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36,286,528
imag inflammasom activ microglia inflammasom multiprotein complex play key role host innat immun respons insult assembl inflammatori complex initi oligomer upstream inflammasom form sensor follow well orchestr multi step process lead downstream effector function critic innat immun respons final assembl step provid dete...
D058847;D053468
T123;T116
36,286,506
experi middl age older taiwanes adult chronic insomnia descript qualit studi purpos current studi describ experi middl age older adult chronic insomnia descript qualit studi design use semi structur interview conduct particip two primari clinic health center northern taiwan mean age particip year particip middl age age...
D007319
T184;T047;T048
36,286,505
standard posit physic approach improv oral hygien nurs home resid alzheim diseas relat dementia resid alzheim diseas relat dementia adrd nurs home nhs reli direct care worker dcws assist activ daili live oral hygien current qualiti improv project implement evalu effect teach standard posit physic approach oral hygien c...
D000544;D005851
T047;T091;T048
36,286,504
educ polici advocaci predict use hospit order skill nurs facil nurs social worker uniqu posit advoc patient wish hospit dnh direct purpos current studi explor impact dnh educ polici advocaci use dnh order nurs rns licens practic nurs lpns social worker employ skill nurs facil snfs multisit secondari analysi use cross s...
D012866;D057766
T170;T073;T093
36,286,503
feasibl physic train intervent music communiti dwell older women quasi experiment studi physic activ perform music activ import brain area associ cognit emot motor skill limit inform avail feasibl accept physic activ music intervent current studi aim determin feasibl physic train intervent music older women b describ d...
D057187;D009146
T056;T170
36,286,502
continu commit long term care rns experi communic resid famili end life care prefer rns lead care plan long term care ltc yet knowledg gap regard communic resid famili end life eol care prefer sampl ltc rns virtual interview describ eol care communic experi use interpret phenomenolog framework narrat analysi within int...
D013727;D017051;D005851
T058;T091;T093
36,286,501
older adult famili caregiv perspect engag primari care purpos current depth qualit studi explor experi older adult famili caregiv primari care twenti patient caregiv six comprehens primari care plus cpc practic patient famili advisori council within larg academ health system particip telephon interview decemb may parti...
D017028;D012648
T099;T098;T097;T056
36,286,484
nonlyt quasi envelop hepatovirus releas facilit px protein interact e ubiquitin ligas itch hepatovirus atyp hepatotrop picornavirus releas infect cell without lysi small membran vesicl exosom like quasi envelop virion ehav infecti form hepat virus hav found circul blood acut infect ehav releas multivesicular endosom pr...
D044767;D030041
T005;T126;T116
36,286,483
epstein barr virus viral process factor ea facilit virus lytic replic induc poli adp ribos polymeras degrad gammaherpesvirus includ epstein barr virus ebv import human pathogen associ various tumor poli adp ribos polymeras parp multifunct host nuclear protein respons poli adp ribosyl ation paryl target protein parp act...
D004854;D020031
T005;T047
36,286,482
cellular heterogen molecular reprogram host respons influenza acut lung injuri exuber host respons contribut influenza virus iav influenza mediat lung injuri howev despit signific inform host respons iav cellular framework molecular interact dictat develop acut injuri iav infect lung remain incomplet understood perform...
D007251;D009976;D009980;D055371
T047;T005;T037
36,286,481
block autophagi macrophag enhanc virus replic eye diseas ocular infect transgen mice macrophag one first innat immun infiltr cornea mice follow ocular infect herp simplex virus hsv use gamma interferon ifn interleukin il inject polar macrophag respect condit knockout mice shown macrophag play import role suppress virus...
D018259;D006561;D005128
T005;T047
36,286,478
integr exogen tune thraustochytrid ferment sulfur polymer singl cell oil develop plant like oil studi demonstr bioprocess approach encompass exogen addit low molecular weight compound tune fatti acid fa profil novel thraustochytrid strain produc desir fas maximum lipid recoveri dri wt biomass obtain tween mgl vitamin b...
D011136;D005227
T121;T123;T109;T168;T122
36,286,477
marin biolog macromolecul chemic modifi macromolecul potenti anticoagul coagul potenti defens mechan involv activ seri zymogen convert solubl fibrinogen insolubl fibrin clot prevent bleed hemorrhag complic prevent extra format diffus clot counterbal inhibitori mechan activ level coagul pathway contrariwis system evad n...
D000925;D013927
T121;T046
36,286,476
branch chondroitin sulfat oligosaccharid deriv sea cucumb acaudina molpadioid stimul neurit outgrowth fucosyl chondroitin sulfat fcs sea cucumb acaudina molpadioid fcs first one report branch disaccharid galnac fuc ss sulfat fuc four size homogen fraction seven oligosaccharid separ elimin depolymer product detail nmr s...
D012616
T204
36,286,475
bromoditerpen red seawe sphaerococcus coronopifolius potenti cytotox agent proteasom inhibitor relat mechan action seawe great sourc compound cytotox properti potenti use anticanc agent studi evalu cytotox proteasom inhibitori activ r hydroxi bromosphaerol hydroxi bromosphaerol bromosphaerol isol sphaerococcus coronopi...
D012624;D009447;D000461;D000970
T121;T109;T191;T204;T002
36,286,474
antimicrobi peptid lj hep lateolabrax japonicus exert activ multipl pathogen bacteria immun protect vivo hepcidin wide present mani kind fish import innat immun factor varieti hamp type hepcidin strong antimicrobi activ immunomodulatori function expect develop substitut antibiot studi antimicrobi activ hepc japanes sea...
D064451;D009990
T125;T123;T116;T013
36,286,473
structur investig aaptourinamin novel modul assembl base calcul natur product various complic structur still challeng elucid compound especi lack two dimension nuclear magnet reson nmr correl main caus high ch ratio proton defici multipl heteroatom convent structur analyt method report novel modul assembl calcul method...
D011161;D000470;D001688
T123;T121;T109;T131;T204
36,286,472
two laminaria japonica ferment broth allevi oxid stress inflammatori respons caus uvb damag photoprotect repar effect uvb radiat induc oxid stress inflammatori respons human epiderm cell establish uvb induc damag model human immort epiderm keratinocyt hacat explor protect repar effect laminaria japonica uvb damag epide...
D007795;D014920
T121;T168;T204
36,286,471
meridianin inhibit gsk vivo improv behavior alter induc chronic stress major depress disord mdd sever mental alter multifactori origin chronic stress one relev environment risk factor associ mdd although exist therapeut option patient still resist type treatment gsk inhibitor consid promis therapeut tool counteract str...
D006624;D051057
T026;T023;T126;T116
36,286,470
manzamin alter vitro calvari osteoblast function manzamin marin deriv alkaloid anti viral anti prolif properti current investig efficaci treatment certain virus malaria herp hiv cancer breast cervic colorect manzamin found exert effect via modul six gene express gene critic craniofaci develop via wnt notch pikakt pathw...
D019869;D051057
T126;T116
36,286,469
prepar anticoagul antioxid properti glucosamin heparin salt excess inorgan ion vivo may lead electrolyt disord induc damag human bodi therefor prepar enhanc bioactiv compound compos activ organ cation organ anion great interest among research work glucosamin heparin salt ghs primarili synthes posit charg glucosamin hyd...
D006493;D000925
T123;T121;T109
36,286,468
astaxanthin protect neuron excitotox via glutam receptor inhibit improv mitochondri function excitotox known associ neurodegen diseas alzheim diseas parkinson diseas amyotroph later sclerosi huntington diseas well age stroke trauma ischemia epilepsi excess releas glutam overactiv glutam receptor calcium overload mitoch...
D018698;D019636
T123;T047;T121;T116
36,286,467
exogen arachidon acid affect fucoxanthin biosynthesi photoprotect phaeodactylum tricornutum fucoxanthin oxygen carotenoid compon report play import role anti oxid anti obes anti cancer human bodi fucoxanthin chlorophyl protein fcp complex particip light harvest photoprotect diatom order better understand chang fucoxant...
D017377
T204
36,286,466
antimicrobi secondari metabolit mangrov plant asia pacif microb white spot syndrom virus account sever loss shrimp farm industri global review examin literatur mangrov plant asia pacif antibacteri antifung antivir activ avail data publish subject collect googl scholar pubm scienc direct web scienc chemspid pubchem libr...
D000935;D001688
T121;T195;T123
36,286,465
tetrahydrofuran motif marin lipid terpen heterocycl particular common moieti within marin natur product specif tetrahydrofuranyl ring present varieti compound present complex structur interest biolog activ focus terpenoid high number tetrahydrofuran contain metabolit isol last decad show promis biolog activ make potent...
D001688;D000970
T123;T121;T109
36,286,464
new ceramid cerebrosid deep sea far eastern starfish ceramast patagonicus three new ceramid three new cerebrosid along three previous known cerebrosid ophidiocerebrosid c ce isol deep sea starfish speci orang cooki starfish ceramast patagonicus structur amp nbsp determin nmr esim techniqu also chemic transform ceramid ...
D002554;D002518
T121;T123;T109
36,286,463
toward sustain medicin resourc marin soft coral aquacultur insight chemic divers biolog potenti recent decad aquacultur techniqu soft coral made remark progress term condit product research abl obtain larger quantiti soft coral thus larger quantiti biolog activ metabolit allow studi biolog activ mani pharmacolog assay ...
D037421;D004224
T204;T109
36,286,462
anti inflammatori antioxid properti malapterurus electricus skin fish methanol extract arthrit rat therapeut protect effect protect therapeut anti inflammatori antioxid potenc malapterurus electricus f malapterurida skin fish methanol extract fe mgkgbwtday day oral test monosodium urat msu induc arthrit wistar albino m...
D000975;D014527
T123;T121;T109;T114;T039;T044
36,286,461
fucoidan brown alga comparison sulfat polysaccharid fucus vesiculosus ascophyllum nodosum prepar sulfat polysaccharid obtain brown alga known fucoidan biopolym attract consider attent due mani biolog activ may find practic applic two atlant repres phaeophycea name fucus vesiculosus ascophyllum nodosum belong order fuca...
D044646;D044645;D000459
T002;T204
36,286,460
aminopyrimidon aminoimidazol alkaloid rodrigu calcar marin spong ernsta naturali chemic studi ch cl meoh extract spong ernsta naturali collect rodrigu mauritius base molecular network derepl strategi highlight one novel aminopyrimidon alkaloid compound ernstin seven new aminoimidazol alkaloid compound phorbatopsin e ca...
D011161;D000470
T123;T121;T109;T131;T204
36,286,459
isol synthesi absolut configur pericharaxin b epimer hydroxi polyen glycerol ether calcarean spong pericharax heteroraphi natur occur epimer hydroxi polyen glycerol ether pericharaxin b b isol calcarean spong pericharax heteroraphi structur stereochem character diastereoisom establish basi spectroscop data analysi tota...
D011161;D001688
T123;T121;T204
36,286,458
marin biotoxin whole process scallop argentin sea harm algal bloom increas worldwid threat seafood industri human health consequ natur product biotoxin accumul shellfish argentin sea identifi issu offshor fisheri patagonian scallop zygochlami patagonica lead potenti harm effect consum assess spatial tempor pattern mari...
D008387;D049897
T131;T116;T204
36,286,457
vivo studi evalu efficaci blue shark prionac glauca cartilag collagen cosmet blue shark prionac glauca class chondrichthy pelag shark speci common found tropic temper ocean shark main sold asian countri food tradit chines medicin accord red list intern union conserv natur p glauca classifi low risk near endang p glauca...
D000068937;D003358;D012754
T073;T167;T013
36,286,456
total synthesi biolog evalu modifi ilamycin deriv ilamycinsrufomycin marin cycloheptapeptid contain unusu amino acid produc streptomyc sp compound show potent activ rang mycobacteria includ multidrug resist strain mycobacterium tuberculosi cyclic peptid target aaa protein clpc togeth peptidas clppclpp form essenti atp ...
D001426;D009169
T123;T007;T116
36,286,455
vivo anticoagul antithromb activ depolymer glycosaminoglycan apostichopus japonicus dynam effect exposur relationship rat plasma glycosaminoglycan apostichopus japonicus ahg depolymer fragment dahg anticoagul fucosyl chondroitin sulfat aim studi evalu anticoagul antithromb activ ahg dahg well reveal dynam relationship ...
D000925;D047528
T121;T204
36,286,454
molecular network guid catalog secondari metabolom select egyptian red sea soft coral soft coral recogn abund sourc divers secondari metabolit uniqu chemic featur physiolog capabl howev discoveri metabolit usual hinder tradit protocol requir larg quantiti live tissu isol spectroscop investig order overcom problem untar...
D037421;D004224;D012717;D061065
T121;T204;T109
36,286,453
compar studi anti obes effect dietari sea cucumb saponin energi restrict respons weight loss weight regain mice dietari supplement sea cucumb saponin calori restrict prove effect allevi obes differ anti obes effect sea cucumb saponin energi restrict weight loss weight regain still unknown present studi high fat induc o...
D012616;D012503
T204;T109
36,286,452
network pharmacolog analysi red sea spong hyrtio erectus extract reveal anticanc efficaci correspond load niosom studi lc hrms assist chemic profil hyrtio erectus spong led annot eleven major compound h erectus deriv crude extract test vitro antiprolif activ three human cancer cell line hep g human liver cancer cell li...
D000970;D008081
T121;T109
36,286,451
therapeut potenti microalga deriv bioactiv metabolit influenc differ larg scale cultur strategi microalga identifi one promis sourc novel bioactiv compound biomed applic food industri cosmet last decad sever biotechnolog develop facilit identif grow number compound well studi optim microalga cultur condit product bioma...
D058086;D044665
T002;T204
36,286,450
bioactiv peptid skipjack tuna cardiac arteri bulb prepar identif antioxid activ stabil thermal ph simul gastrointestin digest treatment cardiac arteri bulb skipjack tuna katsuwonus pelami rich elastin hydrolys high qualiti raw materi daili cosmet order effect util skipjack tuna process byproduct cardiac arteri bulb pre...
D000975;D011492
T123;T121;T116;T039;T044
36,286,449
marin compound mitochondria malign therapeut nexus marin environ import yet general underexplor contain new sourc function constitu affect various pathway food process storag fortif bioactiv secondari metabolit produc marin microorgan may signific potenti applic human various compon isol dispar marin microorgan includ ...
D000970;D009369;D001688
T121;T191;T123;T109
36,286,448
new perspect reveal algicid properti bacillus subtili alexandrium pacificum bacteri communiti toxin algicid bacteria import control toxic dinoflagel bloom studi environment behavior relat algal toxin still lack studi bacillus subtili show highest algicid activ alexandrium pacificum group iv six bacillus strain treat v ...
D004141;D020591;D014118
T123;T007;T131;T204
36,286,447
growth factor free vascular marin origin collagen spong use cryopreserv stromal vascular fraction human adipos tissu success integr transplant three dimension tissu engin te construct depend great rapid vascular therefor essenti address vascular issu initi design construct perfus tissu two import variabl regard scaffol...
D000090002;D000273
T201;T024;T031
36,286,446
intratympan administr dieckol prevent ototox hear loss system administr dieckol report amelior acut hear loss studi dieckol deliv inner ear intratympan rout function anatom effect safeti dieckol assess use rat ototox model
D002945;D034381
T033;T121;T197;T047
36,286,445
nitrogen starvat enhanc product satur unsatur fatti acid aurantiochytrium sp pku sw regul key biosynthet gene nitrogen depriv known improv lipid accumul microalga thraustochytrid howev pattern fatti acid product molecular mechan under accumul unsatur satur fatti acid sfas nitrogen starvat remain larg unknown thraustoch...
D009584;D058009
T123;T196;T204
36,286,444
seven new alkaloid isol marin flavobacterium tenacibaculum discolor sv marin flavobacterium tenacibaculum discolor sv proven promis produc bioactiv nitrogen contain heterocycl chemic investig amp nbsp discolor sv reveal seven new heterocycl includ six new imidazolium contain alkaloid discolin c h one pyridinium contain...
D000470;D000890;D002262
T123;T121;T116;T109;T131;T126
36,286,443
investig genotox potenti marin toxin c samt use vivo comet micronucleus assay contamin respons atyp toxic report mussel bizert lagoon northern tunisia last decad character c sphinganin analog mycotoxin c samt neurotoxin show common mous toxic symptom includ flaccid paralysi sever dyspnea follow rapid death hazard asses...
D009183
T131;T109
36,286,442
carotenoid marin microalga antimelanoma agent melanoma cell high invas metastat tumor cell common express molecular alter contribut multidrug resist eg braf mutat convent treatment effect long term requir exhaust search new altern recent carotenoid microalga investig adjuv antimelanoma therapi due safeti accept clinic ...
D058086;D008545;D000970
T121;T191;T204;T109
36,286,441
epigenet manipul induc product immunosuppress chromon cytochalasin mangrov endophyt fungus phomopsi asparagi dhs mangrov endophyt fungus phomopsi asparagi dhs found particular product regard accumul substanti new compound previous studi order explor potenti produc unobserv secondari metabolit epigenet manipul use fungu...
D003572;D002867
T123;T121;T109
36,286,440
bacteria associ benthic invertebr extrem marin environ promis underexplor sourc biotechnolog relev molecul microb invertebr associ common occur natur play fundament role life symbiont even hostil habitat assum key import ecolog evolutionari studi relev biotechnolog extrem environ emerg new frontier natur product chemis...
D007448;D001688
T123;T121;T204
36,286,439
evalu magnesium phosphat particl incorpor co electrospun chitosan elastin membran skin wound heal major challeng face clinician treat burn wound lack integr treatment wound inadequ mechan properti treatment high infect rate ultim lead poor wound resolut electrospun chitosan membran escm gain popular use tissu engin app...
D000890;D002056;D048271;D057139
T121;T073;T037;T109
36,286,438
caspas cathepsin b inhibitor marin invertebr aim reduct neuroinflamm neuroinflamm condit associ sever type dementia alzheim diseas ad main caus inflammatori respons amyloid peptid induc microgli activ subsequ cytokin releas neuron caspas inflammasom cathepsin b key enzym mediat neuroinflamm ad therefor reveal new molec...
D002401;D000544
T047;T126;T116;T048
36,286,437
come new age marin glycom fundament medic ecolog aspect special issu marin glycom https wwwmdpicomjournalmarinedrugsspecialissuesmarineglycom access septemb provid new approachesand inform bioactiv compound glycan lectin marin anim seawe microorgan applic clinic therapi elucid thephysiolog function marin organ
D054794;D037102
T090;T116;T123
36,286,436
vitro modul complement activ therapeut prospect analogu marin polychaeta arenicin peptid widespread resist antibiot pathogen bacteria make develop new generat antimicrobi urgent task develop new antibiot must accompani comprehens studi biolog activ order avoid advers side effect applic promis antibiot prototyp deriv st...
D011077
T204
36,286,435
quinoid pigment sea urchin scaphechinus mirabili strongylocentrotus intermedius biolog activ potenti applic review present literatur data histori discoveri quinoid compound biosynthesi biolog activ special attent paid descript quinoid pigment sea urchin scaphechinus mirabili famili scutellida strongylocentrotus interme...
D047269;D039282;D009285;D061065;D001688
T121;T123;T109;T204;T002
36,286,434
silico analysi bioactiv peptid produc underutil sea cucumb product bioinformat approach bioinformat tool wide use predict potent bioactiv peptid food deriv materi studi focus util sea cucumb process product generat antioxid ace inhibitori peptid applic rang silico techniqu identifi peptid use lc msms virtual screen pep...
D019295;D012616
T091;T204
36,286,433
krill oil inhibit cholesterol synthesi stimul cholesterol excret hypercholesterolem rat present studi aim investig antihypercholesterolem effect krill oil supplement high cholesterol diet induc hypercholesterolem rat mechan under effect rat divid five group normal control control high cholesterol diet krill oil mgkg bw...
D033201;D006937;D006949
T033;T047;T204
36,286,432
depth understand ecklonia stolonifera okamura review bioactiv bioactiv compound ecklonia stolonifera okamura es main distribut coastal area middl pacif around korea japan long stand edibl valu rich various compound polysaccharid fatti acid algin acid fucoxanthin phlorotannin among polyphenol compound phlorotannin main ...
D000975;D000459
T123;T121;T204;T039;T044
36,286,431
nanoformul seawe eisenia bicyc albumin nanoparticl target cardiovascular diseas vitro vivo evalu natur product especi deriv seawe start seen effect various diseas cardiovascular diseas cvds studi aim design novel oral formul bovin albumin serum nanoparticl bsa nps load extract eisenia bicyc valid benefici health effect...
D012624;D002318;D006937;D000459;D053758;D001688
T123;T121;T073;T204;T047
36,286,430
vitro anti inflammatori activ fucoidan five speci brown seawe studi aim compar anti inflammatori effect fucoidan brown seawe saccharina japonica sj fucus vesiculosus fv fucus distichus fd fucus serratus fs ascophyllum nodosum determin relationship composit biolog activ anti inflammatori activ test vitro believ inflamm ...
D000459;D012624;D044645
T002;T204
36,286,429
spong deriv bromin compound aeroplysinin impair endotheli inflammatori respons inhibit nf b pathway aeroplysinin apl bromin compound isol marin spong aplysina aerophoba exhibit pleiotrop bioactiv effect impair cell growth cancer cell inhibit angiogenesi vitro vivo modul redox status differ cell type among report activ ...
D016328;D011161
T129;T116;T204
36,286,428
uncommon capnosan diterpen neuroprotect potenti south china sea soft coral sarcophyton boettgeri first investig south china sea soft coral sarcophyton boettgeri afford five new capnosan diterpen sarboettgerin e togeth one known relat compound pavidolid structur includ absolut configur elucid extens spectroscop analysi ...
D037421;D018696;D004224
T121;T169;T204;T109
36,286,427
scalaran sesterterpenoid isol marin spong hyrtio erectus cytotox eighteen scalaran sesterterpenoid includ eight new deriv isol spong hyrtio erectus famili thorectida extract show cytotox hela mcf cell line new deriv six compound found contain hydroxybutenolid moieti capabl revers stereoinvers hydroxyl carbon center inf...
D011161;D000970
T121;T204;T109
36,286,426
identif character atp bind cassett transport chlamydomona reinhardtii microalga promis microorgan use produc valu ad product develop sustain approach environment remedi atp bind cassett protein abc chlamydomona reinhardtii character indispens transport co concentr mechan lipid biosynthesi heavi metal sequestr howev mic...
D018528;D016825
T123;T116;T204
36,286,425
revalor microalga biomass synergist interact sustain applic bioplast generat microalga cyanobacteria photosynthet microorgan sourc renew biomass use bioplast product microorgan high growth rate contrari feedstock land crop requir arabl land addit use feedstock bioplast product compet food sourc eg corn wheat soy protei...
D058086;D054813;D000458
T007;T204;T109
36,286,424
altern solvent biorefineri spirulina impact pretreat free fatti acid high ad valu grow demand molecul interest microalg biomass phycobiliprotein led accumul unus product exampl phycocyanin obtain extract spirulina generat cake rich non polar molecul interest free fatti acid ffas ffas general consid marker lipidom degra...
D053545;D058086
T007;T204
36,286,423
compar studi docosahexaeno acid differ molecular form promot apoptosi non small cell lung cancer cell ppar depend manner cancer lead caus death worldwid grow evid shown docosahexaeno acid dha amelior effect cancer howev effect dha enrich phosphatidylcholin dha pc efficaci differ dha pc dha triglycerid dha tg dha ethyl ...
D002289;D008175
T191
36,286,422
algin base micro nanosystem target cancer therapi algin wide explor due salient advantag hydrophil biocompat mucoadhes featur bioavail environment benign properti cost effect appli design micro nanosystem control target drug deliveri cancer therapi algin biopolym find usag encapsul anticanc drug improv bioavail sustain...
D000464;D009369
T121;T122;T191;T109
36,286,421
cytotox n methylpretrichodermamid b reveal anticanc activ inhibit p glycoprotein drug resist prostat cancer cell n methylpretrichodermamid b nb biolog activ epidithiodiketopiperazin isol sever strain alga deriv fungus penicillium sp recent report first data activ human cancer cell line vitro investig activ select mecha...
D000970;D011471
T121;T191;T109
36,286,420
potenti epiderm growth factor like peptid sea cucumb stichopus horren increas growth human cell silico molecular dock approach sea cucumb promin tradit remedi among asian wound heal due high capac regener expuls intern organ short peptid consist amino acid transcriptom data stichopus horren sh egfl show convinc capabl ...
D047528;D012616
T204
36,286,419
cytotox potenti marin diatom thalassiosira rotula insight bioactiv methylen cholesterol marin microalga receiv great interest sustain sourc bioactiv metabolit health nutrit person care present studi bioassay guid screen allow identifi enrich fraction spe separ methanol extract marin diatom thalassiosira rotula chemic h...
D017377;D010840
T123;T121;T204;T109
36,286,418
ocean sunfish mola spp tetraodontiform molida repres risk tetrodotoxin poison portugues coast tetrodotoxin ttx potent neurotoxin natur occur terrestri marin organ pufferfish due risk ttx poison fish tetraodontida famili puffer relat speci must place eu market restrict appli fish famili molida even though data toxin occ...
D023721
T013
36,286,417
unusu tetrahydropyridoindol contain tetrapeptid human nicotin acetylcholin receptor target activ discov antarctica deriv psychrophil pseudogymnoascus sp hdn chemic investig psychrophil fungus pseudogymnoascus sp hdn deriv antarctica led discoveri six new tetrapeptid psegymamid f whose planar structur elucid extens nmr ...
D011978;D001203
T004;T116;T192
36,286,416
fucoxanthin product microalga differ cultur factor systemat review fucoxanthin one light harvest pigment brown microalga increas gain attent due numer health promot properti current product microalg fucoxanthin yet feasibl econom perspect howev cultiv microalga favour condit hold great potenti increas viabil fucoxanthi...
D058086
T204
36,286,415
phaeosphamid b cytotox cyclodecadepsipeptid mangrov deriv fungus phaeosphaeriopsi sp chemic examin ferment broth mangrov deriv fungus phaeosphaeriopsi sp result isol two new cyclodecadepsipeptid name phaeosphamid b well one known congen sch structur new metabolit includ absolut configur establish basi extens spectrosco...
D000970;D001203
T121;T004;T109
36,286,414
fucoidan incorpor composit scaffold stimul osteogen differenti mesenchym stem cell bone tissu engin global million bone graft procedur perform clinician annual treat rise preval bone defect studi design fucoidan sargassum ilicifolium incorpor osteo induct scaffold compris calcium crosslink sodium algin nano hydroxyapat...
D059630;D018786
T122;T025
36,286,413
ocellatuperoxid f uncommon anti tumor pyron peroxid photosynthet mollusk placobranchus ocellatus six new pair pyron polypropion enantiom unusu peroxyl bridg side chain name ocellatuperoxid f isol character south china sea photosynthet mollusk placobranchus ocellatus extens spectroscop analysi singl crystal x ray diffra...
D002289;D008175
T191
36,286,412
antimicrobi biosynthet potenti phylogenet analysi cultur bacteria associ spong ophlitaspongia sp yellow sea china spong deriv bacteria consid promis sourc novel drug owe abund secondari metabolit divers biolog activ studi explor antimicrobi biosynthet potenti phylogenet cultur bacteria associ spong ophlitaspongia sp ye...
D048630;D011161
T126;T116;T204
36,286,411
total synthes propos structur iriomoteolid b synthesi three deriv structur studi iriomoteolid iriomoteolid b potent cytotox agent isol marin dinoflagel carri enantioselect synthes propos structur natur product howev analysi nmr spectra synthet iriomoteolid natur product reveal structur iriomoteolid iriomoteolid b assig...
D018942;D001688
T121;T123;T109
36,286,410
enzym immobil metal organ framework effect buffer stabil support metal organ framework mof use encapsul array enzym rapid facil manner howev stabil mof support enzym examin detail studi examin stabil mof differ composit fe btc co tma ni tma cu tma zif zni buffer solut common use enzym immobil biocatalysi stabil assess ...
D000073396
T109
36,286,408
descend neuron popul dynam odor evok spontan limb depend behavior deciph brain regul motor circuit control complex behavior import long stand challeng neurosci fli drosophila melanogast coordin popul descend neuron dns activ dns known suffici drive complex behavior like walk groom howev addit role larger popul dns play...
D004331;D009812
T120;T070;T204
36,286,404
icodextrin use feasibl periton dialysi patient undergo f fdg petct scan f fdg petct scan use diagnost tool patient neoplasia inflammatori diseas evalu due interfer glucos cellular uptak f fdg tracer via glucos transport withhold glucos sourc sever hour imag mandatori also case periton dialysi patient glucos contain per...
D019788;D010530
T061;T130;T109
36,286,394
dri molten globul like intermedi protein fold function diseas perform protein depend correct fold final function nativ form henc understand process protein fold remain import field research scientif communiti past five decad two import intermedi state name wet molten globul wmg dri molten globul dmg emerg critic milest...
D017510;D058767
T044;T043
36,286,393
naphthalimid base fluoresc probe profil aldehyd oxid unsatur lipid lipophil naphthalimid hydrazin fluoresc probe success develop studi profil aldehyd oxid product dodecyl amin appli afford lipophil fluoresc probe lipid investig fluoresc properti probe condens product typic aldehyd includ mda hexan reveal signific enhan...
D005456;D053644
T130;T109
36,286,389
squar energi resolv mass spectrometri advanc quantit bile acid submetabolom character bile acid ba submetabolom partial reflect either physiolog patholog status vertebr structur divers howev extens hinder ba submetabolom clarif effort primarili devot enhanc structur annot confid bas particular conjug bas fortifi new te...
D001647;D053719
T063;T123;T109
36,286,261
use discret choic experi elicit prefer digit wearabl health technolog self manag chronic kidney diseas wearabl digit health technolog dhts potenti improv chronic kidney diseas ckd manag patient engag studi aim investig elicit prefer individu ckd toward wearabl dhts design support self manag condit
D000073278;D051436;D000076251
T058;T073;T047
36,286,260
protect omicron vaccin previous infect prison system inform regard protect confer vaccin previous infect infect b omicron variant sever acut respiratori syndrom coronavirus sar cov limit
D011330;D000086382
T047;T073;T067
36,286,256
earli activ mobil mechan ventil icu intens care unit icu acquir weak often develop patient undergo invas mechan ventil earli activ mobil may mitig icu acquir weak increas surviv reduc disabl
D012121;D004434
T061
36,286,250
methanol depend carbon fixat irrevers synthesi allulos xylos engin escherichia coli allulos rare hexos great applic potenti owe moder sweet low energi uniqu physiolog function current strategi allulos product whether industri develop util six carbon sugar glucos fructos substrat usual base principl revers izumor epimer...
D014994;D004926
T123;T007;T109
36,286,248
environment investig legionellosi outbreak montrgi quebec canada august legionellosi outbreak involv person occur within meter radius montrgi region qubec canada near real time model wind direct along epidemiolog environment investig identifi possibl sourc model wind direct could help identifi like legionella pneumophi...
D007876;D016952;D007877
T047;T007
36,286,246
serolog evid human exposur ehrlichiosi agent japan retrospect analys report febril patient japan seroconvers antibodi ehrlichia chaffeensi antigen detect use immunofluoresc western blot result provid evid autochthon human ehrlichiosi case indic ehrlichiosi consid potenti caus febril ill japan
D018469;D016873
T047;T007
36,286,232
presenc spirometra mansoni causat agent sparganosi south america report molecular identif adult spirometra mansoni tapeworm retriev crab eat fox cerdocyon thous colombia confirm presenc parasit south america tapeworm causat agent human sparganosi common report southeast asia repres second congener speci known zoonot po...
D013146;D013031;D002590
T047;T204
36,286,231
jamestown canyon virus collect mosquito main unit state jamestown canyon virus jcv mosquito born arbovirus circul north america detect jcv pool mosquito collect midcoast main usa phylogenet analysi jcv sequenc obtain aed cantat mosquito cluster within clade also circul connecticut usa
D002141;D009033;D001103;D000330
T005;T204
36,286,226
sequenc base identif metronidazol resist clostridioid difficil isol plasmid pcd metro confer metronidazol resist clostridioid difficil show high sequenc similar among pcd metro plasmid differ isol identifi pcd metro associ metronidazol resist isol clinic veterinari reservoir america recommend use pcr genom assay detect...
D016360;D003015
T047;T007;T037
36,286,225
silent transcript interv translat burst lead divers phenotyp switch gene express bimod potenti mechan generat phenotyp cell divers enhanc surviv cell fluctuat environ previous studi shown intrins extrins regul could induc bimod gene express unclear whether bimod occur without regul develop interpret tractabl model name...
D005786
T045
36,286,224
seroincid enter fever juba south sudan appli new serosurveil tool estim typhoid salmonella burden use sampl collect popul juba south sudan use dri blood spot test found enter fever seroincid rate person year cumul incid year period
D014435;D010284
T047
36,286,223
cluster norovirus genogroup ix outbreak long term care facil utah usa report cluster acut gastroenter outbreak long term care facil utah usa link healthcar employe work multipl facil four outbreak caus norovirus genotyp gix recommend continu norovirus surveil genotyp determin contribut genotyp norovirus outbreak
D029322;D017250
T005;T047
36,286,195
polyclon dissemin oxa carbapenemas produc klebsiella pneumonia franc increas preval oxacillinas produc enterobacteral observ franc most driven emerg klebsiella pneumonia whole genom sequenc identifi oxacillinas produc k pneumonia belong sequenc type sts among polyclon high risk clone st st overrepres
D007710;D000073182
T047;T007
36,286,192
effect lower vs higher oxygen satur target surviv hospit discharg among patient resuscit hospit cardiac arrest exact random clinic trial administr high fraction oxygen follow return spontan circul hospit cardiac arrest may increas reperfus brain injuri
D058687;D016887;D000086382
T061;T047;T046;T067
36,286,084
associ extracorpor membran oxygen new mental health diagnos adult survivor critic ill extracorpor membran oxygen ecmo use temporari cardiorespiratori support critic ill patient littl known regard long term psychiatr sequela among survivor ecmo
D015199;D019966
T061;T033;T048