Add files using upload-large-folder tool

.gitattributes

@@ -1,3 +1,5 @@
 800k_completed_metadata.csv.gz filter=lfs diff=lfs merge=lfs -text
 1M_2012-2025_rnaseq_SRA_metadata.csv.gz filter=lfs diff=lfs merge=lfs -text
 1M_2012-2025_rnaseq_SRA_metadata_v0726.csv.gz filter=lfs diff=lfs merge=lfs -text
+1M_2012-2025_rnaseq_SRA_metadata_v1026.csv filter=lfs diff=lfs merge=lfs -text
+1M_2012-2025_rnaseq_SRA_metadata_v0726.csv filter=lfs diff=lfs merge=lfs -text

.gitignore

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+# Byte-compiled / optimized / DLL files
+__pycache__/
+*.py[cod]
+*$py.class
+
+# C extensions
+*.so
+
+# Distribution / packaging
+.Python
+build/
+develop-eggs/
+dist/
+downloads/
+eggs/
+.eggs/
+lib/
+lib64/
+parts/
+sdist/
+var/
+wheels/
+share/python-wheels/
+*.egg-info/
+.installed.cfg
+*.egg
+MANIFEST
+
+# PyInstaller
+#  Usually these files are written by a python script from a template
+#  before PyInstaller builds the exe, so as to inject date/other infos into it.
+*.manifest
+*.spec
+
+# Installer logs
+pip-log.txt
+pip-delete-this-directory.txt
+
+# Unit test / coverage reports
+htmlcov/
+.tox/
+.nox/
+.coverage
+.coverage.*
+.cache
+nosetests.xml
+coverage.xml
+*.cover
+*.py,cover
+.hypothesis/
+.pytest_cache/
+cover/
+
+# Translations
+*.mo
+*.pot
+
+# Django stuff:
+*.log
+local_settings.py
+db.sqlite3
+db.sqlite3-journal
+
+# Flask stuff:
+instance/
+.webassets-cache
+
+# Scrapy stuff:
+.scrapy
+
+# Sphinx documentation
+docs/_build/
+
+# PyBuilder
+.pybuilder/
+target/
+
+# Jupyter Notebook
+.ipynb_checkpoints
+
+# IPython
+profile_default/
+ipython_config.py
+
+# pyenv
+#   For a library or package, you might want to ignore these files since the code is
+#   intended to run in multiple environments; otherwise, check them in:
+# .python-version
+
+# pipenv
+#   According to pypa/pipenv#598, it is recommended to include Pipfile.lock in version control.
+#   However, in case of collaboration, if having platform-specific dependencies or dependencies
+#   having no cross-platform support, pipenv may install dependencies that don't work, or not
+#   install all needed dependencies.
+#Pipfile.lock
+
+# poetry
+#   Similar to Pipfile.lock, it is generally recommended to include poetry.lock in version control.
+#   This is especially recommended for binary packages to ensure reproducibility, and is more
+#   commonly ignored for libraries.
+#   https://python-poetry.org/docs/basic-usage/#commit-your-poetrylock-file-to-version-control
+#poetry.lock
+
+# pdm
+#   Similar to Pipfile.lock, it is generally recommended to include pdm.lock in version control.
+#pdm.lock
+#   pdm stores project-wide configurations in .pdm.toml, but it is recommended to not include it
+#   in version control.
+#   https://pdm.fming.dev/latest/usage/project/#working-with-version-control
+.pdm.toml
+.pdm-python
+.pdm-build/
+
+# PEP 582; used by e.g. github.com/David-OConnor/pyflow and github.com/pdm-project/pdm
+__pypackages__/
+
+# Celery stuff
+celerybeat-schedule
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+# SageMath parsed files
+*.sage.py
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+# Environments
+.env
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+ENV/
+env.bak/
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+
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+.spyderproject
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+
+# Rope project settings
+.ropeproject
+
+# mkdocs documentation
+/site
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+# mypy
+.mypy_cache/
+.dmypy.json
+dmypy.json
+
+# Pyre type checker
+.pyre/
+
+# pytype static type analyzer
+.pytype/
+
+# Cython debug symbols
+cython_debug/
+
+# PyCharm
+#  JetBrains specific template is maintained in a separate JetBrains.gitignore that can
+#  be found at https://github.com/github/gitignore/blob/main/Global/JetBrains.gitignore
+#  and can be added to the global gitignore or merged into this file.  For a more nuclear
+#  option (not recommended) you can uncomment the following to ignore the entire idea folder.
+#.idea/
+
+venv
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+
+manual_annot_dicts/GRANITE_F1.csv.gz
+manual_annot_dicts/GRANITE_F2.csv.gz
+manual_annot_dicts/GRANITE_F3.csv.gz
+manual_annot_dicts/200K_completed_metadata.csv
+manual_annot_dicts/800k_completed_metadata.csv

1M_2012-2025_rnaseq_SRA_metadata_v0726.csv

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+version https://git-lfs.github.com/spec/v1
+oid sha256:1f12bccd0f9b615f44fc472fca70933b06342ce8cd4faefe957d26ebbc2a99d0
+size 338083182

1M_2012-2025_rnaseq_SRA_metadata_v1026.csv

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+version https://git-lfs.github.com/spec/v1
+oid sha256:1d58b78a4185d944790f64254bd986a1c8c7ca4e081ae571b14f0094f1218af8
+size 264393182

README.md

@@ -1,26 +1,88 @@
----
-pretty_name: "1M RNA-seq SRA Samples Annotations"
-language:
-- en
-license: cc-by-4.0
-tags:
-- biology
-- rnaseq
-- sra
-- metadata
-- annotations
-- bioinformatics
-task_categories:
-- tabular-classification
-- text-classification
----
-
-# 1M RNAseq SRA samples annotations
-
-- 800k_completed_metadata.csv: main metadata table for approximately 800k annotated RNA-seq/SRA samples.
-- 800k_rnaseq_metappuccino_labels.db: SQLite database containing Metappuccino labels and associated structured metadata.
-- manual_dics/: folder containing manual normalization and cross-column remapping dictionaries.
-  - FINAL_pass_unique_biopsy_site_values_mapped_to_uberon_with_cosine.tsv: maps raw biopsy_site values to normalized UBERON anatomical terms.
-  - FINAL_pass_unique_organ_values_mapped_to_uberon_with_cosine.tsv: maps raw organ values to normalized UBERON anatomical terms.
-  - FINAL_pass_unique_disease_values_mapped_to_dot_with_cosine.tsv: maps raw disease values to normalized DOT/DOID disease terms.
-  - global_all_column_remaps_WITH_ONTOLOGY_MAPPING_VALUE_ONLY.tsv: defines cross-column remapping rules for values found in the wrong metadata field.
+# Human SRA RNA-seq Metadata Dataset (2012–2025)
+
+## Overview
+
+This dataset contains standardized metadata for 1 037 214 human RNA-seq runs from 49 246 SRA studies published between 2012 and 2025. Each row represents one unique `run_accession`. The dataset combines run-, study- and sample-level information collected from SRA/ENA and BioSample records, followed by metadata reconstruction, normalization and biological ontology mapping.
+
+All samples were annotated with Metappuccino *(Fiona Hak, Camille Marchet, Daniel Gautheret, Mélina Gallopin, Metappuccino: large language model-driven reconstruction of sequence read archive metadata for cancer research, Bioinformatics, Volume 42, Issue 5, May 2026, btag166, https://doi.org/10.1093/bioinformatics/btag166)*.
+
+The resulting table provides harmonized descriptions of the sequencing protocol, biological material, anatomical origin, disease status, treatment and donor characteristics. It is intended to support large-scale RNA-seq dataset discovery, filtering, quality assessment and construction of biologically defined subsets.
+
+## Main file
+
+`1M_2012-2025_rnaseq_SRA_metadata_v1026.csv`
+
+The file contains:
+
+- over 1 million unique RNA-seq runs
+- 49 246 unique studies
+- one row per `run_accession`
+
+## Dataset construction
+
+Human RNA-seq records published between 2012 and 2025 were collected from public SRA/ENA metadata. Information distributed across run, study and BioSample records was consolidated at the run level. Metadata values were then cleaned and normalized to reduce differences in spelling, formatting and terminology across studies.
+
+Biological annotations include standardized biopsy sites, organs, cell lines, cell types, diseases, treatments and donor attributes. Anatomical terms were mapped to UBERON, cell types to the Cell Ontology, and diseases to the Disease Ontology whenever a sufficiently reliable mapping was available. Cell-line annotations were additionally standardized using Cellosaurus.
+
+The dataset includes bulk, single-cell and spatial RNA-seq experiments. Single-cell samples were further classified as droplet-like, plate-like or unknown when the available protocol metadata allowed this distinction.
+
+No biological subset is imposed in the main file. Healthy and diseased samples, primary tissues and cell lines, cancer and non-cancer samples, and different RNA-selection protocols are retained. 
+
+## Metadata fields
+
+The principal metadata fields are:
+
+- `run_accession`: unique SRA run identifier
+- `study_accession`: associated study or project identifier
+- `instrument_platform`: sequencing platform
+- `library_selection`: normalized RNA-selection protocol
+- `library_strategy`: sequencing strategy
+- `base_count`: number of sequenced bases
+- `sequencing_source`: bulk, spatial or single-cell protocol category
+- `biopsy_site`: anatomical sampling location
+- `bs_uberon_code`: UBERON identifier for the biopsy site
+- `biopsy_type`: type of biological sample
+- `cell_line`: standardized cell-line annotation or primary-tissue status
+- `cell_type`: standardized cell-type annotation
+- `cl_code`: Cell Ontology identifier
+- `organ`: standardized organ annotation
+- `organ_uberon_code`: UBERON identifier for the organ
+- `disease`: standardized disease or health status
+- `do_code`: Disease Ontology identifier
+- `is_cancer`: normalized cancer-status indicator
+- `treatment`: treatment or experimental exposure
+- `treatment_time`: reported treatment duration
+- `response`: reported biological or clinical response
+- `age`: normalized donor age
+- `sex`: normalized donor sex
+- `ethnicity`: normalized donor ethnicity
+
+## Confidence scores
+
+Each reconstructed metadata field is accompanied by a corresponding `conf_<field>` column. Confidence values range from 1 to 5, where 5 represents the highest confidence and 1 the lowest.
+
+`row_confidence_1_5` provides an overall assessment of the biological and structural consistency of the complete row. It considers individual field confidence as well as detected contradictions between annotations.
+
+`confidence_reasons` records the rules or consistency checks responsible for reducing the confidence of a field or row. Confidence scores should be interpreted as quality indicators rather than statistical probabilities.
+
+For applications requiring reliable annotations, a minimum field and row confidence threshold can be applied. The derived datasets provided with this resource generally use a threshold of at least 3.
+
+## Missing values
+
+Missing, unavailable or insufficiently supported metadata are represented by `unknown`. An `unknown` value does not necessarily indicate that the information was absent from every original database record; it may also indicate that the available information could not be mapped or inferred with sufficient reliability.
+
+Ontology codes may also remain `unknown` when the corresponding biological annotation could not be mapped unambiguously.
+
+## Limitations
+
+The dataset is derived from public metadata and therefore depends on the completeness and accuracy of the original SRA, ENA and BioSample records. Some annotations were reconstructed from free-text descriptions and may remain uncertain despite normalization and confidence scoring. Multiple runs may originate from the same biological sample, donor or experimental condition, and a unique `run_accession` should not automatically be interpreted as an independent biological replicate.
+
+The confidence system evaluates metadata reliability and biological consistency but does not assess sequencing-read quality, RNA integrity, batch effects or suitability for a specific downstream analysis. 
+
+## Version
+
+Last version: `v1026`
+
+## Cite
+
+https://huggingface.co/datasets/chumphati/1M_RNAseq_SRA_samples_annotations/tree/main

manual_annot_dicts/AGE_1M_H_1225_manual.csv

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+value,normalized_value,occurrences,decision,category,confidence,reason,source_marker,needs_context
+unknown,unknown,581121,KEEP,age_text,HIGH,"Missing, unclear or non-age description.",,false
+Fetus,fetal,19076,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+Blastocyst stage,blastocyst,11721,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+adult,adult,8287,KEEP,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+Adult,adult,4137,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+Fetus*,fetal,2620,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",original_star_present,false
+not applicable,unknown,1523,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+child,child,640,KEEP,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+newborn,neonatal,450,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+unavailable,unknown,330,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+N A,unknown,310,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+Not applicable,unknown,298,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+infant,infant,292,KEEP,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+Young,young,277,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+--,unknown,250,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+neonatal,neonatal,236,KEEP,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+fetal,fetal,231,KEEP,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+Adult*,adult,221,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",original_star_present,false
+neonate,neonatal,195,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+pediatric,pediatric,180,KEEP,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+young,young,174,KEEP,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+Old,old,167,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+old,old,165,KEEP,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+Children,child,152,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+Calf,unknown,138,UNKNOWN,age_text,HIGH,"Off-column material, culture duration, donor description, or non-human stage.",,false
+Neonatal,neonatal,138,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+fetus,fetal,138,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+Blastocyst stage*,blastocyst,137,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",original_star_present,false
+mixed,mixed ages,134,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+time of birth,neonatal,131,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+Embryonic stage,embryonic,126,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+Embryo,embryonic,117,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+older,older adult,113,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+Non specific,unknown,105,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+Pediatric,pediatric,105,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+"female, Malawian",unknown,102,UNKNOWN,age_text,HIGH,"Off-column material, culture duration, donor description, or non-human stage.",,false
+adults,adult,100,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+full term pregnancy,full-term gestation,87,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+no data,unknown,86,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+Newborn,neonatal,78,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+middle aged,middle-aged,77,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+Late embryonic stage,late embryonic,67,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+adolescents,adolescent,67,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+notaplicable,unknown,63,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+unkown,unknown,63,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+uncollected,unknown,61,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+pooled,unknown,57,UNKNOWN,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+/,unknown,56,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+n a,unknown,54,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+Older adult,older adult,53,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+n.a.,unknown,52,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+post-natal,postnatal,52,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+Full-term placenta tissue,full-term gestation,51,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+not_collected,unknown,51,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+Age Unspecified,unknown,50,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+birth,neonatal,49,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+juvenile,juvenile,43,KEEP,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+Embryonic,embryonic,42,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+pooled samples,unknown,42,UNKNOWN,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+GDPR,unknown,40,UNKNOWN,age_text,HIGH,Not a human age value.,,false
+OLD,old,39,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+Extremely premature infants,extremely preterm infant,37,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+not collect,unknown,37,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+undetermined,unknown,37,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+Fetal,fetal,36,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+Infant,infant,36,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+adulthood,adult,36,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+healthy caucasian,unknown,36,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+missing: control sample,unknown,35,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+not provide,unknown,33,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+Adult humans,adult,30,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+Child,child,30,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+infancy,infant,30,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+unknow,unknown,30,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+non applicable,unknown,29,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+not_applicable,unknown,29,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+Not Applicable,unknown,28,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+adolescent and young adults,adolescent; young adult,28,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+"female, adult",adult,27,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+cell line,unknown,26,UNKNOWN,age_text,HIGH,"Off-column material, culture duration, donor description, or non-human stage.",,false
+miss,unknown,26,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+age at diagnosis,unknown,24,UNKNOWN,age_text,HIGH,Not a human age value.,,false
+no,unknown,24,UNKNOWN,age_text,HIGH,Absent age rather than a biological age.,,false
+Human,unknown,23,UNKNOWN,age_text,HIGH,"Off-column material, culture duration, donor description, or non-human stage.",,false
+Neonate,neonatal,23,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+pooled male and female,unknown,22,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+Anonymous,unknown,21,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+adolescent,adolescent,21,KEEP,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+N.D,unknown,20,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+No,unknown,20,UNKNOWN,age_text,HIGH,Absent age rather than a biological age.,,false
+Older,older adult,20,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+Thir,unknown,20,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+human-identifiable,unknown,20,UNKNOWN,age_text,HIGH,"Off-column material, culture duration, donor description, or non-human stage.",,false
+not collection,unknown,20,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+Age unspecified,unknown,19,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+Han Chinese,unknown,18,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+cells,unknown,18,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+female post menopause,postmenopausal,18,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+logarithmic growth phase,unknown,18,UNKNOWN,age_text,HIGH,"Off-column material, culture duration, donor description, or non-human stage.",,false
+one year,1Y0MO,18,NORMALIZE,age_text,MEDIUM,Explicit spelled-out number and stated unit; weeks/days preserved instead of truncating to months.,,false
+postmenopausal,postmenopausal,18,KEEP,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+senior,older adult,18,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+NO,unknown,17,UNKNOWN,age_text,HIGH,Absent age rather than a biological age.,,false
+"Male, smoker, GEX",unknown,16,UNKNOWN,age_text,HIGH,"Off-column material, culture duration, donor description, or non-human stage.",,false
+N.A,unknown,16,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+childhood,child,16,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+fetal liver / cord blood,fetal,16,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+homo sapien,unknown,16,UNKNOWN,age_text,HIGH,"Off-column material, culture duration, donor description, or non-human stage.",,false
+human sample name SNU GMI P,unknown,16,UNKNOWN,age_text,HIGH,"Off-column material, culture duration, donor description, or non-human stage.",,false
+"male, unknown",unknown,16,UNKNOWN,age_text,HIGH,"Off-column material, culture duration, donor description, or non-human stage.",,false
+missing: human-identifiable,unknown,16,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+mixed samples from multple patients,unknown,16,UNKNOWN,age_text,HIGH,"Off-column material, culture duration, donor description, or non-human stage.",,false
+paediatric,pediatric,16,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+two month,0Y2MO,16,NORMALIZE,age_text,MEDIUM,Explicit spelled-out number and stated unit; weeks/days preserved instead of truncating to months.,,false
+Aged,unknown,15,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+First trimester,first trimester,15,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+aged,unknown,15,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+preterm,preterm,15,KEEP,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+Five-week-old,unknown,14,UNKNOWN,age_text,HIGH,Unquantified unit or unspecified age; do not invent numbers.,,false
+Post menopausal,postmenopausal,14,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+Third trimester,third trimester,14,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+"Male, never-smoker",unknown,13,UNKNOWN,age_text,HIGH,"Off-column material, culture duration, donor description, or non-human stage.",,false
+term,unknown,13,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+#N/A,unknown,12,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+Children*,child,12,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",original_star_present,false
+"Female, never-smoker",unknown,12,UNKNOWN,age_text,HIGH,"Off-column material, culture duration, donor description, or non-human stage.",,false
+Fingerling,unknown,12,UNKNOWN,age_text,HIGH,"Off-column material, culture duration, donor description, or non-human stage.",,false
+Infinite,unknown,12,UNKNOWN,age_text,HIGH,Not a human age value.,,false
+N.A.,unknown,12,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+New Born,neonatal,12,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+New born,neonatal,12,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+Twen,unknown,12,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+adullt,adult,12,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+advanced,unknown,12,UNKNOWN,age_text,HIGH,Not a human age value.,,false
+not applicate,unknown,12,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+not colleted,unknown,12,UNKNOWN,age_text,HIGH,Absent age rather than a biological age.,,false
+unknowable,unknown,12,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+Post-partum,unknown,11,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+anonymous blood donor,unknown,11,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+First instar larval stage,unknown,10,UNKNOWN,age_text,HIGH,"Off-column material, culture duration, donor description, or non-human stage.",,false
+Mixed,mixed ages,10,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+Non ICU Adult,adult,10,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+embryonic,embryonic,10,KEEP,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+not apllicable,unknown,10,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+not appliable,unknown,10,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+unable,unknown,10,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+Japanese male,unknown,9,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+Juvenile,juvenile,9,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+Newborne,neonatal,9,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+adult (donor age not collected),adult (donor age not collected),9,KEEP,age_text,MEDIUM,Specific age or developmental descriptor retained; no safe broader synonym.,,false
+age at the time of sampling,unknown,9,UNKNOWN,age_text,HIGH,Not a human age value.,,false
+female; adult,adult,9,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+immortalized,unknown,9,UNKNOWN,age_text,HIGH,"Off-column material, culture duration, donor description, or non-human stage.",,false
+no collected,unknown,9,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+not applicabale,unknown,9,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+preimplantation-stage embryo,preimplantation embryo,9,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+two days after transfection,unknown,9,UNKNOWN,age_text,HIGH,"Off-column material, culture duration, donor description, or non-human stage.",,false
+x,unknown,9,UNKNOWN,age_text,HIGH,Absent age rather than a biological age.,,false
+E,unknown,8,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+Fout,unknown,8,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+Morula stage,morula,8,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+Post-natal,postnatal,8,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+Third Trimester,third trimester,8,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+cell culture,unknown,8,UNKNOWN,age_text,HIGH,"Off-column material, culture duration, donor description, or non-human stage.",,false
+culture cell,unknown,8,UNKNOWN,age_text,HIGH,"Off-column material, culture duration, donor description, or non-human stage.",,false
+days,unknown,8,UNKNOWN,age_text,HIGH,Unquantified unit or unspecified age; do not invent numbers.,,false
+missing: third party data,unknown,8,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+mixed sample (non-demultiplexed),unknown,8,UNKNOWN,age_text,HIGH,"Off-column material, culture duration, donor description, or non-human stage.",,false
+nd,unknown,8,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+new born,neonatal,8,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+older adult,older adult,8,KEEP,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+pre term,preterm,8,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+second trimester fetal,second trimester fetal,8,KEEP,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+surgery,unknown,8,UNKNOWN,age_text,HIGH,"Off-column material, culture duration, donor description, or non-human stage.",,false
+term infant,term infant,8,KEEP,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+unkowm,unknown,8,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+Early passage,unknown,7,UNKNOWN,age_text,HIGH,"Off-column material, culture duration, donor description, or non-human stage.",,false
+Senior,older adult,7,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+Term placenta,full-term gestation,7,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+Uknown,unknown,7,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+adipocytes and stromal cells,unknown,7,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+not primary,unknown,7,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+pregnant adult female who delivered full,pregnant adult female who delivered full,7,KEEP,age_text,MEDIUM,Specific age or developmental descriptor retained; no safe broader synonym.,,false
+youth,youth,7,KEEP,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+(see supp_cellhashing_barcodes.tsv),unknown,6,UNKNOWN,age_text,HIGH,"Off-column material, culture duration, donor description, or non-human stage.",,false
+Adults,adult,6,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+Blastula with ECM,blastula,6,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+Cell line,unknown,6,UNKNOWN,age_text,HIGH,"Off-column material, culture duration, donor description, or non-human stage.",,false
+Cell lines,unknown,6,UNKNOWN,age_text,HIGH,"Off-column material, culture duration, donor description, or non-human stage.",,false
+Complex data,unknown,6,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+De-identified human control iPSC lines,unknown,6,UNKNOWN,age_text,HIGH,"Off-column material, culture duration, donor description, or non-human stage.",,false
+GV,unknown,6,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+Immortal,unknown,6,UNKNOWN,age_text,HIGH,Not a human age value.,,false
+Logarithmic phase,unknown,6,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+Low passage,unknown,6,UNKNOWN,age_text,HIGH,"Off-column material, culture duration, donor description, or non-human stage.",,false
+MSN neuron,unknown,6,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+MSN progenitor,unknown,6,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+Middle Age,middle-aged,6,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+N,unknown,6,UNKNOWN,age_text,HIGH,Absent age rather than a biological age.,,false
+NOT,unknown,6,UNKNOWN,age_text,HIGH,Absent age rather than a biological age.,,false
+Not applicapable,unknown,6,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+Pediatric; Pediatric,pediatric,6,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+Secretory phase,unknown,6,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+Term delivery,full-term gestation,6,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+Unclear,unknown,6,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+Years,unknown,6,UNKNOWN,age_text,HIGH,Unquantified unit or unspecified age; do not invent numbers.,,false
+a week,unknown,6,UNKNOWN,age_text,HIGH,Unquantified unit or unspecified age; do not invent numbers.,,false
+centuries for trees,unknown,6,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+children and adults,child; adult,6,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+elderly,older adult,6,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+fourth passages,unknown,6,UNKNOWN,age_text,HIGH,"Off-column material, culture duration, donor description, or non-human stage.",,false
+late-passage,unknown,6,UNKNOWN,age_text,HIGH,"Off-column material, culture duration, donor description, or non-human stage.",,false
+long,unknown,6,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+missing: lab stock,unknown,6,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+"not age,it's cells",unknown,6,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+not applicable',unknown,6,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+not colleged,unknown,6,UNKNOWN,age_text,HIGH,Absent age rather than a biological age.,,false
+not colletcted,unknown,6,UNKNOWN,age_text,HIGH,Absent age rather than a biological age.,,false
+not recorded,unknown,6,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+paediatric patients,pediatric,6,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+preschool,preschool,6,KEEP,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+primary,unknown,6,UNKNOWN,age_text,HIGH,Not a human age value.,,false
+seconds,unknown,6,UNKNOWN,age_text,HIGH,Unquantified unit or unspecified age; do not invent numbers.,,false
+stable logarithmic growth phase,unknown,6,UNKNOWN,age_text,HIGH,"Off-column material, culture duration, donor description, or non-human stage.",,false
+various,mixed ages,6,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+weeks,unknown,6,UNKNOWN,age_text,HIGH,Unquantified unit or unspecified age; do not invent numbers.,,false
+years,unknown,6,UNKNOWN,age_text,HIGH,Unquantified unit or unspecified age; do not invent numbers.,,false
+NB,neonatal,5,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+NI,unknown,5,UNKNOWN,age_text,HIGH,Absent age rather than a biological age.,,false
+Teenager,adolescent,5,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+Young Adult,young adult,5,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+embryo/blastocyst-derived cell line,unknown,5,UNKNOWN,age_text,HIGH,"Off-column material, culture duration, donor description, or non-human stage.",,false
+"female, adult, senior",unknown,5,UNKNOWN,age_text,HIGH,"Off-column material, culture duration, donor description, or non-human stage.",,false
+five to six weeks old,unknown,5,UNKNOWN,age_text,HIGH,Unquantified unit or unspecified age; do not invent numbers.,,false
+four years old,4Y0MO,5,NORMALIZE,age_text,MEDIUM,Explicit spelled-out number and stated unit; weeks/days preserved instead of truncating to months.,,false
+not aplicable,unknown,5,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+"pediatric, young adult",pediatric; young adult,5,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+premature,preterm,5,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+term not in labor,full-term gestation,5,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+thirty,30,5,NORMALIZE,age_text,MEDIUM,Number word converted to digits; units not inferred.,,false
+unknown patient age,unknown,5,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+.,unknown,4,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+Fifth generation,unknown,4,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+Gestational twelve week old,unknown,4,UNKNOWN,age_text,HIGH,Unquantified unit or unspecified age; do not invent numbers.,,false
+Human donor A,unknown,4,UNKNOWN,age_text,HIGH,"Off-column material, culture duration, donor description, or non-human stage.",,false
+Immortalized,unknown,4,UNKNOWN,age_text,HIGH,"Off-column material, culture duration, donor description, or non-human stage.",,false
+Infant / Newborn,infant; neonatal,4,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+MII,unknown,4,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+Mixed age,mixed ages,4,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+Primary cells,unknown,4,UNKNOWN,age_text,HIGH,"Off-column material, culture duration, donor description, or non-human stage.",,false
+Second trimester,second trimester,4,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+X,unknown,4,UNKNOWN,age_text,HIGH,Absent age rather than a biological age.,,false
+baseline,unknown,4,UNKNOWN,age_text,HIGH,Not a human age value.,,false
+children,child,4,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+commercial,unknown,4,UNKNOWN,age_text,HIGH,Not a human age value.,,false
+ealry passage organoids,unknown,4,UNKNOWN,age_text,HIGH,"Off-column material, culture duration, donor description, or non-human stage.",,false
+embyonic cell line,unknown,4,UNKNOWN,age_text,HIGH,"Off-column material, culture duration, donor description, or non-human stage.",,false
+fetal liver / neonat,fetal; neonatal,4,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+fetal stage,fetal,4,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+hours,unknown,4,UNKNOWN,age_text,HIGH,Unquantified unit or unspecified age; do not invent numbers.,,false
+inf,unknown,4,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+mid,unknown,4,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+mid gestation,mid-gestation,4,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+misssing,unknown,4,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+months,unknown,4,UNKNOWN,age_text,HIGH,Unquantified unit or unspecified age; do not invent numbers.,,false
+multiple,unknown,4,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+not specified,unknown,4,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+one day before differentiation,unknown,4,UNKNOWN,age_text,HIGH,Unquantified unit or unspecified age; do not invent numbers.,,false
+ot provided,unknown,4,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+peri natal,perinatal,4,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+primary embryonal,embryonic,4,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+quiescent,unknown,4,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+six to eight weeks old,unknown,4,UNKNOWN,age_text,HIGH,Unquantified unit or unspecified age; do not invent numbers.,,false
+twenty-nine,29,4,NORMALIZE,age_text,MEDIUM,Number word converted to digits; units not inferred.,,false
+undisclosed,unknown,4,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+unkonown,unknown,4,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+'not applicable,unknown,3,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+Adult (unknown),adult (unknown),3,NORMALIZE,age_text,MEDIUM,Specific age or developmental descriptor retained; no safe broader synonym.,,false
+Baseline,unknown,3,UNKNOWN,age_text,HIGH,Not a human age value.,,false
+Before treatment,unknown,3,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+Children's Colorado consent (COM-,children's colorado consent (com-,3,NORMALIZE,age_text,MEDIUM,Specific age or developmental descriptor retained; no safe broader synonym.,,false
+ENCC,unknown,3,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+Elderly,older adult,3,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+Embyo,embryonic,3,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+Female; Male,unknown,3,UNKNOWN,age_text,HIGH,"Off-column material, culture duration, donor description, or non-human stage.",,false
+Fifth instar larval stage,unknown,3,UNKNOWN,age_text,HIGH,"Off-column material, culture duration, donor description, or non-human stage.",,false
+Late passage,unknown,3,UNKNOWN,age_text,HIGH,"Off-column material, culture duration, donor description, or non-human stage.",,false
+MI,unknown,3,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+ND,unknown,3,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+Normal,unknown,3,UNKNOWN,age_text,HIGH,Not a human age value.,,false
+Uniform standard,unknown,3,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+differentiation day,unknown,3,UNKNOWN,age_text,HIGH,Unquantified unit or unspecified age; do not invent numbers.,,false
+fertile age,unknown,3,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+fifteen,15,3,NORMALIZE,age_text,MEDIUM,Number word converted to digits; units not inferred.,,false
+fifty-nine,59,3,NORMALIZE,age_text,MEDIUM,Number word converted to digits; units not inferred.,,false
+fifty-six,56,3,NORMALIZE,age_text,MEDIUM,Number word converted to digits; units not inferred.,,false
+long-lived subjects,unknown,3,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+middle-aged,middle-aged,3,KEEP,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+n.a,unknown,3,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+n.d.,unknown,3,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+no differentiation,unknown,3,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+not,unknown,3,UNKNOWN,age_text,HIGH,Absent age rather than a biological age.,,false
+postnatal,postnatal,3,KEEP,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+random donor,unknown,3,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+see final_barcodes.csv,unknown,3,UNKNOWN,age_text,HIGH,"Off-column material, culture duration, donor description, or non-human stage.",,false
+sixty-one,61,3,NORMALIZE,age_text,MEDIUM,Number word converted to digits; units not inferred.,,false
+third trimester fetus,third trimester fetal,3,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+thirty-four,34,3,NORMALIZE,age_text,MEDIUM,Number word converted to digits; units not inferred.,,false
+toddler,toddler,3,KEEP,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+twenties,20s,3,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+twenty-eight,28,3,NORMALIZE,age_text,MEDIUM,Number word converted to digits; units not inferred.,,false
+visit date timepoint months Baseline,unknown,3,UNKNOWN,age_text,HIGH,Unquantified unit or unspecified age; do not invent numbers.,,false
+Childbearing age,childbearing age,2,NORMALIZE,age_text,MEDIUM,Specific age or developmental descriptor retained; no safe broader synonym.,,false
+Human fetal skeletal muscle cell lines,unknown,2,UNKNOWN,age_text,HIGH,"Off-column material, culture duration, donor description, or non-human stage.",,false
+Mixed sample,unknown,2,UNKNOWN,age_text,HIGH,"Off-column material, culture duration, donor description, or non-human stage.",,false
+Multigravida women,unknown,2,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+Neonate larva,neonate larva,2,NORMALIZE,age_text,MEDIUM,Specific age or developmental descriptor retained; no safe broader synonym.,,false
+Neonates,neonatal,2,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+Ped,pediatric,2,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+Unkown,unknown,2,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+XXXX,unknown,2,UNKNOWN,age_text,HIGH,Absent age rather than a biological age.,,false
+adolescents; adults,adolescent; adult,2,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+age unspecified,unknown,2,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+cell lines,unknown,2,UNKNOWN,age_text,HIGH,"Off-column material, culture duration, donor description, or non-human stage.",,false
+iPSC,unknown,2,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+juvenil,juvenile,2,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+mid-aged,middle-aged,2,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+old adult,older adult,2,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+second trimester,second trimester,2,KEEP,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+stable cell culture,unknown,2,UNKNOWN,age_text,HIGH,"Off-column material, culture duration, donor description, or non-human stage.",,false
+twenty-five,25,2,NORMALIZE,age_text,MEDIUM,Number word converted to digits; units not inferred.,,false
+twenty-six,26,2,NORMALIZE,age_text,MEDIUM,Number word converted to digits; units not inferred.,,false
+unspecified age,unknown,2,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+varied,mixed ages,2,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+Commercial control,unknown,1,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+DEEP,unknown,1,UNKNOWN,age_text,HIGH,Not a human age value.,,false
+EARLY,unknown,1,UNKNOWN,age_text,HIGH,Not a human age value.,,false
+Embryo culture (blastocyst stage),blastocyst,1,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+Female Young,female young,1,NORMALIZE,age_text,MEDIUM,Specific age or developmental descriptor retained; no safe broader synonym.,,false
+Foetal,fetal,1,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+HDLEC,unknown,1,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+LATE,unknown,1,UNKNOWN,age_text,HIGH,Not a human age value.,,false
+Mixed Adult Human,adult,1,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+NA (pool of individuals),unknown,1,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+No Data,unknown,1,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+No data,unknown,1,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+Not relevant,unknown,1,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+U,unknown,1,UNKNOWN,age_text,HIGH,Absent age rather than a biological age.,,false
+Undetermined,unknown,1,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+Undifferentiated hESC,unknown,1,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+"female, adult, unknown",adult,1,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+fetus; gestational week,fetal,1,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+full term,full-term gestation,1,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+human,unknown,1,UNKNOWN,age_text,HIGH,"Off-column material, culture duration, donor description, or non-human stage.",,false
+immortal cell line,unknown,1,UNKNOWN,age_text,HIGH,"Off-column material, culture duration, donor description, or non-human stage.",,false
+mature,unknown,1,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+mature reference adult human,adult,1,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+mid gestation fetal brain,mid-gestation fetal,1,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+missing-,unknown,1,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+normal control iPSCs,unknown,1,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+not colected,unknown,1,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+not collected',unknown,1,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+not collected-,unknown,1,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+not determined-,unknown,1,UNKNOWN,age_text,HIGH,"Missing, unclear or non-age description.",,false
+ns,unknown,1,UNKNOWN,age_text,HIGH,Absent age rather than a biological age.,,false
+one week,1W,1,NORMALIZE,age_text,MEDIUM,Explicit spelled-out number and stated unit; weeks/days preserved instead of truncating to months.,,false
+pooled male and female tissue,unknown,1,UNKNOWN,age_text,HIGH,"Off-column material, culture duration, donor description, or non-human stage.",,false
+pre school children,preschool,1,NORMALIZE,age_text,HIGH,"Developmental/life-stage synonym, or obvious missing information.",,false
+replicate,unknown,1,UNKNOWN,age_text,HIGH,"No unambiguous human age, developmental stage or unit.",,false
+six weeks,6W,1,NORMALIZE,age_text,MEDIUM,Explicit spelled-out number and stated unit; weeks/days preserved instead of truncating to months.,,false
+thirty-eight,38,1,NORMALIZE,age_text,MEDIUM,Number word converted to digits; units not inferred.,,false
+thirty-one,31,1,NORMALIZE,age_text,MEDIUM,Number word converted to digits; units not inferred.,,false
+thirty-six,36,1,NORMALIZE,age_text,MEDIUM,Number word converted to digits; units not inferred.,,false
+three monthes,0Y3MO,1,NORMALIZE,age_text,MEDIUM,Explicit spelled-out number and stated unit; weeks/days preserved instead of truncating to months.,,false
+three week old,3W,1,NORMALIZE,age_text,MEDIUM,Explicit spelled-out number and stated unit; weeks/days preserved instead of truncating to months.,,false
+twenty-seven,27,1,NORMALIZE,age_text,MEDIUM,Number word converted to digits; units not inferred.,,false
+two week,2W,1,NORMALIZE,age_text,MEDIUM,Explicit spelled-out number and stated unit; weeks/days preserved instead of truncating to months.,,false
+visit date timepoint months ≤,unknown,1,UNKNOWN,age_text,HIGH,Unquantified unit or unspecified age; do not invent numbers.,,false
+week gestation,unknown,1,UNKNOWN,age_text,HIGH,Unquantified unit or unspecified age; do not invent numbers.,,false
+weeks vitro,unknown,1,UNKNOWN,age_text,HIGH,Unquantified unit or unspecified age; do not invent numbers.,,false

manual_annot_dicts/RESPONSE_1M_H_1225_manual.csv

@@ -0,0 +1,64 @@
+value,normalized_value,occurrences,decision,category,confidence,reason,source_marker,needs_context
+unknown,unknown,567626,KEEP,response,HIGH,User-approved response category/synonym.,,false
+not applicable,not applicable,406034,KEEP,response,HIGH,User-approved response category/synonym.,,false
+success,success,34139,KEEP,response,HIGH,User-approved response category/synonym.,,false
+progressive,progressive,15883,KEEP,response,HIGH,User-approved response category/synonym.,,false
+stable,stable,11067,KEEP,response,HIGH,User-approved response category/synonym.,,false
+non-responder,non-responder,222,KEEP,response,HIGH,User-approved response category/synonym.,,false
+NR,non-responder,187,NORMALIZE,response,HIGH,User-approved response category/synonym.,,false
+responder,responder,165,KEEP,response,HIGH,User-approved response category/synonym.,,false
+no,non-responder,123,NORMALIZE,response,HIGH,User-approved response category/synonym.,,false
+NoResp,non-responder,94,NORMALIZE,response,HIGH,User-approved response category/synonym.,,false
+FIX:C>40IU/dl,unknown,83,UNKNOWN,response,HIGH,"Ambiguous abbreviation, unrelated measurement or outcome without unambiguous response semantics.",,false
+Responder,responder,83,NORMALIZE,response,HIGH,User-approved response category/synonym.,,false
+PD,progressive,82,NORMALIZE,response,HIGH,User-approved response category/synonym.,,false
+Resp,responder,81,NORMALIZE,response,HIGH,User-approved response category/synonym.,,false
+JAKi.R,unknown,80,UNKNOWN,response,HIGH,"Ambiguous abbreviation, unrelated measurement or outcome without unambiguous response semantics.",,false
+CR,success,75,NORMALIZE,response,HIGH,User-approved response category/synonym.,,false
+iCR,unknown,70,UNKNOWN,response,HIGH,"Ambiguous abbreviation, unrelated measurement or outcome without unambiguous response semantics.",,false
+R,unknown,69,UNKNOWN,response,HIGH,"Ambiguous abbreviation, unrelated measurement or outcome without unambiguous response semantics.",,false
+good,unknown,66,UNKNOWN,response,HIGH,"Ambiguous abbreviation, unrelated measurement or outcome without unambiguous response semantics.",,false
+FIX:C<40IU/dl,unknown,61,UNKNOWN,response,HIGH,"Ambiguous abbreviation, unrelated measurement or outcome without unambiguous response semantics.",,false
+independent trial,unknown,60,UNKNOWN,response,HIGH,"Ambiguous abbreviation, unrelated measurement or outcome without unambiguous response semantics.",,false
+PR,responder,59,NORMALIZE,response,HIGH,User-approved response category/synonym.,,false
+Responders,responder,58,NORMALIZE,response,HIGH,User-approved response category/synonym.,,false
+Progressive Disease,progressive,52,NORMALIZE,response,HIGH,User-approved response category/synonym.,,false
+moderate,unknown,51,UNKNOWN,response,HIGH,"Ambiguous abbreviation, unrelated measurement or outcome without unambiguous response semantics.",,false
+No Response (NR),non-responder,50,NORMALIZE,response,HIGH,User-approved response category/synonym.,,false
+aPD1.R,unknown,42,UNKNOWN,response,HIGH,"Ambiguous abbreviation, unrelated measurement or outcome without unambiguous response semantics.",,false
+Stable Disease,stable,36,NORMALIZE,response,HIGH,User-approved response category/synonym.,,false
+SD,stable,34,NORMALIZE,response,HIGH,User-approved response category/synonym.,,false
+nonPR,stable,32,NORMALIZE,response,MEDIUM,"User convention: nonPR means nonprogressive; mapped to stable, not equivalent to RECIST stable disease.",,false
+Complete Response,success,30,NORMALIZE,response,HIGH,User-approved response category/synonym.,,false
+No,non-responder,28,NORMALIZE,response,HIGH,User-approved response category/synonym.,,false
+Non-responders,non-responder,25,NORMALIZE,response,HIGH,User-approved response category/synonym.,,false
+PRCR,responder,23,NORMALIZE,response,HIGH,User-approved response category/synonym.,,false
+Sensitive,sensitive,22,NORMALIZE,response,HIGH,User-approved response category/synonym.,,false
+control,control,21,KEEP,response,HIGH,User-approved response category/synonym.,,false
+Partial Response,responder,20,NORMALIZE,response,HIGH,User-approved response category/synonym.,,false
+Resistant,resistant,20,NORMALIZE,response,HIGH,User-approved response category/synonym.,,false
+nonresponder; progressive disease (PD),progressive,20,NORMALIZE,response,HIGH,User-approved response category/synonym.,,false
+responder; partial response (PR),responder,20,NORMALIZE,response,HIGH,User-approved response category/synonym.,,false
+Non.Reponsder,non-responder,19,NORMALIZE,response,HIGH,User-approved response category/synonym.,,false
+Yes,responder,18,NORMALIZE,response,HIGH,User-approved response category/synonym.,,false
+resistant,resistant,17,KEEP,response,HIGH,User-approved response category/synonym.,,false
+nonresponder,non-responder,16,NORMALIZE,response,HIGH,User-approved response category/synonym.,,false
+Partial response,responder,11,NORMALIZE,response,HIGH,User-approved response category/synonym.,,false
+Positive,unknown,11,UNKNOWN,response,HIGH,"Ambiguous abbreviation, unrelated measurement or outcome without unambiguous response semantics.",,false
+Stable disease,stable,11,NORMALIZE,response,HIGH,User-approved response category/synonym.,,false
+baseline,unknown,11,UNKNOWN,response,HIGH,"Ambiguous abbreviation, unrelated measurement or outcome without unambiguous response semantics.",,false
+sensitive,sensitive,11,KEEP,response,HIGH,User-approved response category/synonym.,,false
+N,non-responder,10,NORMALIZE,response,HIGH,User-approved response category/synonym.,,false
+Negative,unknown,10,UNKNOWN,response,HIGH,"Ambiguous abbreviation, unrelated measurement or outcome without unambiguous response semantics.",,false
+"Responder,Responder,Responder,NonResponder,NonResponder,NonResponder,Responder,NonResponder,Responder,Responder",unknown,10,UNKNOWN,response,HIGH,Mixed responder and nonresponder claims; cannot choose one outcome.,,false
+Y,responder,10,NORMALIZE,response,HIGH,User-approved response category/synonym.,,false
+Non-responder,non-responder,9,NORMALIZE,response,HIGH,User-approved response category/synonym.,,false
+Refractory,resistant,9,NORMALIZE,response,HIGH,User-approved response category/synonym.,,false
+Progressive disease,progressive,8,NORMALIZE,response,HIGH,User-approved response category/synonym.,,false
+Complete remission (CR) after CAR-T cell therapy,success,6,NORMALIZE,response,HIGH,User-approved response category/synonym.,,false
+Inadequate responder,unknown,6,UNKNOWN,response,HIGH,"Ambiguous abbreviation, unrelated measurement or outcome without unambiguous response semantics.",,false
+Progression of disease (PD) after CAR-T cell therapy,progressive,6,NORMALIZE,response,HIGH,User-approved response category/synonym.,,false
+Steroid Resistant,resistant,4,NORMALIZE,response,HIGH,User-approved response category/synonym.,,false
+Steroid Sensitive,sensitive,4,NORMALIZE,response,HIGH,User-approved response category/synonym.,,false
+-,unknown,1,UNKNOWN,response,HIGH,User-approved response category/synonym.,,false
+non-responders,non-responder,1,NORMALIZE,response,HIGH,User-approved response category/synonym.,,false

manual_annot_dicts/SEX_1M_H_1225_manual.csv

@@ -0,0 +1,67 @@
+value,normalized_value,occurrences_v0926_4,occurrences_v1026_BOND_v1,occurrences_v0726,occurrences_v1026_SRA_clean,observed_in_sources,decision,reason,source_marker
+unknown,unknown,518140,464085,450331,464085,v0926_4;v1026_BOND_v1;v0726;v1026_SRA_clean_check,KEEP,Insufficient or mixed/undocumented sex information.,
+female,female,252224,286680,293710,286680,v0926_4;v1026_BOND_v1;v0726;v1026_SRA_clean_check,KEEP,Only female explicitly represented; unknown modifiers discarded.,
+male,male,253294,286400,293171,286400,v0926_4;v1026_BOND_v1;v0726;v1026_SRA_clean_check,KEEP,Only male explicitly represented; unknown modifiers discarded.,
+male*,male,5414,0,0,0,v0926_4,NORMALIZE,Only male explicitly represented; unknown modifiers discarded.,original_star_present
+female*,female,5079,0,0,0,v0926_4,NORMALIZE,Only female explicitly represented; unknown modifiers discarded.,original_star_present
+pooled male and female,unknown,2308,0,0,0,v0926_4,UNKNOWN,Both male and female represented; no single-sex label.,
+male and female,unknown,154,0,0,0,v0926_4,UNKNOWN,Both male and female represented; no single-sex label.,
+mixed,unknown,148,0,0,0,v0926_4,UNKNOWN,Insufficient or mixed/undocumented sex information.,
+"46,xx",female,46,0,0,0,v0926_4,NORMALIZE,XX karyotype per requested mapping (applied as sex convention).,
+"46,xy",male,46,0,0,0,v0926_4,NORMALIZE,XY karyotype per requested mapping (applied as sex convention).,
+1,unknown,45,0,0,0,v0926_4,UNKNOWN,Insufficient or mixed/undocumented sex information.,
+0,unknown,42,0,0,0,v0926_4,UNKNOWN,Insufficient or mixed/undocumented sex information.,
+unknown; male,male,0,20,0,20,v1026_BOND_v1;v1026_SRA_clean_check,NORMALIZE,Only male explicitly represented; unknown modifiers discarded.,
+"45,x",unknown,36,0,0,0,v0926_4,UNKNOWN,Cannot unambiguously assign a single male/female label from this value.,
+missing: control sample,unknown,35,0,0,0,v0926_4,UNKNOWN,Insufficient or mixed/undocumented sex information.,
+female; male; unknown,unknown,0,11,0,11,v1026_BOND_v1;v1026_SRA_clean_check,UNKNOWN,Both male and female represented; no single-sex label.,
+male; female; unknown,unknown,0,10,0,10,v1026_BOND_v1;v1026_SRA_clean_check,UNKNOWN,Both male and female represented; no single-sex label.,
+"mixed, male, and female",unknown,20,0,0,0,v0926_4,UNKNOWN,Both male and female represented; no single-sex label.,
+sex ambiguous,unknown,18,0,0,0,v0926_4,UNKNOWN,Insufficient or mixed/undocumented sex information.,
+female and male,unknown,12,0,0,0,v0926_4,UNKNOWN,Both male and female represented; no single-sex label.,
+female; unknown,female,0,6,0,6,v1026_BOND_v1;v1026_SRA_clean_check,NORMALIZE,Only female explicitly represented; unknown modifiers discarded.,
+"female, male, female, female, male, male, female, female, male, and female",unknown,10,0,0,0,v0926_4,UNKNOWN,Both male and female represented; no single-sex label.,
+"male, female, and male",unknown,7,0,0,0,v0926_4,UNKNOWN,Both male and female represented; no single-sex label.,
+(see supp_cellhashing_barcodes.tsv),unknown,6,0,0,0,v0926_4,UNKNOWN,Insufficient or mixed/undocumented sex information.,
+"female, female, and male",unknown,6,0,0,0,v0926_4,UNKNOWN,Both male and female represented; no single-sex label.,
+intersex,unknown,6,0,0,0,v0926_4,UNKNOWN,Cannot unambiguously assign a single male/female label from this value.,
+mixed male and female,unknown,6,0,0,0,v0926_4,UNKNOWN,Both male and female represented; no single-sex label.,
+mixture,unknown,6,0,0,0,v0926_4,UNKNOWN,Insufficient or mixed/undocumented sex information.,
+missing: lab stock,unknown,5,0,0,0,v0926_4,UNKNOWN,Insufficient or mixed/undocumented sex information.,
+"mix, see plate layout_cw11",unknown,4,0,0,0,v0926_4,UNKNOWN,Insufficient or mixed/undocumented sex information.,
+"mix, see plate layout_cw12",unknown,4,0,0,0,v0926_4,UNKNOWN,Insufficient or mixed/undocumented sex information.,
+"mix, see plate layout_cw13",unknown,4,0,0,0,v0926_4,UNKNOWN,Insufficient or mixed/undocumented sex information.,
+"mix, see plate layout_cw14",unknown,4,0,0,0,v0926_4,UNKNOWN,Insufficient or mixed/undocumented sex information.,
+"mix, see plate layout_mw01",unknown,4,0,0,0,v0926_4,UNKNOWN,Insufficient or mixed/undocumented sex information.,
+"mix, see plate layout_mw02",unknown,4,0,0,0,v0926_4,UNKNOWN,Insufficient or mixed/undocumented sex information.,
+"mix, see plate layout_mw03",unknown,4,0,0,0,v0926_4,UNKNOWN,Insufficient or mixed/undocumented sex information.,
+"mix, see plate layout_mw04",unknown,4,0,0,0,v0926_4,UNKNOWN,Insufficient or mixed/undocumented sex information.,
+"mix, see plate layout_mw05",unknown,4,0,0,0,v0926_4,UNKNOWN,Insufficient or mixed/undocumented sex information.,
+"mix, see plate layout_mw09",unknown,4,0,0,0,v0926_4,UNKNOWN,Insufficient or mixed/undocumented sex information.,
+"mix, see plate layout_mw10",unknown,4,0,0,0,v0926_4,UNKNOWN,Insufficient or mixed/undocumented sex information.,
+"mix, see plate layout_mw11",unknown,4,0,0,0,v0926_4,UNKNOWN,Insufficient or mixed/undocumented sex information.,
+"mix, see plate layout_mw15",unknown,4,0,0,0,v0926_4,UNKNOWN,Insufficient or mixed/undocumented sex information.,
+"mix, see plate layout_mw16",unknown,4,0,0,0,v0926_4,UNKNOWN,Insufficient or mixed/undocumented sex information.,
+"mix, see plate layout_mw17",unknown,4,0,0,0,v0926_4,UNKNOWN,Insufficient or mixed/undocumented sex information.,
+pooled female,female,4,0,0,0,v0926_4,NORMALIZE,Only female explicitly represented; unknown modifiers discarded.,
+women-men,unknown,4,0,0,0,v0926_4,UNKNOWN,Both female and male explicitly represented.,
+-participant cvd890_141: female -participant cvd890_339: male -participant cvd890_921: male -participant cvd890_465: female -participant cvd890_987: male -participant cvd890_790: female -participant cvd890_703: male -participant cvd890_231: female -participant cvd890_324: female -participant cvd890_340: male -participant cvd890_765: female,unknown,3,0,0,0,v0926_4,UNKNOWN,Both male and female represented; no single-sex label.,
+-participant cvd890_340: male -participant cvd890_481: male -participant cvd890_517: female -participant cvd890_516: female -participant cvd890_703: male -participant cvd890_251: female -participant cvd890_141: female -participant cvd890_465: female -participant cvd890_339: male -participant cvd890_994: male -participant cvd890_379: female -participant cvd890_298: female,unknown,3,0,0,0,v0926_4,UNKNOWN,Both male and female represented; no single-sex label.,
+-participant cvd890_379: female -participant cvd890_324: female -participant cvd890_298: female -participant cvd890_765: female -participant cvd890_106: male -participant cvd890_717: female -participant cvd890_516: female -participant cvd890_202: male -participant cvd890_997: male -participant cvd890_987: male -participant cvd890_790: female -participant cvd890_934: female,unknown,3,0,0,0,v0926_4,UNKNOWN,Both male and female represented; no single-sex label.,
+-participant cvd890_994: male -participant cvd890_934: female -participant cvd890_251: female -participant cvd890_997: male -participant cvd890_202: male -participant cvd890_231: female -participant cvd890_921: male -participant cvd890_106: male -participant cvd890_481: male -participant cvd890_517: female -participant cvd890_717: female,unknown,3,0,0,0,v0926_4,UNKNOWN,Both male and female represented; no single-sex label.,
+mixed sex,unknown,3,0,0,0,v0926_4,UNKNOWN,Insufficient or mixed/undocumented sex information.,
+"1 male, 2 female",unknown,2,0,0,0,v0926_4,UNKNOWN,Both male and female represented; no single-sex label.,
+female and female,female,2,0,0,0,v0926_4,NORMALIZE,Only female explicitly represented; unknown modifiers discarded.,
+male and male,male,2,0,0,0,v0926_4,NORMALIZE,Only male explicitly represented; unknown modifiers discarded.,
+"male, female, male, male, and female",unknown,2,0,0,0,v0926_4,UNKNOWN,Both male and female represented; no single-sex label.,
+undisclosed,unknown,2,0,0,0,v0926_4,UNKNOWN,Insufficient or mixed/undocumented sex information.,
+"2 male, 1 female",unknown,1,0,0,0,v0926_4,UNKNOWN,Both male and female represented; no single-sex label.,
+3 female,female,1,0,0,0,v0926_4,NORMALIZE,Only female explicitly represented; unknown modifiers discarded.,
+femal,female,1,0,0,0,v0926_4,NORMALIZE,Unambiguous typographical variant of female.,
+"female, male, and male",unknown,1,0,0,0,v0926_4,UNKNOWN,Both male and female represented; no single-sex label.,
+femaley,female,1,0,0,0,v0926_4,NORMALIZE,Unambiguous typographical variant of female.,
+"male, female, male, and female",unknown,1,0,0,0,v0926_4,UNKNOWN,Both male and female represented; no single-sex label.,
+XX,female,0,0,0,0,explicit_alias_not_observed,NORMALIZE,XX karyotype per requested mapping (applied as sex convention).,
+xx,female,0,0,0,0,explicit_alias_not_observed,NORMALIZE,XX karyotype per requested mapping (applied as sex convention).,
+XY,male,0,0,0,0,explicit_alias_not_observed,NORMALIZE,XY karyotype per requested mapping (applied as sex convention).,
+xy,male,0,0,0,0,explicit_alias_not_observed,NORMALIZE,XY karyotype per requested mapping (applied as sex convention).,