---
library_name: pyaging
tags:
- pyaging
- aging-clock
- biology
- dna-methylation
---

# stubbs

Mouse multi-tissue RRBS age predictor: 17,992 common input loci are normalized and reduced to 329 nonzero clock sites, then quadratically calibrated.

Model weights retain the original authors' terms; the pyaging software license does not relicense them.

| | |
|---|---|
| **Predicts** | chronological age |
| **Species** | Mus musculus |
| **Tissue** | multi-tissue, liver, lung, heart, brain cortex, skeletal muscle, cerebellum, spleen |
| **Data type** | DNA methylation |
| **Model type** | quadratically calibrated elastic net regression |
| **Year** | 2017 |

## Use with pyaging

```python
import pyaging as pya

pya.pred.predict_age(adata, ["stubbs"])
```

Browse every clock in the [pyaging Clock Catalogue](https://pyaging.readthedocs.io).

## Citation

Stubbs, T. M., et al. “Multi-tissue DNA methylation age predictor in mouse.” Genome Biology 18: 68 (2017).

https://doi.org/10.1186/s13059-017-1203-5