{
  "source": "Researcher-supplied table and screening outcome, received 2026-11-10",
  "assayDate": null,
  "units": "μM",
  "unitProvenance": "Product concentration units carried forward from the original laboratory workbook for this assay series.",
  "submittedDesigns": 12,
  "activeDesigns": 9,
  "inactiveDesigns": 3,
  "reportedDesigns": 9,
  "screening": "Model-generated candidates were computationally screened; 12 selected designs were submitted for wet-lab testing. Nine showed PETase activity and three did not.",
  "conditions": null,
  "replicates": null,
  "rows": [
    {
      "id": "Y1",
      "name": "IsPETase",
      "kind": "wildtype",
      "tpa": 1034.0479,
      "mhet": 40.767,
      "total": 1074.8149,
      "length": 268,
      "sequenceSha256": "2eace7d7ed441600082b967d4c1398a9e7c5dbcf5c754178a8cdac97a0b1ac93",
      "fastaUrl": "/structures/wetlab-rcsb_5XG0_IsPETase.fasta"
    },
    {
      "id": "de1",
      "name": "DE1",
      "kind": "design",
      "tpa": 256.5466,
      "mhet": 185.2372,
      "total": 441.7838,
      "length": 284,
      "sequenceSha256": "915904060c2bd000f466d95c2eec5d3ccb53b133a1e877171001010603693e7b",
      "fastaUrl": "/structures/wetlab-de1.fasta"
    },
    {
      "id": "de2",
      "name": "DE2",
      "kind": "design",
      "tpa": 752.571,
      "mhet": 761.5821,
      "total": 1514.1531,
      "length": 279,
      "sequenceSha256": "421800d7574578af255aa700b2f346c284af2f05c1f7e58ef210d17093ee0ccd",
      "fastaUrl": "/structures/wetlab-de2.fasta"
    },
    {
      "id": "de3",
      "name": "DE3",
      "kind": "design",
      "tpa": 16.1355,
      "mhet": 4.861,
      "total": 20.9965,
      "length": 282,
      "sequenceSha256": "13616f5a11c7b52adaae1eefd112d9ca7d55fe4e8ce48d4bfc079423662839e3",
      "fastaUrl": "/structures/wetlab-de3.fasta"
    },
    {
      "id": "de4",
      "name": "DE4",
      "kind": "design",
      "tpa": 19.6139,
      "mhet": 1.5279,
      "total": 21.1418,
      "length": 286,
      "sequenceSha256": "5c31ac5e3b0f3a31d956d1ca0742afe9977e8453e03a9205a8b7935fa08c07c3",
      "fastaUrl": "/structures/wetlab-de4.fasta"
    },
    {
      "id": "de5",
      "name": "DE5",
      "kind": "design",
      "tpa": 25.0867,
      "mhet": 18.7743,
      "total": 43.861,
      "length": 280,
      "sequenceSha256": "abb7bae116b77fe0308d1a0db85046b952960c4ba2389f2835d897c87cf323fa",
      "fastaUrl": "/structures/wetlab-de5.fasta"
    },
    {
      "id": "de6",
      "name": "DE6",
      "kind": "design",
      "tpa": 121.7478,
      "mhet": 1.8291,
      "total": 123.5769,
      "length": 273,
      "sequenceSha256": "d70a416898bf971665518f79c85cbad5a628382ed5a074f8ce8077851aacc2c0",
      "fastaUrl": "/structures/wetlab-de6.fasta"
    },
    {
      "id": "de7",
      "name": "DE7",
      "kind": "design",
      "tpa": 114.5323,
      "mhet": 11.4136,
      "total": 125.946,
      "length": 280,
      "sequenceSha256": "444de5f614271844e6b17535e4d74d58cdadf500f1012a0742ea94cac9172771",
      "fastaUrl": "/structures/wetlab-de7.fasta"
    },
    {
      "id": "de8",
      "name": "DE8",
      "kind": "design",
      "tpa": 37.7339,
      "mhet": 7.6817,
      "total": 45.4156,
      "length": 286,
      "sequenceSha256": "5808975354da935f07e067e76a2d9603b513fe9950aa9edd9bb9b619274c4f1f",
      "fastaUrl": "/structures/wetlab-de8.fasta"
    },
    {
      "id": "de9",
      "name": "DE9",
      "kind": "design",
      "tpa": 72.1781,
      "mhet": 2.0316,
      "total": 74.2097,
      "length": 284,
      "sequenceSha256": "99fb968a621d6420a1b02e4668e8d13be3171800ee0762c50348fef279b8396b",
      "fastaUrl": "/structures/wetlab-de9.fasta"
    }
  ],
  "csvUrl": "/data/petase-assay.csv",
  "sourceSha256": "f7eaf1b74e0c1dc03f66f7a2b4e7a570fe655dfee272e731e948c3bf498b8a7c",
  "rounding": "Values preserve four decimals as supplied. DE7 components differ from its supplied total by 0.0001 μM due to rounding.",
  "generation": {
    "id": "de2",
    "predictionIndex0": 2890,
    "prompt": "Belongs to the alpha/beta hydrolase superfamily. Involved in the degradation of the plastic poly(ethylene terephthalate) (PET). Catalyzes the hydrolysis of PET to produce mono(2-hydroxyethyl) terephthalate (MHET) as the major product.",
    "sequenceSha256": "421800d7574578af255aa700b2f346c284af2f05c1f7e58ef210d17093ee0ccd",
    "generationId": "petase_lora_2891"
  },
  "structurePrediction": {
    "method": "ESMFold-v1",
    "job": "ouroboros-petase-nine-20261110-r1-14531184",
    "designCount": 9,
    "manifestSha256": "9b57decd8a6b6cd0e0849567abb44d15448043070b60ebb2c54214af76776ca1",
    "experimentalStructure": false
  }
}