{
  "task_id": "MED5",
  "title": "Non-inferiority trials with constancy drift and crossover correction",
  "category": "Clinical-trial biostatistics",
  "instruction_file": "instruction.md",
  "input_data": "All parameters and equations needed for the task are embedded in instruction.md.",
  "action_schema": {
    "type": "object",
    "properties": {
      "clinical_margin_m2": {
        "type": "number"
      },
      "fixed_margin_m1": {
        "type": "number"
      },
      "fixed_margin_z_statistic": {
        "type": "number"
      },
      "historical_between_trial_variance_tau2": {
        "type": "number"
      },
      "pooled_historical_effect_delta_pc": {
        "type": "number"
      },
      "pooled_historical_se_pc": {
        "type": "number"
      },
      "problem_id": {
        "type": "string",
        "const": "MED5"
      },
      "synthesis_method_one_sided_pvalue": {
        "type": "number"
      },
      "synthesis_method_z_statistic": {
        "type": "number"
      }
    },
    "required": [
      "clinical_margin_m2",
      "fixed_margin_m1",
      "fixed_margin_z_statistic",
      "historical_between_trial_variance_tau2",
      "pooled_historical_effect_delta_pc",
      "pooled_historical_se_pc",
      "problem_id",
      "synthesis_method_one_sided_pvalue",
      "synthesis_method_z_statistic"
    ],
    "additionalProperties": true,
    "description": "All numerical values must be finite JSON numbers. Exact per-field domains, units and tolerances are specified by the instruction and verifier."
  },
  "external_data_required": false
}