accession stringlengths 6 10 | name stringlengths 6 11 | Full Name stringlengths 1 147 ⌀ | taxon stringlengths 3 46 ⌀ | sequence stringlengths 16 2.75k | function stringlengths 6 5.51k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
A6SRT0 | ENOPH_BOTFB | 2,3-diketo-5-methylthio-1-phosphopentane phosphatase | Botrytis | MEGKPRVKVVLLDIEGTVCPISFVKDILFPYALAALPETLSTQWDSPSFLPYRSAFPPEHASTPDALLSHVRDLMAQDLKIPYLKSLQGYLWLRGYESGELKCPLFPDVYPALKKWRDNGAKICIYSSGSVAAQKLLWRYTTEGDLRSCIWNGLEGDDGRELEGGYWDTVNAGLKQHMASYEKIAKANSALGEVGEWLFLSDNIKEVRAAREAGMKSFVVVREGNAEVTAEEREGQVLVESFAEVEKWVEVTADKA | Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). | A6SRT0 |
Q5HNN1 | HEM1_STAEQ | Glutamyl-tRNA reductase | Staphylococcus | MHFVAISINHRTADVTLREQVAFRDDALRLAHEDLYETKAILENVILSTCNRTEVYAIVDQVHTGRYYIQRFLARSFGFEVDDIKDMSEVKVGDDAVEHLLRVTSGLDSIVLGETQILGQMRDAFFLAQNTGTTGTIFNHLFKQAITFAKKAHSETDIADNAVSVSYAAVELAKKVFGKLKSKHAVVIGAGEMGELSLLNLLGSGISNVTIVNRTLSKAKILAEKHNVSYDSLSALPSLLETTDIVISSTSAEDYIITNSMVKTISETRKLDSLVLIDIAVPRDIEPGIDAITNIFNYDVDDLKDLVDANLRERQLAAET... | Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Q5HNN1 |
A4XLN1 | AROQ_CALS8 | Type II DHQase | Caldicellulosiruptor | MKKILVINGPNLNLLGIREKDIYGSTNYNKLLEIISKKANELNLNTLFFQSNHEGEIIDRIHKALDENIDGIIINPGAYTHYSYAIHDAIKAVNIPTIEVHISNIYAREEFRKRSVIAPACVGQISGFGIKSYIIALYALKEILG | Catalyzes a trans-dehydration via an enolate intermediate. | A4XLN1 |
Q6CUI0 | EFM7_KLULA | Elongation factor methyltransferase 7 | Kluyveromyces | MSDIESLNGGDLFAEPSDFYKPPPEPHFATYTRDDVPESSTSQQKDIKLRLVGSSPLWGHLLWNAGIYTAKHMDSHPEEVQDKLVLELGAAGALPTIIAGLLGARKVVSTDYPDADLISNIQYNVDHNIYGGEELFKDEEKRSKQMANRKVVVEGYIWGNDYEPILKHLPQDQQKFDLIILSDLVFNHTEHAKLFKTTKDLLRENGKALVVFSPHRPWLLENDLAFFKDCEEFGLKSDLIELTHWKPMFDEDEETVEIRSSIYAYYLSHI | S-adenosyl-L-methionine-dependent protein methyltransferase that trimethylates the N-terminal glycine 'Gly-2' of elongation factor 1-alpha, before also catalyzing the mono- and dimethylation of 'Lys-3'. | Q6CUI0 |
Q55574 | PYRE_SYNY3 | Orotate phosphoribosyltransferase | unclassified Synechocystis | MTDLTLAALKTAPLAQVRQYLLHLLATHAYKEGDFILSSGQPSTYYINGKLVTLRAEGALAIGRLLLTELPDQVEAVAGLTLGADPIVSAVSTVSAYEEKPVVALIIRKEAKGHGTKAYIEGPELAPGTKVVVLEDVVTTGKSAMLAVERLRNAGYQVDTVISLVDRQQGGREFYQSQGLTFQALFTIGDIQQVYRQK | Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | Q55574 |
A0A2H5AIY4 | 4CL2_NARPS | 4-coumarate-CoA ligase 2 | Narcissus | MITIAESHPQIHHSPPDTTAPSTPPTATIFRSRLPDIVLSNHLPLHEYLFENTLTSPSPCIISASTGRSYSFAETHLLSRKTASFLSSRCGVRRGGVVMLLLHNCPEFVFSFLGSSMLGAVTTAANPFCTPQEIKKQLLASGATVIITQSAYASKISRDDDVEDLIVVTVSDNELERHAAPPEGCVSFSEVESADEDAVPDAVGVGPEDAVAMPFSSGTTGLPKGVVLTHKSMTSSVGQIVDGENPNLHLRKGEDVLLCVLPLFHIFSLNSVLLCGLRTGAAVVIMARFEMEGMLETIQRWGVSVAAVVPPLVLALAKNP... | Produces CoA thioesters of a variety of hydroxy- and methoxy-substituted cinnamic acids, which are used to synthesize several phenylpropanoid-derived compounds, including anthocyanins, flavonoids, isoflavonoids, coumarins, lignin, suberin and wall-bound phenolics. | A0A2H5AIY4 |
Q5FW60 | MUP20_MOUSE | Major urinary protein 24 | Mus | MKLLVLLLCLGLTLVCVHAEEASSMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENSLALKFHIIINEECSEIFLVADKTEKAGEYSVTYDGSNTFTILKTDYDNYIMIHLINKKDGETFQLMELYGREPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANRCLEARE | Male pheromone which stimulates female sexual attraction to male urinary scent and promotes a strong learned attraction to the airborne urinary odor of an individual male . Promotes spatial learning by rapidly conditioning preference for its remembered location among females and competitor males so that animals prefer ... | Q5FW60 |
A5UKX2 | DNLI_METS3 | Polydeoxyribonucleotide synthase [ATP] | Methanobrevibacter | MKYQELVDVYSALENTTKRLEKTQIISNFLLKLDSTTLEQVGLLILGSIFPAWSDKEIGIGNKLVMQAVGEAVGVTPDKVEDAVRDQGDIGLACISLYAKKSQTTFFSQPLTIDFVFKSLRKLSEKSGARSTKRKIDIILEMLSQASASEAKYLTRTILEELRIGVGEGVVRDAIAQAFNIDKSVVERAMMLTNDLGLIAVVAKEKGEGGLKELNLTPGTPVKPMLAQLAPPIPEIINEMGVAICETKYDGIRLQVHRHSDEIKIFTRRLENITHALPEIVDLFNEYLPHEDYIVEGEVIATRDGNPLSFQNILHRVRRK... | DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. | A5UKX2 |
Q74L95 | RPOB_LACJO | Transcriptase subunit beta | Lactobacillus | MLGHAVNYGSHRTRRSFSRIKEVLKLPNLTDVQTQSYKWFLNEGIREMFDDIMPISDFSGKLSLEFVDYKLLKPKYTLEEARDHDANYSAPLHVTLKLTNHETGEIKTQDVFFGEFPLMTDSGTFVINGAERVIVSQLVRSPGVYYHSDFDKNGRQIFGATVIPNRGAWLEYETDAKDLAYVRIDRTRKLPLTVLIRALGFGSDSEIADMFGESDSIRFTLEKDIHKNPADSRVAEALKDIYERLRPGEPKTTDSSRSLLYARFFDPRRYDLAPVGRYKINKKLSLKNRLLRQTLAETLADPDTGEIIAKKGDVVTHELL... | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Q74L95 |
A4STD7 | DUT_AERS4 | dUTP pyrophosphatase | Aeromonas | MTTQIELKILDARIGTEYPLPAYATPGSAGMDLRALLDAPITLAPGDTILVPTGLAIHIQDPGLCATILPRSGLGHKHGIVLGNLVGLIDSDYQGQLMVSVWNRGNDSFTMQPGERIAQLVIMPVVQASFQLVDEFNQSERGEGGFGSSGRQ | This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | A4STD7 |
P22696 | ESS1_YEAST | Processing/termination factor 1 | Saccharomyces | MPSDVASRTGLPTPWTVRYSKSKKREYFFNPETKHSQWEEPEGTNKDQLHKHLRDHPVRVRCLHILIKHKDSRRPASHRSENITISKQDATDELKTLITRLDDDSKTNSFEALAKERSDCSSYKRGGDLGWFGRGEMQPSFEDAAFQLKVGEVSDIVESGSGVHVIKRVG | Essential PPIase specific for phosphoserine and phosphothreonine N-terminal to the proline residue. Required for efficient pre-mRNA 3'-end processing and transcription termination, probably by inducing conformational changes by proline-directed isomerization in the C-terminal domain (CTD) of RPB1, thereby altering cofa... | P22696 |
Q5Q113 | TXLT3_LASSB | LTx3 | unclassified Lasiodora | MRKITIRALLLCSLLLVFHTSAAAELQAQEGHLMIPGDTDTALETVDDERFFECTFECDIKKEGKPCKPKGCKCDDKDNKDHKKCSGGWRCKLKLCLKF | Is toxic to mice but not to insects. | Q5Q113 |
Q5V4H7 | BACS3_HALMA | Sensory-like rhodopsin | Haloarcula | MAQEIVWYGAGAGAFFVSAVVFVWFAATRGNIRSSFYYLPPIHTSVAGAAYVAMALIAGGQLGDTVSITTLRFADWIVSTPIITYYLARLAGVDTQTRRLAVAANVVMIGVGYGFVSMSGSLRWIAFAVSTVAFIGLLYLYIKTFARKINAATASVRSLFQSLRDLTVVTWSLYPVVYFLGPLGTGIIQAPDLNFLVAVLDTIAKVGFMSILLVRYNSVETFVDSWSVAPAK | Sensory rhodopsin. Associates with an unusual transducer lacking a methyl-accepting transducer domain found in all other photosensory transducers. The chromophore is all-trans-retinal in the dark. | Q5V4H7 |
G2K048 | HRCA_LISM4 | Heat-inducible transcription repressor HrcA | Listeria | MLTERQLLIFRAIIDHFTWTIQPVGSKNLLKEKGLPYSSATIRNEMGVLEEYGFIEKTHSSSGRVPSEKGYRFYVDYLLQPKKLDKSDRQMIRSFFSENYYEMEGLIQNSALMLSDLTNYTSILLGPEATKNHLSGFRFVPINNFQAMLILITDQGHVDNHLVTIPEGTTLSDIERMVNILNERLVGLSLDDLKVQIPMEVKELLGKHVRNYESFMHVFSDSFAQASQQKVYFGGKTNILNQPEFHDINKVREMLHLMEEEQDVYELFRDIPDGLQVKIGRENNNSLMEDCSIITATYNIAGERVGGIVLLGPTRMEYSR... | Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. | G2K048 |
B6YUF8 | MTAD_THEON | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | Thermococcus | MSILIKNGYVVYGENLEVIKADVLIESNKIVEVAKNINKSADTVIDAKGKVVSPGFVNLHTHSPMGLFRGLADDLPLMDWLQDHIWPKEAKLTREYTKVGAYLGALEMIKSGTTTFLDMYFFMDAVAEVTLESGLRGYLSYGMIDLGDPEKTEKEVNEALRIMKFIEGLDSDRVHFVFGPHAPYTCSIALLKEVRRLANEHGKLITIHVSETMAEIGQISERYGKSPVVLLDDIGFFGRDVIIAHGVWLDSRDIQILARHGVTVAHNPASNMKLASGVMPLQRLLNAGVNVGLGTDGSASNNNLDMLDEMKLAALLHKVH... | Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine. | B6YUF8 |
A6VKU4 | NAGZ_ACTSZ | N-acetyl-beta-glucosaminidase | Actinobacillus | MSTLLIDLKGQTLRQEEVELLEHPLVAGLILFTRNFYDRPQIQALVKDIRQRVKKPLLITVDQEGGRVQRFRDGFTKLPAMQSFAALIQEPEQQLATAKEAGWQMAAEMTALDIDLSFAPVLDLGHECKAIGDRSFCSDAESVFRLASAFIDGMHAAGMATTGKHFPGHGHVLADSHLETPFDNRPSAVIFERDIRPFQRLIAQNKLNAVMPAHVIYTDCDDQPASGSKYWLQDILRRKLGFHGAVFSDDLGMKGAGFMGDFVTRSEKALSAGCDLLLLCNEPDGVVQVLDNLKLNESRPHFEARQQRLKTLFKKKSFNW... | Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. | A6VKU4 |
Q7NEW1 | CLPP2_GLOVI | Endopeptidase Clp 2 | Gloeobacter | MSELANYGPGAIRAAYSGDYGFRTPPPDLPSLLLNERIVYLGTPINDVVAELLIAQLLYLESEDNAKPIEIYINSPGVAGFETSAFAVYDTMRHVRMPIKTICLGLAGGFSALLMAAGTKGQRMSLPNSRIILYQPYGGARGQATDINIRAQELLTTKRTLNQLLSIHTGKTVEQIDKDTERLFYMSPQEAVSYGLIDKVLEPSANKLAKLKAVGAPV | Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. | Q7NEW1 |
Q42406 | CP18D_ARATH | Rotamase cyclophilin-5 | Arabidopsis | MSNPRVFFDMSLSGTPIGRIEMELFADTTPNTAENFRALCTGEKGMGKLGKPLHFKGSIFHRVIPGFMCQGGDFTAKNGTGGESIYGAKFKDENFIKKHTGAGILSMANSGPNTNGSQFFICTDKTSWLDGKHVVFGQVVKGLDVVKAIEKVGSDSGKTSKVVTITDCGQLS | PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. | Q42406 |
A5I5M0 | GLPK_CLOBH | Glycerokinase | Clostridium | MEKYIMSLDQGTTSSRCIIFNKKGEIVSVAQKEFTQIYPKAGWVEHDPLEIWGKQAGVAGEALNIARISPEQIAGIGITNQRETTVVWNKRTGMPVYNAIVWQCRRTAGYCDELREKGIDKTIKEKTGLMLDAYFSATKIKWILDNVEGARELAEKGDLLFGNIDTWLIWNMTKGKIHVTDYTNASRTMLFNIHELKWDEELLEILDIPKSMLPEVKPSSCVYGETDEILFGVSIPIAGDAGDQQAALFGQTCFNAGMAKNTYGTGCFLLMNTGEKAVDSKNGLLTTIAVGIDGKVEYALEGSIFIGGAVIQWLRDELRM... | Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate. | A5I5M0 |
C1F3C4 | DXS_ACIC5 | 1-deoxyxylulose-5-phosphate synthase | Acidobacterium | MGNLLNSIHSPADIKHFSVPQLEALAQEIRDRLIQSVARTGGHIGPNLGVVELTIAMHYVFDTPQDRFVFDVSHQAYVHKLLTGRANRFDTLRQPGGLNGFMLRSESQHDSYGAGHAGTALSAALGMAVARDIAGGHEHVVALAGDAAFTNGISFEALNNIADQTRRLIVVLNDNEWSIDRNVGAIARYLHKIVTNEHVSQFHDSAARLLKRIGGPAAANMVRRAEEAAKGMLWPSVLFEEFGLTYYGPIDGHNLSLLIDTFKFLKQQDRPVLLHAITQKGRGFEPALAGQKKFHGLGPFDPETGETSSSGQPTYSEVFA... | Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP). | C1F3C4 |
A4XS59 | NADE_PSEMY | NH(3)-dependent NAD(+) synthetase | Pseudomonas | MSNRQAEIAAALDVVPPFADDAALVAEIERRKTFIKNTLKQSGLKVLVLGISGGVDSTTAGRLAQLSVEELRAETGDTDYRFIAVRLPHNTQHDEHDAQDSLKFVNADEEATVNIAASVIGLSEQVSHLQQLSDARRDFVIGNVKARIRMVAQFTIANANNGLVIGTDHAAEAVMGFFTKFGDGACDLAPLSGLVKHQVRAIAAHLGAPQHLVQKTPTADLEELRPGKPDEEAHGVTYAEIDAFLHGQNVSDEAYATIVRTYDATRHKRELPLVP | Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | A4XS59 |
Q60AM9 | EX7S_METCA | Exodeoxyribonuclease VII small subunit | Methylococcus | MARKPPSFEEALTELEQLVERMEQGNLPLEESLKLFERGIELTRTCQKSLQDAEQKVQILLEENSLPTLKPFRDEP | Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides. | Q60AM9 |
Q07KM5 | RL16_RHOP5 | 50S ribosomal protein L16 | Rhodopseudomonas | MMQPKKTKFRKAHKGRIHGVASSGATLSFGQFGLKAMAPERITARQIEAARRALTRHMKRAGRVWIRIFPDVPVSKKPAEVRMGSGKGSPELWVARVKPGRVIFEIDGVNLQIAREALTLAAAKLPIKTRFVARIAE | Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs. | Q07KM5 |
O23730 | CHS4_BROFI | Naringenin-chalcone synthase 4 | Bromheadia | MAPAMEEIRQAQRAEGPAAVLAIGTSTPPNALYQADYPDYYFRITKSEHLTELKEKFKRMCDKSMIKKRYMYLTEEILKENPNICAFMAPSLDARQDIVVTEVPKLAKEAAVRAIKEWGHPKSRITHLIFCTTSGIDMPGADYQLTRLLGLRPSVNRFMLYQQGCFAGGTVLRLAKDLAENNAGARVLVVCSEITAVTFRGPSESHLDSLVGQALFGDGAAAIIVGSDPDSATERPLFQLVSASQTILPESEGAIDGHLREIGLTFHLLKDVPGLISKNIQKCLLDAFKPLGVHDWNSIFWIAHPGGPAILDQVEIKLGL... | The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin. | O23730 |
O70576 | STAG3_MOUSE | Stromalin-3 | Mus | MPTLWSPSTQHHGSSSGSESSPLQKSVRRAQMALSPCSSSILPCDDRDSQGTAEWDSPSTNEDSDFEDSLRRNVKKRAAKQPPKAVPAAKHRKKQSRIVSSGNGKNESVPSTNYLFDAVKAARSCMQSLVDEWLDNYKQDENAGFLELINFFIRACGCKSTVTPEMFKTMSNSEIIQHLTEEFNEDSGDYPLTAPGPSWKKFQGSFCEFVKTLVYQCQYSLLYDGFPMDDLISLLIGLSDSQVRAFRHTSTLAAMKLMTSLVKVALQLSLHKDNNQRQYEAERNKGPEQRAPERLESLLEKRKEFQENQEDIEGMMNAIF... | Meiosis specific component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, a... | O70576 |
B1KSK4 | KAD_CLOBM | Adenylate monophosphate kinase | Clostridium | MRVILLGPPGAGKGTQAKLISEKFSIPHISTGDIFRANIKEKTPLGIEAKRYMDNGQLVPDEVTIGIVKDRLTKDDCDNGFLLDGFPRTVAQAEALDEFLKGINKELDVALLIKVPEEFILERMTGRRVCTSCGASYHIRFNPPKIEGKCDICDNELIQRKDDTEATVKERLEVYSKQTYPLINYYKDNGIISEVNGTESIDEVFGNISNILGRDK | Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. | B1KSK4 |
Q2P8V2 | FPG_XANOM | DNA-(apurinic or apyrimidinic site) lyase MutM | Xanthomonas | MPELPEVETTLRGLSPHLVGQRIHGVILRRPDLRWPIPEQIERLLPGATITNVRRRAKYLLIDTDAGGSALLHLGMSGSLRVLPGDTLPRAHDHVDISLQNGRVLRFNDPRRFGCLLWQSDIQAHELLAALGPEPLSEAFTGDYLHALAYGRRAPVKTFLMDQAVVVGVGNIYAAESLHCAGISPLREAGKVSLDRYRRLAAAVKDILSYAIRRGGTTLRDFISPDGAPGYFEQELTVYGREGEPCKQCGRVLKHAMIGQRATVWCGSCQR | Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. ... | Q2P8V2 |
A7ZP80 | MENC_ECO24 | o-succinylbenzoic acid synthase | Escherichia | MRSAQVYRWQIPMDAGVVLRDRRLKTRDGLYVCLREGEREGWGEISPLPGFSQETWEEAQSVLLAWVNNWLAGDCELPQMPSVAFGVSCALAELADTLPQAANYRAAPLCNGDPDDLILKLADMPGEKVAKVKVGLYEAVRDGMVVNLLLEAIPDLHLRLDANRAWTPLKGQQFAKYVNPDYRHRIAFLEEPCKTRDDSRAFARETGIAIAWDESLREPDFAFVAEEGVRAVVIKPTLTGSLEKVREQVQAAHALGLTAVISSSIESSLGLTQLARIAAWLTPDTIPGLDTLDLMQAQQVRRWPGSTLPVVEVDALERLL | Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB). | A7ZP80 |
Q5ZRE9 | UBID_LEGPH | Polyprenyl p-hydroxybenzoate decarboxylase | Legionella | MKYSDLRDFIAQLESRELLKRIDYPVSPHLEMTLVSDKVLRSGGPALLFTNTPNYNMPVLTNLFGTVERVALGMGEESIVALREIGKLLAALKEPDPPKGFKDAFSKLPLLKQALNMAPKYVSGAECQTHVWEKDEVDLTLLPIQTCWPGDVAPLITWGLVTTRGPHQSRENMGIYRQQLLSKNKLIMRWLSHRGGALDYQAWQQEYPKERFPVAVTLGADPATILAAVTPVPDTLSEYAFAGLLRGQRTRLTRCIGNDLHVPASAEIVLEGYLEPGNEAPEGPYGDHTGYYNEVQSFPVFTVERITHRDKPIYHSTYTG... | Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis. | Q5ZRE9 |
C5CFS3 | RUVA_KOSOT | Holliday junction ATP-dependent DNA helicase RuvA | Kosmotoga | MIKGVEGEITEISGNEVTLKAGQFYLNILCSTNTIKELSLSAKVHLLTYLSFSADRAPEIYGFKDRAEYNVFLMLLKANKIGPKMALKILSATSPEMLQKMIASKDISGLSRLPGLGKKTAERLVSELYDLVKDYAVEFPKELSDVSEDAVGALTALGFDMTSAKLAVNEVLKEQTVENTQELVRKALRKLNKTR | The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA... | C5CFS3 |
P46153 | GATA6_RAT | GATA-binding factor 6 | Rattus | MALTDGGWCLPKRFGAAAADAGDSGPFPAREPSSPLSPISSSSSSCSRGGDRGPCGASNCRTPQLDTEAVAGPPGRSLLLSPYTSHPFAAAHGAAAPGVAGPGSALSTWEDLLLFTDLDQAATASKLLWSSRGAKLSPFAAEQPEEMYQTLAALSSQGPAAYDGAPGGFVHSAAAAAAAAAAASSPVYVPTTRVGSMLPGLPYLQGAGSGPSNHAGGAGAHPGWPQASADSPPYGGGGAAGGGAAGPGGAGSATAHASARFPYSPSPPMANGAARDPGGYVAAGGAGAGSVSGGGGSLAAMGGREHQYSSLSAARPLNGT... | Transcriptional activator that regulates SEMA3C and PLXNA2. May regulate genes that protect epithelial cells from bacterial infection. Involved in gene regulation specifically in the gastric epithelium. Involved in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression. Binds to BMP response element... | P46153 |
Q3M698 | LIPB_TRIV2 | Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase | Trichormus | MIRSNKPPENSCLLYNKGLMPYLEAHAWQRSLLHQRIDYPNLEDVLILLEHPPVYTLGQGSSLEFLKFDPNQSEFEIHRIERGGEVTYHCPGQLVGYPILNLRRHRQDLHWYLRQLEEVIIRVLAVYGLKGDRLPSLTGVWLEGRKVAAIGIKVSRWITMHGFALNVCPDMTGFGRIVPCGITDKPVGSLAQWIPGITCEEVRVHVVQAFAEVFGLVLVES | Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | Q3M698 |
B7N9Q7 | RIHA_ECOLU | Cytidine/uridine-specific hydrolase | Escherichia | MALPILLDCDPGHDDAIAIVLALASPELDVKAITSSAGNQTPEKTLRNVLRMLTLLNRTDIPVAGGAVKPLMRELIIADNVHGESGLDGPALPEPTFAPQNCTAVELMAKTLRESAEPVTIVSTGPQTNVALLLNSHPELHSKIARIVIMGGAMGLGNWTPAAEFNIYVDPEAAEIVFQSGIPVVMAGLDVTHKAQIHVEDTERFRAIGNPVSTIVAELLDFFLEYHKDEKWGFVGAPLHDPCTIAWLLKPELFTTVERWVGVETQGKYTQGMTVVDYYYLTGNKPNASVMVDVDRQGFVDLLADRLKFYA | Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively. | B7N9Q7 |
P01946 | HBA_RAT | Hemopressin | Rattus | MVLSADDKTNIKNCWGKIGGHGGEYGEEALQRMFAAFPTTKTYFSHIDVSPGSAQVKAHGKKVADALAKAADHVEDLPGALSTLSDLHAHKLRVDPVNFKFLSHCLLVTLACHHPGDFTPAMHASLDKFLASVSTVLTSKYR | Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1 . Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling . | P01946 |
C0ZCK0 | LEUD_BREBN | Isopropylmalate isomerase | Brevibacillus | MNPFVIHTGVVAPLDRVNVDTDAIIPKQFLKRIERSGFGQFLFYEWRFTVDGAPIDSFILNTPAYKESTVLLARNNFGCGSSREHAPWALLDYGFRCVIAPSFADIFYNNCFKNGILPIKLSEEQVDELFNRAESKPNYQLTIDLQEQVVRDNEGLSYPFEVDSYRRYCLLNGLDDIGITLQYEDKIAAYEARR | Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate. | C0ZCK0 |
Q8WBV2 | CYB_OSTNU | Ubiquinol-cytochrome-c reductase complex cytochrome b subunit | Ostrinia | MNIYKPIRKTHPIFKIINGSLIDLPTPSNISSLWNFGSLLAMCLIIQIITGLFLTMYYTANIELAFYSVNYICRNVNYGWLIRTLHANGASFFFICIYIHIGRGIYYESFNLKYTWMVGVIILFLLMATAFMGYVLPWGQMSFWGATVITNLLSAIPYLGTMLVNWIWGGFAIDNATLTRFYTFHFILPFIILMMTMIHLLFLHQTGSNNPLGINSNLDKIPFHPFFTFKDMIGFIIISFLLIFLTLTNPYLLGDPDNFTPANPLVTPIHIQPEWYFLFAYAILRSIPNKLGGVIALIMSILILIILPLTFFKKIQGIQF... | Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is... | Q8WBV2 |
Q93NB7 | HPPA_MYXXA | Pyrophosphate-energized inorganic pyrophosphatase | Myxococcus | MLGGTAVVMTVDAYGPISDNAGGISEMSGLGPEVRAITDELDAVGNTTAAIGKGFAIGSATLTVIALFSAFNLEVNHTRIAAGLPEMSLQLTNPNVIVGLLLGSILPFLVGASTMLAVGRAAGAIVEEIGRQFREIPGLMELKADPDPKKIVDIATKSALQEMVFPGIIAVAAPPLVGYLLGPGALAGLLAGSLVVGATMALYMANAGGAWDNAKKFIEKGKLPGHAKGSAVHKAAVVGDMVGDPFKDTSGPGVAILIKVMSVVSLLVASLIALR | Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane. | Q93NB7 |
Q87AR7 | RLUD_XYLFT | rRNA-uridine isomerase D | Xylella | MLVFMSDDLAGFSRQTTVPDGAAGRRFDAVLAELFPEFSRSRLTEWIKSGDVLLNGVLVRPRDPVYGGEVVWLQVMPDIRTDAVPQDIPLDILYEDEHVFVINKPAGLVVHPGAGNPDGTLVNALLHRDPALAAVPRAGVVHRLDKDTSGVMVVARTLQAQTALVEQLSSRQVHRQYLAVVVSALVSGGTVNAAIERHPRDRLRMEVSDTGKEAVTHYRLRERFRAHTALECRLDTGRTHQIRVHMAHLRHPIVGDRLYGGSLKLPKGGTDALVAMLRGFKRQALHAEVLEFLHPVRALPVRIVAPVPEDLCQLLAALRE... | Responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA. | Q87AR7 |
Q8X769 | FUMC_ECO57 | Iron-independent fumarase | Escherichia | MNTVRSEKDSMGAIDVPADKLWGAQTQRSLEHFRISTEKMPTSLIHALALTKRAAAKVNEDLGLLSEEKASAIRQAADEVLAGQHDDEFPLAIWQTGSGTQSNMNMNEVLANRASELLGGVRGMERKVHPNDDVNKSQSSNDVFPTAMHVAALLALRKQLIPQLKTLTQTLSEKSRAFADIVKIGRTHLQDATPLTLGQEISGWVAMLEHNLKHIEYSLPHVAELALGGTAVGTGLNTHPEYARRVADELAVITCAPFVTAPNKFEALATCDALVQAHGALKGLAASLMKIANDVRWLASGPRCGIGEISIPENEPGSSI... | Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate. | Q8X769 |
A8ER37 | ISPDF_ALIB4 | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | Aliarcobacter | MLDVTLIVLCAGNSTRFEHKTKKQWIRVEDEPLWLNVTKRISSFAKFDKIIVTSHQDELNYMKNFSDDFTFVKGGETRQLSILNSLQFVTTKYVMITDVARACVPQSVIENLLNEKSSADCIVPILNVTDTVVYENDTIDRSNVKLIQTPQLSSTQVLRDALNTPIEFTDESSAIKAIDGKIKYIQGSTFSKKLTLGDELDELPCLKAPSNNFFTGTGFDIHAFEEIKDMYLGGVKLPYEYGFKAHSDGDVLIHSVIDALLGACGAGDIGEFFPDTDDKYKGIDSKLLLGQIVNFINNVGYEIVNVDLTIIAQKPKINPF... | Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a ... | A8ER37 |
Q90WZ1 | BRK1B_BOMMX | Bradykinin | Bombina | MRLWFCLSFFIVLCLEHFPETLADERNVPESEEKTEQYLRDLPKINRKGPRPPGFSPFRGKFHSQSLRDLPKINRKGPRPPGFSPFRGKFHSQSLRDLPKINRKGPRPPGFSPFRGKFHSQSLRDLPKINRKGPRPPGFSPFRGKFHSQSLRDLPKINRKGPRPPGFSPFRGKFHSQSLRDLPKINRKGPRPPGFSPFRGKFHSQSHV | In vitro, produces constriction of guinea pig ileum smooth muscle. May target bradykinin receptors (BDKRB). | Q90WZ1 |
A2C4Y5 | RL6_PROM1 | 50S ribosomal protein L6 | Prochlorococcus | MSRTGKKPISLPEKVDVKFEGLSITVKGPKGELQRTLPNGVSLSKDENFIFVKPINEKRQSREMHGLCRSLVANMVEGVSNGFTKKLEIVGVGSRAQVKGKTLVVSAGYSHPVEVVPPEGITFKVENNTNVIVTGPDKELVGNEAAKIRAIRPPEPYKGKGIKYQGELIIRKAGKSGKT | This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. | A2C4Y5 |
B1XJS6 | RS8_SYNP2 | 30S ribosomal protein S8 | unclassified Synechococcus | MAANDTISDMLTRIRNACMVQHDNTKVPMTRMTRNIAEVLKDEGFIENYTEAGEGIEKHLVISLKYKGRNRQPIIQKLQRVSKPGLRVYSNHKDLPRVLGGIGIAIISTSKGVMTDRQARKEGIGGEILCYVW | One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit. | B1XJS6 |
B3CSI0 | RUVC_ORITI | Holliday junction resolvase RuvC | Orientia | MIILGIDPSLVSTGWGVISISGSIVNYIDSGVIKTVSKDSLVLKLGNISLMIEKLITRFNPFHVAMEEVFINKNYSSSVTLIQARGAIMSVIGRYNIDFSEYAPNKIKKAIVGAGKAEKHQVQQMVKLLMHIKKAISKDESDALATAYTASVNHQIKII | Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | B3CSI0 |
Q9HY16 | PCABP_PSEAE | Putrescine/cadaverine-binding protein | Pseudomonas | MMKKLLLVATLMAGAAQATAAEKLYLFNWNDYIAEDTLKRFEQQCGCELVQEFYSGTEEMMAKLAAGASGYDVIIPTQNAVEALIRKGDLLELDKSRLANLSNEAAGYLDKDFDKGNRYSLPYAFTTTLVGYNKTELDKLGIDPADWSVIFDPAVLEKIKGRVTVMDDPQELFGAALKYLGHSANDTDPQHWKEAQALILAAKPYWAAFNSSSYIKELTLGNIWVAHGYSSDMYQARADAEAAGRAFKVDFALPRQGAVLAIDNMVIHKGSKNPDLAYRFIDFMLDGRNASELTNQIGTGTPNAAALPFIKPEIKTLAAL... | Binds putrescine and cadaverine. | Q9HY16 |
Q4R3W4 | KAD8_MACFA | ATP-AMP transphosphorylase 8 | Macaca | MDSASVPHRIPPEMPQYGEENHIFELMQNMLEQLLIHQPEDPIPFMIQHLHKDNDNVPRIVILGPPASGKTTIAMWLCKHLNSSLLTLENLVLNEFSLTATKAKRLYLQRKTIPSALLVQLIQERLAEEDCVKRGWILDGIPETREQALRIQTLGITPRHVIVLSAPDTVLIERNLGKRIDPQTGEIYHTTFDWPPESEIQNRLMVPEDISELETAQKLLEYHRNIVRVIPSYPKILKVISADQPCVDVFYQALTYVQSNHRTNAPFTPRVLLLGPVGSGKSLQAALLAQKYRLVNVCCGQLLKEAMADRTTFGELIQPF... | Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP. Also displays broad nucleoside diphosphate kinase activity. | Q4R3W4 |
Q3B2T3 | HRCA_CHLL3 | Heat-inducible transcription repressor HrcA | Pelodictyon | MGSRELNLRERQVLGIIIQLYVVTAAPVGSRYIARNYSLGLSDATIRNVMADLEAEGYISQPHTSAGRIPTDLGYRYYVDLIMKVQRIDEEEKRRMESDFGPISMEGRGTSAEVLVSAAKVLGSISRQLSVVLSPTLSNAVFEKLDMVLLSSTRMMVVLSIQSMFVKTIVMELQHELTRQKVDEVVDLLNERLSGLTLSEIRRSITRRLAGSSCDTNLKDLIVRSADSLFDESPIFERLYISGAEYIVEQPEFKQPERVRELITMIEDKFSVARLVEDIAPKQDLKRTAGHDVSISIGRENSALQAEDLTIVSAPYYAGS... | Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. | Q3B2T3 |
Q8K9V0 | KHSE_BUCAP | Homoserine kinase | Buchnera | MIKIYAPASVANVGVGFDILGAAIIPINGTLLGDCVTVKLSKKFELINKGIFSNKLPINKEQNIVWKCWFKFCKVIKKNIPVSIILEKNMPIGSGLGSSACSVVATLVAINQICNNPLNSKELLLLMGEIEGEISGSIHYDNVAPSYLGGLQLILEDSDIISQKIPNFKHWFWIIAWPGIKVSTAEARKILPKEYKKDICIKNSRYLAGFIHASYTKQSHLAARCMQDFIAEPYRSKLLPNFLNAKEKIKKIGAISCGISGSGPTIFAISDKIKTAEKISLWLKNNYLQNKTGFVHICAVDVKGVRKIG | Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate. | Q8K9V0 |
P21374 | ISY1_YEAST | PRP19-associated complex protein 30 | Saccharomyces | MSRNVDKANSVLVRFQEQQAESAGGYKDYSRYQRPRNVSKVKSIKEANEWKRQVSKEIKQKSTRIYDPSLNEMQIAELNDELNNLFKEWKRWQWHIDHTLMEKKTKRKRLEDSHVLMNSGKLINGKRYFGRALELPEVKEWLKQSQRQNDGGSINTKCIPKDRNDFYYHGKVTAALTEFEANWTSILKAHYNVPVNEDEEEMSRQTQEIHVPTLADMEHWLVQRRKKKLMDELNL | Involved in pre-mRNA splicing and cell cycle control. As a component of the NTC complex (or PRP19-associated complex), associates to the spliceosome to mediate conformational rearrangement or to stabilize the structure of the spliceosome after U4 snRNA dissociation, which leads to spliceosome maturation. The cell cycle... | P21374 |
B8F634 | AROE_GLAP5 | Shikimate dehydrogenase (NADP(+)) | Glaesserella | MNQYAVWGNPIAQSKSPRIHTLFGQQTGKAISYVAKLGDEQQFEQQLKQFFAEGAKGANITAPFKERAFALADLYSESCLQAEACNTLKRLDDGRLYADNTDGVGLVSDLARLGWPKPHQRILILGAGGATKGVLYPLLQAQQQITIYNRTADKAASLAKKFAKFGQIQSACFDELPEQSFDLIINATSLGLQGKCVELPARLLTQANIYDMQYAPNMQTPFLEYARSQGATQYQDGLGMLVGQAAYTFQLWEDVLPDVEPILKQIKQEMEF | Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | B8F634 |
A8AI14 | PYRC_CITK8 | Dihydroorotase | Citrobacter | MTAPSQVLKIRRPDDWHVHLRDGDMLKTVVPYTSEIYGRAIVMPNLAPPVTTVDAAIAYRQRILDAVPAGHDFTPLMTCYLTDTLDPDELERGFREGVFTAAKLYPANATTNSSHGVTSVDTIMPVLERMEKLGMPLLVHGEVTHADIDIFDREARFIETVMEPLRQRLTALKVVFEHITTKDAAEYVRDGNELLAATITPQHLMFNRNHMLVGGIRPHLYCLPILKRNVHQQALRELVASGFSRAFLGTDSAPHARHRKETSCGCAGCFNAPTALGSYATVFEEMNALAHFEAFCSLNGPRFYGLSVNETYVELVREEQ... | Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. | A8AI14 |
P73648 | GLMM_SYNY3 | Phosphoglucosamine mutase | unclassified Synechocystis | MVASPIHSRGLDLPLPSTMGEFGLSLPRSPLFGTDGIRGKAGELLTAPLALSLGFWAGQVLREQTDTAGPVIIGQDSRLSSDMLANAMAAGLNSAGVEVWQLGLCPTPCVAYLTRKTAAIGGIMISASHNPPEDNGIKFFDHQGLKLPKSLATAIEAGLRGQNQTSGLNASQWGRSYGQPHRVQYYQDFLLGSLPQPLNFQGLKVVLDLAWGASVNLAPHIFRSLGAEVIALHDLADGSQINVDCGSTHLHRLQRAVRETGADLGFAFDGDADRVMAVDAQGRPVDGDYILFLWGKTLQESNHLPDNLIVGTVMANLAFE... | Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. | P73648 |
Q2JMP3 | CHLL_SYNJB | Light-independent protochlorophyllide reductase iron-sulfur ATP-binding protein | unclassified Synechococcus | MEERAVKLAVYGKGGIGKSTTSCNISVALARRGKKVLQIGCDPKHDSTFTLTGFLIPTIIDTLEAKGYHHEDIYPEDVIYRGYGGVDCVEAGGPPAGAGCGGYVVGETVKLLKELNAFDEYDVILFDVLGDVVCGGFAAPLNYADYCLIVTDNGFDALFAANRIAASVREKAKTRKLRLAGLIGNRTSKRDLIDKYVSAVPMPVIEVLPLIEDIRVSRVKGKTLFEMAETDPSLEPVCQYYLNIADELLARPEGIVPQPAEDRELFALLSDFYNTPARQLALV | Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The L component serves as a unique electron donor to the NB-component of the complex, and ... | Q2JMP3 |
Q30VM1 | TRPD_OLEA2 | Anthranilate phosphoribosyltransferase | Oleidesulfovibrio | MHTAEILETLASGGVLPPETAHMAFDRLMSGEMTPAQAGSFLMGLRSHGETPELVASAVRAALAHARLIQGLEYDRIDIVGTGGDGRNSFNCSTAAALTLAGMGYKVVKHGNRAVSSTSGSADVVEGLGLPLETAPEDVPVLLARHNFVFLFAPFYHPAFRHVMPVRRDLGIRTLFNVLGPLLNPARPTRMLLGVAKPAMLHTMADALLLTGVRRAAVVHGAGGYDELTTMGPARVVMVRDGATEEMEINPADHGFAPCTPAQLEVHDRQEALEVMRLLLAGEGPAPMLDMMAFNAGLAVYLMEDSMPISAAMARARQAV... | Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA). | Q30VM1 |
A5V9P8 | RIMM_RHIWR | Ribosome maturation factor RimM | Rhizorhabdus | MSSDRPIVLAAIIGAHGLQGEVRLKLFTEDMGAYRTLDGAGRSFTLKTIRPGPNGAVARFAEIGDRNAAEALRGTELSVPRSALPPLAPGEYYHVDLIGLPCLVDGAPVGVAAMVEDFGAGDVLEIEKPDGKRFMVPVAKAVTIEPDRLLIDPEFVE | An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosoma... | A5V9P8 |
B5QV02 | RSXC_SALEP | Rsx electron transport complex subunit C | Salmonella | MLKLFSAFRKDKIWDFDGGIHPPEMKTQSNGTPLRQVPLAPRFVIPLKQHIGAEGELCVSVGDRVLRGQALTRGRGRMLPVHAPTSGTVIAIAPHSTAHPSALAELSVIIDADGEDRWIEREGWSDYRAHSREALIERIHQYGVAGLGGAGFPTGVKLQGGGDKITTLIINAAECEPYITADDRLMQDCAAQIVEGIRILAHILQPREVLIGIEDNKPQAISMLRAVLADAHDISLRVIPTKYPSGGAKQLTQILTGKQVPHGGRSSDIGVLMQNVGTAYAVKRAVVDGEPITERVVTLTGEAVSRPGNVWARLGTPVRH... | Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Required to maintain the reduced state of SoxR. | B5QV02 |
B1VGB6 | SYP_CORU7 | Prolyl-tRNA synthetase | Corynebacterium | MITRMSSLFLHTLRDDPADAELASHKLLVRAGYIRRVAPGVYSWLPMGLRVLRKVENVVRREMDAIGGQELMFPALLPKEPYEVTRRWDEYGPELFRLKDRKEADYLLGPTHEELFTWLVKGELNSYKDFPKVLYQIQTKYRDEARPRAGILRGREFVMKDSYSFNMTDEGLDESYRLHRKAYQRIFDALGIEYVICYATSGAMGGSASEEFLAVAADGEDTFVRSTESDYAANVEAVVSIPPAEESVEDKPEAVSHESPGADTIETLVEWANEAGLTVDGAPVTAKDTLKCIVCKVTRPGEDEDGNPYAPELTGVLVPG... | Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two addit... | B1VGB6 |
Q8U7P1 | NAPA_AGRFC | Periplasmic nitrate reductase | Agrobacterium tumefaciens complex | MSSELTRRNLLKAHAAGIAAATAGIALPAAAQPVPGGVSALQIKWSKAPCRFCGTGCGVMVGVKEGKVVATHGDMQAEVNRGLNCIKGYFLSKIMYGKDRLETPLLRKKNGVYAKDGEFEPVSWDEAFDVMAQQCKRVLKEKGPTAVGMFGSGQWTIFEGYAATKLMRAGFRSNNLDPNARHCMASAAYAFMRTFGMDEPMGCYDDFEHADAFVLWGSNMAEMHPILWTRIADRRLGFDHVRVAVLSTFTHRSMDLADIPMVFKPGTDLVILNYIANHIIKTGRVNEDFVRNHTKFVRGVTDIGYGLRPDDPVEVNAANS... | Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite. | Q8U7P1 |
Q3AHU0 | SYY_SYNSC | Tyrosyl-tRNA synthetase | unclassified Synechococcus | MPDSIPSLPDWLSRGMADLFPAGDPSDADQALAARLAQAEKEGRPLRVKLGIDPTGSNIHLGHSILFRKLRAFQDGGHTAVLIIGDFTARIGDPTGKSATRVQLSKEQVAANASTYLRQLGQDQPKETALLDFETPGRLEVRYNSEWLEGMDLPAVIGLLGTGTVGQMLAKDDFSKRYGSGTPIALHEFLYPLLQGYDSVAVNADVELGGTDQKFNVAMGRDLQRHFNKGTQFGLLLPILVGLDGVQKMSKSLGNVVGLEEDPLSMYSKLEKVGDAAIDDYVTLLTDLDLASLPDNPREKQKAMALAVTASRHGIEAAQK... | Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr). | Q3AHU0 |
Q41330 | KN1_SOLLC | Homeotic protein knotted-1 | Solanum subgen. Lycopersicon | MENNNYNNHVSGENSGGQRGHFFYGGNQVLGGAAPIYGRGGDCYDPMIVKTEGGGSTSHHNHTFHYPSIIRNHHHDSTETSGGGAGAGEVIEALKAKIIAHPQCSNLLDAYMDCQKVGAPPEVAARLSAVRQEFEARQRRSLTDRDVSKDPELDQFMEAYYDMLVKYREELTRPLQEAMEFMQKIEAQLNMLGNAPVRIFNSEDKCEGVGSSEEDQDNSGGETELPEIDPRAEDRELKNHLLRKYSGYLSSLKQELSKKKKKGKLPKDARQKLITWWELHYKWPYPSESEKVALAESTGLDQKQINNWFINQRKRHWKPS... | Appears to be involved in meristem formation and in the regulation of leaf morphology. Misexpression makes the leaf more compound which is always associated with growth retardation and loss of apical dominance, resulting in dwarfed, bushy plants. Probably binds to the DNA sequence 5'-TGAC-3'. | Q41330 |
B1MZT5 | RIMM_LEUCK | Ribosome maturation factor RimM | Leuconostoc | MTKENYFKVGTIVNTHGIRGEVKIMAITDFAADRFKKGAALQIETKQGFVPVTVQSSRLHKNMWLVLFEGVTNINEIEKYKTNDIYVYGEAREALGDDEYYYDEIIDSRVVSLSGEAIGVVSEIMTTGANDVWVVKRPGQSDALIPMIDDVVKSVDVANKLITIDVLEGLLD | An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosoma... | B1MZT5 |
P74963 | RPOA_SHESP | null | Shewanella | MQGSVTEFLRPRLVDIEQISSTRAKVTLEPLERGFGHTLGNALRRILLSSMPGCAVTEVEIDGVLHEYSSIEGVQEDVLEILLNLKGLAIKLEGKDEALLTLTKSGTGPVLAGDITHDGDVEIINPEHVIRNLTGQADISMRIRVAKGRGYVPASTRIQSDDEERPIGRLLVDAAFSPVSRIAYNVESARVEQRTNLDKLVIDMETNGTLDPEEAIRRAATILAEQLDAFVDLRDVTEPEQKEEKPEFDPILLRPVDDLELTVRSANCLKAEAIHYIGDLVQRTEVELLKTPNLGKKSLTEIKDVLASRGLSLGMRLENW... | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | P74963 |
Q5E4Y6 | NORM_ALIF1 | Na(+)/drug antiporter | Aliivibrio | MHRYQKEIVRLIKLSTPVLIASVAQTGMGFVDTVMAGGVSATDMAAVAIAASVWLPSVLFGVGLLMALVPVVAQLNGSGKSKKVPFEIHQGVYLALLTSIPIMLVLYNAGFIIAAMDVEPELYEKTQGYLHAVLWAAPAFLLFQTLRSFCEGLSLTTPAMIIGFIGLAANVPLNWMFVYGELGAPALGGVGCGVATAIVYWLMFLTMTLYTFIAPKLRRVNLYENWNKPQRKEIYRLFKLGLPVALSIFFEVTLFAAVALLVSPLGSTVVAAHQVAINFSSLIFMIPMSIAVAVSIRVGHKLGEKDLDGAKVASYCGLAF... | Multidrug efflux pump that functions as a Na(+)/drug antiporter. | Q5E4Y6 |
Q9H2E6 | SEM6A_HUMAN | Semaphorin-6A-1 | Homo | MRSEALLLYFTLLHFAGAGFPEDSEPISISHGNYTKQYPVFVGHKPGRNTTQRHRLDIQMIMIMNGTLYIAARDHIYTVDIDTSHTEEIYCSKKLTWKSRQADVDTCRMKGKHKDECHNFIKVLLKKNDDALFVCGTNAFNPSCRNYKMDTLEPFGDEFSGMARCPYDAKHANVALFADGKLYSATVTDFLAIDAVIYRSLGESPTLRTVKHDSKWLKEPYFVQAVDYGDYIYFFFREIAVEYNTMGKVVFPRVAQVCKNDMGGSQRVLEKQWTSFLKARLNCSVPGDSHFYFNILQAVTDVIRINGRDVVLATFSTPYN... | (Microbial infection) Acts as a receptor for P.sordellii toxin TcsL in the in the vascular endothelium. | Q9H2E6 |
P26944 | MOAC_AZOBR | Molybdenum cofactor biosynthesis protein C | Azospirillum | MTDQPLAGFTHFDAEGRAVMVDVSGKADTERSATARGSVLMQPETLALILQGGVKKGDVLSVARLAGIMGAKRTPDLIPLCHPLMLTSVKVD | Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP). | P26944 |
Q7N8M2 | METN_PHOLL | Methionine import ATP-binding protein MetN | Photorhabdus | MIKLFHINKIFQQGARSINALSDISLHVPQGQIYGVIGSSGAGKSTLIRCVNMLERPTSGQVLVNGQDLTILSDSDLTRARRRIGMIFQHFNLLSSRTVFGNIALPLELDNIPKAEIKKRVDELLELVGLTDKHDAYPANLSGGQKQRVAIARALANSPKVLLCDEATSALDPATTRSILELLKDINRRLGLTILLITHEMDVVKRICDQVAVISGGQLIEQDIVSEVFSHPKTPIAQAFIQSTLHLDIPEDYVQKMQSHPAPNLSPLLKLEFTGQSVDAPLISMAVRRFNIDMNILSSQIDYAGGVKFGVMLAELHGEN... | Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. | Q7N8M2 |
Q72J71 | VATF_THET2 | V-ATPase subunit F | Thermus | MAVIADPETAQGFRLAGLEGYGASSAEEAQSLLETLVERGGYALVAVDEALLSDPERAVERLMRGRDLPVLLPIAGLKEAFQGHDVEGYMRELVRKTIGFDIKL | Produces ATP from ADP in the presence of a proton gradient across the membrane. | Q72J71 |
Q8NP86 | LEXA_CORGL | LexA repressor | Corynebacterium | MPNGKPDPASLSDRQRRILEVIRDAVVLRGYPPSIREIGDAAGLQSTSSVAYQLKELEKKGFLRRDPNKPRAVDVRHLPETESRSSKAATQAKSKAPQAGVHDPELAGQTSFVPVVGKIAAGSPITAEQNIEEYYPLPAEIVGDGDLFMLQVVGESMRDAGILTGDWVVVRSQPVAEQGEFVAAMIDGEATVKEFHKDSSGIWLLPHNDTFAPIPAENAEIMGKVVSVMRKL | Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair... | Q8NP86 |
B0S9A0 | RL21_LEPBA | 50S ribosomal protein L21 | Leptospira | MFAIIELGAKQFKVSPDQVFVAEKTGNTVGSTVETKVLLLSDNNKVNIGSPALSGAKVTLKVLEDCKGEKIHGFKYKKRKNYKKSWGHRQQLQKLQVVSISG | This protein binds to 23S rRNA in the presence of protein L20. | B0S9A0 |
Q46DV8 | KPTA_METBF | Probable RNA 2'-phosphotransferase | Methanosarcina | MIRKCTEHGYFRGGSCLQCKRPGRYLLDDNKEEKLGRFVSGTLRHFPESAGVTMDRFGWVNINDFCDVMRKRYSWMRKEYLYALVESDEKGRYEIRNSRIRARYGHSVNIDLDYRESDSPYLYYGASPEEVDVLLENGIFPIKQRYVHLSTSYEKAVEVALIHTENPVILQIDAFKAQEDGISLKLATDDIVLAERIPPEYLFVVEE | Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase. | Q46DV8 |
O26244 | MFNB_METTH | 4-(hydroxymethyl)-2-furancarboxaldehyde-phosphate synthase | Methanothermobacter | MLLLISPINTEEALEAIEGGADIVDVKNPAEGSLGANFPWVIRRVREMTPEDMLVSATLGDVPYKPGTVSLAAMGALVSGADYIKVGLYGTRNYDEAVDVMKNVVRAVKDQSDAIVVAAGYADAHRVGAVEPMEIPRVAADSGADLAMLDTAVKDGKTLFDFMDMEKLESFVSAARDHGLKSALAGSVGREHLKPLHEIGCDVVGIRGAACVGGDRNTGRIHRDAVRELKELLDSF | Catalyzes the formation of 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P). | O26244 |
Q9LMZ9 | NRT22_ARATH | null | Arabidopsis | MGSTDEPGSSMHGVTGREQSYAFSVDGSEPTNTKKKYNLPVDAEDKATVFKLFSFAKPHMRTFHLSWISFSTCFVSTFAAAPLIPIIRENLNLTKHDIGNAGVASVSGSIFSRLVMGAVCDLLGPRYGCAFLVMLSAPTVFSMSFVSDAAGFITVRFMIGFCLATFVSCQYWMSTMFNSQIIGLVNGTAAGWGNMGGGITQLLMPIVYEIIRRCGSTAFTAWRIAFFVPGWLHIIMGILVLTLGQDLPGGNRAAMEKAGEVAKDKFGKILWYAVTNYRTWIFVLLYGYSMGVELSTDNVIAEYFFDRFHLKLHTAGIIAA... | Involved in high-affinity nitrate transport. | Q9LMZ9 |
A9MKQ8 | TDH_SALAR | L-threonine 3-dehydrogenase | Salmonella | MKALSKLKAEEGIWMTDVPEPEVGHNDLLIKIRKTAICGTDVHIYNWDEWSQKTIPVPMVVGHEYVGEVVGIGQEVKGFNIGDRVSGEGHITCGHCRNCRGGRTHLCRNTTGVGVNRPGCFAEYLVIPAFNAFKIPDNISDDLASIFDPFGNAVHTALSFDLVGEDVLVSGAGPIGVMAAAVAKHVGARHVVITDVNEYRLELARKMGVTRAVNVAKESLTDVMAELGMTEGFDVGLEMSGAPPAFRTMLDTMNHGGRIAMLGIPPADMSIDWTKVIFKGLFIKGIYGREMFETWYKMAALIQSGLDLSPIITHRFSIDD... | Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate. | A9MKQ8 |
A0A2Z5WA18 | ISPH_BOTBR | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, chloroplastic | Botryococcus | MQVLPQTRVQGVPSGRNLSCSKAVGGTPLRALTRDVVRPARSVNVHVVADGESADDVLLRSSSVAVAEKPKVSGRAFRRSLKDTGRYVAKPINDKDSLDLMEEHGVGYSSVGLVAQMRANNNEWRFKDIRVKLASAYGYCWGVERAVQMAYEAKKKYPDRQIHLTNEIIHNPTVNERMTEMDINIIEQKENGSKDFSKVSRQDVVILPAFGASVQELSLLKDLEVQIVDTTCPWVSKVWTAVDNQARKAHTSVIHGKYSHEETIATASFAETYLIVRDIEEANYVCNYILNGGNKEEFLTKFKNAISKGFDPDRDLARVG... | Enzyme of the plastid non-mevalonate pathway for isoprenoid biosynthesis that converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). | A0A2Z5WA18 |
Q2JW78 | DNAJ_SYNJA | Chaperone protein DnaJ | unclassified Synechococcus | MARDYYEILGVSRDSSKEEIKRAYRRLARKYHPDVNKEPGAEDRFKEINRAYEVLSDDELRARYDRFGEAGLSGAAAAASGFQDFAGIGGFADLFESFFTNFAGGGVGYSRSRQGPVRGDDLRFDLKLEFLEAIFGGEKQIRISHLEVCPVCGGSGAKPGTDVKVCPTCGGAGQVRRATRTPFGNFTQVSICPTCGGAGRVLEEPCYNCNGEGLAQTTKKLRINIPAGVDSGTRLRVSGEGDAGRRGGPPGDLYVYLFVEPDPDFQRDGLTIFSQVRVSYLQAILGAKVLVPTVDSKAGLEEEAELTIPAGSQPGTVLTL... | Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bou... | Q2JW78 |
O94718 | IPI1_SCHPO | Pre-rRNA-processing protein ipi1 | Schizosaccharomyces | MGKSKKAKAKRADFNKQKLKVGKSKNAPNNFTDTSFRTKTLVLPTQAALEKEDFNTTAKDQAYFAHLLGMLKHHNANQRQETLEKLTQYVLSHTSILTTSTALLLKLTSPLILDESSSVRDCLYRFLEKFIYIMGPELLEPNIGMIFLYTHSGMTHITPSIRNDSTKFLSLLINACKDRLSSSAISLQWKKTLECFTNLLGWNSESASVKRTTSFSKKSSANMIRHLTVCNDFLQLGLNPKLQAKNQQSSVHLKYPYLQQCIVIHPKYEAFRSPCSFAYLSLFNPNKHDLVDNPTFRWQTIYPLIPGIIEFIRNSWSDAC... | Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA. | O94718 |
A3NC06 | RIMM_BURP6 | Ribosome maturation factor RimM | pseudomallei group | MAGHDSGNAKRGRSPSFGVFVRKPVERTSAKGTSDGAVDSQAIRIDAAQSWPDDAVEVGAVVDAYGLKGWVKLAAHAGAGRGGDALLKARDWWLQKGAERKFARVTQAKLHGDTVVAHPDGSVDRDTALALRGARVFVRRGDFPALAADEFYWVDLIGLDVVNEAGVALGKIADMIDNGVHSIMRVEYPATGKDGRPKTGERLIPFVGVYVKAVEQAAGRVVVDWEADY | An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosoma... | A3NC06 |
O32138 | PUCR_BACSU | Purine catabolism regulatory protein | Bacillus | MNILDVMKIPAFENANLIAGKAGGEREVQHVNMMDAPDIVDFLHKNELLVTTAYHLKDHPHQLSELIRQMAKRGCAGLGIKTKRYLEDIPKEIIELADSYAFPIIELPEHIRLGDIVNATLSHILDMRSNELQQAIYAHKKFTNHIMSGKGLQSLLKKVSDILQLPVLLLDQHAKMLSASHQISVETEKLKGTLNTVSGPFFTCFSTISDQKTYSVLPIYNHEKNCGYLLIPDMVQAGDKGLILTIEQAANVISFELLKENALKQFSRRARNEFFNNFIERTFSSDDEIKNRAKEFKLRWDQKYMCIAGKLDRNDESISF... | Activates the expression of pucFG, pucH, pucI, pucJKLM and guaD, while it represses pucABCDE and its own expression. | O32138 |
B0JHC1 | DDL_MICAN | D-alanylalanine synthetase | Microcystis | MDKIKVGLLFGGRSGEHEVSINSARSILQAFNYPENLDKYAVIPFYIDKNGCWHSAATARQILTSGQPLAIESNIKVNIWQFPPEVREMEVWFPILHGPNGEDGTLQGLLTLMRVAFVGSGVLGSCLGMDKIAMKTAFAAAGLPQVKYKAITRSQVWSNPCVFPQLCDQIAEEIGYPCFIKPANLGSSVGISKARNRQELEAALDSAASYDRRIIVEAGVTAREIECAVLGNDNPQASLVGEITFDSDFYDYETKYTDGRSSMVIPANIPDKIANQVREMAVEAFKAVDAAGLSRVDFFYVENTGEVLINEINTLPGFTN... | Cell wall formation. | B0JHC1 |
C0MCA9 | RS10_STRS7 | 30S ribosomal protein S10 | Streptococcus | MANKKIRIRLKAYEHRTLDTAAEKIVETATRTGATVAGPVPLPTERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL | Involved in the binding of tRNA to the ribosomes. | C0MCA9 |
A5CWZ3 | LEU1_VESOH | Alpha-isopropylmalate synthase | Candidatus Vesicomyosocius | MTNKLIIFDTTLRDGEQSPGASMTKDEKIRIAKVLEKMKVDVIEAGFAIASEGDFEAVQAVANIVQNSVICSLARALDKDIDRAGEALKGANASRIHTFIATSNIHMKMKLQMTPDQVVGQAVRAVKRANRYTDNIEFSPEDAGRSDEDFLCYIIEAVIKAGATTINIPDTVGYNIPHQFGATIKSLIERIPNSDKAIFSAHCHNDLGLAVANSLSAVLNGARQVECTINGLGERAGNTSLEELVMAVRTRQDIFDCDTNIDTMHILSASRLASSVTGFIIQPNKAIVGANAFAHEAGIHQDGVLKHRETYEIMRAEDVG... | Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate). | A5CWZ3 |
G2K046 | DNAK_LISM4 | Heat shock protein 70 | Listeria | MSKIIGIDLGTTNSAVAVLEGGEAKIIPNPEGARTTPSVVGFKNGERQVGEVAKRAAITNPNTISSIKRHMGTNYKETIEGKDYSPQEISAIILQYLKSYAEDYLGETVDKAVITVPAYFNDAQRQATKDAGKIAGLEVERIINEPTAAALAYGMDKTETDQTILVFDLGGGTFDVSILELGDGVFEVHSTAGDNELGGDDFDKKIIDYLVAEFKKDNGIDLSQDKMALQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEVTLTRAKFDELTHDLVERTIAPTRQALKDANLSASDIDQVILVGGSTRIPAVQ... | Acts as a chaperone. | G2K046 |
Q1LY10 | FSD1_DANRE | Fibronectin type III and SPRY domain-containing protein 1 | Danio | MDDQKESLRKIITTLALKNEEIQNFICSLKQSLENLEANSNRVQEDLESEFSSLHSVLDDLKEGMVTRIKQERASRTYELQSQLGACTKALESSEELLEFANQTLCSSENDSFTQAAKDIKDSVTMAPAFRLSLKAKASDSMNHMMVDFTHERNLLQSITFLPVPATPEIHVADCQVFDNTVTVVWTLPEPDSKIDHYILEHRKTNHEGPPRAREDYPWMVVEGIKETEYTLTGVRFDTRYMTFRVKACNKAVAGEFSEPVTLETHAFVFKLDASSSHQNLKVEDLSVEWDSSGGKVAVQDIRKEKNRTNSPMHSPARTA... | May be involved in microtubule organization and stabilization. | Q1LY10 |
Q884D4 | MACB1_PSESM | Macrolide export ATP-binding/permease protein MacB 1 | Pseudomonas | MHTPLIDLRGIRKSYGGGDSPRVNVLRGIDLSIHAGEFVAIVGASGSGKSTLMNILGCLDRPTSGEYLFAGENVAELGGDELAWLRREAFGFVFQGYHLIPSGSAQENVEMPAIYAGTPAAERHARAAALLDRLGLASRTGNRPHQLSGGQQQRVSIARALMNGGHIILADEPTGALDSHSGAEVMTLLDELASQGHVVILITHDREVAARANRVIEISDGLVISDTARDLSTPRSANPAALQAVDLRKRLSEGSGSHGAWKGELLDAIQAAWRVMWVNRFRTALTLLGIVIGVASVVVMLAVGEGSKRQVMAQMSSFGS... | Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | Q884D4 |
Q9TW28 | MYOM_DICDI | RhoGEF domain-containing protein myoM | Dictyostelium | MKHLEGDIVWVPHTVNGYCRGKIIGYNEKNQVTVRLLELNEEIKINEQLIQNYNQSDDKDFSDMVEIQDLSEAIILNNLGLRYKSDQIYTYIGNVLISINPYKEIKDIYSLNILNKYKDINTIKSNPPHIYAVALRAYQSMVSEKKNQSIIISGESGSGKTEASKTILQYLINTSNSNSNNNTNINNNNNSIEKDILNSNPILEAFGNSRTTKNHNSSRFGKFLKIEFRSSDMKIDGASIETYLLEKSRISHRPDVNNLSYHIFYYLVMGASKEERERLGLDNDPSKYRYLDASTSVIESFKKQSNGGSGGGSGNNDLSE... | Myosins are actin-based motor molecules with ATPase activity. Involved in macropinocytosis and remodeling of actin cytoskeleton. | Q9TW28 |
Q4KEN7 | AZOR4_PSEF5 | FMN-dependent NADH-azoreductase 4 | Pseudomonas | MNNLLLINASPRGQGSHGNQLALELVSSLRQRYPHLELVERDLGANPLPPLGMDYAHALTTPTPFDAPLFEVSEGLIGELERSDALLIATPMHNFTLPAALKLWIDYVLRIHRTFSSGPEGKVGLLKDRPVHVLVSSGGFHQGERARQPDFLTPYLRQVLNTLGLFDLQFTYLQGLVFGDEAVRATLDEARSALSLQPLFNPLVCA | Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines. | Q4KEN7 |
Q1C4I9 | DXS_YERPA | 1-deoxyxylulose-5-phosphate synthase | Yersinia | MSLDIAKYPTLALAENPEELRMLPKESLPKLCDELRQYLLTCVSRSSGHFASGLGVVELTVALHYVYNTPFDHLIWDVGHQAYPHKILTGRRDRISTIRQKDGLHPFPWRGESEYDVLSVGHSSTSISAGLGMAVAAEREGKGRRTVCVIGDGAITAGMAFEAMSHAGDIHSDMLVILNDNGMSISENVGGLNNHLAQLLSGKLYASLREGGKKAFSALPPIKDLLKRTEEHLKGMVVPSTLFEELGFNYIGPVDGHDVHTLTQTLKNMRDLKSPQLLHIMTKKGKGYAPAEKDPIGWHAVPKFDPASGTLPKSQSSLPT... | Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP). | Q1C4I9 |
Q64XV2 | GLAB_BACFR | Exo-alpha-galactosidase B | Bacteroides | MKTILLFALSLLLSLSVSDVCAQERVYDISQFGLKANSKKNASPVVRKAIAKIKAECRDGEKVILRFPAGRYNFHEAGSTVREYYISNHDQDNPKKVGIALEDMKNLTIDGQGSEFVFYGRMIPVSLLRSENCVLKNFSIDFEQPHIAQVQVVENDPEKGITFEPAPWVDYRISKDSVFEGLGEGWVMRYSWGIAFDGKTKHVVYNTSDIGCPTKGAFEVAPRRICSPKWKDARLVPGTVVAMRGWGRPTPGIFMSHDVNTSLLDVKVHYAEGMGLLAQLCEDITLDGFGVCLKGNNDPRYFTTQADATHFSGCKGKIVS... | Alpha-galactosidase. Removes both branched alpha-1,3-linked galactose residues of blood group B antigens and linear alpha-1,3-linked galactose structures. | Q64XV2 |
Q7YMV6 | MATK_CLELI | Intron maturase | Clematis | MEELQGYLKIDRSRERDFLYPLLFQEYIYALAHDHGLNKSILYEPMENLGYDKKYSLIIVKRLITRMYQQKHLIIFTNDSNPNFFFGHNKNLDSQMISEGVAVIVELPFSLRLVSSPESKEIDKSMTTLRSIHSIFPFLEDKLLHLNHVLDILIPYPIHLELLVQTLRSWIQDAPFLHLLRFFLYKYHNWNSLITQKTKMILFFSKENQRFFLFLYNFHVYESESIFVFLRKQSYHLRSTSSRAFLDRTHFYRKIEHFLVDFRNDFHTILWLFKDPFIQYFRFQGKSILSSKGTPLLMKKWKYYLVNLWECHFYFWSQPD... | Usually encoded in the trnK tRNA gene intron. Probably assists in splicing its own and other chloroplast group II introns. | Q7YMV6 |
A4VR98 | IDI2_PSEU5 | Type 2 isopentenyl diphosphate isomerase | Pseudomonas | MSKQSLVSRKNDHLDIVLDPTRAIAATGTGFGAFRFEHCALPELHLDQIDLQTALFGRRLRAPLLISSMTGGAARSAAINAHLAEAAQQLGIAMAVGSQRVALETAGDQGLTGQLRQLAPDILLLANFGAAQLVRGYGVDEARRAVEMIEGDALIVHLNPLQEAVQTGGDRDWRGVLQAIEALAARLPVPVVIKEVGAGISAAVARRLVDAGVAAIDVAGAGGTSWAAVEAARAADASQQAIAEAFADWGIPTAQALLAVRDACPNTPLIASGGIRDGVEAAKAICLGADLVGQAAGVLQAAMHSSEAVVSHFEVLIEQL... | Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | A4VR98 |
P36249 | RL10_LIBAS | 50S ribosomal protein L10 | Liberibacter | MNRQGKSVEISELSKIFSSSGSIVVAHYKGISVAQIKDLRKKMREAGGGVKVAKNRLVKIAIRDTSIRGISDLFVGQSLIVYSDSPVIAPKISVSFSNDNNEFRVLGGVVEKGVLNQDSIKQIASLPDLEGIRAGIISAIQSNATRLVRLLGTPQTQVVRAISAFVDKNQQG | Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. | P36249 |
B2Y1V2 | RR4_WELMI | 30S ribosomal protein S4, chloroplastic | Welwitschia | MSRYLGPRFKIIRRLKTLPGLTSKRPKYKKRVRRRFSRPWWKKSQHLICLQEKQKIRFHYGLTERQLRQYINIAKRAQGSTGQVLLQLLEMRLDNIIFQLGIARTIPAARQIVNHRHVLVNGRVVDIPSYRCKPQDVLTIKTKNPEELRTIINKNRSKFRRKVPYHLTLDLAQNKGIVNKIIDRKDIQLKIQEMLVIEYYC | With S5 and S12 plays an important role in translational accuracy. | B2Y1V2 |
A5UMJ5 | SURE_METS3 | Nucleoside 5'-monophosphate phosphohydrolase | Methanobrevibacter | MKALISNDDGVNATGILAAKNAIEDLCEVCVVAPETQQSGIGHAITLYDPLRINPTTLRDKSQAYGVTGTPTDAVTFGLFEIMGEKPDIMISGINTGFNIGKAELTTSGTIGAALEAASFGIPSIAISQEVTRDYIKFENGTVDIDFSFAGKMLRKLVKIVFKKGLPDGIDLLNVNIPENPVDEEFEVAKLGNRMYTPIIQRRLDPRGKPYYWIGGDPYNSDCEGTDGHCLKKLNKATITPLTIDLTGEMDLIKEWLK | Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates. | A5UMJ5 |
A8FW35 | RL25_SHESH | 50S ribosomal protein L25 | Shewanella | MSYTIAAEIRTEIGKGSSRRLRHANKVPAVIYGAGKEPISIKFDHKDIINIQENADFYSSDLTITVDGKDVKVRVQAMQRHAFKGLIEHIDFKFA | This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. | A8FW35 |
Q3SJP7 | NUOK_THIDA | NDH-1 subunit K | Thiobacillus | MISLSHFLVLGGVLFAIAVLGIFLNRKNVIVLLMAIELMLLAVNMNFIAFSHYLGDVHGQVFVFFILTVAAAESAIGLAILVLLFRNLRTINVDDLDQLKG | NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are t... | Q3SJP7 |
Q8CX76 | TAL_OCEIH | Probable transaldolase | Oceanobacillus | MKFFIDTANIDDIRAANSLGILAGVTTNPSLVAKEGVSFHDRLREITKEVSGSVSAEVISEDAEGMIEEGKELAAIAPNITVKVPMTLEGLKAVKVFSELNIKTNVTLIFNANQALLAARAGATYVSPFLGRLDDIGQDGMTLISAIAEIFDRHSVSTEIIAASIRHPLHVTDAALNGAHIATIPYKVLEQLVKHPLTDQGIQKFLDDWNSQK | Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. | Q8CX76 |
P32845 | NULLO_DROME | Protein nullo | Sophophora | MGSTHSAEKVKSVEDSTSPANPGIFCTPLPGFISNIQRLVLRKLSISARKQKRLNKRSKHLLRPMPRCSSFGSCGTLLTPTKKSASNIADRRYAQWKCSFEHLAQKQPRLHDISEAMTGQTTPRGFPSHTDPKRCLMVMDSSSPESPLYDMVGGQKVRRRLSLRSHALVRRPSARQKAEQAKLDAQFQRDLRDLEDYYGGFHFAQRRERLVKV | Actin-myosin network stability during cellularization. Might be involved in increasing actin-actin interactions or membrane-to-cytoskeleton attachments. nullo together with Sry-a and bnk may provide auxiliary functions, by acting both to stabilize a large and dynamic microfilament structure and regulate its functions. | P32845 |
B6JI86 | THIC_AFIC5 | Thiamine biosynthesis protein ThiC | Afipia | MNIRSNPDTTLPAVTTGPLPSSRKIFSTPEAAPDLRVPLREIILTEGAGEPNLPVYDTSGPYTDPAVVIDVNAGLPRTRMAWVKERGGIEEYEGREIKPEDNGNVGASHAAAAFKAHHKPVRGVGDAPITQLEFARAGIITKEMIYVAERENIGRKQQLERAEAALKDGESFGADIPAFITPEFVRSEIARGRAIIPCNINHAELEPMIIGRNFLTKINANIGNSAVTSSVEEEVDKMVWAIRWGADTVMDLSTGRNIHTTREWILRNAPIPIGTVPIYQALEKCEGDPVKLTWELYRDTLVEQCEQGVDYFTIHAGVRL... | Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | B6JI86 |
Q8N392 | RHG18_HUMAN | Rho-type GTPase-activating protein 18 | Homo | MSWLSSSQGVVLTAYHPSGKDQTVGNSHAKAGEEATSSRRYGQYTMNQESTTIKVMEKPPFDRSISQDSLDELSMEDYWIELENIKKSSENSQEDQEVVVVKEPDEGELEEEWLKEAGLSNLFGESAGDPQESIVFLSTLTRTQAAAVQKRVETVSQTLRKKNKQYQIPDVRDIFAQQRESKETAPGGTESQSLRTNENKYQGRDDEASNLVGEEKLIPPEETPAPETDINLEVSFAEQALNQKESSKEKIQKSKGDDATLPSFRLPKDKTGTTRIGDLAPQDMKKVCHLALIELTALYDVLGIELKQQKAVKIKTKDSG... | Rho GTPase activating protein that suppresses F-actin polymerization by inhibiting Rho. Rho GTPase activating proteins act by converting Rho-type GTPases to an inactive GDP-bound state . Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation. Acts downstream of YAP1 a... | Q8N392 |
O88426 | NDK6_RAT | nm23-R6 | Rattus | QLTLALIKPDAVAHPLILEAVHQQILSNKFLIVRMRELLWKPEDCRRFYREHEGRFFYQRLVEFMTSGPIRAYILAHKDAIQLWRTLMGPTRVFRARHIAPDSIRGSLGLTDTRNTTHGSDSVVSASREIAAFFPDFSEQRWYEEEEPQLRCGPVHYSPEEGIHCAAETGGPKPA | Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | O88426 |
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