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Archive 3 checkpoints (1-3)

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  1. paper-releases/pbisc-diffusion/updates/20261004T051658Z-behcet-c1q-lora3/diffusion/metadata/NOTE.md +5 -0
  2. paper-releases/pbisc-diffusion/updates/20261004T051658Z-behcet-c1q-lora3/diffusion/metadata/inference_locations.json +326 -0
  3. paper-releases/pbisc-diffusion/updates/20261004T051658Z-behcet-c1q-lora3/diffusion/metadata/request.json +897 -0
paper-releases/pbisc-diffusion/updates/20261004T051658Z-behcet-c1q-lora3/diffusion/metadata/NOTE.md ADDED
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+ # PBISC-diffusion update 20261004T051658Z-behcet-c1q-lora3
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+
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+ Behçet C1Q-high utility study with LoRA on the 3 recovered BD pairs (plans/behcet_c1q_lora3_20261004, 2026-10-04): LoRA r16 / 3,000 steps (LoRA-5 protocol) on BDV4/5/6; zero-shot raw, zero-shot + 3-pair calibration and LoRA-3 raw generated for all 19 bulks (5,000 cells, seeds 20260913 / 20261004); scored with the earlier Behçet wrapper unchanged. Held-out 6 BD vs 10 HC: zero-shot BD < HC (-0.94 / -0.63 pp) reverses to BD > HC with LoRA-3 (+0.91 / +1.72 pp; observed +1.3 pp); 3-pair calibration also flips it (+1.11 pp); the multi-gene C1Q-high state stays at 0.10-0.15x observed. LoRA checkpoint (sha in RUN.json), generated NPZs and read-out h5ads are on server_2 at the same paths (sha-checked moves); per-cell training counts (cells_panel6k.npz) stay local, sha in BUILD.json.
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+
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+ Payload states are recorded as supplied. Inference locations are pointers, not archived generated outputs.
paper-releases/pbisc-diffusion/updates/20261004T051658Z-behcet-c1q-lora3/diffusion/metadata/inference_locations.json ADDED
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+ "path": "/home/sj_server_1/PBISC/immun-pbmc-fm/model_8_sparse_data_diffusion/plans/behcet_c1q_lora3_20261004/generated/zs_raw_s04.npz",
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+ "experiment": "behcet_c1q_lora3_20261004",
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833
+ "receipt": "/home/sj_server_1/PBISC/immun-pbmc-fm/model_8_sparse_data_diffusion/plans/behcet_c1q_lora3_20261004/generated/zs_raw_s13.log",
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+ "seed": 20260913,
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+ "state": "completed",
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+ "steps": 50
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+ },
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+ {
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+ "cohort": "behcet_zheng2022",
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+ "experiment": "behcet_c1q_lora3_20261004",
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+ "host": "server_2",
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+ "move_marker_server_1": "/home/sj_server_1/PBISC/immun-pbmc-fm/model_8_sparse_data_diffusion/plans/behcet_c1q_lora3_20261004/work/lora3_raw_s04_poisson.h5ad.moved",
845
+ "note": "Poisson read-out (seed 20260916) of the arm's generated NPZ; moved to server_2 (sha-checked); no separate receipt file: sha256 is in the uploaded <h5ad>.moved marker and the read-out log",
846
+ "path": "/home/sj_server_1/PBISC/immun-pbmc-fm/model_8_sparse_data_diffusion/plans/behcet_c1q_lora3_20261004/work/lora3_raw_s04_poisson.h5ad",
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+ "state": "presence_only"
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+ {
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+ "cohort": "behcet_zheng2022",
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+ "experiment": "behcet_c1q_lora3_20261004",
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+ "host": "server_2",
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+ "move_marker_server_1": "/home/sj_server_1/PBISC/immun-pbmc-fm/model_8_sparse_data_diffusion/plans/behcet_c1q_lora3_20261004/work/lora3_raw_s13_poisson.h5ad.moved",
856
+ "note": "Poisson read-out (seed 20260916) of the arm's generated NPZ; moved to server_2 (sha-checked); no separate receipt file: sha256 is in the uploaded <h5ad>.moved marker and the read-out log",
857
+ "path": "/home/sj_server_1/PBISC/immun-pbmc-fm/model_8_sparse_data_diffusion/plans/behcet_c1q_lora3_20261004/work/lora3_raw_s13_poisson.h5ad",
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+ "sha256": "af9072f651517a8301fe222c8cb640af76f2e3f83a55d02f2b3509a89e5a648b",
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+ "state": "presence_only"
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+ {
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+ "cohort": "behcet_zheng2022",
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+ "experiment": "behcet_c1q_lora3_20261004",
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+ "host": "server_2",
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+ "move_marker_server_1": "/home/sj_server_1/PBISC/immun-pbmc-fm/model_8_sparse_data_diffusion/plans/behcet_c1q_lora3_20261004/work/zs_cal_s13_poisson.h5ad.moved",
867
+ "note": "Poisson read-out (seed 20260916) of the arm's generated NPZ; moved to server_2 (sha-checked); no separate receipt file: sha256 is in the uploaded <h5ad>.moved marker and the read-out log",
868
+ "path": "/home/sj_server_1/PBISC/immun-pbmc-fm/model_8_sparse_data_diffusion/plans/behcet_c1q_lora3_20261004/work/zs_cal_s13_poisson.h5ad",
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+ "sha256": "355f2f5e83b201b811e95afb360bbfb8d6cf8a0a18cb47594866af453e7887d4",
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+ "state": "presence_only"
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+ },
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+ {
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+ "artifact_role": "inference_output",
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+ "cohort": "behcet_zheng2022",
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+ "experiment": "behcet_c1q_lora3_20261004",
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+ "host": "server_2",
877
+ "move_marker_server_1": "/home/sj_server_1/PBISC/immun-pbmc-fm/model_8_sparse_data_diffusion/plans/behcet_c1q_lora3_20261004/work/zs_raw_s04_poisson.h5ad.moved",
878
+ "note": "Poisson read-out (seed 20260916) of the arm's generated NPZ; moved to server_2 (sha-checked); no separate receipt file: sha256 is in the uploaded <h5ad>.moved marker and the read-out log",
879
+ "path": "/home/sj_server_1/PBISC/immun-pbmc-fm/model_8_sparse_data_diffusion/plans/behcet_c1q_lora3_20261004/work/zs_raw_s04_poisson.h5ad",
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+ "sha256": "05b6ccc7110092ea0cf9ecc6a6d17782b8305e7ea016eb27853b047b2c77fcfc",
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+ "state": "presence_only"
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+ },
883
+ {
884
+ "artifact_role": "inference_output",
885
+ "cohort": "behcet_zheng2022",
886
+ "experiment": "behcet_c1q_lora3_20261004",
887
+ "host": "server_2",
888
+ "move_marker_server_1": "/home/sj_server_1/PBISC/immun-pbmc-fm/model_8_sparse_data_diffusion/plans/behcet_c1q_lora3_20261004/work/zs_raw_s13_poisson.h5ad.moved",
889
+ "note": "Poisson read-out (seed 20260916) of the arm's generated NPZ; moved to server_2 (sha-checked); no separate receipt file: sha256 is in the uploaded <h5ad>.moved marker and the read-out log",
890
+ "path": "/home/sj_server_1/PBISC/immun-pbmc-fm/model_8_sparse_data_diffusion/plans/behcet_c1q_lora3_20261004/work/zs_raw_s13_poisson.h5ad",
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+ "sha256": "3ce69c5ece3d54dc5d6ed5d0ac4c588dcf89739b6538c7294b2595cf6afd1202",
892
+ "state": "presence_only"
893
+ }
894
+ ],
895
+ "project_id": "pbisc-diffusion",
896
+ "summary": "Behçet C1Q-high utility study with LoRA on the 3 recovered BD pairs (plans/behcet_c1q_lora3_20261004, 2026-10-04): LoRA r16 / 3,000 steps (LoRA-5 protocol) on BDV4/5/6; zero-shot raw, zero-shot + 3-pair calibration and LoRA-3 raw generated for all 19 bulks (5,000 cells, seeds 20260913 / 20261004); scored with the earlier Behçet wrapper unchanged. Held-out 6 BD vs 10 HC: zero-shot BD < HC (-0.94 / -0.63 pp) reverses to BD > HC with LoRA-3 (+0.91 / +1.72 pp; observed +1.3 pp); 3-pair calibration also flips it (+1.11 pp); the multi-gene C1Q-high state stays at 0.10-0.15x observed. LoRA checkpoint (sha in RUN.json), generated NPZs and read-out h5ads are on server_2 at the same paths (sha-checked moves); per-cell training counts (cells_panel6k.npz) stay local, sha in BUILD.json."
897
+ }