Datasets:
Add centroid-matched timing, exact-envelope train reassignment and vector article
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- wu_20261108_centroid_controls/METHODS_RESULTS_zh.md +75 -0
- wu_20261108_centroid_controls/README.md +62 -0
- wu_20261108_centroid_controls/archive_members.json +2012 -0
- wu_20261108_centroid_controls/assets/figure4_lower.svg +193 -0
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- wu_20261108_centroid_controls/briefing.pdf +3 -0
- wu_20261108_centroid_controls/briefing.pptx +3 -0
- wu_20261108_centroid_controls/dependencies.json +22 -0
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wu_20261108_temporal_dispersion/figures/Figure1.pdf filter=lfs diff=lfs merge=lfs -text
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wu_20261108_temporal_dispersion/manuscript.pdf filter=lfs diff=lfs merge=lfs -text
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wu_20261108_temporal_dispersion/source_data/meshes/BRAIN.glb filter=lfs diff=lfs merge=lfs -text
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wu_20261108_temporal_dispersion/figures/Figure1.pdf filter=lfs diff=lfs merge=lfs -text
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wu_20261108_temporal_dispersion/manuscript.pdf filter=lfs diff=lfs merge=lfs -text
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wu_20261108_temporal_dispersion/source_data/meshes/BRAIN.glb filter=lfs diff=lfs merge=lfs -text
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wu_20261108_centroid_controls/assets/registered_brain.pdf filter=lfs diff=lfs merge=lfs -text
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wu_20261108_centroid_controls/briefing.pdf filter=lfs diff=lfs merge=lfs -text
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wu_20261108_centroid_controls/METHODS_RESULTS_zh.md
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# 当前方法与结论：质心匹配与接点时序交换
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本轮完成22次新模拟：12组局部质心匹配压缩、6组保持细胞输入包络的接点时序交换、2组零循环、2组预先指定的联合细化。重新读取18组原始参考，合计40个独立运行目录、1,280个KC细胞—条件读数，其中704个新增。新增接受波形1,005个，40组共3,714个。所有进程退出码为0。原方案、输入及99个依赖文件在计算前冻结。
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## 吴老师要求下的方法
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继续保持5,177 KC结构底座、原61细胞的32/15/14分类及14细胞未解决问题。网络仍为原32 KC和2个真实被动MBON14，保留真实树、1,926个有向KC循环接点、144个KC→MBON接点的落点和伙伴身份。输入明确分为ALPN(A)、directVPN(V)、operationalLVIN(L)，不将所有上游称为视觉。1,356个候选边界接点中，按原资格定义驱动10个细胞，另22个保持连接。外部E与循环R分开控制，逐细胞保存电位、放电、首响应及缺失潜伏期。
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本轮外部E=1nS，原平衡和float32接点权重、每活跃接点18事件保持不变。主网格KC/MBON段长0.25/0.5µm，dt0.0025ms，起始电位记录0.025ms；预设细化为0.125/0.25µm、0.00125ms、0.0125ms。接受波形判据仍为峰≥0mV、前2ms上升速率≥10mV/ms、间隔≥2ms；计数窗[100,1000)ms，胞体平均窗[100,1100)ms。源阈值事件不替代接受波形。
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## 对照一：固定局部平均到达，改变时间分散度
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对每个种子、细胞、输入家族和时间槽，以原时序平均到达为质心mu，令t_new=round(mu+a×(t−mu),6)。同组接点等权，使用等价的算术均值避免浮点权重尺度影响舍入。a=0和0.5新增，a=1复用原始全幅度参考。a=0表示各细胞/家族在各自原质心内同步，并非全网统一同步。
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输入核验共3,960个组—时间槽检查，最大加权质心偏差5e-07ms，来自六位小数时序精度。这一对照固定均值，改变分散和包络；不是保持包络的干预。
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|输入|种子|局部分散度|总接受波形数|响应细胞/32|
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|---|---|---:|---:|---:|
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|V|20261109|0|0|0|
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|V|20261109|0.5|0|0|
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|V|20261109|1|158|32|
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|V|20261110|0|0|0|
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|V|20261110|0.5|0|0|
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|V|20261110|1|127|32|
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|V|20261111|0|0|0|
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|V|20261111|0.5|0|0|
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|V|20261111|1|187|32|
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|L|20261109|0|0|0|
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|L|20261109|0.5|0|0|
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|L|20261109|1|188|32|
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|L|20261110|0|0|0|
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|L|20261110|0.5|0|0|
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|L|20261110|1|188|32|
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|L|20261111|0|0|0|
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|L|20261111|0.5|0|0|
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|L|20261111|1|159|32|
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## 对照二：保持每个细胞的总输入，交换树上接点时序
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在同细胞、同家族的等权接点中，按预先指定的置换交换完整18事件序列。逐细胞/家族的事件时间与权重集合逐项完全相同，因此相同核下总外部电导包络保持一致；接点接收的时序、局部电压依赖电流和后续循环可以变化。真实突触的落点、方向、伙伴身份没有改变。
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|输入|种子|原始→交换总数|计数变化细胞/32|响应状态变化/32|最大首峰偏移ms|
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|---|---|---|---:|---:|---:|
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|V|20261109|158 → 157|1|0|11.1|
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|V|20261110|127 → 158|31|0|32.2|
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|V|20261111|187 → 128|31|0|18.525|
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|L|20261109|188 → 158|30|0|3.3|
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|L|20261110|188 → 216|30|0|210.75|
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|L|20261111|159 → 188|31|0|56.925|
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六组比较保留全部192个配对细胞—条件读数，其中154项计数、0项响应状态改变。其含义是固定外部总输入下的网络接点时序分配效应；单靠该比较不能定位初始敏感树枝，也不能直接断定存在特殊树突巧合放大机制。
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## 零循环与预设联合细化
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首种子质心压缩V/L另做R=0对照；全部循环连接对象保留，逐接点核验积分电导与电荷为零。零响应条件是响应地板，不能据此再宣称正的循环募集效应。独立全幅度循环开关及其三种子结果保留于主图2和扩展图16。
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|输入|主→细网格总数|状态变化/32|计数变化/32|配对首峰|最大胞体RMS mV|
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|---|---|---:|---:|---:|---:|
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|V|0 → 0|0|0|0|0.005585|
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|L|0 → 0|0|0|0|0.0041699|
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所有32细胞的计数、状态、首峰、胞体均值与完整轨迹均保留。没有接受峰时潜伏期仍记缺失。历史全幅度L的时间/空间敏感性继续单列于扩展图13，没有用当前静默条件替代其检验。
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## 文章、图版与公开证据
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[38页英文论文](exports/manuscript.pdf)、[正文源](manuscript/article.md)、[LaTeX](manuscript/main.tex)、[独立编译Overleaf包](https://huggingface.co/datasets/cyd0806/neuronmimic-data/resolve/main/wu_20261108_centroid_controls/overleaf_submission.zip)、[17页PPTX](https://huggingface.co/datasets/cyd0806/neuronmimic-data/resolve/main/wu_20261108_centroid_controls/briefing.pptx)、[矢量汇报PDF](exports/吴老师汇报_质心匹配与接点时序交换_20261108.pdf)。六张复合主图25子图、20张扩展图；新主图4四个面板区分质心、分散、接点分配与循环，原主图4保留为扩展图18，新扩展图19展示全细胞与输��不变量，20展示预设细化。
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实际FlyWire/Amy Sterling脑及蘑菇体表面的矢量投影、真实骨架与突触继续作为解剖锚点，保留CC BY-NC4.0署名。主图、新扩展图和汇报PDF为矢量；历史扩展图2/4保留5个热图/色条栅格对象。12篇已核验文献与公开生理数据保持各自证据单位。7个Fly-ID留出的固定WT9/经验平均RMSE为35.216/32.723mV，作者QC后4个为15.820/14.192mV；24个QC判定全部重建。本轮新核验2026年Current Biology的电压依赖mAChR-B/KC侧向调制研究（10.1016/j.cub.2026.01.014）及其公开代码、钙成像工作簿和归档标识；另下载校验Zenodo的13表、5.1MB实验源工作簿并随本版数据发布。该机制调节可塑性，不把它等同于当前快速兴奋循环；资源清单见references/PUBLIC_DATA_AND_CODE.md。全文结果驱动写作，同时保留参数迁移这一实测边界。未新增动物或湿实验。
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## 发布与下一步
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本版代码和数据采用授权GitHub分支与HF新前缀`wu_20261108_centroid_controls`，全部历史版本保留。精确提交和对象核验见`metadata/publication_receipt.json`。本轮将平均到达与分散的混杂排除到时序精度，并用保持外部总输入的对照检验树上分配。下一步重点是抑制性反馈、独立膜参数约束及公开功能数据能够识别的预测；本版的细化不等于所有运行条件已数值收敛。稿件供作者评阅，尚未投稿。
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# Centroid-matched timing and spatial train assignment in a fixed mushroom-body network
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Twenty-two new simulations separate local arrival centroids from temporal spread and test the assignment of complete input trains across real synaptic sites at exactly matched per-cell input event measures. Forty raw directories (22 new, 18 distinct original references) yield 1,280 KC readouts, including 704 new, and 1,005 new accepted waveform events. The original32/15/14, real trees, directed synaptic positions, partner identities and every simulated cell remain fixed.
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- [38-page article](exports/manuscript.pdf), [manuscript source](manuscript/article.md), [LaTeX](manuscript/main.tex), [independently compiled Overleaf ZIP](https://huggingface.co/datasets/cyd0806/neuronmimic-data/resolve/main/wu_20261108_centroid_controls/overleaf_submission.zip).
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- [17-slide editable briefing](https://huggingface.co/datasets/cyd0806/neuronmimic-data/resolve/main/wu_20261108_centroid_controls/briefing.pptx), [vector PDF](exports/吴老师汇报_质心匹配与接点时序交换_20261108.pdf), [Chinese methods and findings](当前方法与结论.md).
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- [Six composite main figures and20 Extended Data](figures/), [canonical source tables](source_data/), [audits](validation/), [protocol](protocol.json), [publication receipt](metadata/publication_receipt.json).
|
| 8 |
+
- [Verified public data and code](references/PUBLIC_DATA_AND_CODE.md), including the checksum-verified13-sheet experimental source workbook from the2026lateral-KC study.
|
| 9 |
+
|
| 10 |
+
## Mean-matched spread
|
| 11 |
+
|
| 12 |
+
Each original driven cell/family/slot retains its own original centroid. Reduced scales0/.5 are compared with original scale1;0 is not global synchronization. Every active contact retains18events and its original float32 weight. The maximum weighted mean-arrival error is 5e-07ms. Temporal spread and the local event envelope change together.
|
| 13 |
+
|
| 14 |
+
|输入|种子|局部分散度|总接受波形数|响应细胞/32|
|
| 15 |
+
|---|---|---:|---:|---:|
|
| 16 |
+
|V|20261109|0|0|0|
|
| 17 |
+
|V|20261109|0.5|0|0|
|
| 18 |
+
|V|20261109|1|158|32|
|
| 19 |
+
|V|20261110|0|0|0|
|
| 20 |
+
|V|20261110|0.5|0|0|
|
| 21 |
+
|V|20261110|1|127|32|
|
| 22 |
+
|V|20261111|0|0|0|
|
| 23 |
+
|V|20261111|0.5|0|0|
|
| 24 |
+
|V|20261111|1|187|32|
|
| 25 |
+
|L|20261109|0|0|0|
|
| 26 |
+
|L|20261109|0.5|0|0|
|
| 27 |
+
|L|20261109|1|188|32|
|
| 28 |
+
|L|20261110|0|0|0|
|
| 29 |
+
|L|20261110|0.5|0|0|
|
| 30 |
+
|L|20261110|1|188|32|
|
| 31 |
+
|L|20261111|0|0|0|
|
| 32 |
+
|L|20261111|0.5|0|0|
|
| 33 |
+
|L|20261111|1|159|32|
|
| 34 |
+
|
| 35 |
+
|
| 36 |
+
## Exact-envelope train reassignment
|
| 37 |
+
|
| 38 |
+
Complete trains are permuted among equal-weight contacts within each cell/family using a frozen table. Every per-cell/family weighted event-time multiset remains exact; the sites receiving each train change. Counts, support, latencies and voltage remain separate network readouts.
|
| 39 |
+
|
| 40 |
+
|输入|种子|原始→交换总数|计数变化细胞/32|响应状态变化/32|最大首峰偏移ms|
|
| 41 |
+
|---|---|---|---:|---:|---:|
|
| 42 |
+
|V|20261109|158 → 157|1|0|11.1|
|
| 43 |
+
|V|20261110|127 → 158|31|0|32.2|
|
| 44 |
+
|V|20261111|187 → 128|31|0|18.525|
|
| 45 |
+
|L|20261109|188 → 158|30|0|3.3|
|
| 46 |
+
|L|20261110|188 → 216|30|0|210.75|
|
| 47 |
+
|L|20261111|159 → 188|31|0|56.925|
|
| 48 |
+
|
| 49 |
+
|
| 50 |
+
## Prospective numerical probes
|
| 51 |
+
|
| 52 |
+
Two first-seed centroid-collapse V/L conditions halve maximum cable extent, dt and initiation sample spacing. The same input and detector are retained. The source table includes all64cell-condition pairs and missing onsets.
|
| 53 |
+
|
| 54 |
+
|输入|主→细网格总数|状态变化/32|计数变化/32|配对首峰|最大胞体RMS mV|
|
| 55 |
+
|---|---|---:|---:|---:|---:|
|
| 56 |
+
|V|0 → 0|0|0|0|0.005585|
|
| 57 |
+
|L|0 → 0|0|0|0|0.0041699|
|
| 58 |
+
|
| 59 |
+
|
| 60 |
+
See [REPRODUCIBILITY.md](REPRODUCIBILITY.md) for original dependency restoration and compact figure replay. Main figures, new Extended Data19/20 and delivery briefing PDF contain no raster objects; historical heatmap/colorbar rasters remain explicitly inventoried. Actual anatomical meshes retain source-specific attribution and terms. All prior positive and null results remain with their immutable releases. No additional animals or journal submission.
|
| 61 |
+
|
| 62 |
+
GitHub `ydchen0806/bio_fly_cyber_lateralization`, branch `research/wu-structure-function-20261104`; HF `cyd0806/neuronmimic-data`, additive prefix `wu_20261108_centroid_controls`. Exact revisions and preserved historical objects are in the receipt.
|
wu_20261108_centroid_controls/archive_members.json
ADDED
|
@@ -0,0 +1,2012 @@
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|
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