---
library_name: pyaging
tags:
- pyaging
- aging-clock
- biology
- dna-methylation
---

# petkovich

Mouse blood DNA-methylation age clock built by regression on reduced-representation bisulfite-sequencing CpGs, estimating biological age and shown to be slowed by lifespan-extending interventions such as caloric restriction and dwarfism.

Model weights retain the original authors' terms; the pyaging software license does not relicense them.

| | |
|---|---|
| **Predicts** | chronological age |
| **Species** | Mus musculus |
| **Tissue** | whole blood |
| **Data type** | DNA methylation |
| **Model type** | elastic net regression |
| **Year** | 2017 |

## Use with pyaging

```python
import pyaging as pya

pya.pred.predict_age(adata, ["petkovich"])
```

Browse every clock in the [pyaging Clock Catalogue](https://pyaging.readthedocs.io).

## Citation

Petkovich, Daniel A., et al. "Using DNA methylation profiling to evaluate biological age and longevity interventions." Cell metabolism 25.4 (2017): 954-960.

https://doi.org/10.1016/j.cmet.2017.03.016