---
library_name: pytorch
pipeline_tag: other
tags:
  - flow-matching
  - structure-based-drug-design
  - molecular-generation
  - pytorch
---

# LandFlow checkpoints

This repository stores the frozen PAFlow base checkpoint, its atom-number
predictor, and the LandFlow route-potential checkpoint used in the main
CrossDocked2020 experiment.

The LandFlow potential is a pairwise scalar model with 115,842 parameters. It
predicts a trajectory-derived future-quality cost and supplies a normalized
negative coordinate gradient during sampling. The PAFlow parameters remain
frozen.

Use these files with the matching GitHub release. SHA-256 checksums are listed
in `artifacts.json` in that repository.

This model is for research use in molecular generation. Generated structures
must not be interpreted as experimentally validated binders or medical advice.