PMID int64 35.7M 36.4M | Title/Abstract stringlengths 22 8.78k | MeshTerms stringlengths 7 101 | SemanticTypes stringlengths 4 64 |
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36,283,232 | migrat transform soil mercuri karst region southwest china implic groundwat contamin guizhou provinc locat heart karst zone southwest china one largest karst area world given fragil surfac ecosystem high develop underground karst structur migrat transform soil hg may impact groundwat qualiti karst environ high hg backg... | D008628;D060587 | T070;T082;T131;T196;T081 |
36,283,231 | effect dissolv organ matter bioavail toxic cadmium zebrafish larva determin base toxicokinet toxicodynam process presenc dissolv organ matter dom strong influenc bioavail metal aquat environ howev associ bind activ concentr dom composit well document lead uncertainti metal toxic assess creativ quantifi mitig acceler ef... | D002104;D014874 | T131;T196 |
36,283,230 | surfact sodium dodecyl sulfat enhanc degrad polystyren microplast energi save electrochem advanc oxid process eaop strategi microplast identifi kind emerg pollut potenti ecolog risk urgent endeavor find proper technolog remedi electrochem advanc oxid process eaop technolog exhibit robust perform remov various refractor... | D000080545;D014874 | T131;T122 |
36,283,177 | design synthesi vitro evalu novel antifung triazol contain substitut triazol methoxyl side chain order develop new triazol deriv optim lead compound structur modif obtain seri rr substitut h triazol yl methoxi difluorophenyl h triazol yl butan ol compound target compound exhibit excel vitro antifung activ candida albic... | D000935;D014230 | T121;T195;T109 |
36,283,176 | cc small molecular compound suppress multipl myeloma via upregul nur multipl myeloma mm hematolog malign plasma cell character product monoclon immunoglobulin protein despit signific advanc treatment mm remain incur disord owe resist chemotherapi refractori natur inhibitor histon deacetylas hdaci identifi promis therap... | D009101 | T191 |
36,283,145 | rocker profil design shoe improv pendular energi recoveri walk effect total mechan work rocker profil design shoe common use clinic set footwear reduc shoe pressur forefoot area gait depend rocker profil type ie toe heel negat doubl rocker affect lower limb kinemat kinet muscl electromyograph activ howev whether wear r... | D012775;D016138 | T169;T056;T073 |
36,283,138 | health facil risk factor multidrug resist gram negat bacteria critic ill patient covid relationship multidrug resist gram negat bacteria mdr gnb infect colon critic ill covid patient observ howev still poor understood studi evalu risk factor acquir mdr gnb patient sever covid intens care unit icu | D000086382;D003428;D016905 | T047;T067 |
36,283,127 | screen small molecul inhibitor rhoa protein alisma use onlin detect system target high throughput screen inhibitor natur product effect approach treatment cancer progress rhoa protein essenti mani signal pathway close relat occurr develop tumor far report screen small molecul inhibitor rhoa protein natur product studi ... | D034902;D001688 | T123;T121;T002 |
36,283,122 | fuse cycloheptatrien bodipi high perform near infrar probe imag tau tangl neurofibrillari tangl nfts compos abnorm hyperphosphoryl tau one main patholog hallmark alzheim diseas tauopathi fluoresc imag probe current use target nfts distinguish well amyloid plaqu thus limit util diagnos diseas develop fuse cycloheptatrie... | D024801;D000544 | T047;T048 |
36,283,107 | diverg pathway ammonia urea product excret life cycl sea lamprey littl known nitrogen wast n wast handl excret j n wast complex life cycl sea lamprey petromyzon marinus extant jawless fish undergo complet metamorphosi filter feed larva ammocoet parasit juvenil feed blood larger jaw fish investig ammonia urea handl prof... | D048428 | T013 |
36,283,082 | farewel great doctor extraordinari believ creator qualiti care dr hctor aguirr gas line farewel express dr hctor gerardo aguirr gas excel doctor great expon qualiti medic care patient safeti train servant medic servic instituto mexicano del seguro social imss nobl companion friend man univers ethic valu straight humbl ... | D011787;D012943 | T058;T064;T169 |
36,283,081 | clinic reason practic aspect allow facilit develop clinic reason compet doctor develop essenti medic practic clinic reason includ aspect relat observ critic think communic skill patient sinc integr previous knowledg doctor diseas medic problem obtain inform clinic aspect patient provid mental process process clinic inf... | D002983;D010820 | T097;T080 |
36,283,080 | bond natur fe co complex heme protein although carbon monoxid co known bind ferrous heme cytochrom p enzym ps sinc earliest day p research detail natur ferrous co bond remain elus studi employ dispers correct densiti function theori dft calcul dft base theoret analys investig complex co thiolat imidazol ligat heme cont... | D006420 | T123;T116 |
36,283,073 | syphilit chancr mouth unusu locat case report syphili infecti diseas caus spirochet treponema pallidum transmit main direct contact lesion primari syphili usual present chancr site infect high contagi resolv without treatment aim articl illustr unusu locat syphilit chancr order consid diagnosi within approach patient o... | D013587;D002601;D012871 | T184;T047 |
36,283,072 | salt induc dissolut protein aggreg protein aggreg mediat complex interplay noncoval interact associ broad rang aspect debilit human diseas food industri therapeut biotechnolog deciph intric role noncoval interact paramount import design effect inhibitori disaggreg strategi remain formid challeng use combin spectroscop ... | D066329;D011506 | T123;T116 |
36,283,071 | organocatalyt enantioselect nitrogen disubstitut aldehyd absenc solvent high effici enantioselect nitrogen method disubstitut aldehyd azodicarboxyl promot chiral carbam monoprotect cyclohexa diamin organocatalyst develop process carri without solvent correspond disubstitut nitrogen aldehyd obtain excel yield enantiosel... | D000447;D003959 | T109 |
36,283,069 | regio stereoselect norrish yang photocycl dialkyl diketon solut versus solid state photochemistri two polymorph shown x ray crystallographi crystal acetoxi seco dioxopregn ene nitril dimorph regioselect norrish yang type ii photocycl visibl light steroid diketon bear primari secondari tertiari nonequival abstract hydro... | D007659;D008027 | T070;T109 |
36,283,065 | cutan hyperpigment manifest acut chronic liver failur acquir cutan pigment repres littl recogn clinic manifest liver disord acut chronic occur exacerb process preexist hepatopathi context acut chronic liver failur sever hypothes increas pigment skin mucous membran develop tri explain defect degrad melanin secondari acc... | D065290;D017495 | T047;T046 |
36,283,060 | gastric pull caustic stenosi present complex clinic case chemic substanc import caus gastrointestin tract injuri usual affect two group patient children year age adult attempt suicid effect rang necrosi perfor digest tract affect mouth pharynx esophagus stomach main complic accident caustic ingest esophag strictur freq... | D002424;D002057;D004940 | T131;T197;T037;T047 |
36,283,057 | regul nitric oxid releas membran fluiditi ruthenium nitrosyl complex embed phospholipid vesicl incorpor water insolubl nitric oxid releas molecul biocompat vesicl may allow tunabl control releas specif target site vesicl membran fluiditi play import role influenc final therapeut effici drug load vesicl henc aim investi... | D012428 | T196 |
36,283,055 | medic econom certif cost budget health system health system necessari assess cost product servic magnitud budget oper formul histor public budget health complement zero base budget refer medic technic cost econom medic certif group relat diagnosi group relat outpati care imss prepar certif scenario treatment hospit out... | D000553;D017048 | T081;T058;T073;T093 |
36,283,054 | extens guidelin report type studi medicin use differ guid report type studi medic field wide dissemin decad howev adher use import part research still limit negat impact dissemin new find generat critic regard medic research design conduct report parallel extens guidelin littl known use personnel involv research work f... | D035843;D019317 | T062;T091 |
36,283,052 | unsupervis domain adapt extra featur target domain use optim transport domain adapt aim transfer knowledg label instanc obtain sourc domain target domain fill gap domain domain adapt method assum sourc target domain dimension method applic number featur differ domain rare studi especi label inform given test data obtai... | D000465;D007858 | T062;T170;T041;T061 |
36,283,051 | total synthes ineleganolid sinulochmodin c describ herein first total synthes furanocembranoid natur product ineleganolid sinulochmodin c synthet strategi predic transannular michael reaction provid natur product common macrocycl intermedi leverag diastereoselect radic cyclize furnish key bicycl lacton latter advanc ma... | D004224;D001688 | T123;T121;T109 |
36,283,044 | asymmetr complex pupil control model later imbalanc neural activ locus coeruleus potenti biomark attent deficithyperact disord locus coeruleus lc overact especi right hemispher recogn pathophysiolog attent deficithyperact disord adhd may relat inattent lc activ synchron kinet pupil diamet reflect neural activ relat cog... | D008125;D001289 | T023;T048 |
36,283,043 | memoryless optim neuron need adapt optim encod stimuli arbitrarili complex statist neuron seem capabl handl type data regardless scale statist properti letter suggest optim code may occur singl neuron level without requir memori adapt evolutionari driven fit stimuli refer neural circuit optim maxim mutual inform input ... | D008959;D009474 | T170;T025 |
36,283,042 | larg scale algorithm search identifi stiff sloppi dimens synapt architectur consist murin neocort wire complex system defin sloppi dimens mean behavior unmodifi larg chang specif paramet combin stiff dimens whose chang result consider behavior modif neocortex sloppi synapt architectur would crucial allow mainten asynch... | D019579;D014793 | T023;T029;T024 |
36,283,040 | polici strategi combat obes latin america latin america region highest preval overweight obes therefor strategi polici implement countri reduc health problem among fiscal polici tax sugari drink high calori product regul advertis food label | D050177;D013660 | T033;T081;T064 |
36,283,034 | epidemiolog clinic characterist covid epidem mexico quintana roo case identifi risk factor sever outcom mexican patient covid popul quintana roo | D000086382;D003920;D006973 | T047;T067 |
36,283,033 | impact germin brown rice brown rice metabol inflamm gut microbiom high fat diet induc insulin resist mice constitu germin brown rice gbr brown rice brr white rice whr impact metabol inflamm gut microbiota high fat hf diet fed mice examin content total fiber aminobutyr acid brr gbr higher whr p male c blj mice receiv hf... | D000069196;D012275;D007333 | T007;T001;T168;T046;T002 |
36,283,027 | physic inact young peopl home confin due covid physic inact high preval condit world associ increas suscept develop comorbid present sever respiratori distress syndrom due covid | D057185;D000086382 | T033;T047;T079;T067 |
36,283,026 | epidemiolog clinic characterist survivor sar cov infect descript studi march world health organ declar pandem coronavirus typic symptom fever cough asthenia dyspnea muscl pain pulmonari central nervous system compromis present challeng characterist healthcar physician object studi identifi epidemiolog clinic characteri... | D000086382;D000370 | T184;T067;T033;T047;T048 |
36,283,025 | synthesi evalu prodrug carboxi nucleosid phosphon rang lipophil prodrug carboxi nucleosid phosphon potent inhibitor hiv revers transcriptas without requir prior phosphoryl synthes evalu vivo potenc hiv cell cultur seri prodrug deriv bear free carboxyl acid phosphon mask bispivaloyloxymethyl diisopropyloxycarbonyloxymet... | D063065;D011355;D019380 | T120;T131;T121;T109 |
36,283,017 | asept loosen joint prosthes asept observ chang periarticular space may caus mechan action biolog reaction periprosthet infect common caus loosen destruct chang joint howev diagnosi asept reaction alway fulli obvious micromov implant surround bone caus remodel bone trabecula migrat fibroblast void implant surfac bone ad... | D007595;D010014 | T074;T046 |
36,283,016 | nativ heart valv thrombosi associ covid report case nativ heart valv thrombosi nhvt rare valvular patholog usual associ prothrombot state disturb intracardiac blood flow relat structur valv abnorm differ venous arteri thromboembol complic covid wide describ far nhvt report context diseas author describ case nhvt associ... | D000086382;D006331;D003328 | T047;T067 |
36,283,015 | diagnost difficulti igg relat diseas case report igg relat diseas belong group immun mediat diseas relat new condit classifi character involv multipl organ time caus organ failur observ radiolog chang slow grow rule cours diseas subclin mean diagnosi often made incident retrospect mani year onset symptom initi stage di... | D000077733;D056647 | T033;T047 |
36,283,014 | efficaci rituximab minim chang diseas atyp renal manifest antiphospholipid syndrom antiphospholipid syndrom ap defin presenc antiphospholipid antibodi along hypercoagul event renal involv ap usual manifest thromboembol complic observ larg blood vessel small intraren vessel ap nephropathi report rare case glomerul assoc... | D016736;D009402;D009404;D007674 | T047 |
36,283,013 | nephrolog urolog symptom patient robinow syndrom report two case robinow syndrom rare congenit syndrom describ meinhard robinow genet background heterogen mutat dvli dvli wnta gene mild autosom domin inherit ror gene sever autosom recess inherit respons syndrom syndrom character facial dysmorph skelet defect short stat... | D014718;D009398;D017880;D004392 | T019;T047;T091 |
36,283,012 | implant av leadless pacemak case report earli food drug administr fda approv micra av new type leadless pacemak atrioventricular synchroni treat patient atrio ventricular av block describ one first poland case patient implant micra av pacemak | D054537;D010138;D004696 | T047;T074 |
36,283,011 | current therapeut option treatment secondari hyperparathyroid end stage renal diseas patient treat hemodialysi month compar studi aim studi investig effect new calcimimet etelcalcetid secondari hyperparathyroid effect end stage renal diseas esrd patient treat hemodialysi hd compar hemodialysi hd patient treat calcimime... | D006962;D007676 | T047 |
36,283,010 | respiratori microbiota good predictor outcom humor immunodefici methodolog conceptu difficulti comprehens microbiom analysi microbiom broad term defin dynam ecolog system apart biocenosi uniqu nich develop equal dynam host deriv contrari physic environ ecolog although year antibodi recogn key element mucos barrier stil... | D064307;D000069196 | T001;T032;T028;T007 |
36,283,009 | warto prognostyczna wskanikw elektrokardiograficznych zawau prawej komori w oceni wewntrzszpitalnego przebiegu klinicznego u chorych z rozpoznanym zawaem ciani dolnej leczonych interwencyjni myocardi infarct mi right ventricl rv coexist patient inferior mi electrocardiograph indic connect rv mi may also predict unfavor... | D054537;D000072657;D009203 | T047 |
36,283,008 | role serotonin pathogenesi unclassifi irrit bowel syndrom pathogenesi irrit bowel syndrom ib clear understood numer factor includ neurotransmitt interfer function digest tract | D043183;D008550 | T125;T121;T047;T109 |
36,283,007 | cytolog transform cervix immunodefici aggrav alcohol comorbid patholog high mortal disabl remain urgent problem peopl develop immunodefici state includ women reproduct age prognost trigger could help improv manag preneoplast injuri cervic epithelium | D015658;D000437;D002583 | T047;T191;T048 |
36,282,995 | delta neutrophil lymphocyt index mortal covid diseas acut respiratori distress syndrom due sar cov worldwid health problem neutrophil lymphocyt index allow risk stratif patient sever poor prognost data sinc reflect inflammatori state | D000086382;D012128 | T047;T067 |
36,282,994 | activ two photon near infrar ratiometr fluoresc nanoprob onoo detect earli diagnosi assess liver injuri liver injuri pose serious threat human health grow evid suggest close associ biomark peroxynitrit onoo therefor consid relationship onoo level occurr develop liver injuri diseas remain challeng urgent need exist deve... | D030421;D005456 | T123;T197;T130 |
36,282,989 | base trisubstitut alken environment sensit fluoresc probe detect lewi patholog lewi patholog main consist insolubl synuclein syn aggreg hallmark parkinson diseas mani neurodegen diseas term synucleinopathi detect lewi patholog optic method interest preclin studi syn fluoresc probe still great demand ration design obtai... | D005456;D010300 | T047;T130 |
36,282,987 | etiolog bacteri pneumonia patient covid aggreg bacteri pneumonia play fundament role mortal patient hospit covid | D000086382;D018410 | T047;T067 |
36,282,974 | socio labor condit psycholog burnout worker pandem compar studi pandem deriv covid caus great impact context wich human oper includ labor context multipl studi shown influenc covid pandem public privat organ deriv import assess real work context mexican popul time pandem factor relat appear psycholog exhaust | D000086382;D002055 | T047;T067;T048 |
36,282,961 | molecular inform theori meet protein fold propos applic molecular inform theori analyz fold singl domain protein analyz result various area protein scienc sequenc base potenti reduc amino acid alphabet backbon configur entropi secondari structur content residu burial layer mutat studi protein stabil chang found averag ... | D007257;D017510 | T090;T044 |
36,282,958 | valor wast tungsten filament mpg c n wo photocatalyst sustain e wast manag wastewat treatment wast tungsten filament materi environ one reason environment pollut danger anim plant date much attent given util recycl herein present work report synthesi tungsten trioxid nanoparticl wo nps util cost free wast tungsten fila... | D059029;D018508 | T068;T052;T057 |
36,282,957 | simpl blood vessel imag protocol live zebrafish larva zebrafish larva simpl model system studi blood vessel develop excel optic properti current method studi blood vessel zebrafish involv util either blood vessel specif transgen line special techniqu microangiographi video capillaroscopi studi develop simpl protocol us... | D015027;D011794 | T121;T109;T127;T013 |
36,282,955 | acetonitril ligand photosubstitut ru ii complex direct mlct state excit state seri ru tpi l ch cn n n contain bident ligand l vari electron donat abil character arrhenius analysi temperatur depend excit state lifetim complex undergo photoinduc ch cn dissoci upon nm irradi ligand exchang quantum yield increas energi bar... | D012428 | T196 |
36,282,953 | sodium isopropyl trimethylsilyl amid stabl high solubl lithium diisopropylamid mimic prepar structur physic properti reactiv sodium isopropyl trimethylsilyl amid napta describ solubl room temperatur rang n heptan n hexan toluen mtbe et n thf half life destruct neat thf year c day c compar favor month day respect lda ne... | D012964;D000577 | T123;T196;T034;T109 |
36,282,945 | reduct rare earth metal complex induc irradi util irradi generat unstabl low oxid state molecular speci contain rare earth metal ion frozen solut examin method evalu irradi ln iii precursor ln sc la solid matrix methyltetrahydrofuran k kev cs sourc generat free electron capabl reduc ln iii speci experi yield epr uv vis... | D056831;D008674 | T104;T196 |
36,282,937 | health care resourc util cost among individu vs without huntington diseas us popul background quantifi extent health care resourc util hcru cost associ huntington diseas hd vital provid decisionmak payer understand unmet treatment need ensur limit resourc use benefit maximum number peopl hd object quantifi hcru cost pe... | D017048;D006816 | T081;T047 |
36,282,935 | comparison real world clinic econom outcom patient receiv oral anticoagul retrospect claim analysi background direct oral anticoagul doac becom wide use prevent stroke nonvalvular atrial fibril af treatment venous thromboembol vte warfarin standard care prior doac requir monitor dose adjust ensur patient remain appropr... | D054556;D001281;D020521;D011655 | T047;T046 |
36,282,934 | trend endpoint use pivot trial efficaci us food drug administr approv solid tumor therapi background mani cancer therapi approv base surrog endpoint progress free surviv pfs ensur patient speedi access life save cancer medicin howev link surrog endpoint overal surviv os well establish mani cancer object character trend... | D008175;D001943 | T191 |
36,282,933 | ad ribociclib fulvestr cost effect treat postmenopaus women hrher advanc metastat breast cancer us payer perspect cost util analysi background breast cancer preval type cancer women unit state ribociclib plus fulvestr combin therapi gain us food drug administr approv treat postmenopaus women hormon receptor positivehum... | D001943 | T191 |
36,282,932 | health care cost util prior diagnosi antineutrophil cytoplasm antibodi vascul medicar beneficiari background antineutrophil cytoplasm antibodi anca vascul av complex group autoimmun disord affect blood vessel multipl organ system delay diagnosi common av symptom nonspecif present heterogen may result increas health car... | D055553;D014657 | T121;T047 |
36,282,931 | within trial econom analysi resourc use comet ice phase clinic trial evalu sotrovimab treatment patient covid high risk progress background final result primari endpoint covid monoclon antibodi efficaci trial intent care earli comet ice random control trial nct show p adjust relat risk reduct longer hour hospit death d... | D000086382 | T047;T067 |
36,282,930 | real world opioid use among patient migrain enrol us commerci insur risk factor associ migrain progress background migraineur may categor episod migrain em mmeday month follow period higher opioid dosag found patient cm comorbid interest compar patient em patient cm twice like receiv least mmeday cm vs em higher median... | D009293;D008881;D007341 | T078;T047;T081;T048 |
36,282,929 | trend add medic follow metformin monotherapi type diabet background although metformin general univers recommend first line pharmacolog therapi peopl live type diabet second line third line choic requir tailor approach achiev optim blood glucos glycat hemoglobin level object examin nation trend second third line antihy... | D008687;D003924;D054873 | T121;T047;T109 |
36,282,928 | specialti pharmaci turnaround time impedi facilit good practic background patient receiv specialti medic condit often complex high cost high need prompt treatment initi essenti appropri manag mani condit treat specialti product improv turnaround time tat specialti pharmaci prescript help ensur patient receiv medic need... | D010594;D010593;D010604;D008511 | T091;T073;T093;T170;T058;T057 |
36,282,927 | drug super spender tsunami integr medic pharmaci benefit assess background new rare diseas drug therapi gene therapi high price cancer drug receiv us food drug administr approv increas potenti drug super spender individu annual drug cost object categor member larg commerci insur popul total annual combin drug cost medi... | D000970;D010604 | T121;T091;T057;T109 |
36,282,926 | health care resourc util cost associ atrial fibril rural urban dispar background atrial fibril af impos substanti health care econom burden health care system patient previous studi fail examin health care resourc util hcru cost among patient incid af potenti dispar regard geograph locat object examin hcru cost among p... | D001281 | T047;T046 |
36,282,925 | covid adher biolog therapi psoriasi analysi nationwid pharmaci claim data background earli onset covid pandem concern rais use psoriasi treatment particular biolog therapi immunosuppress effect could associ poor prognosi case covid infect object examin chang adher systemat biolog therapi psoriasi onset covid pandem met... | D000086382;D011565;D010604 | T047;T091;T067;T057 |
36,282,923 | solid phase base synthesi lactazol like thiopeptid strategi synthesi de novo discov lactazol like thiopeptid report approach revolv around converg scalabl prepar central triheterocycl amino acid util fmoc solid phase peptid synthesi modular peptid chain assembl techniqu prepar c termin function thiopeptid biolog studi ... | D060327;D010455 | T121;T116;T052;T059 |
36,282,922 | de novo discoveri thiopeptid pseudo natur product act potent select tnik kinas inhibitor bioengin ribosom synthes post translate modifi peptid ripp emerg approach explor divers pseudo natur product structur drug discoveri purpos howev despit initi advanc area bioactiv reprogram multienzym ripp biosynthet pathway remain... | D001688 | T123;T121 |
36,282,921 | phosphoryl rxr mediat effect jnk suppress hepat fgf express promot metabol syndrom cjun nh termin kinas jnk signal pathway liver promot system chang metabol regul peroxisom prolifer activ receptor ppar depend express hepatokin fibroblast growth factor fgf hepatocyt specif gene ablat studi demonstr mapk gene encod jnk p... | D024821;D047493 | T047;T116;T192 |
36,282,920 | coordin expertis foster legal textual cross cultur survey experi reveal domin tendenc reli rule letter spirit decid behavior violat rule tendenc vari mark across k countri owe variat impact moral apprais judgment rule violat compar laypeopl legal expert inclin disregard moral evalu act altogeth consequ exhibit stronger... | D009014;D007600 | T078;T041 |
36,282,919 | morpholog growth dynam mechan stabil activ microtubul mechan under spindl self organ spindl dynam intracellular structur self organ microtubul microtubul associ protein spindl bipolar morpholog essenti faith segreg chromosom cell divis robust maintain multifacet mechan howev abnorm shape spindl multipolar spindl stocha... | D016547;D008941 | T026;T123;T126;T116 |
36,282,918 | childhood hemispherectomi one hemispher support suboptim word face recognit right left cerebr hemispher import face word recognit respect special emerg human develop question whether bilater distribut necessari whether singl hemispher left right support face word recognit face word recognit accuraci patient median age ... | D038421;D000066499 | T061;T041 |
36,282,917 | swap sfps rrc splice factor complex modul pre mrna splice promot photomorphogenesi arabidopsi light signal perceiv group photoreceptor profound effect physiolog growth develop plant redfar red light absorb phytochrom phys modul aspect intric regul gene express multipl level report identif function character rna bind sp... | D017360;D029681;D010834 | T123;T116;T002 |
36,282,916 | adar regul apol via rna edit inhibit mda activ paradox biolog circuit apol risk variant associ increas risk kidney diseas patient african ancestri individu apol high risk genotyp develop kidney diseas apol gene express correl close degre kidney cell injuri cell anim model mechan regul apol express may critic determin r... | D000243;D007370 | T129;T121;T126;T116 |
36,282,915 | loss repressor rest affect progesteron receptor function promot uterin leiomyoma pathogenesi uterin leiomyoma ul benign tumor aris myometri layer uterus standard treatment option ul hysterectomi although hormon therapi select progesteron receptor modul often use temporari treatment option reduc symptom slow growth tumo... | D007889;D014594 | T191 |
36,282,914 | role gtp hydrolysi ef g ribosom transloc transloc transfer rna trna messeng rna mrna ribosom catalyz gtpase elong factor g ef g bacteria although guanosin triphosph gtp hydrolysi acceler transloc requir dissoci ef g fundament role remain unclear use ensembl frster reson energi transfer fret monitor inhibit gtp hydrolys... | D020653;D012270 | T026;T126;T116 |
36,282,913 | theta pattern stimul induc synapt intrins potenti lm interneuron brain oscil long last effect synapt cellular properti instanc synapt stimul theta frequenc induc persist depress excitatori synapt transmiss intrins excit ca princip neuron howev incid activ synapt transmiss intrins excit hippocamp gabaerg interneuron unc... | D018091;D002118 | T123;T121;T116;T192;T196 |
36,282,912 | robust core architectur function brain network support topolog resili cognit perform middl old age adult age associ gradual chang cognit yet individu exhibit protect age relat cognit declin topolog characterist brain network promot protect cognit declin age unknown investig whether robust resili brain network queri via... | D008279;D001921 | T060;T023;T170;T059 |
36,282,911 | host protein kinas requir sar cov nucleocapsid phosphoryl viral replic multipl coronavirus emerg independ past year caus lethal human diseas although vaccin develop target virus acceler substanti remain patient requir treatment vaccin experi breakthrough infect understand common host factor necessari life cycl coronavi... | D000086402;D000086382 | T005;T067;T047 |
36,282,910 | yap taz promot osteogenesi prevent chondrogenesi neural crest cell vitro vivo neural crest cell nccs multipot stem cell differenti multipl cell type includ osteoblast chondrocyt constitut craniofaci skeleton show vitro vivo studi transcript regul yap taz redund function key determin specif differenti nccs osteoblast ch... | D020219;D010012 | T042 |
36,282,909 | modul macrocycl peptid cell permeabl macrocycl peptid antagon either activ inact state g fine tune signal | D010455;D015398 | T121;T116;T044;T043 |
36,282,905 | immun mediat inflammatori diseas anti sar cov vaccin new diagnos diseas flare new onset immun mediat inflammatori diseas imid flare pre exist imid report follow anti sar cov vaccin studi aim describ retrospect cohort patient develop new onset imid flare known imid within day anti sar cov vaccin dose | D001327;D000086382;D014612 | T129;T121;T116;T067;T047 |
36,282,904 | ion dipol correct drism solvat model accur comput water distribut around negat charg biomolecul refer interact site model drism provid effici grid base solvat model comput structur thermodynam properti biomolecul aqueous solut howev remain challeng exist drism method correct predict water distribut around negat charg s... | D014867;D009711 | T121;T197;T114 |
36,282,903 | treatment lisfranc injuri year old boy case report surgic techniqu case year old boy lisfranc injuri identifi weight bear film treat success close reduct clamp smooth pin fixat patient return sport without pain radiograph sign arthriti year | D050723;D004204 | T037 |
36,282,902 | popul dynam baltic herring sinc vike age reveal ancient dna genom world ocean current face major stressor form overexploit anthropogen climat chang baltic sea home first industri fisheri ago target baltic herring speci still econom cultur import today yet earli origin marin industri long term ecolog consequ histor cont... | D005398;D000072441 | T092;T123;T114 |
36,282,893 | slow progress toward pneumonia control children low middl incom countri measur pneumonia indic systemat review literatur integr global action plan prevent control pneumonia diarrhoea gappd goal end prevent childhood death pneumonia diarrhoea target indic monitor progress aim systemat review summaris low middl incom cou... | D003906;D011014 | T047;T050;T080 |
36,282,892 | singl nanoparticl count base liquid biopsi cancer diagnosi liquid biopsi becom sought techniqu diseas diagnosi provid real time dynam comprehens inform allevi dilemma face tissu biopsi multiplex microrna mirna demonstr promis biomark liquid biopsi fall short provid simpl sensit analyt method work establish novel nanopa... | D035683;D001943;D053758 | T123;T191;T073;T114 |
36,282,886 | fulli autom crispr lamp platform sar cov delta omicron variant integr cluster regular interspac short palindrom repeat crispr loop mediat amplif lamp technolog great import crispr base diagnost system urgent need develop improv diagnost accuraci labor free contamin free fulli autom droplet manipul platform crispr lamp ... | D000086402;D000086382 | T005;T067;T047 |
36,282,885 | heart rate variabl risk heart failur subtyp post menopaus women women health initi studi low heart rate variabl hrv measur autonom imbal associ increas risk coronari heart diseas chd heart failur hf howev relationship hf subtyp heart failur preserv eject fraction hfpef heart failur reduc eject fraction hfref studi prio... | D006333;D003327 | T047;T046 |
36,282,884 | adher low risk diseas public health measur covid pandem qualit studi public health measur phms proactiv reactiv reduc spread diseas measur target individu behaviour requir broad adher effect consequ world health organ issu special appeal young adult known non adher popul increas adher covid guidelin howev littl known l... | D000086382 | T047;T067 |
36,282,879 | risk cardiovascular diseas patient alcohol use disord popul base retrospect cohort studi complex effect alcohol consumpt cardiovascular system vari mean daili consumpt durat intak popul base retrospect cohort studi aim explor risk cardiovascular diseas cvd patient alcohol use disord aud data collect taiwan nation healt... | D000437;D002318;D020521 | T047;T048 |
36,282,878 | molecular epidemiolog kaposi sarcoma virus spain sinc human herpesvirus hhv infect may underestim hhv subtyp circul spain remain unknown molecular epidemiolog studi high desir | D012514;D019288;D000163;D006566 | T005;T191;T047 |
36,282,872 | contact len safeti correct refract error healthi eye contact lens safe effect method correct refract error worn estim million american widespread avail commerci popular contact lens well appreci public contact lens us food drug administr fda regul medic devic contact lens market numer hard soft materi improv decad worn... | D003261;D012030;D007634;D003262;D003263 | T047;T074 |
36,282,866 | funhop analysi reveal upregul mitochondri gene prostat cancer mitochondri activ cancer cell central cancer research sinc otto warburg first publish thesi topic although warburg propos oxid phosphoryl tricarboxyl acid tca cycl perturb cancer later research shown oxid phosphoryl activ cancer includ prostat cancer pca how... | D050259;D011471 | T045;T191;T028 |
36,282,865 | signal valu drive engag multi round inform intervent inform intervent effect recipi must first engag show engag repeat digit inform intervent shape subtl strateg control signal inform valu particular recipi expect shape signal envelop surround messag inform intervent envelop convey clue messag reveal messag peopl expec... | D011795 | T098;T062;T170;T081;T057 |
36,282,864 | interest without uptak mix method analysi methadon util kyrgyz prison hiv incid continu increas eastern europ central asia eeca larg part due non steril inject drug use especi within prison therefor medic assist therapi opioid agonist evid base hiv prevent strategi kyrgyz republ offer methadon within prison system upta... | D011329;D009293;D000163 | T047;T098;T048 |
36,282,862 | next generat kras target reason excit concern develop select krasgc inhibitor direct inhibit kras oncogen histor thought undrugg repres watersh moment oncolog development therapeut kras target therapi move second phase signific excit anticip durabl diseas control tumor type option remain limit clinic trial test combin ... | D016283;D000970 | T121;T126;T116;T109 |
36,282,861 | role npm altern splice patient chronic lymphocyt leukemia chronic lymphocyt leukemia cll lymphoprolif diseas heterogen clinic cours recent studi reveal link notch mutat overexpress myc myc relat gene involv ribosom biogenesi protein biosynthesi nucleophosmin npm cll cell present studi aim evalu impact notch mutat myc m... | D015451 | T191 |
36,282,860 | perceiv listen abil hear loss systemat review qualit meta synthesi hear loss hl affect communic complex way understand adult hl reflect conceptualis way listen metacognit requir intervent outcom measur use evalu address barrier function communic aris hl | D034381;D003638 | T033;T184;T047 |
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