PMID int64 35.7M 36.4M | Title/Abstract stringlengths 22 8.78k | MeshTerms stringlengths 7 101 | SemanticTypes stringlengths 4 64 |
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36,293,506 | transcriptom physiolog analys reveal potenti gene involv photoperiod regul caroten accumul mechan endocarp cucumb cucumi sativus l fruit accumul carotenoid plant key nutrit qualiti mani horticultur crop although structur gene encod biosynthet enzym well character littl known regard photoperiod mediat carotenoid accumul... | D018553;D044602 | T116;T168;T126;T169;T002 |
36,293,505 | use comput drug gene analysi identifi novel therapeut candid retin neuroprotect retin cell death respons irrevers vision loss mani retin disord commerci approv treatment current avail attenu retin cell loss preserv vision seek identifi chemicalsdrug thorough studi biolog function possess neuroprotect effect retina use ... | D018696;D010126 | T121;T103;T169 |
36,293,504 | oncoly virotherapi prostat cancer light fire winter common cancer genitourinari system prostat cancer pca global men health problem whose treatment urgent research issu treatment option pca includ activ surveil surgeri endocrin therapi chemotherapi radiat therapi immunotherapi etc howev cancer progress effect treatment... | D050130;D011471;D050504 | T061;T005;T191 |
36,293,503 | small extracellular vesicl hypox tripl negat breast cancer cell induc oxygen depend cell invas hypoxia condit low oxygen frequent found tripl negat breast tumor tnbc promot extracellular vesicl ev secret favor cell invas complex process cell morpholog alter dynam focal adhes spot creat ecm remodel investig invas proper... | D064726;D000067128 | T026;T191 |
36,293,502 | serratiopeptidas affect physiolog pseudomona aeruginosa isol cystic fibrosi patient pseudomona aeruginosa frequent involv cystic fibrosi cf airway infect biofilm motil product toxin invas host cell differ factor increas p aeruginosa virul sessil phenotyp offer protect bacteri cell resist antimicrobi host immun attack m... | D003550;D011552 | T047 |
36,293,501 | overview polyethylen terephthal pet hydrolas effort tailor enzym improv plastic degrad plastic microplast pollut global threat affect ecosystem current generat reach much metric ton peryear soil ecosystem compris agricultur land act microplast sink though impact could unexpect far reach troubl plastic form polyethylen ... | D011093;D004785 | T131;T122;T109 |
36,293,500 | pharmacolog therapeut applic esculetin esculetin coumarin compound belong class benzopyron enrich various plant sonchus grandifolius aesculus turbinata etc free radic lead develop oxid stress caus inflamm arthriti cancer diabet fatti liver diseas etc reduc efficaci anticanc drug activ inflammatori signal pathway degrad... | D000970;D001168 | T121;T047;T109 |
36,293,499 | ccbe essenti epicardi function myocardium develop epicardium singl cell layer mesotheli cell play critic role heart develop contribut differ cardiac cell type develop heart epitheli mesenchym transit emt moreov epicardium sourc secret growth factor promot myocardi growth ccbe secret extracellular matrix protein express... | D006321;D038081 | T023;T038 |
36,293,498 | associ chang pattern antinuclear autoantibodi immun checkpoint inhibit therapi develop sever immun relat advers event immun relat advers event ira unpredict autoimmun like toxic induc immun checkpoint inhibitor ici ira consequ breakdown self toler ici induc autoantibodi format presenc antinuclear autoantibodi ana repor... | D000074322;D009369 | T129;T121;T191;T116 |
36,293,497 | unpredict aberr splice product identifi postmortem sudden cardiac death sampl molecular screen pathogen mutat sudden cardiac death scd relat gene common practic scd case howev test result may lead uncertainti identif variant unknown signific vus occur total identifi variant due lack experiment studi genet variant affec... | D012326;D016757 | T045;T046 |
36,293,496 | abnorm express synapt extrasynapt gaba receptor subunit dystrophin defici mdx mous duchenn muscular dystrophi dmd neurodevelopment disord primarili caus loss full length dp dystrophin muscl brain basi central comorbid dmd unclear brain dystrophin play role cluster central gamma aminobutyr acid receptor gaba rs loss mdx... | D016189;D020388 | T123;T047;T116 |
36,293,495 | select revers dipolar cycloaddit oxoindolin yliden acet nitron synthesi function spiroisoxazolidin dipolar cycloaddit oxoindolin yliden acet function aldo ketonitron proceed good select provid new high function spiroisoxazolidin characterist featur reaction revers allow control diastereoselect cycloaddit reduct obtain ... | D013141 | T109 |
36,293,494 | cabozantinib load plga nanoparticl potenti adjuv strategi surgic resect high risk non metastat renal cell carcinoma patient high risk non metastat renal cell carcinoma rcc risk metastat relaps follow nephrectomi cabozantinib cz potent multitarget tyrosin kinas inhibitor interfer angiogenesi immunosuppress associ surger... | D002292;D053758;D007680;D008175 | T191;T073 |
36,293,493 | identifi hub gene associ neoadjuv chemotherapi resist breast cancer potenti drug repurpos develop precis medicin breast cancer second lead caus morbid mortal women worldwid despit advanc clinic applic neoadjuv chemotherapi nac drug resist remain major concern hinder treatment efficaci thus identifi key gene involv driv... | D001943;D035683 | T123;T191;T114 |
36,293,492 | matrix metalloproteinas gene polymorph associ breast cancer caucasian women russia conduct studi explor associ matrix metalloproteinas mmp gene polymorph breast cancer bc risk caucasian women russia total affect bc unaffect cancer free women includ case control retrospect studi bc relat gene previous studi ten singl nu... | D020780;D001943 | T191;T126;T116 |
36,293,491 | experiment evalu quantum dot antibodi conjug surfac plasmon reson spectroscopi applic antibodi function quantum dot qds differ area wide describ literatur howev standard routin method obtain inform conjug effici qds antibodi term interact function qds specif antigen still lack herein surfac plasmon reson spr spectrosco... | D045663 | T073 |
36,293,490 | promis therapi atrial fibril ventricular tachycardia sudden cardiac death due arrhythmia atrial fibril ventricular tachycardia account death myocardi infarct increas burden atrial fibril ventricular tachycardia structur electr remodel heart current manag new onset atrial fibril includ electr cardiovers high convers rat... | D001281;D017180;D017115 | T061;T047;T046 |
36,293,489 | conform heterogen frustrat tumor suppressor p tune punctual mutat conform heterogen p tumor suppressor wild type pwt mutat form investig comput approach includ model atom molecular dynam md simul four differ punctual mutat prh prq prh prw known affect dna bind belong frequent hot spot mutat human cancer taken consider ... | D016159;D005639 | T123;T116;T041 |
36,293,488 | senp promot vsmc phenotyp switch via myocardin de sumoyl myocardin master regul smooth muscl cell smc differenti induc express smooth muscl specif gene direct associ serum respons factor srf past two decad signific insight obtain regard regulatori control myocardin express transcript activ transcript post transcript po... | D058207;D026362 | T123;T116;T044 |
36,293,487 | monodelphi domestica induc pluripot stem cell reveal metatherian pluripot architectur marsupi power compar model understand mammalian biolog howev uniqu characterist embryolog marsupi pluripot architectur remain fulli understood nobodi succeed develop embryon stem cell esc marsupi speci develop integr free ipsc reprogr... | D048309;D057026 | T015;T025 |
36,293,486 | cannabinoid cb receptor delet catecholaminerg neuron protect diet induc obes high calori diet chronic stress major contributor develop obes metabol disord two risk factor regul activ sympathet nervous system sns present studi show key role cannabinoid type receptor cb dopamin hydroxylas dbh express cell regul sns activ... | D009478;D002186 | T123;T121;T116;T109 |
36,293,485 | lipoteicho acid lipopolysaccharid affect p inflammatori marker modul promot inhibitori effect osteogen differenti lipoteicho acid lta lipopolysaccharid lps cell wall compon gram posit gram negat bacteria respect notabl oral microflora consist varieti bacteri speci osteomyel jaw caus dental infect present symptom bone r... | D008070;D014409 | T129;T116;T109 |
36,293,484 | toler adapt cell respons elicit micromonospora sp face tellurit toxic biolog physic chemic character intens use tellurium te industri applic along improp dispos te deriv caus accumul environ oxyanion tellurit teo solubl bioavail toxic te speci hand tellurium rare metalloid element whose natur suppli end short possibl e... | D013691;D008847 | T131;T196;T007 |
36,293,483 | lack npr increas vascular endotheli adhes induct integrin beta natriuret peptid receptor npr serv modul vascular endotheli homeostasi interact monocyt endotheli cell may initi endothelium dysfunct known earli hallmark atherosclerosi studi perform rna sequenc analysi aorta npr knockout npr mice found differenti express ... | D018799;D050197 | T129;T047;T046;T116 |
36,293,482 | mechan stimul alter chronic ethanol induc chang vta gaba neuron nac da releas measur withdraw therapeut activ mechanoreceptor mstim osteopathi chiropract acupunctur use hundr year myriad posit outcom previous shown modul fire rate neuron ventral tegment area vta dopamin da releas nucleus accumben nac area interest alco... | D017557;D004298 | T123;T023;T121;T109 |
36,293,481 | enhanc flame retard rigid polyurethan foam polyacrylamidemxen hydrogel nanocomposit coat rigid polyurethan foam rpuf wide use mani field high flammabl frequent releas larg amount toxic smoke combust limit applic hydrogel coat kind environment friend materi contain larg amount water benefici flame retard rpuf mxene two ... | D005411;D053761 | T120;T073 |
36,293,480 | restrict flavivirus interferon stimul gene shflcorf flavivirus genus flavivirus flavivirida famili includ mani arthropod born virus often caus life threaten diseas human hemorrhag enceph although flavivirus signific clinic impact becom appar flavivirus replic restrict cellular factor induc interferon ifn respons call i... | D005416;D000071244;D000071243;D004664;D004672 | T005;T047 |
36,293,479 | role dna methyl within cypa gene associ genet environment risk factor stress relat manifest schizophrenia genet environment influenc schizophrenia might converg dna methyl dnam within loci associ diseas implic respons environment stress examin whether dnam within cypa hypothalamus pituitari adren axi gene situat within... | D019175;D012559 | T044;T048 |
36,293,478 | circul small ev mirna predictor patholog respons neo adjuv therapi breast cancer patient neo adjuv therapi nat increas use clinic treatment breast cancer bc patholog respons nat associ improv patient surviv howev current techniqu employ assess tumor respons signific limit small ev sev encapsul mirna emerg promis new bi... | D035683;D001943 | T123;T191;T114 |
36,293,477 | epigenet chang prion prion like neurodegen diseas recent advanc potenti biomark futur perspect prion diseas transmiss spongiform encephalopathi tses caus conform convers nativ cellular prion protein prp c abnorm infecti isoform call prp sc amyotroph later sclerosi alzheim parkinson huntington diseas also known prion li... | D011328;D019636;D017096;D035683 | T123;T116;T005;T114;T047 |
36,293,476 | mitochondria target polym micell stepwis respons releas gemcitabin destroy mitochondria nucleus combin antitumor chemotherapi mitochondri dna nuclear dna essenti genet materi play import role maintain normal metabol surviv prolifer cell construct mitochondria target stimuli respons nano drug deliveri system releas chem... | D008823;D000970 | T121;T109 |
36,293,475 | potenti urin proteom biomark focal segment glomerulosclerosi minim chang diseas primari focal segment glomerulosclerosi fsgs along minim chang diseas mcd diseas primari podocyt damag clinic manifest nephrot syndrom pathogenesi podocytopathi still unknown therefor search biomark diseas ongo aim determin proteom profil u... | D009402;D005923 | T047 |
36,293,474 | metabolom profil nephrot syndrom toward biomark discoveri nephrot syndrom ns kidney ill character excess proteinuria hypoalbuminemia edema hyperlipidemia may lead kidney failur necessit renal transplant end stage renal diseas cardiovascular issu mortal much common ns therefor present studi aim identifi potenti new biom... | D009404 | T047 |
36,293,473 | gper agonist g prevent wnt induc jun upregul ht colorect cancer cell women consist show lower incid mortal rate colorect cancer crc compar men epidemiolog evid support pivot role estrogen protect women crc estrogen protect effect crc main attribut estrogen receptor beta er howev express lost crc progress role g protein... | D051176;D015179 | T123;T191;T116 |
36,293,472 | anthocyanin accumul provid protect high light stress reduc photosynthesi appl leav photoprotect role anthocyanin remain controversi studi explor effect anthocyanin photosynthesi photoprotect use transgen galaxi gala appl plant overexpress mdmyb high light stress overexpress mdmyb dramat enhanc leaf anthocyanin accumul ... | D027845;D007887 | T168;T002 |
36,293,471 | use retinoid prevent treatment skin cancer updat review retinoid natur synthet vitamin deriv effect prevent treatment non melanoma skin cancer nmsc nmscs constitut heterogen group non melanocyt deriv skin cancer impos substanti burden patient healthcar system includ entiti basal cell carcinoma cutan squamous cell carci... | D012878;D002294;D002280 | T191 |
36,293,470 | hybrid coordin network remov pollut wastewat adsorpt properti two coordin polym result reaction dival metal ca co salt carboxyethyl phenyl phosphin acid present paper structur textur character adsorpt experi present adsorb materi prepar use hydrotherm procedur compound ca p ch ch cooh c h caceppa layer topolog phenyl g... | D014874;D004785 | T131 |
36,293,469 | adam adam novel player retinoblastoma carcinogenesi disintegrin metalloproteinas adam famili protein act sheddas import factor number patholog includ cancer suggest promis therapeut target studi present focus involv adam adam retinoblastoma rb common malign intraocular childhood tumor signific correl adam express level... | D012175;D039842;D035683;D019572 | T123;T191;T116;T114 |
36,293,468 | tlr pathway associ biomark subarachnoid hemorrhag sah potenti target futur anti inflammatori therapi subarachnoid hemorrhag associ sever neurolog deficit survivor among survivor initi bleed secondari brain injuri lead addit brain damag apart cerebr vasospasm secondari brain injuri main result cerebr inflamm take place ... | D013345;D001930 | T047;T046;T037 |
36,293,467 | strategi toward produc non polar dolomit nanoparticl nanofil copolym nanocomposit poli ethylen co vinyl acet pevac copolym endow high elast resili properti potenti util various applic howev tensil strength copolym insuffici use certain applic requir enough strength toler high extern tension stress studi dolomit propos ... | D053761;D053758 | T073 |
36,293,466 | polysiloxan base polyurethan high strength recycl polysiloxan attract consider attent biomed engin owe inher properti includ good flexibl biocompat howev low mechan strength limit applic scope studi synthes polysiloxan base polyurethan chemic copolymer seri thermoplast polysiloxan polyurethan si tpus synthes use hydrox... | D011140;D012833 | T122;T109 |
36,293,465 | role igl preserv solut rat liver scs hope scarciti liver transplant rise new strategi extend donor pool explor one solut use margin graft extend criteria donor present exampl liver steatosi current preserv solut uw htk igl main design static cold storag scs igl modifi version igl develop suitabl scs dynam preserv hypot... | D019188;D024243;D005234 | T123;T122;T116;T047 |
36,293,464 | stimul mitochondri biogenesi deoxyribonucleosid increas function capac ech defici cell lack effect treatment mitochondri diseas seen develop new approach includ stimul mitochondri biogenesi boost atp product examin effect deoxyribonucleosid dns mitochondri biogenesi function short chain enoyl coa hydratas ech knockout ... | D001678;D004746 | T070;T126;T116;T043 |
36,293,463 | extract character platelet inhibitori effect two polysaccharid cs fungus cardiovascular diseas associ platelet hyperact downregul platelet activ one promis antithrombot strategi studi newli extract two polysaccharid purifi exopolysaccharid epsp purifi intercellular exopolysaccharid ipsp cordycep sinensi cs myceli ferme... | D002318;D032661;D013927 | T047;T046;T004 |
36,293,462 | competit sperm mark beetl monitor approach genet biocontrol studi reproduct biolog sperm mark provid key tool reproduct biolog studi also repres valuabl monitor tool genet pest control strategi steril insect techniqu sperm mark line generat introduc transgen mediat express fluoresc protein spermatogenesi homozyg line e... | D001517;D014231 | T204 |
36,293,461 | role emasr ethanol metabol acinetobact baumannii acinetobact baumannii well known nosocomi pathogen surviv differ environ use intric network regul gene express two compon system tcs form import part regulatori network studi describ identif character novel emasr tcs baumannii construct tn tag mutagenesi librari ema sens... | D040981 | T007 |
36,293,460 | electrochem activ cnt sheet cathod zn co batteri high demand electrochem storag devic increas need high perform batteri zn co batteri offer promis solut co reduct well energi storag applic studi zn co batteri fabric use carbon nanotub cnt sheet cathod zn plate anod electrochem activ techniqu use increas surfac area cnt... | D037742 | T104;T073 |
36,293,459 | flavonoid antidiabet anti inflammatori agent review structur activ relationship base studi meta analysi flavonoid group natur occur polyphenol secondari metabolit report demonstr wide rang pharmacolog properti import antidiabet anti inflammatori effect relationship hyperglycaemia inflamm vascular complic diabet well es... | D005419;D006943 | T121;T127;T109;T033;T047 |
36,293,458 | non tradit pro inflammatori pro atherosclerot risk factor relat system lupus erythematosus cardiovascular diseas cvd one lead caus high mortal patient system lupus erythematosus sle framingham risk score tradit risk factor fulli reflect cvd risk sle patient therefor order stratifi high risk patient addit biomark subcli... | D050197;D008180;D002318 | T047;T046 |
36,293,457 | mitochondri dysfunct neurodegen disord role nutrit supplement mitochondri dysfunct implic pathogenesi number neurodegen disord includ parkinson diseas alzheim diseas amyotroph later sclerosi multisystem atrophi progress supranuclear palsi articl concern specif mitochondri dysfunct defin reduc capac atp product role dep... | D008063;D019578 | T121;T046;T127;T109 |
36,293,456 | explor absorpt mechan imidazolium base ionic liquid epigallocatechin gallat imidazolium base ionic liquid wild use natur product adsorpt purif work one typic polymer ionic liquid pil synthes use l prolin anion exhibit excel adsorpt capac toward tea polyphenol epigallocatechin gallat egcg adsorpt condit optim respons su... | D052578;D001688 | T120;T123;T121;T103 |
36,293,455 | identif candid gene regulatori competit endogen rna cerna network under intramuscular fat content yorkshir pig extrem fat deposit phenotyp intramuscular fat imf content vital pork qualiti serv import role econom perform pig industri non code rnas mrnas involv imf deposit howev function regulatori mechan porcin imf rema... | D062085;D035683 | T123;T114 |
36,293,454 | singl cell dna methyl analysi chicken lampbrush chromosom dna methyl essenti epigenet regul mechan implic transcript replic control development reprogram retroel silenc genom process mammalian develop specif dna methyl pattern establish germ cell allow embryon develop less known germ cell dna methyl speci close gap per... | D019175;D044127 | T045;T044 |
36,293,453 | filament hemagglutinin bordetella pertussi interact integrin cdbcd pertussi agent bordetella pertussi produc number virul factor filament hemagglutinin fhab play role b pertussi adhes epitheli phagocyt cell moreov fhab recent found play crucial role nasal caviti infect b pertussi transmiss new host kda fhab protein tra... | D001886;D014917 | T047;T007 |
36,293,452 | comput model imag intracellular oxygen gradient comput model provid mechanist quantit framework describ intracellular spatial heterogen solut oxygen partial pressur po studi develop evalu finit element model oxygen consum mitochondri bioenerget use comsol multiphys program model deriv steadi state oxygen distribut fick... | D010100;D010101 | T201;T123;T196;T121 |
36,293,451 | anti citrullin peptid antibodi control oral porphyromona aggregatibact speci patient rheumatoid arthriti oral microbiom chang take place initi rheumatoid arthriti ra howev question remain regard oral microbiom pre ra stage individu clinic suspect arthralgia csa two cross section cohort select includ tatarstan women ear... | D000075422;D001172 | T129;T047;T116 |
36,293,450 | asprosin paraventricular nucleus induc sympathet activ pressor respons via camp depend ros product asprosin newli discov adipokin involv regul metabol sympathet overact contribut pathogenesi sever cardiovascular diseas paraventricular nucleus pvn hypothalamus play crucial role regul sympathet outflow blood pressur stud... | D010286;D013481 | T121;T023;T109 |
36,293,449 | insulin diminish superoxid increas cytosol mitochondria cultur cortic neuron treat toxic glutam glutam excitotox involv pathogenesi mani disord includ stroke traumat brain injuri alzheim diseas central insulin resist comorbid condit neurotox glutam glu primarili associ hyperactiv ionotrop n methyl aspart receptor nmdar... | D018698;D013481 | T123;T121;T116;T109 |
36,293,448 | phenol polyaromat hydrocarbon stronger driver host plant speci shape arbuscular mycorrhiz fungal compon mycorrhizospher chang soil microbi communiti respons hydrocarbon pollut critic indic disturb ecosystem condit core compon communiti function adjust life histori trait host environment factor consist arbuscular mycorr... | D038821;D055137;D011084;D064307 | T032;T109;T004;T028;T001 |
36,293,447 | ectop express hbrpw hevea brasiliensi improv arabidopsi thaliana resist powderi mildew fungi erysiph cichoracearum ucsc rpws resist powderi mildew atyp broad spectrum resist gene provid resist powderi mildew fungi powderi mildew rubber tree one serious fungal diseas affect tree growth latex product howev rpw homolog ru... | D017360;D028482;D029681;D001203 | T004;T116;T002 |
36,293,446 | import micromilieu pathophysiolog mineralocorticoid receptor activ mineralocorticoid receptor resid wrong neighborhood mineralocorticoid receptor mr member steroid receptor famili act ligand depend transcript factor addit classic effect water electrolyt balanc involv pathogenesi cardiovascular renal diseas subject rese... | D018161;D000450 | T121;T116;T109;T192;T125 |
36,293,445 | crystal structur cypa complex fluorol identifi substrat access channel high affin ligand bind site cytochrom p cypa major human drug metabol enzym notori known extrem substrat promiscu alloster behavior implic drug drug interact despit extens investig mechan ligand bind cypa fulli understood determin crystal structur c... | D051544;D005456 | T130;T126;T116 |
36,293,444 | activ mening affer relev trigemin headach pain photothrombot stroke lesion pilot studi mice stroke follow immedi sever headach headach initi activ trigemin mening affer assess chang activ mening affer mice subject cortic photothrombosi cortic photothrombosi induc ipsilater lesion variabl size associ contralater sensori... | D050051;D020521 | T123;T047;T116 |
36,293,443 | synthesi anticanc antitubercular properti new chalcon nitrogen contain five member heterocycl hybrid bear sulfonamid moieti new seri sulfonamid b b synthes n sulfon reaction sulfonyl chlorid b five new seri chalcon sulfonamid hybrid f prepar via claisen schmidt condens newli obtain sulfonamid aromat aldehyd f basic med... | D047188;D002599;D000970 | T121;T109 |
36,293,442 | rational combin bcl inhibitor venetoclax pik inhibitor bimiralisib treatment idh flt mutat acut myeloid leukemia octob fda grant regular approv venetoclax abt combin hypomethyl agent newli diagnos acut myeloid leukemia aml adult year older patient comorbid preclud intens chemotherapi treatment respons venetoclax combin... | D015470;D000970 | T121;T191;T109 |
36,293,441 | downregul pcbp associ factor protect vascular age via nrf signal pathway activ increas evid shown vascular age key role pathogenesi vascular diseas pcbp associ factor pcaf involv mani vascular patholog process role pcaf vascular age unknown studi aim explor role under mechan pcaf vascular age result demonstr express pc... | D051267;D000804 | T123;T121;T116 |
36,293,440 | contribut jak haplotyp predisposit myeloprolif neoplasm haplotyp ggcc consist set genet variat distribut along chromosom p extend janus kinas gene insulin like mark four joint inherit variant rs rs rs rs haplotyp strong associ develop bcr abl negat myeloprolif neoplasm mpns preced acquisit jakvf variant common genet al... | D009196;D009369;D061385 | T121;T191 |
36,293,439 | regul molecular target osteosarcoma treatment preval malign bone tumor osteosarcoma affect growth plate long bone adolesc young adult standard chemotherapeut method show poor respons rate patient recurr metastat phase therefor critic develop novel effici target therapi address relaps case regard rna interfer technolog ... | D012516;D001859;D035683 | T123;T191;T114 |
36,293,438 | cellular molecular mechan ozon therapi present knowledg prospect applic complementari adjuv palliat cure ozon therapi increas use global wide varieti diseas | D010126 | T103 |
36,293,437 | lipid droplet particip zika virus infect lipid droplet lds high conserv dynam intracellular organell function limit serv neutral lipid reservoir also particip non energi storag function cell lipid metabol protect cell stress maintain protein homeostasi regul nuclear function zika virus zikv infect virus hijack lds prov... | D000071244;D000071243 | T005;T047 |
36,293,436 | ser plsr analysi vagin microflora toward spectral librari microorgan accur identif microorgan belong vagin microflora crucial establish microorgan respons microbi shift benefici symbiot pathogen bacteria understand pathogenesi lead vaginosi vagin infect studi involv surfac enhanc raman spectroscopi ser techniqu compil ... | D064307;D016585 | T001;T047;T032;T028 |
36,293,435 | cell compon function tumor microenviron thyroid cancer thyroid cancer common cancer endocrin system thyroid cancer good prognosi resist treatment show aggress behavior like tumor thyroid cancer harbor tumor microenviron tme compos cancer associ fibroblast caf immun cell autoimmun lymphocyt thyroid occur thyroid may ass... | D013964;D000072645 | T191;T025 |
36,293,434 | radic peroxid produc f type ferryl form bovin cytochrom c oxidas reduct respiratori cytochrom c oxidas cco associ generat transmembran proton gradient two mechan one proton pump two differ type ferryl intermedi catalyt heme cu b center p f form particip equival ferryl state also form reaction oxid cco h interest acid s... | D003576;D010545 | T197;T126;T116 |
36,293,433 | one step carbon synthesi magnet biochar network structur applic organ pollut control studi magnet biochar uniqu network structur synthes use simpl control method brief microbi filament fungus trichoderma reesei use templat fe ad cultur process result uniform recombin bio assembl properti fungal hypha final magnet bioch... | D004785;D014874 | T131 |
36,293,432 | structur interact molecular fibrillar collagen type fibronectin role regul mesenchym stem cell morpholog function activ observ differ structur nativ tissu tissu form vitro caus loss function activ cell cultur vitro lack fundament knowledg protein mechan interact limit abil effect creat vitro nativ tissu collagen abl sp... | D005353;D059630 | T123;T116;T025 |
36,293,431 | dysregul hemostasi immunothrombosi cerebr cavern malform cerebr cavern malform ccm neurovascular diseas affect general popul long time ccm research focus genet mutat endotheli junction prolifer recent transcriptom proteom studi reveal hemostat system neuroinflamm play crucial role develop sever cavernoma public come gr... | D020786;D006490 | T121;T019;T191 |
36,293,430 | relationship inflamm age relat neurocognit chang relationship inflamm age relat neurocognit chang signific may relat age relat immun dysfunct character senesc immun cell elev inflammatori marker peripher circul central nervous system review discuss potenti mechan includ develop vascular inflamm neuroinflamm organell dy... | D007249;D019965 | T046;T048 |
36,293,429 | whole exom sequenc silico analysi human sertoli patient non obstruct azoospermia non obstruct azoospermia noa serious caus male infertil sertoli cell respond androgen take role support spermatogenesi may caus infertil work aim enhanc genet diagnosi noa via discoveri new hub gene implic human noa better assess odd succe... | D053713 | T047 |
36,293,428 | molecular mechan liver fibrosi potenti therapi applic liver fibrosi result repeat persist liver damag start hepatocyt injuri advanc inflamm recruit activ addit liver immun cell lead activ hepat stellat cell hscs primari sourc myofibroblast mfs result collagen synthesi extracellular matrix protein accumul although fda e... | D008103;D008107 | T033;T047 |
36,293,427 | begin meiosi mammalian femal germ cell never end stori intrins extrins factor meiosi uniqu divis germ cell result recombin matern patern genom product haploid gamet mammal begin fetal life femal puberti male case enter meiosi requir time switch mitot meiotic cell cycl transit potenti pluripot status meiotic differenti ... | D008540;D039904 | T025;T043 |
36,293,426 | studi detect oleuropein extra virgin oliv oil use enzymat biosensor oleuropein oleu import indic qualiti authent extra virgin oliv oil evoo electrochem sensor biosensor detect oleuropein use test adulter extra virgin oliv oil present studi aim qualit quantit determin oleuropein commerci evoo sampl appli electrochem tec... | D037742;D015374 | T104;T059;T073;T075 |
36,293,425 | identif novel de novo variant casz caus rare type dilat cardiomyopathi new de novo frameshift variant identifi casz gene lead sever dilat cardiomyopathi | D002311 | T047 |
36,293,424 | legumain activ control extend activ site residu substrat conform legumain lysosom cystein proteas strict specif cleav asparagin residu sequenc comparison legumain belong merop clan cd cystein proteas indic structur mechanist relat caspas contrast caspas legumain harbor ph depend ligas activ addit proteas activ although... | D001216;D020169 | T123;T126;T116 |
36,293,423 | comprehens compar analysi develop molecular marker dianthus speci base complet chloroplast genom sequenc dianthus spp genus high econom ornament valu caryophyllacea includ famous fresh cut carnat tradit chines herbal medicin superbus despit dianthus speci seen everywher daili live genom inform phylogenet relationship r... | D054628;D029749;D004365 | T121;T123;T002;T028 |
36,293,422 | identif kfb famili moso bamboo reveal potenti function pekfb involv stress respons lignin polymer kelch repeat f box kfb protein import e ubiquitin ligas demonstr perform import post translat regulatori role plant mediat multipl biolog process despit import kfbs yet identifi character bamboo studi pekfb identifi f box ... | D008031;D018506 | T045;T123;T109 |
36,293,421 | evalu proteom lipidom chang aeromona infect trout kidney tissu use ft ir spectroscopi maldi mass spectrometri imag aeromona speci opportunist bacteria caus vast spectrum human diseas includ skin soft tissu infect mening endocard periton gastroenter final hemorrhag septicemia aim research indic molecular alter protein l... | D000081362;D000333 | T007;T091;T109 |
36,293,420 | synthesi anticanc antivir activ c branch arabinonucleosid arabinofuranosyl pyrimidin purin nucleosid analogu contain alkylthio acetylthio thiosugar substitu c posit prepar correspond silylen acet protect nucleosid exomethylen photoiniti radic mediat hydrothiol reaction although stereochem outcom hydrothiol depend struc... | D054330;D000086382;D011741 | T047;T114;T067;T109 |
36,293,419 | bergamottin pap induc ace degrad allevi infect sar cov angiotensin convert enzym ace function receptor sar cov appear like mediat ncov entri human cell howev inhibitor pap bergamottin discov preferenti bind ace prevent rbd spike protein bind ace reduc bind site rbd spike protein addit investig bind energi pap bergamott... | D000086382;D011564 | T121;T047;T067;T109 |
36,293,418 | correl phenotyp genotyp ctnnb syndrom systemat review literatur ctnnb syndrom rare neurodevelopment disord associ development delay intellectu disabl delay absent speech aim present studi systemat review avail data preval clinic manifest evalu correl phenotyp genotyp publish case patient ctnnb syndrom studi identifi sy... | D008607;D005124 | T019;T048 |
36,293,417 | composit structur modif ion beam graphen oxid radiat detect studi present studi graphen oxid foil thick irradi vacuum use charg state one charg state ion proton helium oxygen ion energi mev fluenc ioncm ioncm structur chang generat ion energi deposit investig x ray diffract suggest generat new phase reduc go go quantum... | D011522;D037742 | T104;T196;T073 |
36,293,416 | clean label cure meat effect replac nitratesnitrit nutrient bioaccess peptid format cellular toxic vitro digest salami cure salt compos mixtur nitrat nitrit preserv wide use process meat despit mani desir technolog effect use meat product link methemoglobinemia format nitrosamin therefor increas anti nitrit feel grown ... | D008461;D009602 | T168;T131;T109 |
36,293,415 | graphen quantum dot modifi upconvers nanoparticl photodynam therapi photodynam therapi pdt novel techniqu extens employ cancer treatment util reactiv oxygen speci ros kill malign cell howev photosensit pss short ros yield affect therapeut effect pdt thus substanti demand develop novel pss pdt advanc clinic translat stu... | D010778;D006108;D045663;D053758 | T061;T196;T073;T109 |
36,293,414 | discoveri new phenylaceton monooxygenas variant develop substitut indigoid biocatalysi indigoid natur pigment obtain plant ancient cultur roman use main dye wherea asian cultur appli compound treatment agent sever diseas modern era chemic industri made possibl identifi develop synthet rout obtain petroleum deriv howev ... | D006899;D010578 | T126;T116;T109 |
36,293,413 | improv fmoc solid phase synthesi human beta defensin human defensin hbd residu antimicrobi immunomodulatori peptid play multipl role host defens system addit interact cell membran hbd also ligand melanocortin receptor cytokin receptor voltag gate potassium channel structur function studi hbd hamper ineffici synthet rec... | D023083;D024642 | T123;T116 |
36,293,412 | cytotox cell express leukocyt associ immunoglobulin like receptor lair viral hepat c mediat hepatocellular carcinoma virus relat hepatocellular carcinoma hcc pathogenesi involv liver inflamm therefor despit success treatment hepat c virus hcv may progress hcc initi liver cirrhosi cytotox cell tcs known involv hcv relat... | D006528;D008113;D006526;D019698 | T047;T191 |
36,293,411 | relationship neurogli apoptosi neuroinflamm epilept focus brain blood patient drug resist epilepsi neurogli apoptosi neuroinflamm play import role epileptogenesi aim studi evalu neuron glial apoptosi associ neuroinflamm brain epilept focus inflammatori chang blood patient focal drug resist epilepsi dre patholog chang t... | D004827;D000069279 | T033;T047 |
36,293,410 | physiolog base pharmacokinet model nanoparticl biodistribut review exist model simul softwar data analysi tool cancer treatment pharmaceut develop requir target treatment less toxic therapeut intervent achiev real progress diseas scenario nanomedicin emerg reliabl tool improv drug pharmacokinet translat clinic biolog b... | D053758;D009369;D001688 | T121;T123;T191;T073 |
36,293,409 | effect exercis train mitochondri function cardiovascular diseas systemat review meta analysi mitochondria dysfunct implic pathogenesi cardiovascular diseas cvd exercis train potenti effect non pharmacolog strategi restor mitochondri health cvd howev exercis modifi mitochondri function inconclus conduct systemat review ... | D000975;D002318 | T123;T121;T039;T044;T047 |
36,293,408 | exogen nitric oxid allevi damag caus tomato yellow leaf curl virus tomato regul peptidas inhibitor gene tomato yellow leaf curl virus tylcv causal agent one sever diseas affect tomato growth howev nitric oxid mediat plant resist studi investig molecular mechan exogen donor mediat diseas resist tomato seedl tomato seedl... | D018551;D053839 | T168;T005;T002 |
36,293,407 | genom wide identif agc protein kinas gene famili relat photosynthesi rice oryza sativa camp depend protein kinas cgmp depend protein kinas g phospholipid depend protein kinas c agc perform various function plant involv growth immun apoptosi stress respons agc gene famili well describ arabidopsi howev limit inform provi... | D012275 | T168;T002 |
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