---
library_name: pyaging
tags:
- pyaging
- aging-clock
- biology
- dna-methylation
---

# horvath2013

Pan-tissue DNAm-age predictor fitted by elastic net to a transformed chronological-age outcome and returned to the year scale; it uses 353 CpGs shared between the 27K and 450K arrays.

Model weights retain the original authors' terms; the pyaging software license does not relicense them.

| | |
|---|---|
| **Predicts** | chronological age |
| **Species** | Homo sapiens |
| **Tissue** | multi-tissue |
| **Data type** | DNA methylation |
| **Model type** | elastic net regression |
| **Year** | 2013 |

## Use with pyaging

```python
import pyaging as pya

pya.pred.predict_age(adata, ["horvath2013"])
```

Browse every clock in the [pyaging Clock Catalogue](https://pyaging.readthedocs.io).

## Citation

Horvath, S. DNA methylation age of human tissues and cell types. Genome Biology 14, R115 (2013).

https://doi.org/10.1186/gb-2013-14-10-r115