---
library_name: pyaging
tags:
- pyaging
- aging-clock
- biology
- dna-methylation
---

# dnamstress

Whole-blood methylation score (MS stress) derived as a 211-CpG proxy for a composite of 13 stress-related measures.

Model weights retain the original authors' terms; the pyaging software license does not relicense them.

| | |
|---|---|
| **Predicts** | stress exposure |
| **Species** | Homo sapiens |
| **Tissue** | whole blood |
| **Data type** | DNA methylation |
| **Model type** | bootstrap-stabilized elastic net regression |
| **Year** | 2023 |

## Use with pyaging

```python
import pyaging as pya

pya.pred.predict_age(adata, ["dnamstress"])
```

Browse every clock in the [pyaging Clock Catalogue](https://pyaging.readthedocs.io).

## Citation

Jung, J., et al. “Additive Effects of Stress and Alcohol Exposure on Accelerated Epigenetic Aging in Alcohol Use Disorder.” Biological Psychiatry 93(4): 331–341 (2023).

https://doi.org/10.1016/j.biopsych.2022.06.036