Delete data/embeddings/probe_ksep
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data/embeddings/probe_ksep/README.md
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# Embedding name: PROBE-KSEP
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- Modality: Protein representation
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- Embedding source URL: https://huggingface.co/spaces/HUBioDataLab/PROBE
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- Original model/code URL: https://github.com/HUBioDataLab/PROBE
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## Public files
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- `embeddings.npz`: compressed NumPy archive containing the embedding matrix under key `embeddings`.
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- `genes.tsv`: row metadata table. Row order matches the embedding matrix.
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- `metadata.json`: machine-readable provenance and processing metadata.
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## Matrix
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- Shape: `18,801 genes × 400 dimensions`
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- Dtype: `float32`
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## Detailed processing notes
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### Source and interpretation
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This embedding is one PROBE human UniProt representation table standardized into the shared gene-embedding resource.
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This is a KSEP protein representation from the PROBE archive.
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The source file used for this component was `KSEP_UNIPROT_HUMAN.csv` from the official PROBE human UniProt representation archive.
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### Provenance fields
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source_name: PROBE-KSEP
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original_model_or_method: PROBE human UniProt representation archive
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input_data_type: official PROBE human UniProt CSV representation table
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input_source_file: KSEP_UNIPROT_HUMAN.csv
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source_download_or_app_page: https://huggingface.co/spaces/HUBioDataLab/PROBE
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source_code_page: https://github.com/HUBioDataLab/PROBE
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raw_source_folder: ~/data/raw_embeddings/probe_official/human_representation_vectors/revision-1/
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source_identifier_type: UniProt Entry accession
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mapping_identifier_type: UniProt accession matched to enriched master_gene_table.csv UniProt fields
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source_rows_or_entries: 18,801 mapped source genes
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final_mapped_genes: 18,801
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model_or_feature_dimension: 400
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training_or_finetuning: none
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final_embedding_dtype: float32
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### Mapping and processing decisions
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Each PROBE CSV uses a UniProt accession in the `Entry` column. Source entries were cleaned to their canonical accession base by removing isoform suffixes when present.
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Cleaned UniProt accessions were mapped to master_gene_table.csv using `uniprot_id`, `hgnc_uniprot_ids`, and `map_uniprot_ids_all`. Only unique UniProt-to-master mappings were accepted. Ambiguous UniProt accessions were excluded. Duplicate source proteins mapping to the same final master-table gene were averaged within that gene.
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### Processing workflow
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For this PROBE embedding:
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1. Read `KSEP_UNIPROT_HUMAN.csv` from the PROBE human representation archive.
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2. Use the `Entry` column as the source UniProt accession.
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3. Remove isoform suffixes where present to obtain the canonical UniProt accession base.
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4. Map source UniProt accessions to master_gene_table.csv through enriched UniProt fields.
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5. Exclude unmapped and ambiguous UniProt accessions.
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6. Average duplicate source rows only when they map to the same final master-table gene.
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7. Save the final matrix as float32.
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### Important implementation decisions
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All PROBE embeddings use the same mapping logic, so differences between PROBE outputs reflect the source representation type rather than different gene-mapping rules.
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### Summary of final mapping:
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Source identifiers / source rows or entries: 18,801 mapped source genes
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Dimensions: 400
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Final mapped genes: 18,801
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Master table rows: 20,097
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Master coverage: 93.55%
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Mapping strategy: UniProt Entry accession mapping through enriched master table
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Ambiguous UniProt accessions: excluded
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Duplicate final mappings averaged: yes
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<!-- BEGIN CATALOG NORMALIZATION: LEGACY METADATA -->
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## Processing and provenance metadata
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This section preserves information moved out of `metadata.json` during catalog normalization. The loading-facing metadata is intentionally compact; detailed source, mapping, processing, quality-control, and reproducibility records remain here.
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Source catalog commit: `ab37742040d20b523aebd188d3079871a0c2b534`.
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### Canonicalized field names
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| Previous field | Compact metadata field |
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| --- | --- |
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| `embedding_name` | `display_name` |
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| `source_identifier_type` | `original_identifier_type` |
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| `mapping_strategy` | `mapping_method` |
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| `num_genes` | `n_genes` |
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| `embedding_dimension` | `n_dimensions` |
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| `matrix_shape[0]` | `n_genes` |
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| `matrix_shape[1]` | `n_dimensions` |
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| `original_model_or_method` | `original_method` |
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| `download_source` | `input_data_source` |
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### Derived standardized fields
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- `species` was set to `Homo sapiens` from the validated human Ensembl `ENSG` identifier namespace.
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- `master_coverage_fraction` was computed as `n_genes / 20097`.
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### Legacy processing and provenance record
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```json
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{
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"all_zero_rows": {
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"count": 23,
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"documented": true,
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"expected": true,
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"reason": "These exact all-zero vectors were already present in the official PROBE source file KSEP_UNIPROT_HUMAN.csv. They were retained unchanged during identifier mapping and standardization to preserve the released source representation and matrix-to-gene alignment. They were not created through padding, missing-value replacement, or imputation.",
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"source_file": "KSEP_UNIPROT_HUMAN.csv",
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"source_provenance_column": "source_keys_examples",
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"source_verification": "All 23 final all-zero rows were traced through source_keys_examples to official PROBE source vectors that were also exactly all-zero."
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},
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"counts": {
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"ambiguous_source_rows": 183,
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"duplicate_final_mappings_averaged": 29,
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"final_dimensions": 400,
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"final_mapped_genes": 18801,
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"mapped_source_rows_before_duplicate_collapse": 18832,
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"master_rows": 20097,
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"source_dimensions": 400,
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"source_rows": 20199,
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"unmapped_source_rows": 1184
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},
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"coverage": {
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"master_gene_coverage_fraction": 0.93551276309897,
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"source_row_mapping_fraction": 0.9323233823456607
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},
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"former_processing_embedding_id": "probe_ksep_v1_1",
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"mapping_method_counts": {
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"uniprot_accession_exact_unique": 18801
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},
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"public_file_structure": {
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"embeddings": "embeddings.npz",
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"genes": "genes.tsv",
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"metadata": "metadata.json",
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"readme": "README.md"
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},
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"sequence_and_reference_provenance": {
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"input_sequence_source": "PROBE human UniProt representation archive",
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"input_sequence_type": "protein sequence-derived representation",
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"sequence_reference_status": "PROBE archive provenance recorded; exact UniProt release to verify from original PROBE documentation if needed",
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"source_identifier": "UniProt accession in Entry column",
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"species": "human"
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},
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"source_embedding": "PROBE_KSEP"
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}
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```
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<!-- END CATALOG NORMALIZATION: LEGACY METADATA -->
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data/embeddings/probe_ksep/embeddings.npz
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version https://git-lfs.github.com/spec/v1
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oid sha256:23a3d35bf9eb21dacf23b15ed756f9ac4ddfc550bc2f6303d9d5ff65cc2ea841
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size 23775898
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data/embeddings/probe_ksep/genes.tsv
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The diff for this file is too large to render.
See raw diff
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data/embeddings/probe_ksep/metadata.json
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{
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"embedding_id": "probe_ksep",
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"display_name": "ksep",
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"modality": "protein sequence / protein representation from PROBE human UniProt archive",
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"species": "Homo sapiens",
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"original_identifier_type": "UniProt accession",
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"mapping_method": "Exact UniProt accession mapping to master_gene_table_v1_1_enriched.csv using uniprot_id, hgnc_uniprot_ids, and map_uniprot_ids_all. Only unique mappings are accepted. Duplicate source rows mapping to the same final master gene are averaged.",
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"n_genes": 18801,
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"n_dimensions": 400,
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"master_coverage_fraction": 0.93551276309897,
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"original_method": "KSEP",
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"embedding_generated_by": "PROBE authors / original PROBE human representation archive",
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"input_data_source": "Official PROBE human_representation_vectors.tar.gz archive from Zenodo record 5795850 plus official HUBioDataLab/PROBE repository"
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}
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