---
library_name: pyaging
tags:
- pyaging
- aging-clock
- biology
- dna-methylation
---

# epitoc1

Relative mitotic-age score equal to the mean beta value across 385 polycomb-target promoter CpGs; it is not an absolute division count.

Model weights retain the original authors' terms; the pyaging software license does not relicense them.

| | |
|---|---|
| **Predicts** | mitotic age |
| **Species** | Homo sapiens |
| **Tissue** | multi-tissue, whole blood |
| **Data type** | DNA methylation |
| **Model type** | mean methylation aggregation |
| **Year** | 2016 |

## Use with pyaging

```python
import pyaging as pya

pya.pred.predict_age(adata, ["epitoc1"])
```

Browse every clock in the [pyaging Clock Catalogue](https://pyaging.readthedocs.io).

## Citation

Yang, Zhen, et al. "Correlation of an epigenetic mitotic clock with cancer risk." Genome Biology 17 (2016): 205.

https://doi.org/10.1186/s13059-016-1064-3