Public text-only card: DOSE v1.0, 2466 rows, no audio
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README.md
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---
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license: cc-by-4.0
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task_categories:
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- text-to-speech
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- audio-classification
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language:
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- en
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tags:
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- text-to-speech
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- tts
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- pronunciation
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- healthcare
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- pharma
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- drug-names
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- benchmark
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pretty_name: DOSE
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size_categories:
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- 1K<n<10K
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configs:
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- config_name: default
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dataset_info:
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features:
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- name: drug
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dtype: string
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- name: name_type
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dtype:
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class_label:
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names:
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'0': brand
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'1': generic
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- name: sentence
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dtype: string
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- name: ground_truth_ipa
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dtype: string
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- name: system_key
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dtype: string
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- name: system_name
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dtype: string
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- name: heard_ipa
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dtype: string
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- name: score
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dtype: int32
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- name: passed
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dtype: bool
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- name: has_audio
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dtype: bool
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splits:
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- name: train
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num_bytes: 598164
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num_examples: 2466
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download_size: 54195
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dataset_size: 598164
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---
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# DOSE v1: Drug-name Oral Synthesis Evaluation
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**Can your voice model say retatrutide?**
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DOSE is a benchmark measuring how accurately text-to-speech (TTS) systems
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pronounce pharmaceutical drug names. It covers
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rather than spoken in isolation.
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## Why this matters
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row = ds[0]
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print(row["drug"], row["system_name"], row["score"], row["passed"])
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row["audio"] # decoded automatically -> {"array": np.ndarray, "sampling_rate": int}
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```
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Filter to
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```python
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synthio_only = ds.filter(lambda r: r["system_key"] == "synthio_rxpronounce")
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generic_names = ds.filter(lambda r: r["name_type"] == "generic")
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```
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Recompute the leaderboard
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```python
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import pandas as pd
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- **274 drug names**: 128 traditional (established) + 146 new (recently
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approved) names.
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- **Brand and generic/INN names** (`name_type` column)
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- **9 TTS systems** evaluated on each name, each using its current
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flagship model: ElevenLabs, OpenAI, Google (Gemini), Deepgram,
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Microsoft Azure, Cartesia (two model versions), xAI, and Synthio
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RxPronounce.
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- **2,461 scored utterances** total (one row per drug x system, minus a
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handful of deterministic provider-side generation failures).
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- Every system reads the **exact same clinical sentence** containing the
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drug name, with no special pronunciation hints given to any system.
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##
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Each drug’s reference comes from public
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## Columns
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|---|---|---|
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| `drug` | string | Drug name (brand or generic/INN) |
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| `name_type` | class label | `brand` or `generic` |
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| `sentence` | string | The clinical sentence read aloud
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| `ground_truth_ipa` | string | Correct pronunciation (informal phonetic spelling) |
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| `system_key` | string | Machine-readable system identifier |
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| `system_name` | string | Human-readable TTS system name |
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| `heard_ipa` | string | Phonetic transcription of what the system
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| `score` | int (0
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| `passed` | bool | `score >= 4` |
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| `
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## Leaderboard (overall pass rate, score >= 4)
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## Submit your model
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## Citation
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```bibtex
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@misc{synthio2026dosev1,
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title = {DOSE v1: Drug-name Oral Synthesis Evaluation},
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author = {Pari, Rohit Gangadhar and {Synthio Labs}},
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year = {2026},
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url = {https://www.synthiolabs.com/synthio-dose-benchmark}
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---
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license: cc-by-4.0
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task_categories:
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- text-to-speech
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language:
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- en
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tags:
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- text-to-speech
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+
- tts
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- pronunciation
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+
- healthcare
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- pharma
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- drug-names
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- benchmark
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pretty_name: DOSE v1.0 (Drug-name Oral Synthesis Evaluation)
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size_categories:
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- 1K<n<10K
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configs:
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- config_name: default
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data_files:
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- split: train
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path: data/train-*.parquet
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---
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# DOSE v1.0: Drug-name Oral Synthesis Evaluation
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**Can your voice model say retatrutide?**
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DOSE is a benchmark measuring how accurately text-to-speech (TTS) systems
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+
pronounce pharmaceutical drug names. It covers established brands,
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+
newly-approved names, and generic/INN names, each tested inside a real
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clinical sentence rather than spoken in isolation.
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**Version: DOSE v1.0.** Live leaderboard and five public audio samples:
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https://www.synthiolabs.com/synthio-dose-benchmark
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This public dataset is **text-only** (sentences, reference pronunciations,
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per-system scores). The evaluation audio is not released here. Request the
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full audio set at [rohit@synthiolabs.com](mailto:rohit@synthiolabs.com?subject=DOSE%20full%20audio%20request).
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## Why this matters
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row = ds[0]
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print(row["drug"], row["system_name"], row["score"], row["passed"])
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```
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Filter to one system, failures, or generic names:
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```python
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synthio_only = ds.filter(lambda r: r["system_key"] == "synthio_rxpronounce")
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generic_names = ds.filter(lambda r: r["name_type"] == "generic")
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```
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Recompute the leaderboard:
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```python
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import pandas as pd
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- **274 drug names**: 128 traditional (established) + 146 new (recently
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approved) names.
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+
- **Brand and generic/INN names** (`name_type` column).
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- **9 TTS systems** evaluated on each name.
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- **2,466 scored utterances** (274 names × 9 systems). Five of those are
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provider-side generation failures recorded as score 0 with no audio.
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- Every system reads the **exact same clinical sentence** containing the
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drug name, with no special pronunciation hints given to any system.
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## How DOSE is scored
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**Reference pronunciations.** Each drug’s reference comes from public
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pharmaceutical sources, including labels, manufacturer materials, and
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established medical references. It is then checked against spoken clinical
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usage so the target reflects the accepted pronunciation — not a model’s
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guess.
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**Judge.** Each system’s recording is scored 0–5 against that same
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reference by automated audio comparison. Several independent judgments are
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combined into one result; **4 or higher counts as a pass**. Human
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reviewers are not in the scoring loop.
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## Columns
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|---|---|---|
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| `drug` | string | Drug name (brand or generic/INN) |
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| `name_type` | class label | `brand` or `generic` |
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| `sentence` | string | The clinical sentence read aloud |
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| `ground_truth_ipa` | string | Correct pronunciation (informal phonetic spelling) |
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| `system_key` | string | Machine-readable system identifier |
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| `system_name` | string | Human-readable TTS system name |
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| `heard_ipa` | string | Phonetic transcription of what the system said |
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| `score` | int (0–5) | Judged pronunciation accuracy |
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| `passed` | bool | `score >= 4` |
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| `has_audio` | bool | False for the five provider-side generation failures |
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## Leaderboard (overall pass rate, score >= 4)
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## Submit your model
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Email us at [rohit@synthiolabs.com](mailto:rohit@synthiolabs.com?subject=DOSE%20model%20submission)
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to submit a model for evaluation, or to request the full evaluation audio.
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## Citation
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```bibtex
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@misc{synthio2026dosev1,
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title = {DOSE v1.0: Drug-name Oral Synthesis Evaluation},
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author = {Pari, Rohit Gangadhar and {Synthio Labs}},
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year = {2026},
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url = {https://www.synthiolabs.com/synthio-dose-benchmark}
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