Clean public folder structure and master table filenames
Browse filesThis view is limited to 50 files because it contains too many changes. See raw diff
- .gitattributes +1 -0
- README.md +2 -2
- data/embedding_id_rename_map.csv +69 -0
- data/embeddings/alphagenome_tss1mb_regulatory_tracksummary_pca256/README.md +74 -0
- data/embeddings/{alphagenome_tss1mb_regulatory_tracksummary_pca256_v1_1/alphagenome_tss1mb_regulatory_tracksummary_pca256_v1_1_embeddings.npz → alphagenome_tss1mb_regulatory_tracksummary_pca256/embeddings.npz} +0 -0
- data/embeddings/{alphagenome_tss1mb_regulatory_tracksummary_pca256_v1_1/alphagenome_tss1mb_regulatory_tracksummary_pca256_v1_1_genes.tsv → alphagenome_tss1mb_regulatory_tracksummary_pca256/genes.tsv} +0 -0
- data/embeddings/{alphagenome_tss1mb_regulatory_tracksummary_pca256_v1_1/alphagenome_tss1mb_regulatory_tracksummary_pca256_v1_1_metadata.json → alphagenome_tss1mb_regulatory_tracksummary_pca256/metadata.json} +10 -2
- data/embeddings/basenji2_tss_131kb_human_central3/README.md +77 -0
- data/embeddings/{basenji2_tss_131kb_human_central3_v1_1/basenji2_tss_131kb_human_central3_v1_1_embeddings.npz → basenji2_tss_131kb_human_central3/embeddings.npz} +0 -0
- data/embeddings/{basenji2_tss_131kb_human_central3_v1_1/basenji2_tss_131kb_human_central3_v1_1_genes.tsv → basenji2_tss_131kb_human_central3/genes.tsv} +0 -0
- data/embeddings/{basenji2_tss_131kb_human_central3_v1_1/basenji2_tss_131kb_human_central3_v1_1_metadata.json → basenji2_tss_131kb_human_central3/metadata.json} +10 -2
- data/embeddings/biobert_gene_protein_summary/README.md +75 -0
- data/embeddings/{biobert_gene_protein_summary_v1_1/biobert_gene_protein_summary_v1_1_embeddings.npz → biobert_gene_protein_summary/embeddings.npz} +0 -0
- data/embeddings/{biobert_gene_protein_summary_v1_1/biobert_gene_protein_summary_v1_1_genes.tsv → biobert_gene_protein_summary/genes.tsv} +0 -0
- data/embeddings/{biobert_gene_protein_summary_v1_1/biobert_gene_protein_summary_v1_1_metadata.json → biobert_gene_protein_summary/metadata.json} +10 -2
- data/embeddings/bioconceptvec_cbow/README.md +75 -0
- data/embeddings/{bioconceptvec_cbow_v1_1/bioconceptvec_cbow_v1_1_embeddings.npz → bioconceptvec_cbow/embeddings.npz} +0 -0
- data/embeddings/{bioconceptvec_cbow_v1_1/bioconceptvec_cbow_v1_1_genes.tsv → bioconceptvec_cbow/genes.tsv} +0 -0
- data/embeddings/{bioconceptvec_cbow_v1_1/bioconceptvec_cbow_v1_1_metadata.json → bioconceptvec_cbow/metadata.json} +10 -2
- data/embeddings/bioconceptvec_fasttext/README.md +75 -0
- data/embeddings/{bioconceptvec_fasttext_v1_1/bioconceptvec_fasttext_v1_1_embeddings.npz → bioconceptvec_fasttext/embeddings.npz} +0 -0
- data/embeddings/{bioconceptvec_fasttext_v1_1/bioconceptvec_fasttext_v1_1_genes.tsv → bioconceptvec_fasttext/genes.tsv} +0 -0
- data/embeddings/{bioconceptvec_fasttext_v1_1/bioconceptvec_fasttext_v1_1_metadata.json → bioconceptvec_fasttext/metadata.json} +10 -2
- data/embeddings/bioconceptvec_glove/README.md +75 -0
- data/embeddings/{bioconceptvec_glove_v1_1/bioconceptvec_glove_v1_1_embeddings.npz → bioconceptvec_glove/embeddings.npz} +0 -0
- data/embeddings/{bioconceptvec_glove_v1_1/bioconceptvec_glove_v1_1_genes.tsv → bioconceptvec_glove/genes.tsv} +0 -0
- data/embeddings/{bioconceptvec_glove_v1_1/bioconceptvec_glove_v1_1_metadata.json → bioconceptvec_glove/metadata.json} +10 -2
- data/embeddings/bioconceptvec_skipgram/README.md +75 -0
- data/embeddings/{bioconceptvec_skipgram_v1_1/bioconceptvec_skipgram_v1_1_embeddings.npz → bioconceptvec_skipgram/embeddings.npz} +0 -0
- data/embeddings/{bioconceptvec_skipgram_v1_1/bioconceptvec_skipgram_v1_1_genes.tsv → bioconceptvec_skipgram/genes.tsv} +0 -0
- data/embeddings/{bioconceptvec_skipgram_v1_1/bioconceptvec_skipgram_v1_1_metadata.json → bioconceptvec_skipgram/metadata.json} +10 -2
- data/embeddings/cmap_gse106127_cgs_mean_landmark978_zscore/README.md +73 -0
- data/embeddings/{cmap_gse106127_cgs_mean_landmark978_zscore_v1_1/cmap_gse106127_cgs_mean_landmark978_zscore_v1_1_embeddings.npz → cmap_gse106127_cgs_mean_landmark978_zscore/embeddings.npz} +0 -0
- data/embeddings/{cmap_gse106127_cgs_mean_landmark978_zscore_v1_1/cmap_gse106127_cgs_mean_landmark978_zscore_v1_1_genes.tsv → cmap_gse106127_cgs_mean_landmark978_zscore/genes.tsv} +0 -0
- data/embeddings/{cmap_gse106127_cgs_mean_landmark978_zscore_v1_1/cmap_gse106127_cgs_mean_landmark978_zscore_v1_1_metadata.json → cmap_gse106127_cgs_mean_landmark978_zscore/metadata.json} +9 -1
- data/embeddings/deepnf_string_v12_ppmi_svd_fusion/README.md +79 -0
- data/embeddings/{deepnf_string_v12_ppmi_svd_fusion_v1_1/deepnf_string_v12_ppmi_svd_fusion_v1_1_embeddings.npz → deepnf_string_v12_ppmi_svd_fusion/embeddings.npz} +0 -0
- data/embeddings/{deepnf_string_v12_ppmi_svd_fusion_v1_1/deepnf_string_v12_ppmi_svd_fusion_v1_1_genes.tsv → deepnf_string_v12_ppmi_svd_fusion/genes.tsv} +0 -0
- data/embeddings/{deepnf_string_v12_ppmi_svd_fusion_v1_1/deepnf_string_v12_ppmi_svd_fusion_v1_1_metadata.json → deepnf_string_v12_ppmi_svd_fusion/metadata.json} +9 -1
- data/embeddings/deepsea_tss_1kb_epigenomic_probs/README.md +79 -0
- data/embeddings/{deepsea_tss_1kb_epigenomic_probs_v1_1/deepsea_tss_1kb_epigenomic_probs_v1_1_embeddings.npz → deepsea_tss_1kb_epigenomic_probs/embeddings.npz} +0 -0
- data/embeddings/{deepsea_tss_1kb_epigenomic_probs_v1_1/deepsea_tss_1kb_epigenomic_probs_v1_1_genes.tsv → deepsea_tss_1kb_epigenomic_probs/genes.tsv} +0 -0
- data/embeddings/{deepsea_tss_1kb_epigenomic_probs_v1_1/deepsea_tss_1kb_epigenomic_probs_v1_1_metadata.json → deepsea_tss_1kb_epigenomic_probs/metadata.json} +10 -2
- data/embeddings/depmap_crispr_gene_effect_pca256/README.md +73 -0
- data/embeddings/{depmap_crispr_gene_effect_pca256_v1_1/depmap_crispr_gene_effect_pca256_v1_1_embeddings.npz → depmap_crispr_gene_effect_pca256/embeddings.npz} +0 -0
- data/embeddings/{depmap_crispr_gene_effect_pca256_v1_1/depmap_crispr_gene_effect_pca256_v1_1_genes.tsv → depmap_crispr_gene_effect_pca256/genes.tsv} +0 -0
- data/embeddings/{depmap_crispr_gene_effect_pca256_v1_1/depmap_crispr_gene_effect_pca256_v1_1_metadata.json → depmap_crispr_gene_effect_pca256/metadata.json} +9 -1
- data/embeddings/dnabert2_117m_cds/README.md +69 -0
- data/embeddings/{dnabert2_117m_cds_v1_1/dnabert2_117m_cds_v1_1_embeddings.npz → dnabert2_117m_cds/embeddings.npz} +0 -0
- data/embeddings/{dnabert2_117m_cds_v1_1/dnabert2_117m_cds_v1_1_genes.tsv → dnabert2_117m_cds/genes.tsv} +0 -0
.gitattributes
CHANGED
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@@ -59,3 +59,4 @@ saved_model/**/* filter=lfs diff=lfs merge=lfs -text
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*.mp4 filter=lfs diff=lfs merge=lfs -text
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*.webm filter=lfs diff=lfs merge=lfs -text
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data/master_gene_table_v1_1_enriched.csv filter=lfs diff=lfs merge=lfs -text
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*.mp4 filter=lfs diff=lfs merge=lfs -text
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*.webm filter=lfs diff=lfs merge=lfs -text
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data/master_gene_table_v1_1_enriched.csv filter=lfs diff=lfs merge=lfs -text
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data/master_gene_table.csv filter=lfs diff=lfs merge=lfs -text
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README.md
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- `data/manifest.csv`
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- `data/manifest.parquet`
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- `data/
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- `data/
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- `data/embeddings/<embedding_id>/<embedding_id>_embeddings.npz`
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- `data/embeddings/<embedding_id>/<embedding_id>_genes.tsv`
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- `data/embeddings/<embedding_id>/<embedding_id>_metadata.json`
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- `data/manifest.csv`
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- `data/manifest.parquet`
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- `data/master_gene_table.csv`
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- `data/master_gene_table.parquet`
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- `data/embeddings/<embedding_id>/<embedding_id>_embeddings.npz`
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- `data/embeddings/<embedding_id>/<embedding_id>_genes.tsv`
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- `data/embeddings/<embedding_id>/<embedding_id>_metadata.json`
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data/embedding_id_rename_map.csv
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former_processing_embedding_id,embedding_id
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alphagenome_tss1mb_regulatory_tracksummary_pca256_v1_1,alphagenome_tss1mb_regulatory_tracksummary_pca256
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| 3 |
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basenji2_tss_131kb_human_central3_v1_1,basenji2_tss_131kb_human_central3
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| 4 |
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biobert_gene_protein_summary_v1_1,biobert_gene_protein_summary
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| 5 |
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bioconceptvec_cbow_v1_1,bioconceptvec_cbow
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| 6 |
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bioconceptvec_fasttext_v1_1,bioconceptvec_fasttext
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| 7 |
+
bioconceptvec_glove_v1_1,bioconceptvec_glove
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| 8 |
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bioconceptvec_skipgram_v1_1,bioconceptvec_skipgram
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| 9 |
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cmap_gse106127_cgs_mean_landmark978_zscore_v1_1,cmap_gse106127_cgs_mean_landmark978_zscore
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| 10 |
+
deepnf_string_v12_ppmi_svd_fusion_v1_1,deepnf_string_v12_ppmi_svd_fusion
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| 11 |
+
deepsea_tss_1kb_epigenomic_probs_v1_1,deepsea_tss_1kb_epigenomic_probs
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| 12 |
+
depmap_crispr_gene_effect_pca256_v1_1,depmap_crispr_gene_effect_pca256
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| 13 |
+
dnabert2_117m_cds_v1_1,dnabert2_117m_cds
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| 14 |
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enformer_tss_393kb_human_central3_v1_1,enformer_tss_393kb_human_central3
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| 15 |
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esm2_v1_1,esm2
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| 16 |
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frogs_archs4_256_v1_1,frogs_archs4_256
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| 17 |
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gene2vec_v1_1,gene2vec
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| 18 |
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genecompass_base_gene_token_v1_1,genecompass_base_gene_token
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| 19 |
+
geneformer_v2_316m_v1_1,geneformer_v2_316m
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| 20 |
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genept_ada_v1_1_conservative,genept_ada_conservative
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| 21 |
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genept_model3_gene_protein_v1_1_conservative,genept_model3_gene_protein_conservative
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| 22 |
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gtex_tissue_median_log1p_zscore_v1_1,gtex_tissue_median_log1p_zscore
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| 23 |
+
helix_mrna_full_transcript_v1_1,helix_mrna_full_transcript
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| 24 |
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hetionet_nonppi_biomedical_context_tfidf_svd256_v1_1,hetionet_nonppi_biomedical_context_tfidf_svd256
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| 25 |
+
hpa_normal_ihc_tissue_level_zscore_v1_1,hpa_normal_ihc_tissue_level_zscore
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| 26 |
+
hpa_subcellular_location_multihot_zscore_v1_1,hpa_subcellular_location_multihot_zscore
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| 27 |
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hyenadna_medium_160k_cds_v1_1,hyenadna_medium_160k_cds
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| 28 |
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mahi_all_contexts_mean_v1_1,mahi_all_contexts_mean
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| 29 |
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mahi_global_v1_1,mahi_global
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| 30 |
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mashup_string_v1_1,mashup_string
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| 31 |
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msa_transformer_depth1_uniprot_human_v1_1,msa_transformer_depth1_uniprot_human
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| 32 |
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newt_archs4_256_v1_1,newt_archs4_256
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| 33 |
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newt_cellnet_v1_1,newt_cellnet
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| 34 |
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newt_go_256_v1_1,newt_go_256
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| 35 |
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newt_go_graph_v1_1,newt_go_graph
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| 36 |
+
newt_msigdb_bundle_v1_1,newt_msigdb_bundle
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| 37 |
+
node2vec_consensus_ppi_v1_1,node2vec_consensus_ppi
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| 38 |
+
nt_v2_500m_multispecies_cds_v1_1,nt_v2_500m_multispecies_cds
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| 39 |
+
opa2vec_goa_human_v1_1,opa2vec_goa_human
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| 40 |
+
orthrus_base_4track_full_transcript_v1_1,orthrus_base_4track_full_transcript
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| 41 |
+
primekg_nonppi_biomedical_context_tfidf_svd256_v1_1,primekg_nonppi_biomedical_context_tfidf_svd256
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| 42 |
+
probe_aac_v1_1,probe_aac
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| 43 |
+
probe_albert_v1_1,probe_albert
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| 44 |
+
probe_apaac_v1_1,probe_apaac
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| 45 |
+
probe_bert_bfd_v1_1,probe_bert_bfd
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| 46 |
+
probe_bert_pfam_v1_1,probe_bert_pfam
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| 47 |
+
probe_blast_v1_1,probe_blast
|
| 48 |
+
probe_cpc_prot_v1_1,probe_cpc_prot
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| 49 |
+
probe_esmb1_v1_1,probe_esmb1
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| 50 |
+
probe_gene2vec_uniprot_v1_1,probe_gene2vec_uniprot
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| 51 |
+
probe_hmmer_v1_1,probe_hmmer
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| 52 |
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probe_ksep_v1_1,probe_ksep
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| 53 |
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probe_learned_vec_v1_1,probe_learned_vec
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| 54 |
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probe_mut2vec_v1_1,probe_mut2vec
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| 55 |
+
probe_pfam_v1_1,probe_pfam
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| 56 |
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probe_protvec_v1_1,probe_protvec
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| 57 |
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probe_seqvec_v1_1,probe_seqvec
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| 58 |
+
probe_t5_v1_1,probe_t5
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| 59 |
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probe_tcga_embedding_v1_1,probe_tcga_embedding
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| 60 |
+
probe_unirep_v1_1,probe_unirep
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| 61 |
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probe_xlnet_v1_1,probe_xlnet
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| 62 |
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pubmedbert_gene_protein_summary_v1_1,pubmedbert_gene_protein_summary
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| 63 |
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rnafm_full_transcript_v1_1,rnafm_full_transcript
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| 64 |
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scfoundation_gene_pos_v1_1,scfoundation_gene_pos
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| 65 |
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scgpt_pancancer_v1_1,scgpt_pancancer
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| 66 |
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scgpt_whole_human_v1_1,scgpt_whole_human
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| 67 |
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scprint_medium_v1_5_gene_v1_1,scprint_medium_v1_5_gene
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| 68 |
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spliceai_canonical_splice_site_profile_v1_1,spliceai_canonical_splice_site_profile
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| 69 |
+
uce_33l_v1_1,uce_33l
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data/embeddings/alphagenome_tss1mb_regulatory_tracksummary_pca256/README.md
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# AlphaGenome-TSS1Mb-regulatoryTrackSummary-PCA256-v1.1
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Embedding ID: `alphagenome_tss1mb_regulatory_tracksummary_pca256`
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Former processing ID: `alphagenome_tss1mb_regulatory_tracksummary_pca256_v1_1`
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## Public files
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- `embeddings.npz`: compressed NumPy archive containing the embedding matrix under key `embeddings`.
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- `genes.tsv`: row metadata table. Row order matches the embedding matrix.
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- `metadata.json`: machine-readable provenance and processing metadata.
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- `README.md`: this per-embedding documentation file.
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## Matrix
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- Shape: `20084 genes × 256 dimensions`
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- Dtype: `float32`
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- NPZ array key: `embeddings`
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The row order is authoritative:
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```text
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embeddings.npz['embeddings'][i, :] corresponds to genes.tsv row i
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```
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## Loading example
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```python
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import numpy as np
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import pandas as pd
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with np.load('embeddings.npz') as z:
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X = z['embeddings']
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| 35 |
+
genes = pd.read_csv('genes.tsv', sep='\t')
|
| 36 |
+
assert X.shape[0] == len(genes)
|
| 37 |
+
```
|
| 38 |
+
|
| 39 |
+
## genes.tsv columns
|
| 40 |
+
|
| 41 |
+
| Column | Non-empty values | Unique values | Example values | Meaning |
|
| 42 |
+
|---|---:|---:|---|---|
|
| 43 |
+
| `embedding_row_index` | 20084 | 20084 | 0<br>1<br>2<br>3 | Zero-based row index in this embedding matrix and genes.tsv file. |
|
| 44 |
+
| `ensembl_gene_id` | 20084 | 20084 | ENSG00000000003<br>ENSG00000000005<br>ENSG00000000419<br>ENSG00000000457 | Ensembl gene identifier; main stable identifier used to align genes across embeddings. |
|
| 45 |
+
| `gene_symbol` | 20084 | 20057 | TSPAN6<br>TNMD<br>DPM1<br>SCYL3 | Gene symbol associated with the Ensembl gene ID. |
|
| 46 |
+
| `gene_type` | 20084 | 1 | protein_coding | Gene biotype, usually protein_coding. |
|
| 47 |
+
| `chromosome` | 20084 | 24 | chrX<br>chr20<br>chr1<br>chr6 | Chromosome for the gene or modeled interval. |
|
| 48 |
+
| `gene_start` | 20084 | 20026 | 100627108<br>100584936<br>50934852<br>169846981 | Gene start coordinate in the stated genome assembly. |
|
| 49 |
+
| `gene_end` | 20084 | 19975 | 100639991<br>100599885<br>50959140<br>169894267 | Gene end coordinate in the stated genome assembly. |
|
| 50 |
+
| `strand` | 20084 | 2 | -<br>+ | Genomic strand. |
|
| 51 |
+
| `assembly` | 20084 | 1 | GRCh38 | Genome assembly used for coordinates. |
|
| 52 |
+
| `tss_1based` | 20084 | 20034 | 100639991<br>100584936<br>50959140<br>169894267 | Transcription start site coordinate in 1-based coordinates. |
|
| 53 |
+
| `input_interval` | 20084 | 20050 | chrX:100115702-101164278:-<br>chrX:100060648-101109224:+<br>chr20:50434851-51483427:-<br>chr1:169369978-170418554:- | Genomic interval used as model input. |
|
| 54 |
+
|
| 55 |
+
## Basic metadata
|
| 56 |
+
|
| 57 |
+
| Field | Value |
|
| 58 |
+
|---|---|
|
| 59 |
+
| `status` | processed_qc_passed |
|
| 60 |
+
| `embedding_name` | AlphaGenome-TSS1Mb-regulatoryTrackSummary-PCA256-v1.1 |
|
| 61 |
+
|
| 62 |
+
## Detailed processing notes
|
| 63 |
+
|
| 64 |
+
TODO: manually paste and curate the processing explanation for this embedding from the central project README.
|
| 65 |
+
|
| 66 |
+
Please include, when relevant:
|
| 67 |
+
|
| 68 |
+
- original source/model/checkpoint;
|
| 69 |
+
- whether the embedding was downloaded or generated locally;
|
| 70 |
+
- input data used;
|
| 71 |
+
- identifier mapping and filtering decisions;
|
| 72 |
+
- pooling, aggregation, PCA, or normalization method;
|
| 73 |
+
- coverage and important caveats;
|
| 74 |
+
- license or redistribution notes.
|
data/embeddings/{alphagenome_tss1mb_regulatory_tracksummary_pca256_v1_1/alphagenome_tss1mb_regulatory_tracksummary_pca256_v1_1_embeddings.npz → alphagenome_tss1mb_regulatory_tracksummary_pca256/embeddings.npz}
RENAMED
|
File without changes
|
data/embeddings/{alphagenome_tss1mb_regulatory_tracksummary_pca256_v1_1/alphagenome_tss1mb_regulatory_tracksummary_pca256_v1_1_genes.tsv → alphagenome_tss1mb_regulatory_tracksummary_pca256/genes.tsv}
RENAMED
|
File without changes
|
data/embeddings/{alphagenome_tss1mb_regulatory_tracksummary_pca256_v1_1/alphagenome_tss1mb_regulatory_tracksummary_pca256_v1_1_metadata.json → alphagenome_tss1mb_regulatory_tracksummary_pca256/metadata.json}
RENAMED
|
@@ -30,5 +30,13 @@
|
|
| 30 |
"full_1mb_mean",
|
| 31 |
"central_10kb_max"
|
| 32 |
],
|
| 33 |
-
"transform": "signed log1p per summary feature, z-score across genes, PCA to 256 dimensions"
|
| 34 |
-
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 30 |
"full_1mb_mean",
|
| 31 |
"central_10kb_max"
|
| 32 |
],
|
| 33 |
+
"transform": "signed log1p per summary feature, z-score across genes, PCA to 256 dimensions",
|
| 34 |
+
"embedding_id": "alphagenome_tss1mb_regulatory_tracksummary_pca256",
|
| 35 |
+
"former_processing_embedding_id": "alphagenome_tss1mb_regulatory_tracksummary_pca256_v1_1",
|
| 36 |
+
"public_file_structure": {
|
| 37 |
+
"embeddings": "embeddings.npz",
|
| 38 |
+
"genes": "genes.tsv",
|
| 39 |
+
"metadata": "metadata.json",
|
| 40 |
+
"readme": "README.md"
|
| 41 |
+
}
|
| 42 |
+
}
|
data/embeddings/basenji2_tss_131kb_human_central3/README.md
ADDED
|
@@ -0,0 +1,77 @@
|
|
|
|
|
|
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|
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|
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|
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|
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|
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|
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|
|
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|
|
|
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|
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|
|
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|
|
|
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|
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|
|
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|
|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 1 |
+
# Basenji2-TSS-131kb-human-central3-log1p-zscore-v1.1
|
| 2 |
+
|
| 3 |
+
Embedding ID: `basenji2_tss_131kb_human_central3`
|
| 4 |
+
|
| 5 |
+
Former processing ID: `basenji2_tss_131kb_human_central3_v1_1`
|
| 6 |
+
|
| 7 |
+
## Public files
|
| 8 |
+
|
| 9 |
+
- `embeddings.npz`: compressed NumPy archive containing the embedding matrix under key `embeddings`.
|
| 10 |
+
- `genes.tsv`: row metadata table. Row order matches the embedding matrix.
|
| 11 |
+
- `metadata.json`: machine-readable provenance and processing metadata.
|
| 12 |
+
- `README.md`: this per-embedding documentation file.
|
| 13 |
+
|
| 14 |
+
## Matrix
|
| 15 |
+
|
| 16 |
+
- Shape: `20097 genes × 5313 dimensions`
|
| 17 |
+
- Dtype: `float32`
|
| 18 |
+
- NPZ array key: `embeddings`
|
| 19 |
+
|
| 20 |
+
The row order is authoritative:
|
| 21 |
+
|
| 22 |
+
```text
|
| 23 |
+
embeddings.npz['embeddings'][i, :] corresponds to genes.tsv row i
|
| 24 |
+
```
|
| 25 |
+
|
| 26 |
+
## Loading example
|
| 27 |
+
|
| 28 |
+
```python
|
| 29 |
+
import numpy as np
|
| 30 |
+
import pandas as pd
|
| 31 |
+
|
| 32 |
+
with np.load('embeddings.npz') as z:
|
| 33 |
+
X = z['embeddings']
|
| 34 |
+
|
| 35 |
+
genes = pd.read_csv('genes.tsv', sep='\t')
|
| 36 |
+
assert X.shape[0] == len(genes)
|
| 37 |
+
```
|
| 38 |
+
|
| 39 |
+
## genes.tsv columns
|
| 40 |
+
|
| 41 |
+
| Column | Non-empty values | Unique values | Example values | Meaning |
|
| 42 |
+
|---|---:|---:|---|---|
|
| 43 |
+
| `ensembl_gene_id` | 20097 | 20097 | ENSG00000000003<br>ENSG00000000005<br>ENSG00000000419<br>ENSG00000000457 | Ensembl gene identifier; main stable identifier used to align genes across embeddings. |
|
| 44 |
+
| `gene_symbol` | 20097 | 20070 | TSPAN6<br>TNMD<br>DPM1<br>SCYL3 | Gene symbol associated with the Ensembl gene ID. |
|
| 45 |
+
| `entrez_id` | 19545 | 19511 | 7105<br>64102<br>8813<br>57147 | NCBI Entrez Gene identifier, when available. |
|
| 46 |
+
| `uniprot_id` | 20045 | 19860 | O43657<br>Q9H2S6<br>O60762<br>Q8IZE3 | UniProt accession or identifier, when available. |
|
| 47 |
+
| `gene_type` | 20097 | 1 | protein_coding | Gene biotype, usually protein_coding. |
|
| 48 |
+
| `chromosome` | 20097 | 25 | chrX<br>chr20<br>chr1<br>chr6 | Chromosome for the gene or modeled interval. |
|
| 49 |
+
| `gene_start` | 20097 | 20039 | 100627108<br>100584936<br>50934852<br>169846981 | Gene start coordinate in the stated genome assembly. |
|
| 50 |
+
| `gene_end` | 20097 | 19988 | 100639991<br>100599885<br>50959140<br>169894267 | Gene end coordinate in the stated genome assembly. |
|
| 51 |
+
| `strand` | 20097 | 2 | -<br>+ | Genomic strand. |
|
| 52 |
+
| `tss_1based` | 20097 | 20047 | 100639991<br>100584936<br>50959140<br>169894267 | Transcription start site coordinate in 1-based coordinates. |
|
| 53 |
+
| `tss_0based` | 20097 | 20047 | 100639990<br>100584935<br>50959139<br>169894266 | Transcription start site coordinate in 0-based coordinates. |
|
| 54 |
+
| `assembly` | 20097 | 1 | GRCh38 | Genome assembly used for coordinates. |
|
| 55 |
+
| `gencode_release` | 20097 | 1 | 49 | GENCODE release used for annotation. |
|
| 56 |
+
|
| 57 |
+
## Basic metadata
|
| 58 |
+
|
| 59 |
+
| Field | Value |
|
| 60 |
+
|---|---|
|
| 61 |
+
| `status` | processed_qc_passed |
|
| 62 |
+
| `modality` | regulatory DNA / Basenji2 TSS sequence model |
|
| 63 |
+
| `embedding_name` | Basenji2-TSS-131kb-human-central3-log1p-zscore-v1.1 |
|
| 64 |
+
|
| 65 |
+
## Detailed processing notes
|
| 66 |
+
|
| 67 |
+
TODO: manually paste and curate the processing explanation for this embedding from the central project README.
|
| 68 |
+
|
| 69 |
+
Please include, when relevant:
|
| 70 |
+
|
| 71 |
+
- original source/model/checkpoint;
|
| 72 |
+
- whether the embedding was downloaded or generated locally;
|
| 73 |
+
- input data used;
|
| 74 |
+
- identifier mapping and filtering decisions;
|
| 75 |
+
- pooling, aggregation, PCA, or normalization method;
|
| 76 |
+
- coverage and important caveats;
|
| 77 |
+
- license or redistribution notes.
|
data/embeddings/{basenji2_tss_131kb_human_central3_v1_1/basenji2_tss_131kb_human_central3_v1_1_embeddings.npz → basenji2_tss_131kb_human_central3/embeddings.npz}
RENAMED
|
File without changes
|
data/embeddings/{basenji2_tss_131kb_human_central3_v1_1/basenji2_tss_131kb_human_central3_v1_1_genes.tsv → basenji2_tss_131kb_human_central3/genes.tsv}
RENAMED
|
File without changes
|
data/embeddings/{basenji2_tss_131kb_human_central3_v1_1/basenji2_tss_131kb_human_central3_v1_1_metadata.json → basenji2_tss_131kb_human_central3/metadata.json}
RENAMED
|
@@ -31,5 +31,13 @@
|
|
| 31 |
"n_valid_tss_windows": 20097,
|
| 32 |
"n_skipped_tss_windows": 0,
|
| 33 |
"dimension": 5313,
|
| 34 |
-
"created_at": "2026-07-10T06:17:21"
|
| 35 |
-
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 31 |
"n_valid_tss_windows": 20097,
|
| 32 |
"n_skipped_tss_windows": 0,
|
| 33 |
"dimension": 5313,
|
| 34 |
+
"created_at": "2026-07-10T06:17:21",
|
| 35 |
+
"embedding_id": "basenji2_tss_131kb_human_central3",
|
| 36 |
+
"former_processing_embedding_id": "basenji2_tss_131kb_human_central3_v1_1",
|
| 37 |
+
"public_file_structure": {
|
| 38 |
+
"embeddings": "embeddings.npz",
|
| 39 |
+
"genes": "genes.tsv",
|
| 40 |
+
"metadata": "metadata.json",
|
| 41 |
+
"readme": "README.md"
|
| 42 |
+
}
|
| 43 |
+
}
|
data/embeddings/biobert_gene_protein_summary/README.md
ADDED
|
@@ -0,0 +1,75 @@
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 1 |
+
# BioBERT-GeneProteinSummary-v1.1
|
| 2 |
+
|
| 3 |
+
Embedding ID: `biobert_gene_protein_summary`
|
| 4 |
+
|
| 5 |
+
Former processing ID: `biobert_gene_protein_summary_v1_1`
|
| 6 |
+
|
| 7 |
+
## Public files
|
| 8 |
+
|
| 9 |
+
- `embeddings.npz`: compressed NumPy archive containing the embedding matrix under key `embeddings`.
|
| 10 |
+
- `genes.tsv`: row metadata table. Row order matches the embedding matrix.
|
| 11 |
+
- `metadata.json`: machine-readable provenance and processing metadata.
|
| 12 |
+
- `README.md`: this per-embedding documentation file.
|
| 13 |
+
|
| 14 |
+
## Matrix
|
| 15 |
+
|
| 16 |
+
- Shape: `19168 genes × 768 dimensions`
|
| 17 |
+
- Dtype: `float32`
|
| 18 |
+
- NPZ array key: `embeddings`
|
| 19 |
+
|
| 20 |
+
The row order is authoritative:
|
| 21 |
+
|
| 22 |
+
```text
|
| 23 |
+
embeddings.npz['embeddings'][i, :] corresponds to genes.tsv row i
|
| 24 |
+
```
|
| 25 |
+
|
| 26 |
+
## Loading example
|
| 27 |
+
|
| 28 |
+
```python
|
| 29 |
+
import numpy as np
|
| 30 |
+
import pandas as pd
|
| 31 |
+
|
| 32 |
+
with np.load('embeddings.npz') as z:
|
| 33 |
+
X = z['embeddings']
|
| 34 |
+
|
| 35 |
+
genes = pd.read_csv('genes.tsv', sep='\t')
|
| 36 |
+
assert X.shape[0] == len(genes)
|
| 37 |
+
```
|
| 38 |
+
|
| 39 |
+
## genes.tsv columns
|
| 40 |
+
|
| 41 |
+
| Column | Non-empty values | Unique values | Example values | Meaning |
|
| 42 |
+
|---|---:|---:|---|---|
|
| 43 |
+
| `row_index` | 19168 | 19168 | 0<br>1<br>2<br>3 | Zero-based row index in this embedding matrix and genes.tsv file. |
|
| 44 |
+
| `ensembl_gene_id` | 19168 | 19168 | ENSG00000000003<br>ENSG00000000005<br>ENSG00000000419<br>ENSG00000000457 | Ensembl gene identifier; main stable identifier used to align genes across embeddings. |
|
| 45 |
+
| `gene_symbol` | 19168 | 19143 | TSPAN6<br>TNMD<br>DPM1<br>SCYL3 | Gene symbol associated with the Ensembl gene ID. |
|
| 46 |
+
| `hgnc_approved_symbol` | 19082 | 19083 | TSPAN6<br>TNMD<br>DPM1<br>SCYL3 | HGNC-approved gene symbol from the master table. |
|
| 47 |
+
| `entrez_id` | 19118 | 19092 | 7105<br>64102<br>8813<br>57147 | NCBI Entrez Gene identifier, when available. |
|
| 48 |
+
| `uniprot_id` | 19153 | 18980 | O43657<br>Q9H2S6<br>O60762<br>Q8IZE3 | UniProt accession or identifier, when available. |
|
| 49 |
+
| `summary_key` | 19168 | 19082 | TSPAN6<br>TNMD<br>DPM1<br>SCYL3 | Identifier used to retrieve the gene/protein text summary. |
|
| 50 |
+
| `summary_mapping_source` | 19168 | 3 | gene_symbol<br>map_symbols_all_fallback<br>hgnc_approved_symbol | Mapping route used to select the gene/protein text summary. |
|
| 51 |
+
|
| 52 |
+
## Basic metadata
|
| 53 |
+
|
| 54 |
+
| Field | Value |
|
| 55 |
+
|---|---|
|
| 56 |
+
| `modality` | literature_text_gene_summary |
|
| 57 |
+
| `embedding_name` | BioBERT-GeneProteinSummary-v1.1 |
|
| 58 |
+
| `download_source` | GenePT Zenodo v2 summaries |
|
| 59 |
+
| `embedding_generated_by` | Daniel locally |
|
| 60 |
+
| `model_checkpoint` | dmis-lab/biobert-base-cased-v1.2 |
|
| 61 |
+
| `pooling_strategy` | final hidden layer mean pooling over valid non-special, non-padding tokens |
|
| 62 |
+
|
| 63 |
+
## Detailed processing notes
|
| 64 |
+
|
| 65 |
+
TODO: manually paste and curate the processing explanation for this embedding from the central project README.
|
| 66 |
+
|
| 67 |
+
Please include, when relevant:
|
| 68 |
+
|
| 69 |
+
- original source/model/checkpoint;
|
| 70 |
+
- whether the embedding was downloaded or generated locally;
|
| 71 |
+
- input data used;
|
| 72 |
+
- identifier mapping and filtering decisions;
|
| 73 |
+
- pooling, aggregation, PCA, or normalization method;
|
| 74 |
+
- coverage and important caveats;
|
| 75 |
+
- license or redistribution notes.
|
data/embeddings/{biobert_gene_protein_summary_v1_1/biobert_gene_protein_summary_v1_1_embeddings.npz → biobert_gene_protein_summary/embeddings.npz}
RENAMED
|
File without changes
|
data/embeddings/{biobert_gene_protein_summary_v1_1/biobert_gene_protein_summary_v1_1_genes.tsv → biobert_gene_protein_summary/genes.tsv}
RENAMED
|
File without changes
|
data/embeddings/{biobert_gene_protein_summary_v1_1/biobert_gene_protein_summary_v1_1_metadata.json → biobert_gene_protein_summary/metadata.json}
RENAMED
|
@@ -23,5 +23,13 @@
|
|
| 23 |
"zero_vectors": 0,
|
| 24 |
"nan_count": 0,
|
| 25 |
"inf_count": 0,
|
| 26 |
-
"runtime_minutes": 3.477354129155477
|
| 27 |
-
|
|
|
|
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|
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|
|
|
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|
|
| 23 |
"zero_vectors": 0,
|
| 24 |
"nan_count": 0,
|
| 25 |
"inf_count": 0,
|
| 26 |
+
"runtime_minutes": 3.477354129155477,
|
| 27 |
+
"embedding_id": "biobert_gene_protein_summary",
|
| 28 |
+
"former_processing_embedding_id": "biobert_gene_protein_summary_v1_1",
|
| 29 |
+
"public_file_structure": {
|
| 30 |
+
"embeddings": "embeddings.npz",
|
| 31 |
+
"genes": "genes.tsv",
|
| 32 |
+
"metadata": "metadata.json",
|
| 33 |
+
"readme": "README.md"
|
| 34 |
+
}
|
| 35 |
+
}
|
data/embeddings/bioconceptvec_cbow/README.md
ADDED
|
@@ -0,0 +1,75 @@
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|
| 1 |
+
# BioConceptVec-CBOW-v1.1
|
| 2 |
+
|
| 3 |
+
Embedding ID: `bioconceptvec_cbow`
|
| 4 |
+
|
| 5 |
+
Former processing ID: `bioconceptvec_cbow_v1_1`
|
| 6 |
+
|
| 7 |
+
## Public files
|
| 8 |
+
|
| 9 |
+
- `embeddings.npz`: compressed NumPy archive containing the embedding matrix under key `embeddings`.
|
| 10 |
+
- `genes.tsv`: row metadata table. Row order matches the embedding matrix.
|
| 11 |
+
- `metadata.json`: machine-readable provenance and processing metadata.
|
| 12 |
+
- `README.md`: this per-embedding documentation file.
|
| 13 |
+
|
| 14 |
+
## Matrix
|
| 15 |
+
|
| 16 |
+
- Shape: `17040 genes × 100 dimensions`
|
| 17 |
+
- Dtype: `float32`
|
| 18 |
+
- NPZ array key: `embeddings`
|
| 19 |
+
|
| 20 |
+
The row order is authoritative:
|
| 21 |
+
|
| 22 |
+
```text
|
| 23 |
+
embeddings.npz['embeddings'][i, :] corresponds to genes.tsv row i
|
| 24 |
+
```
|
| 25 |
+
|
| 26 |
+
## Loading example
|
| 27 |
+
|
| 28 |
+
```python
|
| 29 |
+
import numpy as np
|
| 30 |
+
import pandas as pd
|
| 31 |
+
|
| 32 |
+
with np.load('embeddings.npz') as z:
|
| 33 |
+
X = z['embeddings']
|
| 34 |
+
|
| 35 |
+
genes = pd.read_csv('genes.tsv', sep='\t')
|
| 36 |
+
assert X.shape[0] == len(genes)
|
| 37 |
+
```
|
| 38 |
+
|
| 39 |
+
## genes.tsv columns
|
| 40 |
+
|
| 41 |
+
| Column | Non-empty values | Unique values | Example values | Meaning |
|
| 42 |
+
|---|---:|---:|---|---|
|
| 43 |
+
| `ensembl_gene_id` | 17040 | 17040 | ENSG00000000003<br>ENSG00000000005<br>ENSG00000000419<br>ENSG00000000457 | Ensembl gene identifier; main stable identifier used to align genes across embeddings. |
|
| 44 |
+
| `gene_symbol` | 17040 | 17040 | TSPAN6<br>TNMD<br>DPM1<br>SCYL3 | Gene symbol associated with the Ensembl gene ID. |
|
| 45 |
+
| `gene_type` | 17040 | 1 | protein_coding | Gene biotype, usually protein_coding. |
|
| 46 |
+
| `entrez_id` | 17040 | 17040 | 7105<br>64102<br>8813<br>57147 | NCBI Entrez Gene identifier, when available. |
|
| 47 |
+
| `uniprot_id` | 17039 | 16973 | O43657<br>Q9H2S6<br>O60762<br>Q8IZE3 | UniProt accession or identifier, when available. |
|
| 48 |
+
| `canonical_transcript_id` | 17040 | 17040 | ENST00000373020<br>ENST00000373031<br>ENST00000371588<br>ENST00000367771 | Canonical transcript identifier recorded or used for this gene. |
|
| 49 |
+
| `canonical_protein_id` | 17040 | 17040 | ENSP00000362111<br>ENSP00000362122<br>ENSP00000360644<br>ENSP00000356745 | Canonical protein identifier recorded or used for this gene. |
|
| 50 |
+
| `source_embedding` | 17040 | 1 | BioConceptVec-CBOW-v1.1 | Name of the original source embedding. |
|
| 51 |
+
| `source_identifier_type` | 17040 | 1 | entrez_id | Type of source identifier used by the original embedding. |
|
| 52 |
+
| `source_key_count` | 17040 | 2 | 1<br>2 | Number of source keys mapped or collapsed to this final gene. |
|
| 53 |
+
| `source_keys_examples` | 17040 | 17040 | Gene_7105<br>Gene_64102<br>Gene_8813<br>Gene_57147 | Example source keys mapped to this final gene. |
|
| 54 |
+
| `mapping_methods` | 17040 | 1 | entrez_id_from_map_entrez_ids_all | Mapping methods used to connect source records to the master gene table. |
|
| 55 |
+
|
| 56 |
+
## Basic metadata
|
| 57 |
+
|
| 58 |
+
| Field | Value |
|
| 59 |
+
|---|---|
|
| 60 |
+
| `modality` | biomedical_literature_text |
|
| 61 |
+
| `embedding_name` | BioConceptVec-CBOW-v1.1 |
|
| 62 |
+
|
| 63 |
+
## Detailed processing notes
|
| 64 |
+
|
| 65 |
+
TODO: manually paste and curate the processing explanation for this embedding from the central project README.
|
| 66 |
+
|
| 67 |
+
Please include, when relevant:
|
| 68 |
+
|
| 69 |
+
- original source/model/checkpoint;
|
| 70 |
+
- whether the embedding was downloaded or generated locally;
|
| 71 |
+
- input data used;
|
| 72 |
+
- identifier mapping and filtering decisions;
|
| 73 |
+
- pooling, aggregation, PCA, or normalization method;
|
| 74 |
+
- coverage and important caveats;
|
| 75 |
+
- license or redistribution notes.
|
data/embeddings/{bioconceptvec_cbow_v1_1/bioconceptvec_cbow_v1_1_embeddings.npz → bioconceptvec_cbow/embeddings.npz}
RENAMED
|
File without changes
|
data/embeddings/{bioconceptvec_cbow_v1_1/bioconceptvec_cbow_v1_1_genes.tsv → bioconceptvec_cbow/genes.tsv}
RENAMED
|
File without changes
|
data/embeddings/{bioconceptvec_cbow_v1_1/bioconceptvec_cbow_v1_1_metadata.json → bioconceptvec_cbow/metadata.json}
RENAMED
|
@@ -27,5 +27,13 @@
|
|
| 27 |
"coverage_of_master_rows": 0.8478877444394686,
|
| 28 |
"n_zero_vectors": 0,
|
| 29 |
"output_npz": "/local/home/dtabares/data/processed_embeddings/bioconceptvec_cbow_v1_1/bioconceptvec_cbow_v1_1_embeddings.npz",
|
| 30 |
-
"output_genes_tsv": "/local/home/dtabares/data/processed_embeddings/bioconceptvec_cbow_v1_1/bioconceptvec_cbow_v1_1_genes.tsv"
|
| 31 |
-
|
|
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|
|
|
|
| 27 |
"coverage_of_master_rows": 0.8478877444394686,
|
| 28 |
"n_zero_vectors": 0,
|
| 29 |
"output_npz": "/local/home/dtabares/data/processed_embeddings/bioconceptvec_cbow_v1_1/bioconceptvec_cbow_v1_1_embeddings.npz",
|
| 30 |
+
"output_genes_tsv": "/local/home/dtabares/data/processed_embeddings/bioconceptvec_cbow_v1_1/bioconceptvec_cbow_v1_1_genes.tsv",
|
| 31 |
+
"embedding_id": "bioconceptvec_cbow",
|
| 32 |
+
"former_processing_embedding_id": "bioconceptvec_cbow_v1_1",
|
| 33 |
+
"public_file_structure": {
|
| 34 |
+
"embeddings": "embeddings.npz",
|
| 35 |
+
"genes": "genes.tsv",
|
| 36 |
+
"metadata": "metadata.json",
|
| 37 |
+
"readme": "README.md"
|
| 38 |
+
}
|
| 39 |
+
}
|
data/embeddings/bioconceptvec_fasttext/README.md
ADDED
|
@@ -0,0 +1,75 @@
|
|
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|
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|
|
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|
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|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 1 |
+
# BioConceptVec-fastText-v1.1
|
| 2 |
+
|
| 3 |
+
Embedding ID: `bioconceptvec_fasttext`
|
| 4 |
+
|
| 5 |
+
Former processing ID: `bioconceptvec_fasttext_v1_1`
|
| 6 |
+
|
| 7 |
+
## Public files
|
| 8 |
+
|
| 9 |
+
- `embeddings.npz`: compressed NumPy archive containing the embedding matrix under key `embeddings`.
|
| 10 |
+
- `genes.tsv`: row metadata table. Row order matches the embedding matrix.
|
| 11 |
+
- `metadata.json`: machine-readable provenance and processing metadata.
|
| 12 |
+
- `README.md`: this per-embedding documentation file.
|
| 13 |
+
|
| 14 |
+
## Matrix
|
| 15 |
+
|
| 16 |
+
- Shape: `17040 genes × 100 dimensions`
|
| 17 |
+
- Dtype: `float32`
|
| 18 |
+
- NPZ array key: `embeddings`
|
| 19 |
+
|
| 20 |
+
The row order is authoritative:
|
| 21 |
+
|
| 22 |
+
```text
|
| 23 |
+
embeddings.npz['embeddings'][i, :] corresponds to genes.tsv row i
|
| 24 |
+
```
|
| 25 |
+
|
| 26 |
+
## Loading example
|
| 27 |
+
|
| 28 |
+
```python
|
| 29 |
+
import numpy as np
|
| 30 |
+
import pandas as pd
|
| 31 |
+
|
| 32 |
+
with np.load('embeddings.npz') as z:
|
| 33 |
+
X = z['embeddings']
|
| 34 |
+
|
| 35 |
+
genes = pd.read_csv('genes.tsv', sep='\t')
|
| 36 |
+
assert X.shape[0] == len(genes)
|
| 37 |
+
```
|
| 38 |
+
|
| 39 |
+
## genes.tsv columns
|
| 40 |
+
|
| 41 |
+
| Column | Non-empty values | Unique values | Example values | Meaning |
|
| 42 |
+
|---|---:|---:|---|---|
|
| 43 |
+
| `ensembl_gene_id` | 17040 | 17040 | ENSG00000000003<br>ENSG00000000005<br>ENSG00000000419<br>ENSG00000000457 | Ensembl gene identifier; main stable identifier used to align genes across embeddings. |
|
| 44 |
+
| `gene_symbol` | 17040 | 17040 | TSPAN6<br>TNMD<br>DPM1<br>SCYL3 | Gene symbol associated with the Ensembl gene ID. |
|
| 45 |
+
| `gene_type` | 17040 | 1 | protein_coding | Gene biotype, usually protein_coding. |
|
| 46 |
+
| `entrez_id` | 17040 | 17040 | 7105<br>64102<br>8813<br>57147 | NCBI Entrez Gene identifier, when available. |
|
| 47 |
+
| `uniprot_id` | 17039 | 16973 | O43657<br>Q9H2S6<br>O60762<br>Q8IZE3 | UniProt accession or identifier, when available. |
|
| 48 |
+
| `canonical_transcript_id` | 17040 | 17040 | ENST00000373020<br>ENST00000373031<br>ENST00000371588<br>ENST00000367771 | Canonical transcript identifier recorded or used for this gene. |
|
| 49 |
+
| `canonical_protein_id` | 17040 | 17040 | ENSP00000362111<br>ENSP00000362122<br>ENSP00000360644<br>ENSP00000356745 | Canonical protein identifier recorded or used for this gene. |
|
| 50 |
+
| `source_embedding` | 17040 | 1 | BioConceptVec-fastText-v1.1 | Name of the original source embedding. |
|
| 51 |
+
| `source_identifier_type` | 17040 | 1 | entrez_id | Type of source identifier used by the original embedding. |
|
| 52 |
+
| `source_key_count` | 17040 | 2 | 1<br>2 | Number of source keys mapped or collapsed to this final gene. |
|
| 53 |
+
| `source_keys_examples` | 17040 | 17040 | Gene_7105<br>Gene_64102<br>Gene_8813<br>Gene_57147 | Example source keys mapped to this final gene. |
|
| 54 |
+
| `mapping_methods` | 17040 | 1 | entrez_id_from_map_entrez_ids_all | Mapping methods used to connect source records to the master gene table. |
|
| 55 |
+
|
| 56 |
+
## Basic metadata
|
| 57 |
+
|
| 58 |
+
| Field | Value |
|
| 59 |
+
|---|---|
|
| 60 |
+
| `modality` | biomedical_literature_text |
|
| 61 |
+
| `embedding_name` | BioConceptVec-fastText-v1.1 |
|
| 62 |
+
|
| 63 |
+
## Detailed processing notes
|
| 64 |
+
|
| 65 |
+
TODO: manually paste and curate the processing explanation for this embedding from the central project README.
|
| 66 |
+
|
| 67 |
+
Please include, when relevant:
|
| 68 |
+
|
| 69 |
+
- original source/model/checkpoint;
|
| 70 |
+
- whether the embedding was downloaded or generated locally;
|
| 71 |
+
- input data used;
|
| 72 |
+
- identifier mapping and filtering decisions;
|
| 73 |
+
- pooling, aggregation, PCA, or normalization method;
|
| 74 |
+
- coverage and important caveats;
|
| 75 |
+
- license or redistribution notes.
|
data/embeddings/{bioconceptvec_fasttext_v1_1/bioconceptvec_fasttext_v1_1_embeddings.npz → bioconceptvec_fasttext/embeddings.npz}
RENAMED
|
File without changes
|
data/embeddings/{bioconceptvec_fasttext_v1_1/bioconceptvec_fasttext_v1_1_genes.tsv → bioconceptvec_fasttext/genes.tsv}
RENAMED
|
File without changes
|
data/embeddings/{bioconceptvec_fasttext_v1_1/bioconceptvec_fasttext_v1_1_metadata.json → bioconceptvec_fasttext/metadata.json}
RENAMED
|
@@ -27,5 +27,13 @@
|
|
| 27 |
"coverage_of_master_rows": 0.8478877444394686,
|
| 28 |
"n_zero_vectors": 0,
|
| 29 |
"output_npz": "/local/home/dtabares/data/processed_embeddings/bioconceptvec_fasttext_v1_1/bioconceptvec_fasttext_v1_1_embeddings.npz",
|
| 30 |
-
"output_genes_tsv": "/local/home/dtabares/data/processed_embeddings/bioconceptvec_fasttext_v1_1/bioconceptvec_fasttext_v1_1_genes.tsv"
|
| 31 |
-
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 27 |
"coverage_of_master_rows": 0.8478877444394686,
|
| 28 |
"n_zero_vectors": 0,
|
| 29 |
"output_npz": "/local/home/dtabares/data/processed_embeddings/bioconceptvec_fasttext_v1_1/bioconceptvec_fasttext_v1_1_embeddings.npz",
|
| 30 |
+
"output_genes_tsv": "/local/home/dtabares/data/processed_embeddings/bioconceptvec_fasttext_v1_1/bioconceptvec_fasttext_v1_1_genes.tsv",
|
| 31 |
+
"embedding_id": "bioconceptvec_fasttext",
|
| 32 |
+
"former_processing_embedding_id": "bioconceptvec_fasttext_v1_1",
|
| 33 |
+
"public_file_structure": {
|
| 34 |
+
"embeddings": "embeddings.npz",
|
| 35 |
+
"genes": "genes.tsv",
|
| 36 |
+
"metadata": "metadata.json",
|
| 37 |
+
"readme": "README.md"
|
| 38 |
+
}
|
| 39 |
+
}
|
data/embeddings/bioconceptvec_glove/README.md
ADDED
|
@@ -0,0 +1,75 @@
|
|
|
|
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|
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|
|
|
| 1 |
+
# BioConceptVec-GloVe-v1.1
|
| 2 |
+
|
| 3 |
+
Embedding ID: `bioconceptvec_glove`
|
| 4 |
+
|
| 5 |
+
Former processing ID: `bioconceptvec_glove_v1_1`
|
| 6 |
+
|
| 7 |
+
## Public files
|
| 8 |
+
|
| 9 |
+
- `embeddings.npz`: compressed NumPy archive containing the embedding matrix under key `embeddings`.
|
| 10 |
+
- `genes.tsv`: row metadata table. Row order matches the embedding matrix.
|
| 11 |
+
- `metadata.json`: machine-readable provenance and processing metadata.
|
| 12 |
+
- `README.md`: this per-embedding documentation file.
|
| 13 |
+
|
| 14 |
+
## Matrix
|
| 15 |
+
|
| 16 |
+
- Shape: `17040 genes × 100 dimensions`
|
| 17 |
+
- Dtype: `float32`
|
| 18 |
+
- NPZ array key: `embeddings`
|
| 19 |
+
|
| 20 |
+
The row order is authoritative:
|
| 21 |
+
|
| 22 |
+
```text
|
| 23 |
+
embeddings.npz['embeddings'][i, :] corresponds to genes.tsv row i
|
| 24 |
+
```
|
| 25 |
+
|
| 26 |
+
## Loading example
|
| 27 |
+
|
| 28 |
+
```python
|
| 29 |
+
import numpy as np
|
| 30 |
+
import pandas as pd
|
| 31 |
+
|
| 32 |
+
with np.load('embeddings.npz') as z:
|
| 33 |
+
X = z['embeddings']
|
| 34 |
+
|
| 35 |
+
genes = pd.read_csv('genes.tsv', sep='\t')
|
| 36 |
+
assert X.shape[0] == len(genes)
|
| 37 |
+
```
|
| 38 |
+
|
| 39 |
+
## genes.tsv columns
|
| 40 |
+
|
| 41 |
+
| Column | Non-empty values | Unique values | Example values | Meaning |
|
| 42 |
+
|---|---:|---:|---|---|
|
| 43 |
+
| `ensembl_gene_id` | 17040 | 17040 | ENSG00000000003<br>ENSG00000000005<br>ENSG00000000419<br>ENSG00000000457 | Ensembl gene identifier; main stable identifier used to align genes across embeddings. |
|
| 44 |
+
| `gene_symbol` | 17040 | 17040 | TSPAN6<br>TNMD<br>DPM1<br>SCYL3 | Gene symbol associated with the Ensembl gene ID. |
|
| 45 |
+
| `gene_type` | 17040 | 1 | protein_coding | Gene biotype, usually protein_coding. |
|
| 46 |
+
| `entrez_id` | 17040 | 17040 | 7105<br>64102<br>8813<br>57147 | NCBI Entrez Gene identifier, when available. |
|
| 47 |
+
| `uniprot_id` | 17039 | 16973 | O43657<br>Q9H2S6<br>O60762<br>Q8IZE3 | UniProt accession or identifier, when available. |
|
| 48 |
+
| `canonical_transcript_id` | 17040 | 17040 | ENST00000373020<br>ENST00000373031<br>ENST00000371588<br>ENST00000367771 | Canonical transcript identifier recorded or used for this gene. |
|
| 49 |
+
| `canonical_protein_id` | 17040 | 17040 | ENSP00000362111<br>ENSP00000362122<br>ENSP00000360644<br>ENSP00000356745 | Canonical protein identifier recorded or used for this gene. |
|
| 50 |
+
| `source_embedding` | 17040 | 1 | BioConceptVec-GloVe-v1.1 | Name of the original source embedding. |
|
| 51 |
+
| `source_identifier_type` | 17040 | 1 | entrez_id | Type of source identifier used by the original embedding. |
|
| 52 |
+
| `source_key_count` | 17040 | 2 | 1<br>2 | Number of source keys mapped or collapsed to this final gene. |
|
| 53 |
+
| `source_keys_examples` | 17040 | 17040 | Gene_7105<br>Gene_64102<br>Gene_8813<br>Gene_57147 | Example source keys mapped to this final gene. |
|
| 54 |
+
| `mapping_methods` | 17040 | 1 | entrez_id_from_map_entrez_ids_all | Mapping methods used to connect source records to the master gene table. |
|
| 55 |
+
|
| 56 |
+
## Basic metadata
|
| 57 |
+
|
| 58 |
+
| Field | Value |
|
| 59 |
+
|---|---|
|
| 60 |
+
| `modality` | biomedical_literature_text |
|
| 61 |
+
| `embedding_name` | BioConceptVec-GloVe-v1.1 |
|
| 62 |
+
|
| 63 |
+
## Detailed processing notes
|
| 64 |
+
|
| 65 |
+
TODO: manually paste and curate the processing explanation for this embedding from the central project README.
|
| 66 |
+
|
| 67 |
+
Please include, when relevant:
|
| 68 |
+
|
| 69 |
+
- original source/model/checkpoint;
|
| 70 |
+
- whether the embedding was downloaded or generated locally;
|
| 71 |
+
- input data used;
|
| 72 |
+
- identifier mapping and filtering decisions;
|
| 73 |
+
- pooling, aggregation, PCA, or normalization method;
|
| 74 |
+
- coverage and important caveats;
|
| 75 |
+
- license or redistribution notes.
|
data/embeddings/{bioconceptvec_glove_v1_1/bioconceptvec_glove_v1_1_embeddings.npz → bioconceptvec_glove/embeddings.npz}
RENAMED
|
File without changes
|
data/embeddings/{bioconceptvec_glove_v1_1/bioconceptvec_glove_v1_1_genes.tsv → bioconceptvec_glove/genes.tsv}
RENAMED
|
File without changes
|
data/embeddings/{bioconceptvec_glove_v1_1/bioconceptvec_glove_v1_1_metadata.json → bioconceptvec_glove/metadata.json}
RENAMED
|
@@ -27,5 +27,13 @@
|
|
| 27 |
"coverage_of_master_rows": 0.8478877444394686,
|
| 28 |
"n_zero_vectors": 0,
|
| 29 |
"output_npz": "/local/home/dtabares/data/processed_embeddings/bioconceptvec_glove_v1_1/bioconceptvec_glove_v1_1_embeddings.npz",
|
| 30 |
-
"output_genes_tsv": "/local/home/dtabares/data/processed_embeddings/bioconceptvec_glove_v1_1/bioconceptvec_glove_v1_1_genes.tsv"
|
| 31 |
-
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 27 |
"coverage_of_master_rows": 0.8478877444394686,
|
| 28 |
"n_zero_vectors": 0,
|
| 29 |
"output_npz": "/local/home/dtabares/data/processed_embeddings/bioconceptvec_glove_v1_1/bioconceptvec_glove_v1_1_embeddings.npz",
|
| 30 |
+
"output_genes_tsv": "/local/home/dtabares/data/processed_embeddings/bioconceptvec_glove_v1_1/bioconceptvec_glove_v1_1_genes.tsv",
|
| 31 |
+
"embedding_id": "bioconceptvec_glove",
|
| 32 |
+
"former_processing_embedding_id": "bioconceptvec_glove_v1_1",
|
| 33 |
+
"public_file_structure": {
|
| 34 |
+
"embeddings": "embeddings.npz",
|
| 35 |
+
"genes": "genes.tsv",
|
| 36 |
+
"metadata": "metadata.json",
|
| 37 |
+
"readme": "README.md"
|
| 38 |
+
}
|
| 39 |
+
}
|
data/embeddings/bioconceptvec_skipgram/README.md
ADDED
|
@@ -0,0 +1,75 @@
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|
|
|
|
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|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 1 |
+
# BioConceptVec-SkipGram-v1.1
|
| 2 |
+
|
| 3 |
+
Embedding ID: `bioconceptvec_skipgram`
|
| 4 |
+
|
| 5 |
+
Former processing ID: `bioconceptvec_skipgram_v1_1`
|
| 6 |
+
|
| 7 |
+
## Public files
|
| 8 |
+
|
| 9 |
+
- `embeddings.npz`: compressed NumPy archive containing the embedding matrix under key `embeddings`.
|
| 10 |
+
- `genes.tsv`: row metadata table. Row order matches the embedding matrix.
|
| 11 |
+
- `metadata.json`: machine-readable provenance and processing metadata.
|
| 12 |
+
- `README.md`: this per-embedding documentation file.
|
| 13 |
+
|
| 14 |
+
## Matrix
|
| 15 |
+
|
| 16 |
+
- Shape: `17040 genes × 100 dimensions`
|
| 17 |
+
- Dtype: `float32`
|
| 18 |
+
- NPZ array key: `embeddings`
|
| 19 |
+
|
| 20 |
+
The row order is authoritative:
|
| 21 |
+
|
| 22 |
+
```text
|
| 23 |
+
embeddings.npz['embeddings'][i, :] corresponds to genes.tsv row i
|
| 24 |
+
```
|
| 25 |
+
|
| 26 |
+
## Loading example
|
| 27 |
+
|
| 28 |
+
```python
|
| 29 |
+
import numpy as np
|
| 30 |
+
import pandas as pd
|
| 31 |
+
|
| 32 |
+
with np.load('embeddings.npz') as z:
|
| 33 |
+
X = z['embeddings']
|
| 34 |
+
|
| 35 |
+
genes = pd.read_csv('genes.tsv', sep='\t')
|
| 36 |
+
assert X.shape[0] == len(genes)
|
| 37 |
+
```
|
| 38 |
+
|
| 39 |
+
## genes.tsv columns
|
| 40 |
+
|
| 41 |
+
| Column | Non-empty values | Unique values | Example values | Meaning |
|
| 42 |
+
|---|---:|---:|---|---|
|
| 43 |
+
| `ensembl_gene_id` | 17040 | 17040 | ENSG00000000003<br>ENSG00000000005<br>ENSG00000000419<br>ENSG00000000457 | Ensembl gene identifier; main stable identifier used to align genes across embeddings. |
|
| 44 |
+
| `gene_symbol` | 17040 | 17040 | TSPAN6<br>TNMD<br>DPM1<br>SCYL3 | Gene symbol associated with the Ensembl gene ID. |
|
| 45 |
+
| `gene_type` | 17040 | 1 | protein_coding | Gene biotype, usually protein_coding. |
|
| 46 |
+
| `entrez_id` | 17040 | 17040 | 7105<br>64102<br>8813<br>57147 | NCBI Entrez Gene identifier, when available. |
|
| 47 |
+
| `uniprot_id` | 17039 | 16973 | O43657<br>Q9H2S6<br>O60762<br>Q8IZE3 | UniProt accession or identifier, when available. |
|
| 48 |
+
| `canonical_transcript_id` | 17040 | 17040 | ENST00000373020<br>ENST00000373031<br>ENST00000371588<br>ENST00000367771 | Canonical transcript identifier recorded or used for this gene. |
|
| 49 |
+
| `canonical_protein_id` | 17040 | 17040 | ENSP00000362111<br>ENSP00000362122<br>ENSP00000360644<br>ENSP00000356745 | Canonical protein identifier recorded or used for this gene. |
|
| 50 |
+
| `source_embedding` | 17040 | 1 | BioConceptVec-SkipGram-v1.1 | Name of the original source embedding. |
|
| 51 |
+
| `source_identifier_type` | 17040 | 1 | entrez_id | Type of source identifier used by the original embedding. |
|
| 52 |
+
| `source_key_count` | 17040 | 2 | 1<br>2 | Number of source keys mapped or collapsed to this final gene. |
|
| 53 |
+
| `source_keys_examples` | 17040 | 17040 | Gene_7105<br>Gene_64102<br>Gene_8813<br>Gene_57147 | Example source keys mapped to this final gene. |
|
| 54 |
+
| `mapping_methods` | 17040 | 1 | entrez_id_from_map_entrez_ids_all | Mapping methods used to connect source records to the master gene table. |
|
| 55 |
+
|
| 56 |
+
## Basic metadata
|
| 57 |
+
|
| 58 |
+
| Field | Value |
|
| 59 |
+
|---|---|
|
| 60 |
+
| `modality` | biomedical_literature_text |
|
| 61 |
+
| `embedding_name` | BioConceptVec-SkipGram-v1.1 |
|
| 62 |
+
|
| 63 |
+
## Detailed processing notes
|
| 64 |
+
|
| 65 |
+
TODO: manually paste and curate the processing explanation for this embedding from the central project README.
|
| 66 |
+
|
| 67 |
+
Please include, when relevant:
|
| 68 |
+
|
| 69 |
+
- original source/model/checkpoint;
|
| 70 |
+
- whether the embedding was downloaded or generated locally;
|
| 71 |
+
- input data used;
|
| 72 |
+
- identifier mapping and filtering decisions;
|
| 73 |
+
- pooling, aggregation, PCA, or normalization method;
|
| 74 |
+
- coverage and important caveats;
|
| 75 |
+
- license or redistribution notes.
|
data/embeddings/{bioconceptvec_skipgram_v1_1/bioconceptvec_skipgram_v1_1_embeddings.npz → bioconceptvec_skipgram/embeddings.npz}
RENAMED
|
File without changes
|
data/embeddings/{bioconceptvec_skipgram_v1_1/bioconceptvec_skipgram_v1_1_genes.tsv → bioconceptvec_skipgram/genes.tsv}
RENAMED
|
File without changes
|
data/embeddings/{bioconceptvec_skipgram_v1_1/bioconceptvec_skipgram_v1_1_metadata.json → bioconceptvec_skipgram/metadata.json}
RENAMED
|
@@ -27,5 +27,13 @@
|
|
| 27 |
"coverage_of_master_rows": 0.8478877444394686,
|
| 28 |
"n_zero_vectors": 0,
|
| 29 |
"output_npz": "/local/home/dtabares/data/processed_embeddings/bioconceptvec_skipgram_v1_1/bioconceptvec_skipgram_v1_1_embeddings.npz",
|
| 30 |
-
"output_genes_tsv": "/local/home/dtabares/data/processed_embeddings/bioconceptvec_skipgram_v1_1/bioconceptvec_skipgram_v1_1_genes.tsv"
|
| 31 |
-
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 27 |
"coverage_of_master_rows": 0.8478877444394686,
|
| 28 |
"n_zero_vectors": 0,
|
| 29 |
"output_npz": "/local/home/dtabares/data/processed_embeddings/bioconceptvec_skipgram_v1_1/bioconceptvec_skipgram_v1_1_embeddings.npz",
|
| 30 |
+
"output_genes_tsv": "/local/home/dtabares/data/processed_embeddings/bioconceptvec_skipgram_v1_1/bioconceptvec_skipgram_v1_1_genes.tsv",
|
| 31 |
+
"embedding_id": "bioconceptvec_skipgram",
|
| 32 |
+
"former_processing_embedding_id": "bioconceptvec_skipgram_v1_1",
|
| 33 |
+
"public_file_structure": {
|
| 34 |
+
"embeddings": "embeddings.npz",
|
| 35 |
+
"genes": "genes.tsv",
|
| 36 |
+
"metadata": "metadata.json",
|
| 37 |
+
"readme": "README.md"
|
| 38 |
+
}
|
| 39 |
+
}
|
data/embeddings/cmap_gse106127_cgs_mean_landmark978_zscore/README.md
ADDED
|
@@ -0,0 +1,73 @@
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
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|
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|
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|
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|
|
|
|
|
|
|
|
|
|
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|
|
|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 1 |
+
# CMap-GSE106127-CGS-mean-landmark978-zscore-v1.1
|
| 2 |
+
|
| 3 |
+
Embedding ID: `cmap_gse106127_cgs_mean_landmark978_zscore`
|
| 4 |
+
|
| 5 |
+
Former processing ID: `cmap_gse106127_cgs_mean_landmark978_zscore_v1_1`
|
| 6 |
+
|
| 7 |
+
## Public files
|
| 8 |
+
|
| 9 |
+
- `embeddings.npz`: compressed NumPy archive containing the embedding matrix under key `embeddings`.
|
| 10 |
+
- `genes.tsv`: row metadata table. Row order matches the embedding matrix.
|
| 11 |
+
- `metadata.json`: machine-readable provenance and processing metadata.
|
| 12 |
+
- `README.md`: this per-embedding documentation file.
|
| 13 |
+
|
| 14 |
+
## Matrix
|
| 15 |
+
|
| 16 |
+
- Shape: `4070 genes × 978 dimensions`
|
| 17 |
+
- Dtype: `float32`
|
| 18 |
+
- NPZ array key: `embeddings`
|
| 19 |
+
|
| 20 |
+
The row order is authoritative:
|
| 21 |
+
|
| 22 |
+
```text
|
| 23 |
+
embeddings.npz['embeddings'][i, :] corresponds to genes.tsv row i
|
| 24 |
+
```
|
| 25 |
+
|
| 26 |
+
## Loading example
|
| 27 |
+
|
| 28 |
+
```python
|
| 29 |
+
import numpy as np
|
| 30 |
+
import pandas as pd
|
| 31 |
+
|
| 32 |
+
with np.load('embeddings.npz') as z:
|
| 33 |
+
X = z['embeddings']
|
| 34 |
+
|
| 35 |
+
genes = pd.read_csv('genes.tsv', sep='\t')
|
| 36 |
+
assert X.shape[0] == len(genes)
|
| 37 |
+
```
|
| 38 |
+
|
| 39 |
+
## genes.tsv columns
|
| 40 |
+
|
| 41 |
+
| Column | Non-empty values | Unique values | Example values | Meaning |
|
| 42 |
+
|---|---:|---:|---|---|
|
| 43 |
+
| `embedding_row` | 4070 | 4070 | 0<br>1<br>2<br>3 | Zero-based row index in this embedding matrix and genes.tsv file. |
|
| 44 |
+
| `ensembl_gene_id` | 4070 | 4070 | ENSG00000000003<br>ENSG00000000457<br>ENSG00000000938<br>ENSG00000001084 | Ensembl gene identifier; main stable identifier used to align genes across embeddings. |
|
| 45 |
+
| `gene_symbol` | 4070 | 4063 | TSPAN6<br>SCYL3<br>FGR<br>GCLC | Gene symbol associated with the Ensembl gene ID. |
|
| 46 |
+
| `gene_type` | 4070 | 1 | protein_coding | Gene biotype, usually protein_coding. |
|
| 47 |
+
| `entrez_id` | 4070 | 4063 | 7105<br>57147<br>2268<br>2729 | NCBI Entrez Gene identifier, when available. |
|
| 48 |
+
| `uniprot_id` | 4070 | 4060 | O43657<br>Q8IZE3<br>P09769<br>P48506 | UniProt accession or identifier, when available. |
|
| 49 |
+
| `source_gene_symbol` | 4070 | 4063 | TSPAN6<br>SCYL3<br>FGR<br>GCLC | Original gene symbol from the source before final mapping. |
|
| 50 |
+
| `n_cgs_signatures` | 4070 | 6 | 9<br>1<br>8<br>7 | TODO: define this source-specific column during manual curation. |
|
| 51 |
+
| `n_cell_lines` | 4070 | 6 | 9<br>1<br>8<br>7 | TODO: define this source-specific column during manual curation. |
|
| 52 |
+
|
| 53 |
+
## Basic metadata
|
| 54 |
+
|
| 55 |
+
| Field | Value |
|
| 56 |
+
|---|---|
|
| 57 |
+
| `status` | processed_qc_passed |
|
| 58 |
+
| `modality` | perturbational transcriptomics / L1000 consensus genetic perturbation signatures |
|
| 59 |
+
| `embedding_name` | CMap-GSE106127-CGS-mean-landmark978-zscore-v1.1 |
|
| 60 |
+
|
| 61 |
+
## Detailed processing notes
|
| 62 |
+
|
| 63 |
+
TODO: manually paste and curate the processing explanation for this embedding from the central project README.
|
| 64 |
+
|
| 65 |
+
Please include, when relevant:
|
| 66 |
+
|
| 67 |
+
- original source/model/checkpoint;
|
| 68 |
+
- whether the embedding was downloaded or generated locally;
|
| 69 |
+
- input data used;
|
| 70 |
+
- identifier mapping and filtering decisions;
|
| 71 |
+
- pooling, aggregation, PCA, or normalization method;
|
| 72 |
+
- coverage and important caveats;
|
| 73 |
+
- license or redistribution notes.
|
data/embeddings/{cmap_gse106127_cgs_mean_landmark978_zscore_v1_1/cmap_gse106127_cgs_mean_landmark978_zscore_v1_1_embeddings.npz → cmap_gse106127_cgs_mean_landmark978_zscore/embeddings.npz}
RENAMED
|
File without changes
|
data/embeddings/{cmap_gse106127_cgs_mean_landmark978_zscore_v1_1/cmap_gse106127_cgs_mean_landmark978_zscore_v1_1_genes.tsv → cmap_gse106127_cgs_mean_landmark978_zscore/genes.tsv}
RENAMED
|
File without changes
|
data/embeddings/{cmap_gse106127_cgs_mean_landmark978_zscore_v1_1/cmap_gse106127_cgs_mean_landmark978_zscore_v1_1_metadata.json → cmap_gse106127_cgs_mean_landmark978_zscore/metadata.json}
RENAMED
|
@@ -34,5 +34,13 @@
|
|
| 34 |
"mapping_report": "/local/home/dtabares/data/processed_embeddings/cmap_gse106127_cgs_mean_landmark978_zscore_v1_1/mapping_report.txt",
|
| 35 |
"unmapped_master_genes": "/local/home/dtabares/reports/mapping_reports/cmap_gse106127_cgs_mean_landmark978_zscore_v1_1/unmapped_master_genes.tsv",
|
| 36 |
"unmapped_source_gene_symbols": "/local/home/dtabares/reports/mapping_reports/cmap_gse106127_cgs_mean_landmark978_zscore_v1_1/unmapped_source_gene_symbols.tsv"
|
|
|
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|
|
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|
|
|
|
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|
|
|
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|
|
| 37 |
}
|
| 38 |
-
}
|
|
|
|
| 34 |
"mapping_report": "/local/home/dtabares/data/processed_embeddings/cmap_gse106127_cgs_mean_landmark978_zscore_v1_1/mapping_report.txt",
|
| 35 |
"unmapped_master_genes": "/local/home/dtabares/reports/mapping_reports/cmap_gse106127_cgs_mean_landmark978_zscore_v1_1/unmapped_master_genes.tsv",
|
| 36 |
"unmapped_source_gene_symbols": "/local/home/dtabares/reports/mapping_reports/cmap_gse106127_cgs_mean_landmark978_zscore_v1_1/unmapped_source_gene_symbols.tsv"
|
| 37 |
+
},
|
| 38 |
+
"embedding_id": "cmap_gse106127_cgs_mean_landmark978_zscore",
|
| 39 |
+
"former_processing_embedding_id": "cmap_gse106127_cgs_mean_landmark978_zscore_v1_1",
|
| 40 |
+
"public_file_structure": {
|
| 41 |
+
"embeddings": "embeddings.npz",
|
| 42 |
+
"genes": "genes.tsv",
|
| 43 |
+
"metadata": "metadata.json",
|
| 44 |
+
"readme": "README.md"
|
| 45 |
}
|
| 46 |
+
}
|
data/embeddings/deepnf_string_v12_ppmi_svd_fusion/README.md
ADDED
|
@@ -0,0 +1,79 @@
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
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|
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|
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|
|
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|
|
|
|
|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
|
|
|
|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 1 |
+
# deepNF-STRING-v12-PPMI-SVD-fusion-v1.1
|
| 2 |
+
|
| 3 |
+
Embedding ID: `deepnf_string_v12_ppmi_svd_fusion`
|
| 4 |
+
|
| 5 |
+
Former processing ID: `deepnf_string_v12_ppmi_svd_fusion_v1_1`
|
| 6 |
+
|
| 7 |
+
## Public files
|
| 8 |
+
|
| 9 |
+
- `embeddings.npz`: compressed NumPy archive containing the embedding matrix under key `embeddings`.
|
| 10 |
+
- `genes.tsv`: row metadata table. Row order matches the embedding matrix.
|
| 11 |
+
- `metadata.json`: machine-readable provenance and processing metadata.
|
| 12 |
+
- `README.md`: this per-embedding documentation file.
|
| 13 |
+
|
| 14 |
+
## Matrix
|
| 15 |
+
|
| 16 |
+
- Shape: `19071 genes × 256 dimensions`
|
| 17 |
+
- Dtype: `float32`
|
| 18 |
+
- NPZ array key: `embeddings`
|
| 19 |
+
|
| 20 |
+
The row order is authoritative:
|
| 21 |
+
|
| 22 |
+
```text
|
| 23 |
+
embeddings.npz['embeddings'][i, :] corresponds to genes.tsv row i
|
| 24 |
+
```
|
| 25 |
+
|
| 26 |
+
## Loading example
|
| 27 |
+
|
| 28 |
+
```python
|
| 29 |
+
import numpy as np
|
| 30 |
+
import pandas as pd
|
| 31 |
+
|
| 32 |
+
with np.load('embeddings.npz') as z:
|
| 33 |
+
X = z['embeddings']
|
| 34 |
+
|
| 35 |
+
genes = pd.read_csv('genes.tsv', sep='\t')
|
| 36 |
+
assert X.shape[0] == len(genes)
|
| 37 |
+
```
|
| 38 |
+
|
| 39 |
+
## genes.tsv columns
|
| 40 |
+
|
| 41 |
+
| Column | Non-empty values | Unique values | Example values | Meaning |
|
| 42 |
+
|---|---:|---:|---|---|
|
| 43 |
+
| `ensembl_gene_id` | 19071 | 19071 | ENSG00000000003<br>ENSG00000000005<br>ENSG00000000419<br>ENSG00000000457 | Ensembl gene identifier; main stable identifier used to align genes across embeddings. |
|
| 44 |
+
| `gene_symbol` | 19071 | 19071 | TSPAN6<br>TNMD<br>DPM1<br>SCYL3 | Gene symbol associated with the Ensembl gene ID. |
|
| 45 |
+
| `gene_type` | 19071 | 1 | protein_coding | Gene biotype, usually protein_coding. |
|
| 46 |
+
| `entrez_id` | 18908 | 18909 | 7105<br>64102<br>8813<br>57147 | NCBI Entrez Gene identifier, when available. |
|
| 47 |
+
| `uniprot_id` | 19060 | 19010 | O43657<br>Q9H2S6<br>O60762<br>Q8IZE3 | UniProt accession or identifier, when available. |
|
| 48 |
+
| `canonical_transcript_id` | 19071 | 19071 | ENST00000373020<br>ENST00000373031<br>ENST00000371588<br>ENST00000367771 | Canonical transcript identifier recorded or used for this gene. |
|
| 49 |
+
| `canonical_protein_id` | 19071 | 19071 | ENSP00000362111<br>ENSP00000362122<br>ENSP00000360644<br>ENSP00000356745 | Canonical protein identifier recorded or used for this gene. |
|
| 50 |
+
| `source_embedding` | 19071 | 1 | deepNF-STRING-v12-PPMI-SVD-fusion-v1.1 | Name of the original source embedding. |
|
| 51 |
+
| `source_identifier_type` | 19071 | 1 | STRING protein ID / Ensembl protein ID | Type of source identifier used by the original embedding. |
|
| 52 |
+
| `source_key_count` | 19071 | 3 | 1<br>2<br>3 | Number of source keys mapped or collapsed to this final gene. |
|
| 53 |
+
| `source_keys_examples` | 19071 | 19071 | 9606.ENSP00000362111<br>9606.ENSP00000362122<br>9606.ENSP00000360638<br>9606.ENSP00000356746 | Example source keys mapped to this final gene. |
|
| 54 |
+
| `source_row_indices_examples` | 19071 | 19071 | 10924<br>10928<br>10628<br>9850 | Example source row indices mapped to this final gene. |
|
| 55 |
+
| `mapping_methods` | 19071 | 12 | ensembl_protein_id_exact;string_alias_entrez;string_id_exact;string_preferred_symbol<br>ensembl_protein_id_exact;string_alias_entrez;string_id_exact<br>ensembl_protein_id_exact;string_alias_entrez;string_id_exact;ensembl_protein_id_exact;string_alias_entrez;string_id_exact;string_preferred_symbol<br>string_alias_entrez;string_preferred_symbol | Mapping methods used to connect source records to the master gene table. |
|
| 56 |
+
|
| 57 |
+
## Basic metadata
|
| 58 |
+
|
| 59 |
+
| Field | Value |
|
| 60 |
+
|---|---|
|
| 61 |
+
| `modality` | STRING network multimodal sparse PPMI/SVD fusion |
|
| 62 |
+
| `embedding_name` | deepNF-STRING-v12-PPMI-SVD-fusion-v1.1 |
|
| 63 |
+
| `download_source` | STRING v12 human protein.links.detailed, protein.info, and protein.aliases files |
|
| 64 |
+
| `original_model_or_method` | deepNF: deep network fusion for protein function prediction |
|
| 65 |
+
| `embedding_generated_by` | Daniel locally from STRING v12 channel networks |
|
| 66 |
+
|
| 67 |
+
## Detailed processing notes
|
| 68 |
+
|
| 69 |
+
TODO: manually paste and curate the processing explanation for this embedding from the central project README.
|
| 70 |
+
|
| 71 |
+
Please include, when relevant:
|
| 72 |
+
|
| 73 |
+
- original source/model/checkpoint;
|
| 74 |
+
- whether the embedding was downloaded or generated locally;
|
| 75 |
+
- input data used;
|
| 76 |
+
- identifier mapping and filtering decisions;
|
| 77 |
+
- pooling, aggregation, PCA, or normalization method;
|
| 78 |
+
- coverage and important caveats;
|
| 79 |
+
- license or redistribution notes.
|
data/embeddings/{deepnf_string_v12_ppmi_svd_fusion_v1_1/deepnf_string_v12_ppmi_svd_fusion_v1_1_embeddings.npz → deepnf_string_v12_ppmi_svd_fusion/embeddings.npz}
RENAMED
|
File without changes
|
data/embeddings/{deepnf_string_v12_ppmi_svd_fusion_v1_1/deepnf_string_v12_ppmi_svd_fusion_v1_1_genes.tsv → deepnf_string_v12_ppmi_svd_fusion/genes.tsv}
RENAMED
|
File without changes
|
data/embeddings/{deepnf_string_v12_ppmi_svd_fusion_v1_1/deepnf_string_v12_ppmi_svd_fusion_v1_1_metadata.json → deepnf_string_v12_ppmi_svd_fusion/metadata.json}
RENAMED
|
@@ -144,5 +144,13 @@
|
|
| 144 |
"unmapped_tsv": "/local/home/dtabares/reports/mapping_reports/deepnf_string_v12_ppmi_svd_fusion_v1_1_unmapped_source_identifiers.tsv",
|
| 145 |
"ambiguous_tsv": "/local/home/dtabares/reports/mapping_reports/deepnf_string_v12_ppmi_svd_fusion_v1_1_ambiguous_source_identifiers.tsv",
|
| 146 |
"duplicates_tsv": "/local/home/dtabares/reports/mapping_reports/deepnf_string_v12_ppmi_svd_fusion_v1_1_duplicate_final_mappings.tsv"
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 147 |
}
|
| 148 |
-
}
|
|
|
|
| 144 |
"unmapped_tsv": "/local/home/dtabares/reports/mapping_reports/deepnf_string_v12_ppmi_svd_fusion_v1_1_unmapped_source_identifiers.tsv",
|
| 145 |
"ambiguous_tsv": "/local/home/dtabares/reports/mapping_reports/deepnf_string_v12_ppmi_svd_fusion_v1_1_ambiguous_source_identifiers.tsv",
|
| 146 |
"duplicates_tsv": "/local/home/dtabares/reports/mapping_reports/deepnf_string_v12_ppmi_svd_fusion_v1_1_duplicate_final_mappings.tsv"
|
| 147 |
+
},
|
| 148 |
+
"embedding_id": "deepnf_string_v12_ppmi_svd_fusion",
|
| 149 |
+
"former_processing_embedding_id": "deepnf_string_v12_ppmi_svd_fusion_v1_1",
|
| 150 |
+
"public_file_structure": {
|
| 151 |
+
"embeddings": "embeddings.npz",
|
| 152 |
+
"genes": "genes.tsv",
|
| 153 |
+
"metadata": "metadata.json",
|
| 154 |
+
"readme": "README.md"
|
| 155 |
}
|
| 156 |
+
}
|
data/embeddings/deepsea_tss_1kb_epigenomic_probs/README.md
ADDED
|
@@ -0,0 +1,79 @@
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
|
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|
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|
|
|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 1 |
+
# DeepSEA-TSS-1kb-epigenomic-probabilities-zscore-v1.1
|
| 2 |
+
|
| 3 |
+
Embedding ID: `deepsea_tss_1kb_epigenomic_probs`
|
| 4 |
+
|
| 5 |
+
Former processing ID: `deepsea_tss_1kb_epigenomic_probs_v1_1`
|
| 6 |
+
|
| 7 |
+
## Public files
|
| 8 |
+
|
| 9 |
+
- `embeddings.npz`: compressed NumPy archive containing the embedding matrix under key `embeddings`.
|
| 10 |
+
- `genes.tsv`: row metadata table. Row order matches the embedding matrix.
|
| 11 |
+
- `metadata.json`: machine-readable provenance and processing metadata.
|
| 12 |
+
- `README.md`: this per-embedding documentation file.
|
| 13 |
+
|
| 14 |
+
## Matrix
|
| 15 |
+
|
| 16 |
+
- Shape: `20097 genes × 919 dimensions`
|
| 17 |
+
- Dtype: `float32`
|
| 18 |
+
- NPZ array key: `embeddings`
|
| 19 |
+
|
| 20 |
+
The row order is authoritative:
|
| 21 |
+
|
| 22 |
+
```text
|
| 23 |
+
embeddings.npz['embeddings'][i, :] corresponds to genes.tsv row i
|
| 24 |
+
```
|
| 25 |
+
|
| 26 |
+
## Loading example
|
| 27 |
+
|
| 28 |
+
```python
|
| 29 |
+
import numpy as np
|
| 30 |
+
import pandas as pd
|
| 31 |
+
|
| 32 |
+
with np.load('embeddings.npz') as z:
|
| 33 |
+
X = z['embeddings']
|
| 34 |
+
|
| 35 |
+
genes = pd.read_csv('genes.tsv', sep='\t')
|
| 36 |
+
assert X.shape[0] == len(genes)
|
| 37 |
+
```
|
| 38 |
+
|
| 39 |
+
## genes.tsv columns
|
| 40 |
+
|
| 41 |
+
| Column | Non-empty values | Unique values | Example values | Meaning |
|
| 42 |
+
|---|---:|---:|---|---|
|
| 43 |
+
| `ensembl_gene_id` | 20097 | 20097 | ENSG00000000003<br>ENSG00000000005<br>ENSG00000000419<br>ENSG00000000457 | Ensembl gene identifier; main stable identifier used to align genes across embeddings. |
|
| 44 |
+
| `gene_symbol` | 20097 | 20070 | TSPAN6<br>TNMD<br>DPM1<br>SCYL3 | Gene symbol associated with the Ensembl gene ID. |
|
| 45 |
+
| `entrez_id` | 19545 | 19511 | 7105<br>64102<br>8813<br>57147 | NCBI Entrez Gene identifier, when available. |
|
| 46 |
+
| `uniprot_id` | 20045 | 19860 | O43657<br>Q9H2S6<br>O60762<br>Q8IZE3 | UniProt accession or identifier, when available. |
|
| 47 |
+
| `gene_type` | 20097 | 1 | protein_coding | Gene biotype, usually protein_coding. |
|
| 48 |
+
| `chromosome` | 20097 | 25 | chrX<br>chr20<br>chr1<br>chr6 | Chromosome for the gene or modeled interval. |
|
| 49 |
+
| `gene_start` | 20097 | 20039 | 100627108<br>100584936<br>50934852<br>169846981 | Gene start coordinate in the stated genome assembly. |
|
| 50 |
+
| `gene_end` | 20097 | 19988 | 100639991<br>100599885<br>50959140<br>169894267 | Gene end coordinate in the stated genome assembly. |
|
| 51 |
+
| `strand` | 20097 | 2 | -<br>+ | Genomic strand. |
|
| 52 |
+
| `tss_1based` | 20097 | 20047 | 100639991<br>100584936<br>50959140<br>169894267 | Transcription start site coordinate in 1-based coordinates. |
|
| 53 |
+
| `bed_start_0based` | 20097 | 20047 | 100639490<br>100584435<br>50958639<br>169893766 | BED-format interval start coordinate, 0-based. |
|
| 54 |
+
| `bed_end_0based` | 20097 | 20047 | 100640490<br>100585435<br>50959639<br>169894766 | BED-format interval end coordinate, half-open. |
|
| 55 |
+
| `bed_name` | 20097 | 20097 | ENSG00000000003|TSPAN6<br>ENSG00000000005|TNMD<br>ENSG00000000419|DPM1<br>ENSG00000000457|SCYL3 | BED interval name. |
|
| 56 |
+
| `assembly` | 20097 | 1 | GRCh38 | Genome assembly used for coordinates. |
|
| 57 |
+
| `gencode_release` | 20097 | 1 | 49 | GENCODE release used for annotation. |
|
| 58 |
+
|
| 59 |
+
## Basic metadata
|
| 60 |
+
|
| 61 |
+
| Field | Value |
|
| 62 |
+
|---|---|
|
| 63 |
+
| `status` | processed_qc_passed |
|
| 64 |
+
| `modality` | regulatory DNA / promoter-TSS sequence model |
|
| 65 |
+
| `embedding_name` | DeepSEA-TSS-1kb-epigenomic-probabilities-zscore-v1.1 |
|
| 66 |
+
|
| 67 |
+
## Detailed processing notes
|
| 68 |
+
|
| 69 |
+
TODO: manually paste and curate the processing explanation for this embedding from the central project README.
|
| 70 |
+
|
| 71 |
+
Please include, when relevant:
|
| 72 |
+
|
| 73 |
+
- original source/model/checkpoint;
|
| 74 |
+
- whether the embedding was downloaded or generated locally;
|
| 75 |
+
- input data used;
|
| 76 |
+
- identifier mapping and filtering decisions;
|
| 77 |
+
- pooling, aggregation, PCA, or normalization method;
|
| 78 |
+
- coverage and important caveats;
|
| 79 |
+
- license or redistribution notes.
|
data/embeddings/{deepsea_tss_1kb_epigenomic_probs_v1_1/deepsea_tss_1kb_epigenomic_probs_v1_1_embeddings.npz → deepsea_tss_1kb_epigenomic_probs/embeddings.npz}
RENAMED
|
File without changes
|
data/embeddings/{deepsea_tss_1kb_epigenomic_probs_v1_1/deepsea_tss_1kb_epigenomic_probs_v1_1_genes.tsv → deepsea_tss_1kb_epigenomic_probs/genes.tsv}
RENAMED
|
File without changes
|
data/embeddings/{deepsea_tss_1kb_epigenomic_probs_v1_1/deepsea_tss_1kb_epigenomic_probs_v1_1_metadata.json → deepsea_tss_1kb_epigenomic_probs/metadata.json}
RENAMED
|
@@ -26,5 +26,13 @@
|
|
| 26 |
"feature_columns": "deepsea_feature_columns.tsv",
|
| 27 |
"skipped_windows": "/local/home/dtabares/reports/mapping_reports/deepsea_tss_1kb_epigenomic_probs_v1_1/skipped_tss_windows.tsv"
|
| 28 |
},
|
| 29 |
-
"created_at": "2026-07-09T10:41:32"
|
| 30 |
-
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|
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|
| 26 |
"feature_columns": "deepsea_feature_columns.tsv",
|
| 27 |
"skipped_windows": "/local/home/dtabares/reports/mapping_reports/deepsea_tss_1kb_epigenomic_probs_v1_1/skipped_tss_windows.tsv"
|
| 28 |
},
|
| 29 |
+
"created_at": "2026-07-09T10:41:32",
|
| 30 |
+
"embedding_id": "deepsea_tss_1kb_epigenomic_probs",
|
| 31 |
+
"former_processing_embedding_id": "deepsea_tss_1kb_epigenomic_probs_v1_1",
|
| 32 |
+
"public_file_structure": {
|
| 33 |
+
"embeddings": "embeddings.npz",
|
| 34 |
+
"genes": "genes.tsv",
|
| 35 |
+
"metadata": "metadata.json",
|
| 36 |
+
"readme": "README.md"
|
| 37 |
+
}
|
| 38 |
+
}
|
data/embeddings/depmap_crispr_gene_effect_pca256/README.md
ADDED
|
@@ -0,0 +1,73 @@
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|
| 1 |
+
# DepMap-CRISPRGeneEffect-PCA256-v1.1
|
| 2 |
+
|
| 3 |
+
Embedding ID: `depmap_crispr_gene_effect_pca256`
|
| 4 |
+
|
| 5 |
+
Former processing ID: `depmap_crispr_gene_effect_pca256_v1_1`
|
| 6 |
+
|
| 7 |
+
## Public files
|
| 8 |
+
|
| 9 |
+
- `embeddings.npz`: compressed NumPy archive containing the embedding matrix under key `embeddings`.
|
| 10 |
+
- `genes.tsv`: row metadata table. Row order matches the embedding matrix.
|
| 11 |
+
- `metadata.json`: machine-readable provenance and processing metadata.
|
| 12 |
+
- `README.md`: this per-embedding documentation file.
|
| 13 |
+
|
| 14 |
+
## Matrix
|
| 15 |
+
|
| 16 |
+
- Shape: `18562 genes × 256 dimensions`
|
| 17 |
+
- Dtype: `float32`
|
| 18 |
+
- NPZ array key: `embeddings`
|
| 19 |
+
|
| 20 |
+
The row order is authoritative:
|
| 21 |
+
|
| 22 |
+
```text
|
| 23 |
+
embeddings.npz['embeddings'][i, :] corresponds to genes.tsv row i
|
| 24 |
+
```
|
| 25 |
+
|
| 26 |
+
## Loading example
|
| 27 |
+
|
| 28 |
+
```python
|
| 29 |
+
import numpy as np
|
| 30 |
+
import pandas as pd
|
| 31 |
+
|
| 32 |
+
with np.load('embeddings.npz') as z:
|
| 33 |
+
X = z['embeddings']
|
| 34 |
+
|
| 35 |
+
genes = pd.read_csv('genes.tsv', sep='\t')
|
| 36 |
+
assert X.shape[0] == len(genes)
|
| 37 |
+
```
|
| 38 |
+
|
| 39 |
+
## genes.tsv columns
|
| 40 |
+
|
| 41 |
+
| Column | Non-empty values | Unique values | Example values | Meaning |
|
| 42 |
+
|---|---:|---:|---|---|
|
| 43 |
+
| `embedding_row` | 18562 | 18562 | 0<br>1<br>2<br>3 | Zero-based row index in this embedding matrix and genes.tsv file. |
|
| 44 |
+
| `ensembl_gene_id` | 18562 | 18562 | ENSG00000000003<br>ENSG00000000005<br>ENSG00000000419<br>ENSG00000000457 | Ensembl gene identifier; main stable identifier used to align genes across embeddings. |
|
| 45 |
+
| `gene_symbol` | 18562 | 18537 | TSPAN6<br>TNMD<br>DPM1<br>SCYL3 | Gene symbol associated with the Ensembl gene ID. |
|
| 46 |
+
| `gene_type` | 18562 | 1 | protein_coding | Gene biotype, usually protein_coding. |
|
| 47 |
+
| `entrez_id` | 18562 | 18529 | 7105<br>64102<br>8813<br>57147 | NCBI Entrez Gene identifier, when available. |
|
| 48 |
+
| `uniprot_id` | 18562 | 18498 | O43657<br>Q9H2S6<br>O60762<br>Q8IZE3 | UniProt accession or identifier, when available. |
|
| 49 |
+
| `source_entrez_id` | 18562 | 18529 | 7105<br>64102<br>8813<br>57147 | Entrez Gene identifier from the original source before final mapping. |
|
| 50 |
+
| `source_gene_symbol` | 18562 | 18529 | TSPAN6<br>TNMD<br>DPM1<br>SCYL3 | Original gene symbol from the source before final mapping. |
|
| 51 |
+
| `source_column` | 18562 | 18529 | TSPAN6 (7105)<br>TNMD (64102)<br>DPM1 (8813)<br>SCYL3 (57147) | TODO: define this source-specific column during manual curation. |
|
| 52 |
+
|
| 53 |
+
## Basic metadata
|
| 54 |
+
|
| 55 |
+
| Field | Value |
|
| 56 |
+
|---|---|
|
| 57 |
+
| `status` | processed_qc_passed |
|
| 58 |
+
| `modality` | functional genomics / CRISPR dependency |
|
| 59 |
+
| `embedding_name` | DepMap-CRISPRGeneEffect-PCA256-v1.1 |
|
| 60 |
+
|
| 61 |
+
## Detailed processing notes
|
| 62 |
+
|
| 63 |
+
TODO: manually paste and curate the processing explanation for this embedding from the central project README.
|
| 64 |
+
|
| 65 |
+
Please include, when relevant:
|
| 66 |
+
|
| 67 |
+
- original source/model/checkpoint;
|
| 68 |
+
- whether the embedding was downloaded or generated locally;
|
| 69 |
+
- input data used;
|
| 70 |
+
- identifier mapping and filtering decisions;
|
| 71 |
+
- pooling, aggregation, PCA, or normalization method;
|
| 72 |
+
- coverage and important caveats;
|
| 73 |
+
- license or redistribution notes.
|
data/embeddings/{depmap_crispr_gene_effect_pca256_v1_1/depmap_crispr_gene_effect_pca256_v1_1_embeddings.npz → depmap_crispr_gene_effect_pca256/embeddings.npz}
RENAMED
|
File without changes
|
data/embeddings/{depmap_crispr_gene_effect_pca256_v1_1/depmap_crispr_gene_effect_pca256_v1_1_genes.tsv → depmap_crispr_gene_effect_pca256/genes.tsv}
RENAMED
|
File without changes
|
data/embeddings/{depmap_crispr_gene_effect_pca256_v1_1/depmap_crispr_gene_effect_pca256_v1_1_metadata.json → depmap_crispr_gene_effect_pca256/metadata.json}
RENAMED
|
@@ -32,5 +32,13 @@
|
|
| 32 |
"metadata": "/local/home/dtabares/data/processed_embeddings/depmap_crispr_gene_effect_pca256_v1_1/metadata.json",
|
| 33 |
"mapping_report": "/local/home/dtabares/data/processed_embeddings/depmap_crispr_gene_effect_pca256_v1_1/mapping_report.txt",
|
| 34 |
"unmapped_master_genes": "/local/home/dtabares/reports/mapping_reports/depmap_crispr_gene_effect_pca256_v1_1/unmapped_master_genes.tsv"
|
|
|
|
|
|
|
|
|
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|
|
|
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|
|
|
|
|
|
|
|
|
|
|
| 35 |
}
|
| 36 |
-
}
|
|
|
|
| 32 |
"metadata": "/local/home/dtabares/data/processed_embeddings/depmap_crispr_gene_effect_pca256_v1_1/metadata.json",
|
| 33 |
"mapping_report": "/local/home/dtabares/data/processed_embeddings/depmap_crispr_gene_effect_pca256_v1_1/mapping_report.txt",
|
| 34 |
"unmapped_master_genes": "/local/home/dtabares/reports/mapping_reports/depmap_crispr_gene_effect_pca256_v1_1/unmapped_master_genes.tsv"
|
| 35 |
+
},
|
| 36 |
+
"embedding_id": "depmap_crispr_gene_effect_pca256",
|
| 37 |
+
"former_processing_embedding_id": "depmap_crispr_gene_effect_pca256_v1_1",
|
| 38 |
+
"public_file_structure": {
|
| 39 |
+
"embeddings": "embeddings.npz",
|
| 40 |
+
"genes": "genes.tsv",
|
| 41 |
+
"metadata": "metadata.json",
|
| 42 |
+
"readme": "README.md"
|
| 43 |
}
|
| 44 |
+
}
|
data/embeddings/dnabert2_117m_cds/README.md
ADDED
|
@@ -0,0 +1,69 @@
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 1 |
+
# dnabert2_117m_cds_v1_1
|
| 2 |
+
|
| 3 |
+
Embedding ID: `dnabert2_117m_cds`
|
| 4 |
+
|
| 5 |
+
Former processing ID: `dnabert2_117m_cds_v1_1`
|
| 6 |
+
|
| 7 |
+
## Public files
|
| 8 |
+
|
| 9 |
+
- `embeddings.npz`: compressed NumPy archive containing the embedding matrix under key `embeddings`.
|
| 10 |
+
- `genes.tsv`: row metadata table. Row order matches the embedding matrix.
|
| 11 |
+
- `metadata.json`: machine-readable provenance and processing metadata.
|
| 12 |
+
- `README.md`: this per-embedding documentation file.
|
| 13 |
+
|
| 14 |
+
## Matrix
|
| 15 |
+
|
| 16 |
+
- Shape: `20085 genes × 768 dimensions`
|
| 17 |
+
- Dtype: `float32`
|
| 18 |
+
- NPZ array key: `embeddings`
|
| 19 |
+
|
| 20 |
+
The row order is authoritative:
|
| 21 |
+
|
| 22 |
+
```text
|
| 23 |
+
embeddings.npz['embeddings'][i, :] corresponds to genes.tsv row i
|
| 24 |
+
```
|
| 25 |
+
|
| 26 |
+
## Loading example
|
| 27 |
+
|
| 28 |
+
```python
|
| 29 |
+
import numpy as np
|
| 30 |
+
import pandas as pd
|
| 31 |
+
|
| 32 |
+
with np.load('embeddings.npz') as z:
|
| 33 |
+
X = z['embeddings']
|
| 34 |
+
|
| 35 |
+
genes = pd.read_csv('genes.tsv', sep='\t')
|
| 36 |
+
assert X.shape[0] == len(genes)
|
| 37 |
+
```
|
| 38 |
+
|
| 39 |
+
## genes.tsv columns
|
| 40 |
+
|
| 41 |
+
| Column | Non-empty values | Unique values | Example values | Meaning |
|
| 42 |
+
|---|---:|---:|---|---|
|
| 43 |
+
| `ensembl_gene_id` | 20085 | 20085 | ENSG00000000003<br>ENSG00000000005<br>ENSG00000000419<br>ENSG00000000457 | Ensembl gene identifier; main stable identifier used to align genes across embeddings. |
|
| 44 |
+
| `transcript_id` | 20085 | 20085 | ENST00000373020<br>ENST00000373031<br>ENST00000371588<br>ENST00000367771 | Transcript identifier used for sequence-based processing. |
|
| 45 |
+
| `dnabert2_sequence_length` | 20085 | 2255 | 738<br>954<br>783<br>2067 | TODO: define this source-specific column during manual curation. |
|
| 46 |
+
| `num_chunks` | 20085 | 19 | 1<br>2<br>3<br>4 | Number of chunks/windows used when the input was too long. |
|
| 47 |
+
| `was_chunked` | 20085 | 2 | False<br>True | Whether the input sequence was split into chunks. |
|
| 48 |
+
|
| 49 |
+
## Basic metadata
|
| 50 |
+
|
| 51 |
+
| Field | Value |
|
| 52 |
+
|---|---|
|
| 53 |
+
| `status` | processed_qc_passed |
|
| 54 |
+
| `embedding_name` | dnabert2_117m_cds_v1_1 |
|
| 55 |
+
| `pooling_strategy` | Mean pooling over final-layer non-special token embeddings. Long CDS sequences split into nucleotide chunks, then length-weighted mean of chunk-level embeddings. |
|
| 56 |
+
|
| 57 |
+
## Detailed processing notes
|
| 58 |
+
|
| 59 |
+
TODO: manually paste and curate the processing explanation for this embedding from the central project README.
|
| 60 |
+
|
| 61 |
+
Please include, when relevant:
|
| 62 |
+
|
| 63 |
+
- original source/model/checkpoint;
|
| 64 |
+
- whether the embedding was downloaded or generated locally;
|
| 65 |
+
- input data used;
|
| 66 |
+
- identifier mapping and filtering decisions;
|
| 67 |
+
- pooling, aggregation, PCA, or normalization method;
|
| 68 |
+
- coverage and important caveats;
|
| 69 |
+
- license or redistribution notes.
|
data/embeddings/{dnabert2_117m_cds_v1_1/dnabert2_117m_cds_v1_1_embeddings.npz → dnabert2_117m_cds/embeddings.npz}
RENAMED
|
File without changes
|
data/embeddings/{dnabert2_117m_cds_v1_1/dnabert2_117m_cds_v1_1_genes.tsv → dnabert2_117m_cds/genes.tsv}
RENAMED
|
File without changes
|