{
"tasks": [
{
"task_id": "amine-borane-arylation-bases",
"doi": "10.1038/s41586-025-09725-1",
"title": "Deaminative cross-coupling of amines by boryl radical β-scission",
"authors": [
"Zhenhua Zhang",
"Giovanni Lonardi",
"Thomas Sephton",
"Yusuf C. Guersoy",
"Chiara Stavagna",
"Giovanni V. A. Lenardon",
"Massimo Bietti",
"Daniele Leonori"
],
"journal": "Nature",
"url": "https://www.nature.com/articles/s41586-025-09725-1"
},
{
"task_id": "amine-borane-divergent-functionalization-ranking",
"doi": "10.1038/s41586-025-09725-1",
"title": "Deaminative cross-coupling of amines by boryl radical β-scission",
"authors": [
"Zhenhua Zhang",
"Giovanni Lonardi",
"Thomas Sephton",
"Yusuf C. Guersoy",
"Chiara Stavagna",
"Giovanni V. A. Lenardon",
"Massimo Bietti",
"Daniele Leonori"
],
"journal": "Nature",
"url": "https://www.nature.com/articles/s41586-025-09725-1"
},
{
"task_id": "bora-butenolide-conjugated-substrates",
"doi": "10.1038/s41467-025-60052-5",
"title": "Expedient access to bora-butenolide bioisosteres by counteranion-mediated trans-hydroboration of alkynes",
"authors": [
"Yuan-Wen Liu",
"Yu Liu",
"Yanting Zheng",
"Mengfan Zhang",
"Meng-En Ren",
"Peiyu Hua",
"Jie Han",
"Alois Fürstner",
"Hongming Jin"
],
"journal": "Nature Communications",
"url": "https://www.nature.com/articles/s41467-025-60052-5"
},
{
"task_id": "dialuminum-quinoline-catalyst-loading-yield",
"doi": "10.1038/s41467-025-63460-9",
"title": "Regio- and chemoselective catalytic partial transfer hydrogenation of quinolines by dinuclear aluminum species",
"authors": [
"Xufang Liu",
"Arseni Kostenko",
"Matthew M. D. Roy",
"Tobias Weng",
"Shigeyoshi Inoue"
],
"journal": "Nature Communications",
"url": "https://www.nature.com/articles/s41467-025-63460-9"
},
{
"task_id": "benzothiophene-photodimer-solvent-yield",
"doi": "10.1038/s41467-026-75078-6",
"title": "Visible Light-Induced Intermolecular Dearomatization for Constructing Angularly Fused Tetracyclic Scaffolds",
"authors": [
"Fan Lin",
"Ting-Ting Song",
"Li-Ming Zhang",
"Zhi-Yuan Ding",
"Yilitabaier Julaiti",
"Yanhua Lu",
"Boshun Wan",
"Yaguang Sun",
"Qing-An Chen"
],
"journal": "Nature Communications",
"url": "https://www.nature.com/articles/s41467-026-75078-6"
},
{
"task_id": "copper-allylic-amination-additive-yield",
"doi": "10.1038/s41467-025-64951-5",
"title": "Light-driven radical copper-catalyzed allylic amination via allylic copper intermediates",
"authors": [
"Hang Luo",
"Yupeng Yang",
"Yunpeng Ma",
"Fangnian Yu",
"Min Gao",
"Shizhao Xu",
"Huawei Ju",
"Yang Li",
"Kaifeng Wu",
"Luqing Lin"
],
"journal": "Nature Communications",
"url": "https://www.nature.com/articles/s41467-025-64951-5"
},
{
"task_id": "arene-acid-coupling-loading",
"doi": "10.1038/s41586-025-08887-2",
"title": "Generalizing arene C–H alkylations by radical–radical cross-coupling",
"authors": [
"Johannes Großkopf",
"Chawanansaya Gopatta",
"Robert T. Martin",
"Alexander Haseloer",
"David W. C. MacMillan"
],
"journal": "Nature",
"url": "https://www.nature.com/articles/s41586-025-08887-2"
},
{
"task_id": "pyrazole-hydroamination-component-ranking",
"doi": "10.1038/s41586-026-10263-7",
"title": "Markovnikov hydroamination of terminal alkenes by phosphine redox catalysis",
"authors": [
"Flora Fan",
"Kassandra F. Sedillo",
"Alexander J. Maertens",
"Abigail G. Doyle"
],
"journal": "Nature",
"url": "https://www.nature.com/articles/s41586-026-10263-7"
},
{
"task_id": "arene-acid-additional-catalysts-ranking",
"doi": "10.1038/s41586-025-08887-2",
"title": "Generalizing arene C–H alkylations by radical–radical cross-coupling",
"authors": [
"Johannes Großkopf",
"Chawanansaya Gopatta",
"Robert T. Martin",
"Alexander Haseloer",
"David W. C. MacMillan"
],
"journal": "Nature",
"url": "https://www.nature.com/articles/s41586-025-08887-2"
},
{
"task_id": "rna-aminoacylation-strand-architecture-ranking",
"doi": "10.1038/s41586-025-09388-y",
"title": "Thioester-mediated RNA aminoacylation and peptidyl-RNA synthesis in water",
"authors": [
"Jyoti Singh",
"Benjamin Thoma",
"Daniel Whitaker",
"Max Satterly Webley",
"Yuan Yao",
"Matthew W. Powner"
],
"journal": "Nature",
"url": "https://www.nature.com/articles/s41586-025-09388-y"
},
{
"task_id": "rna-aminoacylation-donor-template-ranking",
"doi": "10.1038/s41586-025-09388-y",
"title": "Thioester-mediated RNA aminoacylation and peptidyl-RNA synthesis in water",
"authors": [
"Jyoti Singh",
"Benjamin Thoma",
"Daniel Whitaker",
"Max Satterly Webley",
"Yuan Yao",
"Matthew W. Powner"
],
"journal": "Nature",
"url": "https://www.nature.com/articles/s41586-025-09388-y"
},
{
"task_id": "alkene-transfer-conditions-ranking",
"doi": "10.1038/s41586-025-09159-9",
"title": "One-carbon homologation of alkenes",
"authors": [
"Marcus C. Grocott",
"Matthew J. Gaunt"
],
"journal": "Nature",
"url": "https://www.nature.com/articles/s41586-025-09159-9"
},
{
"task_id": "fluorene-dehydration-concentrations",
"doi": "10.1038/s41586-025-09490-1",
"title": "Robot-assisted mapping of chemical reaction hyperspaces and networks",
"authors": [
"Yankai Jia",
"Rafał Frydrych",
"Yaroslav I. Sobolev",
"Wai-Shing Wong",
"Bibek Prajapati",
"Daniel Matuszczyk",
"Yasemin Bilgi",
"Louis Gadina",
"Juan Carlos Ahumada",
"Galymzhan Moldagulov",
"Namhun Kim",
"Eric S. Larsen",
"Maxence Deschamps",
"Yanqiu Jiang",
"Bartosz A. Grzybowski"
],
"journal": "Nature",
"url": "https://www.nature.com/articles/s41586-025-09490-1"
},
{
"task_id": "azidopyridine-hydrolysis-condition-yield",
"doi": "10.1038/s41467-025-65313-x",
"title": "Formal pyridine meta-azidation and its application for the synthesis of diazepines, ring-fused δ-carbolines and 1,2,3-triazolylpyridines",
"authors": [
"Shu-Min Guo",
"Pengwei Xu",
"Constantin G. Daniliuc",
"Armido Studer"
],
"journal": "Nature Communications",
"url": "https://www.nature.com/articles/s41467-025-65313-x"
},
{
"task_id": "deutero-amination-reagent-solvent-yield",
"doi": "10.1038/s41467-025-57098-w",
"title": "Access to N-α-deuterated amino acids and DNA conjugates via Ca(II)-HFIP-mediated reductive deutero-amination of α-oxo-carbonyl compounds",
"authors": [
"Haoran Li",
"Yuwei Liu",
"Silin Zhang",
"Lei Ma",
"Zhongyi Zeng",
"Zhi Zhou",
"Vincent Gandon",
"Hongtao Xu",
"Wei Yi",
"Shengdong Wang"
],
"journal": "Nature Communications",
"url": "https://www.nature.com/articles/s41467-025-57098-w"
},
{
"task_id": "indolylmethanol-cycloaddition-volume-temperature-yield",
"doi": "10.1038/s41467-025-62035-y",
"title": "Atroposelective construction of axially chiral alkenylindole-fused nine-membered rings via catalytic asymmetric formal (4 + 5) cycloaddition",
"authors": [
"Si-Jia Liu",
"Xue Wang",
"Ji-Xiang Yang",
"Xian-Song Ao",
"Shao-Fei Ni",
"Yu-Chen Zhang",
"Feng Shi"
],
"journal": "Nature Communications",
"url": "https://www.nature.com/articles/s41467-025-62035-y"
},
{
"task_id": "mem-cyclopropene-phosphine-conditions-ranking",
"doi": "10.1038/s41586-025-09485-y",
"title": "Catalytic enantioselective synthesis of alkylidenecyclopropanes",
"authors": [
"Jonathan C. Golec",
"Dong-Hang Tan",
"Ken Yamazaki",
"Eveline H. Tiekink",
"Kirsten E. Christensen",
"Trevor A. Hamlin",
"Darren J. Dixon"
],
"journal": "Nature",
"url": "https://www.nature.com/articles/s41586-025-09485-y"
},
{
"task_id": "bcb-aldehyde-substrate-isolated-yield-ranking",
"doi": "10.1038/s41467-025-64399-7",
"title": "Organocatalytic enantioselective [2π + 2σ] cycloaddition reactions of bicyclo[1.1.0]butanes with α,β-unsaturated aldehydes",
"authors": [
"Yi-Xiang Geng",
"Teng-Fei Xiao",
"Dong Xie",
"Ming-Ming Li",
"Pan-Pan Zhou",
"Guo-Qiang Xu",
"Peng-Fei Xu"
],
"journal": "Nature Communications",
"url": "https://www.nature.com/articles/s41467-025-64399-7"
},
{
"task_id": "nitronate-addition-preparative-scope-ranking",
"doi": "10.1038/s41586-025-09905-z",
"title": "The asymmetric synthesis of an acyclic N-stereogenic amine",
"authors": [
"Chendan Zhu",
"Sayantani Das",
"Marie Sophie Sterling",
"Nobuya Tsuji",
"Spencer J. Léger",
"Frank Neese",
"Chandra Kanta De",
"Benjamin List"
],
"journal": "Nature",
"url": "https://www.nature.com/articles/s41586-025-09905-z"
},
{
"task_id": "oxetane-catalyst-pair-yields",
"doi": "10.1038/s41586-025-09813-2",
"title": "Accelerating the discovery of multicatalytic cooperativity",
"authors": [
"Marcus H. Sak",
"Richard Y. Liu",
"Eugene E. Kwan",
"Eric N. Jacobsen"
],
"journal": "Nature",
"url": "https://www.nature.com/articles/s41586-025-09813-2"
},
{
"task_id": "nitronate-addition-additional-catalyst-ranking",
"doi": "10.1038/s41586-025-09905-z",
"title": "The asymmetric synthesis of an acyclic N-stereogenic amine",
"authors": [
"Chendan Zhu",
"Sayantani Das",
"Marie Sophie Sterling",
"Nobuya Tsuji",
"Spencer J. Léger",
"Frank Neese",
"Chandra Kanta De",
"Benjamin List"
],
"journal": "Nature",
"url": "https://www.nature.com/articles/s41586-025-09905-z"
},
{
"task_id": "organoboron-absolute-fluorescence-yield-ranking",
"doi": "10.1038/s41467-025-64698-z",
"title": "Rhodium-catalyzed construction of boron-based point and axial chirality via asymmetric annulation of alkynylborons",
"authors": [
"Xiaohan Zhu",
"Yue Shi",
"Jing Li",
"Haonan Peng",
"Mengxia Gong",
"Wei Zhou",
"Fen Wang",
"Genping Huang",
"Xingwei Li",
"Yu Fang"
],
"journal": "Nature Communications",
"url": "https://www.nature.com/articles/s41467-025-64698-z"
},
{
"task_id": "fmoc-lysine-carbon-site-shift-ranking",
"doi": "10.1038/s41557-026-02112-x",
"title": "KDM3A catalyses the oxidation of acetyl-lysine to hydroxyacetyl-lysine on histone H3K9",
"authors": [
"Roman Belle",
"John-Paul Bukowski",
"Rachel Schiller",
"Ronald Cutler",
"Eidarus Salah",
"Robert S. Dawber",
"Anthony Tumber",
"Joanna Bonnici",
"Jessica D. Kindrick",
"Loane Serrano",
"Patrick Rabe",
"Catrine Johansson",
"Marie-Hélène Ruchaud",
"Richard J. Hopkinson",
"William D. Figg, Sr",
"Paul E. Brennan",
"David R. Mole",
"Simone Sidoli",
"Akane Kawamura",
"Christopher J. Schofield"
],
"journal": "Nature Chemistry",
"url": "https://www.nature.com/articles/s41557-026-02112-x"
},
{
"task_id": "pyrrolidine-aza-shono-components-ranking",
"doi": "10.1038/s41586-024-08373-1",
"title": "Light-harvesting microelectronic devices for wireless electrosynthesis",
"authors": [
"Bartosz Górski",
"Jonas Rein",
"Samantha Norris",
"Yanxin Ji",
"Paul L. McEuen",
"Song Lin"
],
"journal": "Nature",
"url": "https://www.nature.com/articles/s41586-024-08373-1"
},
{
"task_id": "benzoxazole-electroamination-library-ranking",
"doi": "10.1038/s41586-024-08373-1",
"title": "Light-harvesting microelectronic devices for wireless electrosynthesis",
"authors": [
"Bartosz Górski",
"Jonas Rein",
"Samantha Norris",
"Yanxin Ji",
"Paul L. McEuen",
"Song Lin"
],
"journal": "Nature",
"url": "https://www.nature.com/articles/s41586-024-08373-1"
},
{
"task_id": "rhodium-alkenylphenol-alkene-substrate-isolated-yield-ranking",
"doi": "10.1038/s41467-025-59405-x",
"title": "Cathodic oxygen reduction-enabled rhodium-catalyzed (5 + 1) C–H/O–H annulation inspired by fuel cells",
"authors": [
"Yuan-Qiong Huang",
"Li Zhu",
"Tian-Sheng Mei"
],
"journal": "Nature Communications",
"url": "https://www.nature.com/articles/s41467-025-59405-x"
},
{
"task_id": "copper-cyanoesterification-condition-conversion-ranking",
"doi": "10.1038/s41467-025-62137-7",
"title": "Asymmetric cyanoesterification of vinylarenes by electrochemical copper catalysis",
"authors": [
"Kehan Zhou",
"Niankai Fu"
],
"journal": "Nature Communications",
"url": "https://www.nature.com/articles/s41467-025-62137-7"
},
{
"task_id": "dabconium-oxidant-electrode-nmr-yield-ranking",
"doi": "10.1038/s44160-025-00890-9",
"title": "Electrochemical oxidation enables aromatic C–H amination with dual mechanisms",
"authors": [
"Griffin Stewart",
"Eva Maria Alvarez",
"Chris Rapala",
"Jonathan H. Sklar",
"Julia A. Kalow",
"Christian A. Malapit"
],
"journal": "Nature Synthesis",
"url": "https://www.nature.com/articles/s44160-025-00890-9"
},
{
"task_id": "ionic-cof-directional-solvent-permeance-ranking",
"doi": "10.1038/s41467-025-63240-5",
"title": "Asymmetric ionic covalent organic framework membranes with tunable Turing patterns prepared via ion regulated strategy",
"authors": [
"Jingcheng Du",
"Jian guan",
"Ali A. AL-Thuraya",
"Weiwang Lim",
"Qian Sun",
"Ayan Yao",
"Dong Cao",
"Ji Ma",
"Yuting zhang",
"Yumo Fan",
"Pengjia Dou",
"Jiangtao Liu"
],
"journal": "Nature Communications",
"url": "https://www.nature.com/articles/s41467-025-63240-5"
},
{
"task_id": "silver-ironoxyhydroxide-propylene-epoxidation-ranking",
"doi": "10.1038/s41467-025-67338-8",
"title": "In-situ spectroscopic insights into the dual-site synergistic electrocatalytic mechanism of propylene epoxidation over single-Ag-atom catalyst",
"authors": [
"Dengwen Pi",
"Xiaobo Yang",
"Meixin Chen",
"Jian Zhao",
"Jiuyi Wang",
"Shifu Wang",
"Wen-Cheng Shih",
"Wei Xu",
"Yanqiang Huang",
"Bin Liu",
"Xuning Li"
],
"journal": "Nature Communications",
"url": "https://www.nature.com/articles/s41467-025-67338-8"
},
{
"task_id": "palladium-bromoalkene-substrate-cyclization-isolated-yield-ranking",
"doi": "10.1038/s41467-025-58633-5",
"title": "Synthesis of benzoheterocycles by palladium-catalyzed migratory cyclization through an unexpected reaction cascade",
"authors": [
"Wen-Cong Li",
"Lin Zhang",
"Shiming Bai",
"Jia-Hao Zhao",
"Guang-Rui Liu",
"Yu Lan",
"Shufeng Chen",
"Jialin Ming"
],
"journal": "Nature Communications",
"url": "https://www.nature.com/articles/s41467-025-58633-5"
},
{
"task_id": "alkyl-iodide-nickel-difluoromethylation-additive-yield",
"doi": "10.1038/s41929-026-01505-y",
"title": "Enantioselective difluoromethylation of unactivated alkyl halides via a formal nickel(II/IV) cycle",
"authors": [
"Xian Zhao",
"Lingfeng Yin",
"Chia-Jung Yang",
"Andrew T. Poore",
"Xinyu Zhang",
"Stephen C. Yachuw",
"Chao Wang",
"Xiao Wang",
"Hairong Guan",
"Jeanette A. Krause",
"Mu-Jeng Cheng",
"Shiliang Tian",
"Wei Liu"
],
"journal": "Nature Catalysis",
"url": "https://www.nature.com/articles/s41929-026-01505-y"
},
{
"task_id": "alkyne-bridged-ester-palladium-screen",
"doi": "10.1038/s41467-025-64279-0",
"title": "Modular esterification of unstrained carbonyls through palladium-catalyzed alkyne bridging C-C bond activation",
"authors": [
"Mingruo Ding",
"Mengmeng Niu",
"Lingfei Hu",
"Qifan Guan",
"Shan Yuan",
"Yinghua Yu",
"Maojun Xiao",
"Shenlin Huang",
"Gang Lu",
"Xueliang Huang"
],
"journal": "Nature Communications",
"url": "https://www.nature.com/articles/s41467-025-64279-0"
},
{
"task_id": "bromovinyl-phosphine-migratory-cyclization-yield",
"doi": "10.1038/s41467-025-58633-5",
"title": "Synthesis of benzoheterocycles by palladium-catalyzed migratory cyclization through an unexpected reaction cascade",
"authors": [
"Wen-Cong Li",
"Lin Zhang",
"Shiming Bai",
"Jia-Hao Zhao",
"Guang-Rui Liu",
"Yu Lan",
"Shufeng Chen",
"Jialin Ming"
],
"journal": "Nature Communications",
"url": "https://www.nature.com/articles/s41467-025-58633-5"
},
{
"task_id": "pd-sulfoximine-solvent-cyclization-yield",
"doi": "10.1038/s41467-025-57251-5",
"title": "Asymmetric S=N-embedded polyaromatic construction via enantioselective Pd-catalyzed C–H activation",
"authors": [
"Daming Zeng",
"Xinyu Zhang",
"Ming Wang",
"Xuefeng Jiang"
],
"journal": "Nature Communications",
"url": "https://www.nature.com/articles/s41467-025-57251-5"
},
{
"task_id": "cobalt-vinyl-acetate-ligand-conversion",
"doi": "10.1038/s41467-025-62145-7",
"title": "A SaBOX/Co catalyst designed for facile access to the challenging copolymers of vinyl ester and methacrylate",
"authors": [
"Yi-Jie Ding",
"Sheng-Ye Zhang",
"Ya-Ning Li",
"Shu-Yang Yu",
"Kongchanghao Huang",
"Yuchen Zhang",
"Jun-Fang Li",
"Xiao-Yan Wang",
"Yong Tang"
],
"journal": "Nature Communications",
"url": "https://www.nature.com/articles/s41467-025-62145-7"
},
{
"task_id": "ethylene-ctfe-solvent-polymer-mass",
"doi": "10.1038/s41467-025-66962-8",
"title": "Photoredox-controlled alternating copolymerization enables highly crystalline structures and block copolymers from thermoplastic to elastomer",
"authors": [
"Mengli Xu",
"Qiankai Chen",
"Shantao Han",
"Kaixuan Chen",
"Xing Guo",
"Mao Chen"
],
"journal": "Nature Communications",
"url": "https://www.nature.com/articles/s41467-025-66962-8"
},
{
"task_id": "cobalt-methyl-methacrylate-catalyst-molar-mass-ranking",
"doi": "10.1038/s41467-025-62145-7",
"title": "A SaBOX/Co catalyst designed for facile access to the challenging copolymers of vinyl ester and methacrylate",
"authors": [
"Yi-Jie Ding",
"Sheng-Ye Zhang",
"Ya-Ning Li",
"Shu-Yang Yu",
"Kongchanghao Huang",
"Yuchen Zhang",
"Jun-Fang Li",
"Xiao-Yan Wang",
"Yong Tang"
],
"journal": "Nature Communications",
"url": "https://www.nature.com/articles/s41467-025-62145-7"
},
{
"task_id": "polymer-diels-alder-concentration-dose-yield-ranking",
"doi": "10.1038/s41467-025-65707-x",
"title": "Essential oil-derived decomposable polymers via cycloaddition polymerization of silyl ether-linked phenylpropanoids",
"authors": [
"Ryo Nagaya",
"Tatsuya Seko",
"Kazuhiro Okamoto",
"Kazuhide Ueno",
"Mahito Atobe",
"Naoki Shida"
],
"journal": "Nature Communications",
"url": "https://www.nature.com/articles/s41467-025-65707-x"
},
{
"task_id": "oxychloride-precursor-milling-conductivity-ranking",
"doi": "10.1038/s41467-025-68210-5",
"title": "Mechanically compliant and cost-effective 1.4Li2O-0.75ZrCl4-0.25AlCl3 solid electrolyte for all-solid-state batteries with improved cycling stability",
"authors": [
"Lv Hu",
"Yaolong He",
"Dong Wang",
"Wanxia Li",
"Jingming Yao",
"Xiaolong Zhang",
"Jinfeng Zhu",
"Huaican Chen",
"Wen Yin",
"Yanru Wang",
"Kejun Yan",
"Jinzhu Wang",
"Hui Li",
"Fang Chen",
"Yating Liu",
"Junqi Lai",
"Qi Chen",
"Jie Ma",
"Shuhong Jiao",
"Guorui Wang",
"Siqi Shi",
"Liwei Chen",
"Jianyu Huang",
"Cheng Ma"
],
"journal": "Nature Communications",
"url": "https://www.nature.com/articles/s41467-025-68210-5"
},
{
"task_id": "zinc-additive-eqcm-full-trace-response-ranking",
"doi": "10.1038/s41467-026-70366-7",
"title": "Electric-field-reinforced affinitive electrolytes for highly reversible aqueous zinc metal batteries",
"authors": [
"Ming Yang",
"Bao Zhang",
"An Duan",
"Sha Luo",
"Luyang Ge",
"Jiaqi Wang",
"Yuxi Zhang",
"Yu Feng",
"Xiao Huang",
"Yuyang Tang",
"Jia Yao",
"Hao Wang",
"Houzhao Wan",
"Wei Sun"
],
"journal": "Nature Communications",
"url": "https://www.nature.com/articles/s41467-026-70366-7"
},
{
"task_id": "zinc-electrolyte-organic-additive-contact-angle-ranking",
"doi": "10.1038/s41565-026-02187-0",
"title": "Hydrophobic liquid electrolyte interphases for efficient aqueous zinc batteries",
"authors": [
"Guanjie Li",
"Shilin Zhang",
"Jodie A. Yuwono",
"Xinyu Li",
"Javen Qinfeng Shi",
"Chunsheng Wang",
"Zaiping Guo"
],
"journal": "Nature Nanotechnology",
"url": "https://www.nature.com/articles/s41565-026-02187-0"
},
{
"task_id": "ether-zinc-electrolyte-concentration-lifespan-ranking",
"doi": "10.1038/s41565-026-02187-0",
"title": "Hydrophobic liquid electrolyte interphases for efficient aqueous zinc batteries",
"authors": [
"Guanjie Li",
"Shilin Zhang",
"Jodie A. Yuwono",
"Xinyu Li",
"Javen Qinfeng Shi",
"Chunsheng Wang",
"Zaiping Guo"
],
"journal": "Nature Nanotechnology",
"url": "https://www.nature.com/articles/s41565-026-02187-0"
},
{
"task_id": "metal-dicarboxylate-mof-first-capacity",
"doi": "10.1038/s41467-025-64711-5",
"title": "Low-strain metal–organic framework negative electrode for stable all-solid-state batteries",
"authors": [
"Minje Ryu",
"Sung-O Park",
"Seongje Lim",
"Hwasoo Lee",
"Jung Hwan Lee",
"Gwanghyun Lee",
"Ki Yoon Bae",
"Ji Young Kim",
"Youngsun Kong",
"Samick Son",
"Kisuk Kang",
"Jong Hyeok Park"
],
"journal": "Nature Communications",
"url": "https://www.nature.com/articles/s41467-025-64711-5"
},
{
"task_id": "metal-oxide-iridium-oxygen-evolution-current-ranking",
"doi": "10.1038/s41565-026-02136-x",
"title": "Proton–electron temporal asynchrony on femtosecond timescales enables anti-corrosive low-iridium anodes for PEM electrolysers",
"authors": [
"Wei Shen",
"Fei-Yue Gao",
"Xiaogang Sun",
"Haodian Xie",
"Yang Hu",
"Huiying Wu",
"Mietek Jaroniec",
"Yao Zheng",
"Pinxian Xi",
"Chun-Hua Yan",
"Shi-Zhang Qiao"
],
"journal": "Nature Nanotechnology",
"url": "https://www.nature.com/articles/s41565-026-02136-x"
},
{
"task_id": "silver-nickel-gasfed-electrolyte-co-efficiency-ranking",
"doi": "10.1038/s41467-025-65331-9",
"title": "Efficient amino-acid-based reactive capture of CO2 via nickel molecular catalyst",
"authors": [
"Zunmin Guo",
"Feng Li",
"Yurou Celine Xiao",
"Sung-Fu Hung",
"Ying-Rui Lu",
"Amir Foroozan",
"Jieyuan Liu",
"Siyu Sonia Sun",
"Shijie Liu",
"Yuxuan Che",
"Qiyou Wang",
"Min Liu",
"Cai Wang",
"Yuke Li",
"Kang-Shun Peng",
"Yu-Cheng Liu",
"Mengyang Fan",
"Zahra Azimi Dijvejin",
"Panagiotis Papangelakis",
"Yong Wang",
"Ali Shayesteh Zeraati",
"Kai Han",
"Paul Corbett",
"Drew Higgins",
"Rui Kai Miao",
"David Sinton"
],
"journal": "Nature Communications",
"url": "https://www.nature.com/articles/s41467-025-65331-9"
},
{
"task_id": "metal-zno-methane-product-ranking",
"doi": "10.1038/s41467-025-57854-y",
"title": "Photothermal direct methane conversion to formaldehyde at the gas-solid interface under ambient pressure",
"authors": [
"Yuxiong Wang",
"Yaoyu Zhang",
"Xiaoqiang Wang",
"Yue Liu",
"Zhongbiao Wu"
],
"journal": "Nature Communications",
"url": "https://www.nature.com/articles/s41467-025-57854-y"
},
{
"task_id": "mos2-znis-loading-hydrogen-180min",
"doi": "10.1038/s41467-025-66003-4",
"title": "Dipole synergy enables fast directional charge transport for solar hydrogen and benzaldehyde coproduction",
"authors": [
"Zhennan Wang",
"Dingyanyan Zhou",
"Kaige Tian",
"Guilin Chen",
"Youyong Li",
"Shengzhong Frank Liu",
"Shuit-Tong Lee",
"Yujin Ji",
"Junqing Yan"
],
"journal": "Nature Communications",
"url": "https://www.nature.com/articles/s41467-025-66003-4"
},
{
"task_id": "cuau-isotope-hydrogen-incorporation-ranking",
"doi": "10.1038/s41467-025-67317-z",
"title": "Catalyst alloying enables control over the electrochemical hydrogen transfer route",
"authors": [
"Jiguang Zhang",
"Chengyi Zhang",
"Weng Weei Tjiu",
"Tingting Fan",
"Yu-Chia Chang",
"Yu-Ting Chueh",
"Sibo Wang",
"Yan Zhang",
"Meng Wang",
"Qin Yang",
"Zeping Wang",
"Ruoou Yang",
"Zainul Aabdin",
"Sung-Fu Hung",
"Ziyun Wang",
"Yanwei Lum"
],
"journal": "Nature Communications",
"url": "https://www.nature.com/articles/s41467-025-67317-z"
},
{
"task_id": "perovskite-ligand-carrier-lifetime",
"doi": "10.1038/s41586-026-10626-0",
"title": "Stereoelectronic manipulation of ligands for perovskite solar cells",
"authors": [
"Tinghuan Yang",
"Erxin Zhao",
"Nan Wu",
"Xiaoming Chang",
"Chenqing Tian",
"Hai-Long Wang",
"Lu Zhang",
"Nannan Gu",
"Ting Nie",
"Ye Yang",
"Zheng Zhang",
"Tianfei Xu",
"Xin Chen",
"Shuang Wang",
"Tianqi Niu",
"Niansheng Xu",
"Chuang Ma",
"Haojin Li",
"Buyi Yan",
"Zicheng Ding",
"Shengzhong Frank Liu",
"Feng Gao",
"Kui Zhao"
],
"journal": "Nature",
"url": "https://www.nature.com/articles/s41586-026-10626-0"
},
{
"task_id": "hybrid-sam-coadsorbent-photovoltaic-ranking",
"doi": "10.1038/s41467-025-58111-y",
"title": "Modulating competitive adsorption of hybrid self-assembled molecules for efficient wide-bandgap perovskite solar cells and tandems",
"authors": [
"Chenyang Shi",
"Jianan Wang",
"Xia Lei",
"Qisen Zhou",
"Weitao Wang",
"Zhichun Yang",
"Sanwan Liu",
"Jiaqi Zhang",
"He Zhu",
"Rui Chen",
"Yongyan Pan",
"Zhengtian Tan",
"Wenguang Liu",
"Zhengjing Zhao",
"Zihe Cai",
"Xiaojun Qin",
"Zhiguo Zhao",
"Jingbai Li",
"Zonghao Liu",
"Wei Chen"
],
"journal": "Nature Communications",
"url": "https://www.nature.com/articles/s41467-025-58111-y"
},
{
"task_id": "amino-acid-peptide-nanotube-emission-band-ratio-ranking",
"doi": "10.1038/s44160-026-01054-z",
"title": "Handle-free attachment of small molecules on single-walled carbon nanotubes",
"authors": [
"Stanislav S. Piletsky",
"Erin E. Keblish",
"Alec R. Goffin",
"Xiaojia Jin",
"In-Jun Hwang",
"August Amb",
"Dmitri Kilin",
"Svetlana Kilina",
"Ming Zheng",
"Mijin Kim",
"Daniel A. Heller"
],
"journal": "Nature Synthesis",
"url": "https://www.nature.com/articles/s44160-026-01054-z"
},
{
"task_id": "pvdf-trfe-press-temperature-voltage",
"doi": "10.1038/s41467-025-67519-5",
"title": "Thermomechanical pressing and immediate quenching: enhanced piezoelectricity and transparency in piezoelectric nanofibers",
"authors": [
"Zhan Qu",
"Qian Chen",
"Xinyu Li",
"Jinyi Liu",
"Chenhong Lang",
"Yu Xu",
"Rujun Tang",
"Jizhen Zhang",
"Hongxia Wang",
"Yong Du",
"Tong Lin",
"Jian Fang"
],
"journal": "Nature Communications",
"url": "https://www.nature.com/articles/s41467-025-67519-5"
},
{
"task_id": "mownb-mica-compressive-temperature-response",
"doi": "10.1038/s41467-025-62100-6",
"title": "Highly customizable, ultrawide-temperature free-form flexible sensing electronic systems based on medium-entropy alloy paintings",
"authors": [
"Weiwei Li",
"Yingzhe Li",
"Manzhang Xu",
"Yilin Zhou",
"Ruoyan Miao",
"Kexin Wang",
"Yunqiang Cao",
"Yizhong Song",
"Siying Dang",
"Lu Zheng",
"Xuewen Wang",
"Wei Huang"
],
"journal": "Nature Communications",
"url": "https://www.nature.com/articles/s41467-025-62100-6"
},
{
"task_id": "metal-zif-nitrogen-adsorption-desorption-ranking",
"doi": "10.1038/s41467-025-62110-4",
"title": "Multivariate metal-organic frameworks enable chemical shift-encoded MRI with femtomolar sensitivity for biological systems",
"authors": [
"Qingbin Zeng",
"Quer Yue",
"Ming Zhang",
"Rui Zhou",
"Zhen Wang",
"Zhongyu Xiao",
"Yaping Yuan",
"Xiuchao Zhao",
"Weiping Jiang",
"Lei Zhang",
"Yuqi Yang",
"Minghui Yang",
"Haidong Li",
"Louis-S. Bouchard",
"Qianni Guo",
"Xin Zhou"
],
"journal": "Nature Communications",
"url": "https://www.nature.com/articles/s41467-025-62110-4"
},
{
"task_id": "oil-filter-air-transport-ranking",
"doi": "10.1038/s41586-025-09156-y",
"title": "Bioinspired capillary force-driven super-adhesive filter",
"authors": [
"Junyong Park",
"Chan Sik Moon",
"Ji Min Lee",
"Sazzadul A. Rahat",
"Sang Moon Kim",
"Jonathan T. Pham",
"Michael Kappl",
"Hans-Jürgen Butt",
"Sanghyuk Wooh"
],
"journal": "Nature",
"url": "https://www.nature.com/articles/s41586-025-09156-y"
},
{
"task_id": "pse-resin-ion-resistance-ranking",
"doi": "10.1038/s41467-025-58385-2",
"title": "Optimization and scaling-up of porous solid electrolyte electrochemical reactors for hydrogen peroxide electrosynthesis",
"authors": [
"Erzhuo Zhao",
"Yixin Zhang",
"Juhong Zhan",
"Guangsen Xia",
"Gang Yu",
"Yujue Wang"
],
"journal": "Nature Communications",
"url": "https://www.nature.com/articles/s41467-025-58385-2"
},
{
"task_id": "pva-cacl2-mineralization-mechanics",
"doi": "10.1038/s41467-025-66423-2",
"title": "Tough and tear resistant hydrogel with a sandwich mineralized structure induced by bidirectional ion migration",
"authors": [
"Dongsheng Yang",
"Zhiyu Zhao",
"Liangyu Zhu",
"Wenbin Tang",
"Zirou Qiu",
"Yifan Wu",
"Wenchuan Jiang",
"Cheng Lan",
"Yifu Zhang",
"Tao Liu",
"Heping Xie"
],
"journal": "Nature Communications",
"url": "https://www.nature.com/articles/s41467-025-66423-2"
},
{
"task_id": "hydrogel-additional-formulation-adhesion",
"doi": "10.1038/s41586-025-09269-4",
"title": "Data-driven de novo design of super-adhesive hydrogels",
"authors": [
"Hongguang Liao",
"Sheng Hu",
"Hu Yang",
"Lei Wang",
"Shinya Tanaka",
"Ichigaku Takigawa",
"Wei Li",
"Hailong Fan",
"Jian Ping Gong"
],
"journal": "Nature",
"url": "https://www.nature.com/articles/s41586-025-09269-4"
},
{
"task_id": "hydrogel-formulation-oscillatory-rheology",
"doi": "10.1038/s41586-025-09269-4",
"title": "Data-driven de novo design of super-adhesive hydrogels",
"authors": [
"Hongguang Liao",
"Sheng Hu",
"Hu Yang",
"Lei Wang",
"Shinya Tanaka",
"Ichigaku Takigawa",
"Wei Li",
"Hailong Fan",
"Jian Ping Gong"
],
"journal": "Nature",
"url": "https://www.nature.com/articles/s41586-025-09269-4"
},
{
"task_id": "tripeptide-dried-assembly-afm-modulus-ranking",
"doi": "10.1038/s41563-025-02300-z",
"title": "Adaptive peptide dispersions enable drying-induced biomolecule encapsulation",
"authors": [
"Dhwanit R. Dave",
"Salma Kassem",
"Maeva Coste",
"Lele Xu",
"Mona Tayarani-Najjaran",
"Darjan Podbevšek",
"Paola Colon-De Leon",
"Sheng Zhang",
"Luis Ortuno Macias",
"Deborah Sementa",
"María Pérez-Ferreiro",
"Nooshin Sadat Ayati",
"Muniyat A. Choudhury",
"Kelly Veerasammy",
"Selma Doganata",
"Tiffany Zhong",
"Cory Weng",
"Jorge Morales",
"Denize C. Favaro",
"Mateusz Marianski",
"So Yeon Ahn",
"Allie C. Obermeyer",
"Tong Wang",
"Tai-De Li",
"Xi Chen",
"Raymond Tu",
"Ye He",
"Rein V. Ulijn"
],
"journal": "Nature Materials",
"url": "https://www.nature.com/articles/s41563-025-02300-z"
},
{
"task_id": "twisted-plywood-matrix-angle-fracture-ranking",
"doi": "10.1038/s41467-024-55723-8",
"title": "Distorting crack-front geometry for enhanced toughness by manipulating bioinspired heterogeneity",
"authors": [
"Kaijin Wu",
"Zhaoqiang Song",
"Mengqi Liu",
"Zewen Wang",
"Si-Ming Chen",
"Shu-Hong Yu",
"Linghui He",
"Yong Ni"
],
"journal": "Nature Communications",
"url": "https://www.nature.com/articles/s41467-024-55723-8"
},
{
"task_id": "lipoic-acid-dbu-molar-ratio-adhesion-ranking",
"doi": "10.1038/s41467-025-62917-1",
"title": "Reversible biobased adhesives enable closed-loop engineered composites",
"authors": [
"Jin Lv",
"Daxin Zhang",
"Xinkai Li",
"Yinggang Miao",
"Yuyan Wang",
"Ying Wang",
"Xinxing Zhang"
],
"journal": "Nature Communications",
"url": "https://www.nature.com/articles/s41467-025-62917-1"
},
{
"task_id": "underwater-adhesive-prototype-configuration-ranking",
"doi": "10.1038/s41586-025-09304-4",
"title": "Mechanical underwater adhesive devices for soft substrates",
"authors": [
"Ziliang Kang",
"Johanna A. Gomez",
"Alisa MeiShan Ross",
"Ameya R. Kirtane",
"Ming Zhao",
"Yubin Cai",
"Fu Xing Chen",
"Corona L. Chen",
"Isaac Diaz Becdach",
"Rajib Dey",
"Andrei Russel Ismael",
"Injoo Moon",
"Yiyuan Yang",
"Benjamin N. Muller",
"Mehmet Girayhan Say",
"Andrew Pettinari",
"Jason Kobrin",
"Joshua Morimoto",
"Ted Smierciak",
"Aaron Lopes",
"Ayten Ebru Erdogan",
"Matt Murphy",
"Niora Fabian",
"Ashley Guevara",
"Benedict Laidlaw",
"Kailyn Schmidt",
"Alison M. Hayward",
"Alexandra H. Techet",
"Christopher P. Kenaley",
"Giovanni Traverso"
],
"journal": "Nature",
"url": "https://www.nature.com/articles/s41586-025-09304-4"
},
{
"task_id": "agcute-bending-endpoints-ranking",
"doi": "10.1038/s41467-025-58104-x",
"title": "Strategic vacancy engineering advances record-high ductile AgCu(Te, Se, S) thermoelectrics",
"authors": [
"Nan-Hai Li",
"Xiao-Lei Shi",
"Si-Qi Liu",
"Meng Li",
"Tian-Yi Cao",
"Min Zhang",
"Wan-Yu Lyu",
"Wei-Di Liu",
"Dong-Chen Qi",
"Zhi-Gang Chen"
],
"journal": "Nature Communications",
"url": "https://www.nature.com/articles/s41467-025-58104-x"
},
{
"task_id": "fenicoalta-processing-tensile-properties",
"doi": "10.1038/s41586-025-09160-2",
"title": "Machine-learning design of ductile FeNiCoAlTa alloys with high strength",
"authors": [
"Yasir Sohail",
"Chongle Zhang",
"Dezhen Xue",
"Jinyu Zhang",
"Dongdong Zhang",
"Shaohua Gao",
"Yang Yang",
"Xiaoxuan Fan",
"Hang Zhang",
"Gang Liu",
"Jun Sun",
"En Ma"
],
"journal": "Nature",
"url": "https://www.nature.com/articles/s41586-025-09160-2"
},
{
"task_id": "fenicoalta-tensile-compositions",
"doi": "10.1038/s41586-025-09160-2",
"title": "Machine-learning design of ductile FeNiCoAlTa alloys with high strength",
"authors": [
"Yasir Sohail",
"Chongle Zhang",
"Dezhen Xue",
"Jinyu Zhang",
"Dongdong Zhang",
"Shaohua Gao",
"Yang Yang",
"Xiaoxuan Fan",
"Hang Zhang",
"Gang Liu",
"Jun Sun",
"En Ma"
],
"journal": "Nature",
"url": "https://www.nature.com/articles/s41586-025-09160-2"
},
{
"task_id": "empty-lipid-nanoparticle-zeta-potential-ranking",
"doi": "10.1038/s41565-025-01958-5",
"title": "Tailoring the adjuvanticity of lipid nanoparticles by PEG lipid ratio and phospholipid modifications",
"authors": [
"Máté Vadovics",
"Wenchen Zhao",
"Emily F. Daley",
"Kieu Lam",
"Owen Daly",
"Khalid Rashid",
"Hailey R. Lee",
"Petra Schreiner",
"Kendall A. Lundgreen",
"Brian T. Gaudette",
"Vladimir V. Shuvaev",
"Evguenia Arguiri",
"Hiromi Muramatsu",
"András Sárközy",
"Thandiswa Mdluli",
"Junchao Xu",
"Xuexiang Han",
"Nina De Luna",
"Diana Castaño",
"Emily Bettini",
"Edit Ábrahám",
"Zoltan Lipinszki",
"Giuseppe Carlucci",
"Avinash Haridas Bansode",
"Katelyn Nguyen",
"Thuc M. Le",
"Tony Luu",
"Vladimir R. Muzykantov",
"Paul Bates",
"David Allman",
"Michael J. Mitchell",
"Michela Locci",
"Caius G. Radu",
"James Heyes",
"Norbert Pardi"
],
"journal": "Nature Nanotechnology",
"url": "https://www.nature.com/articles/s41565-025-01958-5"
},
{
"task_id": "gastruloid-signalling-cell-count-ranking",
"doi": "10.1038/s41556-026-01923-x",
"title": "Mosaic gastruloids reveal a temporal restriction for developmental cell competition",
"authors": [
"Joshua D. Frenster",
"Stephen Babin",
"Pablo Casani-Galdon",
"Joel B. Josende-Garcia",
"Pau Pascual-Mas",
"Gaëlle Robertson",
"Shlomit Edri",
"Alexandra E. Wehmeyer",
"Sebastian J. Arnold",
"Jordi Garcia Ojalvo",
"Alfonso Martinez Arias"
],
"journal": "Nature Cell Biology",
"url": "https://www.nature.com/articles/s41556-026-01923-x"
},
{
"task_id": "fmn-aptamer-fluorescence-ranking",
"doi": "10.1038/s41467-025-60722-4",
"title": "Rational development of FMN-based orthogonal riboswitch that functions in response to specific non-cognate ligand",
"authors": [
"Divya Ojha",
"Ambadas B. Rode"
],
"journal": "Nature Communications",
"url": "https://www.nature.com/articles/s41467-025-60722-4"
},
{
"task_id": "bik1-positional-peptide-library-phosphorylation-ranking",
"doi": "10.1038/s41477-025-02218-z",
"title": "Motif-based substrate mapping of the receptor-like cytoplasmic kinase BIK1 reveals novel components and regulatory nodes of plant immunity",
"authors": [
"Ryan Toth",
"Sera Choi",
"Marie Le Naour--Vernet",
"Florian Schwanke",
"Jared L. Johnson",
"Estee E. Tee",
"Tomer M. Yaron-Barir",
"Eleanor Khochaba",
"Paul Derbyshire",
"Anka Colo",
"Philipp Köster",
"Emily M. Huntsman",
"Laura Herold",
"Yoonyoung Lee",
"Álvaro D. Fernández-Fernández",
"Hee-Kyung Ahn",
"Julian Dindas",
"Marta Bjornson",
"Jack Rhodes",
"Beibei Song",
"Weibing Wang",
"Marija Smokvarska",
"Emmanuelle M. Bayer",
"Jian-Min Zhou",
"Lewis C. Cantley",
"Jonathan D. G. Jones",
"Kyle W. Bender",
"Frank L. H. Menke",
"Christine Faulkner",
"Cyril Zipfel",
"Thomas A. DeFalco"
],
"journal": "Nature Plants",
"url": "https://www.nature.com/articles/s41477-025-02218-z"
},
{
"task_id": "tomato-multilocus-field-branching",
"doi": "10.1038/s41586-025-09243-0",
"title": "Cryptic variation fuels plant phenotypic change through hierarchical epistasis",
"authors": [
"Sophia G. Zebell",
"Carlos Martí-Gómez",
"Blaine Fitzgerald",
"Camila P. Cunha",
"Michael Lach",
"Brooke M. Seman",
"Anat Hendelman",
"Simon Sretenovic",
"Yiping Qi",
"Madelaine Bartlett",
"Yuval Eshed",
"David M. McCandlish",
"Zachary B. Lippman"
],
"journal": "Nature",
"url": "https://www.nature.com/articles/s41586-025-09243-0"
},
{
"task_id": "arabidopsis-centromere-recombination-ranking",
"doi": "10.1038/s41477-026-02329-1",
"title": "The deSUMOylase SPF2 and the cohesin regulators SGO2 and CTF18 suppress crossovers near centromeres",
"authors": [
"Rigel Salinas Gamboa",
"Joiselle Blanche Fernandes",
"Qichao Lian",
"Dipesh Kumar Singh",
"Stephanie Durand",
"Divyanshu Sahu",
"Laia Capilla-Perez",
"Hernan Lopez",
"Alexandra Kalde",
"Raphael Mercier"
],
"journal": "Nature Plants",
"url": "https://www.nature.com/articles/s41477-026-02329-1"
},
{
"task_id": "arabidopsis-amino-acid-dark-chlorophyll-ranking",
"doi": "10.1038/s41477-026-02328-2",
"title": "The progression of leaf senescence is gated by the cytosolic arginine pool",
"authors": [
"Shah Hussain",
"Clément Boussardon",
"Olivier Keech"
],
"journal": "Nature Plants",
"url": "https://www.nature.com/articles/s41477-026-02328-2"
},
{
"task_id": "sgc-mitochondrial-transfer-ranking",
"doi": "10.1038/s41586-025-09896-x",
"title": "Mitochondrial transfer from glia to neurons protects against peripheral neuropathy",
"authors": [
"Jing Xu",
"Yize Li",
"Charles Novak",
"Min Lee",
"Zihan Yan",
"Sangsu Bang",
"Aidan McGinnis",
"Sharat Chandra",
"Vivian Zhang",
"Wei He",
"Terry Lechler",
"Maria Pia Rodriguez Salazar",
"Cagla Eroglu",
"Matthew L. Becker",
"Dmitry Velmeshev",
"Richard E. Cheney",
"Ru-Rong Ji"
],
"journal": "Nature",
"url": "https://www.nature.com/articles/s41586-025-09896-x"
},
{
"task_id": "peptide-fos-expression-ranking",
"doi": "10.1038/s41586-025-08683-y",
"title": "Prohormone cleavage prediction uncovers a non-incretin anti-obesity peptide",
"authors": [
"Laetitia Coassolo",
"Niels B. Danneskiold-Samsøe",
"Quennie Nguyen",
"Amanda Wiggenhorn",
"Meng Zhao",
"David Cheng-Hao Wang",
"David Toomer",
"Jameel Lone",
"Yichao Wei",
"Aayan Patel",
"Irene Liparulo",
"Deniz Kavi",
"Lianna W. Wat",
"Saranya Chidambaranathan Reghupaty",
"Julie Jae Kim",
"Tina Asemi",
"Ewa Bielczyk-Maczynska",
"Veronica L. Li",
"Maria Dolores Moya-Garzon",
"Nicole A. J. Krentz",
"Andreas Stahl",
"Danny Hung-Chieh Chou",
"Liqun Luo",
"Katrin J. Svensson"
],
"journal": "Nature",
"url": "https://www.nature.com/articles/s41586-025-08683-y"
},
{
"task_id": "sgc-neuronal-nanotube-incidence",
"doi": "10.1038/s41586-025-09896-x",
"title": "Mitochondrial transfer from glia to neurons protects against peripheral neuropathy",
"authors": [
"Jing Xu",
"Yize Li",
"Charles Novak",
"Min Lee",
"Zihan Yan",
"Sangsu Bang",
"Aidan McGinnis",
"Sharat Chandra",
"Vivian Zhang",
"Wei He",
"Terry Lechler",
"Maria Pia Rodriguez Salazar",
"Cagla Eroglu",
"Matthew L. Becker",
"Dmitry Velmeshev",
"Richard E. Cheney",
"Ru-Rong Ji"
],
"journal": "Nature",
"url": "https://www.nature.com/articles/s41586-025-09896-x"
},
{
"task_id": "cell-state-ump-isotope-tracing-ranking",
"doi": "10.1038/s42255-026-01520-0",
"title": "Nitrogen metabolism profiling reveals cell state-specific pyrimidine synthesis pathway choice",
"authors": [
"Milan R. Savani",
"Bingbing Li",
"Bailey C. Smith",
"Wen Gu",
"Yi Xiao",
"Gerard Baquer",
"Tracey Shipman",
"Skyler S. Oken",
"Namya Manoj",
"Lauren G. Zacharias",
"Vinesh T. Puliyappadamba",
"Sylwia A. Stopka",
"Michael S. Regan",
"Michael M. Levitt",
"Charles K. Edgar",
"William H. Hicks",
"Soummitra Anand",
"Misty S. Martin-Sandoval",
"Rainah Winston",
"João S. Patrício",
"Xandria Johnson",
"Trevor S. Tippetts",
"Diana D. Shi",
"Andrew Lemoff",
"Timothy E. Richardson",
"Pascal O. Zinn",
"Ashley Solmonson",
"Thomas P. Mathews",
"Nathalie Y. R. Agar",
"Ralph J. DeBerardinis",
"Kalil G. Abdullah",
"Samuel K. McBrayer"
],
"journal": "Nature Metabolism",
"url": "https://www.nature.com/articles/s42255-026-01520-0"
},
{
"task_id": "cancer-cell-ttfa-viability-ranking",
"doi": "10.1038/s42255-025-01410-x",
"title": "Pathway coessentiality mapping reveals complex II is required for de novo purine biosynthesis in acute myeloid leukaemia",
"authors": [
"Amy E. Stewart",
"Derek K. Zachman",
"Pol Castellano-Escuder",
"Lois M. Kelly",
"Ben Zolyomi",
"Michael D. I. Aiduk",
"Christopher D. Delaney",
"Ian C. Lock",
"Claudie Bosc",
"John Bradley",
"Shane T. Killarney",
"J. Darren Stuart",
"Paul A. Grimsrud",
"Olga R. Ilkayeva",
"Christopher B. Newgard",
"Navdeep S. Chandel",
"Alexandre Puissant",
"Kris C. Wood",
"Matthew D. Hirschey"
],
"journal": "Nature Metabolism",
"url": "https://www.nature.com/articles/s42255-025-01410-x"
},
{
"task_id": "dna-polyploidization-route-fractions",
"doi": "10.1038/s41586-025-08986-0",
"title": "Multigenerational cell tracking of DNA replication and heritable DNA damage",
"authors": [
"Andreas Panagopoulos",
"Merula Stout",
"Sinan Kilic",
"Peter Leary",
"Julia Vornberger",
"Virginia Pasti",
"Antonio Galarreta",
"Aleksandra Lezaja",
"Kyra Kirschenbühler",
"Ralph Imhof",
"Hubert Rehrauer",
"Urs Ziegler",
"Matthias Altmeyer"
],
"journal": "Nature",
"url": "https://www.nature.com/articles/s41586-025-08986-0"
},
{
"task_id": "ministeria-transcription-transcript-timecourse",
"doi": "10.1038/s41586-026-10748-5",
"title": "A unicellular relative links aggregative multicellularity to animal origins",
"authors": [
"Ruibao Li",
"Jennah E. Dharamshi",
"Kyle Kwok",
"Iñaki Ruiz-Trillo",
"Joseph P. Gerdt"
],
"journal": "Nature",
"url": "https://www.nature.com/articles/s41586-026-10748-5"
},
{
"task_id": "ministeria-phagocytosis-transcript-timecourse",
"doi": "10.1038/s41586-026-10748-5",
"title": "A unicellular relative links aggregative multicellularity to animal origins",
"authors": [
"Ruibao Li",
"Jennah E. Dharamshi",
"Kyle Kwok",
"Iñaki Ruiz-Trillo",
"Joseph P. Gerdt"
],
"journal": "Nature",
"url": "https://www.nature.com/articles/s41586-026-10748-5"
},
{
"task_id": "syoa-substrate-binding-ranking",
"doi": "10.1038/s41467-025-57129-6",
"title": "Structural insights into S-lignin O-demethylation via a rare class of heme peroxygenase enzymes",
"authors": [
"Alix C. Harlington",
"Tuhin Das",
"Keith E. Shearwin",
"Stephen G. Bell",
"Fiona Whelan"
],
"journal": "Nature Communications",
"url": "https://www.nature.com/articles/s41467-025-57129-6"
},
{
"task_id": "kemp-sequence-ranking",
"doi": "10.1038/s41586-025-09136-2",
"title": "Complete computational design of high-efficiency Kemp elimination enzymes",
"authors": [
"Dina Listov",
"Eva Vos",
"Gyula Hoffka",
"Shlomo Yakir Hoch",
"Andrej Berg",
"Shelly Hamer-Rogotner",
"Orly Dym",
"Shina Caroline Lynn Kamerlin",
"Sarel J. Fleishman"
],
"journal": "Nature",
"url": "https://www.nature.com/articles/s41586-025-09136-2"
},
{
"task_id": "kemp-sequence-thermal-stability",
"doi": "10.1038/s41586-025-09136-2",
"title": "Complete computational design of high-efficiency Kemp elimination enzymes",
"authors": [
"Dina Listov",
"Eva Vos",
"Gyula Hoffka",
"Shlomo Yakir Hoch",
"Andrej Berg",
"Shelly Hamer-Rogotner",
"Orly Dym",
"Shina Caroline Lynn Kamerlin",
"Sarel J. Fleishman"
],
"journal": "Nature",
"url": "https://www.nature.com/articles/s41586-025-09136-2"
},
{
"task_id": "p450bm3-quinoline-conversion-selectivity-ranking",
"doi": "10.1038/s41467-025-61773-3",
"title": "Regulating the N-oxidation selectivity of P450BM3 monooxygenases for N-heterocycles through computer-assisted structure-guided design",
"authors": [
"Liu Yang",
"Zhongji Pu",
"Jianping Wu",
"Xiaofeng Liu",
"Zhe Wang",
"Haoran Yu",
"Liuwei Wang",
"Yan Meng",
"Gang Xu",
"Lirong Yang",
"Wenlong Zheng"
],
"journal": "Nature Communications",
"url": "https://www.nature.com/articles/s41467-025-61773-3"
},
{
"task_id": "pes-h1-activity-thermal-ranking",
"doi": "10.1038/s41467-025-55944-5",
"title": "Tailoring industrial enzymes for thermostability and activity evolution by the machine learning-based iCASE strategy",
"authors": [
"Nan Zheng",
"Yongchao Cai",
"Zehua Zhang",
"Huimin Zhou",
"Yu Deng",
"Shuang Du",
"Mai Tu",
"Wei Fang",
"Xiaole Xia"
],
"journal": "Nature Communications",
"url": "https://www.nature.com/articles/s41467-025-55944-5"
},
{
"task_id": "mcba-cellfree-amidation-ranking",
"doi": "10.1038/s41467-024-55399-0",
"title": "Accelerated enzyme engineering by machine-learning guided cell-free expression",
"authors": [
"Grant M. Landwehr",
"Jonathan W. Bogart",
"Carol Magalhaes",
"Eric G. Hammarlund",
"Ashty S. Karim",
"Michael C. Jewett"
],
"journal": "Nature Communications",
"url": "https://www.nature.com/articles/s41467-024-55399-0"
},
{
"task_id": "diet-baseline-leukocyte-ranking",
"doi": "10.1038/s41586-026-10750-x",
"title": "Diet–microbiome synergy underlies obesity-associated immunotherapy efficacy",
"authors": [
"Lysanne Desharnais",
"Anikka Swaby",
"Meriem Messaoudene",
"Samuel Doré",
"Miranda W. Yu",
"Benoit Fiset",
"Valérie Breton",
"Mayra Ponce",
"Yongjia Hu",
"Liam Wilson",
"Mark Sorin",
"Ye Wang",
"Ken Dewar",
"Michael Pollak",
"Arielle Elkrief",
"Bertrand Routy",
"Logan A. Walsh",
"Daniela F. Quail"
],
"journal": "Nature",
"url": "https://www.nature.com/articles/s41586-026-10750-x"
},
{
"task_id": "cortical-neuron-compound-dose-outgrowth",
"doi": "10.1038/s41586-025-09647-y",
"title": "Thiorphan reprograms neurons to promote functional recovery after spinal cord injury",
"authors": [
"E. A. van Niekerk",
"C. Marques de Freria",
"B. O. Mancarci",
"K. Groeniger",
"D. Kulinich",
"T. Riley",
"R. Kawaguchi",
"S. Okawa",
"T. Vokes",
"E. S. Rosenzweig",
"E. Sinopoulou",
"M. J. Castle",
"R. Huie",
"A. R. Ferguson",
"N. Kfoury-Beaumont",
"A. Khalessi",
"P. Pavlidis",
"M. H. Tuszynski"
],
"journal": "Nature",
"url": "https://www.nature.com/articles/s41586-025-09647-y"
},
{
"task_id": "erbb4-deletion-brain-histology",
"doi": "10.1038/s41586-026-10964-z",
"title": "Aberrant excitatory neuronal ERBB4 promotes Alzheimer’s disease pathology",
"authors": [
"Se Young Lee",
"Eunseok Park",
"Ha-Eun Lee",
"Seongbin Kim",
"Yeji Yeo",
"Juwon Park",
"Young-Jin Choi",
"Kiheon Lee",
"Ki-Jun Yoon",
"Sanghoon Park",
"Eunjoon Kim",
"Jae-Ick Kim",
"Won-Suk Chung"
],
"journal": "Nature",
"url": "https://www.nature.com/articles/s41586-026-10964-z"
},
{
"task_id": "brp-sequence-acute-food-intake",
"doi": "10.1038/s41586-025-08683-y",
"title": "Prohormone cleavage prediction uncovers a non-incretin anti-obesity peptide",
"authors": [
"Laetitia Coassolo",
"Niels B. Danneskiold-Samsøe",
"Quennie Nguyen",
"Amanda Wiggenhorn",
"Meng Zhao",
"David Cheng-Hao Wang",
"David Toomer",
"Jameel Lone",
"Yichao Wei",
"Aayan Patel",
"Irene Liparulo",
"Deniz Kavi",
"Lianna W. Wat",
"Saranya Chidambaranathan Reghupaty",
"Julie Jae Kim",
"Tina Asemi",
"Ewa Bielczyk-Maczynska",
"Veronica L. Li",
"Maria Dolores Moya-Garzon",
"Nicole A. J. Krentz",
"Andreas Stahl",
"Danny Hung-Chieh Chou",
"Liqun Luo",
"Katrin J. Svensson"
],
"journal": "Nature",
"url": "https://www.nature.com/articles/s41586-025-08683-y"
},
{
"task_id": "picalm-lipid-class-abundance",
"doi": "10.1038/s41586-025-09486-x",
"title": "PICALM Alzheimer’s risk allele causes aberrant lipid droplets in microglia",
"authors": [
"Alena Kozlova",
"Siwei Zhang",
"Ari Sudwarts",
"Hanwen Zhang",
"Stanislau Smirnou",
"Seul Kee Byeon",
"Christina Thapa",
"Xiaotong Sun",
"Kimberley Stephenson",
"Xiaojie Zhao",
"Brendan Jamison",
"Moorthi Ponnusamy",
"Xin He",
"Julie A. Schneider",
"Akhilesh Pandey",
"David A. Bennett",
"Zhiping P. Pang",
"Alan R. Sanders",
"Hugo J. Bellen",
"Gopal Thinakaran",
"Jubao Duan"
],
"journal": "Nature",
"url": "https://www.nature.com/articles/s41586-025-09486-x"
},
{
"task_id": "pancreatic-kras-lipogenic-transcripts",
"doi": "10.1038/s41586-025-08917-z",
"title": "Targeting PIKfyve-driven lipid metabolism in pancreatic cancer",
"authors": [
"Caleb Cheng",
"Jing Hu",
"Rahul Mannan",
"Tongchen He",
"Rupam Bhattacharyya",
"Brian Magnuson",
"Jasmine P. Wisniewski",
"Sydney Peters",
"Saadia A. Karim",
"David J. MacLean",
"Hüseyin Karabürk",
"Li Zhang",
"Nicholas J. Rossiter",
"Yang Zheng",
"Lanbo Xiao",
"Chungen Li",
"Dominik Awad",
"Somnath Mahapatra",
"Yi Bao",
"Yuping Zhang",
"Xuhong Cao",
"Zhen Wang",
"Rohit Mehra",
"Pietro Morlacchi",
"Vaibhav Sahai",
"Marina Pasca di Magliano",
"Yatrik M. Shah",
"Lois S. Weisman",
"Jennifer P. Morton",
"Ke Ding",
"Yuanyuan Qiao",
"Costas A. Lyssiotis",
"Arul M. Chinnaiyan"
],
"journal": "Nature",
"url": "https://www.nature.com/articles/s41586-025-08917-z"
},
{
"task_id": "human-tumour-oxidized-lipid-response",
"doi": "10.1038/s41586-025-08974-4",
"title": "Activation of lysosomal iron triggers ferroptosis in cancer",
"authors": [
"Tatiana Cañeque",
"Leeroy Baron",
"Sebastian Müller",
"Alanis Carmona",
"Ludovic Colombeau",
"Antoine Versini",
"Stéphanie Solier",
"Christine Gaillet",
"Fabien Sindikubwabo",
"Julio L. Sampaio",
"Marie Sabatier",
"Eikan Mishima",
"Armel Picard-Bernes",
"Laurène Syx",
"Nicolas Servant",
"Bérangère Lombard",
"Damarys Loew",
"Jiashuo Zheng",
"Bettina Proneth",
"Leishemba K. Thoidingjam",
"Laurence Grimaud",
"Cameron S. Fraser",
"Krystina J. Szylo",
"Emma Der Kazarian",
"Caroline Bonnet",
"Emmanuelle Charafe-Jauffret",
"Christophe Ginestier",
"Patricia Santofimia-Castaño",
"Matias Estaras",
"Nelson Dusetti",
"Juan Lucio Iovanna",
"Antonio Sa Cunha",
"Gabriella Pittau",
"Pascal Hammel",
"Dimitri Tzanis",
"Sylvie Bonvalot",
"Sarah Watson",
"Vincent Gandon",
"Aditya Upadhyay",
"Derek A. Pratt",
"Florêncio Porto Freitas",
"José Pedro Friedmann Angeli",
"Brent R. Stockwell",
"Marcus Conrad",
"Jessalyn M. Ubellacker",
"Raphaël Rodriguez"
],
"journal": "Nature",
"url": "https://www.nature.com/articles/s41586-025-08974-4"
},
{
"task_id": "cancer-cell-atra-ic50-ranking",
"doi": "10.1038/s41467-025-57185-y",
"title": "Bone morphogenetic protein (BMP) signaling determines neuroblastoma cell fate and sensitivity to retinoic acid",
"authors": [
"Min Pan",
"Yinwen Zhang",
"William C. Wright",
"Xueying Liu",
"Barbara Passaia",
"Duane Currier",
"Jonathan Low",
"Richard H. Chapple",
"Jacob A. Steele",
"Jon P. Connelly",
"Bensheng Ju",
"Emily Plyler",
"Meifen Lu",
"Allister J. Loughran",
"Lei Yang",
"Brian J. Abraham",
"Shondra M. Pruett-Miller",
"Burgess Freeman",
"George E. Campbell",
"Michael A. Dyer",
"Taosheng Chen",
"Elizabeth Stewart",
"Selene Koo",
"Heather Sheppard",
"John Easton",
"Paul Geeleher"
],
"journal": "Nature Communications",
"url": "https://www.nature.com/articles/s41467-025-57185-y"
},
{
"task_id": "pooled-cell-drug-representation-ranking",
"doi": "10.1038/s43018-026-01130-5",
"title": "The GENEVA platform models tumor mosaicism to reveal variations of responses to KRAS inhibitors and identify improved drug combinations",
"authors": [
"Johnny X. Yu",
"Jung Min Suh",
"Katerina D. Popova",
"Kristle Garcia",
"Tanvi Joshi",
"Bruce Culbertson",
"Jessica B. Spinelli",
"Vishvak Subramanyam",
"Kevin Lou",
"Trey Charbonneau",
"Kevan M. Shokat",
"Jonathan Weissman",
"Hani Goodarzi"
],
"journal": "Nature Cancer",
"url": "https://www.nature.com/articles/s43018-026-01130-5"
},
{
"task_id": "grpr-yap1-nuclear-localization",
"doi": "10.1038/s41586-025-09111-x",
"title": "Targeting GRPR for sex hormone-dependent cancer after loss of E-cadherin",
"authors": [
"Jérémy H. Raymond",
"Zackie Aktary",
"Marie Pouteaux",
"Valérie Petit",
"Flavie Luciani",
"Maria Wehbe",
"Patrick Gizzi",
"Claire Bourban",
"Didier Decaudin",
"Fariba Nemati",
"Igor Martianov",
"Irwin Davidson",
"Catherine-Laure Tomasetto",
"Richard M. White",
"Florence Mahuteau-Betzer",
"Béatrice Vergier",
"Lionel Larue",
"Véronique Delmas"
],
"journal": "Nature",
"url": "https://www.nature.com/articles/s41586-025-09111-x"
},
{
"task_id": "grpr-melanoma-matrigel-invasion",
"doi": "10.1038/s41586-025-09111-x",
"title": "Targeting GRPR for sex hormone-dependent cancer after loss of E-cadherin",
"authors": [
"Jérémy H. Raymond",
"Zackie Aktary",
"Marie Pouteaux",
"Valérie Petit",
"Flavie Luciani",
"Maria Wehbe",
"Patrick Gizzi",
"Claire Bourban",
"Didier Decaudin",
"Fariba Nemati",
"Igor Martianov",
"Irwin Davidson",
"Catherine-Laure Tomasetto",
"Richard M. White",
"Florence Mahuteau-Betzer",
"Béatrice Vergier",
"Lionel Larue",
"Véronique Delmas"
],
"journal": "Nature",
"url": "https://www.nature.com/articles/s41586-025-09111-x"
},
{
"task_id": "ly2090314-cell-growth-inhibition-ranking",
"doi": "10.1038/s43018-025-01093-z",
"title": "Targeting β-catenin degradation with GSK3β inhibitors induces cell death in acute lymphoblastic leukemia",
"authors": [
"Kadriye Nehir Cosgun",
"Huda Jumaa",
"Mark E. Robinson",
"Zhangliang Cheng",
"Salim Oulghazi",
"Kohei Kume",
"David Fonseca Arce",
"Nikol Agadzhanian",
"Klaus M. Kistner",
"Etienne Leveille",
"Elsa Drivet",
"Fang Yu",
"Zhijian Qian",
"Joo Y. Song",
"Wing-Chung Chan",
"Liang Xu",
"Gang Xiao",
"M. Mark Taketo",
"Shalin Kothari",
"Matthew S. Davids",
"Hilde Schjerven",
"Julia Jellusova",
"Markus Müschen"
],
"journal": "Nature Cancer",
"url": "https://www.nature.com/articles/s43018-025-01093-z"
}
]
}
{
"tasks": [
{
"task_id": "amine-borane-arylation-bases",
"doi": "10.1038/s41586-025-09725-1",
"title": "Deaminative cross-coupling of amines by boryl radical β-scission",
"authors": [
"Zhenhua Zhang",
"Giovanni Lonardi",
"Thomas Sephton",
"Yusuf C. Guersoy",
"Chiara Stavagna",
"Giovanni V. A. Lenardon",
"Massimo Bietti",
"Daniele Leonori"
],
"journal": "Nature",
"url": "https://www.nature.com/articles/s41586-025-09725-1"
},
{
"task_id": "amine-borane-divergent-functionalization-ranking",
"doi": "10.1038/s41586-025-09725-1",
"title": "Deaminative cross-coupling of amines by boryl radical β-scission",
"authors": [
"Zhenhua Zhang",
"Giovanni Lonardi",
"Thomas Sephton",
"Yusuf C. Guersoy",
"Chiara Stavagna",
"Giovanni V. A. Lenardon",
"Massimo Bietti",
"Daniele Leonori"
],
"journal": "Nature",
"url": "https://www.nature.com/articles/s41586-025-09725-1"
},
{
"task_id": "bora-butenolide-conjugated-substrates",
"doi": "10.1038/s41467-025-60052-5",
"title": "Expedient access to bora-butenolide bioisosteres by counteranion-mediated trans-hydroboration of alkynes",
"authors": [
"Yuan-Wen Liu",
"Yu Liu",
"Yanting Zheng",
"Mengfan Zhang",
"Meng-En Ren",
"Peiyu Hua",
"Jie Han",
"Alois Fürstner",
"Hongming Jin"
],
"journal": "Nature Communications",
"url": "https://www.nature.com/articles/s41467-025-60052-5"
},
{
"task_id": "dialuminum-quinoline-catalyst-loading-yield",
"doi": "10.1038/s41467-025-63460-9",
"title": "Regio- and chemoselective catalytic partial transfer hydrogenation of quinolines by dinuclear aluminum species",
"authors": [
"Xufang Liu",
"Arseni Kostenko",
"Matthew M. D. Roy",
"Tobias Weng",
"Shigeyoshi Inoue"
],
"journal": "Nature Communications",
"url": "https://www.nature.com/articles/s41467-025-63460-9"
},
{
"task_id": "benzothiophene-photodimer-solvent-yield",
"doi": "10.1038/s41467-026-75078-6",
"title": "Visible Light-Induced Intermolecular Dearomatization for Constructing Angularly Fused Tetracyclic Scaffolds",
"authors": [
"Fan Lin",
"Ting-Ting Song",
"Li-Ming Zhang",
"Zhi-Yuan Ding",
"Yilitabaier Julaiti",
"Yanhua Lu",
"Boshun Wan",
"Yaguang Sun",
"Qing-An Chen"
],
"journal": "Nature Communications",
"url": "https://www.nature.com/articles/s41467-026-75078-6"
},
{
"task_id": "copper-allylic-amination-additive-yield",
"doi": "10.1038/s41467-025-64951-5",
"title": "Light-driven radical copper-catalyzed allylic amination via allylic copper intermediates",
"authors": [
"Hang Luo",
"Yupeng Yang",
"Yunpeng Ma",
"Fangnian Yu",
"Min Gao",
"Shizhao Xu",
"Huawei Ju",
"Yang Li",
"Kaifeng Wu",