accession stringlengths 6 10 | name stringlengths 6 11 | Full Name stringlengths 1 147 ⌀ | taxon stringlengths 3 46 ⌀ | sequence stringlengths 16 2.75k | function stringlengths 6 5.51k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
Q7XR46 | PAO4_ORYSJ | Polyamine oxidase 4 | Oryza sativa | MDPNSLKTGGLLLPTIERQCASPPSVIVIGGGISGVAAARALSNASFEVTVLESRDRVGGRVHTDYSFGCPIDMGASWLHGVCNENSLAPLIGYLGLKLYRTSGDNSVLYDHDLESYALFDKAGHQVSKETVAKVEETFERILDETVKVRDEQEHDMPLLQAISLVLERHPHLKLQGIDDQVLQWCVCRLEAWFAADADEISLKNWDQEHVLTGGHGLMVNGYYPIIQALAQGLDIRLNQRVTKIARQFNGVTVTTEDGTSYSADACIITVPLGVLKANIIKFEPELPSWKSSAIADLGVGIENKIAMHFDTVFWPNVEV... | Flavoenzyme involved in polyamine back-conversion . Catalyzes the oxidation of the secondary amino group of polyamines, such as spermine . Substrate preference is spermine > thermospermine > norspermine . No activity detected when putrescine, spermidine or N(1)-acetylspermidine are used as substrates . Plays an importa... | Q7XR46 |
Q65US7 | THIE_MANSM | Thiamine-phosphate pyrophosphorylase | Basfia | MNKIKSMLSVYFIAGSQDCRHLPGEPTENLLTILQRALEAGITCFQFREKGEQSLACDLQLKRRLALKCLQLCRQFQVPFIVNDDVELALSIQADGIHVGQKDTAVETILRNTRNKPIIGLSINTLAQALANKDRQDIDYFGVGPIFPTNSKADHSPLVGMNFIRQIRQLGIDKPCVAIGGIKEESAAILRRLGADGVAVISAISHSVNIANTVKTLAQK | Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). | Q65US7 |
Q03EB7 | RL4_PEDPA | 50S ribosomal protein L4 | Pediococcus | MANVSLFKQDGTKNGDVELNADIFGIEPNNDVVFEAVVMQRASMRQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGIVFGPTPRSYAYSIPKKMRRLALKSVLSQKVLDESLVVVDEFKFETPKTKDFAQSLGNLNVDKKALLVLEEDNESAVLAARNLSNVKIVEPEGINVLDIMNSDKLVITQKALSQVEEALA | Forms part of the polypeptide exit tunnel. | Q03EB7 |
Q8C042 | ENO4_MOUSE | 2-phospho-D-glycerate hydro-lyase | Mus | MGDEDGGRRGGITRDLQKLKQQAMAYYQENDVPRKLEDLLNSTFYLQPADVYGHLKANYFSKLAKPPSICKIVGKTILDGLGLPTLQVEISCTIQNFPKYICAVAIPTHFEVVENALPEALDAEDSERAQAVNTAVQWINQSITEELWGLVPSNQAEVDHRLRTFFEHKVQEDKERKELEKSQEELVPAPPPVTLPPPPPPPPPPPSKKKGQKAGRRDTLLEKPVSPPEPPEPVLHGSMAIGAVSLAVAKASATLASDPLYLTLASLKHDQEQPSTFSMPLLMGSVLSCGKSSPGKLHLMKEVICIPSPGLTAKQSVELL... | Required for sperm motility, function and male fertility. May be involved in the normal assembly of the sperm fibrous sheath and provides most of the enolase activity in sperm . | Q8C042 |
Q4JK59 | TET2_MOUSE | Protein Ayu17-449 | Mus | MEQDRTTHAEGTRLSPFLIAPPSPISHTEPLAVKLQNGSPLAERPHPEVNGDTKWQSSQSCYGISHMKGSQSSHESPHEDRGYSRCLQNGGIKRTVSEPSLSGLHPNKILKLDQKAKGESNIFEESQERNHGKSSRQPNVSGLSDNGEPVTSTTQESSGADAFPTRNYNGVEIQVLNEQEGEKGRSVTLLKNKIVLMPNGATVSAHSEENTRGELLEKTQCYPDCVSIAVQSTASHVNTPSSQAAIELSHEIPQPSLTSAQINFSQTSSLQLPPEPAAMVTKACDADNASKPAIVPGTCPFQKAEHQQKSALDIGPSRAE... | Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in active DNA demethylation. Has a preference for 5-hydroxymethylcytosine in CpG motifs. Also mediates subsequent conversion of 5hmC into 5-formylcytosine (5fC), and con... | Q4JK59 |
Q5HQV2 | TPIS_STAEQ | Triose-phosphate isomerase | Staphylococcus | MRTPIIAGNWKMNKTVQEAKDFVNELPTLPDPKEVESVICAPTIQLDALVTAVKDGKAKGLKIGAQNAYFEESGAYTGETSPVALSELGVKYVVIGHSERRDYFHETDEEVNKKAHAIFNHGMTPIICVGESDEEREAGKANKIVGNQVKKAVEGLSDDQLKEVVIAYEPIWAIGTGKSSTSEDANEMCAHVRQTLADLSSQEVADATRIQYGGSVKPNNIKEYMAQSDIDGALVGGASLKVEDFVQLLEGAK | Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). | Q5HQV2 |
P49771 | FLT3L_HUMAN | SL cytokine | Homo | MTVLAPAWSPTTYLLLLLLLSSGLSGTQDCSFQHSPISSDFAVKIRELSDYLLQDYPVTVASNLQDEELCGGLWRLVLAQRWMERLKTVAGSKMQGLLERVNTEIHFVTKCAFQPPPSCLRFVQTNISRLLQETSEQLVALKPWITRQNFSRCLELQCQPDSSTLPPPWSPRPLEATAPTAPQPPLLLLLLLPVGLLLLAAAWCLHWQRTRRRTPRPGEQVPPVPSPQDLLLVEH | Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins. | P49771 |
O05949 | DPO1_RICPR | DNA polymerase I | typhus group | MTKKNTLLLIDGYGFVFRAYYAQKSLSSAKGEPVGALYGFTSMLLKLLSDFKPQYVAIVFDSGGKNFRHKIYQNYKANRPLPPKDLIAQLPLVRDVASNFKFAILEKNGYEADDIIATFATKTVSLGEEVIIISSDKDLLQLMSKNIKIYDPIKCKYITEDNVVTKFGTTPDKLREVMALIGDRSDNIPGVPSIGPKTASSLITKFGSVENIFNSLDQISSIKQRKTLQNAREAALISWKLIGLDSNVDLDFDLNNLKWSPPNSKKLTGFLQEYGFKSLYKRVENLFDIKINDHEEIVDNKVTEAKEISNASELANFAKE... | In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | O05949 |
Q7TN16 | HHIP_MOUSE | Hedgehog-interacting protein | Mus | MLKMLSFKLLLLAVALGFFEGDAKFGERNEGSGARRRRCLNGNPPKRLKRRDRRVMSQLELLSGGEILCGGFYPRVSCCLQSDSPGLGRLENKIFSATNNSECSRLLEEIQCAPCSPHSQSLFYTPERDVLDGDLALPLLCKDYCKEFFYTCRGHIPGLLQTTADEFCFYYARKDAGLCFPDFPRKQVRGPASNYLGQMEDYEKVGGISRKHKHNCLCVQEVMSGLRQPVSAVHSGDGSHRLFILEKEGYVKILTPEGELFKEPYLDIHKLVQSGIKGGDERGLLSLAFHPNYKKNGKLYVSYTTNQERWAIGPHDHILR... | Modulates hedgehog signaling in several cell types, including brain and lung through direct interaction with members of the hedgehog family. Soluble forms inhibit Shh-induced differentiation in the fibroblast cell line C3H/10T1/2. | Q7TN16 |
Q98QU6 | ATPE_MYCPU | F-ATPase epsilon subunit | Mycoplasmopsis | MQLQLIITTPNGIFFNEKVDIVTVVTAGGHIGIQYGHQPLISTIEISELHINTEGHKDYRICSINGGLLYVEKDKANIITGAIEFKEDIDIEKARREHDYLVEILSNSKNKDSDYFRNELKLKKVINRLKISSNSTQSPKK | Produces ATP from ADP in the presence of a proton gradient across the membrane. | Q98QU6 |
B9UIY3 | NDB45_LYCMC | Non-disulfide-bridged peptide 4.5 | Lychas | MKVKFLLAVFLIVLVVTDHCHALFGLIPSLIGGLVSAFKGRRKRQMEARFEPQNRNYRKRELDLEKLFANMPDY | Mutant mucroporin-M1: can inhibit Gram-positive bacteria at low concentrations and antibiotic-resistant pathogens. Minimum inhibitory concentrations (MIC) are the following: MIC=12.5 ug/ml against E.coli AB94012, MIC=100 ug/ml against P.aeruginosa AB93066, MIC=25 ug/ml against B.thuringiensis AB92037, MIC=25 ug/ml agai... | B9UIY3 |
C5JIC2 | MTNB_BLAGS | Methylthioribulose-1-phosphate dehydratase | Blastomyces | MSAIKDERNNDHLVQSHDPEHPANLIPALCRNFYGHGWVTGTGGGASIKRDNHIFIAPSGVQKELIQPHNIFVLQYPTPKYPPSARQYIRKPLELKPSACTPLFLAAFDRGAGCCIHTHSQWAVLVTLLVEREKGLEGCFEISNIEQIKGIPKGKGKGMMGFFDTLKIPIIENTAFEEDLTSSLEEAMEKYPDTYAVLVRRHGIYVWGDDVAKAKTQCESLDYLFQLAVEMHKLGLPWVKP | Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). | C5JIC2 |
Q9LYW5 | LUL1_ARATH | RING finger protein 370 | Arabidopsis | MGNLISLIFCCGRRQRSNIPPAMETAPLELPPNRFVFAAVPPYLNPNPNYVDQYPGNCLPPPVTEPPMLPYNFNHLHHYPPNSYQLPHPLFHGGRYPILPPPTYVHQKAVTIRNDVNLKKKTLTLIPDPENPNRLLVSFTFDASMPGRITVVFFATEDAECNLRATKEDTLPPITFDFGEGLGQKFIQSSGTGIDLTAFKDSELFKEVDTDVFPLAVKAEATPAEEGKSGSTNVQITQVVYTKEKGEIKIEVVKQILWVNKRRYELLEIYGIENTVDGSDEGKECVVCLSEPRDTTVLPCRHMCMCSGCAKALRFQTNLC... | Acts as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates (in vitro). | Q9LYW5 |
Q8NH02 | O2T29_HUMAN | Olfactory receptor 2T29 | Homo | MANITRMANHTGRLDFILMGLFRQSKHPALLSVVIFVVFLKALSGNAVLILLIHCDAHLHSPMYFFISQLSLMDMAYISVTVPKMLLDQVMGVNKVSAPECGMQMFLYLTLAGSEFFLLATMAYDRYVAICHPLRYPVLMNHRVCLFLASGCWFLGSVDGFMLTPITMSFPFCRSWEIHHFFCEVPAVTILSCSDTSLYETLMYLCCVLMLLIPVTIISSSYLLILLTVHRMNSAEGRKKAFATCSSHLTVVILFYGAAVYTYMLPSSYHTPEKDMMVSVFYTILTPVLNPLIYSLRNKDVMGALKKMLTVRFVL | Odorant receptor. | Q8NH02 |
C1ESW4 | RUVB_BACC3 | Holliday junction ATP-dependent DNA helicase RuvB | Bacillus cereus group | MDERLLSGESAYEDADLEYSLRPQTLRQYIGQDKAKHNLEVFIEAAKMREETLDHVLLYGPPGLGKTTLANIIANEMGVNVRTTSGPAIERPGDLAAVLTSLQPGDVLFIDEIHRLHRSIEEVLYPAMEDFCLDIVIGKGPSARSVRLDLPPFTLVGATTRAGALSAPLRDRFGVLSRLEYYTVDQLSAIVERTGEVFEVEINSLAALEIARRARGTPRIANRLLRRVRDFAQVRGNGTVTMEITQMALELLQVDKLGLDHIDHKLLLGIIEKFRGGPVGLETVSATIGEESHTIEDVYEPYLLQIGFLQRTPRGRIVTP... | The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | C1ESW4 |
Q9YGC7 | 3S15_LATCO | Short neurotoxin NCA-02/NCA-05/UER-05 | Laticauda | MKTLLLTLVVVTMVCLDLGYTRRCFNQQSSQPKTTKSCPLGENSCYNKQWRDHRGSITERGCGCPKVKPGIKLRCCESEDCNN | Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission. | Q9YGC7 |
Q2KD50 | FMT_RHIEC | Methionyl-tRNA formyltransferase | Rhizobium | MSLSIIFMGTPEFSVPTLRLLADAGHRIVAVYTQPPRPGGRRGLDLQKSPVHQAAELLGLPVFTPVNFKDAEERERFAAFKADVAVVVAYGLLLPEAVLNGTRDGCYNGHASLLPRWRGAAPIQRAIMAGDEKTGMMVMKMDKGLDTGPVALSREVEIGPNMTAGELHDRLMQVGAKAMAEAMVKLEMNDLPLTPQPQDGVLYAAKIDKAETRIDFGRDARDVHNHIRGLAPFPGAWFELEIGGKPERVKVLGSELAEGQGTAGQLLTDDLLVGCASGAVRLTRLQKAGGKPLAAADFLRGTPLGAGTRLS | Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus. | Q2KD50 |
Q47MA5 | HMUV_THEFY | Hemin import ATP-binding protein HmuV | Thermobifida | MKRIRQTMRAVVHGSGLRRLTPPQRVTSGTVVLGARHLSKSYGARTVLDDVSLDVRTGEVLALVGPNGAGKSTLLSILTGDTPPDRGEVTVLDRPLAAWSPAELALRRAVLPQSFTVSFPFDVVDVVHMGRAPWAAVDVDVDDDRVVADAMAATEVTALAARKFPSLSGGEKARVMLARVLAQQTQIMLWDEPTAALDIRHQESVLRIARQRAAQGDAIVVVLHDLALAAAYADQVAILSQGQIAAYGPPAEVFTAKLLSDVYSYEVEIVSHPRTGVPLVLPVR | Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system. | Q47MA5 |
Q9BBS5 | ATPI_LOTJA | F-ATPase subunit IV | Lotus | MNVLLCSINTFKRLYDISAVEVGQHFYWQMGDFQVHAQVLITSWVVIAILLGSTILVVRNPQTIPNFGQNFFEYVLEFIRDVSKTQIGEEYGPWVPFIGTLFLFIFVSNWSGALLPWKIIQLPHGELAAPTNDINTTVALALLTSVAYFYAGISKKGLAYFGKYIQPTPILLPINILEDFTKPLSLSFRLFGNILADELVVVVLVSLVPLVVPIPVMFLGLFTSGIQALIFATLAAAYIGESMEGHH | Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. | Q9BBS5 |
Q9V4K2 | GR43A_DROME | Gustatory receptor for sugar taste 43a | Sophophora | MEISQPSIGIFYISKVLALAPYATVRNSKGRVEIGRSWLFTVYSATLTVVMVFLTYRGLLFDANSEIPVRMKSATSKVVTALDVSVVVMAIVSGVYCGLFSLNDTLELNDRLNKIDNTLNAYNNFRRDRWRALGMAAVSLLAISILVGLDVGTWMRIAQDMNIAQSDTELNVHWYIPFYSLYFILTGLQVNIANTAYGLGRRFGRLNRMLSSSFLAENNATSAIKPQKVSTVKNVSVNRPAMPSALHASLTKLNGETLPSEAAAKNKGLLLKSLADSHESLGKCVHLLSNSFGIAVLFILVSCLLHLVATAYFLFLELLS... | Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates. Gr43a is the main sugar receptor in larvae. Functions as a narrowly tuned fructose receptor in taste neurons but also as a fructose receptor in the brain. Necessary and sufficient to sense hemolymph fructose and promote fee... | Q9V4K2 |
P33399 | LHP1_YEAST | La ribonucleoprotein | Saccharomyces | MSEKPQQEEQEKPQSRRNSFAVIEFTPEVLDRCLKQVEFYFSEFNFPYDRFLRTTAEKNDGWVPISTIATFNRMKKYRPVDKVIEALRSSEILEVSADGENVKRRVPLDLTAARNARIEQNQRTLAVMNFPHEDVEASQIPELQENLEAFFKKLGEINQVRLRRDHRNKKFNGTVLVEFKTIPECEAFLKSYSNDDESNEILSYEGKKLSVLTKKQFDLQREASKSKNFSGRSRSFNGHKKKNLPKFPKNKKKNGKEESKEDSSAIADDDEEHKE | Molecular chaperone that binds nascent RNA polymerase III transcripts, stabilizing these RNAs against exonucleases. Required for the 3' endonucleolytic cleavage that matures tRNA precursors and for efficient folding of certain pre-tRNAs. Cooperates with GCD14 in the maturation of a subset of RNA polymerase III transcri... | P33399 |
A4FVT7 | RL15_METM5 | 50S ribosomal protein L15 | Methanococcus | MIRKSKKITKMRGSRTCGYGEAKKHRGAGHRGGRGNAGHQKHKWLSVCKFNPDYFGKYGFNRNPCLIKQLETINIGELEEYILKYKDAFQVEDGKVVVDATTIGYEKVLGKGRISTAMVVKAVEFSEGAKEKIEAAGGEFVEL | Binds to the 23S rRNA. | A4FVT7 |
Q9P121 | NTRI_HUMAN | IgLON family member 2 | Homo | MGVCGYLFLPWKCLVVVSLRLLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDNRVTRVAWLNRSTILYAGNDKWCLDPRVVLLSNTQTQYSIEIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVSPKIVEISSDISINEGNNISLTCIATGRPEPTVTWRHISPKAVGFVSEDEYLEIQGITREQSGDYECSASNDVAAPVVRRVKVTVNYPPYISEAKGTGVPVGQKGTLQCEASAVPSAEFQWYKDDKRLIEGKKGVKVENRPFLSKLIFFNVSEHDYGNYTCVASNKLGHTNASIMLFGPGAVSEVS... | Neural cell adhesion molecule. | Q9P121 |
A6V4G5 | CLPS_PSEA7 | ATP-dependent Clp protease adapter protein ClpS | Pseudomonas | MHAPSQIRLTFNQDHPEPHEHEDEGAGLAVQESKPVLQPPPLYKVVLFNDDYTPMDFVVEVLEVFFNMDREKATKIMLTVHTQGKAVCGLFTRDVAETKAMQVNQYARESQHPLLCEIEKDS | Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation. | A6V4G5 |
A0RBE8 | PHNX_BACAH | Phosphonoacetaldehyde phosphonohydrolase | Bacillus cereus group | MKIEAVIFDWAGTTVDYGCFAPLEVFMEIFYKRGVGITAEEARKPMGLLKIDHVRALTEMPRIANEWNRIFGQLPTETDIQEMYEEFEEILFAILPRYASPIHGVKEVIASLRERGIKIGSTTGYTREMMDIVAKEAALQGYKPDFLVTPDDVPAGRPYPWMCYKNAMELGVYPMNHMIKIGDTVSDMKEGRNAGMWTVGVILGSSELGLSEEEVENMDSAELREKIEVVRNRFVENGAHFTIETMQELESVMERIEKQELIIS | Involved in phosphonate degradation. | A0RBE8 |
Q0IAF3 | COAD_SYNS3 | Pantetheine-phosphate adenylyltransferase | unclassified Synechococcus | MRALYPGSFDPLTLGHLDLIERGCSLFGEVVVAVLQNPGKSPAFSLDQRLEQITQATSHLQGVTVTSFNGLTVNCAREHHAQLILRGLRAMSDFEYELQIAHTNRSLDSEFETIFLSTAAHYSFLSSSVVKEVARFGGRVEHMVPAVVAEDLKRFFNSAL | Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. | Q0IAF3 |
Q7SZ56 | TM218_DANRE | Transmembrane protein 218 | Danio | MADVVLGVGTGVFIITLIWILTLALTIILSRATGPTKLGIIPVVLLALIITLVLVFFPRAAEVPAPQRAAQIVDMFFIGRYVLLSLVSLVFLAALFMLLPLHFLEPIYAKPLRTH | May be involved in ciliary biogenesis or function. | Q7SZ56 |
A1SL79 | MURC_NOCSJ | UDP-N-acetylmuramoyl-L-alanine synthetase | Nocardioides | MRLPVPDQVLPADRLGRVHFVGIGGAGLSGIARIMLARGITVSGSDGTDSPTLTALRELGARVHLGHDAAHVHDVDTLVVSTAVREDNPEYVEAVRQGLRVLPRSAALAAVMAGRRVVAVAGTHGKTTTTSLLTVALQAAGADPTYAIGGDLAATGVNAAEGTGDLFVAEADESDGAFLHYSPYAAVVTNIEADHLDQWGTPEAYAAAFDEFADTLAPDGFLVCVADDPGAAALAERHRAAGRRVVTVSARDAGALDGVTLWSPGEHYLADALAALAAGVELGYAAADLARGLASYTGTKRRMERKGEAGGVRVYDSYAH... | Cell wall formation. | A1SL79 |
Q5LDN0 | RSMG_BACFN | 16S rRNA 7-methylguanosine methyltransferase | Bacteroides | MKLLLKYFPDLTEEQRKQFAALYELYIDWNSKINVISRKDIENLYEHHVLHSLGIARIIRFRAGSSVMDLGTGGGFPGIPLAILFPDTKFHLVDSIGKKVRVATEVANAIGLKNVTFRHARAEEEKQTFDFVVSRAVMPLADLIKIIRKNISPKQQNALPNGLICLKGGELEHEAMPFKHKTSMHNLNEDFDEEFFQTKKVVYVTI | Specifically methylates the N7 position of a guanine in 16S rRNA. | Q5LDN0 |
Q2S8Y5 | ERPA_HAHCH | Iron-sulfur cluster insertion protein ErpA | Hahella | MNVAETYEPTPIIFTDNAAAKVKSLIEDEGNDELSLRVFVTGGGCSGFQYGFSFDEAVNEDDTIVEKDGVRLVVDSLSYQYLVGAEVDFREGLEGAQFVIKNPNASTTCGCGSSFSI | Required for insertion of 4Fe-4S clusters for at least IspG. | Q2S8Y5 |
P33535 | OPRM_RAT | Opioid receptor B | Rattus | MDSSTGPGNTSDCSDPLAQASCSPAPGSWLNLSHVDGNQSDPCGLNRTGLGGNDSLCPQTGSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHF... | Receptor for endogenous opioids such as beta-endorphin and endomorphin . Receptor for natural and synthetic opioids including morphine, heroin, DAMGO, fentanyl, etorphine, buprenorphin and methadone . Also activated by enkephalin peptides, such as Met-enkephalin or Met-enkephalin-Arg-Phe, with higher affinity for Met-e... | P33535 |
Q1LSJ4 | RPIA_BAUCH | null | Candidatus Baumannia | MMHEKLKKAVGWAALEYVSSGMIIGVGTGSTTDHFIDALGTVKHKIEGVVSSSEQSTTKLKSMGILLFNLNDVDGLDIYVDGTDEINSNMQMIKGGGAALTREKVLAAAANKFICIADTSKQVDILGNFPLPIEVIPMAHAWVARELVHLTGGLPKYRQGVITDNGNIILDIYNLKILDAIALEKIINNIPGVVTVGLFANRCADIALISSDLGIEEISRSIK | Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. | Q1LSJ4 |
P09805 | KTXA_KLULA | Endochitinase | Kluyveromyces | MNIFYIFLFLLSFVQGLEHTHRRGSLVKRAVCYDTDQVPLNIFFGYNRADKTDSNKNMALNIFNVFRGFLAGEGGESFYNSNGNVYGFMWVGSMVHNRGFKDNILPIMENEVKNYGIPKTLYLEYDGGGDPMKSFGIILDTTSRDTVVKAAKLWSQGKKLNSYEGSKNYQATACYLSYAYRKPIVNDNFVGTCDYFTLESGKTPADQSGINGESLQGYNPNLDFSKLSAGQPICKTIGNPPNFKPSKNSDGSCKTYKVSSGESCSSIAVKYYPLSLNDIENYNKGNYGWKGCSSLQKDYNLCVSDGSAPRPVSNPIAECG... | The alpha subunit is a potent exochitinase. Along with the beta subunit it plays a role in the initial interaction of the toxin with sensitive cells and allow the gamma subunit (the active toxin) to gain entry into the cell. | P09805 |
B0S2B6 | RF1_FINM2 | Peptide chain release factor 1 | Finegoldia | MFENLDSVVDKFKDLEVKVADPEVIADMENWTKLMKEHADLEPVVNKYLSYKDNLKNLEEDKELLGTTGDSEMEELLKDEISTLEEQIEKDQEELKILLLPKDPNDEKNVFIEIRAGAGGDEAGLFAGELLRMYQMYSDKKHWTTEIMDIQQQGVGGIKEVVMMVKGKGAYSRLKYESGVHRVQRVPQTESSGRIHTSTATVAVLPEAEDVDVKIEQKDLRIDVFRASGNGGQCVNTTDSAVRITHIPTGLVVTCQDEKSQIKNKDKAMKVLKSRLYDLMEEEKNKDRADARKSQVGTGDRSERIRTYNFPQGRITDHRI... | Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | B0S2B6 |
Q8XHA7 | PROA_CLOPE | Glutamyl-gamma-semialdehyde dehydrogenase | Clostridium | MNNELIIKGKKAKEASYTLSFASTNEKDNGLLKISEFLIKRCDEILEENKKDLEKAIEKGTSNAMLDRLKLDEERVKSIANAVADVVKLDDPIGEVTSMFKRPNGLRIGVQRVPLGVVGIIYEARPNVTADAAALCLKTGNAVILRGGSEAINSNLKIVEIISDALKEAGLPEGSVQILEDTSRETATDFMRLNDYLDVLIPRGGAGLIKAVVNNATVPVIETGVGNCHIYIDDEADINMGVDIIVNAKTSRPAVCNAAEKLLVNEKIAEEFLPVAIKALKEKGVEIRGCEKTKAIVNDINLATEEDWGKEYLDYILGVK... | Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. | Q8XHA7 |
B8H3S9 | DHMA_CAUVN | Haloalkane dehalogenase | Caulobacter | MDVLRTPDERFEGLADWSFAPHYTEVTDADGTALRIHHVDEGPKDQRPILLMHGEPSWAYLYRKVIAELVAKGHRVVAPDLVGFGRSDKPAKRTDYTYERHVAWMSAWLEQNDLKDIVLFCQDWGGLIGLRLVAAFPERFSAVVVSNTGLPIGVGKSEGFEAWLNFSQNTPELPVGFILNGGTARDLSDAERSAYDAPFPDESYKEGARIFPALVPITPEHASVEENKAAWAVLETFDKPFVTAFSDADPITRGGEAMFLARVPGTKNVAHTTLKGGHFVQEDSPVEIAALLDGLVAGLPQA | Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons. | B8H3S9 |
A5VIC6 | KTHY_LIMRD | dTMP kinase | Limosilactobacillus | MDGKFISFEGPDGAGKTSVIQQIQLELEDQLGTEKVMYTREPGGNKISEQIRQVLFDGQNTDMDGRTEALLFAAARRQHIVSEIIPGLKAGKVILCDRFVDSSIAYQGAGRGLGEKEIWQINQFAIDGLMPALTIYLDIESEIGLKRIAEHRSNQVNRLDEEKLEFHRTVRQSYLKLYQNYPERIELIDASQPLEKVIEDVKATIHDRFSDLF | Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. | A5VIC6 |
A2BPY8 | PURA_PROMS | IMP--aspartate ligase | Prochlorococcus | MANVVVIGAQWGDEGKGKITDLLSRSADVVVRYQGGVNAGHTIVVDDKVLKLHLIPSGILYKNTSCLIGSGTVIDPKILLKEIDMLIDNGIDISGLKISSTSHVTMPYHRILDEAMEADRGSNKIGTTGRGIGPTYADKSQRNGIRIRDLLNKERLSDVIEIPLREKNGLLEKIYGIKPLKLEDIVEEYLDYGERLSKHVVDCTRTIHAASKNKKNILFEGAQGTLLDLDHGTYPFVTSSNPISGGACIGAGVGPTLIDRVIGVAKAYTTRVGEGPFPTELQGSINDQLCDRGSEFGTTTGRRRRCGWFDGVIGKYAVSV... | Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. | A2BPY8 |
Q47IZ9 | CH10_DECAR | Chaperonin-10 | Dechloromonas | MNIRPLHDRVIVKRVEAERTTASGIVIPDSAGEKPDQGEVLAVGPGKRDDNGKQIALDVKVGDRVLFGKYAGQAVKVDGQEVLVMREEDIMGVLVA | Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of ... | Q47IZ9 |
Q9XX85 | ST217_CAEEL | G-protein coupled receptor str-217 | Caenorhabditis | MLLFQKTLSRVAAPISVAANLILILLIIFKSPAQMGNYKYLLIGLSIFEMSYAVLDVVSETTVLSIKKSFVVVVPYKDRSFGQETAMDINLIYCGFFGFSMGMFVVIFAYRSFLTTGNTILRKFEGFKIISWFAYPLFYAIVWILVAWGPLASFPEMDIVVRPFLLDELNMTVDEVAYTGRLFYSTIDNSLRYSAILTGVLQWVLTASSLFLVIFFGLRCYFHYGKLVQLTDVQSIRLRQLQNQLFLALVCQATVPLILMHIPVTILYTCCVLNIVFNPFSVATTIALFPAIDPLPTIFIVKNYRVALFEFVCPSCLCWS... | Probable G-protein coupled receptor. | Q9XX85 |
A1K5Y4 | PLSX_AZOSB | Phosphate-acyl-ACP acyltransferase | Azoarcus | MSVTVAVDCMGGDHGPVVTVPAVFAFLRSHADARAIAVGREEVLAPLIAPVAKEFGERLRLQPATEVVGMDEAPATAMRNKKDSSMRVAIDLVKSGEATAAVSAGNTGALMAISRFVLKTLPGIDRPAIATVLPSRDGRTYVLDLGANVDCSPEHLLQFGIMGAMLVSAVEHIDRPTVGLLNIGEEAIKGNEVVKQAGELLRTSGLNFKGNVEGDQIYTGGVDVVVCDGFVGNVALKTSEGLAQMLATFLREEFSRNLLTKLMAIVALPALGRFKRRVDHRRYNGASLLGLRGVVVKSHGSADAFAFEQALGRAADAAAN... | Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. | A1K5Y4 |
Q31886 | RBL_BOUTR | Ribulose bisphosphate carboxylase large chain | Bouvardia | MSPQTETKASVGFKAGVKEYKLTYYTPEYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVPGEEDQFIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPIAYVKTFEGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRACYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKAQAETGEIKGHYLNATAGNCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLSHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRM... | RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site. | Q31886 |
P55001 | MFAP2_HUMAN | Microfibril-associated glycoprotein 1 | Homo | MRAAYLFLLFLPAGLLAQGQYDLDPLPPFPDHVQYTHYSDQIDNPDYYDYQEVTPRPSEEQFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPCKQCLNEVCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSCGSC | Component of the elastin-associated microfibrils. | P55001 |
P15455 | CRU1_ARATH | 12S seed storage protein CRA1 basic chain | Arabidopsis | MARVSSLLSFCLTLLILFHGYAAQQGQQGQQFPNECQLDQLNALEPSHVLKSEAGRIEVWDHHAPQLRCSGVSFARYIIESKGLYLPSFFNTAKLSFVAKGRGLMGKVIPGCAETFQDSSEFQPRFEGQGQSQRFRDMHQKVEHIRSGDTIATTPGVAQWFYNDGQEPLVIVSVFDLASHQNQLDRNPRPFYLAGNNPQGQVWLQGREQQPQKNIFNGFGPEVIAQALKIDLQTAQQLQNQDDNRGNIVRVQGPFGVIRPPLRGQRPQEEEEEEGRHGRHGNGLEETICSARCTDNLDDPSRADVYKPQLGYISTLNSYD... | Seed storage protein. | P15455 |
Q67N08 | AROC_SYMTH | 5-enolpyruvylshikimate-3-phosphate phospholyase | Symbiobacterium | MRYLTAGESHGRALVTIVEGLPAGVPVDLAAIDRDLARRQSGYGRGGRMKIEQDRVQVLSGIRHGKTLGSPVALLVENRDWLNWTEVMSPAPLEAYTDPRAAQKVRTRPRPGHADLAGALKYDHADLRNVLERASARETAARVAAGSLAKQYLAPFGIRVAGYVRSIGPVEAQPPAGLDLDGIVARAEASPVRCPDPAASARMVEEIDAAKRDGDSLGGVVEVVAAGLPPGLGSHVHWDRKLDGALGAALLSIQAAKGVEIGDGFLGARRRGSEVHDEIGWSPDRGYFRYTNRAGGLEGGMTNGMDLVVRVAFKPIATLY... | Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a s... | Q67N08 |
Q6YGZ1 | HPSE_MOUSE | Heparanase 50 kDa subunit | Mus | MLRLLLLWLWGPLGALAQGAPAGTAPTDDVVDLEFYTKRPLRSVSPSFLSITIDASLATDPRFLTFLGSPRLRALARGLSPAYLRFGGTKTDFLIFDPDKEPTSEERSYWKSQVNHDICRSEPVSAAVLRKLQVEWPFQELLLLREQYQKEFKNSTYSRSSVDMLYSFAKCSGLDLIFGLNALLRTPDLRWNSSNAQLLLDYCSSKGYNISWELGNEPNSFWKKAHILIDGLQLGEDFVELHKLLQRSAFQNAKLYGPDIGQPRGKTVKLLRSFLKAGGEVIDSLTWHHYYLNGRIATKEDFLSSDVLDTFILSVQKILK... | Endoglycosidase that cleaves heparan sulfate proteoglycans (HSPGs) into heparan sulfate side chains and core proteoglycans. Participates in extracellular matrix (ECM) degradation and remodeling. Selectively cleaves the linkage between a glucuronic acid unit and an N-sulfo glucosamine unit carrying either a 3-O-sulfo or... | Q6YGZ1 |
Q5ZXP6 | RIMO_LEGPH | Ribosome maturation factor RimO | Legionella | MNHKVGFVSLGCPKALVDSERIITQLKAQGYELVPTYQDAGVVVINTCGFIDSAVQESLDTIKEAMAENGRVIVTGCLGAKADVIKNACPDVLHISGAHAYEEVVNAVHQYLPPPADPFTQLIPPQGIKLTPRHYAYLKISEGCNQKCTFCIIPTMRGKLQSYPMAQILTEAKKLKQAGVKELLVISQDTSAYGVDTRYQQVEWQGKTVNTRFYDLCEQLGELGIWVRLHYVYPYPHVDDIVPLMRDGLILPYLDIPLQHANSRILKAMKRPASSENTLLRIASWREICPDITLRSTFIVGFPGETEEEFSELLAFLKEA... | Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12. | Q5ZXP6 |
B3QP81 | KTHY_CHLP8 | dTMP kinase | Chlorobaculum | MLITFEGIDGAGKSTQVVKLKRHLQERGREVLTLREPGGTPVAEQIRELLLESHNDITSIAELLLFSASRAELMEKIIVPALEDGCDVILDRFFDSTTAYQGYGRGLNLDMLAEINRIASHGIRPDITFYLDLTPEDALLRKFSEKSLPLAFESEELDRMENSGLEFYQRVRAGYHAILEAEPQRIIMIDALLTPQEIHRKILSALQALEVPEDGKR | Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. | B3QP81 |
C1B381 | RECA_RHOOB | Recombinase A | Rhodococcus | MAPQAHDRDKALDLALAQIDKNFGKGSVMRLGEGVRQPIAVIPTGSISLDVALGIGGLPRGRVVEIYGPESSGKTTVALHAVANAQAAGGIAAFIDAEHALDPDYAQKLGVDTDALLVSQPDTGEQALEIADMLIRSGALDILVVDSVAALVPRAEIEGEMGDSHVGLQARLMSQALRKMTGALSNSGTTAIFINQLREKIGVMFGSPETTTGGKALKFYSSVRLDVRRIETLKDGTDAVGNRTRVKVVKNKVAPPFKQAEFDILYGQGISKEGSLIDMGVEHGFIRKSGSWYTYEGDQLGQGKENARKFLLENTDIRDE... | Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage. | C1B381 |
A7Z0J4 | HSLO_BACVZ | Heat shock protein 33 homolog | Bacillus amyloliquefaciens group | MDYLIKAIAYDGKVRAYAARTTDMVNEAQRRHDTWPTASAAIGRTMTASLMLGAMLKGEDKLTVKIEGGGPIGAIVADANAKGEVRAYVSNPHVHFDLNEQGKLDVRRAVGTDGTLSVVKDLGLRDYFTGQVEIVSGELGDDFTYYLVSSEQVPSSVGVGVLVNPDNTILAAGGFIIQLLPGTDEETISTIEKQLSQIEPISKLIQKGLTPEEILEEVLGQKPDVLETMPVKFHCSCSKDRFETAILGLGKKEIQDMIEEDGKAEAVCHFCNEKYLFTKEELEELRDETTR | Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress. | A7Z0J4 |
Q03I69 | RLMH_STRTD | rRNA (pseudouridine-N3-)-methyltransferase RlmH | Streptococcus | MKVKLITVGKLKEKYLKDGIAEYIKRLGRFTKFESIELTDEKTPDNASESENKAILDKEGQRILAKVGDRDYVIALAIEGKQFPSEQFAKELEQATLRGYSDITFIIGGSLGLSPKVKKRANQLMSFGLLTFPHQLMRLVLVEQIYRAFMIQQGSPYHK | Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. | Q03I69 |
A8FST3 | SURE_SHESH | Nucleoside 5'-monophosphate phosphohydrolase | Shewanella | MIKILVSNDDGVTAPGIKALSDALSTSYQVMTVGPDRNCSGASNSLTLTNPLRINTLSNGYVSVSGTPTDCVHLAIRELYTDEPDMVVSGINAGANLGDDTLYSGTVAAAMEGRFLGLPAIAISLVGSTLTHYETAAHFACKVIAGLLKKPIAQDQILNINVPDLPIEQVKGIRVTRLGARHKAEGMIRTQDPAGRDIFWLGPPGDEQDASDGTDFHAVTNGYVSVTPLTVDLTAFEQISTMQQWIDKI | Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates. | A8FST3 |
B2UQY9 | EFTU_AKKM8 | Elongation factor Tu | Akkermansia | MAKEQFQRNKPHVNVGTIGHVDHGKTSLTAAITSVLAKKGFAEARGYDQIDAAPEERERGITISTAHVEYETENRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAASDGPMPQTREHILLARQVGVPAIVVYMNKCDLVDDPDLLELVEMEIRELLNEYEFPGDDTPIIKGSAVKALEGDAAAEDSIMELMAAVDSYIPQPERPVDQPFLMPVEDVFSISGRGTVATGRIERGVIKKMEEVEIIGIKDTQKTAVTDIEMFRKLLDEGQAGDNVGLLLRGLKKEDIERGQVIIKPGTVKPHKNFKAEVYVLTKEEGGRH... | This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. | B2UQY9 |
B8CH91 | FADB_SHEPW | 3-hydroxyacyl-CoA dehydrogenase | Shewanella | MIYQSPTIEVELLEDNIAHLCFNAQGSVNKFDRETIDSLNAALDSIKQNNSIKGLMLTSAKPAFIVGADITEFLGLFAEEDAVLLSWLEEANVVFNKLEDLPFPTISAINGFALGAGCETILATDFRVADTTARIGLPETKLGIIPGFGGTVRLPRVVGTDNALEWITSGKDQRPEAALNVGAIDALVAPEQLQSAALKMLKDAIAEKLDWQTRRAKKLAPLTLPKLEAMMSFATAKGMVFKVAGKHYPAPMAVVSVIEKAAQLDRAGALKVEHQAFLKLAKTEVAQSLIGIFLNDQLVKGKAKKAGKLAKKVNSAAVLG... | Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. | B8CH91 |
P47407 | RL14_MYCGE | 50S ribosomal protein L14 | Mycoplasma | MVSFMTRLNVADNTGAKQVGIIKVLGATYKRYAFLGDVVVVSVKDAIPNGMVKKGQVLRAVIVRTKKGQQRQDGTHLKFHDNACVLIKEDKSPRGTRIFGPVARELREKGYNKILSLAVEVV | Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome. | P47407 |
Q8GVC7 | PKZ1_PHYIN | Cleavage-associated kinase | Phytophthora | MLRLGRSAASEVSSIRNSLQLQLEQRGARPMQCAYQTQSHSNPEGAKRGRSPMSLAVMGAAALSVGLELQTDGIAQARAAMEPGTQLQRHKWQLFDQIGAGAFGVVRLGMHEESGEVAAVKIVPLENPNDQRSYPALEREIAALKLVKALGGHNSIVDLRDVYVEGRKLFLVTELARGGELFEQIVAYGSFPELKARDVAREMASALSFMHRHGLVHKDVKPENILMSARVVDHNSGVYRKSNRHESSSLVKLADFGSAGPASVNTNLEDIGTAAYLPPEVLNSGMCTSACDMWALGCVLYIMLSGSHPFDLDGMSADSV... | May regulate an early stage of the zoospore pathway. | Q8GVC7 |
A7FNI2 | RPOC_YERP3 | Transcriptase subunit beta' | Yersinia | MKDLLKFLKAQTKTEEFDAIKIALASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVIEGGMTNLERRQILTEEQYLDALEEFGDEFDAKMGAEAIQALLKNMDLEAECEILREELNETNSETKRKKLTKRIKLLEAFVQSGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSN... | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | A7FNI2 |
Q05196 | PABP5_ARATH | Polyadenylate-binding protein 5 | Arabidopsis | MAAAVASGIAPTTAMVDQVIPNQPTVAAAAPPPFPAVSQVAAVAAAAAAAEALQTHPNSSLYVGDLDPSVNESHLLDLFNQVAPVHNLRVCRDLTHRSLGYAYVNFANPEDASRAMESLNYAPIRDRPIRIMLSNRDPSTRLSGKGNVFIKNLDASIDNKALYETFSSFGTILSCKVAMDVVGRSKGYGFVQFEKEETAQAAIDKLNGMLLNDKQVFVGHFVRRQDRARSESGAVPSFTNVYVKNLPKEITDDELKKTFGKYGDISSAVVMKDQSGNSRSFGFVNFVSPEAAAVAVEKMNGISLGEDVLYVGRAQKKSDR... | Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation. | Q05196 |
Q86YC2 | PALB2_HUMAN | Partner and localizer of BRCA2 | Homo | MDEPPGKPLSCEEKEKLKEKLAFLKREYSKTLARLQRAQRAEKIKHSIKKTVEEQDCLSQQDLSPQLKHSEPKNKICVYDKLHIKTHLDEETGEKTSITLDVGPESFNPGDGPGGLPIQRTDDTQEHFPHRVSDPSGEQKQKLPSRRKKQQKRTFISQERDCVFGTDSLRLSGKRLKEQEEISSKNPARSPVTEIRTHLLSLKSELPDSPEPVTEINEDSVLIPPTAQPEKGVDTFLRRPNFTRATTVPLQTLSDSGSSQHLEHIPPKGSSELTTHDLKNIRFTSPVSLEAQGKKMTVSTDNLLVNKAISKSGQLPTSSN... | Plays a critical role in homologous recombination repair (HRR) through its ability to recruit BRCA2 and RAD51 to DNA breaks . Strongly stimulates the DNA strand-invasion activity of RAD51, stabilizes the nucleoprotein filament against a disruptive BRC3-BRC4 polypeptide and helps RAD51 to overcome the suppressive effect... | Q86YC2 |
Q5U901 | CBPA6_MOUSE | Carboxypeptidase A6 | Mus | MNFLGNPRSHTAAFLPVCWLLLNILKPGHCHSYDNRYAGDKVIRLIPKSEEEALALKNIYHQLKVDLWQPSSISYVSEGTITDVHISQNASRTLLAFLQETHIYYKVLIEDLQKAVENENSLQTQRNRRSLSEYNYEVYHSLEDIQSWLHHLNQTQPGLVRVFSIGRSYEGRPLFIMQLGRKSRAYKRAVWIDCGIHAREWIGPAFCQWFVREAILTYKTDPAMKKMLNHLYFYIMPVFNVDGYHFSWTHDRFWRKTRSRDSKFRCRGVDANRNWKVKWCDEGASAHPCDDTYCGPFPESEPEVKAVANFLRKHRKRIRA... | May be involved in the proteolytic inactivation of enkephalins and neurotensin in some brain areas. May convert inactive angiotensin I into the biologically active angiotensin II. Releases a C-terminal amino acid, with preference for large hydrophobic C-terminal amino acids and shows only very weak activity toward smal... | Q5U901 |
A0A140JWT3 | PTMC_PENSI | Penitrem biosynthesis cluster 1 protein C | Penicillium | MTTMLTTPLSGWSQLSLSFLTLTVGALALIVVLYISIDRFPAPRWLSKKYQLIGQKDPASTTSLECPYSYIRQIYGHYHWAPFVHKLSPTLQYDDPAKYKMVLEIMDAIHLCLMLVDDISDGSDFRKGRPAAHRIYGPSETANRAYLRVTQILNQTTSGFPHLAPWLMRDLENILEGQDLSLVWRRDGLKNFPTAPLERAAAYQRMASLKTGSLFRLLGHLVLEDRSMDDTMTLVAWYSQLQNDCKNVYSTEYAKMKGAIAEDLSNGELSYPIVLAMNAPDGHWVDLALQSPSPWNVRNALRVIRSDKVHQMCMAEMAES... | Prenyl transferase; part of the gene cluster that mediates the biosynthesis of the indole diterpenes penitrems . The geranylgeranyl diphosphate (GGPP) synthase ptmG catalyzes the first step in penitrem biosynthesis via conversion of farnesyl pyrophosphate and isopentyl pyrophosphate into geranylgeranyl pyrophosphate (G... | A0A140JWT3 |
Q4QK37 | IF2_HAEI8 | Translation initiation factor IF-2 | Haemophilus | MTEDVKADAPKKLSIQRRTKTTVSSTTTGGKSKEVQVEVRKKRTVKTDIAQQEEAKLKAQQEAEAKKIAEQKAAEEKARLEAEKAATKKEADEKSKAEKAKAETAKPAKSAVDSKAKFVDPEKEKRKAEEAELRRKAEEVARQKAEEQARRAAEEAKRYAEADDSDNESSSEDYSDYNLSSRYALEAEDEEDRRNENRGRGKNKVAKAKKGGRDDENSKNSKNERESNRKNQKDAKFGKGKNGKKGTALQQAFTKPVQVVKADVVIGETITVAELANKMSVKATEIIKVMMKMGEMVTINQVIDQETAQLVAEELGHKVI... | One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. | Q4QK37 |
P43176 | BEV1C_BETPN | Allergen Bet v I-C | Betula | MGVFNYESETTSVIPAARLFKAFILEGDTLIPKVAPQAISSVENIEGNGGPGTIKKITFPEGSPFKYVKERVDEVDHANFKYSYSMIEGGALGDTLEKICNEIKIVATPDGGSILKISNKYHTKGDQEMKAEHMKAIKEKGEALLRAVESYLLAHSDAYN | May be a general steroid carrier protein. | P43176 |
Q32NH9 | FXJ12_XENLA | Forkhead box protein J1.2 | Xenopus | MPVLSTTHRLPLSVERERNREDDSLTNLQWLQDFSILSTDLSSIANSRPPVPRVSQGPCSPPAGDTASCQAPRTGKQRVTVPTAWASLPTLSPSPVQEVDYRTNANVKPPYSYATLICMAMEASQQRKLTLSAIYNWITQNFCYYRHADPSWQNSIRHNLSLNKCFMKVPRGKDEPGKGGFWQMDPRYADMFVNGVLKRRRMPSSHLDPPRCNKTIGHHPYLPVSRPGSHHMQHISGGHRQSRRYEKPNPVLPAFRAPERQGDTLFTPEDPLQGSNFDDLDLQAALISMCWEGDLAASNLNSTLTGNSGMDMNQQDPPMQ... | Key transcription factor required for motile ciliogenesis. Activates genes essential for motile cilia formation and function. | Q32NH9 |
Q10716 | CYSP1_MAIZE | Cysteine proteinase 1 | Zea | MAHRVLLLLSLASAAAVAAAVDAEDPLIRQVVPGGDDNDLELNAESHFLSFVQRFGKSYKDADEHAYRLSVFKDNLRRARRHQLLDPSAEHGVTKFSDLTPAEFRRTYLGLRKSRRALLRELGESAHEAPVLPTDGLPDDFDWRDHGAVGPVKNQGSCGSCWSFSASGALEGAHYLATGKLEVLSEQQFVDCDHECDSSEPDSCDSGCNGGLMTTAFSYLQKAGGLESEKDYPYTGSDGKCKFDKSKIVASVQNFSVVSVDEAQISANLIKHGPLAIGINAAYMQTYIGGVSCPYICGRHLDHGVLLVGYGASGFAPIRL... | Involved in the degradation of the storage protein zein. May play a role in proteolysis during emergencies. | Q10716 |
Q329K8 | KGUA_SHIDS | GMP kinase | Shigella | MAQGTLYIVSAPSGAGKSSLIQALLKTQPLYDTQVSVSHTTRQPRPGEVHGEHYFFVNHDEFKEMISRDAFLEHAEVFDNYYGTSREAIEQVLATGVDVFLDIDWQGAQQIRQKMPHARSIFILPPSKIELDRRLRGRGQDSEEVIAKRMAQAVAEMSHYAEYDYLIVNDDFDTALTDLKTIIRAERLRMSRQKQRHDALISKLLAD | Essential for recycling GMP and indirectly, cGMP. | Q329K8 |
P49723 | RIR4_YEAST | Ribonucleotide reductase small subunit 2 | Saccharomyces | MEAHNQFLKTFQKERHDMKEAEKDEILLMENSRRFVMFPIKYHEIWAAYKKVEASFWTAEEIELAKDTEDFQKLTDDQKTYIGNLLALSISSDNLVNKYLIENFSAQLQNPEGKSFYGFQIMMENIYSEVYSMMVDAFFKDPKNIPLFKEIANLPEVKHKAAFIERWISNDDSLYAERLVAFAAKEGIFQAGNYASMFWLTDKKIMPGLAMANRNICRDRGAYTDFSCLLFAHLRTKPNPKIIEKIITEAVEIEKEYYSNSLPVEKFGMDLKSIHTYIEFVADGLLQGFGNEKYYNAVNPFEFMEDVATAGKTTFFEKKV... | Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. RNR4 is required for proper folding of RNR2 and assembly with the large subunits. | P49723 |
Q96CB9 | NSUN4_HUMAN | NOL1/NOP2/Sun domain family member 4 | Homo | MAALTLRGVRELLKRVDLATVPRRHRYKKKWAATEPKFPAVRLALQNFDMTYSVQFGDLWPSIRVSLLSEQKYGALVNNFAAWDHVSAKLEQLSAKDFVNEAISHWELQSEGGQSAAPSPASWACSPNLRCFTFDRGDISRFPPARPGSLGVMEYYLMDAASLLPVLALGLQPGDIVLDLCAAPGGKTLALLQTGCCRNLAANDLSPSRIARLQKILHSYVPEEIRDGNQVRVTSWDGRKWGELEGDTYDRVLVDVPCTTDRHSLHEEENNIFKRSRKKERQILPVLQVQLLAAGLLATKPGGHVVYSTCSLSHLQNEYV... | Involved in mitochondrial ribosome assembly. 5-methylcytosine rRNA methyltransferase that probably is involved in mitochondrial ribosome small subunit (SSU) maturation by methylation of mitochondrial 12S rRNA; the function is independent of MTERFD2/MTERF4 and assembled mitochondrial ribosome large subunit (LSU). Target... | Q96CB9 |
Q66H38 | GAR3_RAT | Protein FAM71B | Rattus | MSSECLLPYYTAHSYRSMGVFNTSMGNLQRQLYKGGEYDIFKYAPMFESDFIQISKKGEVIDVHNRVRMVTVCIASTSPVLPLPDVMLLARPAKVCEEHARRARFIKGRGYKPSKTLELTRLLPLKFVKISIHDHEKQQLRLKLATGRTFYLQLCPSSDAREDLFCYWEKLVYLLRPPVNSCISNPSIPTADTSTETKSTLVSEIHGEGDRDSKFQTSQDVSEATSAAFAGGERTQPNIAAILTTGLAKARAAGAAAGTGAAGTAGTAGAAGATGAAGATGAAGSARAAGGAGSARAAGATGSARAAGATGSARAAGATG... | May be involved in RNA biogenesis. | Q66H38 |
Q04TF0 | TPIS_LEPBJ | Triose-phosphate isomerase | Leptospira | MRKTVIAGNWKMNLSEKEALSLAHSIKEKIPAISKGRISMIFPSTLHLAGVAKILQGTEILVGAQNVYPSGLAAFTGETSPEQLKELGVKVVMIGHSERRQFLGETNSFCNEKIHFLLKNDFIVLYCVGETLMERESGKTFEVISSQIREGLKGIHSHSFSNLILAYEPVWAIGTGKVATPAQAQEVHFFIRKEIAGLFLGAKEIAESISILYGGSVKPDNIQTLLKEKDLDGGLVGGASQKIDTYAGLF | Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). | Q04TF0 |
P61695 | IF1_THET2 | Translation initiation factor IF-1 | Thermus | MAKEKDTIRTEGVVTEALPNATFRVKLDSGPEILAYISGKMRMHYIRILPGDRVVVEITPYDPTRGRIVYRK | One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-... | P61695 |
P74035 | RIMM_SYNY3 | Ribosome maturation factor RimM | unclassified Synechocystis | MAEPMTEQQKTENWLEIGTIVAAQGIQGEVRVLSASDFPARFLTKGQRWIRKTPQETPQPLTLKKGKQIPGKNLYILRFTEITDRNQAEALVNYQLLVPATDRLPLEPGEFHVTDLLGLIVYDHDNGDRLGIVTDFYSAGNDLLGITLDKNPDKEVLVPFVEAIVPTVELAEQRLEIKTIPGLLD | An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosoma... | P74035 |
B7V3I5 | HUTI_PSEA8 | Imidazolone-5-propionate hydrolase | Pseudomonas | MKRLWQHCHAATLKGGKYSIVEDAALVTDGPLIHWIGPRAELPPGDYAERIDLGGAWLTPGLIDCHTHAVFGGNRSGEFEQRLEGVSYAVIAAAGGGIASTVRATREASEEELLASARKRLEPLLRDGVTALEIKSGYGLDLASERKMLRVIRRLGERLPATVRSTCLAAHALPPEYAGRADDYIEHICSTMLPALAGEGLVDAVDAFCEHLAFSPAQVERVFIAARELGLPVKLHAEQLSSLHGSSLAARYRALSADHLEYMTEDDARAMGEAGTVAVLLPGAFYLLRETQLPPIDALRRHGVAMAIASDLNPGTSPAL... | Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway. | B7V3I5 |
Q5RE48 | AKTIP_PONAB | Fused toes protein homolog | Pongo | MNPFWSMSTSSVRKRSEGEEKTLTGDVKTSPPRTAPKKQLPSIPKNALPITKPTSPAPAAQSTNGTHASYGPFYLEYSLLAEFTLVVKQKLPGVYVQPSYRSALMWFGVIFIRHGLYQDGVFKFTVYIPDNYPDGDCPRLVFDIPVFHPLVDPTSGELDVKRAFAKWRRNHNHIWQVLMYARRVFYKIDTASPLNPEAAVLYEKDIQLFKSKVVDSVQVCTARLFDQPKIEDPYAISFSPWNPSVHDEAREKMLTQKKKPEEQHNKSVHVAGLSWVKPGSVQPFSKEEKTVAT | Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). Regulates apoptosis by enhancing phosphorylation and activation of AKT1. Increases release of TNFSF6 via the AKT1/GSK3B/... | Q5RE48 |
Q7CG87 | SURA_YERPE | Rotamase SurA | Yersinia | MKNWRTLILGLVICANTAFAAPQEVDKVAAVVDNGVVLQSDIDGLLQSVKMNAQQSGQQVPDDSTLRHQILERLIMDNIQLQMAKKMGITITDQALDKAIADIAAQNRMTLAQMRSRLAADGLSYDTYREQIRKEMLTSEVRNNEVRRRITILPQEVESLAKQMGNQVSGDTELNLSHILIPLPENPTQQQVDQAEDLANKLVADIKGGADFGKLAIANSADSQALKGGQMGWGKLQELPSLFAERLQSAHKGEIVGPIRSGVGFHILKVNDMRGADQTISVTEVNARHILLKPSPMMTDEQARAKLEAAAAEIKSGKTS... | Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps o... | Q7CG87 |
C6C0F7 | MTNA_MARSD | S-methyl-5-thioribose-1-phosphate isomerase | Maridesulfovibrio | MTEHIQFSPEKDALVLLDQRYLPTREDWFDCKTTDDIVEALVVMVVRGAPAIGVTAAYGCYLAGREVAGSADWKAELEKNLDKIENARPTAVNLRWAVREMKRIWAEAGDVSLDELCAIWLKRAKEIHVDDIRMCEDIGKFGGELMDDGDTIMTHCNAGALATAGYGTALGVVRGAVDQGKKVSVIANETRPFLQGARLTAYELHRDGIPVKVACDNACALLMKKGLVQKVVVGADRVTANGDAVNKIGTYGVALLAREFGIPFYVAAPVYTIDPETPTGDDVPIEDRTPTEVTHVGDHRITPEGVEVFNFAFDPTPNEL... | Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | C6C0F7 |
A2BIS8 | GGGPS_HYPBU | Phosphoglycerol geranylgeranyltransferase | Hyperthermus | MKLGKVERLLRSRVESGEKLFLLLSDPEKPISPNTVKLFEENGADVLLIGGSLNVTPYDIDEYIARLRVEGVKLPIVLFPGGLNNIAKSADAILFMTLMNSMDPYWIVGAQVAAAPIVYRLGLEAIPSAYIIVGHGGAAGHIGRALPIPYENGYIAAAYALAAEYLGARLVYFEAGSGAPKPVPVDAVAAASKVLSQALLVVGGGIREETLAAERLKAGADGVVIGTLAEKDPEKALRSSR | Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | A2BIS8 |
Q9BGQ6 | CF120_MACFA | UPF0669 protein C6orf120 homolog | Macaca | MAAPRGRAAPWTTALLLLLTSQILSPGSCADEEEVPEEWVLLHVVQGQIGAGNYSYLRLNHEGKIVLRMRSLKGDADLYVSASSLHPSFDDYELQSATCGPDAVSIPAHFRRPVGIGVYGHPSHLESEFEMKVYYDGTVEQHPFGEAAYPADGADAGQKHARAPEDASQEEESVLWTILISVLKLVLEILF | May be involved in induction of apoptosis in CD4(+) T-cells, but not CD8(+) T-cells or hepatocytes. | Q9BGQ6 |
Q98KJ4 | MIAA_RHILO | Isopentenyl-diphosphate:tRNA isopentenyltransferase | Mesorhizobium | MSGIENSGADAGEGRVKNAILIAGPTASGKSALALDLAERAGGVIVNSDSMQGYSVLDVLTARPEAADLARVPHFLYGHVHPGTAYSTGAWLRDVMKLIDDGMLSRRPVFVGGTGLYFRALAEGISEMPDIPPRIRDRWRYELKEQGAVKLHGLLLREDSRAAMQLKPTDSQRIVRALEVLDASGRSILEWQAERGRPLIDRQTARFLVIEPDRAALVDRIERRFDQMLDKGALEEVRQLAALGLDPDLPAMKAIGVRDLQAAMAGQLSFPEAIERAKIATRQYAKRQATWFRHQLGPEWQRLRPGDDLETTMQTLVANA... | Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A). | Q98KJ4 |
Q3Z6L5 | TSAD_DEHM1 | tRNA threonylcarbamoyladenosine biosynthesis protein TsaD | Dehalococcoides | MKILGIESSCDETAAAVVADGVNILSNRVSSQIDIHSRYGGVVPEVASRQHLLSILPVISDALKEARTGFDEISAIAVTNGPGLAGSLIVGVNAAKAIAAARGIPLVAVNHLHGHIYANWLSGRIPEFPCLCLTVSGGHTDLVLMKGHGQYQLLGRTRDDAAGEAFDKAARILGLSYPGGPAIDRASQDGEAVLDLPRSWIPGSHDFSFSGLKTALLRLVENGEVCSVNDAAASFQKAVVDVLVTKTLNCAHEYNVKQILLAGGVAANNLLRKQLSEQSPLPVSIPPIGLCTDNAAVIASCGYFRFISGGQDRLDMDVLP... | Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct ca... | Q3Z6L5 |
Q6NJ37 | CH601_CORDI | Chaperonin-60 1 | Corynebacterium | MAKLIAFNQEAREGILKGVDALANAVKVTLGPRGRNVVLQKAFGSPTVTNDGVTIAREIDLSDPFENLGAQLVKSVAVKTNDIAGDGTTTATLLAQAVVTEGLRNVAAGANPIELNRGIAAGSEFVVGKLRERATDVSSAADIANVATVSSRDPEVGDMVAAAMEKVGKDGVVTVEESQSIESYLDVTEGVSFDKGFLSPYFITDTDTQHAVLEQPAILLVRNKISSLPDFLPVLEKALEASKPILIIAEDVEGEPLQTLVVNSIRKTLRAVAVKAPYFGERRKAFMDDLAVVTGATVIDPEVGVNLNEAGAEVFGTARR... | Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. | Q6NJ37 |
B8IS92 | RL16_METNO | 50S ribosomal protein L16 | Methylobacterium | MLQPKKTKFRKQFKGRIHGAAKGGTDLNFGSYGLKALEPERVTARQIEAARRAITREMKRQGRVWIRIFPDVPVTQKPTEVRMGSGKGSPEYWAARVHPGRVMFEIDGVAEDIAREALRLGAAKLPVRTRFIQRIVD | Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs. | B8IS92 |
Q5XXR3 | ARHG6_RAT | Rac/Cdc42 guanine nucleotide exchange factor 6 | Rattus | MNPEERVVTWLISLGVLESPKKTICDPEEFLKSSLKNGVVLCKLISRLLPGSVEKYCQEPQTEADCIDNINDFLKGCATLQVEVFEPDDLYSGANFSKVLNTLLAVNKATEDQLSERPCGRSSSLSATTSSQTNPQAAVPSTTPEQQSEEKAAEMTENGSHQLIVKARFNFKQTNEDELSVCKGDIIYVTRVEEGGWWEGTLNGRTGWFPSNYVREIKPSERPLSPKAVKGFDTAPLTKNYYTVVLQNILDTEKEYAKELQSLLVTYLRPLQSNNNLSTVEFTCLLGNFEEVCTFQQTLCQALEECSKSPENQHKVGGCL... | Acts as a RAC1 guanine nucleotide exchange factor (GEF). | Q5XXR3 |
Q4QLI9 | ZIPA_HAEI8 | Cell division protein ZipA | Haemophilus | MDLNTILIIVGIVALVALIVHGLWSNRREKSKYFDKANKFDRTSPTSRSHTQEEMVQPNNISPNTYVENGHTPISQPTTEKLPSEAELIDYRQSDKSVDDIKISIPNTQPIYDMGNHRSEPIQPTQPQYDMPTANNVASMTLEQLEAQSQNVGFNGINSSSPELRVQLAELSHEEHQVDYNLSFNEPKAETTAQPKQTTGYIQLYLIPKSSEEFNGAKLVQALENLGFILGKDEMYHRHLDLSVASPVLFSVANLEQPGTFNAYNLAEFNTIGIVLFMQLPSPGNNLANLRMMMRAAHTLAEDLQGVILTEEQEIFDANA... | Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. | Q4QLI9 |
P0DKZ0 | CKR1B_CONRO | Conantokin Rl-B | Asprella | MQLYTYLYLLVPLVTFHLILGTGTLDHGDALTERRSTDATALKPEPVLLQKSSARSTNDNGKDTQMKRILKKRGNKARGEEELAEKAPEFARELAN | Conantokins inhibit N-methyl-D-aspartate (NMDA) receptors. This toxin has antagonist activity on the NR2B/GRIN2B subunit (IC(50)=0.1 uM) . In vivo, when delivered into the brain, is active has anticonvulsant activity in the model of epilepsy in mice . | P0DKZ0 |
Q9A8J5 | NRDR_CAUVC | Transcriptional repressor NrdR | Caulobacter | MRCPFCGHAESQVKDSRPSEDGAAIRRRRMCPECGGRFTTFERVQLRELIIVKRSGRRSPFDRDKLVRSVGLATQKRPVDPERVERMVNGIVRQLESMGETELPSSTVGEMVMKALKSLDDVAYVRYASVYRDFKETSDFAKFLTEEGLSDGGEEEL | Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. | Q9A8J5 |
Q126K7 | ACPS_POLSJ | 4'-phosphopantetheinyl transferase AcpS | unclassified Polaromonas | MIYGVGTDICDVRRIRASLERHGERLAQKILSEAELATWKERSERWPDRGVRYLATRFSAKEAFSKAIGLGMRMPMTWRHCEISKAASGKPEIVLHGPLKDWFETRQLSVHVSVTDENEYAASFCVVEKNDF | Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. | Q126K7 |
A6MMV2 | RBL_ILLOL | Ribulose bisphosphate carboxylase large chain | Illicium | MSPKTETKASVGFKAGVKDYRLTYYTPEYETKETDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVAGEENQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFVFCAEAIYKAQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQRNHGMHFRVLAKALRM... | RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site. | A6MMV2 |
A1JMW4 | RUTF_YERE8 | NADH:flavin oxidoreductase | Yersinia | MQTQSLPTDSLPASSALRSVAVDKQDFRDAMARLGSAVNIITTDGPAGRAGFTASAVCSVTDTPPTLLVCLNRSASVYSVFQQNQTLCVNTLCAEHESLSNLFGGKTPMEMRFSAARWSTLVTGCPVLSGAVASFDCHITQVISVGTHDILFCQAAAVIHNDDQHGLAYFDRCYHPLMRQSR | Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway. | A1JMW4 |
Q52221 | REP7_ECOLX | Replication-associated protein | Escherichia | MAGLKNTSYNAVHWSQLAPEEQIRFWEDYEAGRATTFLVEPERKRTKRRRGEHSTKPKCENPSWYRPERYKALKGQLGHAYNRLVKKDPVTGEQSLRMRMSRHPFYVQKRTFVGRKYAFRPEKQRLLDAIWPVLVSFSDAGTHTVGMSVTRLAEEISPKDSEGHVIPELEVTVSRLSRLLAEQVRFGVLGVSEETMWDREHRQRLPRYVWITPAGWQMLGVDMVKLHEQQQKRLRESEIRQQLIREGVLREDEDISVHAARKRWYLQRSQDALKKRREKAAASKRANRLKKLPVDQQIYEMAEYLRKRLPPDEAYFCSDD... | Binds specifically to the motif 5'-AANCYGCAA-3' (repA box) in the origin of replication. Acts preferentially in cis; binding to the repA boxes is sequential, with the boxes closest to the DnaA binding site being occupied first. It is involved in promoting open complex formation by unwinding the oriB at sequence 5'-TCTT... | Q52221 |
P26872 | RT13_MARPO | Ribosomal protein S13, mitochondrial | Marchantia | MSYILGTNLNSNKQVKIALTRIFGIGPKKAIQVCDQLGLSDTIKVNKLTKYQFDQILKIISQNYLVDSELKRVIQRDIKRLISIGCYRGFRHNAGLPLRGQRTHTNAKTCRKLRYVSIRS | Located at the top of the head of the small subunit, it contacts several helices of the 18S rRNA. | P26872 |
O82243 | GH39_ARATH | Auxin-responsive GH3-like protein 9 | Arabidopsis | MDVMKLDHDSVLKELERITSKAAEVQDNILRGILERNKDTEYLSKYMNGSKDVLEFKRAVPIIIYKDIYPYIQRIANGEDSSLITGHSITEILCSSGTSAGEPKLMPTIPEDLDRRTFLYNLIIPIVNKYITGLDKGKAMYLNFVKAETSTPCGLPIRAVLTSYYKSKHFQCRPYDPFNDLTSPIQTILCEDSNQSMYCQLLAGLIHRHKVMRLGAVFASAFLRAISYLEKKWSQLCEDIRTGSLNPMITDPGCQMAMSCLLMSPNPELASEIEEICGRSSWKGILCQLWPKAKFIEAVVTGSMAQYIPALEFFSQGKIP... | Catalyzes the synthesis of indole-3-acetic acid (IAA)-amino acid conjugates, providing a mechanism for the plant to cope with the presence of excess auxin. | O82243 |
B3SGL0 | BCH_GENLU | Beta-carotene 3-hydroxylase, chloroplastic | Gentiana | METQFLVSGRNSNIHCRIDSISSSSLTPKSSPVSTSTPTLVVFPPFKLVSKSLRTRSKPRLTVCFVLEEKELRGKLVVASDDDDGAGEVRKQREKEISASAEKLAQKLARKKSERFTYLVAAVMSSFGITSMAVLSVYYRFSWQMEGGEIPLSEMFGTFALSVGAAVGMEFWARWAHEALWHASLWHMHESHHKPREGPFELNDIFAIINAVPAIALLSYGFFHKGLIPGLCFGAGLGITVFGMAYMFVHDGLVHKRFPVGPIADVPYFRRVAAAHTLHHSDKFNGVPYGLFLGPKELEEVGGLQVLEMEINRRTKNNQS | Nonheme diiron monooxygenase involved in the biosynthesis of xanthophylls. Specific for beta-ring hydroxylations of beta-carotene. Uses ferredoxin as an electron donor. | B3SGL0 |
F4JZ24 | P4H10_ARATH | Probable prolyl 4-hydroxylase 10 | Arabidopsis | MMARPRNHRPSARKSSHSTLVFAVLIMSTFVILILLAFGILSVPSNNAGSSKANDLTSIVRKTLQRSGEDDSKNERWVEIISWEPRASVYHNFLTKEECKYLIELAKPHMEKSTVVDEKTGKSTDSRVRTSSGTFLARGRDKTIREIEKRISDFTFIPVEHGEGLQVLHYEIGQKYEPHYDYFMDEYNTRNGGQRIATVLMYLSDVEEGGETVFPAAKGNYSAVPWWNELSECGKGGLSVKPKMGDALLFWSMTPDATLDPSSLHGGCAVIKGNKWSSTKWLRVHEYKV | Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in proline-rich peptide sequences of plant glycoproteins and other proteins. Hydroxyprolines are important constituent of many plant cell wall glycoproteins such as extensins, hydroxyproline-rich glycoproteins, lectins and arabino... | F4JZ24 |
A5DV09 | GET1_LODEL | Guided entry of tail-anchored proteins 1 | Lodderomyces | MLTLDIDPYTILVTSFLILAIQKLVTVIGKQKIQLYIWQIYTKYLSHSQSIKQFNLKQKEIKDLTKQQKLISAQDEYAKWTKINRALDKLKLEVQELNETIAGEKTRIDSITKLAITLILTLPIWFLRIFCRKTALLYIRKGILPAYLEWWLALPFFKSGTIGLTCWMFVVNSVLSNLIFLISFPFTQKVERPIKPKNEQKTES | Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Together with GET2, acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. The GET complex cooperates with the HDEL receptor ERD... | A5DV09 |
Q9ZEJ7 | ISPT_TRIV2 | Isoprenyl transferase | Trichormus | MTIQQTELQELPLDLKRELLPKHVAVIMDGNGRWAKRQGLPRIMGHKRGVDALKDLLRCCRDWGIQALTAYAFSTENWKRPQEEVEFLMTLFQRVLRQELREMVEENVQIQFVGNLAALPRSLQAEISRSMEATKNNRGIRFSVATNYGGRQEILQACRAIAQKVQQGLLQPDEIDEEVFERHLYTAGIADPDLLIRTSGEMRLSNFLLWQMAYGEIYITDTLWPDFDRTEFHRALCAYQQRERRFGKV | Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | Q9ZEJ7 |
B6JJT0 | PCKA_AFIC5 | Phosphoenolpyruvate carboxykinase (ATP) | Afipia | MDQSGVRNDAFGVDKFGLKNLKAVHWNLGTAALYEYALRNGEAELTREGALCAETGEFTGRSPKDKYTVRDALTDKTMSWSTNQSITPEQFAVLHADFIKHAEGMTLYAQDLCGGADPKFQIKTRVYTELAWHSLFIRTMLRRPETAALADFVPELTIIDLPSFRADPARHGVRSPTVVAIDFTRKIVLIGGTHYAGEMKKSVFTTLNFYLPEQGVLPMHCSANVGAKGDAAVFFGLSGTGKTTLSADPQRTLLGDDEHGWGPDGVFNFEGGCYAKTIRLSREAEPAIYDASLRFGAVLENVVVDSQTRAVDFDDGSKTE... | Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. | B6JJT0 |
Q8RQN1 | AK_COREF | Aspartate kinase | Corynebacterium | MALVVQKYGGSSLESAERIRNVAERIVATKKAGNDVVVVCSAMGDTTDELLDLAAAVNPVPPAREMDMLLTAGERISNALVAMAIESLGAEAQSFTGSQAGVLTTERHGNARIVDVTPGRVREALDEGKICIVAGFQGVNKETRDVTTLGRGGSDTTAVALAAALGADVCEIYSDVDGVYTADPRIVPNAQKLERLSFEEMLELAAVGSKILVLRSVEYARAFNVPMRVRSSYSNDPGTLIAGSMEDIPMEEAVLTGVATDKSEAKVTVLGIPDKPGEAAKVFRALADAEINIDMVLQNVSSVEDGTTDITFTCPRSDGP... | Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine. | Q8RQN1 |
Q6D3L8 | END4_PECAS | Endonuclease IV | Pectobacterium | MKYIGAHVSAAGGVDQAVIRAHEIKATAFALFTKNQRQWQAAPLSTEVIDRFKAACEQYAYMSAQILPHDSYLINLGHPDGEALEKSRIAFIDEMSRCQLLGLSLLNFHPGSHLKQIEEADCLARIAESINIALAETDGVTAVIENTAGQGSNLGFRFEHLAAIIDGVEDKSRVGVCIDTCHAFAGGYDLRTEADCEATFAEFDRIVGFRYLRGMHLNDAKSAFGSRVDRHHSLGEGNIGKTAFSYIMKDTRFDGIPMILETVNPDIWADEIAWLKSEAQY | Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. | Q6D3L8 |
O66646 | LOLD_AQUAE | Lipoprotein-releasing system ATP-binding protein LolD | Aquifex | MAEILRAENIKKVIRGYEILKGISLSVKKGEFVSIIGASGSGKSTLLYILGLLDAPTEGKVFLEGKEVDYTNEKELSLLRNRKLGFVFQFHYLIPELTALENVIVPMLKMGKPKKEAKERGEYLLSELGLGDKLSRKPYELSGGEQQRVAIARALANEPILLFADEPTGNLDSANTKRVMDIFLKINEGGTSIVMVTHERELAELTHRTLEMKDGKVVGEITRV | Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner. | O66646 |
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