---
library_name: pyaging
tags:
- pyaging
- aging-clock
- biology
- dna-methylation
---

# cellpopage

CellPopAge is an elastic-net DNA-methylation clock using 42 selected CpGs to predict passage-based age of serially cultured adult primary human fibroblast populations and screen compounds that decelerate this measure.

Model weights retain the original authors' terms; the pyaging software license does not relicense them.

| | |
|---|---|
| **Predicts** | cell-population passage age |
| **Species** | Homo sapiens |
| **Tissue** | cultured fibroblasts |
| **Data type** | DNA methylation |
| **Model type** | elastic net regression |
| **Year** | 2024 |

## Use with pyaging

```python
import pyaging as pya

pya.pred.predict_age(adata, ["cellpopage"])
```

Browse every clock in the [pyaging Clock Catalogue](https://pyaging.readthedocs.io).

## Citation

Lujan, Celia, et al. "An expedited screening platform for the discovery of anti-ageing compounds in vitro and in vivo." Genome Medicine 16 (2024): 85.

https://doi.org/10.1186/s13073-024-01349-w