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  1. paper-releases/pbisc-diffusion/updates/20261004T165054Z-rare-states-screen/diffusion/dataset/server_1/model8/plans/rare_states_screen_20261004/work/screen_v2.err +0 -0
  2. paper-releases/pbisc-diffusion/updates/20261004T165054Z-rare-states-screen/diffusion/dataset/server_1/model8/plans/rare_states_screen_20261004/work/screen_v2.log +122 -0
  3. paper-releases/pbisc-diffusion/updates/20261004T165054Z-rare-states-screen/diffusion/metadata/inference_locations.json +5 -0
  4. paper-releases/pbisc-diffusion/updates/20261004T165054Z-rare-states-screen/diffusion/metadata/request.json +139 -0
paper-releases/pbisc-diffusion/updates/20261004T165054Z-rare-states-screen/diffusion/dataset/server_1/model8/plans/rare_states_screen_20261004/work/screen_v2.err ADDED
File without changes
paper-releases/pbisc-diffusion/updates/20261004T165054Z-rare-states-screen/diffusion/dataset/server_1/model8/plans/rare_states_screen_20261004/work/screen_v2.log ADDED
@@ -0,0 +1,122 @@
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
1
+ dataset state k thin gen obs_thinned obs_native_n gen_pct obs_pct gen_over_obs spearman
2
+ dress C1Q-high monocyte (reference) 2 0.607 110 / 3,793 529 / 4,485 586 2.900 11.795 0.246 0.964
3
+ dress Cycling T/NK 2 1.000 455 / 28,601 1,295 / 26,235 1295 1.591 4.936 0.322 0.775
4
+ dress Cycling activated T (CD38/HLA-DR) 1 1.000 424 / 27,578 1,929 / 24,482 1929 1.537 7.879 0.195 0.857
5
+ dress Proliferating T (label) 1.000 1,001 / 27,578 4,226 / 24,482 4226 3.630 17.262 0.210 0.643
6
+ dress Plasmablast (label) 1.000 76 / 35,000 187 / 33,712 187 0.217 0.555 0.391 0.571
7
+ dress Plasmablast (markers) 3 0.967 108 / 35,000 529 / 33,712 549 0.309 1.569 0.197 0.607
8
+ dress MS1 monocyte (IL1R2+) 2 0.607 68 / 3,793 58 / 4,485 110 1.793 1.293 1.386 0.595
9
+ dress Cycling monocyte (Ye 2026) 1 0.607 12 / 3,793 126 / 4,485 196 0.316 2.809 0.113 0.482
10
+ dress ISG-high monocyte (positive control) 4 0.607 35 / 3,793 212 / 4,485 394 0.923 4.727 0.195 0.288
11
+ dress ISG-high T 4 1.000 31 / 27,578 318 / 24,482 318 0.112 1.299 0.087 1.000
12
+ dress DN2 / ABC B 2 0.887 23 / 1,938 89 / 2,245 98 1.187 3.964 0.299 0.286
13
+ dress HSPC 2 0.967 11 / 35,000 33 / 33,712 33 0.031 0.098 0.321 0.617
14
+ dress Cytotoxic CD4 T 3 1.000 61 / 17,909 19 / 12,541 19 0.341 0.152 2.248 0.179
15
+ dress Granulocyte-like (LDG) 2 0.967 78 / 35,000 865 / 33,712 899 0.223 2.566 0.087 0.704
16
+ dress Platelet signal in monocytes (negative control) 2 0.607 18 / 3,793 53 / 4,485 90 0.475 1.182 0.402 0.249
17
+ kawasaki C1Q-high monocyte (reference) 2 1.000 43 / 7,927 603 / 11,050 603 0.542 5.457 0.099 0.173
18
+ kawasaki Cycling T/NK 2 1.000 92 / 45,425 1,163 / 63,360 1163 0.203 1.836 0.110 0.339
19
+ kawasaki Cycling activated T (CD38/HLA-DR) 1 1.000 94 / 42,408 1,880 / 57,032 1880 0.222 3.296 0.067 0.504
20
+ kawasaki Proliferating T (label) 1.000 330 / 42,408 1,146 / 57,032 1146 0.778 2.009 0.387 0.193
21
+ kawasaki Plasmablast (label) 1.000 206 / 75,000 1,837 / 103,362 1837 0.275 1.777 0.155 0.558
22
+ kawasaki Plasmablast (markers) 3 1.000 403 / 75,000 6,780 / 103,362 6780 0.537 6.559 0.082 0.621
23
+ kawasaki MS1 monocyte (IL1R2+) 2 1.000 345 / 7,927 714 / 11,050 714 4.352 6.462 0.674 0.548
24
+ kawasaki Cycling monocyte (Ye 2026) 1 1.000 15 / 7,927 366 / 11,050 366 0.189 3.312 0.057 0.006
25
+ kawasaki ISG-high monocyte (positive control) 4 1.000 445 / 7,927 2,811 / 11,050 2811 5.614 25.439 0.221 0.211
26
+ kawasaki ISG-high T 4 1.000 161 / 42,408 2,361 / 57,032 2361 0.380 4.140 0.092 0.634
27
+ kawasaki DN2 / ABC B 2 1.000 149 / 20,998 413 / 21,517 413 0.710 1.919 0.370 -0.086
28
+ kawasaki HSPC 2 1.000 48 / 75,000 124 / 103,362 124 0.064 0.120 0.533 0.735
29
+ kawasaki Cytotoxic CD4 T 3 1.000 153 / 26,586 147 / 28,856 147 0.575 0.509 1.130 0.282
30
+ kawasaki Granulocyte-like (LDG) 2 1.000 16 / 75,000 2,974 / 103,362 2974 0.021 2.877 0.007 0.846
31
+ kawasaki Platelet signal in monocytes (negative control) 2 1.000 98 / 7,927 869 / 11,050 869 1.236 7.864 0.157 0.293
32
+ sle C1Q-high monocyte (reference) 2 0.957 109 / 21,833 1,800 / 70,901 1823 0.499 2.539 0.197 0.426
33
+ sle Cycling T/NK 2 1.000 688 / 124,845 1,553 / 238,992 1553 0.551 0.650 0.848 0.678
34
+ sle Cycling activated T (CD38/HLA-DR) 1 1.000 399 / 106,521 3,133 / 216,491 3133 0.375 1.447 0.259 0.574
35
+ sle Proliferating T (label) 1.000 561 / 106,521 1,953 / 216,491 1953 0.527 0.902 0.584 0.670
36
+ sle Plasmablast (label) 1.000 85 / 168,000 1,526 / 358,235 1526 0.051 0.426 0.119 0.190
37
+ sle Plasmablast (markers) 3 1.000 92 / 168,000 3,250 / 358,235 3250 0.055 0.907 0.060 0.307
38
+ sle MS1 monocyte (IL1R2+) 2 0.957 21 / 21,833 3,105 / 70,901 3231 0.096 4.379 0.022 -0.031
39
+ sle Cycling monocyte (Ye 2026) 1 0.957 7 / 21,833 1,200 / 70,901 1254 0.032 1.693 0.019 0.258
40
+ sle ISG-high monocyte (positive control) 4 0.957 7,372 / 21,833 27,715 / 70,901 28332 33.765 39.090 0.864 0.861
41
+ sle ISG-high T 4 1.000 5,819 / 106,521 26,345 / 216,491 26345 5.463 12.169 0.449 0.855
42
+ sle DN2 / ABC B 2 1.000 40 / 19,311 931 / 35,488 931 0.207 2.623 0.079 0.035
43
+ sle HSPC 2 1.000 12 / 168,000 265 / 358,235 265 0.007 0.074 0.097 0.127
44
+ sle Cytotoxic CD4 T 3 1.000 791 / 71,556 1,855 / 106,194 1855 1.105 1.747 0.633 0.650
45
+ sle Granulocyte-like (LDG) 2 1.000 17 / 168,000 2,697 / 358,235 2697 0.010 0.753 0.013 0.256
46
+ sle Platelet signal in monocytes (negative control) 2 0.957 403 / 21,833 3,639 / 70,901 3788 1.846 5.133 0.360 0.048
47
+ dataset state contrast obs_a_counts obs_b_counts gen_a_counts gen_b_counts obs_diff gen_diff same_direction
48
+ dress C1Q-high monocyte (reference) DRESS|none - healthy|none 53 / 1388 32 / 1949 15 / 705 11 / 1148 2.18 1.17 True
49
+ dress Cycling T/NK DRESS|none - healthy|none 882 / 5633 20 / 5650 32 / 3857 1 / 3370 15.30 0.80 True
50
+ dress Cycling activated T (CD38/HLA-DR) DRESS|none - healthy|none 1254 / 5394 57 / 4831 31 / 3696 2 / 2875 22.07 0.77 True
51
+ dress Proliferating T (label) DRESS|none - healthy|none 2361 / 5394 59 / 4831 70 / 3696 5 / 2875 42.55 1.72 True
52
+ dress Plasmablast (label) DRESS|none - healthy|none 43 / 7592 2 / 8588 12 / 5000 2 / 5000 0.54 0.20 True
53
+ dress Plasmablast (markers) DRESS|none - healthy|none 102 / 7592 72 / 8588 21 / 5000 7 / 5000 0.51 0.28 True
54
+ dress MS1 monocyte (IL1R2+) DRESS|none - healthy|none 36 / 1388 5 / 1949 17 / 705 2 / 1148 2.34 2.24 True
55
+ dress Cycling monocyte (Ye 2026) DRESS|none - healthy|none 82 / 1388 10 / 1949 1 / 705 1 / 1148 5.39 0.05 True
56
+ dress ISG-high monocyte (positive control) DRESS|none - healthy|none 41 / 1388 80 / 1949 18 / 705 9 / 1148 -1.15 1.77 False
57
+ dress ISG-high T DRESS|none - healthy|none 102 / 5394 24 / 4831 5 / 3696 1 / 2875 1.39 0.10 True
58
+ dress DN2 / ABC B DRESS|none - healthy|none 5 / 375 28 / 663 7 / 326 2 / 327 -2.89 1.54 False
59
+ dress HSPC DRESS|none - healthy|none 8 / 7592 12 / 8588 4 / 5000 1 / 5000 -0.03 0.06 False
60
+ dress Cytotoxic CD4 T DRESS|none - healthy|none 5 / 2108 7 / 2003 17 / 2477 12 / 907 -0.11 -0.64 True
61
+ dress Granulocyte-like (LDG) DRESS|none - healthy|none 261 / 7592 244 / 8588 0 / 5000 0 / 5000 0.60 0.00 False
62
+ dress Platelet signal in monocytes (negative control) DRESS|none - healthy|none 28 / 1388 22 / 1949 4 / 705 6 / 1148 0.89 0.04 True
63
+ kawasaki C1Q-high monocyte (reference) KD_before - HC 344 / 5923 45 / 1123 21 / 4450 1 / 798 2.92 0.35 True
64
+ kawasaki C1Q-high monocyte (reference) KD_before - KD_after 344 / 5923 214 / 4004 21 / 4450 21 / 2679 3.05 -0.36 False
65
+ kawasaki Cycling T/NK KD_before - HC 194 / 18293 105 / 11535 37 / 14265 4 / 9829 0.23 0.22 True
66
+ kawasaki Cycling T/NK KD_before - KD_after 194 / 18293 864 / 33532 37 / 14265 51 / 21331 -1.42 0.02 False
67
+ kawasaki Cycling activated T (CD38/HLA-DR) KD_before - HC 169 / 16366 142 / 10135 33 / 13373 4 / 9110 -0.30 0.21 False
68
+ kawasaki Cycling activated T (CD38/HLA-DR) KD_before - KD_after 169 / 16366 1569 / 30531 33 / 13373 57 / 19925 -3.95 -0.03 True
69
+ kawasaki Proliferating T (label) KD_before - HC 158 / 16366 164 / 10135 125 / 13373 50 / 9110 -0.59 0.37 False
70
+ kawasaki Proliferating T (label) KD_before - KD_after 158 / 16366 824 / 30531 125 / 13373 155 / 19925 -1.80 0.13 False
71
+ kawasaki Plasmablast (label) KD_before - HC 498 / 36717 116 / 16203 76 / 30000 24 / 15000 0.73 0.09 True
72
+ kawasaki Plasmablast (label) KD_before - KD_after 498 / 36717 1223 / 50442 76 / 30000 106 / 30000 -1.00 -0.10 True
73
+ kawasaki Plasmablast (markers) KD_before - HC 1178 / 36717 400 / 16203 185 / 30000 56 / 15000 0.70 0.24 True
74
+ kawasaki Plasmablast (markers) KD_before - KD_after 1178 / 36717 5202 / 50442 185 / 30000 162 / 30000 -7.35 0.08 False
75
+ kawasaki MS1 monocyte (IL1R2+) KD_before - HC 697 / 5923 1 / 1123 317 / 4450 0 / 798 8.39 4.28 True
76
+ kawasaki MS1 monocyte (IL1R2+) KD_before - KD_after 697 / 5923 16 / 4004 317 / 4450 28 / 2679 8.15 3.40 True
77
+ kawasaki Cycling monocyte (Ye 2026) KD_before - HC 167 / 5923 20 / 1123 14 / 4450 0 / 798 0.70 0.25 True
78
+ kawasaki Cycling monocyte (Ye 2026) KD_before - KD_after 167 / 5923 179 / 4004 14 / 4450 1 / 2679 -2.07 0.23 False
79
+ kawasaki ISG-high monocyte (positive control) KD_before - HC 624 / 5923 332 / 1123 82 / 4450 8 / 798 -17.33 0.30 False
80
+ kawasaki ISG-high monocyte (positive control) KD_before - KD_after 624 / 5923 1855 / 4004 82 / 4450 355 / 2679 -13.37 -6.55 True
81
+ kawasaki ISG-high T KD_before - HC 163 / 16366 352 / 10135 13 / 13373 5 / 9110 -2.55 0.03 False
82
+ kawasaki ISG-high T KD_before - KD_after 163 / 16366 1846 / 30531 13 / 13373 143 / 19925 -7.07 -0.68 True
83
+ kawasaki DN2 / ABC B KD_before - HC 223 / 11634 83 / 3316 74 / 11002 24 / 4266 -0.37 0.08 False
84
+ kawasaki DN2 / ABC B KD_before - KD_after 223 / 11634 107 / 6567 74 / 11002 51 / 5730 0.51 -0.27 False
85
+ kawasaki HSPC KD_before - HC 64 / 36717 10 / 16203 31 / 30000 1 / 15000 0.12 0.10 True
86
+ kawasaki HSPC KD_before - KD_after 64 / 36717 50 / 50442 31 / 30000 16 / 30000 0.08 0.05 True
87
+ kawasaki Cytotoxic CD4 T KD_before - HC 8 / 8948 27 / 4852 48 / 8516 30 / 4764 -0.45 -0.02 True
88
+ kawasaki Cytotoxic CD4 T KD_before - KD_after 8 / 8948 112 / 15056 48 / 8516 75 / 13306 -0.67 -0.03 True
89
+ kawasaki Granulocyte-like (LDG) KD_before - HC 1646 / 36717 72 / 16203 10 / 30000 0 / 15000 5.03 0.03 True
90
+ kawasaki Granulocyte-like (LDG) KD_before - KD_after 1646 / 36717 1256 / 50442 10 / 30000 6 / 30000 2.79 0.01 True
91
+ kawasaki Platelet signal in monocytes (negative control) KD_before - HC 395 / 5923 84 / 1123 57 / 4450 7 / 798 -3.75 0.44 False
92
+ kawasaki Platelet signal in monocytes (negative control) KD_before - KD_after 395 / 5923 390 / 4004 57 / 4450 34 / 2679 -3.73 -0.22 True
93
+ sle C1Q-high monocyte (reference) aSLE - aHD 347 / 9639 111 / 6619 21 / 3390 7 / 1665 1.58 -0.10 False
94
+ sle C1Q-high monocyte (reference) cSLE - cHD 1225 / 45551 117 / 9092 77 / 14947 4 / 1831 0.58 0.11 True
95
+ sle Cycling T/NK aSLE - aHD 170 / 22600 74 / 31116 172 / 16370 18 / 11915 0.58 0.91 True
96
+ sle Cycling T/NK cSLE - cHD 1166 / 121357 143 / 63919 475 / 70441 23 / 26119 1.06 0.60 True
97
+ sle Cycling activated T (CD38/HLA-DR) aSLE - aHD 416 / 20730 187 / 27704 103 / 12979 12 / 10265 1.52 0.83 True
98
+ sle Cycling activated T (CD38/HLA-DR) cSLE - cHD 2060 / 111977 470 / 56080 274 / 60156 10 / 23121 1.55 0.46 True
99
+ sle Proliferating T (label) aSLE - aHD 235 / 20730 69 / 27704 108 / 12979 13 / 10265 1.12 0.85 True
100
+ sle Proliferating T (label) cSLE - cHD 1532 / 111977 117 / 56080 426 / 60156 14 / 23121 1.84 0.73 True
101
+ sle Plasmablast (label) aSLE - aHD 143 / 35392 77 / 41440 3 / 21000 6 / 15000 0.18 -0.03 False
102
+ sle Plasmablast (label) cSLE - cHD 1084 / 195838 222 / 85565 69 / 99000 7 / 33000 0.39 0.05 True
103
+ sle Plasmablast (markers) aSLE - aHD 235 / 35392 140 / 41440 5 / 21000 7 / 15000 0.27 -0.02 False
104
+ sle Plasmablast (markers) cSLE - cHD 2434 / 195838 441 / 85565 72 / 99000 8 / 33000 0.95 0.05 True
105
+ sle MS1 monocyte (IL1R2+) aSLE - aHD 81 / 9639 38 / 6619 3 / 3390 1 / 1665 0.42 0.04 True
106
+ sle MS1 monocyte (IL1R2+) cSLE - cHD 2938 / 45551 48 / 9092 17 / 14947 0 / 1831 3.04 0.17 True
107
+ sle Cycling monocyte (Ye 2026) aSLE - aHD 156 / 9639 46 / 6619 0 / 3390 0 / 1665 1.01 0.00 False
108
+ sle Cycling monocyte (Ye 2026) cSLE - cHD 912 / 45551 86 / 9092 7 / 14947 0 / 1831 1.02 0.04 True
109
+ sle ISG-high monocyte (positive control) aSLE - aHD 4069 / 9639 253 / 6619 1175 / 3390 38 / 1665 39.05 27.61 True
110
+ sle ISG-high monocyte (positive control) cSLE - cHD 22819 / 45551 574 / 9092 6103 / 14947 56 / 1831 41.73 32.42 True
111
+ sle ISG-high T aSLE - aHD 3767 / 20730 175 / 27704 746 / 12979 29 / 10265 21.59 6.54 True
112
+ sle ISG-high T cSLE - cHD 21953 / 111977 450 / 56080 4989 / 60156 55 / 23121 23.90 9.46 True
113
+ sle DN2 / ABC B aSLE - aHD 30 / 936 23 / 2442 3 / 911 2 / 1221 2.92 0.09 True
114
+ sle DN2 / ABC B cSLE - cHD 745 / 21628 133 / 10482 21 / 12436 14 / 4743 2.85 -0.12 False
115
+ sle HSPC aSLE - aHD 37 / 35392 48 / 41440 3 / 21000 0 / 15000 -0.02 0.01 False
116
+ sle HSPC cSLE - cHD 123 / 195838 57 / 85565 9 / 99000 0 / 33000 -0.01 0.01 False
117
+ sle Cytotoxic CD4 T aSLE - aHD 187 / 9990 141 / 17255 127 / 7915 100 / 7211 2.29 0.50 True
118
+ sle Cytotoxic CD4 T cSLE - cHD 1017 / 51287 510 / 27662 408 / 39554 156 / 16876 0.99 0.09 True
119
+ sle Granulocyte-like (LDG) aSLE - aHD 284 / 35392 197 / 41440 3 / 21000 0 / 15000 0.33 0.01 True
120
+ sle Granulocyte-like (LDG) cSLE - cHD 1899 / 195838 317 / 85565 13 / 99000 1 / 33000 0.55 0.01 True
121
+ sle Platelet signal in monocytes (negative control) aSLE - aHD 605 / 9639 186 / 6619 66 / 3390 31 / 1665 3.44 0.78 True
122
+ sle Platelet signal in monocytes (negative control) cSLE - cHD 2235 / 45551 613 / 9092 286 / 14947 20 / 1831 -1.46 0.84 False
paper-releases/pbisc-diffusion/updates/20261004T165054Z-rare-states-screen/diffusion/metadata/inference_locations.json ADDED
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+ "update_id": "20261004T165054Z-rare-states-screen"
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paper-releases/pbisc-diffusion/updates/20261004T165054Z-rare-states-screen/diffusion/metadata/request.json ADDED
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+ "state": "completed"
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+ },
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+ {
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+ "host": "server_1",
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+ "kind": "log",
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+ "source": "/home/sj_server_1/PBISC/immun-pbmc-fm/model_8_sparse_data_diffusion/plans/rare_states_screen_20261004/work/corpus_v1.err",
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+ "state": "completed"
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+ "host": "server_1",
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+ "kind": "log",
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+ "source": "/home/sj_server_1/PBISC/immun-pbmc-fm/model_8_sparse_data_diffusion/plans/rare_states_screen_20261004/work/corpus_v1.log",
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+ "state": "completed"
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+ },
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+ {
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+ "host": "server_1",
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+ "kind": "log",
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+ "source": "/home/sj_server_1/PBISC/immun-pbmc-fm/model_8_sparse_data_diffusion/plans/rare_states_screen_20261004/work/corpus_v2.err",
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+ "state": "completed"
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+ },
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+ {
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+ "host": "server_1",
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+ "kind": "log",
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+ "source": "/home/sj_server_1/PBISC/immun-pbmc-fm/model_8_sparse_data_diffusion/plans/rare_states_screen_20261004/work/corpus_v2.log",
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+ "state": "completed"
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+ },
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+ {
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+ "host": "server_1",
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+ "kind": "log",
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+ "source": "/home/sj_server_1/PBISC/immun-pbmc-fm/model_8_sparse_data_diffusion/plans/rare_states_screen_20261004/work/screen_v1.err",
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+ "state": "completed"
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+ },
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+ {
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+ "host": "server_1",
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+ "kind": "log",
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+ "source": "/home/sj_server_1/PBISC/immun-pbmc-fm/model_8_sparse_data_diffusion/plans/rare_states_screen_20261004/work/screen_v1.log",
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+ "state": "completed"
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+ },
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+ {
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+ "host": "server_1",
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+ "kind": "log",
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+ "source": "/home/sj_server_1/PBISC/immun-pbmc-fm/model_8_sparse_data_diffusion/plans/rare_states_screen_20261004/work/screen_v2.err",
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+ "state": "completed"
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+ },
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+ {
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+ "host": "server_1",
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+ "kind": "log",
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+ "source": "/home/sj_server_1/PBISC/immun-pbmc-fm/model_8_sparse_data_diffusion/plans/rare_states_screen_20261004/work/screen_v2.log",
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+ "state": "completed"
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+ }
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+ ],
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+ "inference_locations": [],
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+ "project_id": "pbisc-diffusion",
138
+ "summary": "Rare disease-associated states beyond C1Q-high monocytes (plans/rare_states_screen_20261004, 2026-10-05): literature-based marker rules for 15 states scored on the existing zero-shot cross-disease arms (DRESS in corpus; Kawasaki, SLE GSE135779 not in corpus; final f01 6k E16, no new generation) and on the corpus sample. Reproduced with disease direction: Kawasaki MS1 (IL1R2+) monocytes (gen/obs 0.67), SLE ISG-high T (Spearman 0.86), SLE cycling T/NK (0.85x). Compressed: plasmablasts, C1Q-high (0.1-0.25x). Not generated: DN2/ABC B (0.08x), granulocyte-like/LDG (0.007-0.09x) although present in the corpus. Code, state rules, README, tables, logs."
139
+ }