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test
archive_info
Get information about a case from archive.
scripts/transfer-archive.py
def archive_info(database: Database, archive_case: dict) -> dict: """Get information about a case from archive.""" data = { 'collaborators': archive_case['collaborators'], 'synopsis': archive_case.get('synopsis'), 'assignees': [], 'suspects': [], 'causatives': [], ...
def archive_info(database: Database, archive_case: dict) -> dict: """Get information about a case from archive.""" data = { 'collaborators': archive_case['collaborators'], 'synopsis': archive_case.get('synopsis'), 'assignees': [], 'suspects': [], 'causatives': [], ...
[ "Get", "information", "about", "a", "case", "from", "archive", "." ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scripts/transfer-archive.py#L26-L59
[ "def", "archive_info", "(", "database", ":", "Database", ",", "archive_case", ":", "dict", ")", "->", "dict", ":", "data", "=", "{", "'collaborators'", ":", "archive_case", "[", "'collaborators'", "]", ",", "'synopsis'", ":", "archive_case", ".", "get", "(",...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
migrate_case
Migrate case information from archive.
scripts/transfer-archive.py
def migrate_case(adapter: MongoAdapter, scout_case: dict, archive_data: dict): """Migrate case information from archive.""" # update collaborators collaborators = list(set(scout_case['collaborators'] + archive_data['collaborators'])) if collaborators != scout_case['collaborators']: LOG.info(f"se...
def migrate_case(adapter: MongoAdapter, scout_case: dict, archive_data: dict): """Migrate case information from archive.""" # update collaborators collaborators = list(set(scout_case['collaborators'] + archive_data['collaborators'])) if collaborators != scout_case['collaborators']: LOG.info(f"se...
[ "Migrate", "case", "information", "from", "archive", "." ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scripts/transfer-archive.py#L62-L116
[ "def", "migrate_case", "(", "adapter", ":", "MongoAdapter", ",", "scout_case", ":", "dict", ",", "archive_data", ":", "dict", ")", ":", "# update collaborators", "collaborators", "=", "list", "(", "set", "(", "scout_case", "[", "'collaborators'", "]", "+", "ar...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
migrate
Update all information that was manually annotated from a old instance.
scripts/transfer-archive.py
def migrate(uri: str, archive_uri: str, case_id: str, dry: bool, force: bool): """Update all information that was manually annotated from a old instance.""" scout_client = MongoClient(uri) scout_database = scout_client[uri.rsplit('/', 1)[-1]] scout_adapter = MongoAdapter(database=scout_database) sco...
def migrate(uri: str, archive_uri: str, case_id: str, dry: bool, force: bool): """Update all information that was manually annotated from a old instance.""" scout_client = MongoClient(uri) scout_database = scout_client[uri.rsplit('/', 1)[-1]] scout_adapter = MongoAdapter(database=scout_database) sco...
[ "Update", "all", "information", "that", "was", "manually", "annotated", "from", "a", "old", "instance", "." ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scripts/transfer-archive.py#L125-L148
[ "def", "migrate", "(", "uri", ":", "str", ",", "archive_uri", ":", "str", ",", "case_id", ":", "str", ",", "dry", ":", "bool", ",", "force", ":", "bool", ")", ":", "scout_client", "=", "MongoClient", "(", "uri", ")", "scout_database", "=", "scout_clien...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
research
Upload research variants to cases If a case is specified, all variants found for that case will be uploaded. If no cases are specified then all cases that have 'research_requested' will have there research variants uploaded
scout/commands/load/research.py
def research(context, case_id, institute, force): """Upload research variants to cases If a case is specified, all variants found for that case will be uploaded. If no cases are specified then all cases that have 'research_requested' will have there research variants uploaded "...
def research(context, case_id, institute, force): """Upload research variants to cases If a case is specified, all variants found for that case will be uploaded. If no cases are specified then all cases that have 'research_requested' will have there research variants uploaded "...
[ "Upload", "research", "variants", "to", "cases" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/commands/load/research.py#L14-L101
[ "def", "research", "(", "context", ",", "case_id", ",", "institute", ",", "force", ")", ":", "LOG", ".", "info", "(", "\"Running scout load research\"", ")", "adapter", "=", "context", ".", "obj", "[", "'adapter'", "]", "if", "case_id", ":", "if", "not", ...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
load_hgnc
Load Genes and transcripts into the database If no resources are provided the correct ones will be fetched. Args: adapter(scout.adapter.MongoAdapter) genes(dict): If genes are already parsed ensembl_lines(iterable(str)): Lines formated with ensembl gene information ...
scout/load/hgnc_gene.py
def load_hgnc(adapter, genes=None, ensembl_lines=None, hgnc_lines=None, exac_lines=None, mim2gene_lines=None, genemap_lines=None, hpo_lines=None, transcripts_lines=None, build='37', omim_api_key=''): """Load Genes and transcripts into the database If no resources are provided the co...
def load_hgnc(adapter, genes=None, ensembl_lines=None, hgnc_lines=None, exac_lines=None, mim2gene_lines=None, genemap_lines=None, hpo_lines=None, transcripts_lines=None, build='37', omim_api_key=''): """Load Genes and transcripts into the database If no resources are provided the co...
[ "Load", "Genes", "and", "transcripts", "into", "the", "database", "If", "no", "resources", "are", "provided", "the", "correct", "ones", "will", "be", "fetched", ".", "Args", ":", "adapter", "(", "scout", ".", "adapter", ".", "MongoAdapter", ")", "genes", "...
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/load/hgnc_gene.py#L19-L59
[ "def", "load_hgnc", "(", "adapter", ",", "genes", "=", "None", ",", "ensembl_lines", "=", "None", ",", "hgnc_lines", "=", "None", ",", "exac_lines", "=", "None", ",", "mim2gene_lines", "=", "None", ",", "genemap_lines", "=", "None", ",", "hpo_lines", "=", ...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
load_hgnc_genes
Load genes into the database link_genes will collect information from all the different sources and merge it into a dictionary with hgnc_id as key and gene information as values. Args: adapter(scout.adapter.MongoAdapter) genes(dict): If genes are already parsed ensembl_lin...
scout/load/hgnc_gene.py
def load_hgnc_genes(adapter, genes = None, ensembl_lines=None, hgnc_lines=None, exac_lines=None, mim2gene_lines=None, genemap_lines=None, hpo_lines=None, build='37', omim_api_key=''): """Load genes into the database link_genes will collect information from all the different sources ...
def load_hgnc_genes(adapter, genes = None, ensembl_lines=None, hgnc_lines=None, exac_lines=None, mim2gene_lines=None, genemap_lines=None, hpo_lines=None, build='37', omim_api_key=''): """Load genes into the database link_genes will collect information from all the different sources ...
[ "Load", "genes", "into", "the", "database", "link_genes", "will", "collect", "information", "from", "all", "the", "different", "sources", "and", "merge", "it", "into", "a", "dictionary", "with", "hgnc_id", "as", "key", "and", "gene", "information", "as", "valu...
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/load/hgnc_gene.py#L61-L130
[ "def", "load_hgnc_genes", "(", "adapter", ",", "genes", "=", "None", ",", "ensembl_lines", "=", "None", ",", "hgnc_lines", "=", "None", ",", "exac_lines", "=", "None", ",", "mim2gene_lines", "=", "None", ",", "genemap_lines", "=", "None", ",", "hpo_lines", ...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
hpo
Show all hpo terms in the database
scout/commands/view/hpo.py
def hpo(context, term, description): """Show all hpo terms in the database""" LOG.info("Running scout view hpo") adapter = context.obj['adapter'] if term: term = term.upper() if not term.startswith('HP:'): while len(term) < 7: term = '0' + term ter...
def hpo(context, term, description): """Show all hpo terms in the database""" LOG.info("Running scout view hpo") adapter = context.obj['adapter'] if term: term = term.upper() if not term.startswith('HP:'): while len(term) < 7: term = '0' + term ter...
[ "Show", "all", "hpo", "terms", "in", "the", "database" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/commands/view/hpo.py#L14-L45
[ "def", "hpo", "(", "context", ",", "term", ",", "description", ")", ":", "LOG", ".", "info", "(", "\"Running scout view hpo\"", ")", "adapter", "=", "context", ".", "obj", "[", "'adapter'", "]", "if", "term", ":", "term", "=", "term", ".", "upper", "("...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
build_gene
Build a gene object Has to build the transcripts for the genes to Args: gene(dict): Parsed information from the VCF hgncid_to_gene(dict): A map from hgnc_id -> hgnc_gene objects Returns: gene_obj(dict) gene = dict( # The hgnc gene id hgnc...
scout/build/variant/gene.py
def build_gene(gene, hgncid_to_gene=None): """Build a gene object Has to build the transcripts for the genes to Args: gene(dict): Parsed information from the VCF hgncid_to_gene(dict): A map from hgnc_id -> hgnc_gene objects Returns: gene_obj(dict) ge...
def build_gene(gene, hgncid_to_gene=None): """Build a gene object Has to build the transcripts for the genes to Args: gene(dict): Parsed information from the VCF hgncid_to_gene(dict): A map from hgnc_id -> hgnc_gene objects Returns: gene_obj(dict) ge...
[ "Build", "a", "gene", "object", "Has", "to", "build", "the", "transcripts", "for", "the", "genes", "to", "Args", ":", "gene", "(", "dict", ")", ":", "Parsed", "information", "from", "the", "VCF", "hgncid_to_gene", "(", "dict", ")", ":", "A", "map", "fr...
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/build/variant/gene.py#L9-L99
[ "def", "build_gene", "(", "gene", ",", "hgncid_to_gene", "=", "None", ")", ":", "hgncid_to_gene", "=", "hgncid_to_gene", "or", "{", "}", "gene_obj", "=", "dict", "(", ")", "# This id is collected from the VCF", "# Typically annotated by VEP or snpEFF", "hgnc_id", "=",...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
create_app
Flask app factory function.
scout/server/app.py
def create_app(config_file=None, config=None): """Flask app factory function.""" app = Flask(__name__) app.config.from_pyfile('config.py') app.jinja_env.add_extension('jinja2.ext.do') if config: app.config.update(config) if config_file: app.config.from_pyfile(config_file) # ...
def create_app(config_file=None, config=None): """Flask app factory function.""" app = Flask(__name__) app.config.from_pyfile('config.py') app.jinja_env.add_extension('jinja2.ext.do') if config: app.config.update(config) if config_file: app.config.from_pyfile(config_file) # ...
[ "Flask", "app", "factory", "function", "." ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/server/app.py#L35-L76
[ "def", "create_app", "(", "config_file", "=", "None", ",", "config", "=", "None", ")", ":", "app", "=", "Flask", "(", "__name__", ")", "app", ".", "config", ".", "from_pyfile", "(", "'config.py'", ")", "app", ".", "jinja_env", ".", "add_extension", "(", ...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
configure_extensions
Configure Flask extensions.
scout/server/app.py
def configure_extensions(app): """Configure Flask extensions.""" extensions.toolbar.init_app(app) extensions.bootstrap.init_app(app) extensions.mongo.init_app(app) extensions.store.init_app(app) extensions.login_manager.init_app(app) extensions.oauth.init_app(app) extensions.mail.init_ap...
def configure_extensions(app): """Configure Flask extensions.""" extensions.toolbar.init_app(app) extensions.bootstrap.init_app(app) extensions.mongo.init_app(app) extensions.store.init_app(app) extensions.login_manager.init_app(app) extensions.oauth.init_app(app) extensions.mail.init_ap...
[ "Configure", "Flask", "extensions", "." ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/server/app.py#L79-L95
[ "def", "configure_extensions", "(", "app", ")", ":", "extensions", ".", "toolbar", ".", "init_app", "(", "app", ")", "extensions", ".", "bootstrap", ".", "init_app", "(", "app", ")", "extensions", ".", "mongo", ".", "init_app", "(", "app", ")", "extensions...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
register_blueprints
Register Flask blueprints.
scout/server/app.py
def register_blueprints(app): """Register Flask blueprints.""" app.register_blueprint(public.public_bp) app.register_blueprint(genes.genes_bp) app.register_blueprint(cases.cases_bp) app.register_blueprint(login.login_bp) app.register_blueprint(variants.variants_bp) app.register_blueprint(pan...
def register_blueprints(app): """Register Flask blueprints.""" app.register_blueprint(public.public_bp) app.register_blueprint(genes.genes_bp) app.register_blueprint(cases.cases_bp) app.register_blueprint(login.login_bp) app.register_blueprint(variants.variants_bp) app.register_blueprint(pan...
[ "Register", "Flask", "blueprints", "." ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/server/app.py#L98-L110
[ "def", "register_blueprints", "(", "app", ")", ":", "app", ".", "register_blueprint", "(", "public", ".", "public_bp", ")", "app", ".", "register_blueprint", "(", "genes", ".", "genes_bp", ")", "app", ".", "register_blueprint", "(", "cases", ".", "cases_bp", ...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
configure_email_logging
Setup logging of error/exceptions to email.
scout/server/app.py
def configure_email_logging(app): """Setup logging of error/exceptions to email.""" import logging from scout.log import TlsSMTPHandler mail_handler = TlsSMTPHandler( mailhost=app.config['MAIL_SERVER'], fromaddr=app.config['MAIL_USERNAME'], toaddrs=app.config['ADMINS'], ...
def configure_email_logging(app): """Setup logging of error/exceptions to email.""" import logging from scout.log import TlsSMTPHandler mail_handler = TlsSMTPHandler( mailhost=app.config['MAIL_SERVER'], fromaddr=app.config['MAIL_USERNAME'], toaddrs=app.config['ADMINS'], ...
[ "Setup", "logging", "of", "error", "/", "exceptions", "to", "email", "." ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/server/app.py#L146-L163
[ "def", "configure_email_logging", "(", "app", ")", ":", "import", "logging", "from", "scout", ".", "log", "import", "TlsSMTPHandler", "mail_handler", "=", "TlsSMTPHandler", "(", "mailhost", "=", "app", ".", "config", "[", "'MAIL_SERVER'", "]", ",", "fromaddr", ...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
configure_coverage
Setup coverage related extensions.
scout/server/app.py
def configure_coverage(app): """Setup coverage related extensions.""" # setup chanjo report app.config['SQLALCHEMY_TRACK_MODIFICATIONS'] = True if app.debug else False if chanjo_api: chanjo_api.init_app(app) configure_template_filters(app) # register chanjo report blueprint ...
def configure_coverage(app): """Setup coverage related extensions.""" # setup chanjo report app.config['SQLALCHEMY_TRACK_MODIFICATIONS'] = True if app.debug else False if chanjo_api: chanjo_api.init_app(app) configure_template_filters(app) # register chanjo report blueprint ...
[ "Setup", "coverage", "related", "extensions", "." ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/server/app.py#L166-L197
[ "def", "configure_coverage", "(", "app", ")", ":", "# setup chanjo report", "app", ".", "config", "[", "'SQLALCHEMY_TRACK_MODIFICATIONS'", "]", "=", "True", "if", "app", ".", "debug", "else", "False", "if", "chanjo_api", ":", "chanjo_api", ".", "init_app", "(", ...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
aliases
Show all alias symbols and how they map to ids
scout/commands/view/aliases.py
def aliases(context, build, symbol): """Show all alias symbols and how they map to ids""" LOG.info("Running scout view aliases") adapter = context.obj['adapter'] if symbol: alias_genes = {} res = adapter.gene_by_alias(symbol, build=build) for gene_obj in res: hgn...
def aliases(context, build, symbol): """Show all alias symbols and how they map to ids""" LOG.info("Running scout view aliases") adapter = context.obj['adapter'] if symbol: alias_genes = {} res = adapter.gene_by_alias(symbol, build=build) for gene_obj in res: hgn...
[ "Show", "all", "alias", "symbols", "and", "how", "they", "map", "to", "ids" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/commands/view/aliases.py#L11-L56
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90a551e2e1653a319e654c2405c2866f93d0ebb9
test
build_gene
Build a panel_gene object Args: gene_info(dict) Returns: gene_obj(dict) panel_gene = dict( hgnc_id = int, # required symbol = str, disease_associated_transcripts = list, # list of strings that represent refseq transcripts r...
scout/build/panel.py
def build_gene(gene_info, adapter): """Build a panel_gene object Args: gene_info(dict) Returns: gene_obj(dict) panel_gene = dict( hgnc_id = int, # required symbol = str, disease_associated_transcripts = list, # list of strings that...
def build_gene(gene_info, adapter): """Build a panel_gene object Args: gene_info(dict) Returns: gene_obj(dict) panel_gene = dict( hgnc_id = int, # required symbol = str, disease_associated_transcripts = list, # list of strings that...
[ "Build", "a", "panel_gene", "object", "Args", ":", "gene_info", "(", "dict", ")", "Returns", ":", "gene_obj", "(", "dict", ")", "panel_gene", "=", "dict", "(", "hgnc_id", "=", "int", "#", "required", "symbol", "=", "str" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/build/panel.py#L10-L87
[ "def", "build_gene", "(", "gene_info", ",", "adapter", ")", ":", "symbol", "=", "gene_info", ".", "get", "(", "'hgnc_symbol'", ")", "try", ":", "# A gene has to have a hgnc id", "hgnc_id", "=", "gene_info", "[", "'hgnc_id'", "]", "if", "not", "hgnc_id", ":", ...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
build_panel
Build a gene_panel object Args: panel_info(dict): A dictionary with panel information adapter (scout.adapter.MongoAdapter) Returns: panel_obj(dict) gene_panel = dict( panel_id = str, # required institute = str, # institute_id, required v...
scout/build/panel.py
def build_panel(panel_info, adapter): """Build a gene_panel object Args: panel_info(dict): A dictionary with panel information adapter (scout.adapter.MongoAdapter) Returns: panel_obj(dict) gene_panel = dict( panel_id = str, # required instit...
def build_panel(panel_info, adapter): """Build a gene_panel object Args: panel_info(dict): A dictionary with panel information adapter (scout.adapter.MongoAdapter) Returns: panel_obj(dict) gene_panel = dict( panel_id = str, # required instit...
[ "Build", "a", "gene_panel", "object" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/build/panel.py#L90-L154
[ "def", "build_panel", "(", "panel_info", ",", "adapter", ")", ":", "panel_name", "=", "panel_info", ".", "get", "(", "'panel_id'", ",", "panel_info", ".", "get", "(", "'panel_name'", ")", ")", "if", "not", "panel_name", ":", "raise", "KeyError", "(", "\"Pa...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
verified
Export variants which have been verified for an institute and write them to an excel file. Args: collaborator(str): institute id test(bool): True if the function is called for testing purposes outpath(str): path to output file Returns: written_files(int): number of writ...
scout/commands/export/variant.py
def verified(context, collaborator, test, outpath=None): """Export variants which have been verified for an institute and write them to an excel file. Args: collaborator(str): institute id test(bool): True if the function is called for testing purposes outpath(str): path to outp...
def verified(context, collaborator, test, outpath=None): """Export variants which have been verified for an institute and write them to an excel file. Args: collaborator(str): institute id test(bool): True if the function is called for testing purposes outpath(str): path to outp...
[ "Export", "variants", "which", "have", "been", "verified", "for", "an", "institute", "and", "write", "them", "to", "an", "excel", "file", "." ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/commands/export/variant.py#L29-L87
[ "def", "verified", "(", "context", ",", "collaborator", ",", "test", ",", "outpath", "=", "None", ")", ":", "written_files", "=", "0", "collaborator", "=", "collaborator", "or", "'cust000'", "LOG", ".", "info", "(", "'Exporting verified variants for cust {}'", "...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
variants
Export causatives for a collaborator in .vcf format
scout/commands/export/variant.py
def variants(context, collaborator, document_id, case_id, json): """Export causatives for a collaborator in .vcf format""" LOG.info("Running scout export variants") adapter = context.obj['adapter'] collaborator = collaborator or 'cust000' variants = export_variants( adapter, collabo...
def variants(context, collaborator, document_id, case_id, json): """Export causatives for a collaborator in .vcf format""" LOG.info("Running scout export variants") adapter = context.obj['adapter'] collaborator = collaborator or 'cust000' variants = export_variants( adapter, collabo...
[ "Export", "causatives", "for", "a", "collaborator", "in", ".", "vcf", "format" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/commands/export/variant.py#L102-L135
[ "def", "variants", "(", "context", ",", "collaborator", ",", "document_id", ",", "case_id", ",", "json", ")", ":", "LOG", ".", "info", "(", "\"Running scout export variants\"", ")", "adapter", "=", "context", ".", "obj", "[", "'adapter'", "]", "collaborator", ...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
get_vcf_entry
Get vcf entry from variant object Args: variant_obj(dict) Returns: variant_string(str): string representing variant in vcf format
scout/commands/export/variant.py
def get_vcf_entry(variant_obj, case_id=None): """ Get vcf entry from variant object Args: variant_obj(dict) Returns: variant_string(str): string representing variant in vcf format """ if variant_obj['category'] == 'snv': var_type = 'TYPE' else: ...
def get_vcf_entry(variant_obj, case_id=None): """ Get vcf entry from variant object Args: variant_obj(dict) Returns: variant_string(str): string representing variant in vcf format """ if variant_obj['category'] == 'snv': var_type = 'TYPE' else: ...
[ "Get", "vcf", "entry", "from", "variant", "object" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/commands/export/variant.py#L138-L175
[ "def", "get_vcf_entry", "(", "variant_obj", ",", "case_id", "=", "None", ")", ":", "if", "variant_obj", "[", "'category'", "]", "==", "'snv'", ":", "var_type", "=", "'TYPE'", "else", ":", "var_type", "=", "'SVTYPE'", "info_field", "=", "';'", ".", "join", ...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
serve
Start the web server.
scout/commands/serve.py
def serve(context, config, host, port, debug, livereload): """Start the web server.""" pymongo_config = dict( MONGO_HOST=context.obj['host'], MONGO_PORT=context.obj['port'], MONGO_DBNAME=context.obj['mongodb'], MONGO_USERNAME=context.obj['username'], MONGO_PASSWORD=contex...
def serve(context, config, host, port, debug, livereload): """Start the web server.""" pymongo_config = dict( MONGO_HOST=context.obj['host'], MONGO_PORT=context.obj['port'], MONGO_DBNAME=context.obj['mongodb'], MONGO_USERNAME=context.obj['username'], MONGO_PASSWORD=contex...
[ "Start", "the", "web", "server", "." ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/commands/serve.py#L22-L53
[ "def", "serve", "(", "context", ",", "config", ",", "host", ",", "port", ",", "debug", ",", "livereload", ")", ":", "pymongo_config", "=", "dict", "(", "MONGO_HOST", "=", "context", ".", "obj", "[", "'host'", "]", ",", "MONGO_PORT", "=", "context", "."...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
generate_md5_key
Generate an md5-key from a list of arguments. Args: list_of_arguments: A list of strings Returns: A md5-key object generated from the list of strings.
scout/utils/md5.py
def generate_md5_key(list_of_arguments): """ Generate an md5-key from a list of arguments. Args: list_of_arguments: A list of strings Returns: A md5-key object generated from the list of strings. """ for arg in list_of_arguments: if not isinstance(arg, string_types): ...
def generate_md5_key(list_of_arguments): """ Generate an md5-key from a list of arguments. Args: list_of_arguments: A list of strings Returns: A md5-key object generated from the list of strings. """ for arg in list_of_arguments: if not isinstance(arg, string_types): ...
[ "Generate", "an", "md5", "-", "key", "from", "a", "list", "of", "arguments", "." ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/utils/md5.py#L6-L23
[ "def", "generate_md5_key", "(", "list_of_arguments", ")", ":", "for", "arg", "in", "list_of_arguments", ":", "if", "not", "isinstance", "(", "arg", ",", "string_types", ")", ":", "raise", "SyntaxError", "(", "\"Error in generate_md5_key: \"", "\"Argument: {0} is a {1}...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
MongoAdapter.init_app
Setup via Flask.
scout/adapter/mongo/base.py
def init_app(self, app): """Setup via Flask.""" host = app.config.get('MONGO_HOST', 'localhost') port = app.config.get('MONGO_PORT', 27017) dbname = app.config['MONGO_DBNAME'] log.info("connecting to database: %s:%s/%s", host, port, dbname) self.setup(app.config['MONGO_DA...
def init_app(self, app): """Setup via Flask.""" host = app.config.get('MONGO_HOST', 'localhost') port = app.config.get('MONGO_PORT', 27017) dbname = app.config['MONGO_DBNAME'] log.info("connecting to database: %s:%s/%s", host, port, dbname) self.setup(app.config['MONGO_DA...
[ "Setup", "via", "Flask", "." ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/adapter/mongo/base.py#L60-L66
[ "def", "init_app", "(", "self", ",", "app", ")", ":", "host", "=", "app", ".", "config", ".", "get", "(", "'MONGO_HOST'", ",", "'localhost'", ")", "port", "=", "app", ".", "config", ".", "get", "(", "'MONGO_PORT'", ",", "27017", ")", "dbname", "=", ...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
MongoAdapter.setup
Setup connection to database.
scout/adapter/mongo/base.py
def setup(self, database): """Setup connection to database.""" self.db = database self.hgnc_collection = database.hgnc_gene self.user_collection = database.user self.whitelist_collection = database.whitelist self.institute_collection = database.institute self.even...
def setup(self, database): """Setup connection to database.""" self.db = database self.hgnc_collection = database.hgnc_gene self.user_collection = database.user self.whitelist_collection = database.whitelist self.institute_collection = database.institute self.even...
[ "Setup", "connection", "to", "database", "." ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/adapter/mongo/base.py#L68-L85
[ "def", "setup", "(", "self", ",", "database", ")", ":", "self", ".", "db", "=", "database", "self", ".", "hgnc_collection", "=", "database", ".", "hgnc_gene", "self", ".", "user_collection", "=", "database", ".", "user", "self", ".", "whitelist_collection", ...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
index
Create indexes for the database
scout/commands/index_command.py
def index(context, update): """Create indexes for the database""" LOG.info("Running scout index") adapter = context.obj['adapter'] if update: adapter.update_indexes() else: adapter.load_indexes()
def index(context, update): """Create indexes for the database""" LOG.info("Running scout index") adapter = context.obj['adapter'] if update: adapter.update_indexes() else: adapter.load_indexes()
[ "Create", "indexes", "for", "the", "database" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/commands/index_command.py#L19-L27
[ "def", "index", "(", "context", ",", "update", ")", ":", "LOG", ".", "info", "(", "\"Running scout index\"", ")", "adapter", "=", "context", ".", "obj", "[", "'adapter'", "]", "if", "update", ":", "adapter", ".", "update_indexes", "(", ")", "else", ":", ...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
database
Setup a scout database.
scout/commands/setup/setup_scout.py
def database(context, institute_name, user_name, user_mail, api_key): """Setup a scout database.""" LOG.info("Running scout setup database") # Fetch the omim information api_key = api_key or context.obj.get('omim_api_key') if not api_key: LOG.warning("Please provide a omim api key with --ap...
def database(context, institute_name, user_name, user_mail, api_key): """Setup a scout database.""" LOG.info("Running scout setup database") # Fetch the omim information api_key = api_key or context.obj.get('omim_api_key') if not api_key: LOG.warning("Please provide a omim api key with --ap...
[ "Setup", "a", "scout", "database", "." ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/commands/setup/setup_scout.py#L46-L70
[ "def", "database", "(", "context", ",", "institute_name", ",", "user_name", ",", "user_mail", ",", "api_key", ")", ":", "LOG", ".", "info", "(", "\"Running scout setup database\"", ")", "# Fetch the omim information", "api_key", "=", "api_key", "or", "context", "....
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
demo
Setup a scout demo instance. This instance will be populated with a case, a gene panel and some variants.
scout/commands/setup/setup_scout.py
def demo(context): """Setup a scout demo instance. This instance will be populated with a case, a gene panel and some variants. """ LOG.info("Running scout setup demo") institute_name = context.obj['institute_name'] user_name = context.obj['user_name'] user_mail = context.obj['user_mail']...
def demo(context): """Setup a scout demo instance. This instance will be populated with a case, a gene panel and some variants. """ LOG.info("Running scout setup demo") institute_name = context.obj['institute_name'] user_name = context.obj['user_name'] user_mail = context.obj['user_mail']...
[ "Setup", "a", "scout", "demo", "instance", ".", "This", "instance", "will", "be", "populated", "with", "a", "case", "a", "gene", "panel", "and", "some", "variants", "." ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/commands/setup/setup_scout.py#L74-L93
[ "def", "demo", "(", "context", ")", ":", "LOG", ".", "info", "(", "\"Running scout setup demo\"", ")", "institute_name", "=", "context", ".", "obj", "[", "'institute_name'", "]", "user_name", "=", "context", ".", "obj", "[", "'user_name'", "]", "user_mail", ...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
setup
Setup scout instances.
scout/commands/setup/setup_scout.py
def setup(context, institute, user_mail, user_name): """ Setup scout instances. """ context.obj['institute_name'] = institute context.obj['user_name'] = user_name context.obj['user_mail'] = user_mail if context.invoked_subcommand == 'demo': # Update context.obj settings here ...
def setup(context, institute, user_mail, user_name): """ Setup scout instances. """ context.obj['institute_name'] = institute context.obj['user_name'] = user_name context.obj['user_mail'] = user_mail if context.invoked_subcommand == 'demo': # Update context.obj settings here ...
[ "Setup", "scout", "instances", "." ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/commands/setup/setup_scout.py#L118-L159
[ "def", "setup", "(", "context", ",", "institute", ",", "user_mail", ",", "user_name", ")", ":", "context", ".", "obj", "[", "'institute_name'", "]", "=", "institute", "context", ".", "obj", "[", "'user_name'", "]", "=", "user_name", "context", ".", "obj", ...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
institutes
Show all institutes in the database
scout/commands/view/institutes.py
def institutes(context, institute_id, json): """Show all institutes in the database""" LOG.info("Running scout view institutes") adapter = context.obj['adapter'] if institute_id: institute_objs = [] institute_obj = adapter.institute(institute_id) if not institute_obj: ...
def institutes(context, institute_id, json): """Show all institutes in the database""" LOG.info("Running scout view institutes") adapter = context.obj['adapter'] if institute_id: institute_objs = [] institute_obj = adapter.institute(institute_id) if not institute_obj: ...
[ "Show", "all", "institutes", "in", "the", "database" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/commands/view/institutes.py#L16-L51
[ "def", "institutes", "(", "context", ",", "institute_id", ",", "json", ")", ":", "LOG", ".", "info", "(", "\"Running scout view institutes\"", ")", "adapter", "=", "context", ".", "obj", "[", "'adapter'", "]", "if", "institute_id", ":", "institute_objs", "=", ...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
parse_genetic_models
Parse the genetic models entry of a vcf Args: models_info(str): The raw vcf information case_id(str) Returns: genetic_models(list)
scout/parse/variant/models.py
def parse_genetic_models(models_info, case_id): """Parse the genetic models entry of a vcf Args: models_info(str): The raw vcf information case_id(str) Returns: genetic_models(list) """ genetic_models = [] if models_info: for family_info in models_info.split(',...
def parse_genetic_models(models_info, case_id): """Parse the genetic models entry of a vcf Args: models_info(str): The raw vcf information case_id(str) Returns: genetic_models(list) """ genetic_models = [] if models_info: for family_info in models_info.split(',...
[ "Parse", "the", "genetic", "models", "entry", "of", "a", "vcf" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/parse/variant/models.py#L2-L20
[ "def", "parse_genetic_models", "(", "models_info", ",", "case_id", ")", ":", "genetic_models", "=", "[", "]", "if", "models_info", ":", "for", "family_info", "in", "models_info", ".", "split", "(", "','", ")", ":", "splitted_info", "=", "family_info", ".", "...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
panels
Show all gene panels in the database
scout/commands/view/panels.py
def panels(context, institute): """Show all gene panels in the database""" LOG.info("Running scout view panels") adapter = context.obj['adapter'] panel_objs = adapter.gene_panels(institute_id=institute) if panel_objs.count() == 0: LOG.info("No panels found") context.abort() clic...
def panels(context, institute): """Show all gene panels in the database""" LOG.info("Running scout view panels") adapter = context.obj['adapter'] panel_objs = adapter.gene_panels(institute_id=institute) if panel_objs.count() == 0: LOG.info("No panels found") context.abort() clic...
[ "Show", "all", "gene", "panels", "in", "the", "database" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/commands/view/panels.py#L12-L29
[ "def", "panels", "(", "context", ",", "institute", ")", ":", "LOG", ".", "info", "(", "\"Running scout view panels\"", ")", "adapter", "=", "context", ".", "obj", "[", "'adapter'", "]", "panel_objs", "=", "adapter", ".", "gene_panels", "(", "institute_id", "...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
InstituteHandler.add_institute
Add a institute to the database Args: institute_obj(Institute)
scout/adapter/mongo/institute.py
def add_institute(self, institute_obj): """Add a institute to the database Args: institute_obj(Institute) """ internal_id = institute_obj['internal_id'] display_name = institute_obj['internal_id'] # Check if institute already exists if self.i...
def add_institute(self, institute_obj): """Add a institute to the database Args: institute_obj(Institute) """ internal_id = institute_obj['internal_id'] display_name = institute_obj['internal_id'] # Check if institute already exists if self.i...
[ "Add", "a", "institute", "to", "the", "database" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/adapter/mongo/institute.py#L16-L36
[ "def", "add_institute", "(", "self", ",", "institute_obj", ")", ":", "internal_id", "=", "institute_obj", "[", "'internal_id'", "]", "display_name", "=", "institute_obj", "[", "'internal_id'", "]", "# Check if institute already exists", "if", "self", ".", "institute",...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
InstituteHandler.update_institute
Update the information for an institute Args: internal_id(str): The internal institute id sanger_recipient(str): Email adress to add for sanger order coverage_cutoff(int): Update coverage cutoff frequency_cutoff(float): New frequency cutoff display_na...
scout/adapter/mongo/institute.py
def update_institute(self, internal_id, sanger_recipient=None, coverage_cutoff=None, frequency_cutoff=None, display_name=None, remove_sanger=None, phenotype_groups=None, group_abbreviations=None, add_groups=None): """Update the information for an institute ...
def update_institute(self, internal_id, sanger_recipient=None, coverage_cutoff=None, frequency_cutoff=None, display_name=None, remove_sanger=None, phenotype_groups=None, group_abbreviations=None, add_groups=None): """Update the information for an institute ...
[ "Update", "the", "information", "for", "an", "institute" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/adapter/mongo/institute.py#L38-L129
[ "def", "update_institute", "(", "self", ",", "internal_id", ",", "sanger_recipient", "=", "None", ",", "coverage_cutoff", "=", "None", ",", "frequency_cutoff", "=", "None", ",", "display_name", "=", "None", ",", "remove_sanger", "=", "None", ",", "phenotype_grou...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
InstituteHandler.institute
Featch a single institute from the backend Args: institute_id(str) Returns: Institute object
scout/adapter/mongo/institute.py
def institute(self, institute_id): """Featch a single institute from the backend Args: institute_id(str) Returns: Institute object """ LOG.debug("Fetch institute {}".format(institute_id)) institute_obj = self.institute_collection....
def institute(self, institute_id): """Featch a single institute from the backend Args: institute_id(str) Returns: Institute object """ LOG.debug("Fetch institute {}".format(institute_id)) institute_obj = self.institute_collection....
[ "Featch", "a", "single", "institute", "from", "the", "backend" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/adapter/mongo/institute.py#L131-L147
[ "def", "institute", "(", "self", ",", "institute_id", ")", ":", "LOG", ".", "debug", "(", "\"Fetch institute {}\"", ".", "format", "(", "institute_id", ")", ")", "institute_obj", "=", "self", ".", "institute_collection", ".", "find_one", "(", "{", "'_id'", "...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
InstituteHandler.institutes
Fetch all institutes. Args: institute_ids(list(str)) Returns: res(pymongo.Cursor)
scout/adapter/mongo/institute.py
def institutes(self, institute_ids=None): """Fetch all institutes. Args: institute_ids(list(str)) Returns: res(pymongo.Cursor) """ query = {} if institute_ids: query['_id'] = {'$in': institute_ids} LOG.debug("F...
def institutes(self, institute_ids=None): """Fetch all institutes. Args: institute_ids(list(str)) Returns: res(pymongo.Cursor) """ query = {} if institute_ids: query['_id'] = {'$in': institute_ids} LOG.debug("F...
[ "Fetch", "all", "institutes", ".", "Args", ":", "institute_ids", "(", "list", "(", "str", "))", "Returns", ":", "res", "(", "pymongo", ".", "Cursor", ")" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/adapter/mongo/institute.py#L149-L162
[ "def", "institutes", "(", "self", ",", "institute_ids", "=", "None", ")", ":", "query", "=", "{", "}", "if", "institute_ids", ":", "query", "[", "'_id'", "]", "=", "{", "'$in'", ":", "institute_ids", "}", "LOG", ".", "debug", "(", "\"Fetching all institu...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
match_date
Check if a string is a valid date Args: date(str) Returns: bool
scout/utils/date.py
def match_date(date): """Check if a string is a valid date Args: date(str) Returns: bool """ date_pattern = re.compile("^(19|20)\d\d[- /.](0[1-9]|1[012])[- /.](0[1-9]|[12][0-9]|3[01])") if re.match(date_pattern, date): return True return False
def match_date(date): """Check if a string is a valid date Args: date(str) Returns: bool """ date_pattern = re.compile("^(19|20)\d\d[- /.](0[1-9]|1[012])[- /.](0[1-9]|[12][0-9]|3[01])") if re.match(date_pattern, date): return True return False
[ "Check", "if", "a", "string", "is", "a", "valid", "date" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/utils/date.py#L4-L17
[ "def", "match_date", "(", "date", ")", ":", "date_pattern", "=", "re", ".", "compile", "(", "\"^(19|20)\\d\\d[- /.](0[1-9]|1[012])[- /.](0[1-9]|[12][0-9]|3[01])\"", ")", "if", "re", ".", "match", "(", "date_pattern", ",", "date", ")", ":", "return", "True", "retur...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
get_date
Return a datetime object if there is a valid date Raise exception if date is not valid Return todays date if no date where added Args: date(str) date_format(str) Returns: date_obj(datetime.datetime)
scout/utils/date.py
def get_date(date, date_format = None): """Return a datetime object if there is a valid date Raise exception if date is not valid Return todays date if no date where added Args: date(str) date_format(str) Returns: date_obj(datetime.datetime) ...
def get_date(date, date_format = None): """Return a datetime object if there is a valid date Raise exception if date is not valid Return todays date if no date where added Args: date(str) date_format(str) Returns: date_obj(datetime.datetime) ...
[ "Return", "a", "datetime", "object", "if", "there", "is", "a", "valid", "date" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/utils/date.py#L19-L50
[ "def", "get_date", "(", "date", ",", "date_format", "=", "None", ")", ":", "date_obj", "=", "datetime", ".", "datetime", ".", "now", "(", ")", "if", "date", ":", "if", "date_format", ":", "date_obj", "=", "datetime", ".", "datetime", ".", "strptime", "...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
hpo_genes
Export a list of genes based on hpo terms
scout/commands/export/hpo.py
def hpo_genes(context, hpo_term): """Export a list of genes based on hpo terms""" LOG.info("Running scout export hpo_genes") adapter = context.obj['adapter'] header = ["#Gene_id\tCount"] if not hpo_term: LOG.warning("Please use at least one hpo term") context.abort() for l...
def hpo_genes(context, hpo_term): """Export a list of genes based on hpo terms""" LOG.info("Running scout export hpo_genes") adapter = context.obj['adapter'] header = ["#Gene_id\tCount"] if not hpo_term: LOG.warning("Please use at least one hpo term") context.abort() for l...
[ "Export", "a", "list", "of", "genes", "based", "on", "hpo", "terms" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/commands/export/hpo.py#L10-L25
[ "def", "hpo_genes", "(", "context", ",", "hpo_term", ")", ":", "LOG", ".", "info", "(", "\"Running scout export hpo_genes\"", ")", "adapter", "=", "context", ".", "obj", "[", "'adapter'", "]", "header", "=", "[", "\"#Gene_id\\tCount\"", "]", "if", "not", "hp...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
parse_genes
Parse transcript information and get the gene information from there. Use hgnc_id as identifier for genes and ensembl transcript id to identify transcripts Args: transcripts(iterable(dict)) Returns: genes (list(dict)): A list with dictionaries that represents genes
scout/parse/variant/gene.py
def parse_genes(transcripts): """Parse transcript information and get the gene information from there. Use hgnc_id as identifier for genes and ensembl transcript id to identify transcripts Args: transcripts(iterable(dict)) Returns: genes (list(dict)): A list with dictionaries th...
def parse_genes(transcripts): """Parse transcript information and get the gene information from there. Use hgnc_id as identifier for genes and ensembl transcript id to identify transcripts Args: transcripts(iterable(dict)) Returns: genes (list(dict)): A list with dictionaries th...
[ "Parse", "transcript", "information", "and", "get", "the", "gene", "information", "from", "there", ".", "Use", "hgnc_id", "as", "identifier", "for", "genes", "and", "ensembl", "transcript", "id", "to", "identify", "transcripts", "Args", ":", "transcripts", "(", ...
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/parse/variant/gene.py#L16-L114
[ "def", "parse_genes", "(", "transcripts", ")", ":", "# Dictionary to group the transcripts by hgnc_id", "genes_to_transcripts", "=", "{", "}", "# List with all genes and there transcripts", "genes", "=", "[", "]", "hgvs_identifier", "=", "None", "canonical_transcript", "=", ...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
parse_rank_score
Parse the rank score Args: rank_score_entry(str): The raw rank score entry case_id(str) Returns: rank_score(float)
scout/parse/variant/rank_score.py
def parse_rank_score(rank_score_entry, case_id): """Parse the rank score Args: rank_score_entry(str): The raw rank score entry case_id(str) Returns: rank_score(float) """ rank_score = None if rank_score_entry: for family_info in rank_score_en...
def parse_rank_score(rank_score_entry, case_id): """Parse the rank score Args: rank_score_entry(str): The raw rank score entry case_id(str) Returns: rank_score(float) """ rank_score = None if rank_score_entry: for family_info in rank_score_en...
[ "Parse", "the", "rank", "score" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/parse/variant/rank_score.py#L3-L19
[ "def", "parse_rank_score", "(", "rank_score_entry", ",", "case_id", ")", ":", "rank_score", "=", "None", "if", "rank_score_entry", ":", "for", "family_info", "in", "rank_score_entry", ".", "split", "(", "','", ")", ":", "splitted_info", "=", "family_info", ".", ...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
user
Add a user to the database.
scout/commands/load/user.py
def user(context, institute_id, user_name, user_mail, admin): """Add a user to the database.""" adapter = context.obj['adapter'] institutes = [] for institute in institute_id: institute_obj = adapter.institute(institute_id=institute) if not institute_obj: LOG.warning("Insti...
def user(context, institute_id, user_name, user_mail, admin): """Add a user to the database.""" adapter = context.obj['adapter'] institutes = [] for institute in institute_id: institute_obj = adapter.institute(institute_id=institute) if not institute_obj: LOG.warning("Insti...
[ "Add", "a", "user", "to", "the", "database", "." ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/commands/load/user.py#L24-L51
[ "def", "user", "(", "context", ",", "institute_id", ",", "user_name", ",", "user_mail", ",", "admin", ")", ":", "adapter", "=", "context", ".", "obj", "[", "'adapter'", "]", "institutes", "=", "[", "]", "for", "institute", "in", "institute_id", ":", "ins...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
parse_transcripts
Parse transcript information from VCF variants Args: raw_transcripts(iterable(dict)): An iterable with raw transcript information Yields: transcript(dict) A dictionary with transcript information
scout/parse/variant/transcript.py
def parse_transcripts(raw_transcripts, allele=None): """Parse transcript information from VCF variants Args: raw_transcripts(iterable(dict)): An iterable with raw transcript information Yields: transcript(dict) A dictionary with transcript informat...
def parse_transcripts(raw_transcripts, allele=None): """Parse transcript information from VCF variants Args: raw_transcripts(iterable(dict)): An iterable with raw transcript information Yields: transcript(dict) A dictionary with transcript informat...
[ "Parse", "transcript", "information", "from", "VCF", "variants" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/parse/variant/transcript.py#L9-L201
[ "def", "parse_transcripts", "(", "raw_transcripts", ",", "allele", "=", "None", ")", ":", "for", "entry", "in", "raw_transcripts", ":", "transcript", "=", "{", "}", "# There can be several functional annotations for one variant", "functional_annotations", "=", "entry", ...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
check_connection
Check if a connection could be made to the mongo process specified Args: host(str) port(int) username(str) password(str) authdb (str): database to to for authentication max_delay(int): Number of milliseconds to wait for connection Returns: bool: If conne...
scout/adapter/utils.py
def check_connection(host='localhost', port=27017, username=None, password=None, authdb=None, max_delay=1): """Check if a connection could be made to the mongo process specified Args: host(str) port(int) username(str) password(str) authdb (str): data...
def check_connection(host='localhost', port=27017, username=None, password=None, authdb=None, max_delay=1): """Check if a connection could be made to the mongo process specified Args: host(str) port(int) username(str) password(str) authdb (str): data...
[ "Check", "if", "a", "connection", "could", "be", "made", "to", "the", "mongo", "process", "specified" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/adapter/utils.py#L17-L50
[ "def", "check_connection", "(", "host", "=", "'localhost'", ",", "port", "=", "27017", ",", "username", "=", "None", ",", "password", "=", "None", ",", "authdb", "=", "None", ",", "max_delay", "=", "1", ")", ":", "#uri looks like:", "#mongodb://[username:pas...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
MongoDB.init_app
Initialize from flask
scout/server/extensions.py
def init_app(self, app): """Initialize from flask""" uri = app.config.get("MONGO_URI", None) db_name = app.config.get("MONGO_DBNAME", 'scout') try: client = get_connection( host = app.config.get("MONGO_HOST", 'localhost'), por...
def init_app(self, app): """Initialize from flask""" uri = app.config.get("MONGO_URI", None) db_name = app.config.get("MONGO_DBNAME", 'scout') try: client = get_connection( host = app.config.get("MONGO_HOST", 'localhost'), por...
[ "Initialize", "from", "flask" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/server/extensions.py#L43-L63
[ "def", "init_app", "(", "self", ",", "app", ")", ":", "uri", "=", "app", ".", "config", ".", "get", "(", "\"MONGO_URI\"", ",", "None", ")", "db_name", "=", "app", ".", "config", ".", "get", "(", "\"MONGO_DBNAME\"", ",", "'scout'", ")", "try", ":", ...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
institutes
Display a list of all user institutes.
scout/server/blueprints/institutes/views.py
def institutes(): """Display a list of all user institutes.""" institute_objs = user_institutes(store, current_user) institutes = [] for ins_obj in institute_objs: sanger_recipients = [] for user_mail in ins_obj.get('sanger_recipients',[]): user_obj = store.user(user_mail) ...
def institutes(): """Display a list of all user institutes.""" institute_objs = user_institutes(store, current_user) institutes = [] for ins_obj in institute_objs: sanger_recipients = [] for user_mail in ins_obj.get('sanger_recipients',[]): user_obj = store.user(user_mail) ...
[ "Display", "a", "list", "of", "all", "user", "institutes", "." ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/server/blueprints/institutes/views.py#L17-L41
[ "def", "institutes", "(", ")", ":", "institute_objs", "=", "user_institutes", "(", "store", ",", "current_user", ")", "institutes", "=", "[", "]", "for", "ins_obj", "in", "institute_objs", ":", "sanger_recipients", "=", "[", "]", "for", "user_mail", "in", "i...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
load_delivery_report
Load a delivery report into a case in the database If the report already exists the function will exit. If the user want to load a report that is already in the database 'update' has to be 'True' Args: adapter (MongoAdapter): Connection to the database report_path (string): P...
scout/load/report.py
def load_delivery_report(adapter: MongoAdapter, report_path: str, case_id: str, update: bool = False): """ Load a delivery report into a case in the database If the report already exists the function will exit. If the user want to l...
def load_delivery_report(adapter: MongoAdapter, report_path: str, case_id: str, update: bool = False): """ Load a delivery report into a case in the database If the report already exists the function will exit. If the user want to l...
[ "Load", "a", "delivery", "report", "into", "a", "case", "in", "the", "database" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/load/report.py#L10-L48
[ "def", "load_delivery_report", "(", "adapter", ":", "MongoAdapter", ",", "report_path", ":", "str", ",", "case_id", ":", "str", ",", "update", ":", "bool", "=", "False", ")", ":", "case_obj", "=", "adapter", ".", "case", "(", "case_id", "=", "case_id", "...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
build_transcript
Build a transcript object These represents the transcripts that are parsed from the VCF, not the transcript definitions that are collected from ensembl. Args: transcript(dict): Parsed transcript information Returns: transcript_obj(dict)
scout/build/variant/transcript.py
def build_transcript(transcript, build='37'): """Build a transcript object These represents the transcripts that are parsed from the VCF, not the transcript definitions that are collected from ensembl. Args: transcript(dict): Parsed transcript information Returns: ...
def build_transcript(transcript, build='37'): """Build a transcript object These represents the transcripts that are parsed from the VCF, not the transcript definitions that are collected from ensembl. Args: transcript(dict): Parsed transcript information Returns: ...
[ "Build", "a", "transcript", "object", "These", "represents", "the", "transcripts", "that", "are", "parsed", "from", "the", "VCF", "not", "the", "transcript", "definitions", "that", "are", "collected", "from", "ensembl", ".", "Args", ":", "transcript", "(", "di...
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/build/variant/transcript.py#L5-L75
[ "def", "build_transcript", "(", "transcript", ",", "build", "=", "'37'", ")", ":", "# Transcripts has to have an id", "transcript_id", "=", "transcript", "[", "'transcript_id'", "]", "transcript_obj", "=", "dict", "(", "transcript_id", "=", "transcript_id", ")", "# ...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
UserHandler.update_user
Update an existing user. Args: user_obj(dict) Returns: updated_user(dict)
scout/adapter/mongo/user.py
def update_user(self, user_obj): """Update an existing user. Args: user_obj(dict) Returns: updated_user(dict) """ LOG.info("Updating user %s", user_obj['_id']) updated_user = self.user_collection.find_one_...
def update_user(self, user_obj): """Update an existing user. Args: user_obj(dict) Returns: updated_user(dict) """ LOG.info("Updating user %s", user_obj['_id']) updated_user = self.user_collection.find_one_...
[ "Update", "an", "existing", "user", ".", "Args", ":", "user_obj", "(", "dict", ")", "Returns", ":", "updated_user", "(", "dict", ")" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/adapter/mongo/user.py#L14-L30
[ "def", "update_user", "(", "self", ",", "user_obj", ")", ":", "LOG", ".", "info", "(", "\"Updating user %s\"", ",", "user_obj", "[", "'_id'", "]", ")", "updated_user", "=", "self", ".", "user_collection", ".", "find_one_and_replace", "(", "{", "'_id'", ":", ...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
UserHandler.add_user
Add a user object to the database Args: user_obj(scout.models.User): A dictionary with user information Returns: user_info(dict): a copy of what was inserted
scout/adapter/mongo/user.py
def add_user(self, user_obj): """Add a user object to the database Args: user_obj(scout.models.User): A dictionary with user information Returns: user_info(dict): a copy of what was inserted """ LOG.info("Adding user %s to the dat...
def add_user(self, user_obj): """Add a user object to the database Args: user_obj(scout.models.User): A dictionary with user information Returns: user_info(dict): a copy of what was inserted """ LOG.info("Adding user %s to the dat...
[ "Add", "a", "user", "object", "to", "the", "database" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/adapter/mongo/user.py#L32-L51
[ "def", "add_user", "(", "self", ",", "user_obj", ")", ":", "LOG", ".", "info", "(", "\"Adding user %s to the database\"", ",", "user_obj", "[", "'email'", "]", ")", "if", "not", "'_id'", "in", "user_obj", ":", "user_obj", "[", "'_id'", "]", "=", "user_obj"...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
UserHandler.users
Return all users from the database Args: institute(str): A institute_id Returns: res(pymongo.Cursor): A cursor with users
scout/adapter/mongo/user.py
def users(self, institute=None): """Return all users from the database Args: institute(str): A institute_id Returns: res(pymongo.Cursor): A cursor with users """ query = {} if institute: LOG.info("Fetch...
def users(self, institute=None): """Return all users from the database Args: institute(str): A institute_id Returns: res(pymongo.Cursor): A cursor with users """ query = {} if institute: LOG.info("Fetch...
[ "Return", "all", "users", "from", "the", "database", "Args", ":", "institute", "(", "str", ")", ":", "A", "institute_id", "Returns", ":", "res", "(", "pymongo", ".", "Cursor", ")", ":", "A", "cursor", "with", "users" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/adapter/mongo/user.py#L53-L70
[ "def", "users", "(", "self", ",", "institute", "=", "None", ")", ":", "query", "=", "{", "}", "if", "institute", ":", "LOG", ".", "info", "(", "\"Fetching all users from institute %s\"", ",", "institute", ")", "query", "=", "{", "'institutes'", ":", "{", ...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
UserHandler.user
Fetch a user from the database. Args: email(str) Returns: user_obj(dict)
scout/adapter/mongo/user.py
def user(self, email): """Fetch a user from the database. Args: email(str) Returns: user_obj(dict) """ LOG.info("Fetching user %s", email) user_obj = self.user_collection.find_one({'_id': email}) return us...
def user(self, email): """Fetch a user from the database. Args: email(str) Returns: user_obj(dict) """ LOG.info("Fetching user %s", email) user_obj = self.user_collection.find_one({'_id': email}) return us...
[ "Fetch", "a", "user", "from", "the", "database", ".", "Args", ":", "email", "(", "str", ")", "Returns", ":", "user_obj", "(", "dict", ")" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/adapter/mongo/user.py#L72-L84
[ "def", "user", "(", "self", ",", "email", ")", ":", "LOG", ".", "info", "(", "\"Fetching user %s\"", ",", "email", ")", "user_obj", "=", "self", ".", "user_collection", ".", "find_one", "(", "{", "'_id'", ":", "email", "}", ")", "return", "user_obj" ]
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
UserHandler.delete_user
Delete a user from the database Args: email(str) Returns: user_obj(dict)
scout/adapter/mongo/user.py
def delete_user(self, email): """Delete a user from the database Args: email(str) Returns: user_obj(dict) """ LOG.info("Deleting user %s", email) user_obj = self.user_collection.delete_one({'_id': email}) ret...
def delete_user(self, email): """Delete a user from the database Args: email(str) Returns: user_obj(dict) """ LOG.info("Deleting user %s", email) user_obj = self.user_collection.delete_one({'_id': email}) ret...
[ "Delete", "a", "user", "from", "the", "database", "Args", ":", "email", "(", "str", ")", "Returns", ":", "user_obj", "(", "dict", ")" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/adapter/mongo/user.py#L86-L99
[ "def", "delete_user", "(", "self", ",", "email", ")", ":", "LOG", ".", "info", "(", "\"Deleting user %s\"", ",", "email", ")", "user_obj", "=", "self", ".", "user_collection", ".", "delete_one", "(", "{", "'_id'", ":", "email", "}", ")", "return", "user_...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
build_compound
Build a compound Args: compound(dict) Returns: compound_obj(dict) dict( # This must be the document_id for this variant variant = str, # required=True # This is the variant id display_name = str, # required combined_score = float, # requ...
scout/build/variant/compound.py
def build_compound(compound): """Build a compound Args: compound(dict) Returns: compound_obj(dict) dict( # This must be the document_id for this variant variant = str, # required=True # This is the variant id display_name = str, # required ...
def build_compound(compound): """Build a compound Args: compound(dict) Returns: compound_obj(dict) dict( # This must be the document_id for this variant variant = str, # required=True # This is the variant id display_name = str, # required ...
[ "Build", "a", "compound", "Args", ":", "compound", "(", "dict", ")", "Returns", ":", "compound_obj", "(", "dict", ")", "dict", "(", "#", "This", "must", "be", "the", "document_id", "for", "this", "variant", "variant", "=", "str", "#", "required", "=", ...
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/build/variant/compound.py#L2-L37
[ "def", "build_compound", "(", "compound", ")", ":", "compound_obj", "=", "dict", "(", "variant", "=", "compound", "[", "'variant'", "]", ",", "display_name", "=", "compound", "[", "'display_name'", "]", ",", "combined_score", "=", "float", "(", "compound", "...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
remote_static
Stream *large* static files with special requirements.
scout/server/blueprints/alignviewers/views.py
def remote_static(): """Stream *large* static files with special requirements.""" file_path = request.args.get('file') range_header = request.headers.get('Range', None) if not range_header and file_path.endswith('.bam'): return abort(500) new_resp = send_file_partial(file_path) return ...
def remote_static(): """Stream *large* static files with special requirements.""" file_path = request.args.get('file') range_header = request.headers.get('Range', None) if not range_header and file_path.endswith('.bam'): return abort(500) new_resp = send_file_partial(file_path) return ...
[ "Stream", "*", "large", "*", "static", "files", "with", "special", "requirements", "." ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/server/blueprints/alignviewers/views.py#L16-L25
[ "def", "remote_static", "(", ")", ":", "file_path", "=", "request", ".", "args", ".", "get", "(", "'file'", ")", "range_header", "=", "request", ".", "headers", ".", "get", "(", "'Range'", ",", "None", ")", "if", "not", "range_header", "and", "file_path"...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
pileup
Visualize BAM alignments.
scout/server/blueprints/alignviewers/views.py
def pileup(): """Visualize BAM alignments.""" vcf_file = request.args.get('vcf') bam_files = request.args.getlist('bam') bai_files = request.args.getlist('bai') samples = request.args.getlist('sample') alignments = [{'bam': bam, 'bai': bai, 'sample': sample} for bam, bai, sampl...
def pileup(): """Visualize BAM alignments.""" vcf_file = request.args.get('vcf') bam_files = request.args.getlist('bam') bai_files = request.args.getlist('bai') samples = request.args.getlist('sample') alignments = [{'bam': bam, 'bai': bai, 'sample': sample} for bam, bai, sampl...
[ "Visualize", "BAM", "alignments", "." ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/server/blueprints/alignviewers/views.py#L29-L64
[ "def", "pileup", "(", ")", ":", "vcf_file", "=", "request", ".", "args", ".", "get", "(", "'vcf'", ")", "bam_files", "=", "request", ".", "args", ".", "getlist", "(", "'bam'", ")", "bai_files", "=", "request", ".", "args", ".", "getlist", "(", "'bai'...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
igv
Visualize BAM alignments using igv.js (https://github.com/igvteam/igv.js)
scout/server/blueprints/alignviewers/views.py
def igv(): """Visualize BAM alignments using igv.js (https://github.com/igvteam/igv.js)""" chrom = request.args.get('contig') if chrom == 'MT': chrom = 'M' start = request.args.get('start') stop = request.args.get('stop') locus = "chr{0}:{1}-{2}".format(chrom,start,stop) LOG.debug(...
def igv(): """Visualize BAM alignments using igv.js (https://github.com/igvteam/igv.js)""" chrom = request.args.get('contig') if chrom == 'MT': chrom = 'M' start = request.args.get('start') stop = request.args.get('stop') locus = "chr{0}:{1}-{2}".format(chrom,start,stop) LOG.debug(...
[ "Visualize", "BAM", "alignments", "using", "igv", ".", "js", "(", "https", ":", "//", "github", ".", "com", "/", "igvteam", "/", "igv", ".", "js", ")" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/server/blueprints/alignviewers/views.py#L68-L147
[ "def", "igv", "(", ")", ":", "chrom", "=", "request", ".", "args", ".", "get", "(", "'contig'", ")", "if", "chrom", "==", "'MT'", ":", "chrom", "=", "'M'", "start", "=", "request", ".", "args", ".", "get", "(", "'start'", ")", "stop", "=", "reque...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
build_disease_term
Build a disease phenotype object Args: disease_info(dict): Dictionary with phenotype information alias_genes(dict): { <alias_symbol>: { 'true': hgnc_id or None, 'ids': [<hgnc_id>, ...]}} ...
scout/build/disease.py
def build_disease_term(disease_info, alias_genes={}): """Build a disease phenotype object Args: disease_info(dict): Dictionary with phenotype information alias_genes(dict): { <alias_symbol>: { 'true': hgnc_id or None, ...
def build_disease_term(disease_info, alias_genes={}): """Build a disease phenotype object Args: disease_info(dict): Dictionary with phenotype information alias_genes(dict): { <alias_symbol>: { 'true': hgnc_id or None, ...
[ "Build", "a", "disease", "phenotype", "object", "Args", ":", "disease_info", "(", "dict", ")", ":", "Dictionary", "with", "phenotype", "information", "alias_genes", "(", "dict", ")", ":", "{", "<alias_symbol", ">", ":", "{", "true", ":", "hgnc_id", "or", "...
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/build/disease.py#L7-L79
[ "def", "build_disease_term", "(", "disease_info", ",", "alias_genes", "=", "{", "}", ")", ":", "try", ":", "disease_nr", "=", "int", "(", "disease_info", "[", "'mim_number'", "]", ")", "except", "KeyError", ":", "raise", "KeyError", "(", "\"Diseases has to hav...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
load_exons
Load all the exons Transcript information is from ensembl. Check that the transcript that the exon belongs to exists in the database Args: adapter(MongoAdapter) exon_lines(iterable): iterable with ensembl exon lines build(str) ensembl_transcripts(dict): Existing ensembl...
scout/load/exon.py
def load_exons(adapter, exon_lines, build='37', ensembl_genes=None): """Load all the exons Transcript information is from ensembl. Check that the transcript that the exon belongs to exists in the database Args: adapter(MongoAdapter) exon_lines(iterable): iterable with ensembl exon ...
def load_exons(adapter, exon_lines, build='37', ensembl_genes=None): """Load all the exons Transcript information is from ensembl. Check that the transcript that the exon belongs to exists in the database Args: adapter(MongoAdapter) exon_lines(iterable): iterable with ensembl exon ...
[ "Load", "all", "the", "exons", "Transcript", "information", "is", "from", "ensembl", ".", "Check", "that", "the", "transcript", "that", "the", "exon", "belongs", "to", "exists", "in", "the", "database" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/load/exon.py#L15-L64
[ "def", "load_exons", "(", "adapter", ",", "exon_lines", ",", "build", "=", "'37'", ",", "ensembl_genes", "=", "None", ")", ":", "# Fetch all genes with ensemblid as keys", "ensembl_genes", "=", "ensembl_genes", "or", "adapter", ".", "ensembl_genes", "(", "build", ...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
parse_variant
Return a parsed variant Get all the necessary information to build a variant object Args: variant(cyvcf2.Variant) case(dict) variant_type(str): 'clinical' or 'research' rank_results_header(list) vep_header(list) individual_positions(dict): Explain what posit...
scout/parse/variant/variant.py
def parse_variant(variant, case, variant_type='clinical', rank_results_header=None, vep_header=None, individual_positions=None, category=None): """Return a parsed variant Get all the necessary information to build a variant object Args: variant(cyvcf2.Variant)...
def parse_variant(variant, case, variant_type='clinical', rank_results_header=None, vep_header=None, individual_positions=None, category=None): """Return a parsed variant Get all the necessary information to build a variant object Args: variant(cyvcf2.Variant)...
[ "Return", "a", "parsed", "variant" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/parse/variant/variant.py#L26-L297
[ "def", "parse_variant", "(", "variant", ",", "case", ",", "variant_type", "=", "'clinical'", ",", "rank_results_header", "=", "None", ",", "vep_header", "=", "None", ",", "individual_positions", "=", "None", ",", "category", "=", "None", ")", ":", "# These are...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
compounds
Update all compounds for a case
scout/commands/update/compounds.py
def compounds(context, case_id): """ Update all compounds for a case """ adapter = context.obj['adapter'] LOG.info("Running scout update compounds") # Check if the case exists case_obj = adapter.case(case_id) if not case_obj: LOG.warning("Case %s could not be found", case_id...
def compounds(context, case_id): """ Update all compounds for a case """ adapter = context.obj['adapter'] LOG.info("Running scout update compounds") # Check if the case exists case_obj = adapter.case(case_id) if not case_obj: LOG.warning("Case %s could not be found", case_id...
[ "Update", "all", "compounds", "for", "a", "case" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/commands/update/compounds.py#L12-L29
[ "def", "compounds", "(", "context", ",", "case_id", ")", ":", "adapter", "=", "context", ".", "obj", "[", "'adapter'", "]", "LOG", ".", "info", "(", "\"Running scout update compounds\"", ")", "# Check if the case exists", "case_obj", "=", "adapter", ".", "case",...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
add_gene_links
Update a gene object with links Args: gene_obj(dict) build(int) Returns: gene_obj(dict): gene_obj updated with many links
scout/server/links.py
def add_gene_links(gene_obj, build=37): """Update a gene object with links Args: gene_obj(dict) build(int) Returns: gene_obj(dict): gene_obj updated with many links """ try: build = int(build) except ValueError: build = 37 # Add links that use the hg...
def add_gene_links(gene_obj, build=37): """Update a gene object with links Args: gene_obj(dict) build(int) Returns: gene_obj(dict): gene_obj updated with many links """ try: build = int(build) except ValueError: build = 37 # Add links that use the hg...
[ "Update", "a", "gene", "object", "with", "links" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/server/links.py#L3-L49
[ "def", "add_gene_links", "(", "gene_obj", ",", "build", "=", "37", ")", ":", "try", ":", "build", "=", "int", "(", "build", ")", "except", "ValueError", ":", "build", "=", "37", "# Add links that use the hgnc_id", "hgnc_id", "=", "gene_obj", "[", "'hgnc_id'"...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
hgnc
Query the hgnc aliases
scout/commands/query/query_command.py
def hgnc(ctx, hgnc_symbol, hgnc_id, build): """ Query the hgnc aliases """ adapter = ctx.obj['adapter'] if not (hgnc_symbol or hgnc_id): log.warning("Please provide a hgnc symbol or hgnc id") ctx.abort() if hgnc_id: result = adapter.hgnc_gene(hgnc_id, build=build) ...
def hgnc(ctx, hgnc_symbol, hgnc_id, build): """ Query the hgnc aliases """ adapter = ctx.obj['adapter'] if not (hgnc_symbol or hgnc_id): log.warning("Please provide a hgnc symbol or hgnc id") ctx.abort() if hgnc_id: result = adapter.hgnc_gene(hgnc_id, build=build) ...
[ "Query", "the", "hgnc", "aliases" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/commands/query/query_command.py#L21-L52
[ "def", "hgnc", "(", "ctx", ",", "hgnc_symbol", ",", "hgnc_id", ",", "build", ")", ":", "adapter", "=", "ctx", ".", "obj", "[", "'adapter'", "]", "if", "not", "(", "hgnc_symbol", "or", "hgnc_id", ")", ":", "log", ".", "warning", "(", "\"Please provide a...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
parse_hgnc_line
Parse an hgnc formated line Args: line(list): A list with hgnc gene info header(list): A list with the header info Returns: hgnc_info(dict): A dictionary with the relevant info
scout/parse/hgnc.py
def parse_hgnc_line(line, header): """Parse an hgnc formated line Args: line(list): A list with hgnc gene info header(list): A list with the header info Returns: hgnc_info(dict): A dictionary with the relevant info """ hgnc_gene = {} line = line.rstr...
def parse_hgnc_line(line, header): """Parse an hgnc formated line Args: line(list): A list with hgnc gene info header(list): A list with the header info Returns: hgnc_info(dict): A dictionary with the relevant info """ hgnc_gene = {} line = line.rstr...
[ "Parse", "an", "hgnc", "formated", "line" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/parse/hgnc.py#L7-L85
[ "def", "parse_hgnc_line", "(", "line", ",", "header", ")", ":", "hgnc_gene", "=", "{", "}", "line", "=", "line", ".", "rstrip", "(", ")", ".", "split", "(", "'\\t'", ")", "raw_info", "=", "dict", "(", "zip", "(", "header", ",", "line", ")", ")", ...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
parse_hgnc_genes
Parse lines with hgnc formated genes This is designed to take a dump with genes from HGNC. This is downloaded from: ftp://ftp.ebi.ac.uk/pub/databases/genenames/new/tsv/hgnc_complete_set.txt Args: lines(iterable(str)): An iterable with HGNC formated genes Yields: ...
scout/parse/hgnc.py
def parse_hgnc_genes(lines): """Parse lines with hgnc formated genes This is designed to take a dump with genes from HGNC. This is downloaded from: ftp://ftp.ebi.ac.uk/pub/databases/genenames/new/tsv/hgnc_complete_set.txt Args: lines(iterable(str)): An iterable with HGN...
def parse_hgnc_genes(lines): """Parse lines with hgnc formated genes This is designed to take a dump with genes from HGNC. This is downloaded from: ftp://ftp.ebi.ac.uk/pub/databases/genenames/new/tsv/hgnc_complete_set.txt Args: lines(iterable(str)): An iterable with HGN...
[ "Parse", "lines", "with", "hgnc", "formated", "genes" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/parse/hgnc.py#L88-L108
[ "def", "parse_hgnc_genes", "(", "lines", ")", ":", "header", "=", "[", "]", "logger", ".", "info", "(", "\"Parsing hgnc genes...\"", ")", "for", "index", ",", "line", "in", "enumerate", "(", "lines", ")", ":", "if", "index", "==", "0", ":", "header", "...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
ClinVarHandler.create_submission
Create an open clinvar submission for a user and an institute Args: user_id(str): a user ID institute_id(str): an institute ID returns: submission(obj): an open clinvar submission object
scout/adapter/mongo/clinvar.py
def create_submission(self, user_id, institute_id): """Create an open clinvar submission for a user and an institute Args: user_id(str): a user ID institute_id(str): an institute ID returns: submission(obj): an open clinvar submission object...
def create_submission(self, user_id, institute_id): """Create an open clinvar submission for a user and an institute Args: user_id(str): a user ID institute_id(str): an institute ID returns: submission(obj): an open clinvar submission object...
[ "Create", "an", "open", "clinvar", "submission", "for", "a", "user", "and", "an", "institute", "Args", ":", "user_id", "(", "str", ")", ":", "a", "user", "ID", "institute_id", "(", "str", ")", ":", "an", "institute", "ID" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/adapter/mongo/clinvar.py#L13-L31
[ "def", "create_submission", "(", "self", ",", "user_id", ",", "institute_id", ")", ":", "submission_obj", "=", "{", "'status'", ":", "'open'", ",", "'created_at'", ":", "datetime", ".", "now", "(", ")", ",", "'user_id'", ":", "user_id", ",", "'institute_id'"...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
ClinVarHandler.delete_submission
Deletes a Clinvar submission object, along with all associated clinvar objects (variants and casedata) Args: submission_id(str): the ID of the submission to be deleted Returns: deleted_objects(int): the number of associated objects removed (variants and/or cased...
scout/adapter/mongo/clinvar.py
def delete_submission(self, submission_id): """Deletes a Clinvar submission object, along with all associated clinvar objects (variants and casedata) Args: submission_id(str): the ID of the submission to be deleted Returns: deleted_objects(int): the numb...
def delete_submission(self, submission_id): """Deletes a Clinvar submission object, along with all associated clinvar objects (variants and casedata) Args: submission_id(str): the ID of the submission to be deleted Returns: deleted_objects(int): the numb...
[ "Deletes", "a", "Clinvar", "submission", "object", "along", "with", "all", "associated", "clinvar", "objects", "(", "variants", "and", "casedata", ")" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/adapter/mongo/clinvar.py#L34-L68
[ "def", "delete_submission", "(", "self", ",", "submission_id", ")", ":", "LOG", ".", "info", "(", "\"Deleting clinvar submission %s\"", ",", "submission_id", ")", "submission_obj", "=", "self", ".", "clinvar_submission_collection", ".", "find_one", "(", "{", "'_id'"...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
ClinVarHandler.get_open_clinvar_submission
Retrieve the database id of an open clinvar submission for a user and institute, if none is available then create a new submission and return it Args: user_id(str): a user ID institute_id(str): an institute ID Returns: submission(obj) : ...
scout/adapter/mongo/clinvar.py
def get_open_clinvar_submission(self, user_id, institute_id): """Retrieve the database id of an open clinvar submission for a user and institute, if none is available then create a new submission and return it Args: user_id(str): a user ID institute_id(str)...
def get_open_clinvar_submission(self, user_id, institute_id): """Retrieve the database id of an open clinvar submission for a user and institute, if none is available then create a new submission and return it Args: user_id(str): a user ID institute_id(str)...
[ "Retrieve", "the", "database", "id", "of", "an", "open", "clinvar", "submission", "for", "a", "user", "and", "institute", "if", "none", "is", "available", "then", "create", "a", "new", "submission", "and", "return", "it" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/adapter/mongo/clinvar.py#L71-L92
[ "def", "get_open_clinvar_submission", "(", "self", ",", "user_id", ",", "institute_id", ")", ":", "LOG", ".", "info", "(", "\"Retrieving an open clinvar submission for user '%s' and institute %s\"", ",", "user_id", ",", "institute_id", ")", "query", "=", "dict", "(", ...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
ClinVarHandler.update_clinvar_id
saves an official clinvar submission ID in a clinvar submission object Args: clinvar_id(str): a string with a format: SUB[0-9]. It is obtained from clinvar portal when starting a new submission submission_id(str): submission_id(str) : id of the submission to be updated ...
scout/adapter/mongo/clinvar.py
def update_clinvar_id(self, clinvar_id, submission_id ): """saves an official clinvar submission ID in a clinvar submission object Args: clinvar_id(str): a string with a format: SUB[0-9]. It is obtained from clinvar portal when starting a new submission submission_id...
def update_clinvar_id(self, clinvar_id, submission_id ): """saves an official clinvar submission ID in a clinvar submission object Args: clinvar_id(str): a string with a format: SUB[0-9]. It is obtained from clinvar portal when starting a new submission submission_id...
[ "saves", "an", "official", "clinvar", "submission", "ID", "in", "a", "clinvar", "submission", "object" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/adapter/mongo/clinvar.py#L95-L106
[ "def", "update_clinvar_id", "(", "self", ",", "clinvar_id", ",", "submission_id", ")", ":", "updated_submission", "=", "self", ".", "clinvar_submission_collection", ".", "find_one_and_update", "(", "{", "'_id'", ":", "ObjectId", "(", "submission_id", ")", "}", ","...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
ClinVarHandler.get_clinvar_id
Returns the official Clinvar submission ID for a submission object Args: submission_id(str): submission_id(str) : id of the submission Returns: clinvar_subm_id(str): a string with a format: SUB[0-9]. It is obtained from clinvar portal when starting a new submiss...
scout/adapter/mongo/clinvar.py
def get_clinvar_id(self, submission_id): """Returns the official Clinvar submission ID for a submission object Args: submission_id(str): submission_id(str) : id of the submission Returns: clinvar_subm_id(str): a string with a format: SUB[0-9]. It is obta...
def get_clinvar_id(self, submission_id): """Returns the official Clinvar submission ID for a submission object Args: submission_id(str): submission_id(str) : id of the submission Returns: clinvar_subm_id(str): a string with a format: SUB[0-9]. It is obta...
[ "Returns", "the", "official", "Clinvar", "submission", "ID", "for", "a", "submission", "object" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/adapter/mongo/clinvar.py#L109-L121
[ "def", "get_clinvar_id", "(", "self", ",", "submission_id", ")", ":", "submission_obj", "=", "self", ".", "clinvar_submission_collection", ".", "find_one", "(", "{", "'_id'", ":", "ObjectId", "(", "submission_id", ")", "}", ")", "clinvar_subm_id", "=", "submissi...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
ClinVarHandler.add_to_submission
Adds submission_objects to clinvar collection and update the coresponding submission object with their id Args: submission_id(str) : id of the submission to be updated submission_objects(tuple): a tuple of 2 elements coresponding to a list of variants and a list of case data...
scout/adapter/mongo/clinvar.py
def add_to_submission(self, submission_id, submission_objects): """Adds submission_objects to clinvar collection and update the coresponding submission object with their id Args: submission_id(str) : id of the submission to be updated submission_objects(tuple): a tup...
def add_to_submission(self, submission_id, submission_objects): """Adds submission_objects to clinvar collection and update the coresponding submission object with their id Args: submission_id(str) : id of the submission to be updated submission_objects(tuple): a tup...
[ "Adds", "submission_objects", "to", "clinvar", "collection", "and", "update", "the", "coresponding", "submission", "object", "with", "their", "id" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/adapter/mongo/clinvar.py#L124-L157
[ "def", "add_to_submission", "(", "self", ",", "submission_id", ",", "submission_objects", ")", ":", "LOG", ".", "info", "(", "\"Adding new variants and case data to clinvar submission '%s'\"", ",", "submission_id", ")", "# Insert variant submission_objects into clinvar collection...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
ClinVarHandler.update_clinvar_submission_status
Set a clinvar submission ID to 'closed' Args: submission_id(str): the ID of the clinvar submission to close Return updated_submission(obj): the submission object with a 'closed' status
scout/adapter/mongo/clinvar.py
def update_clinvar_submission_status(self, user_id, submission_id, status): """Set a clinvar submission ID to 'closed' Args: submission_id(str): the ID of the clinvar submission to close Return updated_submission(obj): the submission object with a 'close...
def update_clinvar_submission_status(self, user_id, submission_id, status): """Set a clinvar submission ID to 'closed' Args: submission_id(str): the ID of the clinvar submission to close Return updated_submission(obj): the submission object with a 'close...
[ "Set", "a", "clinvar", "submission", "ID", "to", "closed" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/adapter/mongo/clinvar.py#L160-L188
[ "def", "update_clinvar_submission_status", "(", "self", ",", "user_id", ",", "submission_id", ",", "status", ")", ":", "LOG", ".", "info", "(", "'closing clinvar submission \"%s\"'", ",", "submission_id", ")", "if", "status", "==", "'open'", ":", "# just close the s...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
ClinVarHandler.clinvar_submissions
Collect all open and closed clinvar submission created by a user for an institute Args: user_id(str): a user ID institute_id(str): an institute ID Returns: submissions(list): a list of clinvar submission objects
scout/adapter/mongo/clinvar.py
def clinvar_submissions(self, user_id, institute_id): """Collect all open and closed clinvar submission created by a user for an institute Args: user_id(str): a user ID institute_id(str): an institute ID Returns: submissions(list): a list...
def clinvar_submissions(self, user_id, institute_id): """Collect all open and closed clinvar submission created by a user for an institute Args: user_id(str): a user ID institute_id(str): an institute ID Returns: submissions(list): a list...
[ "Collect", "all", "open", "and", "closed", "clinvar", "submission", "created", "by", "a", "user", "for", "an", "institute" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/adapter/mongo/clinvar.py#L191-L226
[ "def", "clinvar_submissions", "(", "self", ",", "user_id", ",", "institute_id", ")", ":", "LOG", ".", "info", "(", "\"Retrieving all clinvar submissions for user '%s', institute '%s'\"", ",", "user_id", ",", "institute_id", ")", "# get first all submission objects", "query"...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
ClinVarHandler.clinvar_objs
Collects a list of objects from the clinvar collection (variants of case data) as specified by the key_id in the clinvar submission Args: submission_id(str): the _id key of a clinvar submission key_id(str) : either 'variant_data' or 'case_data'. It's a key in a clinvar_submi...
scout/adapter/mongo/clinvar.py
def clinvar_objs(self, submission_id, key_id): """Collects a list of objects from the clinvar collection (variants of case data) as specified by the key_id in the clinvar submission Args: submission_id(str): the _id key of a clinvar submission key_id(str) : either 'v...
def clinvar_objs(self, submission_id, key_id): """Collects a list of objects from the clinvar collection (variants of case data) as specified by the key_id in the clinvar submission Args: submission_id(str): the _id key of a clinvar submission key_id(str) : either 'v...
[ "Collects", "a", "list", "of", "objects", "from", "the", "clinvar", "collection", "(", "variants", "of", "case", "data", ")", "as", "specified", "by", "the", "key_id", "in", "the", "clinvar", "submission" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/adapter/mongo/clinvar.py#L229-L250
[ "def", "clinvar_objs", "(", "self", ",", "submission_id", ",", "key_id", ")", ":", "# Get a submission object", "submission", "=", "self", ".", "clinvar_submission_collection", ".", "find_one", "(", "{", "'_id'", ":", "ObjectId", "(", "submission_id", ")", "}", ...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
ClinVarHandler.delete_clinvar_object
Remove a variant object from clinvar database and update the relative submission object Args: object_id(str) : the id of an object to remove from clinvar_collection database collection (a variant of a case) object_type(str) : either 'variant_data' or 'case_data'. It's a key ...
scout/adapter/mongo/clinvar.py
def delete_clinvar_object(self, object_id, object_type, submission_id): """Remove a variant object from clinvar database and update the relative submission object Args: object_id(str) : the id of an object to remove from clinvar_collection database collection (a variant of a case) ...
def delete_clinvar_object(self, object_id, object_type, submission_id): """Remove a variant object from clinvar database and update the relative submission object Args: object_id(str) : the id of an object to remove from clinvar_collection database collection (a variant of a case) ...
[ "Remove", "a", "variant", "object", "from", "clinvar", "database", "and", "update", "the", "relative", "submission", "object" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/adapter/mongo/clinvar.py#L253-L298
[ "def", "delete_clinvar_object", "(", "self", ",", "object_id", ",", "object_type", ",", "submission_id", ")", ":", "LOG", ".", "info", "(", "\"Deleting clinvar object %s (%s)\"", ",", "object_id", ",", "object_type", ")", "# If it's a variant object to be removed:", "# ...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
ClinVarHandler.case_to_clinVars
Get all variants included in clinvar submissions for a case Args: case_id(str): a case _id Returns: submission_variants(dict): keys are variant ids and values are variant submission objects
scout/adapter/mongo/clinvar.py
def case_to_clinVars(self, case_id): """Get all variants included in clinvar submissions for a case Args: case_id(str): a case _id Returns: submission_variants(dict): keys are variant ids and values are variant submission objects """ query = dict(case_i...
def case_to_clinVars(self, case_id): """Get all variants included in clinvar submissions for a case Args: case_id(str): a case _id Returns: submission_variants(dict): keys are variant ids and values are variant submission objects """ query = dict(case_i...
[ "Get", "all", "variants", "included", "in", "clinvar", "submissions", "for", "a", "case" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/adapter/mongo/clinvar.py#L301-L317
[ "def", "case_to_clinVars", "(", "self", ",", "case_id", ")", ":", "query", "=", "dict", "(", "case_id", "=", "case_id", ",", "csv_type", "=", "'variant'", ")", "clinvar_objs", "=", "list", "(", "self", ".", "clinvar_collection", ".", "find", "(", "query", ...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
parse_hpo_phenotype
Parse hpo phenotype Args: hpo_line(str): A iterable with hpo phenotype lines Yields: hpo_info(dict)
scout/parse/hpo.py
def parse_hpo_phenotype(hpo_line): """Parse hpo phenotype Args: hpo_line(str): A iterable with hpo phenotype lines Yields: hpo_info(dict) """ hpo_line = hpo_line.rstrip().split('\t') hpo_info = {} hpo_info['hpo_id'] = hpo_line[0] hpo_info['descri...
def parse_hpo_phenotype(hpo_line): """Parse hpo phenotype Args: hpo_line(str): A iterable with hpo phenotype lines Yields: hpo_info(dict) """ hpo_line = hpo_line.rstrip().split('\t') hpo_info = {} hpo_info['hpo_id'] = hpo_line[0] hpo_info['descri...
[ "Parse", "hpo", "phenotype", "Args", ":", "hpo_line", "(", "str", ")", ":", "A", "iterable", "with", "hpo", "phenotype", "lines", "Yields", ":", "hpo_info", "(", "dict", ")" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/parse/hpo.py#L6-L21
[ "def", "parse_hpo_phenotype", "(", "hpo_line", ")", ":", "hpo_line", "=", "hpo_line", ".", "rstrip", "(", ")", ".", "split", "(", "'\\t'", ")", "hpo_info", "=", "{", "}", "hpo_info", "[", "'hpo_id'", "]", "=", "hpo_line", "[", "0", "]", "hpo_info", "["...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
parse_hpo_gene
Parse hpo gene information Args: hpo_line(str): A iterable with hpo phenotype lines Yields: hpo_info(dict)
scout/parse/hpo.py
def parse_hpo_gene(hpo_line): """Parse hpo gene information Args: hpo_line(str): A iterable with hpo phenotype lines Yields: hpo_info(dict) """ if not len(hpo_line) > 3: return {} hpo_line = hpo_line.rstrip().split('\t') hpo_info = {} hpo...
def parse_hpo_gene(hpo_line): """Parse hpo gene information Args: hpo_line(str): A iterable with hpo phenotype lines Yields: hpo_info(dict) """ if not len(hpo_line) > 3: return {} hpo_line = hpo_line.rstrip().split('\t') hpo_info = {} hpo...
[ "Parse", "hpo", "gene", "information", "Args", ":", "hpo_line", "(", "str", ")", ":", "A", "iterable", "with", "hpo", "phenotype", "lines", "Yields", ":", "hpo_info", "(", "dict", ")" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/parse/hpo.py#L23-L40
[ "def", "parse_hpo_gene", "(", "hpo_line", ")", ":", "if", "not", "len", "(", "hpo_line", ")", ">", "3", ":", "return", "{", "}", "hpo_line", "=", "hpo_line", ".", "rstrip", "(", ")", ".", "split", "(", "'\\t'", ")", "hpo_info", "=", "{", "}", "hpo_...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
parse_hpo_disease
Parse hpo disease line Args: hpo_line(str)
scout/parse/hpo.py
def parse_hpo_disease(hpo_line): """Parse hpo disease line Args: hpo_line(str) """ hpo_line = hpo_line.rstrip().split('\t') hpo_info = {} disease = hpo_line[0].split(':') hpo_info['source'] = disease[0] hpo_info['disease_nr'] = int(disease[1]) hpo_info['hgnc...
def parse_hpo_disease(hpo_line): """Parse hpo disease line Args: hpo_line(str) """ hpo_line = hpo_line.rstrip().split('\t') hpo_info = {} disease = hpo_line[0].split(':') hpo_info['source'] = disease[0] hpo_info['disease_nr'] = int(disease[1]) hpo_info['hgnc...
[ "Parse", "hpo", "disease", "line", "Args", ":", "hpo_line", "(", "str", ")" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/parse/hpo.py#L42-L64
[ "def", "parse_hpo_disease", "(", "hpo_line", ")", ":", "hpo_line", "=", "hpo_line", ".", "rstrip", "(", ")", ".", "split", "(", "'\\t'", ")", "hpo_info", "=", "{", "}", "disease", "=", "hpo_line", "[", "0", "]", ".", "split", "(", "':'", ")", "hpo_in...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
parse_hpo_phenotypes
Parse hpo phenotypes Group the genes that a phenotype is associated to in 'genes' Args: hpo_lines(iterable(str)): A file handle to the hpo phenotypes file Returns: hpo_terms(dict): A dictionary with hpo_ids as keys and terms as values { <hpo_id>: {...
scout/parse/hpo.py
def parse_hpo_phenotypes(hpo_lines): """Parse hpo phenotypes Group the genes that a phenotype is associated to in 'genes' Args: hpo_lines(iterable(str)): A file handle to the hpo phenotypes file Returns: hpo_terms(dict): A dictionary with hpo_ids as keys and terms as v...
def parse_hpo_phenotypes(hpo_lines): """Parse hpo phenotypes Group the genes that a phenotype is associated to in 'genes' Args: hpo_lines(iterable(str)): A file handle to the hpo phenotypes file Returns: hpo_terms(dict): A dictionary with hpo_ids as keys and terms as v...
[ "Parse", "hpo", "phenotypes", "Group", "the", "genes", "that", "a", "phenotype", "is", "associated", "to", "in", "genes", "Args", ":", "hpo_lines", "(", "iterable", "(", "str", "))", ":", "A", "file", "handle", "to", "the", "hpo", "phenotypes", "file", "...
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/parse/hpo.py#L66-L101
[ "def", "parse_hpo_phenotypes", "(", "hpo_lines", ")", ":", "hpo_terms", "=", "{", "}", "LOG", ".", "info", "(", "\"Parsing hpo phenotypes...\"", ")", "for", "index", ",", "line", "in", "enumerate", "(", "hpo_lines", ")", ":", "if", "index", ">", "0", "and"...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
parse_hpo_diseases
Parse hpo disease phenotypes Args: hpo_lines(iterable(str)) Returns: diseases(dict): A dictionary with mim numbers as keys
scout/parse/hpo.py
def parse_hpo_diseases(hpo_lines): """Parse hpo disease phenotypes Args: hpo_lines(iterable(str)) Returns: diseases(dict): A dictionary with mim numbers as keys """ diseases = {} LOG.info("Parsing hpo diseases...") for index, line in enumerate(hp...
def parse_hpo_diseases(hpo_lines): """Parse hpo disease phenotypes Args: hpo_lines(iterable(str)) Returns: diseases(dict): A dictionary with mim numbers as keys """ diseases = {} LOG.info("Parsing hpo diseases...") for index, line in enumerate(hp...
[ "Parse", "hpo", "disease", "phenotypes", "Args", ":", "hpo_lines", "(", "iterable", "(", "str", "))", "Returns", ":", "diseases", "(", "dict", ")", ":", "A", "dictionary", "with", "mim", "numbers", "as", "keys" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/parse/hpo.py#L103-L146
[ "def", "parse_hpo_diseases", "(", "hpo_lines", ")", ":", "diseases", "=", "{", "}", "LOG", ".", "info", "(", "\"Parsing hpo diseases...\"", ")", "for", "index", ",", "line", "in", "enumerate", "(", "hpo_lines", ")", ":", "# First line is a header", "if", "inde...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
parse_hpo_to_genes
Parse the map from hpo term to hgnc symbol Args: lines(iterable(str)): Yields: hpo_to_gene(dict): A dictionary with information on how a term map to a hgnc symbol
scout/parse/hpo.py
def parse_hpo_to_genes(hpo_lines): """Parse the map from hpo term to hgnc symbol Args: lines(iterable(str)): Yields: hpo_to_gene(dict): A dictionary with information on how a term map to a hgnc symbol """ for line in hpo_lines: if line.startswith('#') or len(line) <...
def parse_hpo_to_genes(hpo_lines): """Parse the map from hpo term to hgnc symbol Args: lines(iterable(str)): Yields: hpo_to_gene(dict): A dictionary with information on how a term map to a hgnc symbol """ for line in hpo_lines: if line.startswith('#') or len(line) <...
[ "Parse", "the", "map", "from", "hpo", "term", "to", "hgnc", "symbol", "Args", ":", "lines", "(", "iterable", "(", "str", "))", ":", "Yields", ":", "hpo_to_gene", "(", "dict", ")", ":", "A", "dictionary", "with", "information", "on", "how", "a", "term",...
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/parse/hpo.py#L149-L168
[ "def", "parse_hpo_to_genes", "(", "hpo_lines", ")", ":", "for", "line", "in", "hpo_lines", ":", "if", "line", ".", "startswith", "(", "'#'", ")", "or", "len", "(", "line", ")", "<", "1", ":", "continue", "line", "=", "line", ".", "rstrip", "(", ")", ...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
parse_hpo_genes
Parse HPO gene information Args: hpo_lines(iterable(str)) Returns: diseases(dict): A dictionary with hgnc symbols as keys
scout/parse/hpo.py
def parse_hpo_genes(hpo_lines): """Parse HPO gene information Args: hpo_lines(iterable(str)) Returns: diseases(dict): A dictionary with hgnc symbols as keys """ LOG.info("Parsing HPO genes ...") genes = {} for index, line in enumerate(hpo_lines):...
def parse_hpo_genes(hpo_lines): """Parse HPO gene information Args: hpo_lines(iterable(str)) Returns: diseases(dict): A dictionary with hgnc symbols as keys """ LOG.info("Parsing HPO genes ...") genes = {} for index, line in enumerate(hpo_lines):...
[ "Parse", "HPO", "gene", "information", "Args", ":", "hpo_lines", "(", "iterable", "(", "str", "))", "Returns", ":", "diseases", "(", "dict", ")", ":", "A", "dictionary", "with", "hgnc", "symbols", "as", "keys" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/parse/hpo.py#L172-L216
[ "def", "parse_hpo_genes", "(", "hpo_lines", ")", ":", "LOG", ".", "info", "(", "\"Parsing HPO genes ...\"", ")", "genes", "=", "{", "}", "for", "index", ",", "line", "in", "enumerate", "(", "hpo_lines", ")", ":", "# First line is header", "if", "index", "=="...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
get_incomplete_penetrance_genes
Get a set with all genes that have incomplete penetrance according to HPO Args: hpo_lines(iterable(str)) Returns: incomplete_penetrance_genes(set): A set with the hgnc symbols of all genes with incomplete penetrance
scout/parse/hpo.py
def get_incomplete_penetrance_genes(hpo_lines): """Get a set with all genes that have incomplete penetrance according to HPO Args: hpo_lines(iterable(str)) Returns: incomplete_penetrance_genes(set): A set with the hgnc symbols of all genes...
def get_incomplete_penetrance_genes(hpo_lines): """Get a set with all genes that have incomplete penetrance according to HPO Args: hpo_lines(iterable(str)) Returns: incomplete_penetrance_genes(set): A set with the hgnc symbols of all genes...
[ "Get", "a", "set", "with", "all", "genes", "that", "have", "incomplete", "penetrance", "according", "to", "HPO", "Args", ":", "hpo_lines", "(", "iterable", "(", "str", "))", "Returns", ":", "incomplete_penetrance_genes", "(", "set", ")", ":", "A", "set", "...
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/parse/hpo.py#L219-L235
[ "def", "get_incomplete_penetrance_genes", "(", "hpo_lines", ")", ":", "genes", "=", "parse_hpo_genes", "(", "hpo_lines", ")", "incomplete_penetrance_genes", "=", "set", "(", ")", "for", "hgnc_symbol", "in", "genes", ":", "if", "genes", "[", "hgnc_symbol", "]", "...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
parse_hpo_obo
Parse a .obo formated hpo line
scout/parse/hpo.py
def parse_hpo_obo(hpo_lines): """Parse a .obo formated hpo line""" term = {} for line in hpo_lines: if len(line) == 0: continue line = line.rstrip() # New term starts with [Term] if line == '[Term]': if term: yield term term...
def parse_hpo_obo(hpo_lines): """Parse a .obo formated hpo line""" term = {} for line in hpo_lines: if len(line) == 0: continue line = line.rstrip() # New term starts with [Term] if line == '[Term]': if term: yield term term...
[ "Parse", "a", ".", "obo", "formated", "hpo", "line" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/parse/hpo.py#L237-L267
[ "def", "parse_hpo_obo", "(", "hpo_lines", ")", ":", "term", "=", "{", "}", "for", "line", "in", "hpo_lines", ":", "if", "len", "(", "line", ")", "==", "0", ":", "continue", "line", "=", "line", ".", "rstrip", "(", ")", "# New term starts with [Term]", ...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
genes
Render seach box for genes.
scout/server/blueprints/genes/views.py
def genes(): """Render seach box for genes.""" query = request.args.get('query', '') if '|' in query: hgnc_id = int(query.split(' | ', 1)[0]) return redirect(url_for('.gene', hgnc_id=hgnc_id)) gene_q = store.all_genes().limit(20) return dict(genes=gene_q)
def genes(): """Render seach box for genes.""" query = request.args.get('query', '') if '|' in query: hgnc_id = int(query.split(' | ', 1)[0]) return redirect(url_for('.gene', hgnc_id=hgnc_id)) gene_q = store.all_genes().limit(20) return dict(genes=gene_q)
[ "Render", "seach", "box", "for", "genes", "." ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/server/blueprints/genes/views.py#L13-L20
[ "def", "genes", "(", ")", ":", "query", "=", "request", ".", "args", ".", "get", "(", "'query'", ",", "''", ")", "if", "'|'", "in", "query", ":", "hgnc_id", "=", "int", "(", "query", ".", "split", "(", "' | '", ",", "1", ")", "[", "0", "]", "...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
gene
Render information about a gene.
scout/server/blueprints/genes/views.py
def gene(hgnc_id=None, hgnc_symbol=None): """Render information about a gene.""" if hgnc_symbol: query = store.hgnc_genes(hgnc_symbol) if query.count() == 1: hgnc_id = query.first()['hgnc_id'] else: return redirect(url_for('.genes', query=hgnc_symbol)) try: ...
def gene(hgnc_id=None, hgnc_symbol=None): """Render information about a gene.""" if hgnc_symbol: query = store.hgnc_genes(hgnc_symbol) if query.count() == 1: hgnc_id = query.first()['hgnc_id'] else: return redirect(url_for('.genes', query=hgnc_symbol)) try: ...
[ "Render", "information", "about", "a", "gene", "." ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/server/blueprints/genes/views.py#L26-L39
[ "def", "gene", "(", "hgnc_id", "=", "None", ",", "hgnc_symbol", "=", "None", ")", ":", "if", "hgnc_symbol", ":", "query", "=", "store", ".", "hgnc_genes", "(", "hgnc_symbol", ")", "if", "query", ".", "count", "(", ")", "==", "1", ":", "hgnc_id", "=",...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
api_genes
Return JSON data about genes.
scout/server/blueprints/genes/views.py
def api_genes(): """Return JSON data about genes.""" query = request.args.get('query') json_out = controllers.genes_to_json(store, query) return jsonify(json_out)
def api_genes(): """Return JSON data about genes.""" query = request.args.get('query') json_out = controllers.genes_to_json(store, query) return jsonify(json_out)
[ "Return", "JSON", "data", "about", "genes", "." ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/server/blueprints/genes/views.py#L44-L48
[ "def", "api_genes", "(", ")", ":", "query", "=", "request", ".", "args", ".", "get", "(", "'query'", ")", "json_out", "=", "controllers", ".", "genes_to_json", "(", "store", ",", "query", ")", "return", "jsonify", "(", "json_out", ")" ]
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
check_panels
Make sure that the gene panels exist in the database Also check if the default panels are defined in gene panels Args: adapter(MongoAdapter) panels(list(str)): A list with panel names Returns: panels_exists(bool)
scout/load/all.py
def check_panels(adapter, panels, default_panels=None): """Make sure that the gene panels exist in the database Also check if the default panels are defined in gene panels Args: adapter(MongoAdapter) panels(list(str)): A list with panel names Returns: pa...
def check_panels(adapter, panels, default_panels=None): """Make sure that the gene panels exist in the database Also check if the default panels are defined in gene panels Args: adapter(MongoAdapter) panels(list(str)): A list with panel names Returns: pa...
[ "Make", "sure", "that", "the", "gene", "panels", "exist", "in", "the", "database", "Also", "check", "if", "the", "default", "panels", "are", "defined", "in", "gene", "panels" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/load/all.py#L9-L30
[ "def", "check_panels", "(", "adapter", ",", "panels", ",", "default_panels", "=", "None", ")", ":", "default_panels", "=", "default_panels", "or", "[", "]", "panels_exist", "=", "True", "for", "panel", "in", "default_panels", ":", "if", "panel", "not", "in",...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
load_region
Load all variants in a region defined by a HGNC id Args: adapter (MongoAdapter) case_id (str): Case id hgnc_id (int): If all variants from a gene should be uploaded chrom (str): If variants from coordinates should be uploaded start (int): Start position for region en...
scout/load/all.py
def load_region(adapter, case_id, hgnc_id=None, chrom=None, start=None, end=None): """Load all variants in a region defined by a HGNC id Args: adapter (MongoAdapter) case_id (str): Case id hgnc_id (int): If all variants from a gene should be uploaded chrom (str): If variants fro...
def load_region(adapter, case_id, hgnc_id=None, chrom=None, start=None, end=None): """Load all variants in a region defined by a HGNC id Args: adapter (MongoAdapter) case_id (str): Case id hgnc_id (int): If all variants from a gene should be uploaded chrom (str): If variants fro...
[ "Load", "all", "variants", "in", "a", "region", "defined", "by", "a", "HGNC", "id" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/load/all.py#L33-L87
[ "def", "load_region", "(", "adapter", ",", "case_id", ",", "hgnc_id", "=", "None", ",", "chrom", "=", "None", ",", "start", "=", "None", ",", "end", "=", "None", ")", ":", "if", "hgnc_id", ":", "gene_obj", "=", "adapter", ".", "hgnc_gene", "(", "hgnc...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
load_scout
Load a new case from a Scout config. Args: adapter(MongoAdapter) config(dict): loading info ped(Iterable(str)): Pedigree ingformation update(bool): If existing case should be updated
scout/load/all.py
def load_scout(adapter, config, ped=None, update=False): """Load a new case from a Scout config. Args: adapter(MongoAdapter) config(dict): loading info ped(Iterable(str)): Pedigree ingformation update(bool): If existing case should be updated """ log...
def load_scout(adapter, config, ped=None, update=False): """Load a new case from a Scout config. Args: adapter(MongoAdapter) config(dict): loading info ped(Iterable(str)): Pedigree ingformation update(bool): If existing case should be updated """ log...
[ "Load", "a", "new", "case", "from", "a", "Scout", "config", "." ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/load/all.py#L90-L105
[ "def", "load_scout", "(", "adapter", ",", "config", ",", "ped", "=", "None", ",", "update", "=", "False", ")", ":", "log", ".", "info", "(", "\"Check that the panels exists\"", ")", "if", "not", "check_panels", "(", "adapter", ",", "config", ".", "get", ...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
templated
Template decorator. Ref: http://flask.pocoo.org/docs/patterns/viewdecorators/
scout/server/utils.py
def templated(template=None): """Template decorator. Ref: http://flask.pocoo.org/docs/patterns/viewdecorators/ """ def decorator(f): @wraps(f) def decorated_function(*args, **kwargs): template_name = template if template_name is None: template_nam...
def templated(template=None): """Template decorator. Ref: http://flask.pocoo.org/docs/patterns/viewdecorators/ """ def decorator(f): @wraps(f) def decorated_function(*args, **kwargs): template_name = template if template_name is None: template_nam...
[ "Template", "decorator", "." ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/server/utils.py#L7-L25
[ "def", "templated", "(", "template", "=", "None", ")", ":", "def", "decorator", "(", "f", ")", ":", "@", "wraps", "(", "f", ")", "def", "decorated_function", "(", "*", "args", ",", "*", "*", "kwargs", ")", ":", "template_name", "=", "template", "if",...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
institute_and_case
Fetch insitiute and case objects.
scout/server/utils.py
def institute_and_case(store, institute_id, case_name=None): """Fetch insitiute and case objects.""" institute_obj = store.institute(institute_id) if institute_obj is None and institute_id != 'favicon.ico': flash("Can't find institute: {}".format(institute_id), 'warning') return abort(404) ...
def institute_and_case(store, institute_id, case_name=None): """Fetch insitiute and case objects.""" institute_obj = store.institute(institute_id) if institute_obj is None and institute_id != 'favicon.ico': flash("Can't find institute: {}".format(institute_id), 'warning') return abort(404) ...
[ "Fetch", "insitiute", "and", "case", "objects", "." ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/server/utils.py#L33-L59
[ "def", "institute_and_case", "(", "store", ",", "institute_id", ",", "case_name", "=", "None", ")", ":", "institute_obj", "=", "store", ".", "institute", "(", "institute_id", ")", "if", "institute_obj", "is", "None", "and", "institute_id", "!=", "'favicon.ico'",...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
user_institutes
Preprocess institute objects.
scout/server/utils.py
def user_institutes(store, login_user): """Preprocess institute objects.""" if login_user.is_admin: institutes = store.institutes() else: institutes = [store.institute(inst_id) for inst_id in login_user.institutes] return institutes
def user_institutes(store, login_user): """Preprocess institute objects.""" if login_user.is_admin: institutes = store.institutes() else: institutes = [store.institute(inst_id) for inst_id in login_user.institutes] return institutes
[ "Preprocess", "institute", "objects", "." ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/server/utils.py#L62-L69
[ "def", "user_institutes", "(", "store", ",", "login_user", ")", ":", "if", "login_user", ".", "is_admin", ":", "institutes", "=", "store", ".", "institutes", "(", ")", "else", ":", "institutes", "=", "[", "store", ".", "institute", "(", "inst_id", ")", "...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
get_hgnc_id
Get the hgnc id for a gene The proprity order will be 1. if there is a hgnc id this one will be choosen 2. if the hgnc symbol matches a genes proper hgnc symbol 3. if the symbol ony matches aliases on several genes one will be choosen at random Args: gene...
scout/utils/hgnc_id.py
def get_hgnc_id(gene_info, adapter): """Get the hgnc id for a gene The proprity order will be 1. if there is a hgnc id this one will be choosen 2. if the hgnc symbol matches a genes proper hgnc symbol 3. if the symbol ony matches aliases on several genes one will be choos...
def get_hgnc_id(gene_info, adapter): """Get the hgnc id for a gene The proprity order will be 1. if there is a hgnc id this one will be choosen 2. if the hgnc symbol matches a genes proper hgnc symbol 3. if the symbol ony matches aliases on several genes one will be choos...
[ "Get", "the", "hgnc", "id", "for", "a", "gene" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/utils/hgnc_id.py#L1-L34
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90a551e2e1653a319e654c2405c2866f93d0ebb9
test
panel
Update a panel in the database
scout/commands/update/panel.py
def panel(context, panel, version, update_date, update_version): """ Update a panel in the database """ adapter = context.obj['adapter'] # Check that the panel exists panel_obj = adapter.gene_panel(panel, version=version) if not panel_obj: LOG.warning("Panel %s (version %s) could n...
def panel(context, panel, version, update_date, update_version): """ Update a panel in the database """ adapter = context.obj['adapter'] # Check that the panel exists panel_obj = adapter.gene_panel(panel, version=version) if not panel_obj: LOG.warning("Panel %s (version %s) could n...
[ "Update", "a", "panel", "in", "the", "database" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/commands/update/panel.py#L30-L57
[ "def", "panel", "(", "context", ",", "panel", ",", "version", ",", "update_date", ",", "update_version", ")", ":", "adapter", "=", "context", ".", "obj", "[", "'adapter'", "]", "# Check that the panel exists", "panel_obj", "=", "adapter", ".", "gene_panel", "(...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
diseases
Update disease terms in mongo database.
scout/commands/update/disease.py
def diseases(context, api_key): """ Update disease terms in mongo database. """ adapter = context.obj['adapter'] # Fetch the omim information api_key = api_key or context.obj.get('omim_api_key') if not api_key: LOG.warning("Please provide a omim api key to load the omim gene pan...
def diseases(context, api_key): """ Update disease terms in mongo database. """ adapter = context.obj['adapter'] # Fetch the omim information api_key = api_key or context.obj.get('omim_api_key') if not api_key: LOG.warning("Please provide a omim api key to load the omim gene pan...
[ "Update", "disease", "terms", "in", "mongo", "database", "." ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/commands/update/disease.py#L25-L52
[ "def", "diseases", "(", "context", ",", "api_key", ")", ":", "adapter", "=", "context", ".", "obj", "[", "'adapter'", "]", "# Fetch the omim information", "api_key", "=", "api_key", "or", "context", ".", "obj", ".", "get", "(", "'omim_api_key'", ")", "if", ...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
load_hpo
Load the hpo terms and hpo diseases into database Args: adapter(MongoAdapter) disease_lines(iterable(str)): These are the omim genemap2 information hpo_lines(iterable(str)) disease_lines(iterable(str)) hpo_gene_lines(iterable(str))
scout/load/hpo.py
def load_hpo(adapter, disease_lines, hpo_disease_lines=None, hpo_lines=None, hpo_gene_lines=None): """Load the hpo terms and hpo diseases into database Args: adapter(MongoAdapter) disease_lines(iterable(str)): These are the omim genemap2 information hpo_lines(iterable(str)) ...
def load_hpo(adapter, disease_lines, hpo_disease_lines=None, hpo_lines=None, hpo_gene_lines=None): """Load the hpo terms and hpo diseases into database Args: adapter(MongoAdapter) disease_lines(iterable(str)): These are the omim genemap2 information hpo_lines(iterable(str)) ...
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Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/load/hpo.py#L19-L46
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90a551e2e1653a319e654c2405c2866f93d0ebb9
test
load_hpo_terms
Load the hpo terms into the database Parse the hpo lines, build the objects and add them to the database Args: adapter(MongoAdapter) hpo_lines(iterable(str)) hpo_gene_lines(iterable(str))
scout/load/hpo.py
def load_hpo_terms(adapter, hpo_lines=None, hpo_gene_lines=None, alias_genes=None): """Load the hpo terms into the database Parse the hpo lines, build the objects and add them to the database Args: adapter(MongoAdapter) hpo_lines(iterable(str)) hpo_gene_lines(iterable(str))...
def load_hpo_terms(adapter, hpo_lines=None, hpo_gene_lines=None, alias_genes=None): """Load the hpo terms into the database Parse the hpo lines, build the objects and add them to the database Args: adapter(MongoAdapter) hpo_lines(iterable(str)) hpo_gene_lines(iterable(str))...
[ "Load", "the", "hpo", "terms", "into", "the", "database", "Parse", "the", "hpo", "lines", "build", "the", "objects", "and", "add", "them", "to", "the", "database", "Args", ":", "adapter", "(", "MongoAdapter", ")", "hpo_lines", "(", "iterable", "(", "str", ...
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/load/hpo.py#L48-L120
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90a551e2e1653a319e654c2405c2866f93d0ebb9
test
load_disease_terms
Load the omim phenotypes into the database Parse the phenotypes from genemap2.txt and find the associated hpo terms from ALL_SOURCES_ALL_FREQUENCIES_diseases_to_genes_to_phenotypes.txt. Args: adapter(MongoAdapter) genemap_lines(iterable(str)) genes(dict): Dictionary with all ge...
scout/load/hpo.py
def load_disease_terms(adapter, genemap_lines, genes=None, hpo_disease_lines=None): """Load the omim phenotypes into the database Parse the phenotypes from genemap2.txt and find the associated hpo terms from ALL_SOURCES_ALL_FREQUENCIES_diseases_to_genes_to_phenotypes.txt. Args: adapter(Mon...
def load_disease_terms(adapter, genemap_lines, genes=None, hpo_disease_lines=None): """Load the omim phenotypes into the database Parse the phenotypes from genemap2.txt and find the associated hpo terms from ALL_SOURCES_ALL_FREQUENCIES_diseases_to_genes_to_phenotypes.txt. Args: adapter(Mon...
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Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/load/hpo.py#L123-L164
[ "def", "load_disease_terms", "(", "adapter", ",", "genemap_lines", ",", "genes", "=", "None", ",", "hpo_disease_lines", "=", "None", ")", ":", "# Get a map with hgnc symbols to hgnc ids from scout", "if", "not", "genes", ":", "genes", "=", "adapter", ".", "genes_by_...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
parse_frequencies
Add the frequencies to a variant Frequencies are parsed either directly from keys in info fieds or from the transcripts is they are annotated there. Args: variant(cyvcf2.Variant): A parsed vcf variant transcripts(iterable(dict)): Parsed transcripts Returns: frequencies(dict): ...
scout/parse/variant/frequency.py
def parse_frequencies(variant, transcripts): """Add the frequencies to a variant Frequencies are parsed either directly from keys in info fieds or from the transcripts is they are annotated there. Args: variant(cyvcf2.Variant): A parsed vcf variant transcripts(iterable(dict)): Parsed t...
def parse_frequencies(variant, transcripts): """Add the frequencies to a variant Frequencies are parsed either directly from keys in info fieds or from the transcripts is they are annotated there. Args: variant(cyvcf2.Variant): A parsed vcf variant transcripts(iterable(dict)): Parsed t...
[ "Add", "the", "frequencies", "to", "a", "variant" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/parse/variant/frequency.py#L2-L95
[ "def", "parse_frequencies", "(", "variant", ",", "transcripts", ")", ":", "frequencies", "=", "{", "}", "# These lists could be extended...", "thousand_genomes_keys", "=", "[", "'1000GAF'", "]", "thousand_genomes_max_keys", "=", "[", "'1000G_MAX_AF'", "]", "exac_keys", ...
90a551e2e1653a319e654c2405c2866f93d0ebb9
test
parse_frequency
Parse any frequency from the info dict Args: variant(cyvcf2.Variant) info_key(str) Returns: frequency(float): or None if frequency does not exist
scout/parse/variant/frequency.py
def parse_frequency(variant, info_key): """Parse any frequency from the info dict Args: variant(cyvcf2.Variant) info_key(str) Returns: frequency(float): or None if frequency does not exist """ raw_annotation = variant.INFO.get(info_key) raw_annotation = None if raw_anno...
def parse_frequency(variant, info_key): """Parse any frequency from the info dict Args: variant(cyvcf2.Variant) info_key(str) Returns: frequency(float): or None if frequency does not exist """ raw_annotation = variant.INFO.get(info_key) raw_annotation = None if raw_anno...
[ "Parse", "any", "frequency", "from", "the", "info", "dict" ]
Clinical-Genomics/scout
python
https://github.com/Clinical-Genomics/scout/blob/90a551e2e1653a319e654c2405c2866f93d0ebb9/scout/parse/variant/frequency.py#L98-L111
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90a551e2e1653a319e654c2405c2866f93d0ebb9