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Carrelame is an extremely high potency artificial sweetener of the guanidine class, closely related to lugduname . While carrelame is roughly 200,000 times as sweet as sucrose , lugduname is still somewhat sweeter. [ 1 ] It appears safe in pigs . [ 2 ]
This article about an organic compound is a stub . You can help Wi... | https://en.wikipedia.org/wiki/C22H19Cl2N3O2 |
Cypermethrin ( CP ) is a synthetic pyrethroid used as an insecticide in large-scale commercial agricultural applications as well as in consumer products for domestic purposes. It behaves as a fast-acting neurotoxin in insects. It is easily degraded on soil and plants but can be effective for weeks when applied to indoo... | https://en.wikipedia.org/wiki/C22H19Cl2NO3 |
Tivozanib , sold under the brand name Fotivda , is a medication used for the treatment of advanced renal cell carcinoma (kidney cancer). [ 3 ] It is an oral VEGF receptor tyrosine kinase inhibitor. [ 3 ]
The most common side effects include fatigue (tiredness), hypertension (high blood pressure), diarrhea , decreased ... | https://en.wikipedia.org/wiki/C22H19ClN4O5 |
Atovaquone , sold under the brand name Mepron , is an antimicrobial medication for the prevention and treatment of Pneumocystis jirovecii pneumonia (PCP). [ 2 ]
Atovaquone is a chemical compound that belongs to the class of naphthoquinones . Atovaquone is a hydroxy-1,4-naphthoquinone, an analog of both ubiquinone and ... | https://en.wikipedia.org/wiki/C22H19ClO3 |
CHZ868 is a drug which acts as a Janus kinase inhibitor selective for the JAK2 subtype. It was one of the first Janus kinase inhibitors developed, originally for the treatment of leukemia and related blood cancers, and while it did not get approved for clinical use, it is still used for research in the area. [ 1 ] [ 2 ... | https://en.wikipedia.org/wiki/C22H19F2N5O2 |
Tucidinostat ( INN , also known as chidamide and sold under the brand names Epidaza and Hiyasta ) is a histone deacetylase inhibitor (HDI) developed in China. [ 1 ] It was also known as HBI-8000 . [ 2 ] It is a benzamide HDI and inhibits Class I HDAC1 , HDAC2 , HDAC3 , as well as Class IIb HDAC10 . [ 3 ]
Tucidinostat ... | https://en.wikipedia.org/wiki/C22H19FN4O2 |
GML-1 is a TSPO (peripheral benzodiazepine receptor) ligand with anxiolytic activity. [ 1 ] Its binding affinity (Ki value) to TSPO is comparable with PK11195 . GML-1 is selective for TSPO versus the central benzodiazepine receptor (CBR, GABAA receptor ). The compound GML-1 was the most active of a series of 1-arylpyrr... | https://en.wikipedia.org/wiki/C22H19N3O |
Tadalafil , sold under the brand name Cialis among others, is a medication used to treat erectile dysfunction , benign prostatic hyperplasia , and pulmonary arterial hypertension . [ 4 ] [ 5 ] [ 7 ] It is taken by mouth . [ 7 ] Onset is typically within half an hour and the duration is up to 36 hours. [ 7 ]
Common sid... | https://en.wikipedia.org/wiki/C22H19N3O4 |
Galunisertib (LY2157299) is a small molecular experimental cancer drug previously in development by Eli Lilly . It is a TGF-b inhibitor. [ 1 ] Development of galunisertib by Eli Lilly was discontinued in January 2020. [ 2 ]
Galunisertib was investigated in a phase II trial for treatment of hepatocellular carcinoma . [... | https://en.wikipedia.org/wiki/C22H19N5O |
Bisacodyl is an organic compound that is used as a stimulant laxative drug. It works directly on the colon to produce a bowel movement. It is typically prescribed for relief of episodic and chronic constipation and for the management of neurogenic bowel dysfunction , as well as part of bowel preparation before medical ... | https://en.wikipedia.org/wiki/C22H19NO4 |
Tifluadom is a benzodiazepine derivative with an unusual activity profile. [ 1 ] Unlike most benzodiazepines, tifluadom has no activity at the GABA A receptor , but instead is a selective agonist for the κ-opioid receptor . [ 2 ] It has potent analgesic [ 3 ] and diuretic [ 4 ] effects in animals, and also has sedative... | https://en.wikipedia.org/wiki/C22H20FN3OS |
VU0530244 is a potent , selective , and putatively peripherally restricted serotonin 5-HT 2B receptor antagonist which was first described in 2023. [ 1 ] [ 2 ] [ 3 ] Another similar drug, VU0631019, was also described alongside VU0530244. [ 3 ] They were identified via high-throughput screening (HTS). [ 3 ]
The affini... | https://en.wikipedia.org/wiki/C22H20FN5O |
Oroxindin is a flavone , a type of phenolic chemical compound. It is a wogonoside , more accurately a wogonin glucuronide isolated from Oroxylum indicum (Bignoniaceae), [ 1 ] Bacopa monnieri (Plantaginaceae) and Holmskioldia sanguinea [ 2 ] (Chinese hat plant, Verbenaceae).
This article about an aromatic compound is a... | https://en.wikipedia.org/wiki/C22H20O11 |
Carminic acid (C 22 H 20 O 13 ) is a red glucosidal hydroxyanthrapurin that occurs naturally in some scale insects , such as the cochineal , Armenian cochineal , and Polish cochineal . The insects produce the acid as a deterrent to predators. [ 3 ] An aluminum salt of carminic acid is the coloring agent in carmine , a ... | https://en.wikipedia.org/wiki/C22H20O13 |
Collybolide is a secondary metabolite of the Rhodocollybia maculata mushroom, a basidiomycete fungus that grows on rotting conifer wood. It was previously believed to be a potent and selective kappa- opioid receptor agonist . [ 1 ] However, a total synthesis and independent biological assay determined that collybolide ... | https://en.wikipedia.org/wiki/C22H20O7 |
Durantin A is a bio-active coumarinolignoid isolated from the flowering plant Duranta repens . [ 1 ]
This article about an aromatic compound is a stub . You can help Wikipedia by expanding it . | https://en.wikipedia.org/wiki/C22H20O9 |
AM-251 is an inverse agonist at the CB 1 cannabinoid receptor. AM-251 is structurally very close to rimonabant ; both are biarylpyrazole cannabinoid receptor antagonists . In AM-251, the p - chloro group attached to the phenyl substituent at C-5 of the pyrazole ring is replaced with a p - iodo group. The resulting comp... | https://en.wikipedia.org/wiki/C22H21Cl2IN4O |
Rimonabant (also known as SR141716 ; trade names Acomplia , Zimulti ) [ 3 ] is an anorectic antiobesity drug approved in Europe in 2006 but was withdrawn worldwide in 2008 due to serious psychiatric side effects; it was never approved in the United States. [ 1 ] [ 2 ] Rimonabant is an inverse agonist for the cannabinoi... | https://en.wikipedia.org/wiki/C22H21Cl3N4O |
Sarizotan ( EMD-128,130 ) is a selective 5-HT 1A receptor agonist and D 2 receptor antagonist , [ 1 ] which has antipsychotic effects, [ 2 ] [ 3 ] and has also shown efficacy in reducing dyskinesias resulting from long-term anti-Parkinsonian treatment with levodopa . [ 4 ] [ 5 ] [ 6 ] [ 7 ]
In June 2006, the developer... | https://en.wikipedia.org/wiki/C22H21FN2O |
ANA-12 is a selective , small-molecule non-competitive antagonist of TrkB , the main receptor of brain-derived neurotrophic factor (BDNF). [ 1 ] ANA-12 was originally discovered and developed by Cazorla M. and colleagues at Université Paris and Inserm in 2011. [ 1 ] The compound crosses the blood-brain-barrier and exer... | https://en.wikipedia.org/wiki/C22H21N3O3S |
Icotinib (trade name Conmana ) is a highly selective, first generation epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI). Icotinib is approved for use in China as first-line monotherapy in patients with non-small-cell lung cancer with somatic EGFR mutations.
Icotinib was first synthesized in 2002 b... | https://en.wikipedia.org/wiki/C22H21N3O4 |
Annulenes are monocyclic hydrocarbons that contain the maximum number of non-cumulated or conjugated double bonds (' mancude '). They have the general formula C n H n (when n is an even number) or C n H n +1 (when n is an odd number). The IUPAC accepts the use of 'annulene nomenclature' in naming carbocyclic ring syste... | https://en.wikipedia.org/wiki/C22H22 |
Polyvinylidene chloride , or polyvinylidene dichloride ( PVDC ), is a homopolymer of vinylidene chloride .
Ralph Wiley accidentally discovered polyvinylidene chloride polymer in 1933. [ 2 ] At the time he was a college student who worked part-time at Dow Chemical lab as a dishwasher. [ 3 ] While cleaning laboratory gl... | https://en.wikipedia.org/wiki/C22H22Cl22 |
E-6837 is an orally active, 5-HT 6 agonist developed in an attempt to create an anti-obesity medication .
In cell lines expressing rat 5-HT 6 receptors, it acted as a partial agonist (on presumed silent receptors), while it acted as a full agonist on human 5-HT 6 receptors (which are constitutively active ).
Oral adm... | https://en.wikipedia.org/wiki/C22H22ClN3O2S |
Cinacalcet , sold under the brand name Sensipar among others, is a medication used to treat primary hyperparathyroidism , tertiary hyperparathyroidism and parathyroid carcinoma . [ 4 ] [ 6 ] [ 5 ] Cinacalcet acts as a calcimimetic (i.e., it mimics the action of calcium on tissues ) by allosteric activation of the calci... | https://en.wikipedia.org/wiki/C22H22F3N |
Droperidol / d r oʊ ˈ p ɛ r ɪ d ɔː l / ( Inapsine , Droleptan , Dridol , Xomolix , Innovar [combination with fentanyl ]) is an antidopaminergic drug used as an antiemetic (that is, to prevent or treat nausea) and as an antipsychotic . Droperidol is also often used as a rapid sedative in intensive-care treatment , and w... | https://en.wikipedia.org/wiki/C22H22FN3O2 |
Altanserin is a compound that binds to the 5-HT 2A receptor (5-Hydroxytryptamine ( serotonin ) 2A receptor). Labeled with the isotope fluorine-18 it is used as a radioligand in positron emission tomography (PET) studies of the brain , i.e., studies of the 5-HT 2A neuroreceptors . Besides human neuroimaging studies alta... | https://en.wikipedia.org/wiki/C22H22FN3O2S |
Zoliflodacin (development codes AZD0914 and ETX0914 ) is an experimental antibiotic that is being studied for the treatment of antibiotic resistant Neisseria gonorrhoeae ( gonorrhea ). [ 1 ] It has a novel mechanism of action which involves inhibition of bacterial type II topoisomerases . [ 2 ] Zoliflodacin is being de... | https://en.wikipedia.org/wiki/C22H22FN5O7 |
AM-1241 ( 1-(methylpiperidin-2-ylmethyl)-3-(2-iodo-5-nitrobenzoyl)indole ) is a chemical from the aminoalkylindole family that acts as a potent and selective agonist for the cannabinoid receptor CB 2 , [ 1 ] [ 2 ] with a K i of 3.4 nM at CB 2 and 80 times selectivity over the related CB 1 receptor. [ 3 ] [ 4 ] It has a... | https://en.wikipedia.org/wiki/C22H22IN3O3 |
ABT-239 is an H 3 -receptor inverse agonist developed by Abbott . It has stimulant and nootropic effects, and has been investigated as a treatment for ADHD , Alzheimer's disease , and schizophrenia . [ 1 ] [ 2 ] [ 3 ] [ 4 ] ABT-239 is more active at the human H 3 receptor than comparable agents such as thioperamide , c... | https://en.wikipedia.org/wiki/C22H22N2O |
Ambrisentan , sold under the brand name Letairis among others, is a drug used for the treatment of pulmonary hypertension . [ 2 ] [ 4 ] It is an endothelin receptor antagonist. [ 2 ]
The peptide endothelin constricts muscles in blood vessels, increasing blood pressure. Ambrisentan, which relaxes those muscles, is an e... | https://en.wikipedia.org/wiki/C22H22N2O4 |
Varespladib is an inhibitor of the IIa, V, and X isoforms of secretory phospholipase A2 (sPLA2). [ 1 ] [ 2 ] [ 3 ] The molecule acts as an anti-inflammatory agent by disrupting the first step of the arachidonic acid pathway of inflammation . [ 4 ] From 2006 to 2012, varespladib was under active investigation by Anthera... | https://en.wikipedia.org/wiki/C22H22N2O5 |
Darusentan (LU-135252; HMR-4005) is an endothelin receptor antagonist . [ 1 ] Gilead Colorado, a subsidiary of Gilead Sciences , [ 2 ] under license from Abbott Laboratories , is developing darusentan for the potential treatment of uncontrolled hypertension .
In June 2003, Myogen licensed the compound from Abbott for ... | https://en.wikipedia.org/wiki/C22H22N2O6 |
Metacycline or methacycline is a tetracycline antibiotic . It is used as a precursor in the industrial synthesis of doxycycline hyclate . [ citation needed ]
It has been found to act as an agonist of the human pregnane X receptor ligand-binding domain and to induce CYP3A4 expression in vitro . [ 1 ]
Steroids
This sy... | https://en.wikipedia.org/wiki/C22H22N2O8 |
OPK-88004 (formerly known as LY-2452473 or TT-701 ) is a non-steroidal indole derivative which acts as a selective androgen receptor modulator (SARM). It has been investigated by OPKO Health for the treatment of erectile dysfunction and symptoms associated with benign prostate hyperplasia . [ 1 ] [ 2 ] [ 3 ]
The compo... | https://en.wikipedia.org/wiki/C22H22N4O2 |
Cefpirome is a fourth-generation cephalosporin . Trade names include Cefrom, Keiten, Broact, and Cefir. Cefpirome is considered highly active against Gram-negative bacteria , including Pseudomonas aeruginosa , and Gram-positive bacteria . [ citation needed ]
Bacteroides fragilis , enterococci , Pseudomonas spp. and st... | https://en.wikipedia.org/wiki/C22H22N6O5S2 |
Ceftazidime , sold under the brand name Fortaz among others, is a third-generation cephalosporin antibiotic useful for the treatment of a number of bacterial infections . [ 1 ] [ 4 ] Specifically it is used for joint infections , meningitis , pneumonia , sepsis , urinary tract infections , malignant otitis externa , Ps... | https://en.wikipedia.org/wiki/C22H22N6O7S2 |
Glycitin ( glycitein 7- O -glucoside ) is an isoflavone found in soy, and remains to various degrees in soy products like tofu , soymilk [ 1 ] and soy sauce . [ 2 ] Although glycitin has its own health associated properties (below), it can be transformed to glycitein by human intestinal flora by the action of beta-gluc... | https://en.wikipedia.org/wiki/C22H22O10 |
The molecular formula C 22 H 22 O 11 (molar mass: 462.40 g/mol, exact mass: 462.1162 u) may refer to: | https://en.wikipedia.org/wiki/C22H22O11 |
Podophyllotoxin ( PPT ) is the active ingredient in Podofilox , a medical cream used to treat genital warts and molluscum contagiosum . [ 2 ] It is not recommended for HPV infections without external warts. [ 2 ] It can be applied either by a healthcare provider or the patient themselves. [ 2 ]
Podophyllotoxin is a no... | https://en.wikipedia.org/wiki/C22H22O8 |
Ononin is an isoflavone glycoside, the 7- O -β- D -glucopyranoside of formononetin , [ 1 ] which in turn is the 4'- O -methyl (4'-methoxy) derivative of the parent isoflavone daidzein .
Ononin is a major isoflavone [ 2 ] found in a number of plants and herbs like soybean , [ 3 ] Astragalus root, and Glycyrrhiza uralen... | https://en.wikipedia.org/wiki/C22H22O9 |
BTRX-246040 , also known as LY-2940094 , is a potent and selective nociceptin receptor antagonist which is under development by BlackThorn Therapeutics and Eli Lilly for the treatment of major depressive disorder (MDD). [ 1 ] [ 2 ] [ 3 ] It has demonstrated proof-of-concept clinical efficacy for depression. [ 4 ] As of... | https://en.wikipedia.org/wiki/C22H23ClF2N4O2S |
SM-130686 is a small-molecule drug which acts as a potent, orally-active agonist of the ghrelin/growth hormone secretagogue receptor (GHSR) and growth hormone secretagogue , [ 1 ] with around half the potency of the endogenous agonist ghrelin as a stimulator of growth hormone release. [ 2 ] [ 3 ] It produces dose-depen... | https://en.wikipedia.org/wiki/C22H23ClF3N3O3 |
Loratadine , sold under the brand name Claritin among others, is a medication used to treat allergies . [ 4 ] This includes allergic rhinitis (hay fever) and hives . [ 4 ] It is also available in drug combinations such as loratadine/pseudoephedrine , in which it is combined with pseudoephedrine , a nasal decongestant .... | https://en.wikipedia.org/wiki/C22H23ClN2O2 |
Chlortetracycline (trade name Aureomycin , Lederle Laboratories ) is a tetracycline antibiotic , the first tetracycline to be identified. It was discovered in 1945 at Lederle Laboratories under the supervision of scientist Yellapragada Subbarow and Benjamin Minge Duggar . They were helped by Louis T. Wright , [ 2 ] a s... | https://en.wikipedia.org/wiki/C22H23ClN2O8 |
Losartan , sold under the brand name Cozaar among others, is a medication used to treat high blood pressure (hypertension). [ 4 ] It is in the angiotensin receptor blocker (ARB) family of medication, and is considered protective of the kidneys. Besides hypertension, it is also used in diabetic kidney disease , heart fa... | https://en.wikipedia.org/wiki/C22H23ClN6O |
Roluperidone (former developmental code names MIN-101 , CYR-101 , MT-210 ) is a 5-HT 2A and σ 2 receptor antagonist under development by Minerva Neurosciences for the treatment of schizophrenia . [ 1 ] [ 2 ] [ 3 ] [ 4 ] One of its metabolites also has some affinity for the H 1 receptor . [ 2 ] Pre-clinical findings pro... | https://en.wikipedia.org/wiki/C22H23F2N2O2 |
Lenperone ( Elanone-V ) is a typical antipsychotic of the butyrophenone chemical class . [ 1 ] It was first reported as an anti-emetic in 1974, [ 2 ] and its use in treatment of acute schizophrenia was reported in 1975. [ 1 ] Related early antipsychotic agents include declenperone and milenperone .
Lenperone was never... | https://en.wikipedia.org/wiki/C22H23F2NO2 |
GSK-598809 is a selective dopamine D 3 receptor antagonist that is or was under development for the treatment of substance-related disorders , smoking withdrawal , and eating disorders like binge eating disorder . [ 1 ] [ 2 ] [ 3 ] [ 4 ]
The drug is highly selective for the dopamine D 3 receptor (K i = 6.2 nM) over th... | https://en.wikipedia.org/wiki/C22H23F4N5OS |
Trifluperidol is a typical antipsychotic of the butyrophenone chemical class . It has general properties similar to those of haloperidol , but is considerably more potent by weight, and causes relatively more severe side effects, especially tardive dyskinesia and other extrapyramidal effects. It is used in the treatmen... | https://en.wikipedia.org/wiki/C22H23F4NO2 |
Revaprazan (trade name Revanex ) is a drug that reduces gastric acid secretion which is used for the treatment of gastritis . [ 2 ] It acts as an acid pump antagonist [ 3 ] ( potassium-competitive acid blocker ). Revaprazan is approved for use in South Korea, [ 4 ] but is not approved in Europe or the United States.
T... | https://en.wikipedia.org/wiki/C22H23FN4 |
AM-2233 is a drug that acts as a highly potent full agonist for the cannabinoid receptors , with a K i of 1.8 nM at CB 1 and 2.2 nM at CB 2 as the active ( R ) enantiomer . [ 1 ] It was developed as a selective radioligand for the cannabinoid receptors and has been used as its 131 I derivative for mapping the distribut... | https://en.wikipedia.org/wiki/C22H23IN2O |
Bradanicline ( INN ; [ 1 ] development code TC-5619 ) is a drug which was being developed by Targacept that acts as a partial agonist at the α7 subtype of the neural nicotinic acetylcholine receptors . It showed cognitive enhancing effects in animal studies, and was being developed through a collaboration between Targa... | https://en.wikipedia.org/wiki/C22H23N3O2 |
Cerlapirdine ( USAN ; SAM-531 , WAY-262,531 , PF-05212365 ) is a drug which was under development by Wyeth / Pfizer for the treatment of cognitive disorders associated with Alzheimer's disease and schizophrenia . [ 1 ] In a phase II clinical trial it demonstrated a trend toward efficacy along with a good side effect pr... | https://en.wikipedia.org/wiki/C22H23N3O3S |
Aluminon , the tri ammonium salt of aurintricarboxylic acid , is a dye often used to detect the presence of the aluminium ion in an aqueous solution. Aluminon forms a red complex salt in combination with Al 3+ . [ 1 ]
In addition to its use in qualitative inorganic analysis , aluminon has applications in pigment produ... | https://en.wikipedia.org/wiki/C22H23N3O9 |
Motesanib (AMG 706) is an experimental drug candidate originally developed by Amgen [ 1 ] but later investigated by the Takeda Pharmaceutical Company . It is an orally administered small molecule belonging to angiokinase inhibitor class which acts as an antagonist of VEGF receptors , platelet-derived growth factor rece... | https://en.wikipedia.org/wiki/C22H23N5O |
Roquefortine C is a mycotoxin that belongs to a class of naturally occurring 2,5-diketopiperazines [ 1 ] produced by various fungi , particularly species from the genus Penicillium . [ 2 ] It was first isolated from a strain of Penicillium roqueforti , a species commercially used as a source of proteolytic and lipolyti... | https://en.wikipedia.org/wiki/C22H23N5O2 |
Fenpropathrin , or fenopropathrin , is a widely used pyrethroid insecticide in agriculture and household. [ 1 ] [ 2 ] [ 3 ] [ 4 ] Fenpropathrin is an ingestion and contact synthetic pyrethroid. Its mode of action is similar to other natural ( pyrethrum ) and synthetic pyrethroids where in they interfere with the kineti... | https://en.wikipedia.org/wiki/C22H23NO3 |
Zofenopril ( INN ) is a medication that protects the heart and helps reduce high blood pressure . It is an angiotensin-converting enzyme (ACE) inhibitor . [ 1 ]
In small studies, zofenopril appeared significantly more effective in reducing hypertension than two older antihypertensive drugs , atenolol and enalapril , a... | https://en.wikipedia.org/wiki/C22H23NO4S2 |
CECXG ( 3'-ethyl-LY-341,495 ) is a research drug which acts as a potent and selective antagonist for the group II metabotropic glutamate receptors ( mGluR 2/3 ), with reasonable selectivity for mGluR 3 . While it is some five times less potent than LY-341,495 at mGluR 3 , it has 38x higher affinity for mGluR 3 over mGl... | https://en.wikipedia.org/wiki/C22H23NO5 |
Aureothin is a natural product of a cytotoxic shikimate - polyketide antibiotic with the molecular formula C 22 H 23 NO 6 . [ 2 ] [ 3 ] [ 1 ] Aureothin is produced by the bacterium Streptomyces thioluteus [ 3 ] [ 4 ] that illustrates antitumor, antifungal, and insecticidal activities and the new aureothin derivatives c... | https://en.wikipedia.org/wiki/C22H23NO6 |
Noscapine , also known as narcotine , nectodon , nospen , anarcotine and (archaic) opiane , is a benzylisoquinoline alkaloid of the phthalideisoquinoline structural subgroup, which has been isolated from numerous species of the family Papaveraceae (poppy family). It lacks effects associated with opioids such as sedatio... | https://en.wikipedia.org/wiki/C22H23NO7 |
The molecular formula C 22 H 24 Br 2 N 10 O 2 (molar mass: 620.310 g/mol) may refer to: | https://en.wikipedia.org/wiki/C22H24Br2N10O2 |
ISRIB (short for " integrated stress response inhibitor") is an experimental drug that reverses the effects of eIF2α phosphorylation with an IC 50 of 5 nM . It was discovered in the laboratory of Peter Walter at University of California, San Francisco (UCSF) through a semi-automated screening of a large library of smal... | https://en.wikipedia.org/wiki/C22H24Cl2N2O4 |
Henagliflozin is a pharmaceutical drug for the treatment of type 2 diabetes . [ 1 ] In China, it is approved for adult patients with type 2 diabetes to improve the glycemic control. [ 2 ] [ 3 ]
Henagliflozin, like other drugs of the gliflozin class, inhibits the transporter protein sodium/glucose cotransporter 2 (SGLT... | https://en.wikipedia.org/wiki/C22H24ClFO7 |
Azelastine , sold under the brand name Astelin among others, is a H 1 receptor-blocking medication primarily used as a nasal spray to treat allergic rhinitis (hay fever) and as eye drops for allergic conjunctivitis . [ 4 ] [ 5 ] Other uses may include asthma and skin rashes for which it is taken by mouth. [ 6 ] Onset o... | https://en.wikipedia.org/wiki/C22H24ClN3O |
Azalanstat ( INN , [ 1 ] codenamed RS-21607 ) is an anti-obesity drug acting as a lanosterol 14α-demethylase inhibitor. [ 2 ] [ 3 ]
This drug article relating to the gastrointestinal system is a stub . You can help Wikipedia by expanding it . | https://en.wikipedia.org/wiki/C22H24ClN3O2S |
Balovaptan ( INN Tooltip International Nonproprietary Name ; developmental code name RG7314 ), is a selective small molecule antagonist of the vasopressin V 1A receptor which is under development by Roche for the treatment of post-traumatic stress disorder (PTSD). [ 1 ]
It was in a phase III clinical trial for adults ... | https://en.wikipedia.org/wiki/C22H24ClN5O |
Domperidone , sold under the brand name Motilium among others, is a dopamine antagonist medication which is used to treat nausea and vomiting and certain gastrointestinal problems like gastroparesis (delayed gastric emptying ). It raises the level of prolactin in the human body and is used off label to induce and promo... | https://en.wikipedia.org/wiki/C22H24ClN5O2 |
The molecular formula C 22 H 24 FN 3 O 2 (molar mass: 381.45 g/mol, exact mass: 381.1853 u) may refer to: | https://en.wikipedia.org/wiki/C22H24FN3O2 |
Brivanib alaninate ( INN /USAN) also known as BMS-582664 is an investigational, anti-tumorigenic drug for oral administration. The drug is being developed by Bristol-Myers Squibb for the treatment of hepatocellular carcinoma or HCC (also called malignant hepatoma ), the most common type of liver cancer . Brivanib is no... | https://en.wikipedia.org/wiki/C22H24FN5O4 |
Pipequaline ( INN ; development code PK-8165 ) is an anxiolytic drug that was never marketed. [ 1 ] It possesses a novel chemical structure that is not closely related to other drugs of this type. The drug has a similar pharmacological profile to the benzodiazepine family of drugs, but with mainly anxiolytic properties... | https://en.wikipedia.org/wiki/C22H24N2 |
The molecular formula C 22 H 24 N 2 O 10 (molar mass: 476.438 g/mol) may refer to: | https://en.wikipedia.org/wiki/C22H24N2O10 |
Acrivastine is a medication used for the treatment of allergies and hay fever . It is a second-generation H1-receptor antagonist antihistamine (like its base molecule triprolidine ) and works by blocking histamine H1 receptors . [ 1 ]
This non-sedating [ verification needed ] antihistamine is sold under the brand name... | https://en.wikipedia.org/wiki/C22H24N2O2 |
Apremilast , sold under the brand name Otezla among others, is a medication for the treatment of certain types of psoriasis and psoriatic arthritis . [ 5 ] The drug acts as a selective inhibitor of the enzyme phosphodiesterase 4 (PDE4). [ 5 ] It is taken by mouth . [ 5 ]
Apremilast is indicated in the United States fo... | https://en.wikipedia.org/wiki/C22H24N2O7S |
The molecular formula C 22 H 24 N 2 O 8 (molar mass: 444.43 g/mol, exact mass: 444.1533 u) may refer to: | https://en.wikipedia.org/wiki/C22H24N2O8 |
CUMYL-4CN-BINACA (also known as CUMYL-CYBINACA or SGT-78 ) is an indazole -3-carboxamide based synthetic cannabinoid that has been sold online as a designer drug . [ 3 ] [ 4 ] [ 5 ] [ 6 ] [ 7 ] [ 8 ] It is a potent agonist for cannabinoid receptors CB 1 and CB 2 , with in vitro EC 50 values of 0.58 nM and 6.12 nM, resp... | https://en.wikipedia.org/wiki/C22H24N4O |
Mirfentanil is a fentanyl derivative with strong selectivity for the μ opioid receptor . At lower doses, it antagonizes the analgesic effects of alfentanil and substitutes for naloxone in morphine -treated monkeys; however, it also reverses naloxone-precipitated withdrawal in pigeons trained to discriminate morphine fr... | https://en.wikipedia.org/wiki/C22H24N4O2 |
Pimicotinib (ABSK021), an oral, highly potent and selective small molecule blocker of the colony-stimulating factor 1 receptor (CSF-1R) independently discovered by Abbisko Therapeutics. A number of studies have shown that blocking the CSF-1R signaling pathway could effectively modulate and change macrophage functions, ... | https://en.wikipedia.org/wiki/C22H24N6O3 |
Sakuranin is a flavanone , a type of flavonoid. It is the O - glucoside of sakuranetin . It can be found in Prunus sp. [ 1 ]
This article about an aromatic compound is a stub . You can help Wikipedia by expanding it . | https://en.wikipedia.org/wiki/C22H24O10 |
Diethylstilbestrol diacetate ( DESDA ) (brand name Hormostilboral Stark ) is a synthetic , nonsteroidal estrogen of the stilbestrol group and an ester of diethylstilbestrol (DES) that was introduced for clinical use in the 1940s and was formerly marketed but is now no longer available. [ 1 ] [ 2 ]
This drug article re... | https://en.wikipedia.org/wiki/C22H24O4 |
Brilaroxazine (developmental code name RP5063 ), also known as oxaripiprazole , [ 1 ] [ 2 ] is an investigational atypical antipsychotic which is under development by Reviva Pharmaceuticals for the treatment of neuropsychiatric and inflammatory disorders. [ 3 ] [ 5 ] [ 6 ] [ 7 ] It has currently completed the first of ... | https://en.wikipedia.org/wiki/C22H25Cl2N3O3 |
Clentiazem is a calcium channel blocker . [ 1 ]
It is a chlorine derivative of diltiazem . [ 2 ] | https://en.wikipedia.org/wiki/C22H25ClN2O4S |
Ertugliflozin , sold under the brand name Steglatro , is a medication used for the treatment of type 2 diabetes . [ 3 ] [ 4 ]
The most common side effects include fungal infections of the vagina and other infections of the female reproductive system. [ 4 ]
Ertugliflozin is a sodium/glucose cotransporter 2 (SGLT2) inh... | https://en.wikipedia.org/wiki/C22H25ClO7 |
A-423,579 is one of a range of histamine antagonists developed by Abbott Laboratories which are selective for the H 3 subtype, and have stimulant and anorectic effects in animal studies making them potentially useful treatments for obesity . A-423,579 has improved characteristics over earlier drugs in the series with b... | https://en.wikipedia.org/wiki/C22H25F2N3O |
Nebivolol is a beta blocker used to treat high blood pressure and heart failure . [ 6 ] As with other β-blockers, it is generally a less preferred treatment for high blood pressure. [ 7 ] It may be used by itself or with other blood pressure medication. [ 7 ] It is taken by mouth. [ 7 ]
Common side effects include diz... | https://en.wikipedia.org/wiki/C22H25F2NO4 |
The molecular formula C 22 H 25 FN 4 O 2 (molar mass: 396.458 g/mol, exact mass: 396.1962 u) may refer to: | https://en.wikipedia.org/wiki/C22H25FN4O2 |
Trimetaphan camsilate ( INN ) or trimethaphan camsylate ( USAN ), sold under the trade name Arfonad , is a sympatholytic drug that is infrequently used to lower blood pressure .
Trimetaphan is a ganglionic blocker : it counteracts cholinergic transmission at the a specific type of nicotinic acetylcholine receptors in ... | https://en.wikipedia.org/wiki/C22H25N2OS |
Centhaquine (brand name Lyfaquin ) is a cardiovascular drug. [ 1 ] In India, it is approved for the treatment of hypovolemic shock . [ 2 ]
Centhaquine is a vasopressor that activates α 2A - and α 2B -adrenoreceptors . [ 3 ] It increases venous return and improves tissue perfusion .
This drug article relating to the b... | https://en.wikipedia.org/wiki/C22H25N3 |
The molecular formula C 22 H 25 N 3 O (molar mass: 347.45 g/mol, exact mass: 347.1998 u) may refer to: | https://en.wikipedia.org/wiki/C22H25N3O |
S-14671 is a naphthylpiperazine derivative which acts as a 5-HT 1A receptor agonist (pK i = 9.3) with high efficacy and exceptional in vivo potency , and also as a 5-HT 2A and 5-HT 2C receptor antagonist (both are pK i = 7.8). [ 1 ] [ 2 ] It displays only low and non-significant affinity for 5-HT 1B and 5-HT 3 sites . ... | https://en.wikipedia.org/wiki/C22H25N3O2S |
The molecular formula C 22 H 25 N 3 O 4 (molar mass: 395.452 g/mol, exact mass: 395.1845 u) may refer to: | https://en.wikipedia.org/wiki/C22H25N3O4 |
Ertapenem , sold under the brand name Invanz , is a carbapenem antibiotic medication used for the treatment of infections of the abdomen , the lungs, the upper part of the female reproductive system , and the diabetic foot . [ 7 ] [ 8 ]
The most common side effects include diarrhoea, nausea, headache, and problems aro... | https://en.wikipedia.org/wiki/C22H25N3O7S |
JWH-251 ( 1-pentyl-3-(2-methylphenylacetyl)indole ) is a synthetic cannabinoid from the phenylacetylindole family, which acts as a cannabinoid agonist with about five times selectivity for CB 1 with a K i of 29 nM and 146 nM at CB 2 . Similar to the related 2'-methoxy compound JWH-250 , the 2'- chloro compound JWH-203 ... | https://en.wikipedia.org/wiki/C22H25NO |
The molecular formula C 22 H 25 NO 2 (molar mass: 335.44 g/mol) may refer to: | https://en.wikipedia.org/wiki/C22H25NO2 |
Pitofenone is an antispasmodic .
Pitofenone is typically used in combination with fenpiverinium bromide, and metamizole sodium. Previously produced as Baralgin by Sanofi Aventis , the drug is currently sold in Eastern Europe under various trade names, including Spasmalgon ( Actavis , Bulgaria ), Revalgin (Shreya, Indi... | https://en.wikipedia.org/wiki/C22H25NO4 |
The molecular formula C 22 H 25 NO 5 (molar mass: 383.437 g/mol, exact mass: 383.1733 u) may refer to: | https://en.wikipedia.org/wiki/C22H25NO5 |
Colchicine is a medication used to prevent and treat gout , [ 3 ] [ 4 ] to treat familial Mediterranean fever [ 5 ] and Behçet's disease , [ 6 ] and to reduce the risk of myocardial infarction . [ 7 ] The American College of Rheumatology recommends colchicine, nonsteroidal anti-inflammatory drugs (NSAIDs) or steroids i... | https://en.wikipedia.org/wiki/C22H25NO6 |
Clobetasone ( INN [ 1 ] ) is a corticosteroid used in dermatology , for treating such skin inflammation as seen in eczema , psoriasis and other forms of dermatitis , and ophthalmology . Topical clobetasone butyrate has shown minimal suppression of the hypothalamic–pituitary–adrenal axis . [ 2 ]
It is available as clo... | https://en.wikipedia.org/wiki/C22H26ClFO4 |
Dasatinib , sold under the brand name Sprycel among others, is a targeted therapy medication used to treat certain cases of chronic myelogenous leukemia (CML) and acute lymphoblastic leukemia (ALL). [ 3 ] Specifically it is used to treat cases that are Philadelphia chromosome -positive (Ph+). [ 3 ] It is taken by mouth... | https://en.wikipedia.org/wiki/C22H26ClN7O2S |
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