{
  "category": "structure_retrieval",
  "benchmarks": [
    {
      "name": "PDB_TP53_STRUCTURE_AVAILABLE",
      "category": "structure_retrieval",
      "description": "Human p53 must resolve to at least one experimental PDB structure.",
      "input": {
        "accession": "P04637"
      },
      "section": "alphafold",
      "expected_output": {
        "structure_available": true
      },
      "tolerance": {
        "structure_available": 0
      },
      "ground_truth": "Multiple human p53 PDB entries exist (e.g. 4MZR, 1TUP).",
      "citation": "Berman H.M. et al. Nucleic Acids Res. 2000 (wwPDB); Cho Y. et al. Science 1994.",
      "source": "RCSB PDB",
      "stage": "curated",
      "difficulty": "easy",
      "version": 1
    },
    {
      "name": "ALPHAFOLD_TP53_AVAILABLE",
      "category": "structure_retrieval",
      "description": "AlphaFold DB must have a predicted structure for human p53 (AF-P04637-F1).",
      "input": {
        "accession": "P04637"
      },
      "section": "alphafold",
      "expected_output": {
        "structure_available": true
      },
      "tolerance": {
        "structure_available": 0
      },
      "ground_truth": "AlphaFold DB predicts p53: AF-P04637-F1-model_v4.",
      "citation": "Jumper J. et al. Nature 2021; Varadi M. et al. Nucleic Acids Res. 2022.",
      "source": "AlphaFold DB",
      "stage": "curated",
      "difficulty": "easy",
      "version": 1
    },
    {
      "name": "ALPHAFOLD_INSULIN_AVAILABLE",
      "category": "structure_retrieval",
      "description": "AlphaFold DB must have a predicted structure for human insulin (AF-P01308-F1).",
      "input": {
        "accession": "P01308"
      },
      "section": "alphafold",
      "expected_output": {
        "structure_available": true
      },
      "tolerance": {
        "structure_available": 0
      },
      "ground_truth": "AlphaFold DB predicts insulin: AF-P01308-F1-model_v4.",
      "citation": "Jumper J. et al. Nature 2021; Varadi M. et al. Nucleic Acids Res. 2022.",
      "source": "AlphaFold DB",
      "stage": "curated",
      "difficulty": "easy",
      "version": 1
    }
  ]
}