---
library_name: pyaging
tags:
- pyaging
- aging-clock
- biology
- dna-methylation
---

# hepatoxu

Ten-marker plasma cfDNA methylation logistic model producing the combined HCC diagnosis score (cd-score); this packaged model does not implement the separate eight-marker prognosis score.

Model weights retain the original authors' terms; the pyaging software license does not relicense them.

| | |
|---|---|
| **Predicts** | hepatocellular carcinoma |
| **Species** | Homo sapiens |
| **Tissue** | plasma cell-free DNA |
| **Data type** | DNA methylation |
| **Model type** | feature-selected logistic regression |
| **Year** | 2017 |

## Use with pyaging

```python
import pyaging as pya

pya.pred.predict_age(adata, ["hepatoxu"])
```

Browse every clock in the [pyaging Clock Catalogue](https://pyaging.readthedocs.io).

## Citation

Xu, R.-H., et al. “Circulating tumour DNA methylation markers for diagnosis and prognosis of hepatocellular carcinoma.” Nature Materials 16: 1155–1161 (2017).

https://doi.org/10.1038/nmat4997