Datasets:
Modality table: add Dtype column (raw/decoded types)
Browse files
README.md
CHANGED
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@@ -82,39 +82,39 @@ three tracks: **nucleic** (RNA/DNA and its per-position annotations), **protein*
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(amino-acid sequence, structure, and derived features), and **text** (free-text /
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categorical context). Each row here populates a subset of these under its short name
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(`raw` view) or its `tok_` key (`tokenized` view). The authoritative per-checkpoint
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-
list is `model.modality_info`. A few assay tracks (`atac`, `cage`, `rasp2`,
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`prot_abund`) are **context-conditional**: pass a free-text `context` alongside
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them to condition on cell-state / assay metadata — the `Conditioning context`
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column shows a real example for each.
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| Modality | Track | Description | Example | Conditioning context (`tok_context`) |
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|---|---|---|---|---|
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| `rna_seq` | nucleic | RNA/DNA nucleotide sequence (unspliced) — the core nucleic input | `"UUUGGAAACUUU…"` | — |
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| 93 |
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| `cds_junctions` | nucleic | Coding-sequence (CDS) exon–exon junction positions, per position | `"…0001000…"` | — |
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| 94 |
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| `splice_regions` | nucleic | Splice-region (exon) annotation, per position | `"…0011100…"` | — |
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| `splice_jctns_5cls` | nucleic | Per-position 5-class splice-site type: `0`=none, `1`=acceptor, `2`=donor, `3`=TSS (first-exon start), `4`=TES (last-exon end) | `"…00020…0100…"` | — |
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| `is_coding` | nucleic | Coding vs. non-coding flag | `[1]` | — |
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| `feature_type` | nucleic | Genomic feature-type label | `['protein_coding']` | — |
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| 98 |
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| `phylop_human` | nucleic | phyloP evolutionary-conservation score (human), per position | `[-0.66, 1.04, …]` | — |
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| `phylop_mouse` | nucleic | phyloP evolutionary-conservation score (mouse), per position | `[-0.26, -0.92, …]` | — |
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| 100 |
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| `atac` | nucleic | ATAC-seq chromatin-accessibility signal, per position (`N` = unmeasured). **Cell-state-conditional** | `"…NNNN…"` | `"human, GM23338 lymphoblastoid cell line (EBV-transformed B lymphocyte)"` |
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| `cage` | nucleic | CAGE transcription-start signal, per position. **Cell-state-conditional** | `[0.001, 0.001, …]` | `"skeletal muscle, human, fetal"` |
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| `rasp2` | nucleic | RASP2 (icSHAPE-style) RNA-structure reactivity, per position (`nan` where unmeasured). **Condition-conditional** | `[nan, 0.42, …]` | `"technology: icSHAPE, reagent: NAI-N3, in vivo, cell line: K562, human"` |
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| `aa_seq` | protein | Amino-acid (protein) sequence — the core protein input | `"MTPPERLFLP…"` | — |
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| `rna_codons` | protein | Codon sequence aligned to the protein (nucleotide content, protein-aligned track) | `['AUG', 'ACA', 'CCA', …]` | — |
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| `prot_struct` | protein | Protein 3D structure as ESM3 VQVAE tokens (decode to a backbone via `detokenize_structure`) | `
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| `dssp` | protein | DSSP secondary-structure class, per residue | `"CCXX…HHH…"` | — |
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| `sasa` | protein | Solvent-accessible surface area, per residue | `[225.1, 128.6, …]` | — |
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| `prot_abund` | protein | Protein abundance (PaxDb ppm), scalar. **Cell-state-conditional** | `[385.6]` | `"Leptospira interrogans (bacterium), control"` |
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| `funcprot_caption` | protein | Free-text protein functional caption | `"Catalyzes the hydrolysis of…"` | — |
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| `masif_charge` | protein | MaSIF surface Poisson–Boltzmann charge, per vertex | `[6.9, -3.3, …]` | — |
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| `masif_hbond` | protein | MaSIF surface hydrogen-bond potential, per vertex | `[-1.77, -1.64, …]` | — |
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| `masif_hydrophobicity` | protein | MaSIF surface hydrophobicity, per vertex | `[0.32, -0.31, …]` | — |
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| `masif_si_index` | protein | MaSIF surface shape-index, per vertex | `[0.34, 0.22, …]` | — |
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| `masif_n_vertices` | protein | MaSIF surface vertex count, per patch | `[65.0, 42.0, …]` | — |
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| `context` | text | Free-text semantic context (e.g. cell-state / assay) — the conditioning channel itself | `"HepG2 cell line"` | — |
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-
| `corpus` | text | Free-text biomedical literature (PubMed abstracts / articles), used as a language corpus | `"…regulates cell-cycle arrest and apoptosis…"` | — |
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| `gene_family_txt` | text | Organism taxonomic lineage as free text (broad clade → phylum → class → order → family → genus → species) | `"metazoa chordata mammalia primates hominidae homo homo sapiens"` | — |
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## See also
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(amino-acid sequence, structure, and derived features), and **text** (free-text /
|
| 83 |
categorical context). Each row here populates a subset of these under its short name
|
| 84 |
(`raw` view) or its `tok_` key (`tokenized` view). The authoritative per-checkpoint
|
| 85 |
+
list is `model.modality_info`. The `Dtype` column is the `raw`/decoded Python type; the `tokenized` config stores every modality as `list[int]`. A few assay tracks (`atac`, `cage`, `rasp2`,
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| 86 |
`prot_abund`) are **context-conditional**: pass a free-text `context` alongside
|
| 87 |
them to condition on cell-state / assay metadata — the `Conditioning context`
|
| 88 |
column shows a real example for each.
|
| 89 |
|
| 90 |
+
| Modality | Track | Dtype | Description | Example | Conditioning context (`tok_context`) |
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| 91 |
+
|---|---|---|---|---|---|
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| 92 |
+
| `rna_seq` | nucleic | `str` | RNA/DNA nucleotide sequence (unspliced) — the core nucleic input | `"UUUGGAAACUUU…"` | — |
|
| 93 |
+
| `cds_junctions` | nucleic | `str` | Coding-sequence (CDS) exon–exon junction positions, per position | `"…0001000…"` | — |
|
| 94 |
+
| `splice_regions` | nucleic | `str` | Splice-region (exon) annotation, per position | `"…0011100…"` | — |
|
| 95 |
+
| `splice_jctns_5cls` | nucleic | `str` | Per-position 5-class splice-site type: `0`=none, `1`=acceptor, `2`=donor, `3`=TSS (first-exon start), `4`=TES (last-exon end) | `"…00020…0100…"` | — |
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| 96 |
+
| `is_coding` | nucleic | `list[int]` | Coding vs. non-coding flag | `[1]` | — |
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| 97 |
+
| `feature_type` | nucleic | `list[str]` | Genomic feature-type label | `['protein_coding']` | — |
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| 98 |
+
| `phylop_human` | nucleic | `list[float]` | phyloP evolutionary-conservation score (human), per position | `[-0.66, 1.04, …]` | — |
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| 99 |
+
| `phylop_mouse` | nucleic | `list[float]` | phyloP evolutionary-conservation score (mouse), per position | `[-0.26, -0.92, …]` | — |
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| 100 |
+
| `atac` | nucleic | `str` | ATAC-seq chromatin-accessibility signal, per position (`N` = unmeasured). **Cell-state-conditional** | `"…NNNN…"` | `"human, GM23338 lymphoblastoid cell line (EBV-transformed B lymphocyte)"` |
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| 101 |
+
| `cage` | nucleic | `list[float]` | CAGE transcription-start signal, per position. **Cell-state-conditional** | `[0.001, 0.001, …]` | `"skeletal muscle, human, fetal"` |
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| 102 |
+
| `rasp2` | nucleic | `list[float]` | RASP2 (icSHAPE-style) RNA-structure reactivity, per position (`nan` where unmeasured). **Condition-conditional** | `[nan, 0.42, …]` | `"technology: icSHAPE, reagent: NAI-N3, in vivo, cell line: K562, human"` |
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| 103 |
+
| `aa_seq` | protein | `str` | Amino-acid (protein) sequence — the core protein input | `"MTPPERLFLP…"` | — |
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| 104 |
+
| `rna_codons` | protein | `list[str]` | Codon sequence aligned to the protein (nucleotide content, protein-aligned track) | `['AUG', 'ACA', 'CCA', …]` | — |
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| 105 |
+
| `prot_struct` | protein | `biotite AtomArray` | Protein 3D structure as ESM3 VQVAE tokens (decode to a backbone via `detokenize_structure`) | `AtomArray (backbone)` | — |
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| 106 |
+
| `dssp` | protein | `str` | DSSP secondary-structure class, per residue | `"CCXX…HHH…"` | — |
|
| 107 |
+
| `sasa` | protein | `list[float]` | Solvent-accessible surface area, per residue | `[225.1, 128.6, …]` | — |
|
| 108 |
+
| `prot_abund` | protein | `list[float]` | Protein abundance (PaxDb ppm), scalar. **Cell-state-conditional** | `[385.6]` | `"Leptospira interrogans (bacterium), control"` |
|
| 109 |
+
| `funcprot_caption` | protein | `str` | Free-text protein functional caption | `"Catalyzes the hydrolysis of…"` | — |
|
| 110 |
+
| `masif_charge` | protein | `list[float]` | MaSIF surface Poisson–Boltzmann charge, per vertex | `[6.9, -3.3, …]` | — |
|
| 111 |
+
| `masif_hbond` | protein | `list[float]` | MaSIF surface hydrogen-bond potential, per vertex | `[-1.77, -1.64, …]` | — |
|
| 112 |
+
| `masif_hydrophobicity` | protein | `list[float]` | MaSIF surface hydrophobicity, per vertex | `[0.32, -0.31, …]` | — |
|
| 113 |
+
| `masif_si_index` | protein | `list[float]` | MaSIF surface shape-index, per vertex | `[0.34, 0.22, …]` | — |
|
| 114 |
+
| `masif_n_vertices` | protein | `list[float]` | MaSIF surface vertex count, per patch | `[65.0, 42.0, …]` | — |
|
| 115 |
+
| `context` | text | `str` | Free-text semantic context (e.g. cell-state / assay) — the conditioning channel itself | `"HepG2 cell line"` | — |
|
| 116 |
+
| `corpus` | text | `str` | Free-text biomedical literature (PubMed abstracts / articles), used as a language corpus | `"…regulates cell-cycle arrest and apoptosis…"` | — |
|
| 117 |
+
| `gene_family_txt` | text | `str` | Organism taxonomic lineage as free text (broad clade → phylum → class → order → family → genus → species) | `"metazoa chordata mammalia primates hominidae homo homo sapiens"` | — |
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| 118 |
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| 119 |
## See also
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| 120 |
|