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Align modality labels with paper table; uppercase HERITAGE; group by modality

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  ---
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  license: cc-by-4.0
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  tags:
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- - biology
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- - genomics
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- - proteomics
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- - graph-neural-networks
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- - benchmarking
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- - omics
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  pretty_name: OmicsGBench — Omics Graph Benchmark
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  task_categories:
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- - tabular-classification
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  size_categories:
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- - n<1K
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  ---
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  # OmicsGBench: Benchmarking Graph Neural Networks on Omics Data
@@ -20,30 +20,30 @@ OmicsGBench is the first benchmark suite for graph-level prediction in the **n
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  ## Datasets
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- This repository contains six preprocessed omics graph classification datasets:
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  | Dataset | Modality | n | p | Task |
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- |---|---|---|---|---|
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- | Heritage | Proteomics | 654 | 4,976 | Exercise responder (binary) |
 
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  | Parkinson's | Transcriptomics | 535 | 21,755 | Cognitive status (binary) |
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  | AddNeuroMed | Transcriptomics | 711 | 17,197 | Clinical diagnosis (3-class) |
 
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  | BRCA | Epigenomics | 640 | 19,049 | Cancer subtype (4-class) |
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- | Tuberculosis | Protein microarray | 561 | 3,814 | Culture negative vs positive |
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- | Smoking | DNA methylation | 464 | 139,125 | Never- vs ever-smoker |
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- Smoking stores 139,125 TSS1500/TSS200 probes. Training keeps one probe per gene, about 20,763 genes.
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  ## Source Data
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- - **Heritage**: Robbins et al. (2021), *Nature Metabolism*. Available via MoTrPAC Data Hub (motrpac-data.org) under CC-BY 4.0.
 
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  - **Parkinson's**: Shamir et al. (2017), *Neurology*. Available via NCBI GEO (GSE99039) under GEO public data access policy.
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  - **AddNeuroMed**: Lovestone et al. (2009). Available via NCBI GEO (GSE63063) under GEO public data access policy.
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- - **BRCA**: Yang et al. (2025), MLOmics, *Scientific Data*. Available on Figshare/Hugging Face under CC-BY 4.0.
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- - **Tuberculosis**: Kunnath-Velayudhan et al. (2010), *PNAS*. Available via NCBI GEO (GSE19433) under GEO public data access policy.
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  - **Smoking**: Tsaprouni et al. (2014), *Epigenetics*. Available via NCBI GEO (GSE50660) under GEO public data access policy.
 
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  ## Preprocessing
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  Datasets share one ingest pipeline: probe-to-gene aggregation where the source is probe-level, and the normalization described in Appendix B of the accompanying paper. Matrices on the Hub are uncorrected. HERITAGE covariate adjustment, AddNeuroMed ComBat, and smoking promoter-probe selection plus median-centering are fit on the training split only.
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- The default evaluation is stratified 5-fold. A 70/15/15 train/val/test split is available as `split_type=fixed`. Parkinson's and tuberculosis keep each batch inside one fold: hybridization date for Parkinson's, country of serum collection for tuberculosis.
 
1
  ---
2
  license: cc-by-4.0
3
  tags:
4
+ - biology
5
+ - genomics
6
+ - proteomics
7
+ - graph-neural-networks
8
+ - benchmarking
9
+ - omics
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  pretty_name: OmicsGBench — Omics Graph Benchmark
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  task_categories:
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+ - tabular-classification
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  size_categories:
14
+ - n<1K
15
  ---
16
 
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  # OmicsGBench: Benchmarking Graph Neural Networks on Omics Data
 
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  ## Datasets
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+ This repository contains six preprocessed omics graph classification datasets, grouped by modality:
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  | Dataset | Modality | n | p | Task |
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+ | --- | --- | --- | --- | --- |
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+ | HERITAGE | Proteomics | 654 | 4,976 | Exercise responder (binary) |
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+ | Tuberculosis | Proteomics | 561 | 3,814 | Culture negative vs positive |
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  | Parkinson's | Transcriptomics | 535 | 21,755 | Cognitive status (binary) |
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  | AddNeuroMed | Transcriptomics | 711 | 17,197 | Clinical diagnosis (3-class) |
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+ | Smoking | Epigenomics | 464 | 139,125 | Never- vs ever-smoker |
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  | BRCA | Epigenomics | 640 | 19,049 | Cancer subtype (4-class) |
 
 
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+ Tuberculosis is a full-proteome antibody microarray (immunoproteomics), where each feature is one *M. tuberculosis* protein. Smoking stores 139,125 TSS1500/TSS200 methylation probes; training keeps one probe per gene, about 20,763 genes.
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  ## Source Data
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+ - **HERITAGE**: Robbins et al. (2021), *Nature Metabolism*. Available via MoTrPAC Data Hub (motrpac-data.org) under CC-BY 4.0.
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+ - **Tuberculosis**: Kunnath-Velayudhan et al. (2010), *PNAS*. Available via NCBI GEO (GSE19433) under GEO public data access policy.
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  - **Parkinson's**: Shamir et al. (2017), *Neurology*. Available via NCBI GEO (GSE99039) under GEO public data access policy.
41
  - **AddNeuroMed**: Lovestone et al. (2009). Available via NCBI GEO (GSE63063) under GEO public data access policy.
 
 
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  - **Smoking**: Tsaprouni et al. (2014), *Epigenetics*. Available via NCBI GEO (GSE50660) under GEO public data access policy.
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+ - **BRCA**: Yang et al. (2025), MLOmics, *Scientific Data*. Available on Figshare/Hugging Face under CC-BY 4.0.
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  ## Preprocessing
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  Datasets share one ingest pipeline: probe-to-gene aggregation where the source is probe-level, and the normalization described in Appendix B of the accompanying paper. Matrices on the Hub are uncorrected. HERITAGE covariate adjustment, AddNeuroMed ComBat, and smoking promoter-probe selection plus median-centering are fit on the training split only.
48
 
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+ The default evaluation is stratified 5-fold. A 70/15/15 train/val/test split is available as `split_type=fixed`. Parkinson's and Tuberculosis keep each batch inside one fold: hybridization date for Parkinson's, country of serum collection for Tuberculosis.