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- ---
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- license: mit
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- ---
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-
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- # Models for MF-Design
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-
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- This repository hosts the pre-trained model checkpoints for the paper **"Repurposing AlphaFold3-like Protein Folding Models for Antibody Sequence and Structure Co-design" (MF-Design)**.
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-
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- The main code repository can be found at [MF-Design](https://github.com/yangnianzu0515/mfdesign).
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-
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- ## Directory Structure
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-
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- The `./model` directory contains various trained model checkpoints.
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-
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- The following files are sourced from the [Boltz-1](https://github.com/jwohlwend/boltz) repository:
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- * `boltz1.ckpt`
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- * `boltz1_conf.ckpt`
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- * `ccd.pkl`
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- * `symmetry.pkl`
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-
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- We provide the following checkpoints for our MFDesign models:
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-
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- * **MFDesign-D**: Checkpoints for all four training stages are provided.
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- * **MFDesign-C**: The checkpoint for the final stage is provided.
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-
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- For the final stage of both `MFDesign-D` and `MFDesign-C`, we also provide an additional checkpoint for models that were trained without epitope information.
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-
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- ## Citation
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-
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- If you use MFDesign in your research, please cite our paper:
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-
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- ```bibtex
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- @article{mf_design_2025,
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- title={Repurposing AlphaFold3-like Protein Folding Models for Antibody Sequence and Structure Co-design},
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- author={Nianzu Yang and Songlin Jiang and Jian Ma and Huaijin Wu and Shuangjia Zheng and Wengong Jin and Junchi Yan},
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- journal={ICLR 2025 GEM Workshop},
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- year={2025},
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- url={[https://openreview.net/pdf/fa449e7c0c04e638dab5d8b500e85cbb30f29694.pdf](https://openreview.net/pdf/fa449e7c0c04e638dab5d8b500e85cbb30f29694.pdf)}
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  }
 
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+ ---
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+ license: mit
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+ ---
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+
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+ # Models for MF-Design
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+
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+ This repository hosts the pre-trained model checkpoints for the paper **"Repurposing AlphaFold3-like Protein Folding Models for Antibody Sequence and Structure Co-design" (MF-Design)**.
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+
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+ The main code repository can be found at [MF-Design](https://github.com/yangnianzu0515/mfdesign).
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+
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+ ## Directory Structure
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+
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+ The `./model` directory contains various trained model checkpoints.
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+
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+ The following files are sourced from the [Boltz-1](https://github.com/jwohlwend/boltz) repository:
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+ * `boltz1.ckpt`
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+ * `boltz1_conf.ckpt`
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+ * `ccd.pkl`
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+ * `symmetry.pkl`
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+
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+ We provide the following checkpoints for our MFDesign models:
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+
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+ * **MFDesign-D**: Checkpoints for all four training stages are provided.
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+ * **MFDesign-C**: The checkpoint for the final stage is provided.
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+
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+ For the final stage of both `MFDesign-D` and `MFDesign-C`, we also provide an additional checkpoint for models that were trained without epitope information.
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+
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+ ## Citation
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+
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+ If you use MFDesign in your research, please cite our paper:
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+
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+ ```bibtex
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+ @article{mf_design_2025,
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+ title={Repurposing AlphaFold3-like Protein Folding Models for Antibody Sequence and Structure Co-design},
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+ author={Nianzu Yang and Songlin Jiang and Jian Ma and Huaijin Wu and Shuangjia Zheng and Wengong Jin and Junchi Yan},
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+ journal={NeurIPS 2025},
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+ year={2025},
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+ url={[https://openreview.net/pdf?id=M96edY67nS)}
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  }