDSKKIVKVIDTGYAVHISRMSASGRYLLVIGRDARIDMIDLWAKEPTKVAEIKIGIEARSVESSKFKGYEDRYTIAGAYWPPQFAIMDGETLEPKQIVSTRGMTVDTQTYHPEPRVAAIIASHEHPEFIVNVKETGKVLLVNYKDIDNLTVTSIGAAPFLHDGGWDSSHRYFMTAANNSNKVAVIDSKDRRLSALVDVGKTPHPGRGANFVHPKYGPVWSTSHLGDGSISLIGTDPKNHPQYAWKKVAELQGQGGGSLFIKTHPKSSHLYVDTTFNPDARISQSVAVFDLKNLDAKYQVLPIAEWADLGEGAKRVVQPEYNKRGDEVWFSVWNGKNDSSALVVVDDKTLKLKAVVKDPRLITPTGKFNVYNTQHDVY", "length": 568, "reference_go_mf": ["GO:0009055", "GO:0020037", "GO:0050418", "GO:0050421"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_3c4c71f59c27d5ef0859"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_904_1qgx_assembly1", "enzyme_name": "3'(2'),5'-bisphosphate nucleotidase", "ec": ["3.1.3.7"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P32179", "alignment_score": 708.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 355], "sequence": "MALERELLVATQAVRKASLLTKRIQSEVISHKDSTTITKNDNSPVTTGDYAAQTIIINAIKSNFPDDKVVGEESSSGLSDAFVSGILNEIKANDEVYNKNYKKDDFLFTNDQFPLKSLEDVRQIIDFGNYEGGRKGRFWCLDPIDGTKGFLRGEQFAVCLALIVDGVVQLGCIGCPNLVLSSYGAQDLKGHESFGYIFRAVRGLGAFYSPSSDAESWTKIHVRHLKDTKDMITLEGVEKGHSSHDEQTAIKNKLNISKSLHLDSQAKYCLLALGLADVYLRLPIKLSYQEKIWDHAAGNVIVHEAGGIHTDAMEDVPLDFGNGRTLATKGVIASSGPRELHDLVVSTSCDVIQSRNA", "length": 357, "reference_go_mf": ["GO:0008441"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_15796657d5760fb386fc"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_905_1qho_assembly1", "enzyme_name": "glucan 1,4-alpha-maltohydrolase", "ec": ["3.2.1.133"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P19531", "alignment_score": 1372.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [33, 719], "sequence": "MKKKTLSLFVGLMLLIGLLFSGSLPYNPNAAEASSSASVKGDVIYQIIIDRFYDGDTTNNNPAKSYGLYDPTKSKWKMYWGGDLEGVRQKLPYLKQLGVTTIWLSPVLDNLDTLAGTDNTGYHGYWTRDFKQIEEHFGNWTTFDTLVNDAHQNGIKVIVDFVPNHSTPFKANDSTFAEGGALYNNGTYMGNYFDDATKGYFHHNGDISNWDDRYEAQWKNFTDPAGFSLADLSQENGTIAQYLTDAAVQLVAHGADGLRIDAVKHFNSGFSKSLADKLYQKKDIFLVGEWYGDDPGTANHLEKVRYANNSGVNVLDFDLNTVIRNVFGTFTQTMYDLNNMVNQTGNEYKYKENLITFIDNHDMSRFLSVNSNKANLHQALAFILTSRGTPSIYYGTEQYMAGGNDPYNRGMMPAFDTTTTAFKEVSTLAGLRRNNAAIQYGTTTQRWINNDVYIYERKFFNDVVLVAINRNTQSSYSISGLQTALPNGSYADYLSGLLGGNGISVSNGSVASFTLAPGAVSVWQYSTSASAPQIGSVAPNMGIPGNVVTIDGKGFGTTQGTVTFGGVTATVKSWTSNRIEVYVPNMAAGLTDVKVTAGGVSSNLYSYNILSGTQTSVVFTVKSAPPTNLGDKIYLTGNIPELGNWSTDTSGAVNNAQGPLLAPNYPDWFYVFSVPAGKTIQFKFFIKRADGTIQWENGSNHVATTPTGATGNITVTWQN", "length": 719, "reference_go_mf": ["GO:0004556", "GO:0043169", "GO:0043897", "GO:2001070"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_5282a6256580c98f5b46"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_906_1qib_assembly1", "enzyme_name": "gelatinase A", "ec": ["3.4.24.24"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P08253", "alignment_score": 220.5, "observed_coverage": 1.0, "aligned_identity": 0.9813664596273292, "canonical_span": [114, 449], "sequence": "MEALMARGALTGPLRALCLLGCLLSHAAAAPSPIIKFPGDVAPKTDKELAVQYLNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASPDIDLGTGPTPTLGPVTPEICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC", "length": 660, "reference_go_mf": ["GO:0004175", "GO:0001968", "GO:0004222", "GO:0008237", "GO:0004252", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_e4520c62aed3a6fd2854"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_907_1rbl_assembly1", "enzyme_name": "ribulose-bisphosphate carboxylase (type I)", "ec": ["4.1.1.39"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00880", "alignment_score": 931.0, "observed_coverage": 1.0, "aligned_identity": 0.9978586723768736, "canonical_span": [5, 472], "sequence": "MPKTQSAAGYKAGVKDYKLTYYTPDYTPKDTDLLAAFRFSPQPGVPADEAGAAIAAESSTGTWTTVWTDLLTDMDRYKGKCYHIEPVQGEENSYFAFIAYPLDLFEEGSVTNILTSIVGNVFGFKAIRSLRLEDIRFPVALVKTFQGPPHGIQVERDLLNKYGRPMLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENINSQPFQRWRDRFLFVADAIHKSQAETGEIKGHYLNVTAPTCEEMMKRAEFAKELGMPIIMHDFLTAGFTANTTLAKWCRDNGVLLHIHRAMHAVIDRQRNHGIHFRVLAKCLRLSGGDHLHSGTVVGKLEGDKASTLGFVDLMREDHIEADRSRGVFFTQDWASMPGVLPVASGGIHVWHMPALVEIFGDDSVLQFGGGTLGHPWGNAPGATANRVALEACVQARNEGRDLYREGGDILREAGKWSPELAAALDLWKEIKFEFETMDKL", "length": 472, "reference_go_mf": ["GO:0000287", "GO:0016984"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_41299ef94b2d63b26bf4"}, "alternative_alignments": [{"accession": "P04716", "alignment_score": 7.0, "observed_coverage": 0.017130620985010708, "aligned_identity": 0.625, "canonical_span": [5, 13], "length": 111, "reference_go_mf": ["GO:0016984"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_908_1rtu_assembly1", "enzyme_name": "ribonuclease U2", "ec": ["4.6.1.20"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00654", "alignment_score": 220.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 114], "sequence": "CDIPQSTNCGGNVYSNDDINTAIQGALDDVANGDRPDNYPHQYYDEASEDITLCCGSGPWSEFPLVYNGPYYSSRDNYVSPGPDRVIYQTNTGEFCATVTHTGAASYDGFTQCS", "length": 114, "reference_go_mf": ["GO:0033899", "GO:0003723"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_232a426522f9aa088fb8"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_90_1b3r_assembly1", "enzyme_name": "adenosylhomocysteinase", "ec": ["3.3.1.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P10760", "alignment_score": 856.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [4, 432], "sequence": "MADKLPYKVADIGLAAWGRKALDIAENEMPGLMRMREMYSASKPLKGARIAGCLHMTVETAVLIETLVALGAEVRWSSCNIFSTQDHAAAAIAKAGIPVFAWKGETDEEYLWCIEQTLHFKDGPLNMILDDGGDLTNLIHTKHPQLLSGIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACKEGNIFVTTTGCVDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYLLKNGHRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMPINGPFKPDHYRY", "length": 432, "reference_go_mf": ["GO:0004013", "GO:0098604", "GO:0030554", "GO:0005507", "GO:0042802", "GO:0051287"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_3c5d40532be8e361334c"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_910_1std_assembly1", "enzyme_name": "scytalone dehydratase", "ec": ["4.2.1.94"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P56221", "alignment_score": 324.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [8, 170], "sequence": "MGSQVQKSDEITFSDYLGLMTCVYEWADSYDSKDWDRLRKVIAPTLRIDYRSFLDKLWEAMPAEEFVGMVSSKQVLGDPTLRTQHFIGGTRWEKVSEDEVIGYHQLRVPHQRYKDTTMKEVTMKGHAHSANLHWYKKIDGVWKFAGLKPDIRWGEFDFDRIFEDGRETFGDK", "length": 172, "reference_go_mf": ["GO:0030411"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_1b58ac6577a9ffacce9a"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_912_1tyf_assembly1", "enzyme_name": "endopeptidase Clp", "ec": ["3.4.21.92"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0A6G7", "alignment_score": 366.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [24, 207], "sequence": "MSYSGERDNFAPHMALVPMVIEQTSRGERSFDIYSRLLKERVIFLTGQVEDHMANLIVAQMLFLEAENPEKDIYLYINSPGGVITAGMSIYDTMQFIKPDVSTICMGQAASMGAFLLTAGAKGKRFCLPNSRVMIHQPLGGYQGQATDIEIHAREILKVKGRMNELMALHTGQSLEQIERDTERDRFLSAPEAVEYGLVDSILTHRN", "length": 207, "reference_go_mf": ["GO:0004176", "GO:0051117", "GO:0042802", "GO:0004252", "GO:0008236"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_b027a0b811987bd858a3"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_914_1uro_assembly1", "enzyme_name": "uroporphyrinogen decarboxylase", "ec": ["4.1.1.37"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P06132", "alignment_score": 714.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [9, 366], "sequence": "MEANGLGPQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCRSPEACCELTLQPLRRFPLDAAIIFSDILVVPQALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPLIGFAGAPWTLMTYMVEGGGSSTMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMIIFAKDGHFALEELAQAGYEVVGLDWTVAPKKARECVGKTVTLQGNLDPCALYASEEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN", "length": 367, "reference_go_mf": ["GO:0004853"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_42c890975b323a20df95"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_915_1vid_assembly1", "enzyme_name": "catechol O-methyltransferase", "ec": ["2.1.1.6"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P22734", "alignment_score": 426.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [46, 259], "sequence": "MPLAAVSLGLLLLALLLLLRHLGWGLVTIFWFEYVLQPVHNLIMGDTKEQRILRYVQQNAKPGDPQSVLEAIDTYCTQKEWAMNVGDAKGQIMDAVIREYSPSLVLELGAYCGYSAVRMARLLQPGARLLTMEMNPDYAAITQQMLNFAGLQDKVTILNGASQDLIPQLKKKYDVDTLDMVFLDHWKDRYLPDTLLLEKCGLLRKGTVLLADNVIVPGTPDFLAYVRGSSSFECTHYSSYLEYMKVVDGLEKAIYQGPSSPDKS", "length": 264, "reference_go_mf": ["GO:0016206", "GO:0000287"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_6090164565ad94333335"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_916_4z71_assembly1", "enzyme_name": "inorganic diphosphatase", "ec": ["3.6.1.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P9WI55", "alignment_score": 318.0, "observed_coverage": 0.99375, "aligned_identity": 1.0, "canonical_span": [0, 159], "sequence": "MQFDVTIEIPKGQRNKYEVDHETGRVRLDRYLYTPMAYPTDYGFIEDTLGDDGDPLDALVLLPQPVFPGVLVAARPVGMFRMVDEHGGDDKVLCVPAGDPRWDHVQDIGDVPAFELDAIKHFFVHYKDLEPGKFVKAADWVDRAEAEAEVQRSVERFKAGTH", "length": 162, "reference_go_mf": ["GO:0004427", "GO:0000287"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_b9db7a702b41b067573d"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_917_1xgm_assembly1", "enzyme_name": "methionyl aminopeptidase", "ec": ["3.4.11.18"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P56218", "alignment_score": 590.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 295], "sequence": "MDTEKLMKAGEIAKKVREKAIKLARPGMLLLELAESIEKMIMELGGKPAFPVNLSINEIAAHYTPYKGDTTVLKEGDYLKIDVGVHIDGFIADTAVTVRVGMEEDELMEAAKEALNAAISVARAGVEIKELGKAIENEIRKRGFKPIVNLSGHKIERYKLHAGISIPNIYRPHDNYVLKEGDVFAIEPFATIGAGQVIEVPPTLIYMYVRDVPVRVAQARFLLAKIKREYGTLPFAYRWLQNDMPEGQLKLALKTLEKAGAIYGYPVLKEIRNGIVAQFEHTIIVEKDSVIVTTE", "length": 295, "reference_go_mf": ["GO:0004239", "GO:0046872", "GO:0070006"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_84168762dfe512aa5922"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_919_1xtc_assembly1", "enzyme_name": "NAD+---diphthamide ADP-ribosyltransferase", "ec": ["2.4.2.36"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P01555", "alignment_score": 378.0, "observed_coverage": 1.0, "aligned_identity": 0.9895833333333334, "canonical_span": [18, 210], "sequence": "MVKIIFVFFIFLSSFSYANDDKLYRADSRPPDEIKQSGGLMPRGQSEYFDRGTQMNINLYDHARGTQTGFVRHDDGYVSTSISLRSAHLVGQTILSGHSTYYIYVIATAPNMFNVNDVLGAYSPHPDEQEVSALGGIPYSQIYGWYRVHFGVLDEQLHRNRGYRDRYYSNLDIAPAADGYGLAGFPPEHRAWREEPWIHHAPPGCGNAPRSSMSNTCDEKTQSLGVKFLDEYQSKVKRQIFSGYQSDIDTHNRIKDEL", "length": 258, "reference_go_mf": ["GO:0005534", "GO:0008289", "GO:0090729"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_f87a5ec661573ff9e445"}, "alternative_alignments": [{"accession": "P01556", "alignment_score": 6.0, "observed_coverage": 0.03125, "aligned_identity": 0.6666666666666666, "canonical_span": [20, 26], "length": 124, "reference_go_mf": ["GO:0005534", "GO:0046812"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_91_1brw_assembly1", "enzyme_name": "pyrimidine-nucleoside phosphorylase", "ec": ["2.4.2.2"], "controls": [{"chain": "A", "status": "reference_mapping_uncertain", "selected": {"accession": "P77836", "alignment_score": 567.0, "observed_coverage": 0.9907621247113164, "aligned_identity": 0.7738927738927739, "canonical_span": [0, 429], "sequence": "MRMVDLIEKKRDGHALTKEEIQFIIEGYTKGDIPDYQMSALAMAIFFRGMNEEETAELTMAMVHSGDTIDLSRIEGIKVDKHSTGGVGDTTTLVLGPLVASVGVPVAKMSGRGLGHTGGTIDKLESVPGFHVEITNDEFIDLVNKNKIAVVGQSGNLTPADKKLYALRDVTATVNSIPLIASSIMSKKIAAGADAIVLDVKTGVGAFMKDLNDAKALAKAMVDIGNRVGRKTMAIISDMSQPLGYAIGNALEVKEAIDTLKGEGPEDFQELCLVLGSHMVYLAEKASSLEEARHMLEKAMKDGSALQTFKTFLAAQGGDASVVDDPSKLPQAKYIIELEAKEDGYVSEIVADAVGTAAMWLGAGRATKESTIDLAVGLVLRKKVGDAVKKGESLVTIYSNREQVDDVKQKLYENIRISATPVQAPTLIYDKIS", "length": 433, "reference_go_mf": ["GO:0004645", "GO:0047847", "GO:0009032", "GO:0004850"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_922_1mah_assembly1", "enzyme_name": "acetylcholinesterase", "ec": ["3.1.1.7"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P21836", "alignment_score": 1057.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [34, 574], "sequence": "MRPPWYPLHTPSLAFPLLFLLLSLLGGGARAEGREDPQLLVRVRGGQLRGIRLKAPGGPVSAFLGIPFAEPPVGSRRFMPPEPKRPWSGVLDATTFQNVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPASPTPVLIWIYGGGFYSGAASLDVYDGRFLAQVEGAVLVSMNYRVGTFGFLALPGSREAPGNVGLLDQRLALQWVQENIAAFGGDPMSVTLFGESAGAASVGMHILSLPSRSLFHRAVLQSGTPNGPWATVSAGEARRRATLLARLVGCPPGGAGGNDTELIACLRTRPAQDLVDHEWHVLPQESIFRFSFVPVVDGDFLSDTPEALINTGDFQDLQVLVGVVKDEGSYFLVYGVPGFSKDNESLISRAQFLAGVRIGVPQASDLAAEAVVLHYTDWLHPEDPTHLRDAMSAVVGDHNVVCPVAQLAGRLAAQGARVYAYIFEHRASTLTWPLWMGVPHGYEIEFIFGLPLDPSLNYTTEERIFAQRLMKYWTNFARTGDPNDPRDSKSPQWPPYTTAAQQYVSLNLKPLEVRRGLRAQTCAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKNQFDHYSKQERCSDL", "length": 614, "reference_go_mf": ["GO:0042166", "GO:0003990", "GO:0004104", "GO:0005518", "GO:0016787", "GO:0042802", "GO:0043236", "GO:0042803", "GO:0017171"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_ea93acf89722749feea7"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_925_2bii_assembly2", "enzyme_name": "Nitrate reductase [NADH]", "ec": ["1.7.1.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P49050", "alignment_score": 827.0, "observed_coverage": 1.0, "aligned_identity": 0.9975903614457832, "canonical_span": [61, 476], "sequence": "MDSIVTEVTYGLEIKKIKDITELPFPVRQDSPLTEVLPTDLKTKDNFVARDPDLLRLTGSHPFNSEPPLTKLYDSGFLTPVSLHFVRNHGPVPYVPDENILDWEVSIEGMVETPYKIKLSDIMEQFDIYSTPVTMVCAGNRRKEQNMVKKGAGFNWGAAGTSTSLWTGCMLGDVIGKARPSKRARFVWMEGADNPANGAYRTCIRLSWCMDPERCIMIAYQQNGEWLHPDHGKPLRVVIPGVIGGRSVKWLKKLVVSDRPSENWYHYFDNRVLPTMVTPEMAKSDDRWWKDERYAIYDLNLQTIICKPENQQVIKISEDEYEIAGFGYNGGGVRIGRIEVSLDKGKSWKLADIDYPEDRYREAGYFRLFGGLVNVCDRMSCLCWCFWKLKVPLSELARSKDILIRGMDERMMVQPRTMYWNVTSMLNNWWYRVAIIREGESLRFEHPVVANKPGGWMDRVKAEGGDILDNNWGEVDDTVKQAERRPHIDEDLEMMCNREKMDVVIKYSEFEAHKDSETEPWFAVKGQVFDGSSYLEDHPGGAQSILMVSGEDATDDFIAIHSSFAKKLLPSMHLGRLEEVSSVTKVKSVEQNVKREVLLDPRKWHKITLAEKEVISSDSRIFKFDLEHSEQLSGLPTGKHLFLRLKDSSGKYVMRAYTPKSSNSLRGRLEILIKVYFPNREYPNGGIMTNLIENLQVGNQIEVKGPVGEFEYVKCGHCSFNNKPYQMKHFVMISGGSGITPTYQVLQAIFSDPEDRTSVQLFFGNKKVDDILLREELDHIQEKYPEQFKVDYSLSDLDHLPENWSGVRGRLTFDILDTYVRGKKMGEYMLLVCGPPGMNGVVENWCNARKLDKQYVVYF", "length": 859, "reference_go_mf": ["GO:0071949", "GO:0020037", "GO:0030151", "GO:0043546", "GO:0050464", "GO:0008482"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_34ef64311e3844fd5e64"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_927_2fok_assembly1", "enzyme_name": "type II site-specific deoxyribonuclease FokI", "ec": ["3.1.21.4"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P14870", "alignment_score": 1085.5, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [4, 579], "sequence": "MVSKIRTFGWVQNPGKFENLKRVVQVFDRNSKVHNEVKNIKIPTLVKESKIQKELVAIMNQHDLIYTYKELVGTGTSIRSEAPCDAIIQATIADQGNKKGYIDNWSSDGFLRWAHALGFIEYINKSDSFVITDVGLAYSKSADGSAIEKEILIEAISSYPPAIRILTLLEDGQHLTKFDLGKNLGFSGESGFTSLPEGILLDTLANAMPKDKGEIRNNWEGSSDKYARMIGGWLDKLGLVKQGKKEFIIPTLGKPDNKEFISHAFKITGEGLKVLRRAKGSTKFTRVPKRVYWEMLATNLTDKEYVRTRRALILEILIKAGSLKIEQIQDNLKKLGFDEVIETIENDIKGLINTGIFIEIKGRFYQLKDHILQFVIPNRGVTKQLVKSELEEKKSELRHKLKYVPHEYIELIEIARNSTQDRILEMKVMEFFMKVYGYRGKHLGGSRKPDGAIYTVGSPIDYGVIVDTKAYSGGYNLPIGQADEMQRYVEENQTRNKHINPNEWWKVYPSSVTEFKFLFVSGHFKGNYKAQLTRLNHITNCNGAVLSVEELLIGGEMIKAGTLTLEEVRRKFNNGEINF", "length": 579, "reference_go_mf": ["GO:0003677", "GO:0009036"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_cdb57ee2195bcaaab973"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_928_2nmt_assembly1", "enzyme_name": "glycylpeptide N-tetradecanoyltransferase", "ec": ["2.3.1.97"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P14743", "alignment_score": 844.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [33, 455], "sequence": "MSEEDKAKKLENLLKLLQLNNDDTSKFTQEQKKAMKDHKFWRTQPVKDFDEKVVEEGPIDKPKTPEDISDKPLPLLSSFEWCSIDVDNKKQLEDVFVLLNENYVEDRDAGFRFNYTKEFFNWALKSPGWKKDWHIGVRVKETQKLVAFISAIPVTLGVRGKQVPSVEINFLCVHKQLRSKRLTPVLIKEITRRVNKCDIWHALYTAGIVLPAPVSTCRYTHRPLNWKKLYEVDFTGLPDGHTEEDMIAENALPAKTKTAGLRKLKKEDIDQVFELFKRYQSRFELIQIFTKEEFEHNFIGEESLPLDKQVIFSYVVEQPDGKITDFFSFYSLPFTILNNTKYKDLGIGYLYYYATDADFQFKDRFDPKATKALKTRLCELIYDACILAKNANMDVFNALTSQDNTLFLDDLKFGPGDGFLNFYLFNYRAKPITGGLNPDNSNDIKRRSNVGVVML", "length": 455, "reference_go_mf": ["GO:0004379"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_f11376fe334754b41d9c"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_929_2oat_assembly2", "enzyme_name": "ornithine aminotransferase", "ec": ["2.6.1.13"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P04181", "alignment_score": 808.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [35, 439], "sequence": "MFSKLAHLQRFAVLSRGVHSSVASATSVATKKTVQGPPTSDDIFEREYKYGAHNYHPLPVALERGKGIYLWDVEGRKYFDFLSSYSAVNQGHCHPKIVNALKSQVDKLTLTSRAFYNNVLGEYEEYITKLFNYHKVLPMNTGVEAGETACKLARKWGYTVKGIQKYKAKIVFAAGNFWGRTLSAISSSTDPTSYDGFGPFMPGFDIIPYNDLPALERALQDPNVAAFMVEPIQGEAGVVVPDPGYLMGVRELCTRHQVLFIADEIQTGLARTGRWLAVDYENVRPDIVLLGKALSGGLYPVSAVLCDDDIMLTIKPGEHGSTYGGNPLGCRVAIAALEVLEEENLAENADKLGIILRNELMKLPSDVVTAVRGKGLLNAIVIKETKDWDAWKVCLRLRDNGLLAKPTHGDIIRFAPPLVIKEDELRESIEIINKTILSF", "length": 439, "reference_go_mf": ["GO:0042802", "GO:0004587", "GO:0030170"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_58788980d9e3f8d58806"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_92_1dli_assembly1", "enzyme_name": "UDP-glucose 6-dehydrogenase", "ec": ["1.1.1.22"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0C0F4", "alignment_score": 804.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 402], "sequence": "MKIAVAGSGYVGLSLGVLLSLQNEVTIVDILPSKVDKINNGLSPIQDEYIEYYLKSKQLSIKATLDSKAAYKEAELVIIATPTNYNSRINYFDTQHVETVIKEVLSVNSHATLIIKSTIPIGFITEMRQKFQTDRIIFSPEFLRESKALYDNLYPSRIIVSCEENDSPKVKADAEKFALLLKSAAKKNNVPVLIMGASEAEAVKLFANTYLALRVAYFNELDTYAESRKLNSHMIIQGISYDDRIGMHYNNPSFGYGGYCLPKDTKQLLANYNNIPQTLIEAIVSSNNVRKSYIAKQIINVLKEQESPVKVVGVYRLIMKSNSDNFRESAIKDVIDILKSKDIKIIIYEPMLNKLESEDQSVLVNDLENFKKQANIIVTNRYDNELQDVKNKVYSRDIFGRD", "length": 402, "reference_go_mf": ["GO:0051287", "GO:0003979"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_613ff69dedff2ae8096b"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_931_2pth_assembly1", "enzyme_name": "aminoacyl-tRNA hydrolase", "ec": ["3.1.1.29"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0A7D1", "alignment_score": 386.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 194], "sequence": "MTIKLIVGLANPGAEYAATRHNAGAWFVDLLAERLRAPLREEAKFFGYTSRVTLGGEDVRLLVPTTFMNLSGKAVAAMASFFRINPDEILVAHDELDLPPGVAKFKLGGGHGGHNGLKDIISKLGNNPNFHRLRIGIGHPGDKNKVVGFVLGKPPVSEQKLIDEAIDEAARCTEMWFTDGLTKATNRLHAFKAQ", "length": 194, "reference_go_mf": ["GO:0004045", "GO:0000049"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_13b816b5f7e6cffd36e8"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_932_2tdt_assembly1", "enzyme_name": "2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase", "ec": ["2.3.1.117"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P56220", "alignment_score": 548.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 274], "sequence": "MQQLQNVIESAFERRADITPANVDTVTREAVNQVIGLLDSGALRVAEKIDGQWVTHQWLKKAVLLSFRINDNKVMDGAETRYYDKVPMKFADYDEARFQKEGFRVVPPATVRQGAFIARNTVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQANPTIIEDNCFIGARSEVVEGVIVEEGSVISMGVYLGQSTRIYDRETGEIHYGRVPAGSVVVSGNLPSKDGSYSLYCAVIVKKVDAKTRGKVGINELLRTID", "length": 274, "reference_go_mf": ["GO:0008666", "GO:0016779"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_0dc114aaa2c400a65fcf"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P56220", "alignment_score": 548.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 274], "sequence": "MQQLQNVIESAFERRADITPANVDTVTREAVNQVIGLLDSGALRVAEKIDGQWVTHQWLKKAVLLSFRINDNKVMDGAETRYYDKVPMKFADYDEARFQKEGFRVVPPATVRQGAFIARNTVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQANPTIIEDNCFIGARSEVVEGVIVEEGSVISMGVYLGQSTRIYDRETGEIHYGRVPAGSVVVSGNLPSKDGSYSLYCAVIVKKVDAKTRGKVGINELLRTID", "length": 274, "reference_go_mf": ["GO:0008666", "GO:0016779"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_0dc114aaa2c400a65fcf"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_934_3cla_assembly1", "enzyme_name": "chloramphenicol O-acetyltransferase", "ec": ["2.3.1.28"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00484", "alignment_score": 426.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 213], "sequence": "MNYTKFDVKNWVRREHFEFYRHRLPCGFSLTSKIDITTLKKSLDDSAYKFYPVMIYLIAQAVNQFDELRMAIKDDELIVWDSVDPQFTVFHQETETFSALSCPYSSDIDQFMVNYLSVMERYKSDTKLFPQGVTPENHLNISALPWVNFDSFNLNVANFTDYFAPIITMAKYQQEGDRLLLPLSVQVHHAVCDGFHVARFINRLQELCNSKLK", "length": 213, "reference_go_mf": ["GO:0008811"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_8e7cb4f472e327195952"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P00484", "alignment_score": 426.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 213], "sequence": "MNYTKFDVKNWVRREHFEFYRHRLPCGFSLTSKIDITTLKKSLDDSAYKFYPVMIYLIAQAVNQFDELRMAIKDDELIVWDSVDPQFTVFHQETETFSALSCPYSSDIDQFMVNYLSVMERYKSDTKLFPQGVTPENHLNISALPWVNFDSFNLNVANFTDYFAPIITMAKYQQEGDRLLLPLSVQVHHAVCDGFHVARFINRLQELCNSKLK", "length": 213, "reference_go_mf": ["GO:0008811"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_8e7cb4f472e327195952"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_935_3nos_assembly1", "enzyme_name": "nitric-oxide synthase", "ec": ["1.14.13.39"], "controls": [{"chain": "A", "status": "reference_overlength", "selected": {"accession": "P29474", "alignment_score": 784.5, "observed_coverage": 1.0, "aligned_identity": 0.9975, "canonical_span": [66, 480], "sequence": "MGNLKSVAQEPGPPCGLGLGLGLGLCGKQGPATPAPEPSRAPASLLPPAPEHSPPSSPLTQPPEGPKFPRVKNWEVGSITYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQGRPSPGPPAPEQLLSQARDFINQYYSSIKRSGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCRSAQEMFTYICNHIKYATNRGNLRSAITVFPQRCPGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDDPPELFLLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINVAVLHSYQLAKVTIVDHHAATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFRYQPDPWKGSAAKGTGITRKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQLGRLFRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGESFAAALMEMSGPYNSSPRPEQHKSYKIRFNSISCSDPLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYPHFCAFARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAQAAFQAACETFCVGEDAKAAARDIFSPKRSWKRQRYRLSAQAEGLQLLPGLIHVHRRKMFQATIRSVENLQSSKSTRATILVRLDTGGQEGLQYQPGDHIGVCPPNRPGLVEALLSRVEDPPAPTEPVAVEQLEKGSPGGPPPGWVRDPRLPPCTLRQALTFFLDITSPPSPQLLRLLSTLAEEPREQQELEALSQDPRRYEEWKWFRCPTLLEVLEQFPSVALPAPLLLTQLPLLQPRYYSVSSAPSTHPGEIHLTVAVLAYRTQDGLGPLHYGVCSTWLSQLKPGDPVPCFIRGAPSFRLPPDPSLPCILVGPGTGIAPFRGFWQERLHDIESKGLQPTPMTLVFGCRCSQLDHLYRDEVQNAQQRGVFGRVLTAFSREPDNPKTYVQDILRTELAAEVHRVLCLERGHMFVCGDVTMATNVLQTVQRILATEGDMELDEAGDVIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERQLRGAVPWAFDPPGSDTNSP", "length": 1203, "reference_go_mf": ["GO:0003785", "GO:0034618", "GO:0046870", "GO:0005516", "GO:0050660", "GO:0010181", "GO:0020037", "GO:0050661", "GO:0004517", "GO:0097110", "GO:0016175", "GO:0034617"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_936_3pca_assembly1", "enzyme_name": "protocatechuate 3,4-dioxygenase", "ec": ["1.13.11.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00437", "alignment_score": 459.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 237], "sequence": "MPAQDNSRFVIRDRNWHPKALTPDYKTSIARSPRQALVSIPQSISETTGPNFSHLGFGAHDHDLLLNFNNGGLPIGERIIVAGRVVDQYGKPVPNTLVEMWQANAGGRYRHKNDRYLAPLDPNFGGVGRCLTDSDGYYSFRTIKPGPYPWRNGPNDWRPAHIHFGISGPSIATKLITQLYFEGDPLIPMCPIVKSIANPEAVQQLIAKLDMNNANPMDCLAYRFDIVLRGQRKTHFENC", "length": 239, "reference_go_mf": ["GO:0008199", "GO:0018578"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_d6f6df64f1dd8f03e775"}, "alternative_alignments": [{"accession": "P00436", "alignment_score": 12.0, "observed_coverage": 0.02575107296137339, "aligned_identity": 1.0, "canonical_span": [182, 188], "length": 201, "reference_go_mf": ["GO:0008199", "GO:0018578"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_937_7odc_assembly1", "enzyme_name": "ornithine decarboxylase", "ec": ["4.1.1.17"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P00860", "alignment_score": 739.5, "observed_coverage": 1.0, "aligned_identity": 0.9974160206718347, "canonical_span": [1, 418], "sequence": "MSSFTKDEFDCHILDEGFTAKDILDQKINEVSSSDDKDAFYVADLGDILKKHLRWLKALPRVTPFYAVKCNDSRAIVSTLAAIGTGFDCASKTEIQLVQGLGVPAERVIYANPCKQVSQIKYAASNGVQMMTFDSEIELMKVARAHPKAKLVLRIATDDSKAVCRLSVKFGATLKTSRLLLERAKELNIDVIGVSFHVGSGCTDPETFVQAVSDARCVFDMATEVGFSMHLLDIGGGFPGSEDTKLKFEEITSVINPALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKTVWKEQPGSDDEDESNEQTFMYYVNDGVYGSFNCILYDHAHVKALLQKRPKPDEKYYSSSIWGPTCDGLDRIVERCNLPEMHVGDWMLFENMGAYTVAAASTFNGFQRPNIYYVMSRPMWQLMKQIQSHGFPPEVEEQDDGTLPMSCAQESGMDRHPAACASARINV", "length": 461, "reference_go_mf": ["GO:0042978", "GO:0004586", "GO:0042803"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_c7652638ffed18dbf9cc"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_93_1dqa_assembly1", "enzyme_name": "hydroxymethylglutaryl-CoA reductase (NADPH)", "ec": ["1.1.1.34"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P04035", "alignment_score": 815.0, "observed_coverage": 1.0, "aligned_identity": 0.9975550122249389, "canonical_span": [461, 870], "sequence": "MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASTLAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTADTSKVSLGLDENVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQTETESTLSLKNPITSPVVTQKKVPDNCCRREPMLVRNNQKCDSVEEETGINRERKVEVIKPLVAETDTPNRATFVVGNSSLLDTSSVLVTQEPEIELPREPRPNEECLQILGNAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSKKLSEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDEKEFQVPMATTEGCLVASTNRGCRAIGLGGGASSRVLADGMTRGPVVRLPRACDSAEVKAWLETSEGFAVIKEAFDSTSRFARLQKLHTSIAGRNLYIRFQSRSGDAMGMNMISKGTEKALSKLHEYFPEMQILAVSGNYCTDKKPAAINWIEGRGKSVVCEAVIPAKVVREVLKTTTEAMIEVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVKSHMIHNRSKINLQDLQGACTKKTA", "length": 888, "reference_go_mf": ["GO:0120225", "GO:0030695", "GO:0004420", "GO:0070402"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_53ca26e9a4eeb6dc5593"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P04035", "alignment_score": 807.0, "observed_coverage": 1.0, "aligned_identity": 0.9975308641975309, "canonical_span": [461, 866], "sequence": "MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASTLAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTADTSKVSLGLDENVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQTETESTLSLKNPITSPVVTQKKVPDNCCRREPMLVRNNQKCDSVEEETGINRERKVEVIKPLVAETDTPNRATFVVGNSSLLDTSSVLVTQEPEIELPREPRPNEECLQILGNAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSKKLSEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDEKEFQVPMATTEGCLVASTNRGCRAIGLGGGASSRVLADGMTRGPVVRLPRACDSAEVKAWLETSEGFAVIKEAFDSTSRFARLQKLHTSIAGRNLYIRFQSRSGDAMGMNMISKGTEKALSKLHEYFPEMQILAVSGNYCTDKKPAAINWIEGRGKSVVCEAVIPAKVVREVLKTTTEAMIEVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVKSHMIHNRSKINLQDLQGACTKKTA", "length": 888, "reference_go_mf": ["GO:0120225", "GO:0030695", "GO:0004420", "GO:0070402"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_53ca26e9a4eeb6dc5593"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_940_4h2h_assembly1", "enzyme_name": "4-hydroxyproline betaine 2-epimerase", "ec": ["5.1.1.22"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q0FPQ4", "alignment_score": 732.0, "observed_coverage": 0.9945652173913043, "aligned_identity": 1.0, "canonical_span": [1, 367], "sequence": "MKIAEIQLFQHDLPVVNGPYRIASGDVWSLTTTIVKIIAEDGTIGWGETCPVGPTYAEAHAGGALAALEVLASGLAGAEALPLPLHTRMDSLLCGHNYAKSALDIAVHDLWGKRLGVPVHELLGGALTDSVSSYYSLGVMEPDEAARQALEKQREGYSRLQVKLGARPIEIDIEAIRKVWEAVRGTGIALAADGNRGWTTRDALRFSRECPDIPFVMEQPCNSFEDLEAIRPLCHHALYMDEDGTSLNTVITAAATSLVDGFGMKVSRIGGLQHMRAFRDFCAARNLPHTCDDAWGGDIVSAACTHIASTVLPRLMEGAWLAQPYVAEHYDAENGVRIEGGRIRVPQGPGLGLTIDPERFGPPLFSA", "length": 367, "reference_go_mf": ["GO:0047661", "GO:0000287", "GO:0016855"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_7effec05c3728b23cfe5"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_941_3gdp_assembly2", "enzyme_name": "(R)-mandelonitrile lyase", "ec": ["4.1.2.10"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q945K2", "alignment_score": 1039.0, "observed_coverage": 1.0, "aligned_identity": 0.9980806142034548, "canonical_span": [27, 548], "sequence": "MEKSTMSAILLVLYIFVLHLQYSEVHSLATTSDHDFSYLSFAYDATDLELEGSYDYVIVGGGTSGCPLAATLSEKYKVLVLERGSLPTAYPNVLTADGFVYNLQQEDDGKTPVERFVSEDGIDNVRGRVLGGTSIINAGVYARANTSIYSASGVDWDMDLVNQTYEWVEDTIVYKPNSQSWQSVTKTAFLEAGVHPNHGFSLDHEEGTRITGSTFDNKGTRHAADELLNKGNSNNLRVGVHASVEKIIFSNAPGLTATGVIYRDSNGTPHQAFVRSKGEVIVSAGTIGTPQLLLLSGVGPESYLSSLNIPVVLSHPYVGQFLHDNPRNFINILPPNPIEPTIVTVLGISNDFYQCSFSSLPFTTPPFGFFPSASYPLPNSTFAHFASKVAGPLSYGSLTLKSSSNVRVSPNVKFNYYSNLTDLSHCVSGMKKIGELLSTDALKPYKVEDLPGVEGFNILGIPLPKDQTDDAAFETFCRESVASYWHYHGGCLVGKVLDGDFRVTGINALRVVDGSTFPYTPASHPQGFYLMLGRYVGIKILQERSASDLKILDSLKSAASLVL", "length": 563, "reference_go_mf": ["GO:0050660", "GO:0046593", "GO:0016614"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_47e66b57aa5673b2b19b"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_942_2oln_assembly1", "enzyme_name": "NikD", "ec": ["1.-.-.-"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q9X9P9", "alignment_score": 770.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [2, 387], "sequence": "MTESYDVVVVGGGPVGLATAWQVAERGHRVLVLERHTFFNENGGTSGAERHWRLQYTQEDLFRLTLETLPLWRALESRCERRLIHEIGSLWFGDTDVVTNEGQISGTAAMMDKLSVRYEWLKATDIERRFGFRGLPRDYEGFLQPDGGTIDVRGTLAALFTLAQAAGATLRAGETVTELVPDADGVSVTTDRGTYRAGKVVLACGPYTNDLLEPLGARLAYSVYEMAIAAYRQATPVTEAPFWFAFQQPTPQDTNLFYGFGHNPWAPGEFVRCGPDFEVDPLDHPSAATGVADRRQMDRLSGWLRDHLPTVDPDPVRTSTCLAVLPTDPERQFFLGTARDLMTHGEKLVVYGAGWAFKFVPLFGRICADLAVEDSTAYDISRLAPQSAL", "length": 389, "reference_go_mf": ["GO:0050660", "GO:0008115"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_1c6120bf5b7d4590b835"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_943_4njk_assembly1", "enzyme_name": "7-carboxy-7-deazaguanine synthase", "ec": ["4.3.99.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "A0A0H3KB22", "alignment_score": 418.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 210], "sequence": "MTYAVKEIFYTLQGEGANAGRPAVFCRFAGCNLWSGREEDRAQAVCRFCDTDFVGTDGENGGKFKDADALVATIAGLWPAGEAHRFVVCTGGEPMLQLDQPLVDALHAAGFGIAIETNGSLPVLESIDWICVSPKADAPLVVTKGNELKVVIPQDNQRLADYAKLDFEYFLVQPMDGPSRDLNTKLAIDWCKRHPQWRLSMQTHKYLNIP", "length": 210, "reference_go_mf": ["GO:0051539", "GO:0016840", "GO:0042802", "GO:0000287", "GO:0042803", "GO:1904047"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_138cffc416512a82b1bc"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_944_3fnl_assembly1", "enzyme_name": "Lactoperoxidase", "ec": ["1.11.1.7"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "A5JUY8", "alignment_score": 1155.0, "observed_coverage": 1.0, "aligned_identity": 0.9848484848484849, "canonical_span": [117, 712], "sequence": "MWVCLQLPVFLASVTLFEVAASDTIAQAASTTTISDAVSKVKIQVNKAFLDSRTRLKTTLSSEAPTTQQLSEYFKHAKGQTRTAIRNGQVWEESFKRLRRDTTLTNVTDPSLDLTALSWEVGCGAPVPLVKCDENSPYRTITGDCNNRRSPALGAANRALARWLPAEYEDGLALPFGWTQRKTRNGFRVPLAREVSNKIVGYLDEEGVLDQNRSLLFMQWGQIVDHDLDFAPETELGSNEHSKTQCEEYCIQGDNCFPIMFPKNDPKLKTQGKCMPFFRAGFVCPTPPYQSLAREQINAVTSFLDASLVYGSEPSLASRLRNLSSPLGLMAVNQEAWDHGLAYLPFNNKKPSPCEFINTTARVPCFLAGDFRASEQILLATAHTLLLREHNRLARELKKLNPHWNGEKLYQEARKILGAFIQIITFRDYLPIVLGSEMQKWIPPYQGYNNSVDPRISNVFTFAFRFGHMEVPSTVSRLDENYQPWGPEAELPLHTLFFNTWRIIKDGGIDPLTRGLLAKKSKLMNQDKMVTSELRNKLFQPTHKIHGFDLAAINLQRCRDHGMPGYNSWRGFCGLSQPKTLKGLQTVLKNKILAKKLMDLYKTPDNIDIWIGGNAEPMVERGRVGPLLACLLGRQFQQIRDGDRFWWENPGVFTEKQRDSLQKFSFSRLICDNTHITKVPLHAFQANNYPHDFVDCSTVDKLDLSPWASREN", "length": 712, "reference_go_mf": ["GO:0005509", "GO:0020037", "GO:0140825", "GO:0004601", "GO:0036393"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_e5061913d5f887c73cda"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_947_1u1z_assembly1", "enzyme_name": "3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ", "ec": ["4.2.1.59"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q9HXY7", "alignment_score": 249.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [2, 145], "sequence": "MMDINEIREYLPHRYPFLLVDRVVELDIEGKRIRAYKNVSINEPFFNGHFPEHPIMPGVLIIEAMAQAAGILGFKMLDVKPADGTLYYFVGSDKLRFRQPVLPGDQLQLHAKFISVKRSIWKFDCHATVDDKPVCSAEIICAERKL", "length": 146, "reference_go_mf": ["GO:0019171"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_b203704878b3f6a51913"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "Q9HXY7", "alignment_score": 264.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [2, 146], "sequence": "MMDINEIREYLPHRYPFLLVDRVVELDIEGKRIRAYKNVSINEPFFNGHFPEHPIMPGVLIIEAMAQAAGILGFKMLDVKPADGTLYYFVGSDKLRFRQPVLPGDQLQLHAKFISVKRSIWKFDCHATVDDKPVCSAEIICAERKL", "length": 146, "reference_go_mf": ["GO:0019171"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_b203704878b3f6a51913"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_948_1m3s_assembly2", "enzyme_name": "3-hexulose-6-phosphate isomerase", "ec": ["5.3.1.27"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P42404", "alignment_score": 352.0, "observed_coverage": 0.994475138121547, "aligned_identity": 1.0, "canonical_span": [0, 185], "sequence": "MKTTEYVAEILNELHNSAAYISNEEADQLADHILSSHQIFTAGAGRSGLMAKSFAMRLMHMGFNAHIVGEILTPPLAEGDLVIIGSGSGETKSLIHTAAKAKSLHGIVAALTINPESSIGKQADLIIRMPGSPKDQSNGSYKTIQPMGSLFEQTLLLFYDAVILKLMEKKGLDSETMFTHHANLE", "length": 185, "reference_go_mf": ["GO:0043800", "GO:0097367"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_c95e8701feaaf3e7d45f"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P42404", "alignment_score": 357.0, "observed_coverage": 0.994535519125683, "aligned_identity": 1.0, "canonical_span": [0, 185], "sequence": "MKTTEYVAEILNELHNSAAYISNEEADQLADHILSSHQIFTAGAGRSGLMAKSFAMRLMHMGFNAHIVGEILTPPLAEGDLVIIGSGSGETKSLIHTAAKAKSLHGIVAALTINPESSIGKQADLIIRMPGSPKDQSNGSYKTIQPMGSLFEQTLLLFYDAVILKLMEKKGLDSETMFTHHANLE", "length": 185, "reference_go_mf": ["GO:0043800", "GO:0097367"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_c95e8701feaaf3e7d45f"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_949_4xb6_assembly1", "enzyme_name": "alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase", "ec": ["4.7.1.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P16688", "alignment_score": 554.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 278], "sequence": "MANLSGYNFAYLDEQTKRMIRRAILKAVAIPGYQVPFGGREMPMPYGWGTGGIQLTASVIGESDVLKVIDQGADDTTNAVSIRNFFKRVTGVNTTERTDDATVIQTRHRIPETPLTEDQIIIFQVPIPEPLRFIEPRETETRTMHALEEYGVMQVKLYEDIARFGHIATTYAYPVKVNGRYVMDPSPIPKFDNPKMDMMPALQLFGAGREKRIYAVPPFTRVESLDFDDHPFTVQQWDEPCAICGSTHSYLDEVVLDDAGNRMFVCSDTDYCRQQSEAKNQ", "length": 281, "reference_go_mf": ["GO:0051539", "GO:0098848", "GO:0016829"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_72aca41a45d58896ad47"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_94_1wab_assembly1", "enzyme_name": "1-alkyl-2-acetylglycerophosphocholine esterase", "ec": ["3.1.1.47"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q29460", "alignment_score": 424.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [4, 216], "sequence": "MSGDENPASKPTPVQDVQGDGRWMSLHHRFVADSKDKEPEVVFIGDSLVQLMHQCEIWRELFSPLHALNFGIGGDSTQHVLWRLENGELEHIRPKIVVVWVGTNNHGHTAEQVTGGIKAIVQLVNERQPQARVVVLGLLPRGQHPNPLREKNRRVNELVRAALAGHPRAHFLDADPGFVHSDGTISHHDMYDYLHLSRLGYTPVCRALHSLLLRLLTQDQGQGGAPLPEPSP", "length": 232, "reference_go_mf": ["GO:0003847", "GO:0047179", "GO:0046982", "GO:0042803"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_a07334a7a634b879fc65"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_951_4mhx_assembly1", "enzyme_name": "N-sulfoglucosamine sulfohydrolase", "ec": ["3.10.1.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P51688", "alignment_score": 954.0, "observed_coverage": 0.995850622406639, "aligned_identity": 1.0, "canonical_span": [21, 502], "sequence": "MSCPVPACCALLLVLGLCRARPRNALLLLADDGGFESGAYNNSAIATPHLDALARRSLLFRNAFTSVSSCSPSRASLLTGLPQHQNGMYGLHQDVHHFNSFDKVRSLPLLLSQAGVRTGIIGKKHVGPETVYPFDFAYTEENGSVLQVGRNITRIKLLVRKFLQTQDDRPFFLYVAFHDPHRCGHSQPQYGTFCEKFGNGESGMGRIPDWTPQAYDPLDVLVPYFVPNTPAARADLAAQYTTVGRMDQGVGLVLQELRDAGVLNDTLVIFTSDNGIPFPSGRTNLYWPGTAEPLLVSSPEHPKRWGQVSEAYVSLLDLTPTILDWFSIPYPSYAIFGSKTIHLTGRSLLPALEAEPLWATVFGSQSHHEVTMSYPMRSVQHRHFRLVHNLNFKMPFPIDQDFYVSPTFQDLLNRTTAGQPTGWYKDLRHYYYRARWELYDRSRDPHETQNLATDPRFAQLLEMLRDQLAKWQWETHDPWVCAPDGVLEEKLSPQCQPLHNEL", "length": 502, "reference_go_mf": ["GO:0016250", "GO:0008484"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_39837e529c63ea9c0da0"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_952_2hw4_assembly1", "enzyme_name": "phosphohistidine phosphatase", "ec": ["3.9.1.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q9NRX4", "alignment_score": 210.5, "observed_coverage": 0.9482758620689655, "aligned_identity": 1.0, "canonical_span": [4, 122], "sequence": "MAVADLALIPDVDIDSDGVFKYVLIRVHSAPRSGAPAAESKEIVRGYKWAEYHADIYDKVSGDMQKQGCDCECLGGGRISHQSQDKKIHVYGYSMAYGPAQHAISTEKIKAKYPDYEVTWANDGY", "length": 125, "reference_go_mf": ["GO:0051015", "GO:0019855", "GO:0004857", "GO:0101006", "GO:0044325"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_2f6e0c09aa9ba2acd460"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_953_1deu_assembly1", "enzyme_name": "cathepsin X", "ec": ["3.4.18.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q9UBR2", "alignment_score": 547.0, "observed_coverage": 1.0, "aligned_identity": 0.9963636363636363, "canonical_span": [28, 303], "sequence": "MARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCEGGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWGERGWLRIVTSTYKDGKGARYNLAIEEHCTFGDPIV", "length": 303, "reference_go_mf": ["GO:0004180", "GO:0016807", "GO:0008234"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_a3f501dbf34ace44543f"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_954_3wql_assembly1", "enzyme_name": "isotuberculosinol synthase", "ec": ["3.1.7.9"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P9WJ61", "alignment_score": 562.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 296], "sequence": "MNLVSEKEFLDLPLVSVAEIVRCRGPKVSVFPFDGTRRWFHLECNPQYDDYQQAALRQSIRILKMLFEHGIETVISPIFSDDLLDRGDRYIVQALEGMALLANDEEILSFYKEHEVHVLFYGDYKKRLPSTAQGAAVVKSFDDLTISTSSNTEHRLCFGVFGNDAAESVAQFSISWNETHGKPPTRREIIEGYYGEYVDKADMFIGFGRFSTFDFPLLSSGKTSLYFTVAPSYYMTETTLRRILYDHIYLRHFRPKPDYSAMSADQLNVLRNRYRAQPDRVFGVGCVHDGIWFAEG", "length": 296, "reference_go_mf": ["GO:0062204", "GO:0016791", "GO:0016765"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_8ea48812b06b065143c0"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_956_2zr8_assembly1", "enzyme_name": "L-serine ammonia-lyase", "ec": ["4.3.1.17"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "O59791", "alignment_score": 638.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [4, 323], "sequence": "MSDNLVLPTYDDVASASERIKKFANKTPVLTSSTVNKEFVAEVFFKCENFQKMGAFKFRGALNALSQLNEAQRKAGVLTFSSGNHAQAIALSAKILGIPAKIIMPLDAPEAKVAATKGYGGQVIMYDRYKDDREKMAKEISEREGLTIIPPYDHPHVLAGQGTAAKELFEEVGPLDALFVCLGGGGLLSGSALAARHFAPNCEVYGVEPEAGNDGQQSFRKGSIVHIDTPKTIADGAQTQHLGNYTFSIIKEKVDDILTVSDEELIDCLKFYAARMKIVVEPTGCLSFAAARAMKEKLKNKRIGIIISGGNVDIERYAHFLSQ", "length": 323, "reference_go_mf": ["GO:0005524", "GO:0008721", "GO:0003941", "GO:0000287", "GO:0042803", "GO:0030170", "GO:0030378"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_cb404f718b8dc5730788"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_957_1tkk_assembly1", "enzyme_name": "L-Ala-D/L-Glu epimerase", "ec": ["5.1.1.20"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "O34508", "alignment_score": 718.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 359], "sequence": "MKIIRIETSRIAVPLTKPFKTALRTVYTAESVIVRITYDSGAVGWGEAPPTLVITGDSMDSIESAIHHVLKPALLGKSLAGYEAILHDIQHLLTGNMSAKAAVEMALYDGWAQMCGLPLYQMLGGYRDTLETDYTVSVNSPEEMAADAENYLKQGFQTLKIKVGKDDIATDIARIQEIRKRVGSAVKLRLDANQGWRPKEAVTAIRKMEDAGLGIELVEQPVHKDDLAGLKKVTDATDTPIMADESVFTPRQAFEVLQTRSADLINIKLMKAGGISGAEKINAMAEACGVECMVGSMIETKLGITAAAHFAASKRNITRFDFDAPLMLKTDVFNGGITYSGSTISMPGKPGLGIIGAALLKGEKEQ", "length": 366, "reference_go_mf": ["GO:0103031", "GO:0000287", "GO:0016854"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_4db80cd1a2bab88f04df"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_958_2p8b_assembly1", "enzyme_name": "N-succinylamino acid racemase (type 2)", "ec": ["5.1.1.-"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q81IL5", "alignment_score": 738.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 369], "sequence": "MKITAIHLYAIRLPLRNPFVISYGSYSDMPSIIVKMETDEGIIGYGEGVADDHVTGESWESTFHTLKHTLTPALIGQNPMNIEKIHDMMDNTIYGVPTAKAAIDIACFDIMGKKLNQPVYQLIGGRYHEEFPVTHVLSIADPENMAEEAASMIQKGYQSFKMKVGTNVKEDVKRIEAVRERVGNDIAIRVDVNQGWKNSANTLTALRSLGHLNIDWIEQPVIADDIDAMAHIRSKTDLPLMIDEGLKSSREMRQIIKLEAADKVNIKLMKCGGIYPAVKLAHQAEMAGIECQVGSMVESSVASSAGFHVAFSKKIITSVELTGPLKFTKDIGNLHYDVPFIRLNEKPGLGIEINEDTLQELTVFQDIVR", "length": 369, "reference_go_mf": ["GO:0047661", "GO:0000287", "GO:0016854"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_7fd5eda72a12ee20aa6a"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_959_3dg6_assembly1", "enzyme_name": "muconate cycloisomerase (anti)", "ec": ["5.5.1.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "A0QTN8", "alignment_score": 732.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 366], "sequence": "MKIVAIGAIPFSIPYTKPLRFASGEVHAAEHVLVRVHTDDGIVGVAEAPPRPFTYGETQTGIVAVIEQYFAPALIGLTLTEREVAHTRMARTVGNPTAKAAIDMAMWDALGQSLRLSVSEMLGGYTDRMRVSHMLGFDDPVKMVAEAERIRETYGINTFKVKVGRRPVQLDTAVVRALRERFGDAIELYVDGNRGWSAAESLRAMREMADLDLLFAEELCPADDVLSRRRLVGQLDMPFIADESVPTPADVTREVLGGSATAISIKTARTGFTGSTRVHHLAEGLGLDMVMGNQIDGQIGTACTVSFGTAFERTSRHAGELSNFLDMSDDLLTVPLQISDGQLHRRPGPGLGIEIDPDKLAHYRTDN", "length": 367, "reference_go_mf": ["GO:0000287", "GO:0016854"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_06e4cb1df7d3bb74d292"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_95_1fui_assembly1", "enzyme_name": "L-fucose isomerase", "ec": ["5.3.1.25"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P69922", "alignment_score": 1182.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 591], "sequence": "MKKISLPKIGIRPVIDGRRMGVRESLEEQTMNMAKATAALLTEKLRHACGAAVECVISDTCIAGMAEAAACEEKFSSQNVGLTITVTPCWCYGSETIDMDPTRPKAIWGFNGTERPGAVYLAAALAAHSQKGIPAFSIYGHDVQDADDTSIPADVEEKLLRFARAGLAVASMKGKSYLSLGGVSMGIAGSIVDHNFFESWLGMKVQAVDMTELRRRIDQKIYDEAELEMALAWADKNFRYGEDENNKQYQRNAEQSRAVLRESLLMAMCIRDMMQGNSKLADIGRVEESLGYNAIAAGFQGQRHWTDQYPNGDTAEAILNSSFDWNGVREPFVVATENDSLNGVAMLMGHQLTGTAQVFADVRTYWSPEAIERVTGHKLDGLAEHGIIHLINSGSAALDGSCKQRDSEGNPTMKPHWEISQQEADACLAATEWCPAIHEYFRGGGYSSRFLTEGGVPFTMTRVNIIKGLGPVLQIAEGWSVELPKDVHDILNKRTNSTWPTTWFAPRLTGKGPFTDVYSVMANWGANHGVLTIGHVGADFITLASMLRIPVCMHNVEETKVYRPSAWAAHGMDIEGQDYRACQNYGPLYKR", "length": 591, "reference_go_mf": ["GO:0008790", "GO:0042802", "GO:0008736", "GO:0030145"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_185762f51664018f3c73"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_960_2qjj_assembly1", "enzyme_name": "mannonate dehydratase", "ec": ["4.2.1.8"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "A4XF23", "alignment_score": 804.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 402], "sequence": "MKITAARVIITCPGRNFVTLKIETDQGVYGIGDATLNGRELSVVAYLQEHVAPCLIGMDPRRIEDIWQYVYRGAYWRRGPVTMRAIAAVDMALWDIKAKMAGMPLYQLLGGRSRDGIMVYGHANGSDIAETVEAVGHYIDMGYKAIRAQTGVPGIKDAYGVGRGKLYYEPADASLPSVTGWDTRKALNYVPKLFEELRKTYGFDHHLLHDGHHRYTPQEAANLGKMLEPYQLFWLEDCTPAENQEAFRLVRQHTVTPLAVGEIFNTIWDAKDLIQNQLIDYIRATVVGAGGLTHLRRIADLASLYQVRTGCHGATDLSPVTMGCALHFDTWVPNFGIQEYMRHTEETDAVFPHDYWFEKGELFVGETPGHGVDIDEELAAKYPYKPAYLPVARLEDGTMWNW", "length": 402, "reference_go_mf": ["GO:0000287", "GO:0008927"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_c9dc4463851be7f50b83"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_961_2hxt_assembly1", "enzyme_name": "L-fuconate dehydratase", "ec": ["4.2.1.68"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q8P3K2", "alignment_score": 868.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 435], "sequence": "MRTIIALETHDVRFPTSRELDGSDAMNPDPDYSAAYVVLRTDGAEDLAGYGLVFTIGRGNDVQTAAVAALAEHVVGLSVDKVIADLGAFARRLTNDSQLRWLGPEKGVMHMAIGAVINAAWDLAARAANKPLWRFIAELTPEQLVDTIDFRYLSDALTRDEALAILRDAQPQRAARTATLIEQGYPAYTTSPGWLGYSDEKLVRLAKEAVADGFRTIKLKVGANVQDDIRRCRLARAAIGPDIAMAVDANQRWDVGPAIDWMRQLAEFDIAWIEEPTSPDDVLGHAAIRQGITPVPVSTGEHTQNRVVFKQLLQAGAVDLIQIDAARVGGVNENLAILLLAAKFGVRVFPHAGGVGLCELVQHLAMADFVAITGKMEDRAIEFVDHLHQHFLDPVRIQHGRYLAPEVPGFSAEMHPASIAEFSYPDGRFWVEDLAASKAKA", "length": 441, "reference_go_mf": ["GO:0016836", "GO:0050023", "GO:0000287"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_e8cf07d1a9f1d212cbd1"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_962_3d47_assembly1", "enzyme_name": "L-rhamnonate dehydratase", "ec": ["4.2.1.90"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q8ZNF9", "alignment_score": 810.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 405], "sequence": "MENIMTLPKIKHVRAWFIGGATAEKGAGGGDYHDQGGNHWIDDHIATPMSKYRDYEQSRQSFGINVLGTLIVEVEAENRQTGFAVSTAGEMGCFIVEKHLNRFIEGKCVSDIKLIHDQMLGATMYYSGSGGLVMNTISCVDLALWDLFGKVVGLPVYKLLGGAVRDEIQFYATGARPDLAKEMGFIGGKMPTHWGPHDGDAGIRKDAAMVADMREKCGPDFWLMLDCWMSQDVNYATKLAHACAPFNLKWIEECLPPQQYEGYRELKRNAPAGMMVTSGEHHGTLQSFRTLAETGIDIMQPDVGWCGGLTTLVEIAALAKSRGQLVVPHGSSVYSHHAVITFTNTPFSEFLMTSPDCSTLRPQFDPILLDEPVPVNGRIHKSVLDKPGFGVELNRDCHLKRPYSH", "length": 405, "reference_go_mf": ["GO:0016836", "GO:0050032", "GO:0000287"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_612614c6e5248381abd4"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_963_4eay_assembly1", "enzyme_name": "mannonate dehydratase (uxuA)", "ec": ["4.2.1.8"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P24215", "alignment_score": 786.0, "observed_coverage": 0.9949367088607595, "aligned_identity": 1.0, "canonical_span": [0, 393], "sequence": "MEQTWRWYGPNDPVSLADVRQAGATGVVTALHHIPNGEVWSVEEILKRKAIIEDAGLVWSVVESVPIHEDIKTHTGNYEQWIANYQQTLRNLAQCGIRTVCYNFMPVLDWTRTDLEYVLPDGSKALRFDQIEFAAFEMHILKRPGAEADYTEEEIAQAAERFATMSDEDKARLTRNIIAGLPGAEEGYTLDQFRKHLELYKDIDKAKLRENFAVFLKAIIPVAEEVGVRMAVHPDDPPRPILGLPRIVSTIEDMQWMVDTVNSMANGFTMCTGSYGVRADNDLVDMIKQFGPRIYFTHLRSTMREDNPKTFHEAAHLNGDVDMYEVVKAIVEEEHRRKAEGKEDLIPMRPDHGHQMLDDLKKKTNPGYSAIGRLKGLAEVRGVELAIQRAFFSR", "length": 394, "reference_go_mf": ["GO:0008198", "GO:0030145", "GO:0008927"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_572709371cd10265bbb0"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_964_1g2i_assembly1", "enzyme_name": "intracellular protease", "ec": ["3.4.22.-"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "O59413", "alignment_score": 306.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 166], "sequence": "MKVLFLTANEFEDVELIYPYHRLKEEGHEVYIASFERGTITGKHGYSVKVDLTFDKVNPEEFDALVLPGGRAPERVRLNEKAVSIARKMFSEGKPVASICHGPQILISAGVLRGRKGTSYPGIKDDMINAGVEWVDAEVVVDGNWVSSRVPADLYAWMREFVKLLK", "length": 166, "reference_go_mf": ["GO:0036524"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_700246216325f472d315"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "O59413", "alignment_score": 306.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 166], "sequence": "MKVLFLTANEFEDVELIYPYHRLKEEGHEVYIASFERGTITGKHGYSVKVDLTFDKVNPEEFDALVLPGGRAPERVRLNEKAVSIARKMFSEGKPVASICHGPQILISAGVLRGRKGTSYPGIKDDMINAGVEWVDAEVVVDGNWVSSRVPADLYAWMREFVKLLK", "length": 166, "reference_go_mf": ["GO:0036524"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_700246216325f472d315"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_965_5vsm_assembly1", "enzyme_name": "Viperin", "ec": ["2.-.-.-"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q8CBB9", "alignment_score": 508.5, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [73, 335], "sequence": "MGMLVPTALAARLLSLFQQQLGSLWSGLAILFCWLRIALGWLDPGKEQPQVRGEPEDTQETQEDGNSTQPTTPVSVNYHFTRQCNYKCGFCFHTAKTSFVLPLEEAKRGLLLLKQAGLEKINFSGGEPFLQDRGEYLGKLVRFCKEELALPSVSIVSNGSLIRERWFKDYGEYLDILAISCDSFDEQVNALIGRGQGKKNHVENLQKLRRWCRDYKVAFKINSVINRFNVDEDMNEHIKALSPVRWKVFQCLLIEGENSGEDALREAERFLISNEEFETFLERHKEVSCLVPESNQKMKDSYLILDEYMRFLNCTGGRKDPSKSILDVGVEEAIKFSGFDEKMFLKRGGKYVWSKADLKLDW", "length": 362, "reference_go_mf": ["GO:0051539", "GO:0003824"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_a4420bbab055fe32ab2c"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_966_4x9e_assembly1", "enzyme_name": "dGTPase", "ec": ["3.1.5.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P15723", "alignment_score": 984.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 505], "sequence": "MAQIDFRKKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPAIRRLQQKTQVFPLERNAAVRTRLTHSMEVQQVGRYIAKEILSRLKELKLLEAYGLDELTGPFESIVEMSCLMHDIGNPPFGHFGEAAINDWFRQRLHPEDAESQPLTDDRCSVAALRLRDGEEPLNELRRKIRQDLCHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWWRGETPETHHYLMKKPGYYLSEEAYIARLRKELNLALYSRFPLTWIMEAADDISYCVADLEDAVEKRIFTVEQLYHHLHEAWGQHEKGSLFSLVVENAWEKSRSNSLSRSTEDQFFMYLRVNTLNKLVPYAAQRFIDNLPAIFAGTFNHALLEDASECSDLLKLYKNVAVKHVFSHPDVERLELQGYRVISGLLEIYRPLLSLSLSDFTELVEKERVKRFPIESRLFHKLSTRHRLAYVEAVSKLPSDSPEFPLWEYYYRCRLLQDYISGMTDLYAWDEYRRLMAVEQ", "length": 505, "reference_go_mf": ["GO:0050897", "GO:0008832", "GO:0003924", "GO:0042802", "GO:0000287", "GO:0030145", "GO:0003697"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_80a3841ec21cd26ac65f"}, "alternative_alignments": []}, {"chain": "B", "status": "assigned", "selected": {"accession": "P15723", "alignment_score": 969.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 505], "sequence": "MAQIDFRKKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPAIRRLQQKTQVFPLERNAAVRTRLTHSMEVQQVGRYIAKEILSRLKELKLLEAYGLDELTGPFESIVEMSCLMHDIGNPPFGHFGEAAINDWFRQRLHPEDAESQPLTDDRCSVAALRLRDGEEPLNELRRKIRQDLCHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWWRGETPETHHYLMKKPGYYLSEEAYIARLRKELNLALYSRFPLTWIMEAADDISYCVADLEDAVEKRIFTVEQLYHHLHEAWGQHEKGSLFSLVVENAWEKSRSNSLSRSTEDQFFMYLRVNTLNKLVPYAAQRFIDNLPAIFAGTFNHALLEDASECSDLLKLYKNVAVKHVFSHPDVERLELQGYRVISGLLEIYRPLLSLSLSDFTELVEKERVKRFPIESRLFHKLSTRHRLAYVEAVSKLPSDSPEFPLWEYYYRCRLLQDYISGMTDLYAWDEYRRLMAVEQ", "length": 505, "reference_go_mf": ["GO:0050897", "GO:0008832", "GO:0003924", "GO:0042802", "GO:0000287", "GO:0030145", "GO:0003697"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_80a3841ec21cd26ac65f"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_967_3uxj_assembly1", "enzyme_name": "NADPH-dependent 7-cyano-7-deazaguanine reductase", "ec": ["1.7.1.13"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q9KTK0", "alignment_score": 487.0, "observed_coverage": 0.9883268482490273, "aligned_identity": 0.9960629921259843, "canonical_span": [20, 277], "sequence": "MSKYSDAKELASLTLGKKTEYANQYDPSLLQPVPRSLNRNDLHLSATLPFQGCDIWTLYELSWLNQKGLPQVAIGEVSIPATSANLIESKSFKLYLNSYNQTRFASWDEVQTRLVHDLSACAGETVTVNVKSLNEYTAEPIVTMQGECIDDQDIEIANYEFDDALLQGAAQGEEVSEVLHSHLLKSNCLITNQPDWGSVEIAYHGAKMNREALLRYLVSFREHNEFHEQCVERIFTDIMRYCQPQSLTVYARYTRRGGLDINPFRSSHQSAPNHNQRMARQ", "length": 281, "reference_go_mf": ["GO:0033739"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_95eceacd989fee8cd53d"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_969_4dgk_assembly1", "enzyme_name": "Phytoene desaturase (lycopene-forming)", "ec": ["1.3.99.31"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P21685", "alignment_score": 728.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 492], "sequence": "MKPTTVIGAGFGGLALAIRLQAAGIPVLLLEQRDKPGGRAYVYEDQGFTFDAGPTVITDPSAIEELFALAGKQLKEYVELLPVTPFYRLCWESGKVFNYDNDQTRLEAQIQQFNPRDVEGYRQFLDYSRAVFKEGYLKLGTVPFLSFRDMLRAAPQLAKLQAWRSVYSKVASYIEDEHLRQAFSFHSLLVGGNPFATSSIYTLIHALEREWGVWFPRGGTGALVQGMIKLFQDLGGEVVLNARVSHMETTGNKIEAVHLEDGRRFLTQAVASNADVVHTYRDLLSQHPAAVKQSNKLQTKRMSNSLFVLYFGLNHHHDQLAHHTVCFGPRYRELIDEIFNHDGLAEDFSLYLHAPCVTDSSLAPEGCGSYYVLAPVPHLGTANLDWTVEGPKLRDRIFAYLEQHYMPGLRSQLVTHRMFTPFDFRDQLNAYHGSAFSVEPVLTQSAWFRPHNRDKTITNLYLVGAGTHPGAGIPGVIGSAKATAGLMLEDLI", "length": 492, "reference_go_mf": ["GO:0071949", "GO:0016627"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_9d15b3b113a0c8d70ccf"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_96_1chm_assembly1", "enzyme_name": "creatinase", "ec": ["3.5.3.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P38488", "alignment_score": 802.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 402], "sequence": "MQMPKTLRIRNGDKVRSTFSAQEYANRQARLRAHLAAENIDAAIFTSYHNINYYSDFLYCSFGRPYALVVTEDDVISISANIDGGQPWRRTVGTDNIVYTDWQRDNYFAAIQQALPKARRIGIEHDHLNLQNRDKLAARYPDAELVDVAAACMRMRMIKSAEEHVMIRHGARIADIGGAAVVEALGDQVPEYEVALHATQAMVRAIADTFEDVELMDTWTWFQSGINTDGAHNPVTTRKVNKGDILSLNCFPMIAGYYTALERTLFLDHCSDDHLRLWQVNVEVHEAGLKLIKPGARCSDIARELNEIFLKHDVLQYRTFGYGHSFGTLSHYYGREAGLELREDIDTVLEPGMVVSMEPMIMLPEGLPGAGGYREHDILIVNENGAENITKFPYGPEKNIIRK", "length": 403, "reference_go_mf": ["GO:0016980"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_05691b7500445f0bf72b"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_970_3vmt_assembly1", "enzyme_name": "Peptidoglycan glycosyltransferase", "ec": ["2.4.1.129"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q99T05", "alignment_score": 435.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [40, 269], "sequence": "MKRSDRYSNSNEHFEHMKHEPHYNTYYQPVGKPPKKKKSKRILLKILLTILIIIALFIGIMYFLSTRDNVDELRKIENKSSFVSADNMPEYVKGAFISMEDERFYNHHGFDLKGTTRALFSTISDRDVQGGSTITQQVVKNYFYDNDRSFTRKVKELFVAHRVEKQYNKNEILSFYLNNIYFGDNQYTLEGAANHYFGTTVNKNSTTMSHITVLQSAILASKVNAPSVYNINNMSENFTQRVSTNLEKMKQQNYINETQYQQAMSQLNR", "length": 269, "reference_go_mf": ["GO:0008955"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_e44ae0a86de02287573b"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_971_2de2_assembly1", "enzyme_name": "2'-hydroxybiphenyl-2-sulfinate desulfinase", "ec": ["3.13.1.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P54997", "alignment_score": 694.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [18, 365], "sequence": "MTSRVDPANPGSELDSAIRDTLTYSNCPVPNALLTASESGFLDAAGIELDVLSGQQGTVHFTYDQPAYTRFGGEIPPLLSEGLRAPGRTRLLGITPLLGRQGFFVRDDSPITAAADLAGRRIGVSASAIRILRGQLGDYLELDPWRQTLVALGSWEARALLHTLEHGELGVDDVELVPISSPGVDVPAEQLEESATVKGADLFPDVARGQAAVLASGDVDALYSWLPWAGELQATGARPVVDLGLDERNAYASVWTVSSGLVRQRPGLVQRLVDAAVDAGLWARDHSDAVTSLHAANLGVSTGAVGQGFGADFQQRLVPRLDHDALALLERTQQFLLTNNLLQEPVALDQWAAPEFLNNSLNRHR", "length": 365, "reference_go_mf": ["GO:0018740"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_e10fddaee42c1a485816"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_972_2vz9_assembly1", "enzyme_name": "3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase", "ec": ["4.2.1.59"], "controls": [{"chain": "A", "status": "reference_overlength", "selected": {"accession": "A5YV76", "alignment_score": 4132.0, "observed_coverage": 1.0, "aligned_identity": 0.9995194617972128, "canonical_span": [0, 2113], "sequence": "MEEVVIAGMSGKLPESENLEEFWANLIGGVDMVTADDRRWKAGLYGLPRRMGKLKDLSRFDASFFGVHSKQANTMDPQLRMLLEVTYEAIVDGGINPASLRGTSTGVWVGVSSSDASEALSRDPETLVGYSMIGCQRAMMANRLSFFFDFKGPSITIDTACSSSLLALQSAYQAIRGGECSAAVVGGLNVLLKPNSSLQFMKLGMLSQDGTCRSFDAEGTGYCRAEAVVAVLLTKKSLARRVYATILNAGTNTDGSKEQGVTFPSGDVQEQLIRSLYAPAGPDPESLEYIEAHGTGTKVGDPQELNGIVNALCATRREPLLIGSTKSNMGHPEPASGVAALIKVLLSLEHGVWAPNLHYHTPNPEIPALQDGRLQVVDRPLPIRGGNVGINSFGFGGSNVHVILQPNSRPAPPPAQHAALPRLLQASGRTLEAVQTLLEQGLRHSRDLAFVGMLNEIAAVSPVAMPFRGYAVLGGEAGSQEVQQVPGSKRPVWFICSGMGAQWQGMGLSLMRLDRFRDSILRSDQALKPLGLRVSDLLLSTDEAVLDDIVSSFVSLTSIQIALIDLLTSLGLQPDGIIGHSLGEVACGYADGCLTQEEAVLSSYWRGYCIKEANVLPGAMAAVGLSWEECKQRCPPGIVPACHNSKDTVTISGPQAAMSEFLQQLKREDVFVKEVRTGGIAFHSYFMESIAPTLLRQLRKVILDPKPRSKRWLSTSIPEAQWQGSLARTFSAEYSVNNLVSPVLFQEALQHVPAHAVVVEIAPHALLQAVLKRSLESSCTIIPLMKKDHRDNLEFFLSNVGRLHLAGVSVNPNGLFPPVEFPAPRGTPLISPHXKWDHSQAWDVPSAADFPSGSSCSSVAVYKFDVSPESPDHYLVDHCIDGRVLFPGTGYLWLTWKTLARALSQNLEETPVVFEDVTLHQATILPKTGTVSLEVRLLEASHAFEVSDSNGSLIASGKVYQWESPDPKLFDTRAAVDPADSTAEFRLSQGDVYKDLRLRGYDYGPFFQLVLESDLEGNRGRLQWNDSWVSFLDAMLHMSILAPGQLGLYLPTRFTSIRIDPVTHRQKLYTLQDTTQAADVVVDRNLNTVVAGGALFLGAHSSVAPRRPQEHLKPILEKFCFTPHVESGCLAGNTALQEELQLCRGLAQALQTKVAQQGLKMVVPGLDGAQAPREAPQQSLPRLLAAACQLQLNGNLQLELGQVLAQERPLLCDDPLLSGLLDAPALKACVDTALENMASPKMKVVEVLAGDGQLYSRIPALLNTQPVMDLDYTATDRNPQALEAAQAKLEQLHVTQGQWDPANPAPGSLGKADLLVCNCALATLGDPAVAVGNMAATLKEGGFLLLHTLLAGHPLGEMVGFLTSPEQGGRHLLSQDQWESLFAGASLHLVALKRSFYGSVLFLCRQQTPQDSPVFLSVEDTSFRWVDSLKDILADASSRPVWLMAVGCSTSGVVGMVNCLRKEPGGHRIRCVLVSNLSSTSPAPEMHPSSSELQKVLQGDLVMNVYRDGAWGAFRHFPLEQDRPEKQTEHAFVNVLSRGDLSSIRWVCSPLHYALPASCQDRLCSVYYTSLNFRDVMLATGKLSPDSIPGKWLTRDCMLGMEFSGRDASGRRVMGMVPAEGLATSVLLLQHATWEVPSTWTLEEAASVPIVYTTAYYSLVVRGRMQPGESVLIHSGSGGVGQAAIAIALSRGCRVFTTVGSAEKRAYLQARFPQLDETCFANSRDTSFEQHVLRHTAGKGVDLVLNSLAEEKLQASVRCLAQHGRFLEIGKFDLSNNHALGMAVFLKNVTFHGILLDSLFEEGGATWQEVSELLKAGIQEGVVQPLKCTVFPRTKVEAAFRYMAQGKHIGKVVIQVREEEQGPAPRGLPPIALTGLSKTFCPPHKSYVITGGLGGFGLQLAQWLRLRGAQKLVLTSRSGIRTGYQARQVREWRRQGVQVLVSTSNASSLDGARSLITEATQLGPVGGVFNLAMVLRDAVLENQTPEFFQDVSKPKYSGTANLDRVTREACPELDYFVIFSSVSCGRGNAGQANYGFANSAMERICEKRRHDGLPGLAVQWGAIGDVGVVLETMGTNDTVIGGTLPQRIASCLEVLDLFLSQPHPVLSSFVLAEKKAAAPRDGSSQKDLVKAVAHILGIRDVASINPDSTLVDLGLDSLMGVEVRQILEREHDLVLSMREVRQLSLRKLQELSSKTSTDADPATPTSHEDSPVRQQATLNLSTLLVNPEGPTLTRLNSVQSAERPLFLVHPIEGSITVFHGLAAKLSIPTYGLQCTGAAPLDSIQSLASYYIECIRQVQPEGPYRIAGYSYGACVAFEMCSQLQAQQSATPGNHSLFLFDGSHTFVLAYTQSVRAKMTPGCEAEAEAKAMYFFVQQFTDMEQGKVLEALIPLQGLEARVAATVDLITQSHAGLDRHALSFAARSFYQKLRAAENYWPQATYHGNVTLLRAKTGGAYGEDLGADYNLSQVCDGKVSVHVIEGDHRTLLEGSGLESILSIIHSCLAEPRVSVREG", "length": 2512, "reference_go_mf": ["GO:0019171", "GO:0004316", "GO:0004315", "GO:0004313", "GO:0004314", "GO:0141148", "GO:0004312", "GO:0016297", "GO:0031177", "GO:0036094"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_973_3x0y_assembly1", "enzyme_name": "DszC protein", "ec": ["1.14.14.21"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "A0A0C6DRW4", "alignment_score": 804.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [15, 417], "sequence": "MTLSPEKQHVRPRDAADNDPVAVARGLAEKWRATAVERDRAGGSATAEREDLRASGLLSLLVPREYGGWGADWPTAIEVVREIAAADGSLGHLFGYHLTNAPMIELIGSQEQEEHLYTQIAQNNWWTGNASSENNSHVLDWKVRATPTEDGGYVLNGTKHFCSGAKGSDLLFVFGVVQDDSPQQGAIIAAAIPTSRAGVTPNDDWAAIGMRQTDSGSTDFHNVKVEPDEVLGAPNAFVLAFIQSERGSLFAPIAQLIFANVYLGIAHGALDAAREYTRTQARPWTPAGIQQATEDPYTIRSYGEFTIALQGADAAAREAAHLLQTVWDKGDALTPEDRGELMVKVSGVKALATNAALNISSGVFEVIGARGTHPRYGFDRFWRNVRTHSLHDPVSYKIADVGKHTLNGQYPIPGFTS", "length": 417, "reference_go_mf": ["GO:0008470", "GO:0018640", "GO:0050660"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_20dae6213b93c88bbba2"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_974_4piv_assembly1", "enzyme_name": "fatty acid synthase - \u03b2-ketoreductase (KR)", "ec": ["2.3.1.85"], "controls": [{"chain": "A", "status": "reference_overlength", "selected": {"accession": "P49327", "alignment_score": 990.0, "observed_coverage": 0.9983606557377049, "aligned_identity": 0.9983579638752053, "canonical_span": [1109, 2113], "sequence": "MEEVVIAGMSGKLPESENLQEFWDNLIGGVDMVTDDDRRWKAGLYGLPRRSGKLKDLSRFDASFFGVHPKQAHTMDPQLRLLLEVTYEAIVDGGINPDSLRGTHTGVWVGVSGSETSEALSRDPETLVGYSMVGCQRAMMANRLSFFFDFRGPSIALDTACSSSLMALQNAYQAIHSGQCPAAIVGGINVLLKPNTSVQFLRLGMLSPEGTCKAFDTAGNGYCRSEGVVAVLLTKKSLARRVYATILNAGTNTDGFKEQGVTFPSGDIQEQLIRSLYQSAGVAPESFEYIEAHGTGTKVGDPQELNGITRALCATRQEPLLIGSTKSNMGHPEPASGLAALAKVLLSLEHGLWAPNLHFHSPNPEIPALLDGRLQVVDQPLPVRGGNVGINSFGFGGSNVHIILRPNTQPPPAPAPHATLPRLLRASGRTPEAVQKLLEQGLRHSQDLAFLSMLNDIAAVPATAMPFRGYAVLGGERGGPEVQQVPAGERPLWFICSGMGTQWRGMGLSLMRLDRFRDSILRSDEAVKPFGLKVSQLLLSTDESTFDDIVHSFVSLTAIQIGLIDLLSCMGLRPDGIVGHSLGEVACGYADGCLSQEEAVLAAYWRGQCIKEAHLPPGAMAAVGLSWEECKQRCPPGVVPACHNSKDTVTISGPQAPVFEFVEQLRKEGVFAKEVRTGGMAFHSYFMEAIAPPLLQELKKVIREPKPRSARWLSTSIPEAQWHSSLARTSSAEYNVNNLVSPVLFQEALWHVPEHAVVLEIAPHALLQAVLKRGLKPSCTIIPLMKKDHRDNLEFFLAGIGRLHLSGIDANPNALFPPVEFPAPRGTPLISPLIKWDHSLAWDVPAAEDFPNGSGSPSAAIYNIDTSSESPDHYLVDHTLDGRVLFPATGYLSIVWKTLARALGLGVEQLPVVFEDVVLHQATILPKTGTVSLEVRLLEASRAFEVSENGNLVVSGKVYQWDDPDPRLFDHPESPTPNPTEPLFLAQAEVYKELRLRGYDYGPHFQGILEASLEGDSGRLLWKDNWVSFMDTMLQMSILGSAKHGLYLPTRVTAIHIDPATHRQKLYTLQDKAQVADVVVSRWLRVTVAGGVHISGLHTESAPRRQQEQQVPILEKFCFTPHTEEGCLSERAALQEELQLCKGLVQALQTKVTQQGLKMVVPGLDGAQIPRDPSQQELPRLLSAACRLQLNGNLQLELAQVLAQERPKLPEDPLLSGLLDSPALKACLDTAVENMPSLKMKVVEVLAGHGHLYSRIPGLLSPHPLLQLSYTATDRHPQALEAAQAELQQHDVAQGQWDPADPAPSALGSADLLVCNCAVAALGDPASALSNMVAALREGGFLLLHTLLRGHPLGDIVAFLTSTEPQYGQGILSQDAWESLFSRVSLRLVGLKKSFYGSTLFLCRRPTPQDSPIFLPVDDTSFRWVESLKGILADEDSSRPVWLKAINCATSGVVGLVNCLRREPGGNRLRCVLLSNLSSTSHVPEVDPGSAELQKVLQGDLVMNVYRDGAWGAFRHFLLEEDKPEEPTAHAFVSTLTRGDLSSIRWVCSSLRHAQPTCPGAQLCTVYYASLNFRDIMLATGKLSPDAIPGKWTSQDSLLGMEFSGRDASGKRVMGLVPAKGLATSVLLSPDFLWDVPSNWTLEEAASVPVVYSTAYYALVVRGRVRPGETLLIHSGSGGVGQAAIAIALSLGCRVFTTVGSAEKRAYLQARFPQLDSTSFANSRDTSFEQHVLWHTGGKGVDLVLNSLAEEKLQASVRCLATHGRFLEIGKFDLSQNHPLGMAIFLKNVTFHGVLLDAFFNESSADWREVWALVQAGIRDGVVRPLKCTVFHGAQVEDAFRYMAQGKHIGKVVVQVLAEEPEAVLKGAKPKLMSAISKTFCPAHKSYIIAGGLGGFGLELAQWLIQRGVQKLVLTSRSGIRTGYQAKQVRRWRRQGVQVQVSTSNISSLEGARGLIAEAAQLGPVGGVFNLAVVLRDGLLENQTPEFFQDVCKPKYSGTLNLDRVTREACPELDYFVVFSSVSCGRGNAGQSNYGFANSAMERICEKRRHEGLPGLAVQWGAIGDVGILVETMSTNDTIVSGTLPQRMASCLEVLDLFLNQPHMVLSSFVLAEKAAAYRDRDSQRDLVEAVAHILGIRDLAAVNLDSSLADLGLDSLMSVEVRQTLERELNLVLSVREVRQLTLRKLQELSSKADEASELACPTPKEDGLAQQQTQLNLRSLLVNPEGPTLMRLNSVQSSERPLFLVHPIEGSTTVFHSLASRLSIPTYGLQCTRAAPLDSIHSLAAYYIDCIRQVQPEGPYRVAGYSYGACVAFEMCSQLQAQQSPAPTHNSLFLFDGSPTYVLAYTQSYRAKLTPGCEAEAETEAICFFVQQFTDMEHNRVLEALLPLKGLEERVAAAVDLIIKSHQGLDRQELSFAARSFYYKLRAAEQYTPKAKYHGNVMLLRAKTGGAYGEDLGADYNLSQVCDGKVSVHVIEGDHRTLLEGSGLESIISIIHSSLAEPRVSVREG", "length": 2511, "reference_go_mf": ["GO:0019171", "GO:0004316", "GO:0004315", "GO:0004313", "GO:0004314", "GO:0045296", "GO:0141148", "GO:0004312", "GO:0016297", "GO:0042802", "GO:0031177", "GO:0003723"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_975_4ecs_assembly1", "enzyme_name": "DNA polymerase eta", "ec": ["2.7.7.7"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q9Y253", "alignment_score": 846.0, "observed_coverage": 0.9930232558139535, "aligned_identity": 1.0, "canonical_span": [0, 432], "sequence": "MATGQDRVVALVDMDCFFVQVEQRQNPHLRNKPCAVVQYKSWKGGGIIAVSYEARAFGVTRSMWADDAKKLCPDLLLAQVRESRGKANLTKYREASVEVMEIMSRFAVIERASIDEAYVDLTSAVQERLQKLQGQPISADLLPSTYIEGLPQGPTTAEETVQKEGMRKQGLFQWLDSLQIDNLTSPDLQLTVGAVIVEEMRAAIERETGFQCSAGISHNKVLAKLACGLNKPNRQTLVSHGSVPQLFSQMPIRKIRSLGGKLGASVIEILGIEYMGELTQFTESQLQSHFGEKNGSWLYAMCRGIEHDPVKPRQLPKTIGCSKNFPGKTALATREQVQWWLLQLAQELEERLTKDRNDNDRVATQLVVSIRVQGDKRLSSLRRCCALTRYDAHKMSHDAFTVIKNCNTSGIQTEWSPPLTMLFLCATKFSASAPSSSTDITSFLSSDPSSLPKVPVTSSEAKTQGSGPAVTATKKATTSLESFFQKAAERQKVKEASLSSLTAPTQAPMSNSPSKPSLPFQTSQSTGTEPFFKQKSLLLKQKQLNNSSVSSPQQNPWSNCKALPNSLPTEYPGCVPVCEGVSKLEESSKATPAEMDLAHNSQSMHASSASKSVLEVTQKATPNPSLLAAEDQVPCEKCGSLVPVWDMPEHMDYHFALELQKSFLQPHSSNPQVVSAVSHQGKRNPKSPLACTNKRPRPEGMQTLESFFKPLTH", "length": 713, "reference_go_mf": ["GO:0003684", "GO:0034061", "GO:0003887"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_bd58c0aff528af696189"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_976_2qmj_assembly1", "enzyme_name": "\u03b1\u2011glucosidase maltase-glucoamylase", "ec": ["3.2.1.20"], "controls": [{"chain": "A", "status": "reference_overlength", "selected": {"accession": "O43451", "alignment_score": 1713.0, "observed_coverage": 0.9976825028968713, "aligned_identity": 0.9988385598141696, "canonical_span": [92, 954], "sequence": "MARKKLKKFTTLEIVLSVLLLVLFIISIVLIVLLAKESLKSTAPDPGTTGTPDPGTTGTPDPGTTGTTHARTTGPPDPGTTGTTPVSAECPVVNELERINCIPDQPPTKATCDQRGCCWNPQGAVSVPWCYYSKNHSYHVEGNLVNTNAGFTARLKNLPSSPVFGSNVDNVLLTAEYQTSNRFHFKLTDQTNNRFEVPHEHVQSFSGNAAASLTYQVEISRQPFSIKVTRRSNNRVLFDSSIGPLLFADQFLQLSTRLPSTNVYGLGEHVHQQYRHDMNWKTWPIFNRDTTPNGNGTNLYGAQTFFLCLEDASGLSFGVFLMNSNAMEVVLQPAPAITYRTIGGILDFYVFLGNTPEQVVQEYLELIGRPALPSYWALGFHLSRYEYGTLDNMREVVERNRAAQLPYDVQHADIDYMDERRDFTYDSVDFKGFPEFVNELHNNGQKLVIIVDPAISNNSSSSKPYGPYDRGSDMKIWVNSSDGVTPLIGEVWPGQTVFPDYTNPNCAVWWTKEFELFHNQVEFDGIWIDMNEVSNFVDGSVSGCSTNNLNNPPFTPRILDGYLFCKTLCMDAVQHWGKQYDIHNLYGYSMAVATAEAAKTVFPNKRSFILTRSTFAGSGKFAAHWLGDNTATWDDLRWSIPGVLEFNLFGIPMVGPDICGFALDTPEELCRRWMQLGAFYPFSRNHNGQGYKDQDPASFGADSLLLNSSRHYLNIRYTLLPYLYTLFFRAHSRGDTVARPLLHEFYEDNSTWDVHQQFLWGPGLLITPVLDEGAEKVMAYVPDAVWYDYETGSQVRWRKQKVEMELPGDKIGLHLRGGYIFPTQQPNTTTLASRKNPLGLIIALDENKEAKGELFWDNGETKDTVANKVYLLCEFSVTQNRLEVNISQSTYKDPNNLAFNEIKILGTEEPSNVTVKHNGVPSQTSPTVTYDSNLKVAIITDIDLLLGEAYTVEWSIKIRDEEKIDCYPDENGASAENCTARGCIWEASNSSGVPFCYFVNDLYSVSDVQYNSHGATADISLKSSVYANAFPSTPVNPLRLDVTYHKNEMLQFKIYDPNKNRYEVPVPLNIPSMPSSTPEGQLYDVLIKKNPFGIEIRRKSTGTIIWDSQLLGFTFSDMFIRISTRLPSKYLYGFGETEHRSYRRDLEWHTWGMFSRDQPPGYKKNSYGVHPYYMGLEEDGSAHGVLLLNSNAMDVTFQPLPALTYRTTGGVLDFYVFLGPTPELVTQQYTELIGRPVMVPYWSLGFQLCRYGYQNDSEIASLYDEMVAAQIPYDVQYSDIDYMERQLDFTLSPKFAGFPALINRMKADGMRVILILDPAISGNETQPYPAFTRGVEDDVFIKYPNDGDIVWGKVWPDFPDVVVNGSLDWDSQVELYRAYVAFPDFFRNSTAKWWKREIEELYNNPQNPERSLKFDGMWIDMNEPSSFVNGAVSPGCRDASLNHPPYMPHLESRDRGLSSKTLCMESQQILPDGSLVQHYNVHNLYGWSQTRPTYEAVQEVTGQRGVVITRSTFPSSGRWAGHWLGDNTAAWDQLKKSIIGMMEFSLFGISYTGADICGFFQDAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQDPVSWDAAFVNISRNVLQTRYTLLPYLYTLMQKAHTEGVTVVRPLLHEFVSDQVTWDIDSQFLLGPAFLVSPVLERNARNVTAYFPRARWYDYYTGVDINARGEWKTLPAPLDHINLHVRGGYILPWQEPALNTHLSRKNPLGLIIALDENKEAKGELFWDDGQTKDTVAKKVYLLCEFSVTQNHLEVTISQSTYKDPNNLAFNEIKILGMEEPSNVTVKHNGVPSQTSPTVTYDSNLKVAIITDINLFLGEAYTVEWSIKIRDEEKIDCYPDENGDSAENCTARGCIWEASNSSGVPFCYFVNDLYSVSDVQYNSHGATADISLKSSVHANAFPSTPVNPLRLDVTYHKNEMLQFKIYDPNNNRYEVPVPLNIPSVPSSTPEGQLYDVLIKKNPFGIEIRRKSTGTIIWDSQLLGFTFNDMFIRISTRLPSKYLYGFGETEHTSYRRDLEWHTWGMFSRDQPPGYKKNSYGVHPYYMGLEEDGSAHGVLLLNSNAMDVTFQPLPALTYRTTGGVLDFYVFLGPTPELVTQQYTELIGRPVMVPYWSLGFQLCRYGYQNDSEISSLYDEMVAAQIPYDVQYSDIDYMERQLDFTLSPKFAGFPALINRMKADGMRVILILDPAISGNETQPYPAFTRGVEDDVFIKYPNDGDIVWGKVWPDFPDVVVNGSLDWDSQVELYRAYVAFPDFFRNSTAKWWKREIEELYNNPQNPERSLKFDGMWIDMNEPSSFVNGAVSPGCRDASLNHPPYMPYLESRDRGLSSKTLCMESQQILPDGSPVQHYNVHNLYGWSQTRPTYEAVQEVTGQRGVVITRSTFPSSGRWAGHWLGDNTAAWDQLKKSIIGMMEFSLFGISYTGADICGFFQDAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQDPVSWDVAFVNISRTVLQTRYTLLPYLYTLMHKAHTEGVTVVRPLLHEFVSDQVTWDIDSQFLLGPAFLVSPVLERNARNVTAYFPRARWYDYYTGVDINARGEWKTLPAPLDHINLHVRGGYILPWQEPALNTHLSRQKFMGFKIALDDEGTAGGWLFWDDGQSIDTYGKGLYYLASFSASQNTMQSHIIFNNYITGTNPLKLGYIEIWGVGSVPVTSVSISVSGMVITPSFNNDPTTQVLSIDVTDRNISLHNFTSLTWISTL", "length": 2753, "reference_go_mf": ["GO:0004558", "GO:0016160", "GO:0030246", "GO:0003824", "GO:0004574"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_978_3nye_assembly1", "enzyme_name": "D-arginine dehydrogenase", "ec": ["1.4.99.6"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q9HXE3", "alignment_score": 748.0, "observed_coverage": 0.9816272965879265, "aligned_identity": 1.0, "canonical_span": [1, 375], "sequence": "MIEADYLVIGAGIAGASTGYWLSAHGRVVVLEREAQPGYHSTGRSAAHYTVAYGTPQVRALTAASRAFFDNPPAGFCEHPLLSPRPEMVVDFSDDPEELRRQYESGKALVPQMRLLDAEQACSIVPVLRRDKVFGATYDPTGADIDTDALHQGYLRGIRRNQGQVLCNHEALEIRRVDGAWEVRCDAGSYRAAVLVNAAGAWCDAIAGLAGVRPLGLQPKRRSAFIFAPPPGIDCHDWPMLVSLDESFYLKPDAGMLLGSPANADPVEAHDVQPEQLDIATGMYLIEEATTLTIRRPEHTWAGLRSFVADGDLVAGYAANAEGFFWVAAQGGYGIQTSAAMGEASAALIRHQPLPAHLREHGLDEAMLSPRRLSP", "length": 375, "reference_go_mf": ["GO:0008718"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_c120a2d24d855ba6a7c7"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_979_3mvf_assembly1", "enzyme_name": "nitrite dismutase", "ec": ["1.7.6.1"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q94734", "alignment_score": 368.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [21, 205], "sequence": "MKSYTSLLAVAILCLFGGVNGACTKNAIAQTGFNKDKYFNGDVWYVTDYLDLEPDDVPKRYCAALAAGTASGKLKEALYHYDPKTQDTFYDVSELQVESLGKYTANFKKVDKNGNVKVAVTAGNYYTFTVMYADDSSALIHTCLHKGNKDLGDLYAVLNRNKDAAAGDKVKSAVSAATLEFSKFISTKENNCAYDNDSLKSLLTK", "length": 205, "reference_go_mf": ["GO:0051381", "GO:0070026"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_cfd16c70982bb350ff77"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_97_1ctt_assembly1", "enzyme_name": "cytidine deaminase", "ec": ["3.5.4.5"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0ABF6", "alignment_score": 588.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 294], "sequence": "MHPRFQTAFAQLADNLQSALEPILADKYFPALLTGEQVSSLKSATGLDEDALAFALLPLAAACARTPLSNFNVGAIARGVSGTWYFGANMEFIGATMQQTVHAEQSAISHAWLSGEKALAAITVNYTPCGHCRQFMNELNSGLDLRIHLPGREAHALRDYLPDAFGPKDLEIKTLLMDEQDHGYALTGDALSQAAIAAANRSHMPYSKSPSGVALECKDGRIFSGSYAENAAFNPTLPPLQGALILLNLKGYDYPDIQRAVLAEKADAPLIQWDATSATLKALGCHSIDRVLLA", "length": 294, "reference_go_mf": ["GO:0004126", "GO:0042802", "GO:0042803", "GO:0001884", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_9d23d20894fb5ed8711c"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_980_1dj7_assembly1", "enzyme_name": "ferredoxin:thioredoxin reductase", "ec": ["1.8.7.2"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q55389", "alignment_score": 218.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [7, 116], "sequence": "MTSSDTQNNKTLAAMKNFAEQYAKRTDTYFCSDLSVTAVVIEGLARHKEELGSPLCPCRHYEDKEAEVKNTFWNCPCVPMRERKECHCMLFLTPDNDFAGDAQDIPMETLEEVKASMA", "length": 118, "reference_go_mf": ["GO:0051539", "GO:0009055", "GO:0103012", "GO:0016730"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_bbe8d0693ec39ff0a1d6"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_981_5odi_assembly1", "enzyme_name": "ferredoxin:CoB-CoM heterodisulfide reductase", "ec": ["1.8.7.3"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "A0A2D0TCB4", "alignment_score": 582.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 291], "sequence": "MKYAFFLGCIMPNRYAGVEAATRTVMEKLGVELVDMTGASCCPAPGVFGSFDQKTWLTLAARNLCIAEEMGVDIVTVCNGCYGSLFEAAHLLHDNKEALNFVNEKLDKVGKEYKGNVKVRHFAELIYNDIGVDKIAEKVERPLNINVGVHYGCHFLKPTDVKHLGSAERPVMLDEIVEATGAKSVPYADKMMCCGAGGGVRARELELSLDMTNEKIENMIKAGADCTVNVCPFCHLQFDRGQIEIKEKFGKEYNFPVLHLSQLLGLAMGMDPKDLALSVHQISVDPLLKKI", "length": 291, "reference_go_mf": ["GO:0051912"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_cfab3c5e046291b87fb8"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_982_2ble_assembly1", "enzyme_name": "GMP reductase", "ec": ["1.7.1.7"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P36959", "alignment_score": 657.0, "observed_coverage": 1.0, "aligned_identity": 0.9970326409495549, "canonical_span": [0, 343], "sequence": "MPRIDADLKLDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGTFEMAAVMSQHSMFTAIHKHYSLDDWKLFATNHPECLQNVAVSSGSGQNDLEKMTSILEAVPQVKFICLDVANGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVGPGSVCTTRTKTGVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLGGMFSGHTECAGEVFERNGRKLKLFYGMSSDTAMNKHAGGVAEYRASEGKTVEVPYKGDVENTILDILGGLRSTCTYVGAAKLKELSRRATFIRVTQQHNTVFS", "length": 345, "reference_go_mf": ["GO:0003920"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_c6b212cc9b074f28c25e"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_983_2ime_assembly1", "enzyme_name": "2-hydroxychromene-2-carboxylate isomerase", "ec": ["5.99.1.4"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q51948", "alignment_score": 406.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 203], "sequence": "MIVDFYFDFLSPFSYLANQRLSKLAQDYGLTIRYNAIDLARVKIAIGNVGPSNRDLKVKLDYLKVDLQRWAQLYGIPLVFPANYNSRRMNIGFYYSGAEAQAAAYVNVVFNAVWGEGIAPDLESLPALVSEKLGWDRSAFEHFLSSNAATERYDEQTHAAIERKVFGVPTMFLGDEMWWGNDRLFMLESAMGRLCRQNADLSS", "length": 203, "reference_go_mf": ["GO:0018845", "GO:0004602", "GO:0004364"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_c3747247e683536c94ea"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_987_3amz_assembly1", "enzyme_name": "xanthine oxidase", "ec": ["1.17.3.2"], "controls": [{"chain": "A", "status": "reference_overlength", "selected": {"accession": "P80457", "alignment_score": 2543.0, "observed_coverage": 1.0, "aligned_identity": 0.9992254066615027, "canonical_span": [2, 1332], "sequence": "MTADELVFFVNGKKVVEKNADPETTLLAYLRRKLGLRGTKLGCGEGGCGACTVMLSKYDRLQDKIIHFSANACLAPICTLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGIVMSMYTLLRNQPEPTVEEIEDAFQGNLCRCTGYRPILQGFRTFAKNGGCCGGNGNNPNCCMNQKKDHTVTLSPSLFNPEEFMPLDPTQEPIFPPELLRLKDVPPKQLRFEGERVTWIQASTLKELLDLKAQHPEAKLVVGNTEIGIEMKFKNQLFPMIICPAWIPELNAVEHGPEGISFGAACALSSVEKTLLEAVAKLPTQKTEVFRGVLEQLRWFAGKQVKSVASLGGNIITASPISDLNPVFMASGTKLTIVSRGTRRTVPMDHTFFPSYRKTLLGPEEILLSIEIPYSREDEFFSAFKQASRREDDIAKVTCGMRVLFQPGSMQVKELALCYGGMADRTISALKTTQKQLSKFWNEKLLQDVCAGLAEELSLSPDAPGGMIEFRRTLTLSFFFKFYLTVLKKLGKDSKDKCGKLDPTYTSATLLFQKDPPANIQLFQEVPNGQSKEDTVGRPLPHLAAAMQASGEAVYCDDIPRYENELFLRLVTSTRAHAKIKSIDVSEAQKVPGFVCFLSADDIPGSNETGLFNDETVFAKDTVTCVGHIIGAVVADTPEHAERAAHVVKVTYEDLPAIITIEDAIKNNSFYGSELKIEKGDLKKGFSEADNVVSGELYIGGQDHFYLETHCTIAIPKGEEGEMELFVSTQNAMKTQSFVAKMLGVPVNRILVRVKRMGGGFGGKETRSTLVSVAVALAAYKTGHPVRCMLDRNEDMLITGGRHPFLARYKVGFMKTGTIVALEVDHYSNAGNSRDLSHSIMERALFHMDNCYKIPNIRGTGRLCKTNLSSNTAFRGFGGPQALFIAENWMSEVAVTCGLPAEEVRWKNMYKEGDLTHFNQRLEGFSVPRCWDECLKSSQYYARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGALIHVYTDGSVLVSHGGTEMGQGLHTKMVQVASKALKIPISKIYISETSTNTVPNSSPTAASVSTDIYGQAVYEACQTILKRLEPFKKKNPDGSWEDWVMAAYQDRVSLSTTGFYRTPNLGYSFETNSGNAFHYFTYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAFVQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPTEFRVSLLRDCPNKKAIYASKAVGEPPLFLGASVFFAIKDAIRAARAQHTNNNTKELFRLDSPATPEKIRNACVDKFTTLCVTGAPGNCKPWSLRV", "length": 1332, "reference_go_mf": ["GO:0051537", "GO:0071949", "GO:0050660", "GO:0005506", "GO:0030151", "GO:0043546", "GO:0042803", "GO:0004854", "GO:0004855"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_989_4e7k_assembly1", "enzyme_name": "Retroviral integrase", "ec": ["2.7.7.-"], "controls": [{"chain": "A", "status": "reference_overlength", "selected": {"accession": "P14350", "alignment_score": 726.0, "observed_coverage": 1.0, "aligned_identity": 0.994535519125683, "canonical_span": [759, 1125], "sequence": "MNPLQLLQPLPAEIKGTKLLAHWDSGATITCIPESFLEDEQPIKKTLIKTIHGEKQQNVYYVTFKVKGRKVEAEVIASPYEYILLSPTDVPWLTQQPLQLTILVPLQEYQEKILSKTALPEDQKQQLKTLFVKYDNLWQHWENQVGHRKIRPHNIATGDYPPRPQKQYPINPKAKPSIQIVIDDLLKQGVLTPQNSTMNTPVYPVPKPDGRWRMVLDYREVNKTIPLTAAQNQHSAGILATIVRQKYKTTLDLANGFWAHPITPESYWLTAFTWQGKQYCWTRLPQGFLNSPALFTADVVDLLKEIPNVQVYVDDIYLSHDDPKEHVQQLEKVFQILLQAGYVVSLKKSEIGQKTVEFLGFNITKEGRGLTDTFKTKLLNITPPKDLKQLQSILGLLNFARNFIPNFAELVQPLYNLIASAKGKYIEWSEENTKQLNMVIEALNTASNLEERLPEQRLVIKVNTSPSAGYVRYYNETGKKPIMYLNYVFSKAELKFSMLEKLLTTMHKALIKAMDLAMGQEILVYSPIVSMTKIQKTPLPERKALPIRWITWMTYLEDPRIQFHYDKTLPELKHIPDVYTSSQSPVKHPSQYEGVFYTDGSAIKSPDPTKSNNAGMGIVHATYKPEYQVLNQWSIPLGNHTAQMAEIAAVEFACKKALKIPGPVLVITDSFYVAESANKELPYWKSNGFVNNKKKPLKHISKWKSIAECLSMKPDITIQHEKGISLQIPVFILKGNALADKLATQGSYVVNCNTKKPNLDAELDQLLQGHYIKGYPKQYTYFLEDGKVKVSRPEGVKIIPPQSDRQKIVLQAHNLAHTGREATLLKIANLYWWPNMRKDVVKQLGRCQQCLITNASNKASGPILRPDRPQKPFDKFFIDYIGPLPPSQGYLYVLVVVDGMTGFTWLYPTKAPSTSATVKSLNVLTSIAIPKVIHSDQGAAFTSSTFAEWAKERGIHLEFSTPYHPQSGSKVERKNSDIKRLLTKLLVGRPTKWYDLLPVVQLALNNTYSPVLKYTPHQLLFGIDSNTPFANQDTLDLTREEELSLLQEIRTSLYHPSTPPASSRSWSPVVGQLVQERVARPASLRPRWHKPSTVLKVLNPRTVVILDHLGNNRTVSIDNLKPTSHQNGTTNDTATMDHLEKNE", "length": 1143, "reference_go_mf": ["GO:0004190", "GO:0003887", "GO:0046872", "GO:0003723", "GO:0003964", "GO:0004523"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_98_1bsz_assembly3", "enzyme_name": "peptide deformylase", "ec": ["3.5.1.88"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P0A6K3", "alignment_score": 336.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 169], "sequence": "MSVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEEGIGLAATQVDIHQRIIVIDVSENRDERLVLINPELLEKSGETGIEEGCLSIPEQRALVPRAEKVKIRALDRDGKPFELEADGLLAICIQHEMDHLVGKLFMDYLSPLKQQRIRQKVEKLDRLKARA", "length": 169, "reference_go_mf": ["GO:0008198", "GO:0016787", "GO:0042586", "GO:0043022", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_429ed288112c82dabf95"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_994_4bzc_assembly1", "enzyme_name": "deoxynucleoside triphosphate triphosphohydrolase SAMHD1", "ec": ["3.1.5.-"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q9Y3Z3", "alignment_score": 936.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [113, 599], "sequence": "MQRADSEQPSKRPRCDDSPRTPSNTPSAEADWSPGLELHPDYKTWGPEQVCSFLRRGGFEEPVLLKNIRENEITGALLPCLDESRFENLGVSSLGERKKLLSYIQRLVQIHVDTMKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCHDLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDICFIKEQIVGPLESPVEDSLWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDYGMQEKNPIDHVSFYCKTAPNRAIRITKNQVSQLLPEKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQDGDVIAPLITPQKKEWNDSTSVQNPTRLREASKSRVQLFKDDPM", "length": 626, "reference_go_mf": ["GO:0106375", "GO:0032567", "GO:0008832", "GO:0042802", "GO:0003676", "GO:0003723", "GO:0004540", "GO:0003697", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_ffb7be25bb08beb814c2"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_995_2et1_assembly1", "enzyme_name": "oxalate oxidase", "ec": ["1.2.3.4"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P45850", "alignment_score": 400.0, "observed_coverage": 0.9950248756218906, "aligned_identity": 1.0, "canonical_span": [1, 201], "sequence": "SDPDPLQDFCVADLDGKAVSVNGHTCKPMSEAGDDFLFSSKLTKAGNTSTPNGSAVTELDVAEWPGTNTLGVSMNRVDFAPGGTNPPHIHPRATEIGMVMKGELLVGILGSLDSGNKLYSRVVRAGETFVIPRGLMHFQFNVGKTEAYMVVSFNSQNPGIVFVPLTLFGSDPPIPTPVLTKALRVEAGVVELLKSKFAGGS", "length": 201, "reference_go_mf": ["GO:0042802", "GO:0030145", "GO:0050162", "GO:0004784"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_dd5aad40c429bcf2e39a"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_997_6fkw_assembly1", "enzyme_name": "lanthanide-dependent methanol dehydrogenase", "ec": ["1.1.2.10"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "I0JWN7", "alignment_score": 1152.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [34, 610], "sequence": "MTVKLKKPKKYAVAKNATLLAAFGLIGSLSLAKANDELIKLEKEPGQWVMQNKNYANTRYSELNQINTKNVSRLRLAWSFSTGALRGHEGGPLVVGTTMYVHSAYPNHVYALDLTQKPYAIKWQYTPVQNSQAVAVACCDVVNRGLAYANGKIFMTTLDGQIIALDANTGKELWKMKHADVTKGETITGAPLVVKDKVLVGVSGGEFGVRGRVGAYDINTGNRVWLAYSQGPDEEVLLDSDFNKEFPQHGGPGDGTKTWPGEQWKLGGGTTWGWYSYDPALDLFYYGTSNPGTWNAEQRKGGDNKWSCTIFARRPDTGKARWAYQMTPWDSWDYDGVNEMILPDLTVKGKKTPCLVHFDRNGFGYVLDRRTGQLIEAQPFVYVNWAKEISKENDRPVEIPEKRTKQGVDTKGICPNSMGGKDQQPAAFSPQTGLFYVPTNNMCMNYEGVEATYTAGAPYVGANVLMYSGHEGKDDYYGAFICYDALKGKRVWEIHEHFPVWSGPVVTAGGLAFYGTMDGWFKAVDIKTGKVLWQQKLGSGIIGNPITFLGPDKKQYVAVYSGVGGWFGIAVAQNLPPDDPYAGLGAVGVAYQAGLPKATTVGGELYVFALE", "length": 611, "reference_go_mf": ["GO:0052933", "GO:0005509"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_ee0cf463ab7fd6d8e417"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_998_5g0i_assembly1", "enzyme_name": "histone deacetylase 6 enzyme (HDAC6)", "ec": ["3.5.1.98"], "controls": [{"chain": "A", "status": "reference_overlength", "selected": {"accession": "F8W4B7", "alignment_score": 1427.5, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [57, 801], "sequence": "MDAVPDTKGSSGPPRGTPETKNNKKNLQEARRKGRMDRSKAEEEMSNELQNLDVQGKSKATGTGLVYVDAFTRFHCLWDASHPECPARVSTVMEMLETEGLLGRCVQVEARAVTEDELLLVHTKEYVELMKSTQNMTEEELKTLAEKYDSVYLHPGFFSSACLSVGSVLQLVDKVMTSQLRNGFSINRPPGHHAQADKMNGFCMFNNLAIAARYAQKRHRVQRVLIVDWDVHHGQGIQYIFEEDPSVLYFSVHRYEDGSFWPHLKESDSSSVGSGAGQGYNINLPWNKVGMESGDYITAFQQLLLPVAYEFQPQLVLVAAGFDAVIGDPKGGMQVSPECFSILTHMLKGVAQGRLVLALEGGYNLQSTAEGVCASMRSLLGDPCPHLPSSGAPCESALKSISKTISDLYPFWKSLQTFEGGPLSEVSPLPAPVCAEVKVSSPITGLVYDQRMMLHHNMWDSHHPELPQRISRIFSRHEELRLLSRCHRIPARLATEEELALCHSSKHISIIKSSEHMKPRDLNRLGDEYNSIFISNESYTCALLAAGSCFNSAQAILTGQVRNAVAIVRPPGHHAEKDTACGFCFFNTAALTARYAQSITRESLRVLIVDWDVHHGNGTQHIFEEDDSVLYISLHRYEDGAFFPNSEDANYDKVGLGKGRGYNVNIPWNGGKMGDPEYMAAFHHLVMPIAREFAPELVLVSAGFDAARGDPLGGFQVTPEGYAHLTHQLMSLAAGRVLIILEGGYNLTSISESMSMCTSMLLGDSPPSLDHLTPLKTSATVSINNVLRAHAPFWSSLRVNIPESLRLSLPSPKPKGKCTPGGKGKKSPRQSTPSQSPGQATHRPDQSGFDELTADLLSLNLNTSTSSNTSPESVAVGGARRKVKPNTHRVSAGLESESPLKLNPEKAGAGDDTDVKAETPNRSISEPVVTCDSSAVKDQESLVLEAAGGNTVQSVLERVFGAQATDVDTMYVVDPLPWCPHLESVRPVPAGGIDVFQPCEECGGEAENWICLFCYKVLCGRYVNQHMVTHGQESGHPVVLSFADLSVWCYACESYVHNKVLHEAKNAAHLVKFGEGIHPFN", "length": 1081, "reference_go_mf": ["GO:0019213", "GO:0030955", "GO:0033558", "GO:0042903", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_999_1t8u_assembly1", "enzyme_name": "heparan sulfate glucosamine 3-O-sulfotransferase", "ec": ["2.8.2.30"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "Q9Y663", "alignment_score": 523.0, "observed_coverage": 0.9888059701492538, "aligned_identity": 1.0, "canonical_span": [138, 406], "sequence": "MAPPGPASALSTSAEPLSRSIFRKFLLMLCSLLTSLYVFYCLAERCQTLSGPVVGLSGGGEEAGAPGGGVLAGGPRELAVWPAAAQRKRLLQLPQWRRRRPPAPRDDGEEAAWEEESPGLSGGPGGSGAGSTVAEAPPGTLALLLDEGSKQLPQAIIIGVKKGGTRALLEFLRVHPDVRAVGAEPHFFDRSYDKGLAWYRDLMPRTLDGQITMEKTPSYFVTREAPARISAMSKDTKLIVVVRDPVTRAISDYTQTLSKRPDIPTFESLTFKNRTAGLIDTSWSAIQIGIYAKHLEHWLRHFPIRQMLFVSGERLISDPAGELGRVQDFLGLKRIITDKHFYFNKTKGFPCLKKAEGSSRPHCLGKTKGRTHPEIDREVVRRLREFYRPFNLKFYQMTGHDFGWDG", "length": 406, "reference_go_mf": ["GO:0008467", "GO:0008146"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_856f5b64b17070343e71"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_99_1g72_assembly1", "enzyme_name": "methanol dehydrogenase (cytochrome c)", "ec": ["1.1.2.7"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P38539", "alignment_score": 1142.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [2, 573], "sequence": "MADADLDKQVNTAGAWPIATGGYYSQHNSPLAQINKSNVKNVKAAWSFSTGVLNGHEGAPLVIGDMMYVHSAFPNNTYALNLNDPGKIVWQHKPKQDASTKAVMCCDVVDRGLAYGAGQIVKKQANGHLLALDAKTGKINWEVEVCDPKVGSTLTQAPFVAKDTVLMGCSGAELGVRGAVNAFDLKTGELKWRAFATGSDDSVRLAKDFNSANPHYGQFGLGTKTWEGDAWKIGGGTNWGWYAYDPKLNLFYYGSGNPAPWNETMRPGDNKWTMTIWGRDLDTGMAKWGYQKTPHDEWDFAGVNQMVLTDQPVNGKMTPLLSHIDRNGILYTLNRENGNLIVAEKVDPAVNVFKKVDLKTGTPVRDPEFATRMDHKGTNICPSAMGFHNQGVDSYDPESRTLYAGLNHICMDWEPFMLPYRAGQFFVGATLAMYPGPNGPTKKEMGQIRAFDLTTGKAKWTKWEKFAAWGGTLYTKGGLVWYATLDGYLKALDNKDGKELWNFKMPSGGIGSPMTYSFKGKQYIGSMYGVGGWPGVGLVFDLTDPSAGLGAVGAFRELQNHTQMGGGLMVFSL", "length": 573, "reference_go_mf": ["GO:0052933", "GO:0005509"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_813b3fe0844172d16c7f"}, "alternative_alignments": [{"accession": "P38540", "alignment_score": 8.0, "observed_coverage": 0.0070052539404553416, "aligned_identity": 1.0, "canonical_span": [6, 10], "length": 91, "reference_go_mf": ["GO:0052933", "GO:0004022"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_9_5a1i_assembly1", "enzyme_name": "methionine adenosyltransferase", "ec": ["2.5.1.6"], "controls": [{"chain": "A", "status": "assigned", "selected": {"accession": "P31153", "alignment_score": 762.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [14, 395], "sequence": "MNGQLNGFHEAFIEEGTFLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACETVAKTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGVHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDSKTQVTVQYMQDRGAVLPIRVHTIVISVQHDEEVCLDEMRDALKEKVIKAVVPAKYLDEDTIYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKGGLCRRVLVQVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVIVRDLDLKKPIYQRTAAYGHFGRDSFPWEVPKKLKY", "length": 395, "reference_go_mf": ["GO:0005524", "GO:0042802", "GO:0004478", "GO:0036094"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_6536bd18f0366739cbf6"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "original_mapping"}
{"query_id": "mcsa_116_1hzz_assembly1_reviewed_v2", "enzyme_name": "NAD(P)+ transhydrogenase (AB-specific)", "ec": ["1.6.1.2"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "Q2RSB2", "alignment_score": 714.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 371], "sequence": "MKIAIPKERRPGEDRVAISPEVVKKLVGLGFEVIVEQGAGVGASITDDALTAAGATIASTAAQALSQADVVWKVQRPMTAEEGTDEVALIKEGAVLMCHLGALTNRPVVEALTKRKITAYAMELMPRISRAQSMDILSSQSNLAGYRAVIDGAYEFARAFPMMMTAAGTVPPARVLVFGVGVAGLQAIATAKRLGAVVMATDVRAATKEQVESLGGKFITVDDEAMKTAETAGGYAKEMGEEFRKKQAEAVLKELVKTDIAITTALIPGKPAPVLITEEMVTKMKPGSVIIDLAVEAGGNCPLSEPGKIVVKHGVKIVGHTNVPSRVAADASPLFAKNLLNFLTPHVDKDTKTLVMKLEDETVSGTCVTRDGAIVHPALTGQGA", "length": 384, "reference_go_mf": ["GO:0051287", "GO:0003957", "GO:0070403", "GO:0070404", "GO:0050661", "GO:0046983", "GO:0008750"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_9f2ab073d5007acb6ff1"}, "alternative_alignments": [{"accession": "Q2RSB4", "alignment_score": 9.0, "observed_coverage": 0.016574585635359115, "aligned_identity": 0.8333333333333334, "canonical_span": [151, 157], "length": 464, "reference_go_mf": ["GO:0050661", "GO:0008750"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}, {"chain": "b", "status": "assigned", "selected": {"accession": "Q2RSB4", "alignment_score": 348.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [290, 464], "sequence": "MTHSLTMAAYIVAGVLFILALRGLSNPESARNGNRMGMVGMAIAILTTLLSPSVQAYAWIVLAIAIGGAIGTVIAKKVLMTALPQLVAAFHSLVGMAAVLVATGALLNPEAYGIGSAGAIHAGSLVEMSLGLAVGAITFSGSVIAFGKLQGLIAGKPVTFPMQHPLNAVLGILLVVLLVVFAATESHTAYFALMILAFALGFLLIIPIGGADMPVVISMLNSYSGWAAAGIGFTLGNPLLIIAGALVGSSGAILSYIMCKGMNRSIFNVILGGFGSEGGVAAAGGAAGDRSVKAGSAEDAAFIMKNASKVIIVPGYGMAVAQAQHALREMADVLKKEGVEVSYAIHPVAGRMPGHMNVLLAEANVPYDEVFELEEINSSFQTADVAFVIGANDVTNPAAKTDPSSPIYGMPILDVEKAGTVLFIKRSMASGYAGVENELFFRNNTMMLFGDAKKMTEQIVQAMN", "length": 464, "reference_go_mf": ["GO:0050661", "GO:0008750"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_11f0e2611c82ad56e0cb"}, "alternative_alignments": [{"accession": "Q2RSB2", "alignment_score": 8.0, "observed_coverage": 0.022988505747126436, "aligned_identity": 1.0, "canonical_span": [166, 170], "length": 384, "reference_go_mf": ["GO:0051287", "GO:0003957", "GO:0070403", "GO:0070404", "GO:0050661", "GO:0046983", "GO:0008750"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "experimental_alternative_mapped"}
{"query_id": "mcsa_13_2bbk_assembly1_reviewed_v2", "enzyme_name": "amine dehydrogenase", "ec": ["1.4.9.1"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "P29894", "alignment_score": 704.0, "observed_coverage": 1.0, "aligned_identity": 0.9943661971830986, "canonical_span": [62, 417], "sequence": "MALPPNFMPLFRASLIGLGLGCSALALAASAQDAPEAETQAQETQGQAAARAAAADLAAGQDDEPRILEAPAPDARRVYVNDPAHFAAVTQQFVIDGEAGRVIGMIDGGFLPNPVVADDGSFIAHASTVFSRIARGERTDYVEVFDPVTLLPTADIELPDAPRFLVGTYPWMTSLTPDGKTLLFYQFSPAPAVGVVDLEGKAFKRMLDVPDCYHIFPTAPDTFFMHCRDGSLAKVAFGTEGTPEITHTEVFHPEDEFLINHPAYSQKAGRLVWPTYTGKIHQIDLSSGDAKFLPAVEALTEAERADGWRPGGWQQVAYHRALDRIYLLVDQRDEWRHKTASRLLVVLDAKTGERLAKFEMGHEIDSINVSQDEKPLLYALSTGDKTLYIHDAESGEELRSVNQLGHGPQVITTADMG", "length": 417, "reference_go_mf": ["GO:0030058", "GO:0052876"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_ad330e16b56df3020edb"}, "alternative_alignments": [{"accession": "P22619", "alignment_score": 7.0, "observed_coverage": 0.022535211267605635, "aligned_identity": 0.625, "canonical_span": [109, 117], "length": 188, "reference_go_mf": ["GO:0030058", "GO:0052876"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}, {"chain": "b", "status": "assigned", "selected": {"accession": "P22619", "alignment_score": 242.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [63, 188], "sequence": "MLGNFRFDDMVEKLSRRVAGQTSRRSVIGKLGTAMLGIGLVPLLPVDRRGRVSRANAADAPAGTDPRAKWVPQDNDIQACDYWRHCSIDGNICDCSGGSLTNCPPGTKLATASWVASCYNPTDGQSYLIAYRDCCGYNVSGRCPCLNTEGELPVYRPEFANDIIWCFGAEDDAMTYHCTISPIVGKAS", "length": 188, "reference_go_mf": ["GO:0030058", "GO:0052876"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_d013a439b8cdb28c2254"}, "alternative_alignments": [{"accession": "P29894", "alignment_score": 7.0, "observed_coverage": 0.04032258064516129, "aligned_identity": 0.8, "canonical_span": [332, 337], "length": 417, "reference_go_mf": ["GO:0030058", "GO:0052876"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_140_1l1l_assembly1_reviewed_v2", "enzyme_name": "ribonucleoside-triphosphate reductase (class II)", "ec": ["1.17.4.2"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "Q59490", "alignment_score": 1478.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 739], "sequence": "MSEEISLSAEFIDRVKASVKPHWGKLGWVTYKRTYARWLPEKGRSENWDETVKRVVEGNINLDPRLQDSPSLELKQSLTEEAERLYKLIYGLGATPSGRNLWISGTDYQRRTGDSLNNCWFVAIRPQKYGDSKIVPSYLGKQEKAVSMPFSFLFDELMKGGGVGFSVARSNISQIPRVDFAIDLQLVVDETSESYDASVKVGAVGKNELVQDADSIYYRLPDTREGWVLANALLIDLHFAQTNPDRKQKLILDLSDIRPYGAEIHGFGGTASGPMPLISMLLDVNEVLNNKAGGRLTAVDAADICNLIGKAVVAGNVRRSAELALGSNDDQDFISMKQDQEKLMHHRWASNNSVAVDSAFSGYQPIAAGIRENGEPGIVNLDLSKNYGRIVDGYQAGIDGDVEGTNPCGEISLANGEPCNLFEVFPLIAEEQGWDLQEVFALAARYAKRVTFSPYDWEISREIIQKNRRIGISMSGIQDWLLTRLGNRVVTGFKDDFDPETHEAIKVPVYDKRAIKMVDQLYKAVVKADQDYSKTLGCNESIKHTTVKPSGTVAKLAGASEGMHFHYGAYLIQRIRFQDSDPLLPALKACGYRTEADIYTENTTCVEFPIKAVGADNPNFASAGTVSIAEQFATQAFLQTYWSDNAVSCTITFQDSEGDQVESLLRQYRFITKSTSLLPYFGGSLQQAPKEPIDKETYEKRSQEITGNVEEVFSQLNSDVKDLELVDQTDCEGGACPIK", "length": 739, "reference_go_mf": ["GO:0031419", "GO:0000166", "GO:0004748", "GO:0008998"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_d3d126bb63d5c6eb77af"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "predicted", "review_disposition": "predicted_alternative_mapped"}
{"query_id": "mcsa_153_1rhs_assembly1_reviewed_v2", "enzyme_name": "thiosulfate sulfurtransferase (eukaryotic)", "ec": ["2.8.1.1"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "P00586", "alignment_score": 578.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 294], "sequence": "MVHQVLYRALVSTKWLAESVRAGKVGPGLRVLDASWYSPGTREARKEYLERHVPGASFFDIEECRDKASPYEVMLPSEAGFADYVGSLGISNDTHVVVYDGDDLGSFYAPRVWWMFRVFGHRTVSVLNGGFRNWLKEGHPVTSEPSRPEPAIFKATLNRSLLKTYEQVLENLESKRFQLVDSRAQGRYLGTQPEPDAVGLDSGHIRGSVNMPFMNFLTEDGFEKSPEELRAMFEAKKVDLTKPLIATCRKGVTACHIALAAYLCGKPDVAIYDGSWFEWFHRAPPETWVSQGKGGKA", "length": 297, "reference_go_mf": ["GO:0008097", "GO:0004792"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_cede549ef9fa656b1738"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_156_1mro_assembly1_reviewed_v2", "enzyme_name": "coenzyme-B sulfoethylthiotransferase", "ec": ["2.8.4.1"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "P11558", "alignment_score": 1056.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 549], "sequence": "MADKLFINALKKKFEESPEEKKTTFYTLGGWKQSERKTEFVNAGKEVAAKRGIPQYNPDIGTPLGQRVLMPYQVSTTDTYVEGDDLHFVNNAAMQQMWDDIRRTVIVGLNHAHAVIEKRLGKEVTPETITHYLETVNHAMPGAAVVQEHMVETHPALVADSYVKVFTGNDEIADEIDPAFVIDINKQFPEDQAETLKAEVGDGIWQVVRIPTIVSRTCDGATTSRWSAMQIGMSMISAYKQAAGEAATGDFAYAAKHAEVIHMGTYLPVRRARGENEPGGVPFGYLADICQSSRVNYEDPVRVSLDVVATGAMLYDQIWLGSYMSGGVGFTQYATAAYTDNILDDFTYFGKEYVEDKYGLCEAPNNMDTVLDVATEVTFYGLEQYEEYPALLEDQFGGSQRAAVVAAAAGCSTAFATGNAQTGLSGWYLSMYLHKEQHSRLGFYGYDLQDQCGASNVFSIRGDEGLPLELRGPNYPNYAMNVGHQGEYAGISQAPHAARGDAFVFNPLVKIAFADDNLVFDFTNVRGEFAKGALREFEPAGERALITPAK", "length": 550, "reference_go_mf": ["GO:0050524"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_98c8ca4e4ad470d7b8d2"}, "alternative_alignments": [{"accession": "P11560", "alignment_score": 12.0, "observed_coverage": 0.011049723756906077, "aligned_identity": 1.0, "canonical_span": [248, 254], "length": 443, "reference_go_mf": ["GO:0050524"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, {"accession": "P11562", "alignment_score": 8.0, "observed_coverage": 0.007366482504604052, "aligned_identity": 1.0, "canonical_span": [46, 50], "length": 249, "reference_go_mf": ["GO:0050524"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}, {"chain": "b", "status": "assigned", "selected": {"accession": "P11558", "alignment_score": 1056.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 549], "sequence": "MADKLFINALKKKFEESPEEKKTTFYTLGGWKQSERKTEFVNAGKEVAAKRGIPQYNPDIGTPLGQRVLMPYQVSTTDTYVEGDDLHFVNNAAMQQMWDDIRRTVIVGLNHAHAVIEKRLGKEVTPETITHYLETVNHAMPGAAVVQEHMVETHPALVADSYVKVFTGNDEIADEIDPAFVIDINKQFPEDQAETLKAEVGDGIWQVVRIPTIVSRTCDGATTSRWSAMQIGMSMISAYKQAAGEAATGDFAYAAKHAEVIHMGTYLPVRRARGENEPGGVPFGYLADICQSSRVNYEDPVRVSLDVVATGAMLYDQIWLGSYMSGGVGFTQYATAAYTDNILDDFTYFGKEYVEDKYGLCEAPNNMDTVLDVATEVTFYGLEQYEEYPALLEDQFGGSQRAAVVAAAAGCSTAFATGNAQTGLSGWYLSMYLHKEQHSRLGFYGYDLQDQCGASNVFSIRGDEGLPLELRGPNYPNYAMNVGHQGEYAGISQAPHAARGDAFVFNPLVKIAFADDNLVFDFTNVRGEFAKGALREFEPAGERALITPAK", "length": 550, "reference_go_mf": ["GO:0050524"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_98c8ca4e4ad470d7b8d2"}, "alternative_alignments": [{"accession": "P11560", "alignment_score": 12.0, "observed_coverage": 0.011049723756906077, "aligned_identity": 1.0, "canonical_span": [248, 254], "length": 443, "reference_go_mf": ["GO:0050524"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, {"accession": "P11562", "alignment_score": 8.0, "observed_coverage": 0.007366482504604052, "aligned_identity": 1.0, "canonical_span": [46, 50], "length": 249, "reference_go_mf": ["GO:0050524"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}, {"chain": "c", "status": "assigned", "selected": {"accession": "P11560", "alignment_score": 884.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 443], "sequence": "MAKFEDKVDLYDDRGNLVEEQVPLEALSPLRNPAIKSIVQGIKRTVAVNLEGIENALKTAKVGGPACKIMGRELDLDIVGNAESIAAAAKEMIQVTEDDDTNVELLGGGKRALVQVPSARFDVAAEYSAAPLVTATAFVQAIINEFDVSMYDANMVKAAVLGRYPQSVEYMGANIATMLDIPQKLEGPGYALRNIMVNHVVAATLKNTLQAAALSTILEQTAMFEMGDAVGAFERMHLLGLAYQGMNADNLVFDLVKANGKEGTVGSVIADLVERALEDGVIKVEKELTDYKVYGTDDLAMWNAYAAAGLMAATMVNQGAARAAQGVSSTLLYYNDLIEFETGLPSVDFGKVEGTAVGFSFFSHSIYGGGGPGIFNGNHIVTRHSKGFAIPCVAAAMALDAGTQMFSPEATSGLIKEVFSQVDEFREPLKYVVEAAAEIKNEI", "length": 443, "reference_go_mf": ["GO:0050524"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_cafa9aa1fec9ed0a8d15"}, "alternative_alignments": [{"accession": "P11558", "alignment_score": 12.0, "observed_coverage": 0.013574660633484163, "aligned_identity": 1.0, "canonical_span": [515, 521], "length": 550, "reference_go_mf": ["GO:0050524"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, {"accession": "P11562", "alignment_score": 8.0, "observed_coverage": 0.00904977375565611, "aligned_identity": 1.0, "canonical_span": [112, 116], "length": 249, "reference_go_mf": ["GO:0050524"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_158_1auk_assembly1_reviewed_v2", "enzyme_name": "cerebroside-sulfatase", "ec": ["3.1.6.8"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "P15289", "alignment_score": 946.5, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [18, 503], "sequence": "MGAPRSLLLALAAGLAVARPPNIVLIFADDLGYGDLGCYGHPSSTTPNLDQLAAGGLRFTDFYVPVSLCTPSRAALLTGRLPVRMGMYPGVLVPSSRGGLPLEEVTVAEVLAARGYLTGMAGKWHLGVGPEGAFLPPHQGFHRFLGIPYSHDQGPCQNLTCFPPATPCDGGCDQGLVPIPLLANLSVEAQPPWLPGLEARYMAFAHDLMADAQRQDRPFFLYYASHHTHYPQFSGQSFAERSGRGPFGDSLMELDAAVGTLMTAIGDLGLLEETLVIFTADNGPETMRMSRGGCSGLLRCGKGTTYEGGVREPALAFWPGHIAPGVTHELASSLDLLPTLAALAGAPLPNVTLDGFDLSPLLLGTGKSPRQSLFFYPSYPDEVRGVFAVRTGKYKAHFFTQGSAHSDTTADPACHASSSLTAHEPPLLYDLSKDPGENYNLLGGVAGATPEVLQALKQLQLLKAQLDAAVTFGPSQVARGEDPALQICCHPGCTPRPACCHCPDPHA", "length": 507, "reference_go_mf": ["GO:0004065", "GO:0005509", "GO:0004098", "GO:0008484"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_60700b018eb23070a345"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_172_1onw_assembly1_reviewed_v2", "enzyme_name": "isoaspartyl dipeptidase", "ec": ["3.4.19.5"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "P39377", "alignment_score": 732.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 389], "sequence": "MIDYTAAGFTLLQGAHLYAPEDRGICDVLVANGKIIAVASNIPSDIVPNCTVVDLSGQILCPGFIDQHVHLIGGGGEAGPTTRTPEVALSRLTEAGVTSVVGLLGTDSISRHPESLLAKTRALNEEGISAWMLTGAYHVPSRTITGSVEKDVAIIDRVIGVKCAISDHRSAAPDVYHLANMAAESRVGGLLGGKPGVTVFHMGDSKKALQPIYDLLENCDVPISKLLPTHVNRNVPLFEQALEFARKGGTIDITSSIDEPVAPAEGIARAVQAGIPLARVTLSSDGNGSQPFFDDEGNLTHIGVAGFETLLETVQVLVKDYDFSISDALRPLTSSVAGFLNLTGKGEILPGNDADLLVMTPELRIEQVYARGKLMVKDGKACVKGTFETA", "length": 390, "reference_go_mf": ["GO:0008798", "GO:0016810", "GO:0042802", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_7f8ef01869c7f3cbc2b4"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_174_9pap_assembly1_reviewed_v2", "enzyme_name": "papain", "ec": ["3.4.22.2"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "P00784", "alignment_score": 407.0, "observed_coverage": 1.0, "aligned_identity": 0.985781990521327, "canonical_span": [133, 345], "sequence": "MAMIPSISKLLFVAICLFVYMGLSFGDFSIVGYSQNDLTSTERLIQLFESWMLKHNKIYKNIDEKIYRFEIFKDNLKYIDETNKKNNSYWLGLNVFADMSNDEFKEKYTGSIAGNYTTTELSYEEVLNDGDVNIPEYVDWRQKGAVTPVKNQGSCGSCWAFSAVVTIEGIIKIRTGNLNEYSEQELLDCDRRSYGCNGGYPWSALQLVAQYGIHYRNTYPYEGVQRYCRSREKGPYAAKTDGVRQVQPYNEGALLYSIANQPVSVVLEAAGKDFQLYRGGIFVGPCGNKVDHAVAAVGYGPNYILIKNSWGTGWGENGYIRIKRGTGNSYGVCGLYTSSFYPVKN", "length": 345, "reference_go_mf": ["GO:0008234", "GO:0097655"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_65cbd981a100cb8f37ff"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_194_1p5d_assembly1_reviewed_v2", "enzyme_name": "phosphomannomutase/ phosphoglucomutase", "ec": ["5.4.2.8"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "P26276", "alignment_score": 902.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [8, 463], "sequence": "MSTAKAPTLPASIFRAYDIRGVVGDTLTAETAYWIGRAIGSESLARGEPCVAVGRDGRLSGPELVKQLIQGLVDCGCQVSDVGMVPTPVLYYAANVLEGKSGVMLTGSHNPPDYNGFKIVVAGETLANEQIQALRERIEKNDLASGVGSVEQVDILPRYFKQIRDDIAMAKPMKVVVDCGNGVAGVIAPQLIEALGCSVIPLYCEVDGNFPNHHPDPGKPENLKDLIAKVKAENADLGLAFDGDGDRVGVVTNTGTIIYPDRLLMLFAKDVVSRNPGADIIFDVKCTRRLIALISGYGGRPVMWKTGHSLIKKKMKETGALLAGEMSGHVFFKERWFGFDDGIYSAARLLEILSQDQRDSEHVFSAFPSDISTPEINITVTEDSKFAIIEALQRDAQWGEGNITTLDGVRVDYPKGWGLVRASNTTPVLVLRFEADTEEELERIKTVFRNQLKAVDSSLPVPF", "length": 463, "reference_go_mf": ["GO:0000287", "GO:0004614", "GO:0004615"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_314c39044225f390e14b"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_19_1dl2_assembly1_reviewed_v2", "enzyme_name": "mannosyl-oligosaccharide 1,2-alpha-mannosidase", "ec": ["3.2.1.113"], "controls": [{"chain": "a", "status": "reference_mapping_uncertain", "selected": {"accession": "Q9UKM7", "alignment_score": 68.5, "observed_coverage": 0.7176470588235294, "aligned_identity": 0.4890710382513661, "canonical_span": [317, 694], "sequence": "MAACEGRRSGALGSSQSDFLTPPVGGAPWAVATTVVMYPPPPPPPHRDFISVTLSFGENYDNSKSWRRRSCWRKWKQLSRLQRNMILFLLAFLLFCGLLFYINLADHWKALAFRLEEEQKMRPEIAGLKPANPPVLPAPQKADTDPENLPEISSQKTQRHIQRGPPHLQIRPPSQDLKDGTQEEATKRQEAPVDPRPEGDPQRTVISWRGAVIEPEQGTELPSRRAEVPTKPPLPPARTQGTPVHLNYRQKGVIDVFLHAWKGYRKFAWGHDELKPVSRSFSEWFGLGLTLIDALDTMWILGLRKEFEEARKWVSKKLHFEKDVDVNLFESTIRILGGLLSAYHLSGDSLFLRKAEDFGNRLMPAFRTPSKIPYSDVNIGTGVAHPPRWTSDSTVAEVTSIQLEFRELSRLTGDKKFQEAVEKVTQHIHGLSGKKDGLVPMFINTHSGLFTHLGVFTLGARADSYYEYLLKQWIQGGKQETQLLEDYVEAIEGVRTHLLRHSEPSKLTFVGELAHGRFSAKMDHLVCFLPGTLALGVYHGLPASHMELAQELMETCYQMNRQMETGLSPEIVHFNLYPQPGRRDVEVKPADRHNLLRPETVESLFYLYRVTGDRKYQDWGWEILQSFSRFTRVPSGGYSSINNVQDPQKPEPRDKMESFFLGETLKYLFLLFSDDPNLLSLDAYVFNTEAHPLPIWTPA", "length": 699, "reference_go_mf": ["GO:0005509", "GO:0004571"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_19_1x9d_assembly1_reviewed_v2", "enzyme_name": "mannosyl-oligosaccharide 1,2-alpha-mannosidase", "ec": ["3.2.1.113"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "Q9UKM7", "alignment_score": 896.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [244, 696], "sequence": "MAACEGRRSGALGSSQSDFLTPPVGGAPWAVATTVVMYPPPPPPPHRDFISVTLSFGENYDNSKSWRRRSCWRKWKQLSRLQRNMILFLLAFLLFCGLLFYINLADHWKALAFRLEEEQKMRPEIAGLKPANPPVLPAPQKADTDPENLPEISSQKTQRHIQRGPPHLQIRPPSQDLKDGTQEEATKRQEAPVDPRPEGDPQRTVISWRGAVIEPEQGTELPSRRAEVPTKPPLPPARTQGTPVHLNYRQKGVIDVFLHAWKGYRKFAWGHDELKPVSRSFSEWFGLGLTLIDALDTMWILGLRKEFEEARKWVSKKLHFEKDVDVNLFESTIRILGGLLSAYHLSGDSLFLRKAEDFGNRLMPAFRTPSKIPYSDVNIGTGVAHPPRWTSDSTVAEVTSIQLEFRELSRLTGDKKFQEAVEKVTQHIHGLSGKKDGLVPMFINTHSGLFTHLGVFTLGARADSYYEYLLKQWIQGGKQETQLLEDYVEAIEGVRTHLLRHSEPSKLTFVGELAHGRFSAKMDHLVCFLPGTLALGVYHGLPASHMELAQELMETCYQMNRQMETGLSPEIVHFNLYPQPGRRDVEVKPADRHNLLRPETVESLFYLYRVTGDRKYQDWGWEILQSFSRFTRVPSGGYSSINNVQDPQKPEPRDKMESFFLGETLKYLFLLFSDDPNLLSLDAYVFNTEAHPLPIWTPA", "length": 699, "reference_go_mf": ["GO:0005509", "GO:0004571"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_d7a2d8db6c843884094d"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_210_1m6k_assembly1_reviewed_v2", "enzyme_name": "beta-lactamase (Class D)", "ec": ["3.5.2.6"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "P13661", "alignment_score": 486.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [25, 276], "sequence": "MKNTIHINFAIFLIIANIIYSSASASTDISTVASPLFEGTEGCFLLYDASTNAEIAQFNKAKCATQMAPDSTFKIALSLMAFDAEIIDQKTIFKWDKTPKGMEIWNSNHTPKTWMQFSVVWVSQEITQKIGLNKIKNYLKDFDYGNQDFSGDKERNNGLTEAWLESSLKISPEEQIQFLRKIINHNLPVKNSAIENTIENMYLQDLDNSTKLYGKTGAGFTANRTLQNGWFEGFIISKSGHKYVFVSALTGNLGSNLTSSIKAKKNAITILNTLNL", "length": 276, "reference_go_mf": ["GO:0008800", "GO:0008658"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_60b3f65de060dfc3642b"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_219_1trk_assembly1_reviewed_v2", "enzyme_name": "transketolase", "ec": ["2.2.1.1"], "controls": [{"chain": "a", "status": "reference_mapping_uncertain", "selected": {"accession": "P29401", "alignment_score": 21.0, "observed_coverage": 0.048672566371681415, "aligned_identity": 0.5454545454545454, "canonical_span": [152, 185], "sequence": "MESYHKPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKSQDPRNPHNDRFVLSKGHAAPILYAVWAEAGFLAEAELLNLRKISSDLDGHPVPKQAFTDVATGSLGQGLGAACGMAYTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVAILDINRLGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDGHSVEELCKAFGQAKHQPTAIIAKTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQSKKKILATPPQEDAPSVDIANIRMPSLPSYKVGDKIATRKAYGQALAKLGHASDRIIALDGDTKNSTFSEIFKKEHPDRFIECYIAEQNMVSIAVGCATRNRTVPFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVSIGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAANTKGICFIRTSRPENAIIYNNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEKINIRVLDPFTIKPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRVPRSGKPAELLKMFGIDRDAIAQAVRGLITKA", "length": 623, "reference_go_mf": ["GO:0005509", "GO:0000287", "GO:0042803", "GO:0030976", "GO:0004802"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}, {"chain": "b", "status": "reference_mapping_uncertain", "selected": {"accession": "P29401", "alignment_score": 21.0, "observed_coverage": 0.048672566371681415, "aligned_identity": 0.5454545454545454, "canonical_span": [152, 185], "sequence": "MESYHKPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKSQDPRNPHNDRFVLSKGHAAPILYAVWAEAGFLAEAELLNLRKISSDLDGHPVPKQAFTDVATGSLGQGLGAACGMAYTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVAILDINRLGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDGHSVEELCKAFGQAKHQPTAIIAKTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQSKKKILATPPQEDAPSVDIANIRMPSLPSYKVGDKIATRKAYGQALAKLGHASDRIIALDGDTKNSTFSEIFKKEHPDRFIECYIAEQNMVSIAVGCATRNRTVPFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVSIGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAANTKGICFIRTSRPENAIIYNNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEKINIRVLDPFTIKPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRVPRSGKPAELLKMFGIDRDAIAQAVRGLITKA", "length": 623, "reference_go_mf": ["GO:0005509", "GO:0000287", "GO:0042803", "GO:0030976", "GO:0004802"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_220_1mcz_assembly1_reviewed_v2", "enzyme_name": "benzoylformate decarboxylase", "ec": ["4.1.1.7"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "P20906", "alignment_score": 1048.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 525], "sequence": "MASVHGTTYELLRRQGIDTVFGNPGSNELPFLKDFPEDFRYILALQEACVVGIADGYAQASRKPAFINLHSAAGTGNAMGALSNAWNSHSPLIVTAGQQTRAMIGVEALLTNVDAANLPRPLVKWSYEPASAAEVPHAMSRAIHMASMAPQGPVYLSVPYDDWDKDADPQSHHLFDRHVSSSVRLNDQDLDILVKALNSASNPAIVLGPDVDAANANADCVMLAERLKAPVWVAPSAPRCPFPTRHPCFRGLMPAGIAAISQLLEGHDVVLVIGAPVFRYHQYDPGQYLKPGTRLISVTCDPLEAARAPMGDAIVADIGAMASALANLVEESSRQLPTAAPEPAKVDQDAGRLHPETVFDTLNDMAPENAIYLNESTSTTAQMWQRLNMRNPGSYYFCAAGGLGFALPAAIGVQLAEPERQVIAVIGDGSANYSISALWTAAQYNIPTIFVIMNNGTYGALRWFAGVLEAENVPGLDVPGIDFRALAKGYGVQALKADNLEQLKGSLQEALSAKGPVLIEVSTVSPVK", "length": 528, "reference_go_mf": ["GO:0003984", "GO:0050695", "GO:0050660", "GO:0000287", "GO:0030976"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_390b6d8055a0eb4c51bb"}, "alternative_alignments": []}, {"chain": "b", "status": "assigned", "selected": {"accession": "P20906", "alignment_score": 1048.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 525], "sequence": "MASVHGTTYELLRRQGIDTVFGNPGSNELPFLKDFPEDFRYILALQEACVVGIADGYAQASRKPAFINLHSAAGTGNAMGALSNAWNSHSPLIVTAGQQTRAMIGVEALLTNVDAANLPRPLVKWSYEPASAAEVPHAMSRAIHMASMAPQGPVYLSVPYDDWDKDADPQSHHLFDRHVSSSVRLNDQDLDILVKALNSASNPAIVLGPDVDAANANADCVMLAERLKAPVWVAPSAPRCPFPTRHPCFRGLMPAGIAAISQLLEGHDVVLVIGAPVFRYHQYDPGQYLKPGTRLISVTCDPLEAARAPMGDAIVADIGAMASALANLVEESSRQLPTAAPEPAKVDQDAGRLHPETVFDTLNDMAPENAIYLNESTSTTAQMWQRLNMRNPGSYYFCAAGGLGFALPAAIGVQLAEPERQVIAVIGDGSANYSISALWTAAQYNIPTIFVIMNNGTYGALRWFAGVLEAENVPGLDVPGIDFRALAKGYGVQALKADNLEQLKGSLQEALSAKGPVLIEVSTVSPVK", "length": 528, "reference_go_mf": ["GO:0003984", "GO:0050695", "GO:0050660", "GO:0000287", "GO:0030976"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_390b6d8055a0eb4c51bb"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_220_1mcz_assembly2_reviewed_v2", "enzyme_name": "benzoylformate decarboxylase", "ec": ["4.1.1.7"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "P20906", "alignment_score": 1048.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 525], "sequence": "MASVHGTTYELLRRQGIDTVFGNPGSNELPFLKDFPEDFRYILALQEACVVGIADGYAQASRKPAFINLHSAAGTGNAMGALSNAWNSHSPLIVTAGQQTRAMIGVEALLTNVDAANLPRPLVKWSYEPASAAEVPHAMSRAIHMASMAPQGPVYLSVPYDDWDKDADPQSHHLFDRHVSSSVRLNDQDLDILVKALNSASNPAIVLGPDVDAANANADCVMLAERLKAPVWVAPSAPRCPFPTRHPCFRGLMPAGIAAISQLLEGHDVVLVIGAPVFRYHQYDPGQYLKPGTRLISVTCDPLEAARAPMGDAIVADIGAMASALANLVEESSRQLPTAAPEPAKVDQDAGRLHPETVFDTLNDMAPENAIYLNESTSTTAQMWQRLNMRNPGSYYFCAAGGLGFALPAAIGVQLAEPERQVIAVIGDGSANYSISALWTAAQYNIPTIFVIMNNGTYGALRWFAGVLEAENVPGLDVPGIDFRALAKGYGVQALKADNLEQLKGSLQEALSAKGPVLIEVSTVSPVK", "length": 528, "reference_go_mf": ["GO:0003984", "GO:0050695", "GO:0050660", "GO:0000287", "GO:0030976"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_390b6d8055a0eb4c51bb"}, "alternative_alignments": []}, {"chain": "b", "status": "assigned", "selected": {"accession": "P20906", "alignment_score": 1048.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 525], "sequence": "MASVHGTTYELLRRQGIDTVFGNPGSNELPFLKDFPEDFRYILALQEACVVGIADGYAQASRKPAFINLHSAAGTGNAMGALSNAWNSHSPLIVTAGQQTRAMIGVEALLTNVDAANLPRPLVKWSYEPASAAEVPHAMSRAIHMASMAPQGPVYLSVPYDDWDKDADPQSHHLFDRHVSSSVRLNDQDLDILVKALNSASNPAIVLGPDVDAANANADCVMLAERLKAPVWVAPSAPRCPFPTRHPCFRGLMPAGIAAISQLLEGHDVVLVIGAPVFRYHQYDPGQYLKPGTRLISVTCDPLEAARAPMGDAIVADIGAMASALANLVEESSRQLPTAAPEPAKVDQDAGRLHPETVFDTLNDMAPENAIYLNESTSTTAQMWQRLNMRNPGSYYFCAAGGLGFALPAAIGVQLAEPERQVIAVIGDGSANYSISALWTAAQYNIPTIFVIMNNGTYGALRWFAGVLEAENVPGLDVPGIDFRALAKGYGVQALKADNLEQLKGSLQEALSAKGPVLIEVSTVSPVK", "length": 528, "reference_go_mf": ["GO:0003984", "GO:0050695", "GO:0050660", "GO:0000287", "GO:0030976"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_390b6d8055a0eb4c51bb"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_223_2qf7_assembly1_reviewed_v2", "enzyme_name": "pyruvate carboxylase", "ec": ["6.4.1.1"], "controls": [{"chain": "a", "status": "reference_overlength", "selected": {"accession": "Q2K340", "alignment_score": 2082.0, "observed_coverage": 0.9990697674418605, "aligned_identity": 1.0, "canonical_span": [1, 1152], "sequence": "MPISKILVANRSEIAIRVFRAANELGIKTVAIWAEEDKLALHRFKADESYQVGRGPHLARDLGPIESYLSIDEVIRVAKLSGADAIHPGYGLLSESPEFVDACNKAGIIFIGPKADTMRQLGNKVAARNLAISVGVPVVPATEPLPDDMAEVAKMAAAIGYPVMLKASWGGGGRGMRVIRSEADLAKEVTEAKREAMAAFGKDEVYLEKLVERARHVESQILGDTHGNVVHLFERDCSVQRRNQKVVERAPAPYLSEAQRQELAAYSLKIAGATNYIGAGTVEYLMDADTGKFYFIEVNPRIQVEHTVTEVVTGIDIVKAQIHILDGAAIGTPQSGVPNQEDIRLNGHALQCRVTTEDPEHNFIPDYGRITAYRSASGFGIRLDGGTSYSGAIITRYYDPLLVKVTAWAPNPLEAISRMDRALREFRIRGVATNLTFLEAIIGHPKFRDNSYTTRFIDTTPELFQQVKRQDRATKLLTYLADVTVNGHPEAKDRPKPLENAARPVVPYANGNGVKDGTKQLLDTLGPKKFGEWMRNEKRVLLTDTTMRDGHQSLLATRMRTYDIARIAGTYSHALPNLLSLECWGGATFDVSMRFLTEDPWERLALIREGAPNLLLQMLLRGANGVGYTNYPDNVVKYFVRQAAKGGIDLFRVFDCLNWVENMRVSMDAIAEENKLCEAAICYTGDILNSARPKYDLKYYTNLAVELEKAGAHIIAVKDMAGLLKPAAAKVLFKALREATGLPIHFHTHDTSGIAAATVLAAVEAGVDAVDAAMDALSGNTSQPCLGSIVEALSGSERDPGLDPAWIRRISFYWEAVRNQYAAFESDLKGPASEVYLHEMPGGQFTNLKEQARSLGLETRWHQVAQAYADANQMFGDIVKVTPSSKVVGDMALMMVSQDLTVADVVSPDREVSFPESVVSMLKGDLGQPPSGWPEALQKKALKGEKPYTVRPGSLLKEADLDAERKVIEKKLEREVSDFEFASYLMYPKVFTDFALASDTYGPVSVLPTPAYFYGLADGEELFADIEKGKTLVIVNQAVSATDSQGMVTVFFELNGQPRRIKVPDRAHGATGAAVRRKAEPGNAAHVGAPMPGVISRVFVSSGQAVNAGDVLVSIEAMKMETAIHAEKDGTIAEVLVKAGDQIDAKDLLAVYGG", "length": 1154, "reference_go_mf": ["GO:0005524", "GO:0046872", "GO:0004736"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_242_2f9r_assembly1_reviewed_v2", "enzyme_name": "sphingomyelin phosphodiesterase D (Class I)", "ec": ["3.1.4.41"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "Q8I914", "alignment_score": 570.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [26, 311], "sequence": "MYAHLALILGCWTVVLQGAETDVGERADNRRPIWNLAHMVNAVAQIPDFLDLGANALEADVTFKGSVPTYTYHGTPCDFGRDCIRWEYFNVFLKTLREYTTPGNAKYRDGFILFVLDLKTGSLSNDQVRPAGENVAKELLQNYWNNGNNGGRAYVVLSLPDIGHYEFVRGFKEVLKKEGHEDLLEKVGYDFSGPYLPSLPTLDATHEAYKKAGVDGHIWLSDGLTNFSPLGDMARLKEAIKSRDSANGFINKIYYWSVDKVSTTKAALDVGVDGIMTNYPNVLIGVLKESGYNDKYRLATYDDNPWETFKN", "length": 311, "reference_go_mf": ["GO:0008081"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_d442b0a1b6344865b644"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_242_2f9r_assembly2_reviewed_v2", "enzyme_name": "sphingomyelin phosphodiesterase D (Class I)", "ec": ["3.1.4.41"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "Q8I914", "alignment_score": 570.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [26, 311], "sequence": "MYAHLALILGCWTVVLQGAETDVGERADNRRPIWNLAHMVNAVAQIPDFLDLGANALEADVTFKGSVPTYTYHGTPCDFGRDCIRWEYFNVFLKTLREYTTPGNAKYRDGFILFVLDLKTGSLSNDQVRPAGENVAKELLQNYWNNGNNGGRAYVVLSLPDIGHYEFVRGFKEVLKKEGHEDLLEKVGYDFSGPYLPSLPTLDATHEAYKKAGVDGHIWLSDGLTNFSPLGDMARLKEAIKSRDSANGFINKIYYWSVDKVSTTKAALDVGVDGIMTNYPNVLIGVLKESGYNDKYRLATYDDNPWETFKN", "length": 311, "reference_go_mf": ["GO:0008081"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_d442b0a1b6344865b644"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_243_1ho1_assembly1_reviewed_v2", "enzyme_name": "pyridoxine 5'-phosphate synthase", "ec": ["2.6.99.2"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "P0A794", "alignment_score": 484.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 243], "sequence": "MAELLLGVNIDHIATLRNARGTAYPDPVQAAFIAEQAGADGITVHLREDRRHITDRDVRILRQTLDTRMNLEMAVTEEMLAIAVETKPHFCCLVPEKRQEVTTEGGLDVAGQRDKMRDACKRLADAGIQVSLFIDADEEQIKAAAEVGAPFIEIHTGCYADAKTDAEQAQELARIAKAATFAASLGLKVNAGHGLTYHNVKAIAAIPEMHELNIGHAIIGRAVMTGLKDAVAEMKRLMLEARG", "length": 243, "reference_go_mf": ["GO:0042802", "GO:0033856"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_f3c1e54a5f34c4fef478"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "experimental_alternative_mapped"}
{"query_id": "mcsa_248_1a7u_assembly1_reviewed_v2", "enzyme_name": "chloride peroxidase (cofactor free)", "ec": ["1.11.1.10"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "O31168", "alignment_score": 554.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 278], "sequence": "MPFITVGQENSTSIDLYYEDHGAGQPVVLIHGFPLSGHSWERQSAALLDAGYRVITYDRRGFGQSSQPTTGYDYDTFAADLNTVLETLDLQDAVLVGFSMGTGEVARYVSSYGTARIAKVAFLASLEPFLLKTDDNPDGAAPKEFFDGIVAAVKADRYAFYTGFFNDFYNLDENLGTRISEEAVRNSWNTAASGGFFAAAAAPTTWYTDFRADIPRIDVPALILHGTGDRTLPIENTARVFHKALPSAEYVEVEGAPHGLLWTHAEEVNTALLAFLAK", "length": 278, "reference_go_mf": ["GO:0003824"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_ce677311a2537d871c5a"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_248_1a8q_assembly1_reviewed_v2", "enzyme_name": "chloride peroxidase (cofactor free)", "ec": ["1.11.1.10"], "controls": [{"chain": "a", "status": "reference_mapping_uncertain", "selected": {"accession": "O31168", "alignment_score": 73.0, "observed_coverage": 0.44525547445255476, "aligned_identity": 0.5327868852459017, "canonical_span": [17, 139], "sequence": "MPFITVGQENSTSIDLYYEDHGAGQPVVLIHGFPLSGHSWERQSAALLDAGYRVITYDRRGFGQSSQPTTGYDYDTFAADLNTVLETLDLQDAVLVGFSMGTGEVARYVSSYGTARIAKVAFLASLEPFLLKTDDNPDGAAPKEFFDGIVAAVKADRYAFYTGFFNDFYNLDENLGTRISEEAVRNSWNTAASGGFFAAAAAPTTWYTDFRADIPRIDVPALILHGTGDRTLPIENTARVFHKALPSAEYVEVEGAPHGLLWTHAEEVNTALLAFLAK", "length": 278, "reference_go_mf": ["GO:0003824"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_267_1dhp_assembly1_reviewed_v2", "enzyme_name": "dihydrodipicolinate synthase", "ec": ["4.3.3.7"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "P0A6L2", "alignment_score": 584.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 292], "sequence": "MFTGSIVAIVTPMDEKGNVCRASLKKLIDYHVASGTSAIVSVGTTGESATLNHDEHADVVMMTLDLADGRIPVIAGTGANATAEAISLTQRFNDSGIVGCLTVTPYYNRPSQEGLYQHFKAIAEHTDLPQILYNVPSRTGCDLLPETVGRLAKVKNIIGIKEATGNLTRVNQIKELVSDDFVLLSGDDASALDFMQLGGHGVISVTANVAARDMAQMCKLAAEGHFAEARVINQRLMPLHNKLFVEPNPIPVKWACKELGLVATDTLRLPMTPITDSGRETVRAALKHAGLL", "length": 292, "reference_go_mf": ["GO:0008840", "GO:0042802"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_0bce3fd79a982684b8d4"}, "alternative_alignments": []}, {"chain": "b", "status": "assigned", "selected": {"accession": "P0A6L2", "alignment_score": 584.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 292], "sequence": "MFTGSIVAIVTPMDEKGNVCRASLKKLIDYHVASGTSAIVSVGTTGESATLNHDEHADVVMMTLDLADGRIPVIAGTGANATAEAISLTQRFNDSGIVGCLTVTPYYNRPSQEGLYQHFKAIAEHTDLPQILYNVPSRTGCDLLPETVGRLAKVKNIIGIKEATGNLTRVNQIKELVSDDFVLLSGDDASALDFMQLGGHGVISVTANVAARDMAQMCKLAAEGHFAEARVINQRLMPLHNKLFVEPNPIPVKWACKELGLVATDTLRLPMTPITDSGRETVRAALKHAGLL", "length": 292, "reference_go_mf": ["GO:0008840", "GO:0042802"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_0bce3fd79a982684b8d4"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_267_1dhp_assembly2_reviewed_v2", "enzyme_name": "dihydrodipicolinate synthase", "ec": ["4.3.3.7"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "P0A6L2", "alignment_score": 584.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 292], "sequence": "MFTGSIVAIVTPMDEKGNVCRASLKKLIDYHVASGTSAIVSVGTTGESATLNHDEHADVVMMTLDLADGRIPVIAGTGANATAEAISLTQRFNDSGIVGCLTVTPYYNRPSQEGLYQHFKAIAEHTDLPQILYNVPSRTGCDLLPETVGRLAKVKNIIGIKEATGNLTRVNQIKELVSDDFVLLSGDDASALDFMQLGGHGVISVTANVAARDMAQMCKLAAEGHFAEARVINQRLMPLHNKLFVEPNPIPVKWACKELGLVATDTLRLPMTPITDSGRETVRAALKHAGLL", "length": 292, "reference_go_mf": ["GO:0008840", "GO:0042802"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_0bce3fd79a982684b8d4"}, "alternative_alignments": []}, {"chain": "b", "status": "assigned", "selected": {"accession": "P0A6L2", "alignment_score": 584.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 292], "sequence": "MFTGSIVAIVTPMDEKGNVCRASLKKLIDYHVASGTSAIVSVGTTGESATLNHDEHADVVMMTLDLADGRIPVIAGTGANATAEAISLTQRFNDSGIVGCLTVTPYYNRPSQEGLYQHFKAIAEHTDLPQILYNVPSRTGCDLLPETVGRLAKVKNIIGIKEATGNLTRVNQIKELVSDDFVLLSGDDASALDFMQLGGHGVISVTANVAARDMAQMCKLAAEGHFAEARVINQRLMPLHNKLFVEPNPIPVKWACKELGLVATDTLRLPMTPITDSGRETVRAALKHAGLL", "length": 292, "reference_go_mf": ["GO:0008840", "GO:0042802"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_0bce3fd79a982684b8d4"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_273_1jdi_assembly1_reviewed_v2", "enzyme_name": "L-ribulose-5-phosphate 4-epimerase", "ec": ["5.1.3.4"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "P08203", "alignment_score": 462.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 231], "sequence": "MLEDLKRQVLEANLALPKHNLVTLTWGNVSAVDRERGVFVIKPSGVDYSVMTADDMVVVSIETGEVVEGTKKPSSDTPTHRLLYQAFPSIGGIVHTHSRHATIWAQAGQSIPATGTTHADYFYGTIPCTRKMTDAEINGEYEWETGNVIVETFEKQGIDAAQMPGVLVHSHGPFAWGKNAEDAVHNAIVLEEVAYMGIFCRQLAPQLPDMQQTLLDKHYLRKHGAKAYYGQ", "length": 231, "reference_go_mf": ["GO:0016832", "GO:0042802", "GO:0008742", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_b6418305893dafb707f7"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "predicted", "review_disposition": "predicted_alternative_mapped"}
{"query_id": "mcsa_277_1zk7_assembly1_reviewed_v2", "enzyme_name": "mercury(II) reductase", "ec": ["1.16.1.1"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "P00392", "alignment_score": 1122.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 561], "sequence": "MTHLKITGMTCDSCAAHVKEALEKVPGVQSALVSYPKGTAQLAIVPGTSPDALTAAVAGLGYKATLADAPLADNRVGLLDKVRGWMAAAEKHSGNEPPVQVAVIGSGGAAMAAALKAVEQGAQVTLIERGTIGGTCVNVGCVPSKIMIRAAHIAHLRRESPFDGGIAATVPTIDRSKLLAQQQARVDELRHAKYEGILGGNPAITVVHGEARFKDDQSLTVRLNEGGERVVMFDRCLVATGASPAVPPIPGLKESPYWTSTEALASDTIPERLAVIGSSVVALELAQAFARLGSKVTVLARNTLFFREDPAIGEAVTAAFRAEGIEVLEHTQASQVAHMDGEFVLTTTHGELRADKLLVATGRTPNTRSLALDAAGVTVNAQGAIVIDQGMRTSNPNIYAAGDCTDQPQFVYVAAAAGTRAAINMTGGDAALDLTAMPAVVFTDPQVATVGYSEAEAHHDGIETDSRTLTLDNVPRALANFDTRGFIKLVIEEGSHRLIGVQAVAPEAGELIQTAALAIRNRMTVQELADQLFPYLTMVEGLKLAAQTFNKDVKQLSCCAG", "length": 561, "reference_go_mf": ["GO:0050660", "GO:0016152", "GO:0045340", "GO:0003955", "GO:0050661", "GO:0016668"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_c18e0bea34f43d4144f8"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "predicted", "review_disposition": "predicted_alternative_mapped"}
{"query_id": "mcsa_279_1sur_assembly1_reviewed_v2", "enzyme_name": "phosphoadenylyl-sulfate reductase (thioredoxin)", "ec": ["1.8.4.8"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "P17854", "alignment_score": 445.5, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 244], "sequence": "MSKLDLNALNELPKVDRILALAETNAELEKLDAEGRVAWALDNLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYRFIDELTDKLKLNLKVYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQSGSRANLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKHGLKYHPLWDEGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG", "length": 244, "reference_go_mf": ["GO:0004604"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_2d7eec86b1fbdb4a2f6b"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "experimental_alternative_mapped"}
{"query_id": "mcsa_284_2dd5_assembly1_reviewed_v2", "enzyme_name": "thiocyanate hydrolase", "ec": ["3.5.5.8"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "O66186", "alignment_score": 304.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [2, 154], "sequence": "MSSSIREEVHRHLGTVALMQPALHQQTHAPAPTEITHTLFRAYTRVPHDVGGEADVPIEYHEKEEEIWELNTFATCECLAWRGVWTAEERRRKQNCDVGQTVYLGMPYYGRWLLTAARILVDKQFVTLTELHNKIVEMRERVASGQGLGEYLPPKAK", "length": 157, "reference_go_mf": ["GO:0018760"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_bbc924f49b1d4c64662b"}, "alternative_alignments": [{"accession": "O66188", "alignment_score": 7.0, "observed_coverage": 0.03289473684210526, "aligned_identity": 0.8, "canonical_span": [14, 19], "length": 243, "reference_go_mf": ["GO:0018760", "GO:0046914"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, {"accession": "O66187", "alignment_score": 6.0, "observed_coverage": 0.019736842105263157, "aligned_identity": 1.0, "canonical_span": [115, 118], "length": 126, "reference_go_mf": ["GO:0018760"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}, {"chain": "b", "status": "assigned", "selected": {"accession": "O66188", "alignment_score": 420.5, "observed_coverage": 1.0, "aligned_identity": 0.9953488372093023, "canonical_span": [22, 239], "sequence": "MSADHDHDHDHDHDHKPAPMVEEVSDFEILEMAVRELAIEKGLFSAEDHRVWKDYVHTLGPLPAARLVAKAWLDPEYKKLCIEDGVEASKAVGVNWVTSPPTQFGTPSDYCNLRVLADSPTLKHVVVCTLCSCYPRPILGQSPEWYRSPNYRRRLVRWPRQVLAEFGLQLPSEVQIRVADSNQKTRYIVMPVRPEGTDGWTEDQLAEIVTRDCLIGVAVPKPGITVNAKRPVLKANRPVHHDH", "length": 243, "reference_go_mf": ["GO:0018760", "GO:0046914"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_c9380cc3f4d912d7cf3d"}, "alternative_alignments": [{"accession": "O66187", "alignment_score": 7.0, "observed_coverage": 0.023255813953488372, "aligned_identity": 0.8, "canonical_span": [100, 105], "length": 126, "reference_go_mf": ["GO:0018760"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, {"accession": "O66186", "alignment_score": 7.0, "observed_coverage": 0.023255813953488372, "aligned_identity": 0.8, "canonical_span": [113, 118], "length": 157, "reference_go_mf": ["GO:0018760"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_301_1mki_assembly1_reviewed_v2", "enzyme_name": "glutaminase", "ec": ["3.5.1.2"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "O31465", "alignment_score": 510.5, "observed_coverage": 0.9866220735785953, "aligned_identity": 0.9966101694915255, "canonical_span": [11, 327], "sequence": "MKELIKEHQKDINPALQLHDWVEYYRPFAANGQSANYIPALGKVNDSQLGICVLEPDGTMIHAGDWNVSFTMQSISKVISFIAACMSRGIPYVLDRVDVEPTGDAFNSIIRLEINKPGKPFNPMINAGALTIASILPGESAYEKLEFLYSVMETLIGKRPRIHEEVFRSEWETAHRNRALAYYLKETNFLEAEVEETLEVYLKQCAMESTTEDIALIGLILAHDGYHPIRHEQVIPKDVAKLAKALMLTCGMYNASGKYAAFVGVPAKSGVSGGIMALVPPSARREQPFQSGCGIGIYGPAIDEYGNSLTGGMLLKHMAQEWELSIF", "length": 327, "reference_go_mf": ["GO:0004359"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_36eb02c0fc1db3f9a98d"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_320_3h8i_assembly1_reviewed_v2", "enzyme_name": "sulfide:quinone oxidoreductase", "ec": ["1.8.5.4"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "Q7ZAG8", "alignment_score": 818.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 409], "sequence": "MTKVLVLGGRFGALTAAYTLKRLVGSKADVKVINKSRFSYFRPALPHVAIGVRDVDELKVDLSEALPEKGIQFQEGTVEKIDAKSSMVYYTKPDGSMAEEEYDYVIVGIGAHLATELVKGWDKYGYSVCEPEFATKLREKLESFQGGNIAIGSGPFYQGHNPKPKVPENFVPNADSACEGPVFEMSLMLHGYFKKKGMLDKVHVTVFSPGEYLSDLSPNSRKAVASIYNQLGIKLVHNFKIKEIREHEIVDEKGNTIPADITILLPPYTGNPALKNSTPDLVDDGGFIPTDLNMVSIKYDNVYAVGDANSMTVPKLGYLAVMTGRIAAQHLANRLGVPTKVDKYYPTIMCVADNPYEGYAVSVKDDTWYGGTVSIADPAAVNHLKKELFTKYYMWTKGDMALEKFLASW", "length": 409, "reference_go_mf": ["GO:0070224"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_3772af12768349e012b0"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "predicted", "review_disposition": "predicted_alternative_mapped"}
{"query_id": "mcsa_327_1i58_assembly1_reviewed_v2", "enzyme_name": "protein histidine kinase (CheA)", "ec": ["2.7.-.-"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "Q56310", "alignment_score": 1342.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 671], "sequence": "MMEEYLGVFVDETKEYLQNLNDTLLELEKNPEDMELINEAFRALHTLKGMAGTMGFSSMAKLCHTLENILDKARNSEIKITSDLLDKIFAGVDMITRMVDKIVSEGSDDIGENIDVFSDTIKSFASSGKEKPSEIKNETETKGEEEHKGESTSNEEVVVLPEEVAHVLQEARNKGFKTFYIKVILKEGTQLKSARIYLVFHKLEELKCEVVRTIPSVEEIEEEKFENEVELFVISPVDLEKLSEALSSIADIERVIIKEVTAVTEESGAEKRTEKEEKTEKTEEKAERKKVISQTVRVDIEKLDNLMDLMGELVIARSRILETLKKYNIKELDESLSHLSRITLDLQNVVMKIRMVPISFVFNRFPRMVRDLAKKMNKEVNFIMRGEDTELDRTFVEEIGEPLLHLLRNAIDHGIEPKEERIAKGKPPIGTLILSARHEGNNVVIEVEDDGRGIDKEKIIRKAIEKGLIDESKAATLSDQEILNFLFVPGFSTKEKVSEVSGRGVGMDVVKNVVESLNGSISIESEKDKGTKVTIRLPLTLAIIQALLVKVNNLVYAIPIANIDTILSISKEDIQRVQDRDVIVIRGEVIPVYRLWEVLQIEHKEELEEMEAVIVRVGNRKYGIVVDDLLGQDDIVIKSLGKVFSEVKEFSGAAILGDGSIALIINVSGIV", "length": 671, "reference_go_mf": ["GO:0000155", "GO:0019904"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_42ad2c1d5da01f09c3ff"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "predicted", "review_disposition": "predicted_alternative_mapped"}
{"query_id": "mcsa_339_1c3j_assembly1_reviewed_v2", "enzyme_name": "DNA beta-glucosyltransferase", "ec": ["2.4.1.27"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "P04547", "alignment_score": 702.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 351], "sequence": "MKIAIINMGNNVINFKTVPSSETIYLFKVISEMGLNVDIISLKNGVYTKSFDEVDVNDYDRLIVVNSSINFFGGKPNLAILSAQKFMAKYKSKIYYLFTDIRLPFSQSWPNVKNRPWAYLYTEEELLIKSPIKVISQGINLDIAKAAHKKVDNVIEFEYFPIEQYKIHMNDFQLSKPTKKTLDVIYGGSFRSGQRESKMVEFLFDTGLNIEFFGNAREKQFKNPKYPWTKAPVFTGKIPMNMVSEKNSQAIAALIIGDKNYNDNFITLRVWETMASDAVMLIDEEFDTKHRIINDARFYVNNRAELIDRVNELKHSDVLRKEMLSIQHDILNKTRAKKAEWQDAFKKAIDL", "length": 351, "reference_go_mf": ["GO:0033821"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_4abf5fae65a7f56a5b81"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "experimental_alternative_mapped"}
{"query_id": "mcsa_346_1q51_assembly1_reviewed_v2", "enzyme_name": "1,4-dihydroxy-2-naphthoyl-CoA synthase", "ec": ["4.1.3.36"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "P9WNP5", "alignment_score": 600.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [14, 314], "sequence": "MVAPAGEQGRSSTALSDNPFDAKAWRLVDGFDDLTDITYHRHVDDATVRVAFNRPEVRNAFRPHTVDELYRVLDHARMSPDVGVVLLTGNGPSPKDGGWAFCSGGDQRIRGRSGYQYASGDTADTVDVARAGRLHILEVQRLIRFMPKVVICLVNGWAAGGGHSLHVVCDLTLASREYARFKQTDADVGSFDGGYGSAYLARQVGQKFAREIFFLGRTYTAEQMHQMGAVNAVAEHAELETVGLQWAAEINAKSPQAQRMLKFAFNLLDDGLVGQQLFAGEATRLAYMTDEAVEGRDAFLQKRPPDWSPFPRYF", "length": 314, "reference_go_mf": ["GO:0008935"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_3e7ab7259d186588e92d"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "experimental_alternative_mapped"}
{"query_id": "mcsa_347_2vss_assembly1_reviewed_v2", "enzyme_name": "feruloyl CoA hydratase/lyase", "ec": ["4.-.-.-"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "O69762", "alignment_score": 491.0, "observed_coverage": 1.0, "aligned_identity": 0.9959514170040485, "canonical_span": [2, 249], "sequence": "MSTYEGRWKTVKVEIEDGIAFVILNRPEKRNAMSPTLNREMIDVLETLEQDPAAGVLVLTGAGEAWTAGMDLKEYFREVDAGPEILQEKIRREASQWQWKLLRMYAKPTIAMVNGWCFGGGFSPLVACDLAICADEATFGLSEINWGIPPGNLVSKAMADTVGHRQSLYYIMTGKTFGGQKAAEMGLVNESVPLAQLREVTIELARNLLEKNPVVLRAAKHGFKRCRELTWEQNEDYLYAKLDQSRLLDTEGGREQGMKQFLDDKSIKPGLQAYKR", "length": 276, "reference_go_mf": ["GO:0050547"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_e855187a640959c7bdea"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "experimental_alternative_mapped"}
{"query_id": "mcsa_352_3pmg_assembly1_reviewed_v2", "enzyme_name": "phosphoglucomutase", "ec": ["5.4.2.2"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "P00949", "alignment_score": 1114.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 562], "sequence": "MVKIVTVKTKAYPDQKPGTSGLRKRVKVFQSSTNYAENFIQSIISTVEPAQRQEATLVVGGDGRFYMKEAIQLIVRIAAANGIGRLVIGQNGILSTPAVSCIIRKIKAIGGIILTASHNPGGPNGDFGIKFNISNGGPAPEAITDKIFQISKTIEEYAICPDLKVDLGVLGKQQFDLENKFKPFTVEIVDSVEAYATMLRNIFDFNALKELLSGPNRLKIRIDAMHGVVGPYVKKILCEELGAPANSAVNCVPLEDFGGHHPDPNLTYAADLVETMKSGEHDFGAAFDGDGDRNMILGKHGFFVNPSDSVAVIAANIFSIPYFQQTGVRGFARSMPTSGALDRVANATKIALYETPTGWKFFGNLMDASKLSLCGEESFGTGSDHIREKDGLWAVLAWLSILATRKQSVEDILKDHWHKFGRNFFTRYDYEEVEAEGATKMMKDLEALMFDRSFVGKQFSANDKVYTVEKADNFEYHDPVDGSVSKNQGLRLIFADGSRIIFRLSGTGSAGATIRLYIDSYEKDNAKINQDPQVMLAPLISIALKVSQLQERTGRTAPTVIT", "length": 562, "reference_go_mf": ["GO:0000287", "GO:0004614"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_babc7a61715fa54546c7"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_410_1ax4_assembly1_reviewed_v2", "enzyme_name": "tryptophanase", "ec": ["4.1.99.1"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "P28796", "alignment_score": 922.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 466], "sequence": "MAKRIVEPFRIKMVEKIRVPSREEREAALKEAGYNPFLLPSSAVYIDLLTDSGTNAMSDHQWAAMITGDEAYAGSRNYYDLKDKAKELFNYDYIIPAHQGRGAENILFPVLLKYKQKEGKAKNPVFISNFHFDTTAAHVELNGCKAINIVTEKAFDSETYDDWKGDFDIKKLKENIAQHGADNIVAIVSTVTCNSAGGQPVSMSNLKEVYEIAKQHGIFVVMDSARFCENAYFIKARDPKYKNATIKEVIFDMYKYADALTMSAKKDPLLNIGGLVAIRDNEEIFTLARQRCVPMEGFVTYGGLAGRDMAAMVQGLEEGTEEEYLHYRIGQVKYLGDRLREAGIPIQYPTGGHAVFVDCKKLVPQIPGDQFPAQAVINALYLESGVRAVEIGSFLLGRDPATGEQKHADMEFMRLTIARRVYTNDHMDYIADALIGLKEKFATLKGLEFEYEPPVLRHFTARLKPIE", "length": 467, "reference_go_mf": ["GO:0009034"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_d808b4a4b3a0092978db"}, "alternative_alignments": []}, {"chain": "b", "status": "assigned", "selected": {"accession": "P28796", "alignment_score": 922.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 466], "sequence": "MAKRIVEPFRIKMVEKIRVPSREEREAALKEAGYNPFLLPSSAVYIDLLTDSGTNAMSDHQWAAMITGDEAYAGSRNYYDLKDKAKELFNYDYIIPAHQGRGAENILFPVLLKYKQKEGKAKNPVFISNFHFDTTAAHVELNGCKAINIVTEKAFDSETYDDWKGDFDIKKLKENIAQHGADNIVAIVSTVTCNSAGGQPVSMSNLKEVYEIAKQHGIFVVMDSARFCENAYFIKARDPKYKNATIKEVIFDMYKYADALTMSAKKDPLLNIGGLVAIRDNEEIFTLARQRCVPMEGFVTYGGLAGRDMAAMVQGLEEGTEEEYLHYRIGQVKYLGDRLREAGIPIQYPTGGHAVFVDCKKLVPQIPGDQFPAQAVINALYLESGVRAVEIGSFLLGRDPATGEQKHADMEFMRLTIARRVYTNDHMDYIADALIGLKEKFATLKGLEFEYEPPVLRHFTARLKPIE", "length": 467, "reference_go_mf": ["GO:0009034"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_d808b4a4b3a0092978db"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_449_1cl1_assembly1_reviewed_v2", "enzyme_name": "cystathionine beta-lyase", "ec": ["4.4.1.8"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "P06721", "alignment_score": 774.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [4, 395], "sequence": "MADKKLDTQLVNAGRSKKYTLGAVNSVIQRASSLVFDSVEAKKHATRNRANGELFYGRRGTLTHFSLQQAMCELEGGAGCVLFPCGAAAVANSILAFIEQGDHVLMTNTAYEPSQDFCSKILSKLGVTTSWFDPLIGADIVKHLQPNTKIVFLESPGSITMEVHDVPAIVAAVRSVVPDAIIMIDNTWAAGVLFKALDFGIDVSIQAATKYLVGHSDAMIGTAVCNARCWEQLRENAYLMGQMVDADTAYITSRGLRTLGVRLRQHHESSLKVAEWLAEHPQVARVNHPALPGSKGHEFWKRDFTGSSGLFSFVLKKKLNNEELANYLDNFSLFSMAYSWGGYESLILANQPEHIAAIRPQGEIDFSGTLIRLHIGLEDVDDLIADLDAGFARIV", "length": 395, "reference_go_mf": ["GO:0008784", "GO:0047804", "GO:0042802", "GO:0080146", "GO:0030170"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_c591614c703472c7dae0"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_503_4jn7_assembly1_reviewed_v2", "enzyme_name": "galactarate dehydratase (type III)", "ec": ["4.2.1.158"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "B9JNP7", "alignment_score": 790.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 395], "sequence": "MKIDRMRVFMTRDKDRPRVIVALDTDDGLTGWGECYNHGPDKALPPILDYLYGFLSGQDPTRIDYLVNLLIQQSRFPPGALGLSAISALDHCLWDLSAKAANVPVYKLLGGAVRDRVKVYAGVYTAPDAPAARDEFDRLNAEWGFTAFKLSPWRVDIHAHRWGNVVKASADYFRSLRETVRDDYEIAFDAHAQIFEPVAARQLGNALAPYDPLFYEEPLRPENIDMWGDLKQGLNCVLATGESLYNRNEFLRLLQVKGADLIQPDICVVGGISEMRRIATLAEAYFVGVAPHNPMGPLATAVNVHFSAATQNFRILEYRLPKGQAYVYGGKDIEKRQGETRYVVDPYLPKDGYLELRPDRPGWGVEMDEKAMEEEGYIHWQRRVPKRPDGSYAFA", "length": 395, "reference_go_mf": ["GO:0008867"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_f34eb8f6d2770decef57"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_505_1e0c_assembly1_reviewed_v2", "enzyme_name": "thiosulfate sulfurtransferase (prokaryotic)", "ec": ["2.8.1.1"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "P52197", "alignment_score": 534.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 271], "sequence": "MDDFASLPLVIEPADLQARLSAPELILVDLTSAARYAEGHIPGARFVDPKRTQLGQPPAPGLQPPREQLESLFGELGHRPEAVYVVYDDEGGGWAGRFIWLLDVIGQQRYHYLNGGLTAWLAEDRPLSRELPAPAGGPVALSLHDEPTASRDYLLGRLGAADLAIWDARSPQEYRGEKVLAAKGGHIPGAVNFEWTAAMDPSRALRIRTDIAGRLEELGITPDKEIVTHCQTHHRSGLTYLIAKALGYPRVKGYAGSWGEWGNHPDTPVEL", "length": 271, "reference_go_mf": ["GO:0004792"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_e7e1c8422bc5d3efce14"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_535_4pc7_assembly1_reviewed_v2", "enzyme_name": "protein-synthesizing GTPase (elongation factor Tu)", "ec": ["3.6.5.3"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "P0CE47", "alignment_score": 719.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [8, 394], "sequence": "MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAARAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQYDFPGDDTPIVRGSALKALEGDAEWEAKILELAGFLDSYIPEPERAIDKPFLLPIEDVFSISGRGTVVTGRVERGIIKVGEEVEIVGIKETQKSTCTGVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQVLAKPGTIKPHTKFESEVYILSKDEGGRHTPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGLRFAIREGGRTVGAGVVAKVLG", "length": 394, "reference_go_mf": ["GO:0005525", "GO:0003924", "GO:0097216", "GO:0000287", "GO:0003746"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_3a5811350ecb5497e4d5"}, "alternative_alignments": [{"accession": "Q7M0J8", "alignment_score": 4.0, "observed_coverage": 0.005449591280653951, "aligned_identity": 1.0, "canonical_span": [6, 8], "length": 14, "reference_go_mf": [], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_53_1d8c_assembly1_reviewed_v2", "enzyme_name": "malate synthase", "ec": ["2.3.3.9"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "P37330", "alignment_score": 1239.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [2, 722], "sequence": "MSQTITQSRLRIDANFKRFVDEEVLPGTGLDAAAFWRNFDEIVHDLAPENRQLLAERDRIQAALDEWHRSNPGPVKDKAAYKSFLRELGYLVPQPERVTVETTGIDSEITSQAGPQLVVPAMNARYALNAANARWGSLYDALYGSDIIPQEGAMVSGYDPQRGEQVIAWVRRFLDESLPLENGSYQDVVAFKVVDKQLRIQLKNGKETTLRTPAQFVGYRGDAAAPTCILLKNNGLHIELQIDANGRIGKDDPAHINDVIVEAAISTILDCEDSVAAVDAEDKILLYRNLLGLMQGTLQEKMEKNGRQIVRKLNDDRHYTAADGSEISLHGRSLLFIRNVGHLMTIPVIWDSEGNEIPEGILDGVMTGAIALYDLKVQKNSRTGSVYIVKPKMHGPQEVAFANKLFTRIETMLGMAPNTLKMGIMDEERRTSLNLRSCIAQARNRVAFINTGFLDRTGDEMHSVMEAGPMLRKNQMKSTPWIKAYERNNVLSGLFCGLRGKAQIGKGMWAMPDLMADMYSQKGDQLRAGANTAWVPSPTAATLHALHYHQTNVQSVQANIAQTEFNAEFEPLLDDLLTIPVAENANWSAQEIQQELDNNVQGILGYVVRWVEQGIGCSKVPDIHNVALMEDRATLRISSQHIANWLRHGILTKEQVQASLENMAKVVDQQNAGDPAYRPMAGNFANSCAFKAASDLIFLGVKQPNGYTEPLLHAWRLREKESH", "length": 723, "reference_go_mf": ["GO:0000287", "GO:0004474"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_b74a870150b7d53d9c14"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_53_1n8i_assembly1_reviewed_v2", "enzyme_name": "malate synthase", "ec": ["2.3.3.9"], "controls": [{"chain": "a", "status": "reference_mapping_uncertain", "selected": {"accession": "P37330", "alignment_score": 502.5, "observed_coverage": 0.9543509272467903, "aligned_identity": 0.6128550074738416, "canonical_span": [18, 713], "sequence": "MSQTITQSRLRIDANFKRFVDEEVLPGTGLDAAAFWRNFDEIVHDLAPENRQLLAERDRIQAALDEWHRSNPGPVKDKAAYKSFLRELGYLVPQPERVTVETTGIDSEITSQAGPQLVVPAMNARYALNAANARWGSLYDALYGSDIIPQEGAMVSGYDPQRGEQVIAWVRRFLDESLPLENGSYQDVVAFKVVDKQLRIQLKNGKETTLRTPAQFVGYRGDAAAPTCILLKNNGLHIELQIDANGRIGKDDPAHINDVIVEAAISTILDCEDSVAAVDAEDKILLYRNLLGLMQGTLQEKMEKNGRQIVRKLNDDRHYTAADGSEISLHGRSLLFIRNVGHLMTIPVIWDSEGNEIPEGILDGVMTGAIALYDLKVQKNSRTGSVYIVKPKMHGPQEVAFANKLFTRIETMLGMAPNTLKMGIMDEERRTSLNLRSCIAQARNRVAFINTGFLDRTGDEMHSVMEAGPMLRKNQMKSTPWIKAYERNNVLSGLFCGLRGKAQIGKGMWAMPDLMADMYSQKGDQLRAGANTAWVPSPTAATLHALHYHQTNVQSVQANIAQTEFNAEFEPLLDDLLTIPVAENANWSAQEIQQELDNNVQGILGYVVRWVEQGIGCSKVPDIHNVALMEDRATLRISSQHIANWLRHGILTKEQVQASLENMAKVVDQQNAGDPAYRPMAGNFANSCAFKAASDLIFLGVKQPNGYTEPLLHAWRLREKESH", "length": 723, "reference_go_mf": ["GO:0000287", "GO:0004474"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_569_1fuq_assembly1_reviewed_v2", "enzyme_name": "fumarate hydratase (class II)", "ec": ["4.2.1.2"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "P05042", "alignment_score": 912.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [3, 459], "sequence": "MNTVRSEKDSMGAIDVPADKLWGAQTQRSLEHFRISTEKMPTSLIHALALTKRAAAKVNEDLGLLSEEKASAIRQAADEVLAGQHDDEFPLAIWQTGSGTQSNMNMNEVLANRASELLGGVRGMERKVHPNDDVNKSQSSNDVFPTAMHVAALLALRKQLIPQLKTLTQTLNEKSRAFADIVKIGRTHLQDATPLTLGQEISGWVAMLEHNLKHIEYSLPHVAELALGGTAVGTGLNTHPEYARRVADELAVITCAPFVTAPNKFEALATCDALVQAHGALKGLAASLMKIANDVRWLASGPRCGIGEISIPENEPGSSIMPGKVNPTQCEALTMLCCQVMGNDVAINMGGASGNFELNVFRPMVIHNFLQSVRLLADGMESFNKHCAVGIEPNRERINQLLNESLMLVTALNTHIGYDKAAEIAKKAHKEGLTLKAAALALGYLSEAEFDSWVRPEQMVGSMKAGR", "length": 467, "reference_go_mf": ["GO:0004333", "GO:0042802"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_4c4cfb392311b17d88aa"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "experimental_alternative_mapped"}
{"query_id": "mcsa_57_2ahj_assembly1_reviewed_v2", "enzyme_name": "nitrile hydratase", "ec": ["4.2.1.84"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "P13448", "alignment_score": 368.5, "observed_coverage": 0.984375, "aligned_identity": 0.9947089947089947, "canonical_span": [13, 204], "sequence": "MSVTIDHTTENAAPAQAPVSDRAWALFRALDGKGLVPDGYVEGWKKTFEEDFSPRRGAELVARAWTDPEFRQLLLTDGTAAVAQYGYLGPQGEYIVAVEDTPTLKNVIVCSLCSCTAWPILGLPPTWYKSFEYRARVVREPRKVLSEMGTEIASDIEIRVYDTTAETRYMVLPQRPAGTEGWSQEQLQEIVTKDCLIGVAIPQVPTV", "length": 207, "reference_go_mf": ["GO:0018822", "GO:0046914"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_f0611bc3cb03399a2ede"}, "alternative_alignments": [{"accession": "P13449", "alignment_score": 8.0, "observed_coverage": 0.020833333333333332, "aligned_identity": 1.0, "canonical_span": [77, 81], "length": 212, "reference_go_mf": ["GO:0018822", "GO:0046914"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}, {"chain": "b", "status": "assigned", "selected": {"accession": "P13449", "alignment_score": 422.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 211], "sequence": "MDGVHDLAGVQGFGKVPHTVNADIGPTFHAEWEHLPYSLMFAGVAELGAFSVDEVRYVVERMEPRHYMMTPYYERYVIGVATLMVEKGILTQDELESLAGGPFPLSRPSESEGRPAPVETTTFEVGQRVRVRDEYVPGHIRMPAYCRGRVGTISHRTTEKWPFPDAIGHGRNDAGEEPTYHVKFAAEELFGSDTDGGSVVVDLFEGYLEPAA", "length": 212, "reference_go_mf": ["GO:0018822", "GO:0046914"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_beecdfbe855a5a468641"}, "alternative_alignments": [{"accession": "P13448", "alignment_score": 8.0, "observed_coverage": 0.018957345971563982, "aligned_identity": 1.0, "canonical_span": [196, 200], "length": 207, "reference_go_mf": ["GO:0018822", "GO:0046914"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_630_1j79_assembly1_reviewed_v2", "enzyme_name": "dihydroorotase", "ec": ["3.5.2.3"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "P05020", "alignment_score": 669.0, "observed_coverage": 1.0, "aligned_identity": 0.9912280701754386, "canonical_span": [4, 347], "sequence": "MTAPSQVLKIRRPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMPNLAPPVTTVEAAVAYRQRILDAVPAGHDFTPLMTCYLTDSLDPNELERGFNEGVFTAAKLYPANATTNSSHGVTSIDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIESVMEPLRQRLTALKVVFEHITTKDAADYVRDGNERLAATITPQHLMFNRNHMLVGGVRPHLYCLPILKRNIHQQALRELVASGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTALGSYATVFEEMNALQHFEAFCSVNGPQFYGLPVNDTFIELVREEQQVAESIALTDDTLVPFLAGETVRWSVKQ", "length": 348, "reference_go_mf": ["GO:0004151", "GO:0042803", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_6e28c37d243b8cdc2206"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_650_1qd6_assembly1_reviewed_v2", "enzyme_name": "phospholipase A1", "ec": ["3.1.1.32"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "P0A921", "alignment_score": 480.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [49, 289], "sequence": "MRTLQGWLLPVFMLPMAVYAQEATVKEVHDAPAVRGSIIANMLQEHDNPFTLYPYDTNYLIYTQTSDLNKEAIASYDWAENARKDEVKFQLSLAFPLWRGILGPNSVLGASYTQKSWWQLSNSEESSPFRETNYEPQLFLGFATDYRFAGWTLRDVEMGYNHDSNGRSDPTSRSWNRLYTRLMAENGNWLVEVKPWYVVGNTDDNPDITKYMGYYQLKIGYHLGDAVLSAKGQYNWNTGYGGAELGLSYPITKHVRLYTQVYSGYGESLIDYNFNQTRVGVGVMLNDLF", "length": 289, "reference_go_mf": ["GO:0004623", "GO:0005509", "GO:0004620", "GO:0008970", "GO:0004622", "GO:0042803"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_2b59c51a5058ff773928"}, "alternative_alignments": []}, {"chain": "b", "status": "assigned", "selected": {"accession": "P0A921", "alignment_score": 478.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [50, 289], "sequence": "MRTLQGWLLPVFMLPMAVYAQEATVKEVHDAPAVRGSIIANMLQEHDNPFTLYPYDTNYLIYTQTSDLNKEAIASYDWAENARKDEVKFQLSLAFPLWRGILGPNSVLGASYTQKSWWQLSNSEESSPFRETNYEPQLFLGFATDYRFAGWTLRDVEMGYNHDSNGRSDPTSRSWNRLYTRLMAENGNWLVEVKPWYVVGNTDDNPDITKYMGYYQLKIGYHLGDAVLSAKGQYNWNTGYGGAELGLSYPITKHVRLYTQVYSGYGESLIDYNFNQTRVGVGVMLNDLF", "length": 289, "reference_go_mf": ["GO:0004623", "GO:0005509", "GO:0004620", "GO:0008970", "GO:0004622", "GO:0042803"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_2b59c51a5058ff773928"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_707_1mt1_assembly1_reviewed_v2", "enzyme_name": "arginine decarboxylase", "ec": ["4.1.1.19"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "Q57764", "alignment_score": 330.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 165], "sequence": "MNAEINPLHAYFKLPNTVSLVAGSSEGETPLNAFDGALLNAGIGNVNLIRISSIMPPEAEIVPLPKLPMGALVPTAYGYIISDVPGETISAAISVAIPKDKSLCGLIMEYEGKCSKKEAEKTVREMAKIGFEMRGWELDRIESIAVEHTVEKLGCAFAAAALWYK", "length": 165, "reference_go_mf": ["GO:0008792"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_7a90149280e12494ee27"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "predicted", "review_disposition": "predicted_alternative_mapped"}
{"query_id": "mcsa_708_1w27_assembly1_reviewed_v2", "enzyme_name": "phenylalanine ammonia-lyase", "ec": ["4.3.1.24"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "P24481", "alignment_score": 1371.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [24, 716], "sequence": "MENGNGATTNGHVNGNGMDFCMKTEDPLYWGIAAEAMTGSHLDEVKKMVAEYRKPVVKLGGETLTISQVAAISARDGSGVTVELSEAARAGVKASSDWVMDSMNKGTDSYGVTTGFGATSHRRTKQGGALQKELIRFLNAGIFGNGSDNTLPHSATRAAMLVRINTLLQGYSGIRFEILEAITKFLNQNITPCLPLRGTITASGDLVPLSYIAGLLTGRPNSKAVGPTGVILSPEEAFKLAGVEGGFFELQPKEGLALVNGTAVGSGMASMVLFEANILAVLAEVMSAIFAEVMQGKPEFTDHLTHKLKHHPGQIEAAAIMEHILDGSAYVKAAQKLHEMDPLQKPKQDRYALRTSPQWLGPQIEVIRSSTKMIEREINSVNDNPLIDVSRNKAIHGGNFQGTPIGVSMDNTRLAIAAIGKLMFAQFSELVNDFYNNGLPSNLSGGRNPSLDYGFKGAEIAMASYCSELQFLANPVTNHVQSAEQHNQDVNSLGLISSRKTSEAVEILKLMSTTFLVGLCQAIDLRHLEENLKSTVKNTVSSVAKRVLTMGVNGELHPSRFCEKDLLRVVDREYIFAYIDDPCSATYPLMQKLRQTLVEHALKNGDNERNLSTSIFQKIATFEDELKALLPKEVESARAALESGNPAIPNRIEECRSYPLYKFVRKELGTEYLTGEKVTSPGEEFEKVFIAMSKGEIIDPLLECLESWNGAPLPIC", "length": 716, "reference_go_mf": ["GO:0016597", "GO:0045548"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_3c5206224fa4ba27a61d"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "mapped_source_annotation_conflict"}
{"query_id": "mcsa_715_1l1d_assembly1_reviewed_v2", "enzyme_name": "protein-methionine-S-oxide reductase (MsrB)", "ec": ["1.8.4.11"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "P14930", "alignment_score": 278.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [374, 521], "sequence": "MKHRTFFSLCAKFGCLLALGACSPKIVDAGTATVPHTLSTLKTADNRPASVYLKKDKPTLIKFWASWCPLCLSELGQAEKWAQDAKFSSANLITVASPGFLHEKKDGEFQKWYAGLNYPKLPVVTDNGGTIAQNLNISVYPSWALIGKDGDVQRIVKGSINEAQALALIRNPNADLGSLKHSFYKPDTQKKDSAIMNTRTIYLAGGCFWGLEAYFQRIDGVVDAVSGYANGNTENPSYEDVSYRHTGHAETVKVTYDADKLSLDDILQYYFRVVDPTSLNKQGNDTGTQYRSGVYYTDPAEKAVIAAALKREQQKYQLPLVVENEPLKNFYDAEEYHQDYLIKNPNGYCHIDIRKADEPLPGKTKAAPQGKGFDAATYKKPSDAELKRTLTEEQYQVTQNSATEYAFSHEYDHLFKPGIYVDVVSGEPLFSSADKYDSGCGWPSFTRPIDAKSVTEHDDFSFNMRRTEVRSRAADSHLGHVFPDGPRDKGGLRYCINGASLKFIPLEQMDAAGYGALKGEVK", "length": 522, "reference_go_mf": ["GO:0033744", "GO:0033743", "GO:0008113"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_ed695a4e4e5f42c199b9"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_715_1l1d_assembly2_reviewed_v2", "enzyme_name": "protein-methionine-S-oxide reductase (MsrB)", "ec": ["1.8.4.11"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "P14930", "alignment_score": 278.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [374, 521], "sequence": "MKHRTFFSLCAKFGCLLALGACSPKIVDAGTATVPHTLSTLKTADNRPASVYLKKDKPTLIKFWASWCPLCLSELGQAEKWAQDAKFSSANLITVASPGFLHEKKDGEFQKWYAGLNYPKLPVVTDNGGTIAQNLNISVYPSWALIGKDGDVQRIVKGSINEAQALALIRNPNADLGSLKHSFYKPDTQKKDSAIMNTRTIYLAGGCFWGLEAYFQRIDGVVDAVSGYANGNTENPSYEDVSYRHTGHAETVKVTYDADKLSLDDILQYYFRVVDPTSLNKQGNDTGTQYRSGVYYTDPAEKAVIAAALKREQQKYQLPLVVENEPLKNFYDAEEYHQDYLIKNPNGYCHIDIRKADEPLPGKTKAAPQGKGFDAATYKKPSDAELKRTLTEEQYQVTQNSATEYAFSHEYDHLFKPGIYVDVVSGEPLFSSADKYDSGCGWPSFTRPIDAKSVTEHDDFSFNMRRTEVRSRAADSHLGHVFPDGPRDKGGLRYCINGASLKFIPLEQMDAAGYGALKGEVK", "length": 522, "reference_go_mf": ["GO:0033744", "GO:0033743", "GO:0008113"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_ed695a4e4e5f42c199b9"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_726_1m21_assembly1_reviewed_v2", "enzyme_name": "peptide amidase", "ec": ["3.5.1.-"], "controls": [{"chain": "a", "status": "reference_mapping_uncertain", "selected": {"accession": "Q9ZIV5", "alignment_score": 31.0, "observed_coverage": 0.09034907597535935, "aligned_identity": 0.5681818181818182, "canonical_span": [117, 161], "sequence": "MISLADLQRRIETGELSPNAAIAQSHAAIEAREKEVHAFVRHDKSARAQASGPLRGIAVGIKDIIDTANMPTEMGSEIYRGWQPRSDAPVVMMLKRAGATIIGKTTTTAFASRDPTATLNPHNTGHSPGGSSSGSAAAVGAGMIPLALGTQTGGSVIRPAAYCGTAAIKPSFRMLPTVGVKCYSWALDTVGLFGARAEDLARGLLAMTGRSEFSGIVPAKAPRIGVVRQEFAGAVEPAAEQGLQAAIKAAERAGASVQAIDLPEAVHEAWRIHPIIQDFEAHRALAWEFSEHHDEIAPMLRASLDATVGLTPKEYDEARRIGRRGRRELGEVFEGVDVLLTYSAPGTAPAKALASTGDPRYNRLWTLMGNPCVNVPVLKVGGLPIGVQVIARFGNDAHALATAWFLEDALAKSG", "length": 414, "reference_go_mf": ["GO:0003824"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_726_1ocl_assembly1_reviewed_v2", "enzyme_name": "peptide amidase", "ec": ["3.5.1.-"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "Q9ZIV5", "alignment_score": 824.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 412], "sequence": "MISLADLQRRIETGELSPNAAIAQSHAAIEAREKEVHAFVRHDKSARAQASGPLRGIAVGIKDIIDTANMPTEMGSEIYRGWQPRSDAPVVMMLKRAGATIIGKTTTTAFASRDPTATLNPHNTGHSPGGSSSGSAAAVGAGMIPLALGTQTGGSVIRPAAYCGTAAIKPSFRMLPTVGVKCYSWALDTVGLFGARAEDLARGLLAMTGRSEFSGIVPAKAPRIGVVRQEFAGAVEPAAEQGLQAAIKAAERAGASVQAIDLPEAVHEAWRIHPIIQDFEAHRALAWEFSEHHDEIAPMLRASLDATVGLTPKEYDEARRIGRRGRRELGEVFEGVDVLLTYSAPGTAPAKALASTGDPRYNRLWTLMGNPCVNVPVLKVGGLPIGVQVIARFGNDAHALATAWFLEDALAKSG", "length": 414, "reference_go_mf": ["GO:0003824"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_03565afbb97e7d3f3163"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_734_2hi7_assembly1_reviewed_v2", "enzyme_name": "protein disulfide oxidoreductase", "ec": ["1.8.4.-"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "P0A6M2", "alignment_score": 352.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 176], "sequence": "MLRFLNQCSQGRGAWLLMAFTALALELTALWFQHVMLLKPCVLCIYERCALFGVLGAALIGAIAPKTPLRYVAMVIWLYSAFRGVQLTYEHTMLQLYPSPFATCDFMVRFPEWLPLDKWVPQVFVASGDCAERQWDFLGLEMPQWLLGIFIAYLIVAVLVVISQPFKAKKRDLFGR", "length": 176, "reference_go_mf": ["GO:0009055", "GO:0016672", "GO:0015035", "GO:0048039"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_1b1cdb5385ec14495a51"}, "alternative_alignments": [{"accession": "P0AEG4", "alignment_score": 8.0, "observed_coverage": 0.03977272727272727, "aligned_identity": 0.7142857142857143, "canonical_span": [111, 118], "length": 208, "reference_go_mf": ["GO:0003756", "GO:0015035"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "predicted", "review_disposition": "predicted_alternative_mapped"}
{"query_id": "mcsa_746_1qol_assembly1_reviewed_v2", "enzyme_name": "L-peptidase", "ec": ["3.4.22.46"], "controls": [{"chain": "a", "status": "reference_overlength", "selected": {"accession": "P03305", "alignment_score": 317.0, "observed_coverage": 1.0, "aligned_identity": 0.9879518072289156, "canonical_span": [28, 201], "sequence": "MNTTDCFIALVQAIREIKALFLSRTTGKMELTLYNGEKKTFYSRPNNHDNCWLNAILQLFRYVEEPFFDWVYSSPENLTLEAIKQLEDLTGLELHEGGPPALVIWNIKHLLHTGIGTASRPSEVCMVDGTDMCLADFHAGIFLKGQEHAVFACVTSNGWYAIDDEDFYPWTPDPSDVLVFVPYDQEPLNGEWKAKVQRKLKGAGQSSPATGSQNQSGNTGSIINNYYMQQYQNSMDTQLGDNAISGGSNEGSTDTTSTHTTNTQNNDWFSKLASSAFSGLFGALLADKKTEETTLLEDRILTTRNGHTTSTTQSSVGVTYGYATAEDFVSGPNTSGLETRVVQAERFFKTHLFDWVTSDSFGRCHLLELPTDHKGVYGSLTDSYAYMRNGWDVEVTAVGNQFNGGCLLVAMVPELYSIQKRELYQLTLFPHQFINPRTNMTAHITVPFVGVNRYDQYKVHKPWTLVVMVVAPLTVNTEGAPQIKVYANIAPTNVHVAGEFPSKEGIFPVACSDGYGGLVTTDPKTADPVYGKVFNPPRNQLPGRFTNLLDVAEACPTFLRFEGGVPYVTTKTDSDRVLAQFDMSLAAKQMSNTFLAGLAQYYTQYSGTINLHFMFTGPTDAKARYMVAYAPPGMEPPKTPEAAAHCIHAEWDTGLNSKFTFSIPYLSAADYAYTASGVAETTNVQGWVCLFQITHGKADGDALVVLASAGKDFELRLPVDARAETTSAGESADPVTTTVENYGGETQIQRRQHTDVSFIMDRFVKVTPQNQINILDLMQIPSHTLVGALLRASTYYFSDLEIAVKHEGDLTWVPNGAPEKALDNTTNPTAYHKAPLTRLALPYTAPHRVLATVYNGECRYNRNAVPNLRGDLQVLAQKVARTLPTSFNYGAIKATRVTELLYRMKRAETYCPRPLLAIHPTEARHKQKIVAPVKQTLNFDLLKLAGDVESNPGPFFFSDVRSNFSKLVETINQMQEDMSTKHGPDFNRLVSAFEELAIGVKAIRTGLDEAKPWYKLIKLLSRLSCMAAVAARSKDPVLVAIMLADTGLEILDSTFVVKKISDSLSSLFHVPAPVFSFGAPVLLAGLVKVASSFFRSTPEDLERAEKQLKARDINDIFAILKNGEWLVKLILAIRDWIKAWIASEEKFVTMTDLVPGILEKQRDLNDPSKYKEAKEWLDNARQACLKSGNVHIANLCKVVAPAPSKSRPEPVVVCLRGKSGQGKSFLANVLAQAISTHFTGRIDSVWYCPPDPDHFDGYNQQTVVVMDDLGQNPDGKDFKYFAQMVSTTGFIPPMASLEDKGKPFNSKVIIATTNLYSGFTPRTMVCPDALNRRFHFDIDVSAKDGYKINSKLDIIKALEDTHANPVAMFQYDCALLNGMAVEMKRMQQDMFKPQPPLQNVYQLVQEVIDRVELHEKVSSHPIFKQISIPSQKSVLYFLIEKGQHEAAIEFFEGMVHDSIKEELRPLIQQTSFVKRAFKRLKENFEIVALCLTLLANIVIMIRETRKRQKMVDDAVNEYIEKANITTDDKTLDEAEKSPLETSGASTVGFRERTLPGQKACDDVNSEPAQPVEEQPQAEGPYAGPLERQKPLKVRAKLPQQEGPYAGPMERQKPLKVKAKAPVVKEGPYEGPVKKPVALKVKAKNLIVTESGAPPTDLQKMVMGNTKPVELILDGKTVAICCATGVFGTAYLVPRHLFAEKYDKIMVDGRAMTDSDYRVFEFEIKVKGQDMLSDAALMVLHRGNRVRDITKHFRDTARMKKGTPVVGVINNADVGRLIFSGEALTYKDIVVCMDGDTMPGLFAYRAATKAGYCGGAVLAKDGADTFIVGTHSAGGNGVGYCSCVSRSMLLKMKAHIDPEPHHEGLIVDTRDVEERVHVMRKTKLAPTVAHGVFNPEFGPAALSNKDPRLNEGVVLDEVIFSKHKGDTKMSEEDKALFRRCAADYASRLHSVLGTANAPLSIYEAIKGVDGLDAMEPDTAPGLPWALQGKRRGALIDFENGTVGPEVEAALKLMEKREYKFVCQTFLKDEIRPLEKVRAGKTRIVDVLPVEHILYTRMMIGRFCAQMHSNNGPQIGSAVGCNPDVDWQRFGTHFAQYRNVWDVDYSAFDANHCSDAMNIMFEEVFRTEFGFHPNAEWILKTLVNTEHAYENKRITVGGGMPSGCSATSIINTILNNIYVLYALRRHYEGVELDTYTMISYGDDIVVASDYDLDFEALKPHFKSLGQTITPADKSDKGFVLGHSITDVTFLKRHFHMDYGTGFYKPVMASKTLEAILSFARRGTIQEKLISVAGLAVHSGPDEYRRLFEPFQGLFEIPSYRSLYLRWVNAVCGDA", "length": 2332, "reference_go_mf": ["GO:0005524", "GO:0015267", "GO:0004197", "GO:0060090", "GO:0017111", "GO:0003723", "GO:0003724", "GO:0003968", "GO:0005198"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_746_1qol_assembly2_reviewed_v2", "enzyme_name": "L-peptidase", "ec": ["3.4.22.46"], "controls": [{"chain": "a", "status": "reference_overlength", "selected": {"accession": "P03305", "alignment_score": 317.0, "observed_coverage": 1.0, "aligned_identity": 0.9879518072289156, "canonical_span": [28, 201], "sequence": "MNTTDCFIALVQAIREIKALFLSRTTGKMELTLYNGEKKTFYSRPNNHDNCWLNAILQLFRYVEEPFFDWVYSSPENLTLEAIKQLEDLTGLELHEGGPPALVIWNIKHLLHTGIGTASRPSEVCMVDGTDMCLADFHAGIFLKGQEHAVFACVTSNGWYAIDDEDFYPWTPDPSDVLVFVPYDQEPLNGEWKAKVQRKLKGAGQSSPATGSQNQSGNTGSIINNYYMQQYQNSMDTQLGDNAISGGSNEGSTDTTSTHTTNTQNNDWFSKLASSAFSGLFGALLADKKTEETTLLEDRILTTRNGHTTSTTQSSVGVTYGYATAEDFVSGPNTSGLETRVVQAERFFKTHLFDWVTSDSFGRCHLLELPTDHKGVYGSLTDSYAYMRNGWDVEVTAVGNQFNGGCLLVAMVPELYSIQKRELYQLTLFPHQFINPRTNMTAHITVPFVGVNRYDQYKVHKPWTLVVMVVAPLTVNTEGAPQIKVYANIAPTNVHVAGEFPSKEGIFPVACSDGYGGLVTTDPKTADPVYGKVFNPPRNQLPGRFTNLLDVAEACPTFLRFEGGVPYVTTKTDSDRVLAQFDMSLAAKQMSNTFLAGLAQYYTQYSGTINLHFMFTGPTDAKARYMVAYAPPGMEPPKTPEAAAHCIHAEWDTGLNSKFTFSIPYLSAADYAYTASGVAETTNVQGWVCLFQITHGKADGDALVVLASAGKDFELRLPVDARAETTSAGESADPVTTTVENYGGETQIQRRQHTDVSFIMDRFVKVTPQNQINILDLMQIPSHTLVGALLRASTYYFSDLEIAVKHEGDLTWVPNGAPEKALDNTTNPTAYHKAPLTRLALPYTAPHRVLATVYNGECRYNRNAVPNLRGDLQVLAQKVARTLPTSFNYGAIKATRVTELLYRMKRAETYCPRPLLAIHPTEARHKQKIVAPVKQTLNFDLLKLAGDVESNPGPFFFSDVRSNFSKLVETINQMQEDMSTKHGPDFNRLVSAFEELAIGVKAIRTGLDEAKPWYKLIKLLSRLSCMAAVAARSKDPVLVAIMLADTGLEILDSTFVVKKISDSLSSLFHVPAPVFSFGAPVLLAGLVKVASSFFRSTPEDLERAEKQLKARDINDIFAILKNGEWLVKLILAIRDWIKAWIASEEKFVTMTDLVPGILEKQRDLNDPSKYKEAKEWLDNARQACLKSGNVHIANLCKVVAPAPSKSRPEPVVVCLRGKSGQGKSFLANVLAQAISTHFTGRIDSVWYCPPDPDHFDGYNQQTVVVMDDLGQNPDGKDFKYFAQMVSTTGFIPPMASLEDKGKPFNSKVIIATTNLYSGFTPRTMVCPDALNRRFHFDIDVSAKDGYKINSKLDIIKALEDTHANPVAMFQYDCALLNGMAVEMKRMQQDMFKPQPPLQNVYQLVQEVIDRVELHEKVSSHPIFKQISIPSQKSVLYFLIEKGQHEAAIEFFEGMVHDSIKEELRPLIQQTSFVKRAFKRLKENFEIVALCLTLLANIVIMIRETRKRQKMVDDAVNEYIEKANITTDDKTLDEAEKSPLETSGASTVGFRERTLPGQKACDDVNSEPAQPVEEQPQAEGPYAGPLERQKPLKVRAKLPQQEGPYAGPMERQKPLKVKAKAPVVKEGPYEGPVKKPVALKVKAKNLIVTESGAPPTDLQKMVMGNTKPVELILDGKTVAICCATGVFGTAYLVPRHLFAEKYDKIMVDGRAMTDSDYRVFEFEIKVKGQDMLSDAALMVLHRGNRVRDITKHFRDTARMKKGTPVVGVINNADVGRLIFSGEALTYKDIVVCMDGDTMPGLFAYRAATKAGYCGGAVLAKDGADTFIVGTHSAGGNGVGYCSCVSRSMLLKMKAHIDPEPHHEGLIVDTRDVEERVHVMRKTKLAPTVAHGVFNPEFGPAALSNKDPRLNEGVVLDEVIFSKHKGDTKMSEEDKALFRRCAADYASRLHSVLGTANAPLSIYEAIKGVDGLDAMEPDTAPGLPWALQGKRRGALIDFENGTVGPEVEAALKLMEKREYKFVCQTFLKDEIRPLEKVRAGKTRIVDVLPVEHILYTRMMIGRFCAQMHSNNGPQIGSAVGCNPDVDWQRFGTHFAQYRNVWDVDYSAFDANHCSDAMNIMFEEVFRTEFGFHPNAEWILKTLVNTEHAYENKRITVGGGMPSGCSATSIINTILNNIYVLYALRRHYEGVELDTYTMISYGDDIVVASDYDLDFEALKPHFKSLGQTITPADKSDKGFVLGHSITDVTFLKRHFHMDYGTGFYKPVMASKTLEAILSFARRGTIQEKLISVAGLAVHSGPDEYRRLFEPFQGLFEIPSYRSLYLRWVNAVCGDA", "length": 2332, "reference_go_mf": ["GO:0005524", "GO:0015267", "GO:0004197", "GO:0060090", "GO:0017111", "GO:0003723", "GO:0003724", "GO:0003968", "GO:0005198"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_747_1l9x_assembly1_reviewed_v2", "enzyme_name": "gamma-glutamyl hydrolase", "ec": ["3.4.19.9"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "Q92820", "alignment_score": 576.0, "observed_coverage": 0.9795918367346939, "aligned_identity": 1.0, "canonical_span": [30, 318], "sequence": "MASPGCLLCVLGLLLCGAASLELSRPHGDTAKKPIIGILMQKCRNKVMKNYGRYYIAASYVKYLESAGARVVPVRLDLTEKDYEILFKSINGILFPGGSVDLRRSDYAKVAKIFYNLSIQSFDDGDYFPVWGTCLGFEELSLLISGECLLTATDTVDVAMPLNFTGGQLHSRMFQNFPTELLLSLAVEPLTANFHKWSLSVKNFTMNEKLKKFFNVLTTNTDGKIEFISTMEGYKYPVYGVQWHPEKAPYEWKNLDGISHAPNAVKTAFYLAEFFVNEARKNNHHFKSESEEEKALIYQFSPIYTGNISSFQQCYIFD", "length": 318, "reference_go_mf": ["GO:0008238", "GO:0034722", "GO:0008242"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_e3c12602cad7d058e7bc"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_747_1l9x_assembly2_reviewed_v2", "enzyme_name": "gamma-glutamyl hydrolase", "ec": ["3.4.19.9"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "Q92820", "alignment_score": 576.0, "observed_coverage": 0.9795918367346939, "aligned_identity": 1.0, "canonical_span": [30, 318], "sequence": "MASPGCLLCVLGLLLCGAASLELSRPHGDTAKKPIIGILMQKCRNKVMKNYGRYYIAASYVKYLESAGARVVPVRLDLTEKDYEILFKSINGILFPGGSVDLRRSDYAKVAKIFYNLSIQSFDDGDYFPVWGTCLGFEELSLLISGECLLTATDTVDVAMPLNFTGGQLHSRMFQNFPTELLLSLAVEPLTANFHKWSLSVKNFTMNEKLKKFFNVLTTNTDGKIEFISTMEGYKYPVYGVQWHPEKAPYEWKNLDGISHAPNAVKTAFYLAEFFVNEARKNNHHFKSESEEEKALIYQFSPIYTGNISSFQQCYIFD", "length": 318, "reference_go_mf": ["GO:0008238", "GO:0034722", "GO:0008242"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_e3c12602cad7d058e7bc"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_755_1j00_assembly1_reviewed_v2", "enzyme_name": "lysophospholipase", "ec": ["3.1.1.5"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "P0ADA1", "alignment_score": 340.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [26, 204], "sequence": "MMNFNNVFRWHLPFLFLVLLTFRAAAADTLLILGDSLSAGYRMSASAAWPALLNDKWQSKTSVVNASISGDTSQQGLARLPALLKQHQPRWVLVELGGNDGLRGFQPQQTEQTLRQILQDVKAANAEPLLMQIRLPANYGRRYNEAFSAIYPKLAKEFDVPLLPFFMEEVYLKPQWMQDDGIHPNRDAQPFIADWMAKQLQPLVNHDS", "length": 208, "reference_go_mf": ["GO:0004064", "GO:0016297", "GO:0047617", "GO:0042802", "GO:0052816", "GO:0052815", "GO:0008233", "GO:0004622"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_cb72cc0acf40ee3a2392"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_759_1cs1_assembly1_reviewed_v2", "enzyme_name": "cystathionine gamma-synthase", "ec": ["2.5.1.48"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "P00935", "alignment_score": 760.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [2, 386], "sequence": "MTRKQATIAVRSGLNDDEQYGCVVPPIHLSSTYNFTGFNEPRAHDYSRRGNPTRDVVQRALAELEGGAGAVLTNTGMSAIHLVTTVFLKPGDLLVAPHDCYGGSYRLFDSLAKRGCYRVLFVDQGDEQALRAALAEKPKLVLVESPSNPLLRVVDIAKICHLAREVGAVSVVDNTFLSPALQNPLALGADLVLHSCTKYLNGHSDVVAGVVIAKDPDVVTELAWWANNIGVTGGAFDSYLLLRGLRTLVPRMELAQRNAQAIVKYLQTQPLVKKLYHPSLPENQGHEIAARQQKGFGAMLSFELDGDEQTLRRFLGGLSLFTLAESLGGVESLISHAATMTHAGMAPEARAAAGISETLLRISTGIEDGEDLIADLENGFRAANKG", "length": 386, "reference_go_mf": ["GO:0004123", "GO:0003962", "GO:0030170"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_64e6752b0df530b6bd47"}, "alternative_alignments": []}, {"chain": "b", "status": "assigned", "selected": {"accession": "P00935", "alignment_score": 760.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [2, 386], "sequence": "MTRKQATIAVRSGLNDDEQYGCVVPPIHLSSTYNFTGFNEPRAHDYSRRGNPTRDVVQRALAELEGGAGAVLTNTGMSAIHLVTTVFLKPGDLLVAPHDCYGGSYRLFDSLAKRGCYRVLFVDQGDEQALRAALAEKPKLVLVESPSNPLLRVVDIAKICHLAREVGAVSVVDNTFLSPALQNPLALGADLVLHSCTKYLNGHSDVVAGVVIAKDPDVVTELAWWANNIGVTGGAFDSYLLLRGLRTLVPRMELAQRNAQAIVKYLQTQPLVKKLYHPSLPENQGHEIAARQQKGFGAMLSFELDGDEQTLRRFLGGLSLFTLAESLGGVESLISHAATMTHAGMAPEARAAAGISETLLRISTGIEDGEDLIADLENGFRAANKG", "length": 386, "reference_go_mf": ["GO:0004123", "GO:0003962", "GO:0030170"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_64e6752b0df530b6bd47"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_764_2f61_assembly1_reviewed_v2", "enzyme_name": "glucosylceramidase", "ec": ["3.2.1.45"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "P04062", "alignment_score": 991.0, "observed_coverage": 1.0, "aligned_identity": 0.9979879275653923, "canonical_span": [39, 536], "sequence": "MEFSSPSREECPKPLSRVSIMAGSLTGLLLLQAVSWASGARPCIPKSFGYSSVVCVCNATYCDSFDPPTFPALGTFSRYESTRSGRRMELSMGPIQANHTGTGLLLTLQPEQKFQKVKGFGGAMTDAAALNILALSPPAQNLLLKSYFSEEGIGYNIIRVPMASCDFSIRTYTYADTPDDFQLHNFSLPEEDTKLKIPLIHRALQLAQRPVSLLASPWTSPTWLKTNGAVNGKGSLKGQPGDIYHQTWARYFVKFLDAYAEHKLQFWAVTAENEPSAGLLSGYPFQCLGFTPEHQRDFIARDLGPTLANSTHHNVRLLMLDDQRLLLPHWAKVVLTDPEAAKYVHGIAVHWYLDFLAPAKATLGETHRLFPNTMLFASEACVGSKFWEQSVRLGSWDRGMQYSHSIITNLLYHVVGWTDWNLALNPEGGPNWVRNFVDSPIIVDITKDTFYKQPMFYHLGHFSKFIPEGSQRVGLVASQKNDLDAVALMHPDGSAVVVVLNRSSKDVPLTIKDPAVGFLETISPGYSIHTYLWRRQ", "length": 536, "reference_go_mf": ["GO:0008422", "GO:0004336", "GO:0004348", "GO:0046527", "GO:0005124", "GO:0005102", "GO:0050295"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_38e97d50880fc5ed6f0b"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_764_2f61_assembly2_reviewed_v2", "enzyme_name": "glucosylceramidase", "ec": ["3.2.1.45"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "P04062", "alignment_score": 991.0, "observed_coverage": 1.0, "aligned_identity": 0.9979879275653923, "canonical_span": [39, 536], "sequence": "MEFSSPSREECPKPLSRVSIMAGSLTGLLLLQAVSWASGARPCIPKSFGYSSVVCVCNATYCDSFDPPTFPALGTFSRYESTRSGRRMELSMGPIQANHTGTGLLLTLQPEQKFQKVKGFGGAMTDAAALNILALSPPAQNLLLKSYFSEEGIGYNIIRVPMASCDFSIRTYTYADTPDDFQLHNFSLPEEDTKLKIPLIHRALQLAQRPVSLLASPWTSPTWLKTNGAVNGKGSLKGQPGDIYHQTWARYFVKFLDAYAEHKLQFWAVTAENEPSAGLLSGYPFQCLGFTPEHQRDFIARDLGPTLANSTHHNVRLLMLDDQRLLLPHWAKVVLTDPEAAKYVHGIAVHWYLDFLAPAKATLGETHRLFPNTMLFASEACVGSKFWEQSVRLGSWDRGMQYSHSIITNLLYHVVGWTDWNLALNPEGGPNWVRNFVDSPIIVDITKDTFYKQPMFYHLGHFSKFIPEGSQRVGLVASQKNDLDAVALMHPDGSAVVVVLNRSSKDVPLTIKDPAVGFLETISPGYSIHTYLWRRQ", "length": 536, "reference_go_mf": ["GO:0008422", "GO:0004336", "GO:0004348", "GO:0046527", "GO:0005124", "GO:0005102", "GO:0050295"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_38e97d50880fc5ed6f0b"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_766_1s3i_assembly1_reviewed_v2", "enzyme_name": "formyltetrahydrofolate dehydrogenase", "ec": ["1.5.1.6"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "P28037", "alignment_score": 1804.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 902], "sequence": "MKIAVIGQSLFGQEVYCQLRKEGHEVVGVFTIPDKDGKADPLGLEAEKDGVPVFKFPRWRARGQALPEVVAKYQALGAELNVLPFCSQFIPMEVINAPRHGSIIYHPSLLPRHRGASAINWTLIHGDKKGGFTIFWADDGLDTGDLLLQKECEVLPDDTVSTLYNRFLFPEGIKGMVQAVRLIAEGTAPRCPQSEEGATYEGIQKKETAKINWDQPAEAIHNWIRGNDKVPGAWTEACGQKLTFFNSTLNTSGLSTQGEALPIPGAHRPGVVTKAGLILFGNDDRMLLVKNIQLEDGKMMPASQFFKGSASSDLELTEAELATAEAVRSSWMRILPNVPEVEDSTDFFKSGAASVDVVRLVEEVKELCDGLELENEDVYMATTFRGFIQLLVRKLRGEDDESECVINYVEKAVNKLTLQMPYQLFIGGEFVDAEGSKTYNTINPTDGSVICQVSLAQVSDVDKAVAAAKEAFENGLWGKINARDRGRLLYRLADVMEQHQEELATIEALDAGAVYTLALKTHVGMSIQTFRYFAGWCDKIQGATIPINQARPNRNLTLTKKEPVGVCGIVIPWNYPLMMLSWKTAACLAAGNTVVIKPAQVTPLTALKFAELTLKAGIPKGVVNILPGSGSLVGQRLSDHPDVRKIGFTGSTEVGKHIMKSCALSNVKKVSLELGGKSPLIIFADCDLNKAVQMGMSSVFFNKGENCIAAGRLFVEESIHNQFVQKVVEEVEKMKIGNPLERDTNHGPQNHEAHLRKLVEYCQRGVKEGATLVCGGNQVPRPGFFFQPTVFTDVEDHMYIAKEESFGPIMIISRFADGDVDAVLSRANATEFGLASGVFTRDINKALYVSDKLQAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGEAALNEYLRIKTVTFEY", "length": 902, "reference_go_mf": ["GO:0004029", "GO:0033721", "GO:0004030", "GO:0016155", "GO:0044877"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_e9083d4b047cf72b001f"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "predicted", "review_disposition": "predicted_alternative_mapped"}
{"query_id": "mcsa_787_1t0u_assembly1_reviewed_v2", "enzyme_name": "uridine phosphorylase", "ec": ["2.4.2.3"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "P12758", "alignment_score": 436.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [3, 253], "sequence": "MSKSDVFHLGLTKNDLQGATLAIVPGDPDRVEKIAALMDKPVKLASHREFTTWRAELDGKPVIVCSTGIGGPSTSIAVEELAQLGIRTFLRIGTTGAIQPHINVGDVLVTTASVRLDGASLHFAPLEFPAVADFECTTALVEAAKSIGATTHVGVTASSDTFYPGQERYDTYSGRVVRHFKGSMEEWQAMGVMNYEMESATLLTMCASQGLRAGMVAGVIVNRTQQEIPNAETMKQTESHAVKIVVEAARRLL", "length": 253, "reference_go_mf": ["GO:0005524", "GO:0042802", "GO:0030955", "GO:0004850"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_35b945080f1215d12aca"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "experimental_alternative_mapped"}
{"query_id": "mcsa_797_1rba_assembly1_reviewed_v2", "enzyme_name": "ribulose-bisphosphate carboxylase (type II)", "ec": ["4.1.1.39"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "P04718", "alignment_score": 868.5, "observed_coverage": 1.0, "aligned_identity": 0.9977477477477478, "canonical_span": [2, 457], "sequence": "MDQSSRYVNLALKEEDLIAGGEHVLCAYIMKPKAGYGYVATAAHFAAESSTGTNVEVCTTDDFTRGVDALVYEVDEARELTKIAYPVALFHRNITDGKAMIASFLTLTMGNNQGMGDVEYAKMHDFYVPEAYRALFDGPSVNISALWKVLGRPEVDGGLVVGTIIKPKLGLRPKPFAEACHAFWLGGDFIKNDEPQGNQPFAPLRDTIALVADAMRRAQDETGEAKLFSANITADDPFEIIARGEYVLETFGENASHVALLVDGYVAGAAAITTARRRFPDNFLHYHRAGHGAVTSPQSKRGYTAFVHCKMARLQGASGIHTGTMGFGKMEGESSDRAIAYMLTQDEAQGPFYRQSWGGMKACTPIISGGMNALRMPGFFENLGNANVILTAGGGAFGHIDGPVAGARSLRQAWQAWRDGVPVLDYAREHKELARAFESFPGDADQIYPGWRKALGVEDTRSALPA", "length": 466, "reference_go_mf": ["GO:0000287", "GO:0016984"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_b16d90eb637d55559a6b"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "experimental_alternative_mapped"}
{"query_id": "mcsa_800_1h7x_assembly1_reviewed_v2", "enzyme_name": "dihydropyrimidine dehydrogenase (NADP+)", "ec": ["1.3.1.2"], "controls": [{"chain": "a", "status": "reference_overlength", "selected": {"accession": "Q28943", "alignment_score": 2032.0, "observed_coverage": 1.0, "aligned_identity": 0.9980372914622179, "canonical_span": [1, 1020], "sequence": "MAPVLSKDVADIESILALNPRTQSHAALHSTLAKKLDKKHWKRNPDKNCFHCEKLENNFDDIKHTTLGERGALREAMRCLKCADAPCQKSCPTHLDIKSFITSISNKNYYGAAKMIFSDNPLGLTCGMVCPTSDLCVGGCNLYATEEGSINIGGLQQFASEVFKAMNIPQIRNPCLPSQEKMPEAYSAKIALLGAGPASISCASFLARLGYSDITIFEKQEYVGGLSTSEIPQFRLPYDVVNFEIELMKDLGVKIICGKSLSENEITLNTLKEEGYKAAFIGIGLPEPKTDDIFQGLTQDQGFYTSKDFLPLVAKSSKAGMCACHSPLPSIRGAVIVLGAGDTAFDCATSALRCGARRVFLVFRKGFVNIRAVPEEVELAKEEKCEFLPFLSPRKVIVKGGRIVAVQFVRTEQDETGKWNEDEDQIVHLKADVVISAFGSVLRDPKVKEALSPIKFNRWDLPEVDPETMQTSEPWVFAGGDIVGMANTTVESVNDGKQASWYIHKYIQAQYGASVSAKPELPLFYTPVDLVDISVEMAGLKFINPFGLASAAPTTSSSMIRRAFEAGWGFALTKTFSLDKDIVTNVSPRIVRGTTSGPMYGPGQSSFLNIELISEKTAAYWCQSVTELKADFPDNIVIASIMCSYNKNDWMELSRKAEASGADALELNLSCPHGMGERGMGLACGQDPELVRNICRWVRQAVQIPFFAKLTPNVTDIVSIARAAKEGGADGVTATNTVSGLMGLKADGTPWPAVGAGKRTTYGGVSGTAIRPIALRAVTTIARALPGFPILATGGIDSAESGLQFLHSGASVLQVCSAVQNQDFTVIQDYCTGLKALLYLKSIEELQGWDGQSPGTESHQKGKPVPRIAELMGKKLPNFGPYLEQRKKIIAEEKMRLKEQNAAFPPLERKPFIPKKPIPAIKDVIGKALQYLGTFGELSNIEQVVAVIDEEMCINCGKCYMTCNDSGYQAIQFDSETHLPTVTDTCTGCTLCLSVCPIIDCIRMVSRTTPYEPKRGLPLAVNPVC", "length": 1025, "reference_go_mf": ["GO:0017113", "GO:0050660", "GO:0010181", "GO:0051536", "GO:0050661", "GO:0042803", "GO:0002058"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_800_1h7x_assembly2_reviewed_v2", "enzyme_name": "dihydropyrimidine dehydrogenase (NADP+)", "ec": ["1.3.1.2"], "controls": [{"chain": "a", "status": "reference_overlength", "selected": {"accession": "Q28943", "alignment_score": 2032.0, "observed_coverage": 1.0, "aligned_identity": 0.9980372914622179, "canonical_span": [1, 1020], "sequence": "MAPVLSKDVADIESILALNPRTQSHAALHSTLAKKLDKKHWKRNPDKNCFHCEKLENNFDDIKHTTLGERGALREAMRCLKCADAPCQKSCPTHLDIKSFITSISNKNYYGAAKMIFSDNPLGLTCGMVCPTSDLCVGGCNLYATEEGSINIGGLQQFASEVFKAMNIPQIRNPCLPSQEKMPEAYSAKIALLGAGPASISCASFLARLGYSDITIFEKQEYVGGLSTSEIPQFRLPYDVVNFEIELMKDLGVKIICGKSLSENEITLNTLKEEGYKAAFIGIGLPEPKTDDIFQGLTQDQGFYTSKDFLPLVAKSSKAGMCACHSPLPSIRGAVIVLGAGDTAFDCATSALRCGARRVFLVFRKGFVNIRAVPEEVELAKEEKCEFLPFLSPRKVIVKGGRIVAVQFVRTEQDETGKWNEDEDQIVHLKADVVISAFGSVLRDPKVKEALSPIKFNRWDLPEVDPETMQTSEPWVFAGGDIVGMANTTVESVNDGKQASWYIHKYIQAQYGASVSAKPELPLFYTPVDLVDISVEMAGLKFINPFGLASAAPTTSSSMIRRAFEAGWGFALTKTFSLDKDIVTNVSPRIVRGTTSGPMYGPGQSSFLNIELISEKTAAYWCQSVTELKADFPDNIVIASIMCSYNKNDWMELSRKAEASGADALELNLSCPHGMGERGMGLACGQDPELVRNICRWVRQAVQIPFFAKLTPNVTDIVSIARAAKEGGADGVTATNTVSGLMGLKADGTPWPAVGAGKRTTYGGVSGTAIRPIALRAVTTIARALPGFPILATGGIDSAESGLQFLHSGASVLQVCSAVQNQDFTVIQDYCTGLKALLYLKSIEELQGWDGQSPGTESHQKGKPVPRIAELMGKKLPNFGPYLEQRKKIIAEEKMRLKEQNAAFPPLERKPFIPKKPIPAIKDVIGKALQYLGTFGELSNIEQVVAVIDEEMCINCGKCYMTCNDSGYQAIQFDSETHLPTVTDTCTGCTLCLSVCPIIDCIRMVSRTTPYEPKRGLPLAVNPVC", "length": 1025, "reference_go_mf": ["GO:0017113", "GO:0050660", "GO:0010181", "GO:0051536", "GO:0050661", "GO:0042803", "GO:0002058"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_838_1znv_assembly1_reviewed_v2", "enzyme_name": "Colicin-E7", "ec": ["3.1.-.-"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "Q47112", "alignment_score": 254.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [446, 573], "sequence": "MSGGDGRGHNSGAHNTGGNINGGPTGLGGNGGASDGSGWSSENNPWGGGSGSGVHWGGGSGHGNGGGNSNSGGGSNSSVAAPMAFGFPALAAPGAGTLGISVSGEALSAAIADIFAALKGPFKFSAWGIALYGILPSEIAKDDPNMMSKIVTSLPAETVTNVQVSTLPLDQATVSVTKRVTDVVKDTRQHIAVVAGVPMSVPVVNAKPTRTPGVFHASFPGVPSLTVSTVKGLPVSTTLPRGITEDKGRTAVPAGFTFGGGSHEAVIRFPKESGQKPVYVSVTDVLTPAQVKQRQDEEKRLQQEWNDAHPVEVAERNYEQARAELNQANKDVARNQERQAKAVQVYNSRKSELDAANKTLADAKAEIKQFERFAREPMAAGHRMWQMAGLKAQRAQTDVNNKKAAFDAAAKEKSDADVALSSALERRKQKENKEKDAKAKLDKESKRNKPGKATGKGKPVNNKWLNNAGKDLGSPVPDRIANKLRDKEFKSFDDFRKKFWEEVSKDPELSKQFSRNNNDRMKVGKAPKTRTQDVSGKRTSFELHHEKPISQNGGVYDMDNISVVTPKRHIDIHRGK", "length": 576, "reference_go_mf": ["GO:0004519"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_b53aa75a455e9cfc48fc"}, "alternative_alignments": [{"accession": "Q03708", "alignment_score": 6.0, "observed_coverage": 0.023622047244094488, "aligned_identity": 1.0, "canonical_span": [80, 83], "length": 87, "reference_go_mf": ["GO:0015643"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "experimental_alternative_mapped"}
{"query_id": "mcsa_864_1oac_assembly1_reviewed_v2", "enzyme_name": "primary-amine oxidase", "ec": ["1.4.3.21"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "P46883", "alignment_score": 1432.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [34, 754], "sequence": "MGSPSLYSARKTTLALAVALSFAWQAPVFAHGGEAHMVPMDKTLKEFGADVQWDDYAQLFTLIKDGAYVKVKPGAQTAIVNGQPLALQVPVVMKDNKAWVSDTFINDVFQSGLDQTFQVEKRPHPLNALTADEIKQAVEIVKASADFKPNTRFTEISLLPPDKEAVWAFALENKPVDQPRKADVIMLDGKHIIEAVVDLQNNKLLSWQPIKDAHGMVLLDDFASVQNIINNSEEFAAAVKKRGITDAKKVITTPLTVGYFDGKDGLKQDARLLKVISYLDVGDGNYWAHPIENLVAVVDLEQKKIVKIEEGPVVPVPMTARPFDGRDRVAPAVKPMQIIEPEGKNYTITGDMIHWRNWDFHLSMNSRVGPMISTVTYNDNGTKRKVMYEGSLGGMIVPYGDPDIGWYFKAYLDSGDYGMGTLTSPIARGKDAPSNAVLLNETIADYTGVPMEIPRAIAVFERYAGPEYKHQEMGQPNVSTERRELVVRWISTVGNYDYIFDWIFHENGTIGIDAGATGIEAVKGVKAKTMHDETAKDDTRYGTLIDHNIVGTTHQHIYNFRLDLDVDGENNSLVAMDPVVKPNTAGGPRTSTMQVNQYNIGNEQDAAQKFDPGTIRLLSNPNKENRMGNPVSYQIIPYAGGTHPVAKGAQFAPDEWIYHRLSFMDKQLWVTRYHPGERFPEGKYPNRSTHDTGLGQYSKDNESLDNTDAVVWMTTGTTHVARAEEWPIMPTEWVHTLLKPWNFFDETPTLGALKKDK", "length": 757, "reference_go_mf": ["GO:0005509", "GO:0005507", "GO:0008131", "GO:0048038"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_464d21e80617bf1c8b47"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_867_1xw6_assembly1_reviewed_v2", "enzyme_name": "Glutathione S-transferase class-\u03bc", "ec": ["2.5.1.18"], "controls": [{"chain": "a", "status": "reference_mapping_uncertain", "selected": {"accession": "P30114", "alignment_score": 15.0, "observed_coverage": 0.0967741935483871, "aligned_identity": 0.5714285714285714, "canonical_span": [70, 91], "sequence": "MTGDHIKVIYFNGRGRAESIRMTLVAAGVNYEDERISFQDWPKIKPTIPGGRLPAVKITDNHGHVKWMLESLAIARYMAKKHHMMGETDEEYYNVEKLIGQVEDLEHEYHKTLMKPEEEKQKITKEILNGKVPVLLDIICESLKASTGKLAVGDKVTLADLVLIAVIDHVTDLDKEFLTGKYPEIHKHRENLLASSPRLAKYLSDRAATPF", "length": 211, "reference_go_mf": ["GO:0004364"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_870_1oh9_assembly1_reviewed_v2", "enzyme_name": "acetylglutamate kinase", "ec": ["2.7.2.8"], "controls": [{"chain": "a", "status": "reference_mapping_uncertain", "selected": {"accession": "Q9SCL7", "alignment_score": 31.0, "observed_coverage": 0.1821705426356589, "aligned_identity": 0.5957446808510638, "canonical_span": [223, 271], "sequence": "MATVTSNASPKSFSFTVSNPFKTLIPNKSPSLCYPTRNKNHHRLGFSIKATVSTPPSIATGNAPSPDYRVEILSESLPFIQKFRGKTIVVKYGGAAMTSPELKSSVVSDLVLLACVGLRPILVHGGGPDINRYLKQLNIPAEFRDGLRVTDATTMEIVSMVLVGKVNKNLVSLINAAGATAVGLSGHDGRLLTARPVPNSAQLGFVGEVARVDPSVLRPLVDYGYIPVIASVAADDSGQAYNINADTVAGELAAALGAEKLILLTDVAGILENKEDPSSLIKEIDIKGVKKMIEDGKVAGGMIPKVKCCIRSLAQGVKTASIIDGRRQHSLLHEIMSDEGAGTMITG", "length": 347, "reference_go_mf": ["GO:0003991", "GO:0034618", "GO:0005524"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_870_4usj_assembly1_reviewed_v2", "enzyme_name": "acetylglutamate kinase", "ec": ["2.7.2.8"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "Q9SCL7", "alignment_score": 562.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [66, 347], "sequence": "MATVTSNASPKSFSFTVSNPFKTLIPNKSPSLCYPTRNKNHHRLGFSIKATVSTPPSIATGNAPSPDYRVEILSESLPFIQKFRGKTIVVKYGGAAMTSPELKSSVVSDLVLLACVGLRPILVHGGGPDINRYLKQLNIPAEFRDGLRVTDATTMEIVSMVLVGKVNKNLVSLINAAGATAVGLSGHDGRLLTARPVPNSAQLGFVGEVARVDPSVLRPLVDYGYIPVIASVAADDSGQAYNINADTVAGELAAALGAEKLILLTDVAGILENKEDPSSLIKEIDIKGVKKMIEDGKVAGGMIPKVKCCIRSLAQGVKTASIIDGRRQHSLLHEIMSDEGAGTMITG", "length": 347, "reference_go_mf": ["GO:0003991", "GO:0034618", "GO:0005524"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_f50adb24004f25117fc4"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_871_1okg_assembly1_reviewed_v2", "enzyme_name": "3-mercaptopyruvate sulfurtransferase", "ec": ["2.8.1.2"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "Q7K9G0", "alignment_score": 586.0, "observed_coverage": 0.9913544668587896, "aligned_identity": 0.9854651162790697, "canonical_span": [6, 370], "sequence": "MSAPAAAPKHPGKVFLDPSEVKDHLAEYRIVDCRYSLKIKDHGSIQYAKEHVKSAIRADVDTNLSKLVPTSTARHPLPPCAEFIDWCMANGMAGELPVLCYDDECGAMGGCRLWWMLNSLGADAYVINGGFQACKAAGLEMESGEPSSLPRPATHWPFKTAFQHHYLVDEIPPNAIITDARSADRFASTVRPYAADKMPGHIEGARNLPYTSHLVTRGDGKVLRSEEEIRHNIMTVVQGAGDAADLSSFVFSCGSGVTACINIALVHHLGLGHPYLYCGSWSEYSGLFRPPIMRSIIDDYGMCMQMQTPSLGDNPKANLDTMTLKVDGAPCERPDAEVQSAATHLHAGEAATVYFKSGRVVTIEVPAVPN", "length": 370, "reference_go_mf": ["GO:0016784"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_9e84f94b98d79b2ec977"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_87_1fwj_assembly1_reviewed_v2", "enzyme_name": "urease", "ec": ["3.5.1.5"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "P18314", "alignment_score": 1124.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 567], "sequence": "MSNISRQAYADMFGPTVGDKVRLADTELWIEVEDDLTTYGEEVKFGGGKVIRDGMGQGQMLAADCVDLVLTNALIVDHWGIVKADIGVKDGRIFAIGKAGNPDIQPNVTIPIGAATEVIAAEGKIVTAGGIDTHIHWICPQQAEEALVSGVTTMVGGGTGPAAGTHATTCTPGPWYISRMLQAADSLPVNIGLLGKGNVSQPDALREQVAAGVIGLKIHEDWGATPAAIDCALTVADEMDIQVALHSDTLNESGFVEDTLAAIGGRTIHTFHTEGAGGGHAPDIITACAHPNILPSSTNPTLPYTLNTIDEHLDMLMVCHHLDPDIAEDVAFAESRIRRETIAAEDVLHDLGAFSLTSSDSQAMGRVGEVILRTWQVAHRMKVQRGALAEETGDNDNFRVKRYIAKYTINPALTHGIAHEVGSIEVGKLADLVVWSPAFFGVKPATVIKGGMIAIAPMGDINASIPTPQPVHYRPMFGALGSARHHCRLTFLSQAAAANGVAERLNLRSAIAVVKGCRTVQKADMVHNSLQPNITVDAQTYEVRVDGELITSEPADVLPMAQRYFLF", "length": 567, "reference_go_mf": ["GO:0016151", "GO:0009039"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_f1b11f1604dca538e1ed"}, "alternative_alignments": [{"accession": "P18316", "alignment_score": 10.0, "observed_coverage": 0.01415929203539823, "aligned_identity": 0.75, "canonical_span": [65, 73], "length": 100, "reference_go_mf": ["GO:0016151", "GO:0009039"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, {"accession": "P18315", "alignment_score": 9.0, "observed_coverage": 0.010619469026548672, "aligned_identity": 0.8333333333333334, "canonical_span": [79, 85], "length": 106, "reference_go_mf": ["GO:0009039"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}]}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_895_2npx_assembly1_reviewed_v2", "enzyme_name": "NADH peroxidase", "ec": ["1.11.1.1"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "P37062", "alignment_score": 883.0, "observed_coverage": 1.0, "aligned_identity": 0.9977578475336323, "canonical_span": [0, 447], "sequence": "MKVIVLGSSHGGYEAVEELLNLHPDAEIQWYEKGDFISFLSCGMQLYLEGKVKDVNSVRYMTGEKMESRGVNVFSNTEITAIQPKEHQVTVKDLVSGEERVENYDKLIISPGAVPFELDIPGKDLDNIYLMRGRQWAIKLKQKTVDPEVNNVVVIGSGYIGIEAAEAFAKAGKKVTVIDILDRPLGVYLDKEFTDVLTEEMEANNITIATGETVERYEGDGRVQKIVTDKNAYDADLVVVAVGVRPNTAWLKGTLELHPNGLIKTDEYMRTSEPDVFAVGDATLIKYNPADTEVNIALATNARKQGRFAVKNLEEPVKPFPGVQGSSGLAVFDYKFASTGINEVMAQKLGKETKAVTVVEDYLMDFNPDKQKAWFKLVYDPETTQILGAQLMSKADLTANINAISLAIQAKMTIEDLAYADFFFQPAFDKPWNIINTAALEAVKQER", "length": 447, "reference_go_mf": ["GO:0016692"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_da3e7330520fa81074d5"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_920_2hwg_assembly1_reviewed_v2", "enzyme_name": "phosphoenolpyruvate---protein phosphotransferase", "ec": ["2.7.3.9"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "P08839", "alignment_score": 1000.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [1, 573], "sequence": "MISGILASPGIAFGKALLLKEDEIVIDRKKISADQVDQEVERFLSGRAKASAQLETIKTKAGETFGEEKEAIFEGHIMLLEDEELEQEIIALIKDKHMTADAAAHEVIEGQASALEELDDEYLKERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVAADLTPSETAQLNLKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYLILDAVNNQVYVNPTNEVIDKMRAVQEQVASEKAELAKLKDLPAITLDGHQVEVCANIGTVRDVEGAERNGAEGVGLYRTEFLFMDRDALPTEEEQFAAYKAVAEACGSQAVIVRTMDIGGDKELPYMNFPKEENPFLGWRAIRIAMDRREILRDQLRAILRASAFGKLRIMFPMIISVEEVRALRKEIEIYKQELRDEGKAFDESIEIGVMVETPAAATIARHLAKEVDFFSIGTNDLTQYTLAVDRGNDMISHLYQPMSPSVLNLIKQVIDASHAEGKWTGMCGELAGDERATLLLLGMGLDEFSMSAISIPRIKKIIRNTNFEDAKVLAEQALAQPTTDELMTLVNKFIEEKTIC", "length": 575, "reference_go_mf": ["GO:0042802", "GO:0008965"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_f47c389083b6edc0b110"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_933_2tpl_assembly1_reviewed_v2", "enzyme_name": "tyrosine phenol-lyase", "ec": ["4.1.99.2"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "P31013", "alignment_score": 899.0, "observed_coverage": 1.0, "aligned_identity": 0.9977973568281938, "canonical_span": [1, 456], "sequence": "MNYPAEPFRIKSVETVSMIPRDERLKKMQEAGYNTFLLNSKDIYIDLLTDSGTNAMSDKQWAGMMMGDEAYAGSENFYHLERTVQELFGFKHIVPTHQGRGAENLLSQLAIKPGQYVAGNMYFTTTRYHQEKNGAVFVDIVRDEAHDAGLNIAFKGDIDLKKLQKLIDEKGAENIAYICLAVTVNLAGGQPVSMANMRAVRELTEAHGIKVFYDATRCVENAYFIKEQEQGFENKSIAEIVHEMFSYADGCTMSGKKDCLVNIGGFLCMNDDEMFSSAKELVVVYEGMPSYGGLAGRDMEAMAIGLREAMQYEYIEHRVKQVRYLGDKLKAAGVPIVEPVGGHAVFLDARRFCEHLTQDEFPAQSLAASIYVETGVRSMERGIISAGRNNVTGEHHRPKLETVRLTIPRRVYTYAHMDVVADGIIKLYQHKEDIRGLKFIYEPKQLRFFTARFDYI", "length": 456, "reference_go_mf": ["GO:0050371"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_42490cdd8db1f9831aa9"}, "alternative_alignments": []}, {"chain": "b", "status": "assigned", "selected": {"accession": "P31013", "alignment_score": 899.0, "observed_coverage": 1.0, "aligned_identity": 0.9977973568281938, "canonical_span": [1, 456], "sequence": "MNYPAEPFRIKSVETVSMIPRDERLKKMQEAGYNTFLLNSKDIYIDLLTDSGTNAMSDKQWAGMMMGDEAYAGSENFYHLERTVQELFGFKHIVPTHQGRGAENLLSQLAIKPGQYVAGNMYFTTTRYHQEKNGAVFVDIVRDEAHDAGLNIAFKGDIDLKKLQKLIDEKGAENIAYICLAVTVNLAGGQPVSMANMRAVRELTEAHGIKVFYDATRCVENAYFIKEQEQGFENKSIAEIVHEMFSYADGCTMSGKKDCLVNIGGFLCMNDDEMFSSAKELVVVYEGMPSYGGLAGRDMEAMAIGLREAMQYEYIEHRVKQVRYLGDKLKAAGVPIVEPVGGHAVFLDARRFCEHLTQDEFPAQSLAASIYVETGVRSMERGIISAGRNNVTGEHHRPKLETVRLTIPRRVYTYAHMDVVADGIIKLYQHKEDIRGLKFIYEPKQLRFFTARFDYI", "length": 456, "reference_go_mf": ["GO:0050371"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_42490cdd8db1f9831aa9"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": false, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_938_3rfa_assembly1_reviewed_v2", "enzyme_name": "adenosine C2 methyltransferase (RlmN)", "ec": ["2.1.1.192"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "P36979", "alignment_score": 710.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [16, 375], "sequence": "MSEQLVTPENVTTKDGKINLLDLNRQQMREFFKDLGEKPFRADQVMKWMYHYCCDNFDEMTDINKVLRGKLKEVAEIRAPEVVEEQRSSDGTIKWAIAVGDQRVETVYIPEDDRATLCVSSQVGCALECKFCSTAQQGFNRNLRVSEIIGQVWRAAKIVGAAKVTGQRPITNVVMMGMGEPLLNLNNVVPAMEIMLDDFGFGLSKRRVTLSTSGVVPALDKLGDMIDVALAISLHAPNDEIRDEIVPINKKYNIETFLAAVRRYLEKSNANQGRVTIEYVMLDHVNDGTEHAHQLAELLKDTPCKINLIPWNPFPGAPYGRSSNSRIDRFSKVLMSYGFTTIVRKTRGDDIDAACGQLAGDVIDRTKRTLRKRMQGEAIDIKAV", "length": 384, "reference_go_mf": ["GO:0051539", "GO:0070040", "GO:0019843", "GO:0002935", "GO:0000049"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_dad7cadf941731cf2b19"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_984_4e5k_assembly1_reviewed_v2", "enzyme_name": "phosphonate dehydrogenase", "ec": ["1.20.1.1"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "O69054", "alignment_score": 616.0, "observed_coverage": 1.0, "aligned_identity": 0.9574468085106383, "canonical_span": [0, 329], "sequence": "MLPKLVITHRVHDEILQLLAPHCELMTNQTDSTLTREEILRRCRDAQAMMAFMPDRVDADFLQACPELRVVGCALKGFDNFDVDACTARGVWLTFVPDLLTVPTAELAIGLAVGLGRHLRAADAFVRSGEFQGWQPQFYGTGLDNATVGILGMGAIGLAMADRLQGWGATLQYHEAKALDTQTEQRLGLRQVACSELFASSDFILLALPLNADTQHLVNAELLALVRPGALLVNPCRGSVVDEAAVLAALERGQLGGYAADVFEMEDWARADRPRLIDPALLAHPNTLFTPHIGSAVRAVRLEIERCAAQNIIQVLAGARPINAANRLPKAEPAAC", "length": 336, "reference_go_mf": ["GO:0030267", "GO:0008465", "GO:0051287", "GO:0050609"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_6e8a7b5e0ea2e20ac9ef"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_985_5my0_assembly1_reviewed_v2", "enzyme_name": "acyl-carrier-protein S-acetyltransferase", "ec": ["2.3.1.38"], "controls": [{"chain": "a", "status": "reference_overlength", "selected": {"accession": "P19096", "alignment_score": 1686.5, "observed_coverage": 0.9988207547169812, "aligned_identity": 1.0, "canonical_span": [1, 852], "sequence": "MEEVVIAGMSGKLPESENLQEFWANLIGGVDMVTDDDRRWKAGLYGLPKRSGKLKDLSKFDASFFGVHPKQAHTMDPQLRLLLEVSYEAIVDGGINPASLRGTNTGVWVGVSGSEASEALSRDPETLLGYSMVGCQRAMMANRLSFFFDFKGPSIALDTACSSSLLALQNAYQAIRSGECPAALVGGINLLLKPNTSVQFMKLGMLSPDGTCRSFDDSGSGYCRSEAVVAVLLTKKSLARRVYATILNAGTNTDGSKEQGVTFPSGEVQEQLICSLYQPAGLAPESLEYIEAHGTGTKVGDPQELNGITRSLCAFRQAPLLIGSTKSNMGHPEPASGLAALTKVLLSLEHGVWAPNLHFHNPNPEIPALLDGRLQVVDRPLPVRGGNVGINSFGFGGSNVHVILQPNTRQAPAPTAHAALPHLLHASGRTLEAVQDLLEQGRQHSQDLAFVSMLNDIAATPTAAMPFRGYTVLGVEGRVQEVQQVSTNKRPLWFICSGMGTQWRGMGLSLMRLDSFRESILRSDEAVKPLGVKVSDLLLSTDERTFDDIVHAFVSLTAIQIALIDLLTSVGLKPDGIIGHSLGEVACGYADGCLSQREAVLAAYWRGQCIKDAHLPPGSMAAVGLSWEECKQRCPAGVVPACHNSEDTVTISGPQAAVNEFVEQLKQEGVFAKEVRTGGLAFHSYFMEGIAPTLLQALKKVIREPRPRSARWLSTSIPEAQWQSSLARTSSAEYNVNNLVSPVLFQEALWHIPEHAVVLEIAPHALLQAVLKRGVKSSCTIIPLMKRDHKDNLEFFLTNLGKVHLTGINVNPNALFPPVEFPAPRGTPLISPHIKWDHSQTWDVPVAEDFPNGSSSSSATVYSIDASPESPDHYLVDHCIDGRVIFPGTGYLCLVWKTLARSLGLSLEETPVVFENVSFHQATILPKTGTVALEVRLLEASHAFEVSDTGNLIVSGKVYLWEDPNSKLFDHPEVPTPPESASVSRLTQGEVYKELRLRGYDYGPQFQGICEATLEGEQGKLLWKDNWVTFMDTMLQVSILGSSQQSLQLPTRVTAIYIDPATHRQKVYRLKEDTQVADVTTSRCLGITVSGGIHISRLQTTATSRRQQEQLVPTLEKFVFTPHMEAECLSESTALQKELQLCKGLARALQTKATQQGLKAAMLGQEDPPQHGLPRLLAAACQLQLNGNLQLELGEALAQERLLLPEDPLISGLLNSQALKACVDTALENLSTLKMKVAEVLAGEGHLYSRIPALLNTQPMLQLEYTATDRHPQALKDVQTKLQQHDVAQGQWNPSDPAPSSLGALDLLVCNCALATLGDPALALDNMVAALKEGGFLLVHTVLKGHALGETLACLPSEVQPAPSLLSQEEWESLFSRKALHLVGLKRSFYGTALFLCRRAIPQEKPIFLSVEDTSFQWVDSLKSTLATSSSQPVWLTAMDCPTSGVVGLVNCLRKEPGGHRIRCILLSNLSNTSHAPKLDPGSPELQQVLKHDLVMNVYRDGAWGAFRHFQLEQDKPKEQTAHAFVNVLTRGDLASIRWVSSPLKHTQPSSSGAQLCTVYYASLNFRDIMLATGKLSPDAIPGKWASRDCMLGMEFSGRDRCGRRVMGLVPAEGLATSVLLSSDFLWDVPSSWTLEEAASVPVVYTTAYYSLVVRGRIQRGETVLIHSGSGGVGQAAISIALSLGCRVFTTVGSAEKRAYLQARFPQLDDTSFANSRDTSFEQHVLLHTGGKGVDLVLNSLAEEKLQASVRCLAQHGRFLEIGKFDLSNNHPLGMAIFLKNVTFHGILLDALFEEANDSWREVAALLKAGIRDGVVKPLKCTVFPKAQVEDAFRYMAQGKHIGKVLVQVREEEPEAVLPGAQPTLISAISKTFCPAHKSYIITGGLGGFGLELARWLVLRGAQRLVLTSRSGIRTGYQAKHIREWRRQGIQVLVSTSNVSSLEGARALIAEATKLGPVGGVFNLAMVLRDAMLENQTPELFQDVNKPKYNGTLNLDRATREACPELDYFVAFSSVSCGRGNAGQTNYGFANSTMERICEQRRHDGLPGLAVQWGAIGDVGIVLEAMGTNDTVIGGTLPQRISSCMEVLDLFLNQPHAVLSSFVLAEKKAVAHGDGDTQRDLVKAVAHILGIRDLAGINLDSTLADLGLDSLMGVEVRQILEREHDLVLPMREVRQLTLRKLQEMSSKTDSATDTTAPKSRSDTSLKQNQLNLSTLLVNPEGPTLTQLNSVQSSERPLFLVHPIEGSTTVFHSLAAKLSVPTYGLQCTQAAPLDSIPNLAAYYIDCIKQVQPEGPYRIAGYSFGACVAFEMCSQLQAQQGPAPTHNNLFLFDGSHTYVLAYTQSYRAKMTPGCEAEAEAEALCFFIKQFLDVEHSKVLEALLPLKSLEDRVAASVDLITKSHHSLDRRELSFAAVSFYHKLRAADQYKPKAKYHGNVTLLRAKTGGTYGEDLGADYNLSQVCDGKVSVHIIEGDHRTLLEGSGLESIINIIHSSLAEPRVSVREG", "length": 2504, "reference_go_mf": ["GO:0019171", "GO:0004316", "GO:0004315", "GO:0004313", "GO:0004314", "GO:0141148", "GO:0004312", "GO:0016297", "GO:0042802", "GO:0031177"], "native_canonical": true, "source": "UniProt canonical natural reference sequence"}, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_986_4v2k_assembly1_reviewed_v2", "enzyme_name": "Thiosulfate dehydrogenase", "ec": ["1.8.2.2"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "D3RVD4", "alignment_score": 462.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [30, 265], "sequence": "MRGDVRVHTASPIAAAWLLAVGLVAHAEEPPTVALTVPAAALLPDGALGESIVRGRRYLSDTPAQLPDFVGNGLACRHCHPGRDGEVGTEANAAPFVGVVGRFPQYSARHGRLITLEQRIGDCFERSLNGRALALDHPALIDMLAYMSWLSQGVPVGAVVAGHGIPTLTLEREPDGVHGEALYQARCLACHGADGSGTLDADGRYLFPPLWGPRSFNTGAGMNRQATAAGFIKHKMPLGADDSLSDEEAWDVAGFVLTHPRPLFQEPTGD", "length": 270, "reference_go_mf": ["GO:0009055", "GO:0020037", "GO:0050338"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_9e007945f0bf77488633"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_988_3shd_assembly1_reviewed_v2", "enzyme_name": "Nudix hydrolase (YmfB)", "ec": ["3.6.1.28"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "A1AA28", "alignment_score": 300.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 150], "sequence": "MFKPHVTVACVVHAEGKFLVVEETINGKALWNQPAGHLEADETLVEAAARELWEETGISAQPQHFIRMHQWIAPDKTPFLRFLFAIELEQICPTQPHDSDIDCCRWVSAEEILQASNLRSPLVAESIRCYQSGQRYPLEMIGDFNWPFTKGVI", "length": 153, "reference_go_mf": ["GO:0017110", "GO:0017111", "GO:0004787"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_2c4795db5c679fed0f16"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_990_5dqr_assembly1_reviewed_v2", "enzyme_name": "7-hydroxymethyl chlorophyll A reductase (HCAR)", "ec": ["1.17.7.2"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "Q8GS60", "alignment_score": 812.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [40, 460], "sequence": "MITVVTSRLSLLPPVFSVVNSSSSRSKDMNLEPKKKVKLREDWREKSRPIPPGGTYPAKDHCSQCGLCDTYYIAHVKEACAFLGDGMSRIESLEPVVHGRGRKADSLQDTYFGVHQEQLYARKLKPVEGAQWTGIVTTIAIEMLKSNMVEAVVCVQSDPEDRLSPRPVLARTPEEVLAARGVKPTLSPNLNTLELIEASGVKRLLFCGVGCQVQALRSVEQHLNLEKLYVLGTNCVDNGTRDGLDKFLKAASKEPETVLHYEFMQDYKVQLKHLDGHIEEVPYFSLPANDLVDVIAPSCYSCFDYTNALADLVIGYMGVPKYSGLNMTDHPQYITVRNERGKEMLSLVENLLEITPTISSGDRRPFVTETVKADDAAKFGQGPAQPAPLFVGNIIAFILNLVGPKGLEFARYSLDYHTIRNYLYVNRKWGKQRANTHMPSYAKKIVEMYNKNGQIDKMLSKK", "length": 462, "reference_go_mf": ["GO:0090415"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_d8897a5ab75ccec02fd3"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_992_4qro_assembly1_reviewed_v2", "enzyme_name": "Resorcylate decarboxylase", "ec": ["4.1.1.103"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "Q12BV1", "alignment_score": 648.0, "observed_coverage": 0.9908256880733946, "aligned_identity": 1.0, "canonical_span": [0, 324], "sequence": "MNGKIALEEHFATEETLMDSAGFVPDKDWPELRSRLLDIQDRRVRLMDEHGIETMILSLNAPAVQAIADSTRANETARRANDFLAEQVAKQPTRFRGFAALPMQDPELAARELERCVKELGFVGALVNGFSQDNRSAVPLYYDMAQYWPFWETVQALDVPFYLHPRNPLPSDARIYDGHAWLLGPTWAFGQETAVHALRLMGSGLFDKYPALKIILGHMGEGLPYSMWRIDHRNAWIKTTPKYPAKRKIVDYFNENFYLTTSGNFRTQTLIDAILEIGADRILFSTDWPFENIDHAADWFENTSISEADRKKIGWGNAQNLFKLNR", "length": 326, "reference_go_mf": ["GO:0016787", "GO:0050150"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_a449111da2c992758e36"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "reference_mapping_recovered"}
{"query_id": "mcsa_372_reviewed_v2", "enzyme_name": "NikJ, nikkomycin biosynthesis protein P1", "ec": ["5.-.-.-"], "controls": [{"chain": "a", "status": "missing_reference", "selected": null, "alternative_alignments": []}], "status": "unscoreable_or_complex_reference", "single_chain": true, "geometric_evidence": "predicted", "review_disposition": "predicted_alternative_mapped"}
{"query_id": "mcsa_501_reviewed_v2", "enzyme_name": "alcohol dehydrogenase (class V)", "ec": ["1.1.1.1"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "P28332", "alignment_score": 736.0, "observed_coverage": 1.0, "aligned_identity": 1.0, "canonical_span": [0, 368], "sequence": "MSTTGQVIRCKAAILWKPGAPFSIEEVEVAPPKAKEVRIKVVATGLCGTEMKVLGSKHLDLLYPTILGHEGAGIVESIGEGVSTVKPGDKVITLFLPQCGECTSCLNSEGNFCIQFKQSKTQLMSDGTSRFTCKGKSIYHFGNTSTFCEYTVIKEISVAKIDAVAPLEKVCLISCGFSTGFGAAINTAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIGVDVNKEKFKKAQELGATECLNPQDLKKPIQEVLFDMTDAGIDFCFEAIGNLDVLAAALASCNESYGVCVVVGVLPASVQLKISGQLFFSGRSLKGSVFGGWKSRQHIPKLVADYMAEKLNLDPLITHTLNLDKINEAVELMKTGKW", "length": 368, "reference_go_mf": ["GO:0004022", "GO:0004745", "GO:0008270"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_4a27c8a894da3867cb4c"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "predicted", "review_disposition": "predicted_alternative_mapped"}
{"query_id": "mcsa_946_reviewed_v2", "enzyme_name": "3,6-anhydro-alpha-L-galactonate cycloisomerase", "ec": ["5.5.1.25"], "controls": [{"chain": "a", "status": "assigned", "selected": {"accession": "H2IFX0", "alignment_score": 706.0, "observed_coverage": 0.9944289693593314, "aligned_identity": 1.0, "canonical_span": [0, 362], "sequence": "MKTTIKDIKTRLFKIPLKEILSDAKHGDHDHFELITTTVTLEDGSQGTGYTYTGGKGGYSIKAMLEYDIQPALIGKDATQIEEIYDFMEWHIHYVGRGGISTFAMSAVDIALWDLKGKREGLPLWKMAGGKNNTCKAYCGGIDLQFPLEKLLNNICGYLESGFNAVKIKIGRENMQEDIDRIKAVRELIGPDITFMIDANYSLTVEQAIKLSKAVEQYDITWFEEPTLPDDYKGFAEIADNTAIPLAMGENLHTIHEFGYAMDQAKLGYCQPDASNCGGITGWLKAADLITEHNIPVCTHGMQELHVSLVSAFDTGWLEVHSFPIDEYTKRPLVVENFRAVASNEPGIGVEFDWDKIAQYEV", "length": 362, "reference_go_mf": ["GO:0016836", "GO:0016853", "GO:0000287"], "native_canonical": true, "source": "UniProt canonical natural reference sequence", "sequence_id": "seq_6831c5a52b62c1a6550f"}, "alternative_alignments": []}], "status": "single_chain_control", "single_chain": true, "geometric_evidence": "experimental", "review_disposition": "experimental_alternative_mapped"}