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The main question it aims to answer is: |
• what is the role of immune checkpoints in lung transplantation? Participants will describe pathways of rejection in lung transplantation analyzing the immune checkpoints on explanted lungs as well as trans-bronchial biopsies. conditions: Lung Transplant Rejection studyType: OBSERVATIONAL observationalModel: COHORT ti... |
<|newrecord|> nctId: NCT06302543 id: POI bone marrow briefTitle: Treatment of Premature Ovarian Insufficiency Using Bone Marrow Cells acronym: alfarah overallStatus: RECRUITING date: 2024-03-01 date: 2024-09-10 date: 2024-10-24 date: 2024-03-08 date: 2024-03-08 name: abdulmajeed hammadi class: INDUSTRY briefSummary: in... |
Autologous use of stem cells from bone marrow are alternative safe minimal manipulative products that can provide a solution to this clinical problem without the need for oocyte donation program. conditions: Premature Ovarian Insufficiency studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GR... |
<|newrecord|> nctId: NCT06302530 id: UCV/2022-2023/155 briefTitle: "Effectiveness of the Ultrasound - Guided Lengthening of the Gastrocsoleus Complex" acronym: EUGLGC overallStatus: RECRUITING date: 2024-03-15 date: 2024-08-30 date: 2025-03-15 date: 2024-03-08 date: 2024-04-23 name: Fundación Universidad Católica de Va... |
Randomization to each group will be performed using opaque sealed envelopes that will be opened in the operating room just prior to surgery. Neither the surgeon nor the patient will know the assignment until that time. |
The statistical analysis will also be performed in a blinded manner, without the statistician knowing the intervention received by each group. Only after the analysis will the groups be unblinded. |
In this way, the aim is to reduce the possibility of knowledge of the assigned treatment influencing the evaluation of the results, both on the part of the patients and of the evaluators and analysts. whoMasked: PARTICIPANT whoMasked: INVESTIGATOR count: 48 type: ESTIMATED name: Stayer name: Plantar transection measure... |
<|newrecord|> nctId: NCT06302517 id: K2020097 briefTitle: Bis Monitoring Effect on Delirium Occurrence and Nursing Quality Improvement Recovering From General Anesthesia overallStatus: COMPLETED date: 2020-09-01 date: 2022-05-31 date: 2022-08-29 date: 2024-03-08 date: 2024-03-08 name: The Fourth Affiliated Hospital of ... |
②Effects of BIS BIS Index (BIS) monitoring on the quality of nursing care in the Post-anesthesia care unit (PACU) conditions: Delirium, Postoperative studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: OTHER masking: DOUBLE whoMasked: PARTICIPANT whoMasked: CARE_PROVI... |
<|newrecord|> nctId: NCT06302504 id: Nature briefTitle: Nature-based Mindfulness Intervention Program for Family Carers overallStatus: RECRUITING date: 2023-04-15 date: 2024-03-31 date: 2024-03-31 date: 2024-03-08 date: 2024-03-08 name: The Hong Kong Polytechnic University class: OTHER briefSummary: The program integra... |
<|newrecord|> nctId: NCT06302491 id: AND017-BTH-205 briefTitle: A Study of Safety and Efficiency of AND017 in Patients With Transfusion Dependent and Non-transfusion Dependent β-thalassemia overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2025-12 date: 2026-07 date: 2024-03-08 date: 2024-03-08 name: Kind Pharmaceu... |
<|newrecord|> nctId: NCT06302478 id: KhonKaenU001 briefTitle: 5E Program for Preventing Venous Thromboembolism in Patients With Spinal Cord Disorders overallStatus: RECRUITING date: 2024-03-12 date: 2024-05-30 date: 2024-10-31 date: 2024-03-08 date: 2024-03-13 name: Khon Kaen University class: OTHER briefSummary: The g... |
* Will participants receiving the 5E program have lower rates of venous thromboembolism compared to those receiving the usual care? |
* Will participants receiving the 5E program have lower scores of venous thromboembolism signs and symptoms compared to those receiving the usual care? |
* Will the average thigh and calf circumferences of participants before and after receiving the 5E program be different? |
Participants in the intervention group will receive the 5E program, including |
* Education: health education regarding venous thromboembolism prevention |
* Elevation: leg elevation of 10-20 degrees |
* Exercise: ankle exercises |
* Enough fluid: adequate fluid uptake |
* Early application of intermittent pneumatic compression (IPC): IPC use within 48 hours after admission conditions: Venous Thromboembolism conditions: Spinal Cord Diseases conditions: Spinal Cord Injuries conditions: Nurse's Role studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: SEQUEN... |
<|newrecord|> nctId: NCT06302465 id: PKUPH-sarcoma 18 briefTitle: Narlumosbartmab Combined With Neoadjuvant Chemotherapy in Bone-derived Malignancies With Osteolytic Lesions and Multinucleated Giant Cells overallStatus: RECRUITING date: 2024-05-01 date: 2026-11-01 date: 2026-12-31 date: 2024-03-08 date: 2024-03-29 name... |
<|newrecord|> nctId: NCT06302452 id: IRB00433605 id: R01MD019173 type: NIH link: https://reporter.nih.gov/quickSearch/R01MD019173 briefTitle: Adult Trauma Centers RE-AIM at Gun Safety (ACTFAST) Prevention overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2028-02 date: 2028-02 date: 2024-03-08 date: 2024-03-08 name:... |
1. (Primary Aim 1) Increase the adoption, implementation, and maintenance of a universal firearm injury prevention intervention at three participating trauma centers in the mid-Atlantic states; |
2. (Primary Aim 2) Assess firearm injury prevention knowledge, attitudes, and safe storage practices among trauma patients treated within participating trauma centers. conditions: Firearm Injury conditions: Safety Issues studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: SEQUENTIAL intervent... |
Data are collected over multiple wedges, each 4-6 months in length. During the first wedge, none of the participating trauma centers will receive ACTFAST. During the second wedge, the first trauma center completes the Adoption and Implementation period. Over the third wedge, the first center shifts to the Maintenance p... |
<|newrecord|> nctId: NCT06302439 id: INZ701-007 briefTitle: PROPEL - A Prospective Observational Patient Registry to Evaluate ENPP1 and ABCC6 Deficiency overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2034-05 date: 2034-05 date: 2024-03-08 date: 2024-03-18 name: Inozyme Pharma class: INDUSTRY name: GACI Global br... |
<|newrecord|> nctId: NCT06302426 id: INI-4001-101 briefTitle: Trial of INI-4001 in Patients With Advanced Solid Tumours overallStatus: NOT_YET_RECRUITING date: 2024-03-29 date: 2024-08-01 date: 2026-04-30 date: 2024-03-08 date: 2024-03-08 name: Inimmune Corporation class: INDUSTRY name: Avance Clinical Pty Ltd. briefSu... |
<|newrecord|> nctId: NCT06302413 id: 1805574553; Aims 9-10 id: 1R01AA029396-01 type: NIH link: https://reporter.nih.gov/quickSearch/1R01AA029396-01 briefTitle: Enhancing Prospective Thinking in Early Recovery acronym: HOME overallStatus: RECRUITING date: 2024-02-15 date: 2027-07-31 date: 2027-07-31 date: 2024-03-08 dat... |
Will the Virtual Reality (VR) intervention decrease the number of stimulant use days? Will the VR intervention produce longer abstinence periods during follow-up visits? Will the VR intervention increase alcohol abstinence rates? Will the VR intervention increase future self-identification? Will the VR intervention inc... |
<|newrecord|> nctId: NCT06302400 id: RS-IC04 briefTitle: Individualized Dosimetry for Holmium-166 Radioembolization in Patients With Unresectable Hepatocellular Carcinoma acronym: RHEPaiR overallStatus: RECRUITING date: 2024-02-22 date: 2027-02 date: 2027-02 date: 2024-03-08 date: 2024-03-08 name: Imperial College Lond... |
* What is the safety and toxicity profile of the 166-Holmium microspheres? |
* Is the device effective in treating HCC? |
Participants will undergo a range of screening procedures to confirm they are eligible and to record their baseline results, including: |
* A Computed Tomography (CT) scan |
* A Magnetic Resonance Imaging (MRI) scan |
* Blood tests |
* Quality of life questionnaires |
Before receiving treatment with QuiremSpheres® the participant will receive a 'scout' dose of the microspheres, to check whether there is distribution of the radioactivity to other non-target areas of the body. This is measured using Single-Photon Emission Computed Tomography-CT imaging. If the distribution to non-targ... |
<|newrecord|> nctId: NCT06302387 id: BEC-LSMU(R)-27 briefTitle: Acellular Dermal Matrix Versus Tenting Technique in Peri-implant Soft Tissue Augmentation and Crestal Bone Stability overallStatus: COMPLETED date: 2018-01-01 date: 2020-04-01 date: 2023-02-01 date: 2024-03-08 date: 2024-03-08 name: Harvard Medical School ... |
<|newrecord|> nctId: NCT06302374 id: GR2001-001 briefTitle: Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Immunogenicity of GR2001 in Chinese Healthy Adults overallStatus: COMPLETED date: 2023-03-04 date: 2023-11-01 date: 2024-02-19 date: 2024-03-08 date: 2024-03-08 name: Genrix (Shanghai) Biopharmaceuti... |
In the phase II part of the study, a total of 108 healthy subjects will be enrolled. The 108 healthy subjects will be randomly assigned to the experimental group and the control group based on a ratio of 1:1:1:2:2:2.The phase II part will last for 105 days following the assessments of safety, PK, PD and ADA. primaryPur... |
<|newrecord|> nctId: NCT06302361 id: 23/54225 briefTitle: Lymphovenous Anastomosis for Breast Cancer Lymphedema overallStatus: RECRUITING date: 2024-03-01 date: 2026-06-30 date: 2026-06-30 date: 2024-03-08 date: 2024-03-08 name: Odense University Hospital class: OTHER name: Vejle Hospital name: Zealand University Hospi... |
Eligible participants are adult women with unilateral arm lymphedema who show active pitting and identifiable lymphatic vessels via indocyanine green lymphography. Inclusion involves informed consent and the ability to complete Danish questionnaires. |
Patients are recruited from the outpatient clinics of the participating hospitals and will undergo LVA surgery under either local or general anesthesia. Following the intervention, patients are seen for data collection up to twelve months. |
The study measures outcomes like arm volume changes through water displacement volumetry and arm circumferential measurements, body composition via bioimpedance, health-related quality of life through LYMPH-Q, general quality of life through SF-36, arm function via DASH, and anastomosis patency via ICG lymphography. Ad... |
The study adheres to ethical guidelines, ensuring patient safety and the integrity of the research. conditions: Lymphedema conditions: Lymphedema Arm conditions: Breast Cancer Lymphedema conditions: Lymphedema, Secondary conditions: Lymphedema; Surgical conditions: Lymphedema of Upper Limb conditions: Lymphedema, Breas... |
<|newrecord|> nctId: NCT06302348 id: PTC923-PKU-401 briefTitle: A Study of Sepiapterin in Participants With Phenylketonuria (PKU) acronym: EPIPHENY overallStatus: NOT_YET_RECRUITING date: 2024-02-29 date: 2031-02-28 date: 2031-02-28 date: 2024-03-08 date: 2024-03-08 name: PTC Therapeutics class: INDUSTRY briefSummary: ... |
<|newrecord|> nctId: NCT06302335 id: 2022-0442 briefTitle: Povidone-iodine vs Saline Solution in Colorectal Surgeries and Its Effects on the Surgical Site Infection overallStatus: RECRUITING date: 2023-01-02 date: 2027-12-31 date: 2027-12-31 date: 2024-03-08 date: 2024-03-08 name: Hospital de Clinicas de Porto Alegre c... |
<|newrecord|> nctId: NCT06302322 id: 158200-07-512-149 briefTitle: Long-term Follow up of Mucosal Tissue Height Influence on Peri-implant Bone Levels. overallStatus: COMPLETED date: 2021-01-07 date: 2022-08-15 date: 2022-10-01 date: 2024-03-08 date: 2024-03-08 name: Harvard Medical School (HMS and HSDM) class: OTHER br... |
<|newrecord|> nctId: NCT06302309 id: NL85217.091.23 briefTitle: Tackling Anxiety-related Freezing of Gait in People With Parkinson's Disease acronym: TACKLING-FOG overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2025-09 date: 2025-09 date: 2024-03-08 date: 2024-03-08 name: Radboud University Medical Center class: ... |
<|newrecord|> nctId: NCT06302296 id: Hama University/ briefTitle: Evaluating the Effect of Injectable Platelet-rich Fibrin on Accelerating Orthodontic Tooth Movement overallStatus: RECRUITING date: 2024-04-20 date: 2024-05-15 date: 2025-07-15 date: 2024-03-08 date: 2024-03-08 name: Hama University class: OTHER briefSum... |
<|newrecord|> nctId: NCT06302283 id: 114/23-EP briefTitle: Collateral Effects of Pandemics - Care for Informal Caregivers acronym: COLLPAN-3A overallStatus: ENROLLING_BY_INVITATION date: 2024-03 date: 2024-12 date: 2024-12 date: 2024-03-08 date: 2024-03-08 name: University of Bonn class: OTHER name: Wuerzburg Universit... |
<|newrecord|> nctId: NCT06302270 id: K2024-0507 briefTitle: CFTR Modulators in Pregnancy and Postpartum overallStatus: RECRUITING date: 2024-03-15 date: 2034-01-31 date: 2039-01-31 date: 2024-03-08 date: 2024-03-08 name: Region Stockholm class: OTHER_GOV name: Karolinska Institutet briefSummary: Observational study on ... |
<|newrecord|> nctId: NCT06302257 id: 0532-23-HMO briefTitle: Randomized Controlled Trial of Combined Lidocaine - Chlorprocaine in Labor Epidural Analgesia. overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2025-03-01 date: 2025-03-01 date: 2024-03-08 date: 2024-03-12 name: Hadassah Medical Organization class: OT... |
<|newrecord|> nctId: NCT06302244 id: R-21075263 briefTitle: Multimodal Neuromonitoring in Acute Brain Injury overallStatus: ACTIVE_NOT_RECRUITING date: 2017-03-27 date: 2023-06-01 date: 2024-11-01 date: 2024-03-08 date: 2024-03-12 name: Rigshospitalet, Denmark class: OTHER briefSummary: Acute brain injury due to aneury... |
The present study consists of four substudies with the overall aim of examining which factors are most influential for regulating commonly measured intracerebral parameters such as oxygenation, glucose, and lactate. Additionally, the influence of these of parameters on functional outcome and mortality will be explored. |
The individual studies are detailed below: conditions: Acute Brain Injury studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 200 type: ACTUAL measure: Correlation between systemic glucose and microdialysis glucose measure: Median goodness of fit (Pearsons R2) of the relationship b... |
<|newrecord|> nctId: NCT06302231 id: 16690919.5.0000.5347 briefTitle: Effects of Time-restricted Eating and Aerobic Exercise Training in Women With Overweight and Obesity overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2024-12 date: 2024-12 date: 2024-03-08 date: 2024-03-08 name: Federal University of Rio Grande ... |
Additionally, aerobic training performed in a fasted state appears to promote physiological adaptations that may improve the metabolic health in individuals with overweight and obesity. |
The present study investigates the effects of 8 weeks of TRE associated with aerobic training in a fasted state versus a fed state on body composition and cardiometabolic parameters in women with overweight and grade 1 obesity. conditions: Time Restricted Eating conditions: Obesity conditions: Intermittent Fasting cond... |
<|newrecord|> nctId: NCT06302218 id: 5/2024 briefTitle: ESPB vs iPACK+ACB in Total Knee Arthroplasty overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2024-09-30 date: 2025-10-30 date: 2024-03-08 date: 2024-03-08 name: Poznan University of Medical Sciences class: OTHER briefSummary: Effect of iPACK block with Ad... |
<|newrecord|> nctId: NCT06302205 id: S66232 briefTitle: A Home-based Exercise and Physical Activity Intervention After Liver Transplantation: Impact of Exercise Intensity acronym: PHOENIX-L overallStatus: RECRUITING date: 2023-03-01 date: 2026-01 date: 2026-12 date: 2024-03-08 date: 2024-04-01 name: Universitaire Zieke... |
At baseline, after three months of rehabilitation and after six months of rehabilitation, a test moment takes place at which physical fitness, cardiovascular health, liver function, and body composition will be assessed. Questionnaires are taken monthly to survey well-being, safety, quality of life, physical activity, ... |
To gather information on the potential for implementation in a real-world setting, a 15-month-long physical activity phase will start after the intervention phase. This entails a maintenance physical activity program tailored to the patients' preferences. A follow-up at UZ Leuven is planned at three and at 15 months wh... |
<|newrecord|> nctId: NCT06302192 id: 4302 briefTitle: Renal Doppler to Predict Acute Kidney Injury (AKI) in ARDS Patients. (RED-AKI Study) acronym: RED-AKI overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2026-01-31 date: 2026-06-30 date: 2024-03-08 date: 2024-03-08 name: Policlinico Hospital class: OTHER brief... |
* PRIMARY AIM: To describe the capability of IRVF demodulation at diagnosis of ARDS to predict development of AKI within 7 days from the ARDS onset |
* SECONDARY AIMS: A)Describe the capability of IRVF demodulation or pattern of IRVF (continuous, pulsatility, biphasic, monophasic) to predict development of AKI within 14 days from the ARDS onset. B) To describe the RD parameters and VexUS in the AKI and no AKI patients over time. C) Describe the impact of invasive me... |
<|newrecord|> nctId: NCT06302179 id: 140-14/24 briefTitle: Risk Factors of Venous Thromboembolism After Colorectal Cancer Surgery overallStatus: COMPLETED date: 2015-01 date: 2017-12 date: 2023-05 date: 2024-03-08 date: 2024-03-08 name: Pirogov Russian National Research Medical University class: OTHER briefSummary: Aim... |
<|newrecord|> nctId: NCT06302166 id: HafsaJaved briefTitle: Effects of HICT and Intermittent Fasting on PCOS overallStatus: NOT_YET_RECRUITING date: 2024-03-15 date: 2024-07-01 date: 2024-07-01 date: 2024-03-08 date: 2024-03-08 name: Riphah International University class: OTHER briefSummary: The goal of this randomized... |
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