Update README.md

README.md

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-# Healdette: Ancestry-Aware Antibody Generator
+# Codette Antibody Pipeline
 
-**Healdette** is a fully transparent, ethics-filtered antibody generation pipeline built by Jonathan Harrison (Raiff1982). It is the first AI system to integrate:
+The **Codette Antibody Pipeline** is an ethics-aware, ancestry-informed, transparent antibody and nanobody design system.
+It fuses real biophysical models, transformer-based sequence generation, structural simulation, and cultural personalization.
 
-- Real transformer-based antibody design
-- Ethical rejection memory and tracelines
-- Cultural/ancestry-aware HLA and immune tuning
-- Personalization using immune profile, prior exposure, and metabolic rate
+## Features
 
-All computations are traceable. No placeholder logic. No black box.
+- ✅ Real transformer model for protein generation (ProtGPT2)
+- ✅ Biophysical analysis with BioPython
+- ✅ Multi-perspective reasoning (Newton, Da Vinci, Quantum, Ethical)
+- ✅ Ethical tracelines and rejection memory
+- ✅ Personalized output based on ancestry (Native, Irish, others)
+- ✅ JSON and human-readable TXT summary outputs
+- ✅ No placeholders. Every computation is real.
+
+## Installation
+
+```bash
+pip install -r requirements.txt
+```
+
+## Usage
+
+```bash
+python main.py
+```
+
+## Input
+
+Edit `main.py` to provide your target protein sequence and patient context (ancestry, immune profile, etc.).
+
+## Output
+
+- `output/codette_antibody_designs_*.json`: Full metadata-rich output
+- `output/codette_antibody_summary_*.txt`: Transparent, readable design summary
+
+## License
+
+MIT License. Use responsibly. No closed-source derivatives allowed without attribution.
+
+## Author
+
+Jonathan Harrison (Raiff1982) + Codette
 
 **DOI:** [10.57967/hf/5917](https://doi.org/10.57967/hf/5917)  
 **License:** MIT — with attribution, no dual-use harm permitted.