{
 "approved_by_author": "\u231b",
 "citation": "Li, X. et al. Derivation and validation of an epigenetic frailty risk score in population-based cohorts of older adults. Nature Communications 13, 5269 (2022).",
 "citations": 24,
 "citations_date": "2026-10-02",
 "clock_name": "dnamfili",
 "data_type": "DNA methylation",
 "doi": "https://doi.org/10.1038/s41467-022-32893-x",
 "journal": "Nature Communications",
 "last_author": "Hermann Brenner",
 "model_type": "LASSO regression",
 "n_features": 20,
 "notes": "Epigenetic frailty risk score (eFRS), a weighted 20-CpG whole-blood DNA-methylation score selected by LASSO from replicated frailty-associated loci.",
 "platform": [
  "Illumina EPIC",
  "Illumina 450K"
 ],
 "population": "older adults",
 "predicts": [
  "frailty risk"
 ],
 "research_only": null,
 "species": "Homo sapiens",
 "tissue": [
  "whole blood"
 ],
 "training_target": [
  "frailty"
 ],
 "unit": [
  "unitless"
 ],
 "version": "0.5.7",
 "year": 2022
}