{
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    "L2: Specialized": 6714,
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    "L4: Field-Defining": 1568,
    "L5: Grand Challenge": 108
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  "problems_by_category": {
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    "Development, Regeneration, and Aging": 1125,
    "Disease Biology and Pathogenesis": 1125,
    "Ecology and Biodiversity": 1125,
    "Evolutionary Biology": 1125,
    "Fungal Biology": 1125,
    "Genetics, Genomics, and Epigenetics": 1125,
    "Immunology": 1125,
    "Integrative and Cross-Scale Biology": 1125,
    "Microbiology": 1125,
    "Molecular and Cell Biology": 1125,
    "Neuroscience and Behavior": 1125,
    "Parasitology": 1125,
    "Physiology and Homeostasis": 1125,
    "Plant Biology": 1125,
    "Virology": 1125
  },
  "problems_by_status": {
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    "partially_solved": 7911,
    "solved": 0
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    "openbiorq_mechanism_core": 2250,
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    "note": "Every problem record is linked to 5 distinct peer-reviewed biology publications (1 originating source + 4 domain-matched cross-referenced studies strictly within the same biological category), distinguishing genuinely open questions (OPEN-VERIFIED) from questions with primary or follow-up model-system progress (PARTIAL-PROGRESS)."
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}