This is Mitochondrial dynamics protein MID49 protein, from Mouse, contains 454 amino acids, is membrane-bound, locates in Mitochondrion.

Mitochondrial outer membrane protein which regulates mitochondrial organization, It is required for mitochondrial fission and promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins, Regulates DNM1L GTPase activity


This is Leucine aminopeptidase 1 protein, from Athlete's foot fungus, contains 373 amino acids, is soluble, locates in Extracellular.

Extracellular aminopeptidase which contributes to pathogenicity

Belongs to the peptidase M28 family, M28E subfamily


This is Leucine aminopeptidase 2 protein, from Athlete's foot fungus, contains 495 amino acids, is soluble, locates in Extracellular.

Extracellular aminopeptidase that releases a wide variety of amino acids from natural peptides and contributes to pathogenicity

Belongs to the peptidase M28 family, M28A subfamily


This is Solute carrier family 22 member 7 protein, from Rat, contains 535 amino acids, is membrane-bound, locates in Cell membrane.

Mediates sodium-independent multispecific organic anion transport, Transport of ketoprofen, indomethacin, salicylate, acetylsalicylate, prostaglandin E2, 3'-azido-3'-deoxythymidine (AZT), 2',3'-dideoxycytidine (ddC), dicarboxylates and p-aminohippurate (PAH)

Belongs to the major facilitator (TC 2,A,1) superfamily, Organic cation transporter (TC 2,A,1,19) family


This is Mesenteric estrogen-dependent adipogenesis protein protein, from Human, contains 303 amino acids, is soluble, locates in Cytoplasm.

Involved in processes that promote adipocyte differentiation, lipid accumulation, and glucose uptake in mature adipocytes


This is Methyl-CpG-binding domain-containing protein 1 protein, from Mouse-ear cress, contains 204 amino acids, has 1 CW-type Zinc finger, locates in Nucleus.

CW-type


This is Mitochondrial import inner membrane translocase subunit TIM44-2 protein, from Mouse-ear cress, contains 469 amino acids, is membrane-bound, locates in Mitochondrion.

Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner, Recruits mitochondrial HSP70 to drive protein translocation into the matrix using ATP as an energy source (By similarity)


This is Vacuole membrane protein KMS1 protein, from Mouse-ear cress, contains 416 amino acids, is membrane-bound, locates in Endoplasmic reticulum.

Involved in the early secretory pathway, Required for the correct export of secretory products from the endoplasmic reticulum (ER) and involved in the maintenance of ER integrity


This is DnaJ homolog subfamily C member 14 protein, from Rat, contains 703 amino acids, is membrane-bound, locates in Endoplasmic reticulum.

Regulates the export of target proteins, such as DRD1, from the endoplasmic reticulum to the cell surface


This is Synaptonemal complex protein 3 protein, from Golden hamster, contains 234 amino acids, locates in Nucleus.

Component of the synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase (PubMed:7876343), Required for centromere pairing during meiosis in male germ cells, Required for normal meiosis during spermatogenesis and male fertility, Plays a lesser role in female fertility, Required for efficient phosphorylation of HORMAD1 and HORMAD2


This is Actin-depolymerizing factor 7 protein, from Mouse-ear cress, contains 137 amino acids, is soluble, locates in Cytoplasm.

Actin-depolymerizing protein, Severs actin filaments (F-actin) and binds to actin monomers, Binds monomeric actin (G-actin) with a marked preference for the ADP-loaded form and inhibits the rate of nucleotide exchange on G-actin, Required for pollen tube growth, Promotes turnover of longitudinal actin cables by severing actin filaments in pollen tubes

Belongs to the actin-binding proteins ADF family


This is Phospholipase A1 protein, from Red imported fire ant, contains 346 amino acids, is soluble, locates in Extracellular.

Catalyzes the hydrolysis of phosphatidylcholine with phospholipase A1 activity (By similarity), Induces hemolytic activity (By similarity), Acts as an allergen (PubMed:3192865)

Belongs to the AB hydrolase superfamily, Lipase family


This is Transcription factor RF2a protein, from Rice, contains 380 amino acids, locates in Nucleus.

Transcription factor probably involved in vascular development and shoot tissue organization, Binds to the DNA sequence 5'-CCGAGTGTGCCCCTGG-3' present in the promoter region Box II of the phloem-specific rice tungro bacilliform virus (RTBV) promoter, May regulate tissue-specific expression of the RTBV promoter and virus replication


This is Transcription factor APG protein, from Rice, contains 505 amino acids, locates in Nucleus.

Atypical bHLH transcription factor that acts as negative regulator of grain size, Binds the transcription factor ILI6 and forms a heterodimer of antagonistic bHLH transcription factors that regulates grain length and weight by controlling cell elongation in lemma and palea, May be involved in the control of lamina inclination through brassinosteroid signaling pathway


This is Endoglycoceramidase protein, from Hydra, contains 517 amino acids, is soluble, locates in Extracellular.

Hydrolysis of the glycosidic linkage between oligosaccharides and ceramides of glycosphingolipids, optimal substrates appear to be the glycosphingolipids with a gangliotetraose structure

Belongs to the glycosyl hydrolase 5 (cellulase A) family


This is Protein LIGHT-DEPENDENT SHORT HYPOCOTYLS 1 protein, from Mouse-ear cress, contains 190 amino acids, locates in Nucleus.

Probable transcription regulator that acts as a developmental regulator by promoting cell growth in response to continuous red (cR), far-red (cFR) and blue (cB) light in a phytochrome-dependent manner, at least during seedling development

Belongs to the plant homeotic and developmental regulators ALOG protein family


This is Dapper homolog 1 protein, from Zebrafish, contains 821 amino acids, is soluble, locates in Cytoplasm.

Involved in regulation of intracellular signaling pathways during development, Specifically thought to play a role in canonical and/or non-canonical Wnt signaling pathways through interaction with DSH (Dishevelled) family proteins, Binds to dvl2 and may regulate the degradation of ctnnb1/beta-catenin, thereby modulating the transcriptional activation of target genes of the Wnt signaling pathway, Seems to activate the canonical Wnt signaling pathway


This is Juvenile hormone epoxide hydrolase protein, from Silk moth, contains 461 amino acids, is membrane-bound, locates in Endoplasmic reticulum.

Catalyzes juvenile hormone hydrolysis, Degrades juvenile hormone III (JH III) about 3 times and 5 times slower than juvenile hormone I (JH I) and II (JH II), respectively, Degrades cis-stilbene oxide and trans-stilbene oxide about 18 and 43 times slower than JH III, respectively


This is Protein LOL5 protein, from Rice, contains 163 amino acids, locates in Nucleus.

Involved in plant growth and disease resistance


This is G-protein coupled receptor family C group 6 member A protein, from Rat, contains 928 amino acids, is membrane-bound, locates in Cell membrane.

Receptor activated by amino acids with a preference for basic amino acids such as L-Lys, L-Arg and L-ornithine but also by small and polar amino acids, The L-alpha amino acids respond is augmented by divalent cations Ca(2+) and Mg(2+), Activated by extracellular calcium and osteocalcin, Seems to act through a G(q)/G(11) and G(i)-coupled pathway, Mediates the non-genomic effects of androgens in multiple tissue, May coordinate nutritional and hormonal anabolic signals through the sensing of extracellular amino acids, osteocalcin, divalent ions and its responsiveness to anabolic steroids (By similarity)

Belongs to the G-protein coupled receptor 3 family


This is Beta-1,3-glucan-binding protein protein, from Yellow mealworm beetle, contains 481 amino acids, is soluble, locates in Extracellular.

Involved in the recognition of invading microorganisms, Binds specifically to beta-1,3-glucan and activates the phenoloxidase cascade

Belongs to the insect beta-1,3-glucan binding protein family


This is TRPL translocation defect protein 14 protein, from Fruit fly, contains 475 amino acids, is soluble, locates in Cytoplasm.

GTP-binding protein which is required for the light-dependent internalization of the TRPL ion channel from the rhabdomere on the apical surface of photoreceptor cells to the cell body and for the recycling of TRPL back to the rhabdomere in the dark, Binds to 3-phosphoinositide (PtdIns(3)P) and phosphatic acid and so may interact with membranes, particularly the early endosome membrane where PtdIns(3)P is predominantly localized, Plays a role in preventing photoreceptor degeneration


This is Telomeric repeat-binding factor 2-interacting protein 1 protein, from Chicken, contains 329 amino acids, locates in Nucleus.

Acts both as a regulator of telomere function and as a transcription regulator, Involved in the regulation of telomere length and protection as a component of the shelterin complex (telosome), Does not bind DNA directly: recruited to telomeric double-stranded 5'-TTAGGG-3' repeats via its interaction with terf2, Independently of its function in telomeres, also acts as a transcription regulator: recruited to extratelomeric 5'-TTAGGG-3' sites via its association with terf2 or other factors, and regulates gene expression (By similarity)


This is Beta-carotene isomerase D27, chloroplastic protein, from Mouse-ear cress, contains 264 amino acids, locates in Plastid.

Involved in strigolactones biosynthesis by catalyzing the isomerization of the C9-C10 double bond in all-trans-beta-carotene leading to 9-cis-beta-carotene and providing the substrate for CCD7, Strigolactones are hormones that inhibit tillering and shoot branching through the MAX-dependent pathway, contribute to the regulation of shoot architectural response to phosphate-limiting conditions and function as rhizosphere signal that stimulates hyphal branching of arbuscular mycorrhizal fungi and trigger seed germination of root parasitic weeds


This is Epididymal sperm-binding protein 1 protein, from Pig, contains 223 amino acids, is soluble, locates in Extracellular.

Binds to spermatozoa upon ejaculation and may play a role in sperm capacitation, Has phosphorylcholine-binding activity

Belongs to the seminal plasma protein family


This is Histone H2B type W-T protein, from Human, contains 175 amino acids, is membrane-bound, locates in Nucleus.

Atypical histone H2B, Nucleosomes containing it are structurally and dynamically indistinguishable from those containing conventional H2B, However, unlike conventional H2B, does not recruit chromosome condensation factors and does not participate in the assembly of mitotic chromosomes, May be important for telomere function


This is Developmental pluripotency-associated protein 2 protein, from Human, contains 298 amino acids, locates in Nucleus.

Binds to target gene promoters, including NKX2-5 and SYCE1, but not GATA4, and may be involved in the maintenance of the active epigenetic status of these genes


This is Protein DBF4 homolog A protein, from African clawed frog, contains 661 amino acids, has 1 DBF4-type Zinc finger, locates in Nucleus.

Regulatory subunit for cdc7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation, Not required during the initiation of DNA replication in egg and during early embryonic development but is required later and throughout development, The complex cdc7-dbf4a phosphorylates mcm2 subunit


This is Serine protease 33 protein, from Mouse, contains 277 amino acids, is soluble, locates in Extracellular.

Serine protease that has amidolytic activity, cleaving its substrates before Arg residues


This is Vang-like protein 1 protein, from Mouse, contains 526 amino acids, is membrane-bound, locates in Cell membrane.


This is Coiled-coil domain-containing protein 50 protein, from Mouse, contains 305 amino acids, is soluble, locates in Cytoplasm.


This is GDP-fucose transporter 1 protein, from Mouse-ear cress, contains 341 amino acids, is membrane-bound, locates in Golgi apparatus.

Acts as the major nucleotide-sugar transporter for the import of GDP-Fucose into the Golgi lumen, Transports GDP-Fucose in a strict counter-exchange mode, Is required for proper plant growth and development (PubMed:27381418), Acts also as a GDP-mannose transporter that may be involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen (PubMed:15480787)

Belongs to the nucleotide-sugar transporter family, GDP-Mannose:GMP antiporter (GMA) (TC 2,A,7,13) subfamily


This is bZIP transcription factor 68 protein, from Mouse-ear cress, contains 389 amino acids, locates in Nucleus.

Transcriptional activator that binds to the G-box motif (5'-CACGTG-3') and other cis-acting elements with 5'-ACGT-3' core, such as Hex, C-box and as-1 motifs, Possesses high binding affinity to G-box, much lower affinity to Hex and C-box, and little affinity to as-1 element (PubMed:18315949), G-box and G-box-like motifs are cis-acting elements defined in promoters of certain plant genes which are regulated by such diverse stimuli as light-induction or hormone control (Probable), Binds to the G-box motif 5'-CACGTG-3' of LHCB2,4 (At3g27690) promoter, May act as transcriptional activator in light-regulated expression of LHCB2,4, Probably binds DNA as monomer, DNA-binding activity is redox-dependent (PubMed:22718771)


This is CRS2-associated factor 2, chloroplastic protein, from Maize, contains 611 amino acids, is soluble, locates in Plastid.

Required for the splicing of group IIB introns in chloroplasts, Forms splicing particles with CRS2, Interacts with RNA and confers intron specificity of the splicing particles


This is Probable acyl-activating enzyme 18, peroxisomal protein, from Mouse-ear cress, contains 727 amino acids, locates in Peroxisome.

May be involved in the peroxisomal activation of 2,4-dichlorophenoxybutyric acid (2,4-DB), a precursor of active auxins that inhibit root growth

Belongs to the ATP-dependent AMP-binding enzyme family


This is Protein WVD2-like 3 protein, from Mouse-ear cress, contains 338 amino acids, is soluble, locates in Cytoplasm.

Microtubule-associated protein (MAP) that regulates the orientation of interphase cortical microtubules, Binds to, bundles and stabilizes microtubules, Required for the organization and stability of cortical microtubules in hypocotyls, Required for normal hypocotyl cell elongation, Acts as negative regulator of hypocotyl cell elongation in the light


This is Protein WAVE-DAMPENED 2 protein, from Mouse-ear cress, contains 202 amino acids, is soluble, locates in Cytoplasm.

Microtubule-associated protein (MAP) that regulates the orientation of interphase cortical microtubules, Able to bundle microtubules in vitro, Modulates both rotational polarity and anisotropic cell expansion during organ growth, Promotes clockwise root and etiolated hypocotyls coiling, clockwise leaf curling, but left-handed petiole twisting


This is Cardioacceleratory peptide receptor protein, from Fruit fly, contains 495 amino acids, is membrane-bound, locates in Cell membrane.

Binds to the cardioactive peptide (CCAP), which is a neuropeptide

Belongs to the G-protein coupled receptor 1 family, Vasopressin/oxytocin receptor subfamily


This is Defensin protein, from American dog tick, contains 74 amino acids, is soluble, locates in Extracellular.

Antibacterial activity against Gram-positive and Gram-negative bacteria

Belongs to the invertebrate defensin family, Type 2 subfamily


This is Protein argonaute protein, from Giardia lamblia, contains 781 amino acids, is soluble, locates in Cytoplasm.

Plays an essential role in growth and, with Dicer, also involved in microRNA (miRNA)-mediated translational repression, The RNA interference pathway is implicated in antigenic variation having a role in regulation of variant-specific surface protein (VSP)-coding gene expression, Several VSP genes are transcribed but only transcripts encoding the VSP to be expressed accumulate, Antisense RNAs corresponding to the silenced VSP genes are detected

Belongs to the argonaute family, Ago subfamily


This is COMM domain-containing protein 2 protein, from Human, contains 199 amino acids, is soluble, locates in Cytoplasm.

May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237), May down-regulate activation of NF-kappa-B (PubMed:15799966)


This is Beta-fibrinogenase stejnefibrase-2 protein, from Chinese green tree viper, contains 258 amino acids, is soluble, locates in Extracellular.

Snake venom serine protease that degrades preferentially beta-chain of fibrinogen (FGB)

Belongs to the peptidase S1 family, Snake venom subfamily


This is Alpha- and beta-fibrinogenase stejnefibrase-1 protein, from Chinese green tree viper, contains 258 amino acids, is soluble, locates in Extracellular.

Snake venom serine protease, Degrades concomitantly alpha- (FGA) and beta-chains of fibrinogen (FGB)


This is Nucleolar protein 12 protein, from Mouse, contains 217 amino acids, locates in Nucleus.

May bind to 28S rRNA, In vitro binds single-stranded nucleic acids


This is Protein CREG2 protein, from Mouse, contains 288 amino acids, is soluble, locates in Extracellular.


This is 2-aminomuconic semialdehyde dehydrogenase protein, from Mouse, contains 487 amino acids, is soluble, locates in Cytoplasm.

Catalyzes the NAD-dependent oxidation of 2-aminomuconic semialdehyde of the kynurenine metabolic pathway in L-tryptophan degradation

Belongs to the aldehyde dehydrogenase family


This is POC1 centriolar protein homolog B protein, from Mouse, contains 476 amino acids, is soluble, locates in Cytoplasm.

Plays an important role in centriole assembly and/or stability and ciliogenesis, Involved in early steps of centriole duplication, as well as in the later steps of centriole length control, Acts in concert with POC1A to ensure centriole integrity and proper mitotic spindle formation, Required for primary cilia formation, ciliary length and also cell proliferation, Required for retinal integrity


This is Zinc finger CCCH domain-containing protein 14 protein, from Mouse, contains 735 amino acids, has 5 C3H1-type Zinc finger, locates in Nucleus.

Involved in poly(A) tail length control in neuronal cells, Binds the polyadenosine RNA oligonucleotides


This is Zinc transporter 6 protein, from Mouse, contains 460 amino acids, is membrane-bound, locates in Golgi apparatus.

Has probably no intrinsic transporter activity but together with SLC30A5 forms a functional zinc ion:proton antiporter heterodimer, mediating zinc entry into the lumen of organelles along the secretory pathway (Probable), As part of that zinc ion:proton antiporter, contributes to zinc ion homeostasis within the early secretory pathway and regulates the activation and folding of enzymes like alkaline phosphatases and enzymes involved in phosphatidylinositol glycan anchor biosynthesis (By similarity)

Belongs to the cation diffusion facilitator (CDF) transporter (TC 2,A,4) family, SLC30A subfamily


This is Serine protease inhibitor Kazal-type 6 protein, from Mouse, contains 105 amino acids, is soluble, locates in Extracellular.

Serine protease inhibitor selective for kallikreins, Efficiently inhibits KLK5 and human KLK2, KLK4, KLK5, KLK6, KLK7, KLK12, KLK13 and KLK14, Doesn't inhibit human KLK1 and KLK8


This is Protein Wfdc21 protein, from Mouse, contains 63 amino acids, is soluble, locates in Extracellular.

May promote activation of the metalloproteinase MMP2


This is Developmental pluripotency-associated protein 4 protein, from Mouse, contains 296 amino acids, locates in Nucleus.

May be involved in the maintenance of active epigenetic status of target genes, May inhibit differentiation of embryonic stem (ES) cells into a primitive ectoderm lineage


This is MAM domain-containing protein 2 protein, from Mouse, contains 686 amino acids, is soluble, locates in Extracellular.


This is Protein TIFY 11a protein, from Rice, contains 179 amino acids, locates in Nucleus.

Repressor of jasmonate (JA) responses, Forms a ternary complex with RSS3 and BHLH94 to negatively regulate JA-responsive genes (PubMed:23715469), Acts as positive regulator of tolerance to salt stress (PubMed:19618278, PubMed:25617318), Involved in salt tolerance by modulating potassium homeostasis through JA signaling and regulation of the expression of potassium ion transporter genes, Acts as a transcriptional regulator targeted by the SCF(COI1) E3 ubiquitin ligase complexes in the JA signaling pathway, and interacts with BHLH062 that may directly regulate the ion transporter genes (PubMed:25617318), Acts as positive regulator of tolerance to dehydration stress (PubMed:19618278), Acts as negative regulator of tolerance to cold stress by interacting with MYB30 (PubMed:28062835)


This is Protein G1 protein, from Rice, contains 276 amino acids, locates in Nucleus.

Probable transcription regulator that acts as a developmental regulator by promoting cell growth in response to light (By similarity), Transcription regulator that restrains empty glumes growth, lemmas of the sterile florets located at the lateral side of the rice spikelet, to maintain their small size, probably by repressing lemma identity via transcription regulation


This is Protein WVD2-like 1 protein, from Mouse-ear cress, contains 286 amino acids, is soluble, locates in Cytoplasm.

Microtubule-associated protein (MAP) that regulates the orientation of interphase cortical microtubules, Modulates both rotational polarity and anisotropic cell expansion during organ growth, Promotes clockwise root and etiolated hypocotyls coiling, clockwise leaf curling, but left-handed petiole twisting


This is Acanthoscurrin-1 protein, from Tarantula spider, contains 156 amino acids, is soluble, locates in Extracellular.

Antimicrobial protein, Strong activity against the Gram-negative bacterium E,coli SBS363 and yeast C,albicans, No detectable activity against the Gram-positive bacterium M,luteus


This is Protein Turandot C protein, from Fruit fly, contains 129 amino acids, is soluble, locates in Extracellular.

A humoral factor that may play a role in stress tolerance


This is Putative C-type lectin-like domain family 1 protein, from Human, contains 167 amino acids, is membrane-bound, locates in Cell membrane.

May function in mediating immune cell-cell interactions, May act as a T-cell costimulatory molecule, enhancing anti-CD3-induced proliferation, May play a role in the interaction of dendritic cells with T-cells and the cells of the adaptive immune response


This is Protein FAM9C protein, from Human, contains 166 amino acids, locates in Nucleus.


This is Reticulon-1 protein, from Mouse, contains 780 amino acids, is membrane-bound, locates in Endoplasmic reticulum.

Inhibits amyloid precursor protein processing, probably by blocking BACE1 activity


This is Leucine-rich repeat-containing protein 10 protein, from Mouse, contains 274 amino acids, locates in Nucleus.

May play important roles in cardiac development and/or cardiac function


This is BPI fold-containing family A member 1 protein, from Rat, contains 270 amino acids, is soluble, locates in Extracellular.

Lipid-binding protein which shows high specificity for the surfactant phospholipid dipalmitoylphosphatidylcholine (DPPC), Plays a role in the innate immune responses of the upper airways, Reduces the surface tension in secretions from airway epithelia and inhibits the formation of biofilm by pathogenic Gram-negative bacteria, such as P,aeruginosa and K,pneumoniae, Negatively regulates proteolytic cleavage of SCNN1G, an event that is required for activation of the epithelial sodium channel (ENaC), and thereby contributes to airway surface liquid homeostasis and proper clearance of mucus, Plays a role in the airway inflammatory response after exposure to irritants, May attract macrophages and neutrophils

Belongs to the BPI/LBP/Plunc superfamily, Plunc family


This is Isoamylase 2, chloroplastic protein, from Mouse-ear cress, contains 882 amino acids, locates in Plastid.

Involved in the trimming of pre-amylopectin chains, Accelerates the crystallization of nascent amylopectin molecules during starch synthesis, ISA1 and ISA2 work exclusively together as a multimeric holoenzyme, ISA1-ISA2 removes preferentially branches that are very close to other branches

Belongs to the glycosyl hydrolase 13 family


This is Thioredoxin-like 2-2, chloroplastic protein, from Mouse-ear cress, contains 236 amino acids, locates in Plastid.

Thiol-disulfide oxidoreductase that may participate in various redox reactions, Possesses insulin disulfide bonds reducing activity


This is Actin-depolymerizing factor 12 protein, from Mouse-ear cress, contains 137 amino acids, is soluble, locates in Cytoplasm.

Actin-depolymerizing protein, Severs actin filaments (F-actin) and binds to actin monomers

Belongs to the actin-binding proteins ADF family


This is Protein ABA DEFICIENT 4, chloroplastic protein, from Mouse-ear cress, contains 220 amino acids, is membrane-bound, locates in Plastid.

Required for neoxanthin biosynthesis, an intermediary step in abscisic acid (ABA) biosynthesis, Probably not involved directly in the enzymatic conversion of violaxanthin to neoxanthin, Cannot convert violaxanthin to neoxanthin in vitro, Required for ABA biosynthesis in response to drought stress (PubMed:17470058), Required for neoxanthin biosynthesis which is involved in photoprotection of photosystem II (PSII), Neoxanthin acts as an antioxidant within the photosystem PSII supercomplex (PubMed:17351115)


This is Isocitrate dehydrogenase [NAD] catalytic subunit 6, mitochondrial protein, from Mouse-ear cress, contains 374 amino acids, locates in Mitochondrion.

Catalytic subunit of the NAD(+)-dependent isocitrate dehydrogenase involved in the oxidative decarboxylation of isocitrate to 2-oxoglutarate (Probable), Performs an essential role in the oxidative function of the citric acid cycle

Belongs to the isocitrate and isopropylmalate dehydrogenases family


This is Centromere protein L protein, from Human, contains 344 amino acids, locates in Nucleus.

Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation, May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex


This is Adipogenin protein, from Mouse, contains 80 amino acids, is membrane-bound, locates in Nucleus.

Plays a role in stimulating adipocyte differentiation and development


This is UDP-xylose transporter 3 protein, from Mouse-ear cress, contains 357 amino acids, is membrane-bound, locates in Golgi apparatus.

Nucleotide-sugar transporter that transports UDP-xylose and UMP in a strict counter-exchange mode

Belongs to the TPT transporter family, TPT (TC 2,A,7,9) subfamily


This is Inactive ribonuclease-like protein 10 protein, from Pig, contains 213 amino acids, is soluble, locates in Extracellular.

Secreted proximal epididymal protein required for post-testicular sperm maturation and male fertility, May be involved in sperm adhesion to the egg zona pellucida (By similarity), Does not have ribonuclease activity

Belongs to the pancreatic ribonuclease family


This is Diapause-specific peptide protein, from Leaf beetle, contains 65 amino acids, is soluble, locates in Extracellular.

Has antifungal activity against T,rubrum, Blocks voltage-dependent N-type calcium channels (Cav2,2 / CACNA1B)


This is Solute carrier family 35 member G2 protein, from Human, contains 412 amino acids, is membrane-bound, locates in Cell membrane.

Belongs to the SLC35G solute transporter family


This is Olfactory receptor 51E1 protein, from Human, contains 317 amino acids, is membrane-bound, locates in Cell membrane.

Belongs to the G-protein coupled receptor 1 family


This is Mitochondrial import inner membrane translocase subunit TIM50 protein, from Mouse-ear cress, contains 376 amino acids, is membrane-bound, locates in Mitochondrion.

Essential component of the TIM17:23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane


This is Enoyl-CoA hydratase 2, peroxisomal protein, from Mouse-ear cress, contains 309 amino acids, locates in Peroxisome.

Bidirectional monofunctional enoyl-CoA hydratase 2 involved in the degradation of even cis-unsaturated fatty acids, Devoid of 3-hydroxyacyl-CoA dehydrogenase activity


This is ATP-dependent 6-phosphofructokinase 5, chloroplastic protein, from Mouse-ear cress, contains 537 amino acids, locates in Plastid.

Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis

Belongs to the phosphofructokinase type A (PFKA) family, PPi-dependent PFK group II subfamily, Atypical ATP-dependent clade 'X' sub-subfamily


This is Probable glucan endo-1,3-beta-glucosidase At4g16260 protein, from Mouse-ear cress, contains 344 amino acids, is soluble, locates in Extracellular.

May be involved in plant defense against cyst nematode pathogens

Belongs to the glycosyl hydrolase 17 family


This is SWR1-complex protein 4 protein, from Mouse-ear cress, contains 441 amino acids, locates in Nucleus.

Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling, Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A


This is Countin-2 protein, from Social amoeba, contains 254 amino acids, is soluble, locates in Extracellular.

Cell-counting factor that limits the minimum size of the multicellular structure, May up-regulate the expression of both gp24 and gp80, which mediate cell adhesion


This is Small ribosomal subunit protein uS15m protein, from Fruit fly, contains 280 amino acids, locates in Mitochondrion.

Essential for gut mitochondrial activity, Might be involved in tissue specific growth factor production

Belongs to the universal ribosomal protein uS15 family


This is GPI ethanolamine phosphate transferase 1 protein, from Fission yeast, contains 935 amino acids, is membrane-bound, locates in Endoplasmic reticulum.

Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis, Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor

Belongs to the PIGG/PIGN/PIGO family, PIGN subfamily


This is Arabinogalactan endo-beta-1,4-galactanase A protein, from Aspergillus niger, contains 350 amino acids, is soluble, locates in Extracellular.

Endogalactanase involved in the degradation of plant cell wall polysaccharides, and more particularly of hairy regions of pectin

Belongs to the glycosyl hydrolase 53 family


This is Corticotropin-releasing factor receptor 1 protein, from Chicken, contains 420 amino acids, is membrane-bound, locates in Cell membrane.

G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin), Has high affinity for CRH and UCN, Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase, Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels

Belongs to the G-protein coupled receptor 2 family


This is PYLa/PGLa B protein, from African clawed frog, contains 64 amino acids, is soluble, locates in Extracellular.

PGLa and PGLa-H display a broad-spectrum of antibacterial activity against a range of Gram-positive and Gram-negative bacteria, PGLa also displays antifungal activity against C,albicans ATCC 14053, PGLa-H shows moderate antibacterial activity against the multidrug-resistant methicillin-resistant S,aureus (MRSA) but exhibits very little hemolytic activity

Belongs to the gastrin/cholecystokinin family, Magainin subfamily


This is Serine protease 41 protein, from Mouse, contains 322 amino acids, is membrane-bound, locates in Cell membrane.


This is Protein MTO1 homolog, mitochondrial protein, from Mouse, contains 669 amino acids, locates in Mitochondrion.

Involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs


This is Protein boule-like protein, from Mouse, contains 293 amino acids, is soluble, locates in Cytoplasm.

Probable RNA-binding protein, which may be required during spermatogenesis, May act by binding to the 3'-UTR of mRNAs and regulating their translation (By similarity)


This is Phospholipase A(1) LCAT3 protein, from Mouse-ear cress, contains 447 amino acids, is membrane-bound, locates in Endoplasmic reticulum.

Hydrolyzes the sn-1 acylester bond of phospholipids, Phosphatidylcholine, phosphatidylethanolamine and phosphatidic acid can be used as substrates, Weak activity with lysophosphatidylcholine and no activity with tripalmitoylglycerol and cholesteryl oleate, Seems to have a preference for unsaturated fatty acids at the sn-1 position

Belongs to the AB hydrolase superfamily, Lipase family


This is Respiratory burst oxidase homolog protein A protein, from Potato, contains 963 amino acids, is membrane-bound, locates in Cell membrane.

Calcium-dependent NADPH oxidase that generates superoxide, Involved in the rapid and transient phase I oxidative burst induced by pathogen infection


This is Protein KAKU4 protein, from Mouse-ear cress, contains 485 amino acids, is membrane-bound, locates in Nucleus.

Required for nucleus structure organization (e,g, size and shape)


This is WPP domain-interacting protein 3 protein, from Mouse-ear cress, contains 459 amino acids, is membrane-bound, locates in Nucleus.

Mediates and enhances the nuclear envelope docking of RANGAP proteins mediated by WIT1 and WIT2 in the undifferentiated cells of root tips (PubMed:17600715), As component of the SUN-WIP-WIT2-KAKU1 complex, mediates the transfer of cytoplasmic forces to the nuclear envelope (NE), leading to nuclear shape changes (PubMed:25759303)


This is Phosphatase IMPL1, chloroplastic protein, from Mouse-ear cress, contains 371 amino acids, is soluble, locates in Plastid.

Phosphatase acting preferentially on D-myoinositol 1-phosphate (D-Ins 1-P)

Belongs to the inositol monophosphatase superfamily


This is LIM domain-containing protein WLIM1 protein, from Mouse-ear cress, contains 190 amino acids, is soluble, locates in Cytoplasm.

Binds to actin filaments and promotes cross-linking into thick bundles, Has an actin-stabilizing activity, The actin regulatory activities are not regulated by pH and [Ca(2+)]


This is Serine--tRNA synthetase-like protein Slimp protein, from Fruit fly, contains 464 amino acids, locates in Mitochondrion.

Essential protein which may play a role in mitochondrial morphogenesis and function, Has transfer RNA (tRNA)-binding activity and can bind tRNA(Ser) but does not have serine--tRNA ligase activity and does not bind ATP

Belongs to the class-II aminoacyl-tRNA synthetase family, Type-1 seryl-tRNA synthetase subfamily


This is Epididymal sperm-binding protein 1 protein, from Human, contains 223 amino acids, is soluble, locates in Extracellular.

Binds to spermatozoa upon ejaculation and may play a role in sperm capacitation, Has phosphorylcholine-binding activity (By similarity)

Belongs to the seminal plasma protein family


This is DAZ-associated protein 1 protein, from African clawed frog, contains 360 amino acids, is soluble, locates in Cytoplasm.

RNA-binding protein, which is required during gametogenesis, May be involved in the actin-dependent anchoring of Vg1 mRNA in the vegetal cortex of the oocyte


This is PYLa/PGLa A protein, from African clawed frog, contains 64 amino acids, is soluble, locates in Extracellular.


This is Protein HPH1 protein, from Baker's yeast, contains 602 amino acids, is membrane-bound, locates in Endoplasmic reticulum.

Calcineurin-dependent protein required for growth under high NaCl, alkaline pH and cell wall stress


This is G-protein coupled receptor 20 protein, from Human, contains 358 amino acids, is membrane-bound, locates in Cell membrane.

Orphan receptor with constitutive G(i) signaling activity that activate cyclic AMP


This is S-type anion channel SLAH2 protein, from Mouse-ear cress, contains 519 amino acids, is membrane-bound, locates in Cell membrane.

Slow, weak voltage-dependent S-type anion efflux channel involved in maintenance of anion homeostasis

Belongs to the SLAC1 S-type anion channel family


This is Nicolin-1 protein, from Human, contains 213 amino acids, locates in Nucleus.


This is Hemogen protein, from Human, contains 484 amino acids, locates in Nucleus.

Regulates the proliferation and differentiation of hematopoietic cells, Overexpression block the TPA-induced megakaryocytic differentiation in the K562 cell model, May also prevent cell apoptosis through the activation of the nuclear factor-kappa B (NF-kB)


This is Large ribosomal subunit protein bL20m protein, from Human, contains 149 amino acids, locates in Mitochondrion.

Belongs to the bacterial ribosomal protein bL20 family


This is Large ribosomal subunit protein uL13m protein, from Human, contains 178 amino acids, locates in Mitochondrion.

Belongs to the universal ribosomal protein uL13 family


This is Ent-kaurenoic acid oxidase 2 protein, from Mouse-ear cress, contains 489 amino acids, is membrane-bound, locates in Endoplasmic reticulum.

Catalyzes three successive oxidations of ent-kaurenoic acid giving gibberellin 12 (GA12), a key step in gibberellins (GAs) biosynthesis, GAs, which are involved many processes, including stem elongation, play a central role in plant development


This is Fatty-acid-binding protein 3, chloroplastic protein, from Mouse-ear cress, contains 287 amino acids, is soluble, locates in Plastid.

Fatty-acid-binding protein, Interacts with most fatty acids tested and has maximal relative affinity for C16:0

Belongs to the chalcone isomerase family


This is NAC domain-containing protein 19 protein, from Mouse-ear cress, contains 317 amino acids, locates in Nucleus.

Transcription factors that bind specifically to the 5'-CATGTG-3' motif


This is Cleavage and polyadenylation specificity factor subunit 3-I protein, from Mouse-ear cress, contains 693 amino acids, locates in Nucleus.

Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition, May function as mRNA 3'-end-processing endonuclease and also be involved in the histone 3'-end pre-mRNA processing

Belongs to the metallo-beta-lactamase superfamily, RNA-metabolizing metallo-beta-lactamase-like family, INTS11 subfamily


This is Protein PLASTID MOVEMENT IMPAIRED 2 protein, from Mouse-ear cress, contains 607 amino acids, is soluble, locates in Cytoplasm.

Required for the chloroplast avoidance response under high intensity blue light, This avoidance response consists in the relocation of chloroplasts on the anticlinal side of exposed cells, Acts in association with WEB1 to maintain the velocity of chloroplast photorelocation movement via cp-actin filaments regulation


This is Leucine-rich repeat-containing protein 17 protein, from Mouse, contains 443 amino acids, is soluble, locates in Extracellular.

Involved in bone homeostasis, Acts as a negative regulator of RANKL-induced osteoclast precursor differentiation from bone marrow precursors


This is Alpha-hemoglobin-stabilizing protein protein, from Mouse, contains 102 amino acids, is soluble, locates in Cytoplasm.

Acts as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development, Specifically protects free alpha-hemoglobin from precipitation


This is Mitochondrial pyruvate carrier 2 protein, from Mouse, contains 127 amino acids, is membrane-bound, locates in Mitochondrion.

Mediates the uptake of pyruvate into mitochondria

Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2,A,105) family


This is Proline-rich AKT1 substrate 1 protein, from Mouse, contains 257 amino acids, is soluble, locates in Cytoplasm.

Subunit of mTORC1, which regulates cell growth and survival in response to nutrient and hormonal signals, mTORC1 is activated in response to growth factors or amino acids, Growth factor-stimulated mTORC1 activation involves a AKT1-mediated phosphorylation of TSC1-TSC2, which leads to the activation of the RHEB GTPase that potently activates the protein kinase activity of mTORC1, Amino acid-signaling to mTORC1 requires its relocalization to the lysosomes mediated by the Ragulator complex and the Rag GTPases, Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis, mTORC1 phosphorylates EIF4EBP1 and releases it from inhibiting the elongation initiation factor 4E (eiF4E), mTORC1 phosphorylates and activates S6K1 at 'Thr-389', which then promotes protein synthesis by phosphorylating PDCD4 and targeting it for degradation, Within mTORC1, AKT1S1 negatively regulates mTOR activity in a manner that is dependent on its phosphorylation state and binding to 14-3-3, Inhibits RHEB-GTP-dependent mTORC1 activation, Substrate for AKT1 phosphorylation, but can also be activated by AKT1-independent mechanisms, May also play a role in nerve growth factor-mediated neuroprotection


This is Synaptonemal complex central element protein 1 protein, from Mouse, contains 329 amino acids, locates in Nucleus.

Major component of the transverse central element of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase (PubMed:15944401), Requires SYCP1 in order to be incorporated into the central element (PubMed:15944401, PubMed:16968740), May have a role in the synaptonemal complex assembly, stabilization and recombination (PubMed:15944401)


This is MAPK-interacting and spindle-stabilizing protein protein, from Mouse, contains 263 amino acids, is soluble, locates in Cytoplasm.

Involved in the maintenance of the spindle integrity during the cytostatic factor (CSF) arrest of oocytes


This is CST complex subunit TEN1 protein, from Mouse, contains 161 amino acids, locates in Nucleus.

Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex, The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves, Initially the CST complex has been proposed to protect telomeres from DNA degradation (PubMed:19854130), However, the CST complex has been shown to be involved in several aspects of telomere replication, The CST complex inhibits telomerase and is involved in telomere length homeostasis; it is proposed to bind to newly telomerase-synthesized 3' overhangs and to terminate telomerase action implicating the association with the ACD:POT1 complex thus interfering with its telomerase stimulation activity, The CST complex is also proposed to be involved in fill-in synthesis of the telomeric C-strand probably implicating recruitment and activation of DNA polymerase alpha, The CST complex facilitates recovery from many forms of exogenous DNA damage; seems to be involved in the re-initiation of DNA replication at repaired forks and/or dormant origins (By similarity)


This is Nucleotide exchange factor SIL1 protein, from Mouse, contains 465 amino acids, is soluble, locates in Endoplasmic reticulum.

Required for protein translocation and folding in the endoplasmic reticulum (ER), Functions as a nucleotide exchange factor for the ER lumenal chaperone HSPA5


This is Zinc finger protein 22 protein, from Rat, contains 237 amino acids, has 5 C2H2-type Zinc finger, locates in Nucleus.

Binds DNA through the consensus sequence 5'-CAATG-3', May be involved in transcriptional regulation and may play a role in tooth formation (By similarity)

Belongs to the krueppel C2H2-type zinc-finger protein family


This is Proteasome assembly chaperone 2 protein, from Mouse, contains 264 amino acids, locates in Nucleus.

Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1, The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization (By similarity)


This is 1,4-dihydroxy-2-naphthoyl-CoA thioesterase 2 protein, from Mouse-ear cress, contains 157 amino acids, locates in Peroxisome.

Catalyzes the hydrolysis of the thioester bond of 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA) in peroxisomes, a necessary step to form the naphthoquinone ring of phylloquinone (vitamin K(1)), Displayed also slight thioesterase activity towards benzoyl-CoA, Is not active on phenylacetyl-CoA, succinyl-CoA and palmitoyl-CoA thioesters

Belongs to the 4-hydroxybenzoyl-CoA thioesterase family, DHNA-CoA hydrolase subfamily


This is Mitochondrial outer membrane protein porin 2 protein, from Mouse-ear cress, contains 276 amino acids, is membrane-bound, locates in Mitochondrion.

Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules, The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV, The open state has a weak anion selectivity whereas the closed state is cation-selective (By similarity), Involved in plant growth and development at the vegetative and reproductive stages, Is important for leaf and pollen development and mitochondrial membrane potential steady state, May be involved in ABA-mediated early seedling development and disease resistance

Belongs to the eukaryotic mitochondrial porin (TC 1,B,8,1) family


This is Cyclin-dependent kinase inhibitor 3 protein, from Mouse-ear cress, contains 222 amino acids, is soluble, locates in Nucleus.

Binds and inhibits CYCD2-1/CDKA-1 complex kinase activity, May target specifically CDKA-1

Belongs to the CDI family, ICK/KRP subfamily


This is Mitochondrial outer membrane protein porin 4 protein, from Mouse-ear cress, contains 274 amino acids, is membrane-bound, locates in Mitochondrion.

Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules, The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV, The open state has a weak anion selectivity whereas the closed state is cation-selective (By similarity), Involved in plant growth and development at the vegetative and reproductive stages, Is important for leaf and pollen development and mitochondrial membrane potential steady state, May be involved in disease resistance


This is Probable serine/threonine-protein kinase PBL16 protein, from Mouse-ear cress, contains 408 amino acids, is membrane-bound, locates in Cell membrane.

May be involved in plant defense signaling

Belongs to the protein kinase superfamily, Ser/Thr protein kinase family


This is Mitochondrial import receptor subunit TOM9-2 protein, from Mouse-ear cress, contains 99 amino acids, is membrane-bound, locates in Mitochondrion.

Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins, Together with TOM20 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the translocation pore (By similarity)


This is Arogenate dehydratase 5, chloroplastic protein, from Mouse-ear cress, contains 425 amino acids, is soluble, locates in Plastid.

Converts the prephenate produced from the shikimate-chorismate pathway into phenylalanine


This is NADH dehydrogenase [ubiquinone] iron-sulfur protein 8-B, mitochondrial protein, from Mouse-ear cress, contains 222 amino acids, locates in Mitochondrion.

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis, Complex I functions in the transfer of electrons from NADH to the respiratory chain, The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity), May donate electrons to ubiquinone

Belongs to the complex I 23 kDa subunit family


This is Conotoxin tx9a protein, from Cloth-of-gold cone, contains 88 amino acids, is soluble, locates in Extracellular.

Neurotoxin, In vivo, intracranial injection into mice of 10 pmol/g of the peptide induces running in circles and hyperactivity, At higher doses (50 pmol/g), the mice exhibit running and climbing symptoms for close to one hour, Between 130 and 150 pmol/g, characteristic 'spasmodic' symptomatology is elicited, A hand clap would make mice jump high and start running rapidly, When exposed to a loud hand clap, or if the cage cover were dropped, the mice lose motor control and exhibit seizure-like symptoms from which they eventually recover, At the highest doses tested (over 250 pmol/g), after the characteristic spasmodic symptomatology, lethality occurs, Injection of a similar dose range intramuscularly into Siamese fighting fish elicited no unusual symptomatology


This is Dynein regulatory complex subunit 3 protein, from Human, contains 523 amino acids, is soluble, locates in Cytoplasm.

Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes


This is Coiled-coil domain-containing protein 113 protein, from Human, contains 377 amino acids, is soluble, locates in Cytoplasm.

Component of centriolar satellites contributing to primary cilium formation


This is Ribosome production factor 1 protein, from Human, contains 349 amino acids, locates in Nucleus.


This is Popeye domain-containing protein 2 protein, from Human, contains 364 amino acids, is membrane-bound, locates in Cell membrane.

Important for the maintenance of cardiac function, Plays a regulatory function in heart rate dynamics mediated, at least in part, through cAMP-binding and, probably, by increasing cell surface expression of the potassium channel KCNK2 and enhancing current density


This is Acyl-coenzyme A diphosphatase fit1 protein, from Fission yeast, contains 250 amino acids, is membrane-bound, locates in Endoplasmic reticulum.

Fatty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatty acyl-CoA to yield acyl-4'-phosphopantetheine and adenosine 3',5'-bisphosphate (By similarity), Preferentially hydrolyzes unsaturated long-chain acyl-CoA substrates in the endoplasmic reticulum (ER) lumen (By similarity), This catalytic activity is required for maintaining ER structure and for lipid droplets (LDs) biogenesis, which are lipid storage organelles involved in maintaining lipid and energy homeostasis (By similarity), May directly bind to diacylglycerol (DAGs) and triacylglycerol, which is also important for LD biogenesis (By similarity), May support directional budding of nacent LDs from the ER into the cytosol by reducing DAG levels at sites of LD formation (By similarity), May play a role in the regulation of cell morphology and cytoskeletal organization (By similarity)

Belongs to the FIT family, Fungal FIT2B/SCS3 subfamily


This is Carboxypeptidase N catalytic chain protein, from Mouse, contains 457 amino acids, is soluble, locates in Extracellular.

Protects the body from potent vasoactive and inflammatory peptides containing C-terminal Arg or Lys (such as kinins or anaphylatoxins) which are released into the circulation


This is Testicular haploid expressed gene protein protein, from Mouse, contains 375 amino acids, locates in Nucleus.

May be involved (but not essential) in spermatogenesis


This is L-type lectin-domain containing receptor kinase VIII.1 protein, from Mouse-ear cress, contains 715 amino acids, is membrane-bound, locates in Cell membrane.

In the N-terminal section; belongs to the leguminous lectin family


This is Lectin-like protein LEC protein, from Mouse-ear cress, contains 271 amino acids, is soluble, locates in Extracellular.

Plays a role in defense responses triggered by jasmonate, ethylene and chitin


This is UBP1-associated protein 2C protein, from Mouse-ear cress, contains 404 amino acids, locates in Nucleus.

Heterogeneous nuclear ribonucleoprotein (hnRNP)-like protein that acts as component of a complex regulating the turnover of mRNAs in the nucleus, Binds with high affinity to RNA molecules that contain U-rich sequences in 3'-UTRs, May function in complex with UBP1 and contribute to the stabilization of mRNAs in the nucleus (By similarity)


This is Retinoblastoma-related protein 1 protein, from Maize, contains 867 amino acids, locates in Nucleus.

Regulator of biological processes that recruits a histone deacetylase to control gene transcription, May play a role in the entry into mitosis, negatively regulating the cell proliferation, Formation of stable complexes with geminiviridae replication-associated proteins may create a cellular environment which favors viral DNA replication

Belongs to the retinoblastoma protein (RB) family


This is Peptidyl-prolyl cis-trans isomerase FKBP18, chloroplastic protein, from Mouse-ear cress, contains 232 amino acids, locates in Plastid.

PPIases accelerate the folding of proteins, It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity)


This is Arogenate dehydrogenase 2, chloroplastic protein, from Mouse-ear cress, contains 358 amino acids, locates in Plastid.

Involved in the biosynthesis of tyrosine, Has a weak prephenate dehydrogenase activity

Belongs to the prephenate/arogenate dehydrogenase family


This is Protein PLANT CADMIUM RESISTANCE 2 protein, from Mouse-ear cress, contains 152 amino acids, is membrane-bound, locates in Cell membrane.

Zinc transporter acting in both zinc extrusion and long-distance zinc transport, Involved in the loading of zinc into the xyleme and in the detoxification of excess zinc at the epidermal cells, Acts independently from the zinc transporters HMA2 and HMA4, May be also involved in cadmium resistance


This is Cyclin-dependent kinase inhibitor 5 protein, from Mouse-ear cress, contains 189 amino acids, is soluble, locates in Nucleus.

Inhibits CYCD2-1/CDKA-1 complex kinase activity without interaction with the complex


This is Photosynthetic NDH subunit of subcomplex B 3, chloroplastic protein, from Mouse-ear cress, contains 204 amino acids, is membrane-bound, locates in Plastid.

NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain, The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone, Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient


This is Protein LIGHT-DEPENDENT SHORT HYPOCOTYLS 4 protein, from Mouse-ear cress, contains 195 amino acids, locates in Nucleus.

Probable transcription regulator that acts as a developmental regulator by promoting cell growth in response to light (By similarity), May suppress organ differentiation in the boundary region

Belongs to the plant homeotic and developmental regulators ALOG protein family


This is Transcription factor MYB48 protein, from Mouse-ear cress, contains 256 amino acids, locates in Nucleus.


This is Mechanosensitive ion channel protein 10 protein, from Mouse-ear cress, contains 734 amino acids, is membrane-bound, locates in Cell membrane.

Mechanosensitive channel that opens in response to stretch forces in the membrane lipid bilayer


This is Peptidyl-prolyl cis-trans isomerase FKBP19, chloroplastic protein, from Mouse-ear cress, contains 256 amino acids, locates in Plastid.


This is LIM domain-containing protein WLIM2b protein, from Mouse-ear cress, contains 199 amino acids, is soluble, locates in Cytoplasm.

Binds to actin filaments and promotes cross-linking into thick bundles, Has an actin-stabilizing activity, The actin regulatory activities are not regulated by pH and [Ca(2+)]


This is Isoamylase 3, chloroplastic protein, from Mouse-ear cress, contains 764 amino acids, locates in Plastid.

Involved in starch catabolism, ISA3 removes different branches than ISA1-ISA2, namely short chains that prevent amylopectin crystallization, May be the debranching enzyme required to assist beta-amylases for starch degradation in leaves at night

Belongs to the glycosyl hydrolase 13 family


This is Squamosa promoter-binding-like protein 15 protein, from Mouse-ear cress, contains 354 amino acids, has 1 SBP-type Zinc finger, locates in Nucleus.

SBP-type

Trans-acting factor that binds specifically to the consensus nucleotide sequence 5'-TNCGTACAA-3'


This is Probable F-box protein At3g61730 protein, from Mouse-ear cress, contains 359 amino acids, locates in Nucleus.

Regulates tapetum degeneration and pollen maturation during anther development


This is Neoxanthin synthase, chloroplastic protein, from Potato, contains 498 amino acids, locates in Plastid.

Involved in the synthesis of neoxanthin, the last product of carotenoid synthesis and a precursor of abscisic acid


This is Isochorismate synthase 2, chloroplastic protein, from Mouse-ear cress, contains 562 amino acids, locates in Plastid.

Isochorismate synthase involved in the synthesis of salicylic acid (SA) required for both local and systemic acquired resistance (LAR and SAR) while SA synthesized through the phenylalanine ammonium lyase (PAL) pathway seems to potentiate plant cell death, Also involved in phylloquinone (vitamin K1) synthesis, Has no isochorismate pyruvate lyase (IPL) activity

Belongs to the isochorismate synthase family


This is Olfactomedin-like protein 3 protein, from Human, contains 406 amino acids, is soluble, locates in Extracellular.

Secreted scaffold protein that plays an essential role in dorsoventral patterning during early development, Stabilizes axial formation by restricting chordin (CHRD) activity on the dorsal side, Acts by facilitating the association between the tolloid proteases and their substrate chordin (CHRD), leading to enhance chordin (CHRD) degradation (By similarity), May have matrix-related function involved in placental and embryonic development, or play a similar role in other physiological processes


This is Cytokine-like protein 1 protein, from Human, contains 136 amino acids, is soluble, locates in Extracellular.


This is Integrator complex subunit 10 protein, from Human, contains 710 amino acids, locates in Nucleus.

Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing, The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable), May be not involved in the recruitment of cytoplasmic dynein to the nuclear envelope by different components of the INT complex (PubMed:23904267)

Belongs to the Integrator subunit 10 family


This is Large ribosomal subunit protein mL66 protein, from Human, contains 196 amino acids, locates in Mitochondrion.

Belongs to the bacterial ribosomal protein bS18 family, Mitochondrion-specific ribosomal protein mL66 subfamily


This is Large ribosomal subunit protein uL16m protein, from Human, contains 251 amino acids, locates in Mitochondrion.

Belongs to the universal ribosomal protein uL16 family


This is Small ribosomal subunit protein uS2B protein, from Fission yeast, contains 287 amino acids, is soluble, locates in Cytoplasm.

Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell, The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules, The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain, The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel (By similarity), uS2 is required for the assembly and/or stability of the 40S ribosomal subunit, Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits (PubMed:14623272)

Belongs to the universal ribosomal protein uS2 family


This is Xrcc4-like factor 1 protein, from Fission yeast, contains 203 amino acids, locates in Nucleus.

Involved in non-homologous end joining (NHEJ) in the repair of double-strand DNA breaks (DSB), Has a role in meiosis

Belongs to the XRCC4-XLF family, XLF subfamily


This is Gamma-tubulin complex component gfh1 protein, from Fission yeast, contains 577 amino acids, is soluble, locates in Cytoplasm.

Required for proper anchoring of astral microtubules at the spindle pole bodies (SPBs), during anaphase, ensuring correct cell polarity


This is Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial protein, from Fission yeast, contains 159 amino acids, is membrane-bound, locates in Mitochondrion.

Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q)


This is Lipase 5 protein, from Yeast, contains 463 amino acids, is soluble, locates in Extracellular.

Belongs to the AB hydrolase superfamily, Lipase family


This is Homeobox protein otx5-B protein, from African clawed frog, contains 290 amino acids, locates in Nucleus.

Transcription factor involved in anterior and eye development, Promotes the differentiation of both rod and cone photoreceptors cells in the retina, Together with other retinal homeobox proteins, acts as an effector of a cellular clock which, depending on cell cycle progression, establishes the generation of distinct retinal neuronal cell types, Acts synergistically with nrl to activate the rhodopsin promoter, Promotes the formation of anterior regions and represses the formation of posterior structures during development


This is GPI ethanolamine phosphate transferase 1 protein, from Mouse, contains 931 amino acids, is membrane-bound, locates in Endoplasmic reticulum.

Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis, Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor, May act as suppressor of replication stress and chromosome missegregation

Belongs to the PIGG/PIGN/PIGO family, PIGN subfamily


This is Protein rough sheath 2 protein, from Maize, contains 370 amino acids, locates in Nucleus.

Transcription factor required for normal cell differentiation, Interacts directly with asymmetric leaves 2 (AS2) to repress the knox homeobox genes


This is Auxin-responsive protein SAUR41 protein, from Mouse-ear cress, contains 147 amino acids, is soluble, locates in Cytoplasm.

Plays a role in the regulation of cell expansion, root meristem patterning and auxin transport


This is Scarecrow-like protein 7 protein, from Mouse-ear cress, contains 542 amino acids, locates in Nucleus.

Probable transcription factor involved in plant development (Probable), Involved in environmental abiotic stress resistance, May increase the expression of stress-responsive genes (By similarity), Binds DNA in vitro (By similarity)


This is Arogenate dehydratase/prephenate dehydratase 6, chloroplastic protein, from Mouse-ear cress, contains 413 amino acids, is soluble, locates in Plastid.

Converts the prephenate produced from the shikimate-chorismate pathway into phenylalanine (PubMed:17726025), Dehydratase that uses arogenate and prephenate as substrates (PubMed:17726025), Utilzes more efficiently arogenate than prephenate (PubMed:17726025)


This is Peroxisomal and mitochondrial division factor 2 protein, from Mouse-ear cress, contains 323 amino acids, is membrane-bound, locates in Mitochondrion.

Involved in morphogenesis and proliferation of mitochondria, Does not act redundantly with PMD1, Is not involved in peroxisomal proliferation


This is Phospholipase A1-IIdelta protein, from Mouse-ear cress, contains 412 amino acids, is soluble, locates in Cytoplasm.

Acylhydrolase that catalyzes the hydrolysis of phosphatidylcholine (PC) at the sn-1 position, High activity toward PC, medium activity toward monogalactosyldiacylglycerol (MGDG) and low activity toward triacylglycerol (TAG), Confers sensitivity to UV-B radiation probably by deesterifying membrane phospholipids


This is Folate-biopterin transporter 1, chloroplastic protein, from Mouse-ear cress, contains 560 amino acids, is membrane-bound, locates in Plastid.

Mediates folate monoglutamate transport involved in tetrahydrofolate biosynthesis, It also mediates transport of antifolates, such as methotrexate and aminopterin

Belongs to the major facilitator superfamily, Folate-biopterin transporter (TC 2,A,71) family


This is Ankyrin repeat domain-containing protein EMB506, chloroplastic protein, from Mouse-ear cress, contains 315 amino acids, locates in Plastid.

Involved in the initial differentiation of the proplastid during the embryo development, Also required for correct cotyledon, true leaf and cauline leaf margin development


This is Small ribosomal subunit protein uS5c protein, from Spinach, contains 308 amino acids, locates in Plastid.

Component of the chloroplast ribosome (chloro-ribosome), a dedicated translation machinery responsible for the synthesis of chloroplast genome-encoded proteins, including proteins of the transcription and translation machinery and components of the photosynthetic apparatus

Belongs to the universal ribosomal protein uS5 family


This is Acyl-CoA-binding domain-containing protein 3 protein, from Mouse-ear cress, contains 362 amino acids, is soluble, locates in Extracellular.

Binds medium- and long-chain acyl-CoA esters with very high affinity, Can interact in vitro with arachidonyl-CoA, barely with oleoyl-CoA, but not with palmitoyl-CoA


This is Trehalase protein, from Mouse-ear cress, contains 626 amino acids, is membrane-bound, locates in Cell membrane.

Involved in the regulation of trehalose content by hydrolyzing trehalose to glucose

Belongs to the glycosyl hydrolase 37 family


This is Probable acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, mitochondrial protein, from Mouse-ear cress, contains 336 amino acids, locates in Mitochondrion.

Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that in bacteria anchors the lipopolysaccharide to the outer membrane of the cell, Lipid A-like molecules in plants may serve as structural components of the outer membranes of mitochondria and/or chloroplasts, or may be involved in signal transduction or plant defense responses (Potential)

Belongs to the transferase hexapeptide repeat family, LpxA subfamily


This is 1,4-dihydroxy-2-naphthoyl-CoA thioesterase 1 protein, from Mouse-ear cress, contains 156 amino acids, locates in Peroxisome.

Catalyzes the hydrolysis of the thioester bond of 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA) in peroxisomes, a necessary step to form the naphthoquinone ring of phylloquinone (vitamin K(1)), Is not active on benzoyl-CoA, phenylacetyl-CoA, succinyl-CoA and palmitoyl-CoA thioesters

Belongs to the 4-hydroxybenzoyl-CoA thioesterase family, DHNA-CoA hydrolase subfamily


This is Complement component C7 protein, from Pig, contains 843 amino acids, is soluble, locates in Extracellular.

Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells, C7 serves as a membrane anchor

Belongs to the complement C6/C7/C8/C9 family


This is Venom peptide isomerase heavy chain protein, from North American funnel-web spider, contains 243 amino acids, is soluble, locates in Extracellular.

Peptide isomerase that inverts the chirality at the Ser-81 of omega-Aga IVB, Acts cofactor-independently


This is Probable ribosome biogenesis protein RLP24 protein, from Human, contains 163 amino acids, locates in Nucleus.

Involved in the biogenesis of the 60S ribosomal subunit, Ensures the docking of GTPBP4/NOG1 to pre-60S particles (By similarity)

Belongs to the eukaryotic ribosomal protein eL24 family


This is Uncharacterized RNA-binding protein C902.04 protein, from Fission yeast, contains 589 amino acids, locates in Nucleus.


This is Chromatin-remodeling complexes subunit ngg1 protein, from Fission yeast, contains 551 amino acids, locates in Nucleus.

Transcription regulator, Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA, SLIK and ADA, SAGA is involved in RNA polymerase II-dependent transcriptional regulation of a subset of genes, At the promoters, SAGA is required for recruitment of the basal transcription machinery, It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination, SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac), SAGA interacts with DNA via upstream activating sequences (UASs), SALSA, an altered form of SAGA, may be involved in positive transcriptional regulation, SLIK is proposed to have partly overlapping functions with SAGA, It preferentially acetylates methylated histone H3, ADA preferentially acetylates nucleosomal histones H3 (at 'Lys-14' and 'Lys-18') and H2B


This is Pseudouridine-metabolizing bifunctional protein C1861.05 protein, from Fission yeast, contains 747 amino acids, is soluble, locates in Cytoplasm.

Bifunctional enzyme that catalyzes the phosphorylation of pseudouridine to pseudouridine 5'-phosphate (PsiMP), and the reversible cleavage of pseudouridine 5'-phosphate to ribose 5-phosphate and uracil, Is involved in a pseudouridine degradation pathway

In the C-terminal section; belongs to the carbohydrate kinase PfkB family


This is Gamma-tubulin complex subunit mod21 protein, from Fission yeast, contains 677 amino acids, is soluble, locates in Cytoplasm.

Component of the gamma-tubulin complex that is required for the regulation of both interphase microtubule organization and nucleation, and mitotic bipolar spindles, Required for correct septation


This is Protein pal1 protein, from Fission yeast, contains 425 amino acids, is membrane-bound, locates in Cell membrane.

Involved in cellular morphogenesis and cell wall integrity, Important for the maintenance of a cylindrical cell shape


This is Protein Turandot B protein, from Fruit fly, contains 138 amino acids, is soluble, locates in Extracellular.

A humoral factor that may play a role in stress tolerance


This is Large ribosomal subunit protein mL55 protein, from Fruit fly, contains 107 amino acids, locates in Mitochondrion.

Involved in mitochondrial biogenesis and G2/M phase cell cycle progression

Belongs to the mitochondrion-specific ribosomal protein mL55 family


This is Testis-specific zinc finger protein topi protein, from Fruit fly, contains 814 amino acids, has 10 C2H2-type Zinc finger, locates in Nucleus.

Required for male meiotic division and spermatid differentiation, Required for accumulation of aly and comr on chromatin, May function as a transcription factor


This is Protein dpy-30 homolog protein, from Fruit fly, contains 134 amino acids, locates in Nucleus.

Component of the SET1 complex that specifically di- and trimethylates 'Lys-4' of histone H3 and of the MLL3/4 complex which also methylates histone H3 'Lys-4', Inhibits MTF-1 transcription factor activity


This is Tubulin glycylase 3A protein, from Fruit fly, contains 992 amino acids, is soluble, locates in Cytoplasm.

Polylycylase which modifies alpha- and beta-tubulin, generating side chains of glycine on the gamma-carboxyl groups of specific glutamate residues within the C-terminal tail of alpha- and beta-tubulin, Involved both in the side-chain initiation and elongation steps of the polyglycylation reaction by adding a single glycine chain to generate monoglycine side chains and by elongating monoglycine side chains to polyglycine side chains


This is Zinc finger CCCH domain-containing protein 3 protein, from Fruit fly, contains 597 amino acids, has 3 C3H1-type Zinc finger, locates in Nucleus.

Required for the export of polyadenylated mRNAs from the nucleu; binds to polyadenylated mRNA, and is involved in the regulation of mRNA polyadenylation


This is Chloride channel protein ClC-Kb protein, from African clawed frog, contains 689 amino acids, is membrane-bound, locates in Cell membrane.

Voltage-gated chloride channel, Chloride channels have several functions including the regulation of cell volume, the stabilization of membrane potential, signal transduction and transepithelial transport

Belongs to the chloride channel (TC 2,A,49) family


This is Methyl-CpG-binding domain-containing protein 10 protein, from Mouse-ear cress, contains 384 amino acids, locates in Nucleus.

Probable transcriptional regulator (By similarity), Required for nucleolar dominance that consist in the silencing of rRNA genes inherited from one progenitor in genetic hybrids


This is Regulator of hypoxia-inducible factor 1 protein, from Caenorhabditis elegans, contains 502 amino acids, is membrane-bound, locates in Endoplasmic reticulum.

Involved in the response to variation in environmental oxygen levels by inhibiting hif-1-mediated gene transcription in a vhl-1-independent manner (PubMed:16980385), Plays a role in susceptibility to killing mediated by P,aeruginosa and by pore-forming toxins produced by B,thuringiensis (PubMed:20011506, PubMed:20865124), Probably by preventing hif-1 transcriptional activity, regulates behavioral responses, such as locomotion speed following acute reoxygenation (PubMed:22405203), Plays a role in normal egg-laying probably by regulating spermatogenesis and in body morphogenesis (PubMed:16980385)


This is Mitochondrial import inner membrane translocase subunit Tim10B protein, from Caenorhabditis elegans, contains 111 amino acids, is membrane-bound, locates in Mitochondrion.

Component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane, The TIM22 complex forms a twin-pore translocase that uses the membrane potential as the external driving force, In the TIM22 complex, it may act as a docking point for the soluble 70 kDa complex that guides the target proteins in transit through the aqueous mitochondrial intermembrane space (By similarity)


This is Inactive cytidine monophosphate-N-acetylneuraminic acid hydroxylase protein, from Human, contains 501 amino acids, is soluble, locates in Cytoplasm.

Sialic acids are components of carbohydrate chains of glycoconjugates and are involved in cell-cell recognition and cell-pathogen interactions, That protein has no CMP-N-acetylneuraminate monooxygenase activity and is not able to convert CMP-N-acetylneuraminic acid (CMP-Neu5Ac) into its hydroxylated derivative CMP-N-glycolylneuraminic acid (CMP-Neu5Gc), a sialic acid abundantly expressed at the surface of many cells in vertebrates (PubMed:9624188), However, it may play a role in Wnt signaling (PubMed:19890979)

Belongs to the CMP-Neu5Ac hydroxylase family


This is Venom plasminogen activator Haly-PA protein, from Korean slamosa snake, contains 258 amino acids, is soluble, locates in Extracellular.

Snake venom serine protease that activates plasminogen, Displays indirect fibrino(geno)lytic activity through conversion of plasminogen to plasmin, Shows a preferential cleavage at Arg-|-Xaa instead of Lys-|-Xaa bonds

Belongs to the peptidase S1 family, Snake venom subfamily


This is Cytochrome B5 isoform C protein, from Mouse-ear cress, contains 132 amino acids, is membrane-bound, locates in Endoplasmic reticulum.

Membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases, including fatty acid desaturases


This is Protein TIC 20-IV, chloroplastic protein, from Mouse-ear cress, contains 284 amino acids, is membrane-bound, locates in Plastid.

Involved in protein precursor import into chloroplasts, Partially redundant with TIC20-I, but not with TIC20-II or TIC20-V


This is UPF0603 protein At1g54780, chloroplastic protein, from Mouse-ear cress, contains 285 amino acids, is membrane-bound, locates in Plastid.


This is Cytochrome B5 isoform D protein, from Mouse-ear cress, contains 140 amino acids, is membrane-bound, locates in Endoplasmic reticulum.


This is Protein shisa-1 protein, from African clawed frog, contains 269 amino acids, is membrane-bound, locates in Endoplasmic reticulum.

Required for head formation during gastrulation, Functions as an inhibitor for the caudalizing signals wnt and fgf, does not inhibit bmp, activin and nodal signaling in head formation process, Induces retention of fzd8 in the endoplasmic reticulum and inhibits trafficking of fzd8 to the cell surface


This is Metallocarboxypeptidase A protein, from Athlete's foot fungus, contains 422 amino acids, is soluble, locates in Extracellular.

Extracellular metalloprotease that contributes to pathogenicity


This is ATP-dependent 6-phosphofructokinase subunit gamma protein, from Yeast, contains 351 amino acids, is soluble, locates in Cytoplasm.

Structural subunit of pyrophosphate--fructose 6-phosphate 1-phosphotransferase, Not required for catalytic activity, Fine-tunes allosteric regulation of the ATP-PFK by ATP, fructose 2,6-bisphosphate and AMP


This is Brevinin-1PLb protein, from Pickerel frog, contains 70 amino acids, is soluble, locates in Extracellular.

Antimicrobial activity against the Gram-negative bacterium E,coli, the Gram-positive bacterium S,aureus and the yeast C,albicans

Belongs to the frog skin active peptide (FSAP) family, Brevinin subfamily


This is Brevinin-1PLc protein, from Pickerel frog, contains 70 amino acids, is soluble, locates in Extracellular.


This is Temporin-1PLa protein, from Pickerel frog, contains 62 amino acids, is soluble, locates in Extracellular.

Antimicrobial activity against the Gram-positive bacterium S,aureus

Belongs to the frog skin active peptide (FSAP) family, Temporin subfamily


This is Pleurain-A2 protein, from Yunnan pond frog, contains 69 amino acids, is soluble, locates in Extracellular.

Antimicrobial peptide, Has activity against the Gram-positive bacterium S,aureus ATCC2592 (MIC=15 ug/ml), the Gram-negative bacteria E,coli ATCC25922 (MIC=60 ug/ml), B,dysenteriae (MIC=60 ug/ml), H,pylori NTCT11637 (MIC=30 ug/ml), and the fungus C,albicans ATCC2002 (MIC=30 ug/ml), Has little hemolytic activity on rabbit red blood cells

Belongs to the frog skin active peptide (FSAP) family, Pleurain subfamily


This is Mu-theraphotoxin-An1a protein, from Tarantula spider, contains 47 amino acids, is soluble, locates in Extracellular.

Is toxic to insects, Reduces amplitude and frequency of spontaneous firing and inhibits voltage-gated sodium current (Nav) in the dorsal unpaired median (DUM) neurons of P,americana

Belongs to the neurotoxin 12 (Hwtx-2) family, 01 (Ap1a) subfamily


This is Toxin CSTX-17 protein, from American wandering spider, contains 40 amino acids, is soluble, locates in Extracellular.

Belongs to the neurotoxin 02 (plectoxin) family


This is Toxin CSTX-18 protein, from American wandering spider, contains 51 amino acids, is soluble, locates in Extracellular.

Belongs to the neurotoxin 02 (plectoxin) family, 07 subfamily


This is Dybowskin-1CDYa protein, from Dybovsky's frog, contains 59 amino acids, is soluble, locates in Extracellular.

Antimicrobial peptide, Has activity against the Gram-positive bacterium S,aureus (MIC=6 uM) and the Gram-negative bacterium E,coli (MIC=3 uM), Lacks hemolytic activity against human erythrocytes


This is Protein kintoun protein, from Chlamydomonas smithii, contains 675 amino acids, is soluble, locates in Cytoplasm.

Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella, Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment

Belongs to the PIH1 family, Kintoun subfamily


This is Mutanase Pc12g07500 protein, from Penicillium chrysogenum, contains 445 amino acids, is soluble, locates in Extracellular.

Hydrolyzes 1,3-alpha-glucan predominantly into pentasaccharides, May enhance the efficacy of fungal antibiotics by degrading bacterial exopolysaccharides

Belongs to the glycosyl hydrolase 71 family


This is Calcium sensing receptor, chloroplastic protein, from Maize, contains 395 amino acids, is membrane-bound, locates in Plastid.

Modulates cytoplasmic Ca(2+) concentration and is crucial for proper stomatal regulation in response to elevated levels of external Ca(2+), May function by regulating concentrations of inositol 1,4,5-trisphosphate (IP3), which in turn triggers release of Ca(2+) from internal stores, May play a role in de-etiolation


This is Potassium channel toxin alpha-KTx 8.7 protein, from Lesser Asian scorpion, contains 57 amino acids, is soluble, locates in Extracellular.

Inhibits voltage-gated potassium channel rKv1,1/KCNA1 at nanomolar ranges (IC(50)=8,5 nM)

Belongs to the short scorpion toxin superfamily, Potassium channel inhibitor family, Alpha-KTx 08 subfamily


This is Ocellatin-PT1 protein, from Ceara white-lipped frog, contains 66 amino acids, is soluble, locates in Extracellular.

Has antibacterial activity against Gram-negative bacterium E,coli ATCC 25922 (MIC=300 uM) but not against S,pneumoniae ATCC 700603, S,choleraesuis ATCC 14028 or Gram-positive bacterium S,aureus ATCC 29313, Shows virtually no hemolytic activity and no cytotoxicity

Belongs to the frog skin active peptide (FSAP) family, Ocellatin subfamily


This is Ocellatin-PT2 protein, from Ceara white-lipped frog, contains 66 amino acids, is soluble, locates in Extracellular.

Has no antibacterial activity against Gram-negative bacteria E,coli ATCC 25922, S,pneumoniae ATCC 700603 and S,choleraesuis ATCC 14028 or against Gram-positive bacterium S,aureus ATCC 29313, Shows no hemolytic activity and no cytotoxicity


This is Ocellatin-PT3 protein, from Ceara white-lipped frog, contains 66 amino acids, is soluble, locates in Extracellular.

Has antibacterial activity against Gram-negative bacterium E,coli ATCC 25922 (MIC=320 uM) but not against S,pneumoniae ATCC 700603, S,choleraesuis ATCC 14028 or Gram-positive bacterium S,aureus ATCC 29313, Shows no hemolytic activity and no cytotoxicity


This is Ocellatin-PT4 protein, from Ceara white-lipped frog, contains 66 amino acids, is soluble, locates in Extracellular.

Has antibacterial activity against Gram-negative bacteria E,coli ATCC 25922 (MIC=80 uM), K,pneumoniae ATCC 700603 (MIC=310 uM) and S,choleraesuis ATCC 14028 (MIC=310 uM), Shows no hemolytic activity and no cytotoxicity


This is Ocellatin-PT5 protein, from Ceara white-lipped frog, contains 66 amino acids, is soluble, locates in Extracellular.

Has antibacterial activity against Gram-negative bacterium E,coli ATCC 25922 (MIC=300 uM) but not against S,pneumoniae ATCC 700603, S,choleraesuis ATCC 14028 or Gram-positive bacterium S,aureus ATCC 29313, Shows very little hemolytic activity and no cytotoxicity


This is Ocellatin-PT6 protein, from Ceara white-lipped frog, contains 73 amino acids, is soluble, locates in Extracellular.

Has antibacterial activity against Gram-negative bacterium E,coli ATCC 25922 (MIC=120 uM) but not against S,pneumoniae ATCC 700603, S,choleraesuis ATCC 14028 or against Gram-positive bacterium S,aureus ATCC 29313, Shows no hemolytic activity and no cytotoxicity


This is Ocellatin-PT7 protein, from Ceara white-lipped frog, contains 73 amino acids, is soluble, locates in Extracellular.

Has antibacterial activity against Gram-negative bacteria E,coli ATCC 25922 (MIC=60 uM) and S,choleraesuis ATCC 14028 (MIC=240 uM) and against Gram-positive bacterium S,aureus ATCC 29313 (MIC=240 uM), Shows no hemolytic activity and no cytotoxicity


This is Ocellatin-PT8 protein, from Ceara white-lipped frog, contains 73 amino acids, is soluble, locates in Extracellular.

Has antibacterial activity against Gram-negative bacteria E,coli ATCC 25922 (MIC=60 uM), K,pneumoniae ATCC 700603 (MIC=240 uM) and S,choleraesuis ATCC 14028 (MIC=240 uM) and against Gram-positive bacterium S,aureus ATCC 29313 (MIC=240 uM), Shows no hemolytic activity and no cytotoxicity


This is OcyC3 protein, from South American scorpion, contains 75 amino acids, is soluble, locates in Extracellular.

Amphipathic peptide with probable antimicrobial activity

Belongs to the non-disulfide-bridged peptide (NDBP) superfamily, Medium-length antimicrobial peptide (group 3) family


This is Conotoxin Cal5a L1 protein, from California cone, contains 76 amino acids, is soluble, locates in Extracellular.

Probable neurotoxin with unknown target, Possibly targets ion channels


This is Extracellular metalloprotease ARB_05317 protein, from Trichophyton mentagrophytes, contains 271 amino acids, is soluble, locates in Extracellular.

Secreted metalloproteinase that allows assimilation of proteinaceous substrates, Plays a pivotal role as a pathogenicity determinant during infections and contributes to the ability of the pathogen to persist within the mammalian host (By similarity)


This is Probable metallocarboxypeptidase A protein, from Trichophyton mentagrophytes, contains 422 amino acids, is soluble, locates in Extracellular.

Extracellular metalloprotease that contributes to pathogenicity


This is Uncharacterized FAD-linked oxidoreductase ARB_02478 protein, from Trichophyton mentagrophytes, contains 588 amino acids, is soluble, locates in Extracellular.

Belongs to the oxygen-dependent FAD-linked oxidoreductase family


This is Exo-beta-D-glucosaminidase ARB_07888 protein, from Trichophyton mentagrophytes, contains 882 amino acids, is soluble, locates in Extracellular.

Hydrolyzes chitosan and chitooligosaccharides with retention of anomeric configuration (By similarity)

Belongs to the glycosyl hydrolase 2 family


This is Probable leucine aminopeptidase 2 protein, from Trichophyton mentagrophytes, contains 495 amino acids, is soluble, locates in Extracellular.

Extracellular aminopeptidase that releases a wide variety of amino acids from natural peptides and contributes to pathogenicity

Belongs to the peptidase M28 family, M28A subfamily


This is Probable leucine aminopeptidase 1 protein, from Trichophyton mentagrophytes, contains 373 amino acids, is soluble, locates in Extracellular.

Extracellular aminopeptidase which contributes to pathogenicity

Belongs to the peptidase M28 family, M28E subfamily


This is High osmolarity signaling protein SHO1A protein, from Hortaea werneckii, contains 321 amino acids, is membrane-bound, locates in Cell membrane.

Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity


This is High osmolarity signaling protein SHO1B protein, from Hortaea werneckii, contains 320 amino acids, is membrane-bound, locates in Cell membrane.


This is TLC domain-containing protein 1 protein, from Chicken, contains 252 amino acids, is membrane-bound, locates in Cell membrane.

Regulates the composition and fluidity of the plasma membrane (By similarity), Inhibits the incorporation of membrane-fluidizing phospholipids containing omega-3 long-chain polyunsaturated fatty acids (LCPUFA) and thereby promotes membrane rigidity (By similarity), Does not appear to have any effect on LCPUFA synthesis (By similarity)


This is Calcium-binding protein SP84 protein, from Green rice leafhopper, contains 687 amino acids, is soluble, locates in Extracellular.

Binds calcium, During feeding of the phloem sap, protein is injected into sieve tubes of rice plants, This process may suppress the sieve-element clogging and facilitate continuous ingestion from sieve tubes


This is Putative amine oxidase [copper-containing] protein, from Freshwater pearl mussel, contains 781 amino acids, is soluble, locates in Extracellular.

Belongs to the copper/topaquinone oxidase family


This is Laccase-2 protein, from Filobasidiella neoformans var. grubii, contains 594 amino acids, is soluble, locates in Extracellular.

Laccase that catalyzes the oxidation of certain aromatic compounds, including L-dopa, to quinones, which then polymerize to melanin (By similarity), Able to oxidize a wide variety of aromatic diphenol and diamino groups in the ortho, meta, and para positions but not monophenolic groups such as in phenol, tyramine, or tyrosine (By similarity), Plays an important role in virulence (By similarity), Plays a role in dissemination to extrapulmonary sites but is not involved in pulmonary growth or in elicitation of cellular immune responses in the lung (By similarity)

Belongs to the multicopper oxidase family


This is Laccase-1 protein, from Filobasidiella neoformans var. grubii, contains 624 amino acids, is soluble, locates in Extracellular.


This is Jingdongin-1 protein, from Chinese torrent frog, contains 63 amino acids, is soluble, locates in Extracellular.

The synthetic peptide has antimicrobial activity against Gram-negative bacterium B,dysenteriae (MIC=35 ug/ml), against Gram-positive bacteria S,aureus ATCC 2592 (MIC=4,7 ug/ml) and B,subtilis ATCC 6633 (MIC=9,38 ug/ml) and against fungus C,albicans (MIC=18,75 ug/ml), Has no activity against Gram-negative bacterium E,coli ATCC 25922 but exhibits low hemolytic activity at concentrations up to 200 ug/ml

Belongs to the frog skin active peptide (FSAP) family, Brevinin subfamily


This is 2-hydroxy-palmitic acid dioxygenase mpo1 protein, from Fission yeast, contains 222 amino acids, is membrane-bound, locates in Endoplasmic reticulum.

Dioxygenase that catalyzes the alpha-oxidation of 2-hydroxy fatty acids in an iron-dependent manner (By similarity), Involved in metabolism of phytosphingosine and is required for proper endoplasmic reticulum stress response (By similarity)


This is Small ribosomal subunit protein uS7m protein, from Fission yeast, contains 259 amino acids, locates in Mitochondrion.

Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain, The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane

Belongs to the universal ribosomal protein uS7 family


This is Ubiquitin-like-specific protease 2 protein, from Fission yeast, contains 638 amino acids, locates in Nucleus.


This is Uncharacterized carboxypeptidase C24C9.08 protein, from Fission yeast, contains 596 amino acids, is membrane-bound, locates in Lysosome/Vacuole.


This is RNA polymerase I-specific transcription initiation factor rrn5 protein, from Fission yeast, contains 556 amino acids, locates in Nucleus.

Component of the UAF (upstream activation factor) complex which interacts with the upstream element of the RNA polymerase I promoter and forms a stable preinitiation complex, UAF seems to stimulate basal transcription to a fully activated level


This is Probable NADH-ubiquinone oxidoreductase C3A11.07, mitochondrial protein, from Fission yeast, contains 551 amino acids, locates in Mitochondrion.

Belongs to the NADH dehydrogenase family


This is Probable isocitrate dehydrogenase [NADP], mitochondrial protein, from Fission yeast, contains 439 amino acids, locates in Mitochondrion.

Belongs to the isocitrate and isopropylmalate dehydrogenases family


This is Ribosomal RNA-processing protein 14-N protein, from Fission yeast, contains 154 amino acids, locates in Nucleus.

Involved in ribosome biogenesis and cell polarity, Required for the synthesis of both 40S and 60S ribosomal subunits and may also play some direct role in correct positioning of the mitotic spindle during mitosis (By similarity)


This is Meiotically up-regulated gene 80 protein protein, from Fission yeast, contains 461 amino acids, locates in Nucleus.


This is GYF domain-containing protein mpd2 protein, from Fission yeast, contains 992 amino acids, is soluble, locates in Cytoplasm.

Has a role in mRNA export from the nucleus


This is HMG box-containing protein C10F6.08c protein, from Fission yeast, contains 341 amino acids, locates in Nucleus.


This is Large ribosomal subunit protein eL19B protein, from Fission yeast, contains 193 amino acids, is soluble, locates in Cytoplasm.

Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell, The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules, The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain, The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel, eL19 may play a role in the last stages of translation initiation, in particular subunit joining and shedding/releasing factors

Belongs to the eukaryotic ribosomal protein eL19 family


This is 3-oxoacyl-[acyl-carrier-protein] reductase protein, from Fission yeast, contains 236 amino acids, locates in Mitochondrion.

Involved in biosynthesis of fatty acids in mitochondria

Belongs to the short-chain dehydrogenases/reductases (SDR) family


This is Protein transport protein sec61 subunit beta protein, from Fission yeast, contains 102 amino acids, is membrane-bound, locates in Endoplasmic reticulum.

Necessary for protein translocation in the endoplasmic reticulum


This is Uncharacterized protein C2G2.14 protein, from Fission yeast, contains 533 amino acids, locates in Nucleus.


This is Pre-mRNA-splicing factor cwf28 protein, from Fission yeast, contains 381 amino acids, locates in Nucleus.

Involved in spliceosome maturation and the first step of pre-mRNA splicing


This is Ribosomal RNA-processing protein 14-C protein, from Fission yeast, contains 233 amino acids, locates in Nucleus.


This is Probable NADH-ubiquinone oxidoreductase C947.15c, mitochondrial protein, from Fission yeast, contains 551 amino acids, locates in Mitochondrion.


This is Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] protein, from Fission yeast, contains 450 amino acids, is soluble, locates in Cytoplasm.

Belongs to the saccharopine dehydrogenase family


This is Probable sulfate permease C320.05 protein, from Fission yeast, contains 667 amino acids, is membrane-bound, locates in Endoplasmic reticulum.

Belongs to the SLC26A/SulP transporter (TC 2,A,53) family


This is Cytoplasmic 60S subunit biogenesis factor SPCC550.15c protein, from Fission yeast, contains 463 amino acids, has 4 C2H2-type Zinc finger, is soluble, locates in Cytoplasm.

Pre-60S-associated factor involved in the cytoplasmic maturation of the 60S subunit, Involved in the dissociation and recycling of other late pre-60S factors before newly synthesized large ribosomal subunits enter translation (By similarity)


This is Glucose-6-phosphate 1-dehydrogenase gcd1 protein, from Fission yeast, contains 475 amino acids, is soluble, locates in Cytoplasm.

Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis, The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis (By similarity)

Belongs to the glucose-6-phosphate dehydrogenase family


This is Peroxisomal membrane protein pex14 protein, from Fission yeast, contains 286 amino acids, is membrane-bound, locates in Peroxisome.

Component of the PEX13-PEX14 docking complex, a translocon channel that specifically mediates the import of peroxisomal cargo proteins bound to PEX5 receptor, The PEX13-PEX14 docking complex forms a large import pore which can be opened to a diameter of about 9 nm, Mechanistically, PEX5 receptor along with cargo proteins associates with the PEX14 subunit of the PEX13-PEX14 docking complex in the cytosol, leading to the insertion of the receptor into the organelle membrane with the concomitant translocation of the cargo into the peroxisome matrix


This is Mediator of RNA polymerase II transcription subunit 7 protein, from Fission yeast, contains 376 amino acids, locates in Nucleus.

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes, Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery, Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity)

Belongs to the Mediator complex subunit 7 family


This is Large ribosomal subunit protein uL13m protein, from Fission yeast, contains 157 amino acids, locates in Mitochondrion.

Belongs to the universal ribosomal protein uL13 family


This is Pentatricopeptide repeat-containing protein 2, mitochondrial protein, from Fission yeast, contains 432 amino acids, locates in Mitochondrion.

Mitochondrial RNA-binding protein that acts as a general translation factor