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cli::cli_h2("┗ [Vasc-AoP] Setting project's plots & tables' themes") #---------------# ####🔺Colors #### #---------------# bg_color_light <- "white" primary_color_light <- "black" secondary_color_light <- "#0d6efd" bg_color_dark <- "#222" primary_color_dark <- "white" secondary_color_dark <- "#20c997" strip_color <...
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library(Seurat) library(tidyverse) library(cluster) #library(factoextra) library(dendextend) library(weights) library(ggpubr) library(matrixStats) library(readxl) base_dir <- "/n/scratch/users/s/sad167/EPN/scRNAseq" resources_dir <- file.path(base_dir, 'scripts/resources') source(file.path(resources_dir, 'single_cell...
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library(ggplot2) library(dplyr) library(cowplot) library(here) library(tidyr) ## Environment -- here::i_am("Rscripts/Figure_S1_Spontaneous_Aggregated.R") ## Functions -- generate_boxplots <- function(input_data, X, Y, min,max){ data<-as.data.frame(input_data) #Ensure correct ordering of levels #data$Genotype <...
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library(tidyverse) library(synExtra) library(synapser) library(powerjoin) # Select ROSMAP samples that use rRNA depletion instead of poly-A enrichment # in library prep. Can't quantify repeat transcripts in samples prepared # using poly-A enrichment synLogin() syn <- synDownloader("~/data", .cache = TRUE) rosmap_cl...
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#!/usr/bin/env Rscript library(broom.mixed) library(dplyr) library(lme4) library(lmerTest) library(optparse) library(tidyverse) library(vroom) has_random_effect <- function(formula) { length(lme4::findbars(formula)) > 0 } fit_model <- function(formula, data, ...) { if (has_random_effect(formula)) { model <- ...
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### Indexing functions from: # https://stackoverflow.com/questions/39005958/r-how-to-get-row-column-subscripts-of-matched-elements-from-a-distance-matri ## 2D index to 1D index # IMPORTANT: Modified for transposition of rows/columns. # If j > i, swap i and j to return the appropriate distance (using the fact that # t...
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library(here) library(ggplot2) library(dplyr) library(nlme) library(cowplot) library(tidyr) library(emmeans) ## Environment -- here::i_am("src/Figure_3_TH_staining.R") generate_violinplots <- function(input_data, X, Y, min,max){ data<-as.data.frame(input_data) ggplot(data=data,aes(x={{X}},y={{Y}}, fill={{X}})) ...
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--- title: "VWFA_methods_LMEs" author: "Jamie Mitchell" date: "2025-07-22" output: html_document --- Set Up ```{r setup-pt1} library("lme4") # for linear mixed effects models library("tidyverse") # for wrangling library("glue") # for setting paths library("lmerTest") # for linear mixed effects m...
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## This R code facilitates the creation of a boxplot with overlaid scatter points for grip strength data, categorized by the variable 'Virus' and colored according to 'Light'. Modifications to the R code will be required for other behavioral datasets.# Sample data:grip strength data, grouped by Virus and colored by Lig...
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setwd("~/Documents/yu_lab/kernels_in_GP/Kick_data/") library(tidyverse) library(multcomp) source("src/scales.R") ref_pcs <- read_csv("processed/reference_sorted.csv", show_col_types = FALSE) y <- scale(ref_pcs$GrainYield[ref_pcs$Set == "Train"]) yc <- attr(y, "scaled:center") ys <- attr(y, "scaled:scale") ref_pcs <...
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# Function to preprocess the xenium sequencing output (creates seurat object, find markers for # different resolutions and score the signatures) # spatially_subset_coords is a vector storing 4 numerics (xmin, xmax, ymin, ymax) indicating how to spatially subset the sample # This function both saves the processed file ...
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prepare_test_datasets = function(subset_n_rows = NA) { ### example dataset and application of MS-EmpiRe following the documentation at: https://github.com/zimmerlab/MS-EmpiRe/blob/master/example.R f <- system.file("extdata", "c1_c3.data", package = "msEmpiRe") p <- system.file("extdata", "c1_c3.pdata", package =...
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#'@title Pairwise multilevel comparison using adonis #' #'@description This is a wrapper function for multilevel pairwise comparison #' using adonis() from package 'vegan'. The function returns adjusted p-values using p.adjust(). #' #'@param x Data frame (the community table), or "dist" object (user-supplied distance m...
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library(dplyr) df <- read.csv("Analysis_Files/ASO/ASO Wire Hang - Wire_Hang.csv",header=TRUE) df$SLC_Genotype <- factor(df$SLC_Genotype, levels= c("WT","HET", "MUT")) ### Data Wrangling --- df <- df %>% group_by(MouseID) %>% mutate(Exclusion = ifelse(all(Sincerity_Score_Relaxed == "Insincere"), "Yes", "No")) v1 ...
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setwd("~/Documents/yu_lab/kernels_in_GP/Kick_data/") library(tidyverse) library(keras3) library(kerastuneR) HyperModel <- PyClass( "HyperModel", inherit = HyperModel_class(), list( build = function(self, hp) { clear_session(free_memory = TRUE) model <- keras_model_sequential(input_shape = c(28...
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## These are utility functions not meant to be exposed to the user #' @importFrom methods slot #' @importFrom Matrix rowSums .check_empty <- function(x, attribute){ # check if a Milo object slot is empty or not x.slot <- slot(x, attribute) if(is.list(x.slot) & names(slot(x, "graph")) == "graph"){ ...
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setwd("~/Documents/yu_lab/kernels_in_GP/Kick_data/") library(tidyverse) library(tensorflow) tf$config$list_logical_devices() library(keras3) library(kerastuneR) HyperModel <- PyClass( "HyperModel", inherit = HyperModel_class(), list( build = function(self, hp) { clear_session(free_memory = TRUE) ...
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setwd("~/Documents/yu_lab/kernels_in_GP/Kick_data/") library(tidyverse) library(tensorflow) tf$config$list_logical_devices() library(keras3) library(kerastuneR) HyperModel <- PyClass( "HyperModel", inherit = HyperModel_class(), list( build = function(self, hp) { clear_session(free_memory = TRUE) ...
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#!/usr/bin/Rscript pkg.list <- installed.packages()[,"Package"] if (!("argparse") %in% pkg.list) { install.packages("argparse") } if (!("zeallot") %in% pkg.list) { install.packages("zeallot") } # taken from: # https://stackoverflow.com/questions/47044068/get-the-path-of-current-scriptk getCurrentFileLocatio...
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#'@title Pairwise multilevel comparison using adonis accepting strata #' #'@description This is a wrapper function for multilevel pairwise comparison #' using adonis() from package 'vegan'. The function accepts interaction between factors and strata. #' #'@param x Model formula. The LHS is either community matrix or di...
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setwd("~/Documents/yu_lab/kernels_in_GP/Kick_data/") library(tidyverse) source("src/kernel_functions.R") ### Load the hybrid marker matrix --------------------------------------------- # From Lopez-Cruz et al. (2023) pcs <- read_rds("09.pc_comparison/hybrid_pc_scores.rds") ### Load the reference pedigree list ----...
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library(here) library(ggplot2) library(rlang) library(rstatix) library(nlme) library(cowplot) library(ggbeeswarm) library(ggpubr) library(ggsignif) library(knitr) library(here) here::i_am("Rscripts/MPTP/MPTP_Rotarod.R") data <- readr::read_csv(here("Analysis_Files", "MPTP","MPTP_Rotarod.csv")) data$SLC_Genotype <- f...
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R
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# CPM -------------------------------------------------------------------- .calculateCPM <- function(countData) { CPM <- apply(countData,2, function(x) { (x/sum(x))*1000000 }) return(CPM) } # TPM --------------------------------------------------------------------- # accounting for gene lengths .calculateTPM <...
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setwd("~/Documents/yu_lab/kernels_in_GP/Kick_data/") library(tidyverse) library(tensorflow) tf$config$list_logical_devices() library(keras3) library(kerastuneR) library(abind) HyperModel <- PyClass( "HyperModel", inherit = HyperModel_class(), list( build = function(self, hp) { clear_session(free_me...
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setwd("~/Documents/yu_lab/kernels_in_GP/Kick_data/") library(tidyverse) library(tensorflow) tf$config$list_logical_devices() library(keras3) library(kerastuneR) library(abind) HyperModel <- PyClass( "HyperModel", inherit = HyperModel_class(), list( build = function(self, hp) { clear_session(free_me...
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#' placeholder title #' @param tib_input todo #' #' @importFrom ggpubr ggarrange theme_classic2 plot_dia_cscore_histograms = function(tib_input) { if(length(tib_input) < 2 || !is_tibble(tib_input)) { return(list()) } if(!all(c("cscore", "isdecoy") %in% colnames(tib_input)) || !any(tib_input$isdecoy)) { a...
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library(ggplot2) library(vegan) library(dplyr) library(rlang) library(cowplot) library(viridis) setwd("/Users/rochellelai/Documents/JacobsGit/slcproject/PFF_Microbiome/beta_diversity/") # here::i_am("PFF_Microbiome_RProj/_Beta_Diversity.R") ### Read data data_meta <- "/Users/rochellelai/Documents/JacobsGit/slcproject...
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setwd("~/Documents/yu_lab/kernels_in_GP/Kick_data/") library(tidyverse) library(tensorflow) tf$config$list_logical_devices() library(keras3) library(kerastuneR) library(abind) HyperModel <- PyClass( "HyperModel", inherit = HyperModel_class(), list( build = function(self, hp) { clear_session(free_m...
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setwd("~/Documents/yu_lab/kernels_in_GP/Kick_data/") library(tidyverse) library(tensorflow) tf$config$list_logical_devices() library(keras3) library(kerastuneR) library(abind) HyperModel <- PyClass( "HyperModel", inherit = HyperModel_class(), list( build = function(self, hp) { clear_session(free_m...
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setwd("~/Documents/yu_lab/kernels_in_GP/Kick_data/") library(tidyverse) library(multcomp) source("src/scales.R") ref_pcs <- read_csv("processed/reference_sorted.csv", show_col_types = FALSE) y <- scale(ref_pcs$GrainYield[ref_pcs$Set == "Train"]) yc <- attr(y, "scaled:center") ys <- attr(y, "scaled:scale") ref_pcs <...
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base_dir <- "/Users/sdaniell/Dropbox (Partners HealthCare)/Project_HOPE/SARA" # Read metadata file with patient information ----------------------------------- oncoprint_input_tumors <- read_excel(file.path(base_dir, 'metadata/metadata_10X_smartseq.xlsx')) # remove samples with no goodQC cells left postQC badqc <- c...
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#' Plot method for Epoch objects #' #' @param x An Epoch object #' @param y Not used (for S4 method compatibility) #' @param gap Numeric value specifying the gap between electrode traces (default: 2) #' @param groupIndex Integer or string. A group of electrodes to show together in a different color. If NULL(default), a...
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#========================================= # GENERAL COGNITIVE FUNCTION (g) #========================================= # COHORT: # Lothian Birth Cohort 1936 (LBC1936) wave 2 # MODEL: # - Structural Equation Modeling (SEM) using lavaan # - Single latent factor (g) loading onto all cognitive tests # - Resid...
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setwd("~/Documents/yu_lab/kernels_in_GP/Kick_data/") library(tidyverse) library(tensorflow) tf$config$list_logical_devices() library(keras3) library(kerastuneR) library(abind) HyperModel <- PyClass( "HyperModel", inherit = HyperModel_class(), list( build = function(self, hp) { clear_session(free_m...
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setwd("~/Documents/yu_lab/kernels_in_GP/Kick_data/") library(tidyverse) library(multcomp) source("src/scales.R") ref_pcs <- read_csv("processed/reference_sorted.csv", show_col_types = FALSE) y <- scale(ref_pcs$GrainYield[ref_pcs$Set == "Train"]) yc <- attr(y, "scaled:center") ys <- attr(y, "scaled:scale") ref_pcs <...
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--- title: "Fig 3 Example Coherence Plot" output: html_document date: "2024-11-20" --- ```{r setup, include=FALSE} knitr::opts_chunk$set( echo = FALSE, # don't print the code chunk warning = FALSE, # don't print warnings message = FALSE, # don't print messages fig.width = 8, # set default width of figures ...
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setwd("~/Documents/yu_lab/kernels_in_GP/Kick_data/") library(tidyverse) library(tensorflow) tf$config$list_logical_devices() library(keras3) library(kerastuneR) library(abind) HyperModel <- PyClass( "HyperModel", inherit = HyperModel_class(), list( build = function(self, hp) { clear_session(free_m...
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setwd("~/Documents/yu_lab/kernels_in_GP/Kick_data/") library(tidyverse) library(tensorflow) tf$config$list_logical_devices() library(keras3) library(kerastuneR) library(abind) HyperModel <- PyClass( "HyperModel", inherit = HyperModel_class(), list( build = function(self, hp) { clear_session(free_m...
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setwd("~/Documents/yu_lab/kernels_in_GP/Kick_data/") library(tidyverse) library(tensorflow) tf$config$list_logical_devices() library(keras3) library(kerastuneR) library(abind) HyperModel <- PyClass( "HyperModel", inherit = HyperModel_class(), list( build = function(self, hp) { clear_session(free_m...
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testthat::context("assert pipeline output equal to example from MS-EmpiRe R package") msdap::enable_log(FALSE) ######################################################## generate results ######################################################## ### example dataset and application of MS-EmpiRe following the documentatio...
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# %% Sys.setenv("OMP_NUM_THREADS" = 32) Sys.setenv("OPENBLAS_NUM_THREADS" = 32) Sys.setenv("MKL_NUM_THREADS" = 32) Sys.setenv("VECLIB_MAXIMUM_THREADS" = 32) Sys.setenv("NUMEXPR_NUM_THREADS" = 32) library(Seurat) library(SeuratObject) library(DESeq2) library(ggplot2) library(scales) library(qs) library(dplyr) path_dat...
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# Analyse the sleep trace of flies listed in metadata files under metadata/ library(data.table) library(parallel) library(behavr) library(digest) if(!file.exists("paths.txt")) { stop("Please make a file called paths.txt with the format: root,cache path_to_root,path_to_cache") } paths <- read.table("paths.txt", ...
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##################################### # Estimate metacognitive efficiency (Mratio) at the group level # # Adaptation in R of matlab function 'fit_meta_d_mcmc_group.m' # by Steve Fleming # for more details see Fleming (2017). HMeta-d: hierarchical Bayesian # estimation of metacognitive efficiency from confidence rating...
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## The following R code enables the generation of a pie chart to represent the proportions of immuno-positive and immuno-negative neurons. ## Sample data preparation neuron_data <- data.frame( ## Create a data frame to hold the counts of immuno-positive and immuno-negative neurons Immuno_positive = c(155...
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library(ggplot2) library(dplyr) library(cowplot) library(here) generate_boxplots <- function(input_data, X, Y, min,max){ data<-as.data.frame(input_data) #Ensure correct ordering of levels #data$Genotype <- data$SLC_Genotype #data$SLC_Genotype <- factor(data$SLC_Genotype, levels = c("WT", "HET", "MUT")) g...
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setwd("~/Documents/yu_lab/kernels_in_GP/Kick_data/") require(tidyverse) require(keras3) require(kerastuneR) HyperModel <- PyClass( "HyperModel", inherit = HyperModel_class(), list( build = function(self, hp) { clear_session(free_memory = TRUE) model <- keras_model_sequential(input_shape = c(17...
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##' This implements the SVDimpute algorithm as proposed by Troyanskaya ##' et al, 2001. The idea behind the algorithm is to estimate the ##' missing values as a linear combination of the \code{k} most ##' significant eigengenes. ##' ##' Missing values are denoted as \code{NA}. It is not recommended ##' to use this fun...
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#' Import a label-free proteomics dataset from a peptide-level Biobase ExpressionSet object #' #' provided mostly for compatability with results from prior bioinformatic analyses, as it is preferred to import raw data files. #' #' @param eset a Biobase ExpressionSet containing peptide data #' @param column_fdata_prot...
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setwd("~/Documents/yu_lab/kernels_in_GP/Kick_data/") library(tidyverse) library(keras3) library(abind) source("src/scale2.R") ### Reproducibly select sub-model runs ---------------------------------------- seeds <- c(758069L, 929940L, 591511L, 882475L, 961222L, 780783L, 139364L, 220106L, 841340L, 252774...
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#' Estimate cellular composition with error #' #' Estimate the cellular composition from a DNA methylation profile and #' calculate the CETYGO score error metric associated with this estimate. #' #' @param YIN a matrix of DNA methylation levels from the samples that require #' cell composition to be estimated. #' @para...
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setwd("~/Documents/yu_lab/kernels_in_GP/Kick_data/") library(tidyverse) library(rrBLUP) library(parallel) ### Load the hybrid marker matrix --------------------------------------------- # From Lopez-Cruz et al. (2023) X <- read_csv("../../genomes2fields_curated/data/data_g2f/GENO.csv", show_col_types = FALSE) x_taxa...
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#' Check for separation of count distributions by variables #' #' Check the count distributions for each nhood according to a test #' variable of interest. This is important for checking if there is separation #' in the GLMM to inform either nhood subsetting or re-computation of the #' NN-graph and refined nhoods. #' @...
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# Nearest.r # Includes hemisphere and monkey info # Absolute value of NEAR is the criterion distance # NEGATIVE value means exclude the originals - give JUST the added ones # Warning: some LIP/PRR do not have depths, so will not be in LIP & PRR # If we append only a single monkey as a last column, then 'base' se...
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library(tidyverse) library(synExtra) library(synapser) library(powerjoin) # Select ROSMAP samples that use rRNA depletion instead of poly-A enrichment # in library prep. Can't quantify repeat transcripts in samples prepared # using poly-A enrichment synLogin() syn <- synDownloader("~/data", .cache = TRUE) rosmap_cl...
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#06_enrichment_analysis.R rm(list=ls()) library(dplyr) library(ggplot2) #1.SNP-based PheWAS---- #41 lead SNP SNP_lead=read.table('./GWAS/pheWAS/26_Topic_lead_SNP.txt') SNP=list() for(i in SNP_lead$V1){ if(file.exists(paste0('./GWAS/pheWAS/',i,'.csv'))){ SNP[[i]]=read.csv(paste0('./GWAS/pheWAS/',i,'.csv'),header...
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# Load packages ----------------------------------- library(Seurat) library(tidyverse) library(enrichR) library(patchwork) library(glue) library(Matrix) library(DropletUtils) library(SeuratWrappers) library(dorothea) library(org.Hs.eg.db) library(clusterProfiler) library(DOSE) library(qs) library(enrichplot) library(wr...
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setwd("~/Documents/yu_lab/kernels_in_GP/Kick_data/") library(tidyverse) library(RSpectra) library(tensorEVD) ### The reference table has the pedigree and environment of each data record -- ref <- read_csv("processed/reference_sorted.csv", show_col_types = FALSE) ug <- unique(ref$Pedigree) ue <- unique(ref$Environmen...
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context("Testing buildGraph function") library(miloR) ### Set up a mock data set using simulated data library(SingleCellExperiment) library(scran) library(scater) library(irlba) library(MASS) library(mvtnorm) set.seed(42) r.n <- 1000 n.dim <- 50 block1.cells <- 500 # select a set of eigen values for the covariance ma...
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# Nearest.r # Includes hemisphere and monkey info # Absolute value of NEAR is the criterion distance # NEGATIVE value means exclude the originals - give JUST the added ones # Warning: some LIP/PRR do not have depths, so will not be in LIP & PRR # If we append only a single monkey as a last column, then 'base' se...
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--- title: "Granger Plots" output: html_document date: "2025-02-18" --- ```{r setup, include=FALSE} ## libraries ## library(tidyverse) library(ggplot2) library(lmerTest) library(doParallel) library(parallel) library(foreach) library(here) library(fs) library(lmtest) library(scales) library(ggthemr) library(RColorBrewer...
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#!/usr/bin/env Rscript # Run this script in r-linda environment library(broom.mixed) library(dplyr) library(lme4) library(lmerTest) library(optparse) library(tidyverse) library(vroom) ## ## READ TABLES ## df_meta <- read.table( "../seq-meta-data-tidy/outputs/mapping/meta-data-bcm-all-sequencing.tsv", sep = ...
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library(here) library(tidyverse) library(cowplot) library(ggplot2) ### Establish location --- here::i_am("src/PFF/PFF_Correlate_DAT_with _Rotarod.R") ### Read in input files --- PFF_rotarod <- read.csv(here("data/PFF/PFF Rotarod - PFF_Rotarod_Analysis.csv")) PFF_rotarod <- PFF_rotarod %>% filter(Day=="one") %>% d...
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## libraries ## library(tidyverse) library(here) library(fs) library(scales) library(brms) ## load data ## conn_df <- read_csv(path(here(), "combined_ghost_connectivity_newsubs.csv")) ## split the dlpfc electrodes into MFG and SFG ## regions_df <- read_csv(path(here(), "mni_coordinates_all_subs_with_detailed_re...
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#' Parekh et al. 2016: Gene Expression Matrices #' #' 250 ng of Universal Human Reference RNA (UHRR; Agilent Technologies; catalog #740000) and ERCC spike-in control mix I (Life Technologies) were used and cDNA was synthesized as described in the Smart-Seq2 protocol from Picelli et al. 2013.\cr #' Base-calls were perf...
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## libraries ## library(tidyverse) library(here) library(fs) library(scales) library(brms) ## load data ## conn_df <- read_csv(path(here(), "combined_ghost_connectivity_newsubs.csv")) ## split the dlpfc electrodes into MFG and SFG ## regions_df <- read_csv(path(here(), "mni_coordinates_all_subs_with_detailed_re...
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library(here) library(ggplot2) library(rlang) library(rstatix) library(nlme) library(cowplot) library(ggbeeswarm) library(ggpubr) library(ggsignif) library(knitr) library(here) here::i_am("Rscripts/MPTP/MPTP_Open_Field.R") data <- readr::read_csv(here("Analysis_Files", "MPTP","MPTP_Open_Field.csv")) data$SLC_Genotyp...
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# --- mr_T1D_to_PD.R --- # One-shot bidirectional MR: T1D (exposure) -> PD (outcome) # IVs: P < 5e-8, F >= 10; LD clumping r2 < 0.001 (other clump params default) library(TwoSampleMR) library(data.table) library(openxlsx) library(genetics.binaRies) setDTthreads(threads = 0) # ========= Paths (edit if needed) =======...
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setwd("~/Documents/yu_lab/kernels_in_GP/Kick_data/") library(tidyverse) ref <- read_csv("processed/reference_sorted.csv", show_col_types = FALSE) y <- scale(ref$GrainYield[ref$Set == "Train"]) yc <- attr(y, "scaled:center") ys <- attr(y, "scaled:scale") rm(ref, y); gc() ref_pcs <- read_csv("processed/reference_sort...
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setwd("~/Documents/yu_lab/kernels_in_GP/Kick_data/") library(tidyverse) library(abind) source("src/scale2.R") # For reproducibility: set.seed(620200) ref <- read_csv("processed/reference_sorted.csv", show_col_types = FALSE) # Number of unique environments in each set (distinguished by site-year) ue <- ref %>% ...
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# doGroupPower.r (Seul Ah Kim) # # This is a modified version of doPower.r to run with PowerVsDistance.r in R/ subdirectory. ########################################################################### # GRAB PARAMETERS # ########################################################################### ...
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library(here) library(tidyr) library(dplyr) library(ggplot2) library(cowplot) library(nlme) library(ggpubr) setwd("/Users/rochellelai/Documents/JacobsGit/slcproject/PFF_Microbiome/alpha_diversity/") # here::i_am("PFF_Microbiome_RProj/Alpha_Diversity.R") ### Read data frames # Choose one type of data set below # JEJU...
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## libraries ## library(tidyverse) library(here) library(fs) library(scales) library(brms) ## load data ## conn_df <- read_csv(path(here(), "data_mount", "remote", "pacman", "connectivity", "ieeg", "imcoh_ppc_pli", "combined_ghost_connectivity_newsubs.csv")) ## split the dlpfc electrodes into MFG and SFG ## regions...
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safeBinomTest = function(x, y) { if (y == 0) { output = list(estimate = NA, conf.int = c(NA, NA)) } else { output = binom.test(x, y, p = 0.5, alternative = "two.sided", conf.level = 1 - SIG_THRESHOLD) } output } safeFisherTest = function(x, y, z, w) { if (x + y == 0 || x + z == 0 || y + w == 0 || z ...
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DeepScore <- function(hidden_nodes, common_features, n_labels, epochs=10, batch_size=32, activation="relu", dropout=TRUE, dropout_rate=0.2, batchnorm=TRUE, lr=0.001, weight_reg=TRUE, l1=0, l2=0) { ds <- list( model = NULL, common_featur...
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## libraries ## library(tidyverse) library(here) library(fs) library(scales) library(brms) ## load data ## conn_df <- read_csv(path(here(), "data_mount", "remote", "pacman", "connectivity", "ieeg", "imcoh_ppc_pli", "combined_ghost_connectivity_newsubs.csv")) ## split the dlpfc electrodes into MFG and SFG ## region...
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```{r} source(here::here("src/init.R")) ``` <!----------------------------------------------------------> <!----------------------------------------------------------> # I. Data ```{r} data_dict <- load_data_dict() (supplementary_data <- load_supplementary_data()) # Use reprocess = TRUE to re-process the data and r...
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library(ggplot2) library(dplyr) library(cowplot) library(here) library(tidyr) library(ggbeeswarm) ## Environment -- here::i_am("Rscripts/Figure_S3_MPTP_Behaviors.R") ## Functions -- generate_boxplots <- function(input_data, X, Y, min,max){ data<-as.data.frame(input_data) #Ensure correct ordering of levels #dat...
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--- title: "Patient models - heatmap of expression" output: html_document author: "Daeun Jeong/Sara Danielli" date: "2025-04-21" --- ```{r} # Load packages ----------------------------------- rm(list = ls()) library(data.table) library(tidyverse) library(R.utils) library(ggpubr) library(dplyr) library(Seurat) librar...
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##' This is a simple estimator for the optimal number of componets ##' when applying PCA or LLSimpute for missing value estimation. No ##' cross validation is performed, instead the estimation quality is ##' defined as Matrix[!missing] - Estimate[!missing]. This will give a ##' relatively rough estimate, but the numbe...
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#' This function trains, fits and evaluates a deep neural network (DNN) model. #' #' This function creates a DNN model from the reference dataset (scRNA-seq) by using the keras package. #' @param out The output of the ds_split_data_encoder function. The input data used to train the DNN model. #' @param hnodes The numbe...
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Co_Embeddinglog<-function(snATAC,snRNA,name){ library(parallel) library(Seurat) library(dplyr) library(ggplot2) out_name1=paste0(name,".log") #1、downsampling from each cluster or each Subclass #2、Integrate snATAC & snRNA print(snATAC) print(snRNA) #choose the intersection genes gene=intersect(rownames(snATAC...
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setwd("~/Documents/yu_lab/kernels_in_GP/Kick_data/") library(tidyverse) library(multcomp) res <- read_csv("results/metrics_all_env.csv", show_col_types = FALSE) |> filter(Data %in% c("G", "A")) |> dplyr::select(-Data) |> mutate(Model = if_else(Model == "DNN-CO", "ReLU", Model)) res2 <- list.files("09.pc_com...
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# spectragram.r # first run power.r to get mdata (ReadData.r) (mean, baseline-removed) # data[times, bands, stacks] # BANDS.SEQ frequencies (total of BAND) # 1:dim(data)[1] time points # dimnames(data)[[2]] another way to get these if (!exists("mdata")) stop("Must run doAll.r, with ALIGN='go', class='', all els...
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## libraries ## library(tidyverse) library(here) library(fs) library(scales) library(brms) ## load data ## conn_df <- read_csv(path(here(), "data_mount", "remote", "pacman", "connectivity", "ieeg", "imcoh_ppc_pli", "combined_ghost_connectivity_newsubs.csv")) ## split the dlpfc electrodes into MFG and SFG ## regio...
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--- title: "P3 latency" output: html_document --- ```{r include = FALSE} # clear old outputs if(dir.exists(file.path("../output/p3_latency"))) { unlink("../output/p3_latency", recursive = TRUE) } output_dir <- file.path("../output/p3_latency") dir.create(output_dir) nice_tables_file <- paste0(output_dir, "/nic...
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--- title: "MMN latency" output: html_document --- ```{r include = FALSE} # clear old outputs if(dir.exists(file.path("../output/mmn_latency"))) { unlink("../output/mmn_latency", recursive = TRUE) } output_dir <- file.path("../output/mmn_latency") dir.create(output_dir) nice_tables_file <- paste0(output_dir, "...
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# Step 5: Test data and future directions ## Public datasets The pipeline with default settings (smoothing and color clusters of k-means in VNS function) used for the [Maynard, Collado-Torres et al, Nature Neuroscience, 2021](https://doi.org/10.1038/s41593-020-00787-0) LIBD data has been applied on the [public datase...
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context("Test buildFromAdjacency function") library(miloR) ### Set up a mock data set using simulated data library(SingleCellExperiment) library(scran) library(scater) library(irlba) library(MASS) library(mvtnorm) library(miloR) set.seed(42) r.n <- 1000 n.dim <- 50 block1.cells <- 500 # select a set of eigen values f...
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#### epiTOC2.R #### Author: Andrew E Teschendorff (a.teschendorff@ucl.ac.uk) #### Date: 8th Apr.2019 #### Copyright 2019 Andrew Teschendorff #### Copyright permission: epiTOC2 is free software: you can redistribute it and/or modify it under the terms of the GNU General Public License version-3 as published by the Free...
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library(sjPlot) library(broom.mixed) # for tidy() library(dplyr) library(emmeans) library(lme4) library(lmerTest) library(ggplot2) library(moments) library(ggeffects) library(robustlmm) library(glmmTMB) library(patchwork) library(forcats) library(scales) df <- read.csv("E:\\work\\q_backup_06_03_2025\\projects\\i...
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library(ggplot2) library(dplyr) library(ggplot2) library(data.table) run_subtype <- T n_models <- 4 mode <- '_converge' resdir <- 'results' batch_suffix <- '_with_hidden_batch_' data_dir <- './data' cts <- c('Microglia', 'Astrocyte', 'Inhibitory Neurons', 'Oligodendrocytes', 'cux2+', 'cux2-', 'OPCs') summary <- func...
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library(ggplot2) library(vegan) library(dplyr) library(rlang) library(cowplot) library(viridis) library(here) ## Environment -- here::i_am("Rscripts/Figure_Correlate_PFF_Rotarod.R") metadata <- read.table("Analysis_Files/PFF/PFF_Microbiome/starting_files/PFF_Mapping.tsv",header=TRUE) counts <- read.table("Analysis_Fi...
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library(data.table) library(infercnv) library(tidyverse) library(crayon) library(ape) library(readxl) options(scipen = 100) base_dir <- "/n/scratch/users/s/sad167/EPN/scRNAseq" resources_dir <- file.path(base_dir, 'scripts/resources') ext_ctrl <- file.path(resources_dir, 'ctrl_data') source(file.path(resources_dir, ...
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##' Later ##' @param nlnet the nlnet ##' @param trainIn training data ##' @param trainOut fitted data ##' @return derror ##' @author Henning Redestig, Matthias Scholz derrorHierarchic <- function(nlnet, trainIn, trainOut) { weights <- nlnet@weights$current() netDim <- dim(nlnet@net) if(nlnet@inverse) { num...
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#' Training HD algorithm using the NHANES III (1988 - 1994) and projecting into NHANES IV (1999 - 2018) dataset. For this function, NHANES III included men and women who are between the ages of 20 and 30, and have observe biomarker data within clinically acceptable distributions. #' #' @title hd_nhanes #' @description ...
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### Approach Theta Coherence ~ Time ### ## libraries ## library(tidyverse) library(ggplot2) library(doParallel) library(parallel) library(foreach) library(here) library(fs) library(scales) library(brms) ## load data ## conn_df <- read_csv(path(here(), "munge", "combined_ghost_connectivity_newsubs.csv")) ## split the...
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### Approach Theta Coherence ~ Time ### ## libraries ## library(tidyverse) library(ggplot2) library(doParallel) library(parallel) library(foreach) library(here) library(fs) library(scales) library(brms) ## load data ## conn_df <- read_csv(path(here(), "munge", "combined_ghost_connectivity_newsubs.csv")) ## split the...
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surv_res = function (dat, agevar, covar) { covars = paste(covar, collapse = "+") cox = list() for (i in agevar) { form = formula(paste("survival::Surv(time,status)~", i, "+", covars, sep = "")) cox[[i]] = survival::coxph(form, data = dat) }; rm(i) res = lapply(cox,summary) table = as.data.fra...
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#' Import a label-free proteomics dataset from Peaks #' #' @param filename a features.csv file exported by Peaks #' @param collapse_peptide_by if multiple data points are available for a peptide in a sample, at what level should these be combined? options: "sequence_modified" (recommended default), "sequence_plain", ""...
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#03_GWAS_for_ES-Ana.R rm(list=ls()) #1.mh plot---- results_log <- data.table::fread("./01_taxa/all/Topic/lm.topic.assoc.linear", head=TRUE) results_log=results_log[,c('SNP','CHR','BP','P')] a1=subset(results_log,-log10(P)>2)#60872 a1=a1[,c('SNP','CHR','BP','P')] dd2=read.table('./01_taxa/all/Topic/clumped_results.c...