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PIVOT

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biology
single-cell
perturbation-prediction
flow-matching
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PIVOT
File size: 2,201 Bytes
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{
  "ranked": [
    {
      "label": "CEBPA",
      "genes": [
        "CEBPA"
      ],
      "operation": "activation",
      "predicted_reward": -5.897198677062988
    },
    {
      "label": "ATL1",
      "genes": [
        "ATL1"
      ],
      "operation": "activation",
      "predicted_reward": -5.897573471069336
    },
    {
      "label": "CEBPA_ZC3HAV1",
      "genes": [
        "CEBPA",
        "ZC3HAV1"
      ],
      "operation": "activation",
      "predicted_reward": -5.897652626037598
    },
    {
      "label": "IGDCC3",
      "genes": [
        "IGDCC3"
      ],
      "operation": "activation",
      "predicted_reward": -5.898065090179443
    },
    {
      "label": "CEBPE_ZC3HAV1",
      "genes": [
        "CEBPE",
        "ZC3HAV1"
      ],
      "operation": "activation",
      "predicted_reward": -5.898181915283203
    }
  ],
  "search": "guidance",
  "reward": "centroid",
  "target_file": "target.npy",
  "control_cell_ids": [
    "CGTGTAATCCATGCTC",
    "GGGACCTGTATGAAAC",
    "ATCATGGTCTGCCAGG",
    "CATCGAATCAGTCAGT",
    "TTCTCAAAGCTCCTTC",
    "TGGCTGGAGACCTAGG",
    "CGTGAGCTCAACTCTT",
    "GATGAGGGTGACCAAG",
    "TAAACCGGTAATCACC",
    "CTACATTGTTAAGAAC",
    "GATTCAGCAACACCCG",
    "ACGATGTAGGGATACC",
    "CTAAGACGTCGAACAG",
    "TAAGTGCGTGGGTCAA",
    "AGTGGGACAGGCTGAA",
    "ACGCCGAGTGAAATCA"
  ],
  "data_meta": {
    "reference_fraction": 0.1,
    "protocol": "split-first-v1",
    "dataset": "norman",
    "name": "norman",
    "operation": "activation",
    "control_label": "control",
    "sep": "_",
    "split": "perturbation",
    "seed": 0,
    "input_scale": "counts",
    "raw_sha256": "21bd3c00b7f243d998aa9ca616490b45bf1b4ba9934d501190a867ddad982dae",
    "raw_file": "norman_small.h5ad",
    "n_cells": 920,
    "n_control": 120,
    "n_hvg": 201,
    "n_pca": 10,
    "pca_explained_var": 0.5626983046531677,
    "mmd_gamma": 0.06974897265608301,
    "fit_cell_ids_sha256": "5ff57f6222cd8d3e4dd6b7fa658c8599cf6eb4b553a607ad9100a7fc240f9f22",
    "selection": {
      "max_cells": null,
      "max_per_group": null,
      "max_groups": null
    },
    "software": {
      "scanpy": "1.12.4",
      "anndata": "0.13.3.post0"
    }
  }
}