aliases
list
alignment_disposition
string
benchmark_case_id
string
benchmark_track
string
claim_uid
string
contract
dict
contract_sha256
string
migration_status
string
modality
string
pre_v2_contract_sha256
string
provenance
list
question
string
question_sha256
string
reference_id
string
scientific_core_sha256
string
semantic_cluster_id
string
target_family
string
task_ids
list
[ "adhd_fc_adhd200_site_split" ]
aligned
ncb-scientific-b0c4c5f349a00064
scientific
ncb-claim-8aa8d317c6056cb0
{ "claim_id": "adhd_fc_adhd200_site_split", "covariates": [ "age", "sex", "site" ], "discovery_cohort": "ADHD200_DISC", "estimand": { "direction": "two_sided", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "fc_fc_", "predic...
b0c4c5f349a00064aea1e57a9ed87aecb684446116668a035a31fe7e2c25d086
ready
fMRI-FC
b0c4c5f349a00064aea1e57a9ed87aecb684446116668a035a31fe7e2c25d086
[ { "prior_label": "fragile", "source_citation": "ADHD-200 Consortium 2012", "source_collection": "legacy_scientific", "source_id": "adhd_fc_adhd200_site_split", "source_mode": "literature", "source_path": "data/claims/fixed_literature_claims.csv", "target_family": "adhd" } ]
For ADHD case-control FC site-split in fMRI-FC, using ADHD200 site A as discovery and ADHD200 site B as replication, test the claim with expected direction two_sided and adjust for age;sex;site required when available.
9327ba43db3c8bfc32447c21feb8dc1e9768bab3c87baf1277fd377f3c97333f
ncb-scientific-b0c4c5f349a00064
5ac814cd691bf1e1d14eefa1e9906a7d06312319770893c6522f733b0db25bd9
ncb-sem-8aa8d317c6056cb0
adhd
[ "ncb21-task-2f198bcbf0cf7b42" ]
[ "brain_aging_hippocampus_adni_oasis3_cn" ]
aligned_with_safety_augmentation
ncb-scientific-b22524a12bd4a0b9
scientific
ncb-claim-f3e4911f433998d2
{ "claim_id": "brain_aging_hippocampus_adni_oasis3_cn", "covariates": [ "sex", "eTIV", "site" ], "discovery_cohort": "ADNI_DISC", "estimand": { "direction": "negative", "group": null, "outcome": "smri_hippocampus", "predictor": "age", "region_set": null, "type": "associatio...
b22524a12bd4a0b93a1526df97ea32199d9f08beef37d943ae1d4f7942ff7f5b
ready
sMRI
b22524a12bd4a0b93a1526df97ea32199d9f08beef37d943ae1d4f7942ff7f5b
[ { "prior_label": "known_positive", "source_citation": "Fjell and Walhovd 2010 Reviews in the Neurosciences", "source_collection": "legacy_scientific", "source_id": "brain_aging_hippocampus_adni_oasis3_cn", "source_mode": "literature", "source_path": "data/claims/fixed_literature_claims.csv",...
For brain aging hippocampal atrophy in CN adults in sMRI, using ADNI_CN as discovery and OASIS3_CN as replication, test the claim with expected direction negative and adjust for sex;eTIV when available.
5942338980a08aaa9cf5e973661fe3df2a80114b60ce0dee3ca67136ccb9b2ba
ncb-scientific-b22524a12bd4a0b9
48fe341ebfe1749a66fa45d30b851fb60d4cfa44272f1de27e7ba3c8f0c6d8cc
ncb-sem-f3e4911f433998d2
ad_aging
[ "ncb21-task-6110eb85e2d7580c" ]
[ "ad_wholebrain_atrophy_adni_oasis3" ]
aligned_with_safety_augmentation
ncb-scientific-b274fb2db756fa8f
scientific
ncb-claim-1aa85065ed1b8153
{ "claim_id": "ad_wholebrain_atrophy_adni_oasis3", "covariates": [ "age", "sex", "eTIV", "site" ], "discovery_cohort": "ADNI_DISC", "estimand": { "direction": "negative", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "smri_...
b274fb2db756fa8fbe67b5bf4c76aa14a96203ae5a5dae6222358380236562c8
ready
sMRI
b274fb2db756fa8fbe67b5bf4c76aa14a96203ae5a5dae6222358380236562c8
[ { "prior_label": "known_positive", "source_citation": "Jack et al. 2018 Alzheimer's & Dementia", "source_collection": "legacy_scientific", "source_id": "ad_wholebrain_atrophy_adni_oasis3", "source_mode": "literature", "source_path": "data/claims/fixed_literature_claims.csv", "target_fami...
For AD whole-brain atrophy in sMRI, using ADNI as discovery and OASIS3 as replication, test the claim with expected direction negative and adjust for age;sex;eTIV when available.
27b3b8973c48886671e13c09f7aba0b67e26d1c85bbef694fcd3d27c23592a03
ncb-scientific-b274fb2db756fa8f
ff8bfd8203bb2bd391fa1648d6dbf623a40c3bf3da0729e591de7a2d8fbe2678
ncb-sem-1aa85065ed1b8153
ad_aging
[ "ncb21-task-875cfcac9041998a" ]
[ "asd_q003" ]
aligned_with_safety_augmentation
ncb-scientific-b2bc1b3dc8d74234
scientific
ncb-claim-2166e66544e56e96
{ "claim_id": "asd_q003", "covariates": [ "age", "sex", "site" ], "discovery_cohort": "ABIDE1_DISC", "estimand": { "direction": "negative", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "fc_within_network", "predictor": "co...
b2bc1b3dc8d742349867f9f8a7e42fb3186657691ec0e71f041febf9a92913f6
ready
fMRI-FC
b2bc1b3dc8d742349867f9f8a7e42fb3186657691ec0e71f041febf9a92913f6
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "asd_q003", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "asd" } ]
In ABIDE1_DISC, with replication assessed in ABIDE1_REP, is fc_within_network lower in ASD than HC participants using dx as the predictor and no additional covariates?
dca138f48aa414436004e49ce89d984b557b2c9ddba97052b8a4ec9f2e1f8b8f
ncb-scientific-b2bc1b3dc8d74234
52d55c3f9660db4205ad27aba335895f8377bbd49b6fd0702300d037ab85e620
ncb-sem-2166e66544e56e96
asd
[ "ncb21-task-9844744e93e5574c" ]
[ "pubmed_29653095_29653095-psychosis-fc-02" ]
ambiguous_unresolved
ncb-scientific-b336c91ebd2e082c
scientific
ncb-claim-71354e62dc1c127c
{ "claim_id": "pubmed_29653095_29653095-psychosis-fc-02", "covariates": [ "age", "sex", "site" ], "discovery_cohort": "BSNIP2_DISC", "estimand": { "direction": "negative", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "fc_", ...
b336c91ebd2e082c670facfa74d1a9ee136e61e29d1305f2d91cecac8b77f04c
ambiguous_unresolved
fMRI-FC
b336c91ebd2e082c670facfa74d1a9ee136e61e29d1305f2d91cecac8b77f04c
[ { "prior_label": "candidate_unknown", "source_citation": "PMID:29653095; DOI:10.1016/j.bpsc.2016.07.001", "source_collection": "stage2_current", "source_id": "pubmed_29653095_29653095-psychosis-fc-02", "source_mode": "literature_grounded", "source_path": "review-stage/confirm-gates-all-gpt55...
For literature-grounded Relatives of psychosis probands versus healthy controls effect on large-scale resting-state network connectivity in fMRI-FC, using BSNIP2 as discovery and COBRE as replication, test the claim with expected direction negative and adjust for age;sex;site when available.
a0b8ab25b35aae132950a5e2d0a3008dec101dc4a40471771db13c4c6ec07fde
ncb-scientific-b336c91ebd2e082c
43b855c64b7c2cc5f63a22df184254771d788f101b301cfd61e9e920bdaa187a
ncb-sem-71354e62dc1c127c
psychosis
[]
[ "pubmed_26306871_pmid26306871_widespread_dementiaad_smri" ]
aligned
ncb-scientific-b5c857772b8292df
scientific
ncb-claim-4ea2939f05829de6
{ "claim_id": "pubmed_26306871_pmid26306871_widespread_dementiaad_smri", "covariates": [ "age", "sex", "eTIV" ], "discovery_cohort": "ADNI_DISC", "estimand": { "direction": "negative", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcom...
b5c857772b8292dff93bcb95c7fb4c0be82f61504c26048b086fe5058608e8d9
ready
sMRI
b5c857772b8292dff93bcb95c7fb4c0be82f61504c26048b086fe5058608e8d9
[ { "prior_label": "candidate_unknown", "source_citation": "PMID:26306871; DOI:10.1016/j.neuroscience.2015.08.033", "source_collection": "stage2_current", "source_id": "pubmed_26306871_pmid26306871_widespread_dementiaad_smri", "source_mode": "literature_grounded", "source_path": "review-stage/...
For literature-grounded dementia-stage Alzheimer's disease versus earlier-stage AD or non-AD comparison effect on hippocampal subfield morphology / widespread hippocampal atrophy in sMRI, using ADNI as discovery and OASIS3 as replication, test the claim with expected direction negative and adjust for age;eTIV;sex when ...
90428df4575c3939485af537eb6e2acb18986adeb5e47bd44912091fa7fd1bf5
ncb-scientific-b5c857772b8292df
3721ff6d1e234b4afdbc165fb6b70abb10b570b3715617de4b60a05e9fd1da25
ncb-sem-4ea2939f05829de6
ad_aging
[ "ncb21-task-9b0ef08d451df5cf" ]
[ "adhd_q033" ]
aligned
ncb-scientific-b6bcaf52ce24d411
scientific
ncb-claim-c9eae7560a1dd465
{ "claim_id": "adhd_q033", "covariates": [], "discovery_cohort": "ABCD_DISC", "estimand": { "direction": "two_sided", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "fc_fc_DorsAttn_Vis_z", "predictor": "confirm_dx", "region_set": null...
b6bcaf52ce24d41101405c05556ff4df7a5cf370d247fb9fbe590d817921a011
ready
fMRI-FC
b6bcaf52ce24d41101405c05556ff4df7a5cf370d247fb9fbe590d817921a011
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "adhd_q033", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "adhd" } ]
In ABCD_DISC and ABCD_REP separately, excluding missing dx, is ADHD status (dx=1.0 vs dx=0.0) associated with altered DorsalAttention-Visual connectivity (fc_fc_DorsAttn_Vis_z), with no additional covariates?
4534f60aebd59bf411dff332e7d4aa2e530c34c5d20aafc1bd860b07358677cb
ncb-scientific-b6bcaf52ce24d411
93603ccca3b3f6804922643703b6d1b7114815aa09b22a6552ac7771422f096e
ncb-sem-c9eae7560a1dd465
adhd
[ "ncb21-task-4958fc673b892c35" ]
[ "ad_aging_q017" ]
ambiguous_unresolved
ncb-scientific-b9f9592e3da6c9ce
scientific
ncb-claim-33fa545d5c370d9d
{ "claim_id": "ad_aging_q017", "covariates": [ "age", "sex", "eTIV", "site" ], "discovery_cohort": "ADNI_DISC", "estimand": { "direction": "positive", "group": null, "outcome": "pet_av45", "predictor": "beh_cdrsb", "region_set": null, "type": "association", "unit": ...
b9f9592e3da6c9ce77d0e6e3333175a7516b0e2a5a750a9dac682d3f3f346101
ambiguous_unresolved
PET
b9f9592e3da6c9ce77d0e6e3333175a7516b0e2a5a750a9dac682d3f3f346101
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "ad_aging_q017", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "ad_aging" ...
In ADNI_DISC, with ADNI_REP as a replication cohort, is increasing clinical impairment from CN to MCI to Dementia associated with progressively higher pet_av45, adjusting for age and sex?
9e31866f2bfdbe9a9189074872350ca77b8569ba9774d762b0d2b25f9dab3c33
ncb-scientific-b9f9592e3da6c9ce
2bac9ed1877c8bf83ff4f028e6096d6245a584b2f4fccaa1f5f5b5ae7d9ad0b3
ncb-sem-33fa545d5c370d9d
ad_aging
[]
[ "sz_fc_mean_abs_cobre_fbirn" ]
aligned_with_safety_augmentation
ncb-scientific-ba299f6826289883
scientific
ncb-claim-bcd31e36404b748e
{ "claim_id": "sz_fc_mean_abs_cobre_fbirn", "covariates": [ "age", "sex", "site" ], "discovery_cohort": "COBRE_DISC", "estimand": { "direction": "negative", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "fc_mean_abs", "pred...
ba299f6826289883e4daa74fa09ab631467ffc5d4032e7a7f330ebbddd782bc0
ready
fMRI-FC
ba299f6826289883e4daa74fa09ab631467ffc5d4032e7a7f330ebbddd782bc0
[ { "prior_label": "known_positive", "source_citation": "Pettersson-Yeo et al. 2011 Neuroscience and Biobehavioral Reviews", "source_collection": "legacy_scientific", "source_id": "sz_fc_mean_abs_cobre_fbirn", "source_mode": "literature", "source_path": "data/claims/fixed_literature_claims.csv...
For SZ reduced mean absolute FC in fMRI-FC, using COBRE as discovery and FBIRN as replication, test the claim with expected direction negative SZ minus HC on fc_mean_abs and adjust for age;sex when available.
6dc660eb115b8567babb0efbb128481762eda0174302a2dc5c791c7e412315c5
ncb-scientific-ba299f6826289883
06f6c06f61d12ba41f9edaffd5ddd520005aaab0eac6469eff6067812b325333
ncb-sem-bcd31e36404b748e
psychosis
[ "ncb21-task-e74a3902d3daab80" ]
[ "pubmed_36403658_pmid36403658_adhd_dmn_fc" ]
ambiguous_unresolved
ncb-scientific-bace4c130b60ece5
scientific
ncb-claim-cec2648b1254f921
{ "claim_id": "pubmed_36403658_pmid36403658_adhd_dmn_fc", "covariates": [ "age", "sex", "site" ], "discovery_cohort": "ABCD_DISC", "estimand": { "direction": "two_sided", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": [ "f...
bace4c130b60ece50157fd3d6ec0b0e4244cf860559cbcb48aa4a9e499ab497d
ambiguous_unresolved
fMRI-FC
bace4c130b60ece50157fd3d6ec0b0e4244cf860559cbcb48aa4a9e499ab497d
[ { "prior_label": "candidate_unknown", "source_citation": "PMID:36403658; DOI:10.1016/j.neuropsychologia.2022.108418", "source_collection": "stage2_current", "source_id": "pubmed_36403658_pmid36403658_adhd_dmn_fc", "source_mode": "literature_grounded", "source_path": "review-stage/confirm-gat...
For literature-grounded social phobia adolescents with ADHD comorbidity versus social phobia adolescents without ADHD comorbidity effect on default mode network functional connectivity in resting-state fMRI functional connectivity, using ABCD as discovery and ADHD200 as replication, test the claim with expected directi...
4e4a0ac838fc49628b0d6d5048b129e48f6035d11d7f896f927145106a42119a
ncb-scientific-bace4c130b60ece5
8f9662147729b791c8256fc5325ffcd4b256102185984ed4cc0c8242321c80f8
ncb-sem-cec2648b1254f921
adhd
[]
[ "normative_fmri_018" ]
aligned_with_safety_augmentation
ncb-scientific-bc6d05b49560e9df
scientific
ncb-claim-ea2068ac2f31ae27
{ "claim_id": "normative_fmri_018", "covariates": [ "age", "phen_fluid_composite", "site" ], "discovery_cohort": "HCP_DISC", "estimand": { "direction": "two_sided", "group": { "case": "F", "control": "M", "var": "sex" }, "outcome": "fc_fc_SalVentAttn_SalVentAttn_z...
bc6d05b49560e9df556c27a32ce7b1ba5f9f2ef45e09a11867a8804906ed9dcf
ready
fMRI-FC
bc6d05b49560e9df556c27a32ce7b1ba5f9f2ef45e09a11867a8804906ed9dcf
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "normative_fmri_018", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "norma...
In HCP_DISC, with replication in HCP_REP, do females and males differ in salience/ventral-attention within-network connectivity (fc_fc_SalVentAttn_SalVentAttn_z), adjusting for age and cognition?
dee65f72a47aff4d0e1ccbb29ba0c69bb7893bc2d8fbf51e2549b1c4bcdcbaa5
ncb-scientific-bc6d05b49560e9df
b004c255aa05390f098fb8b1cf40293d5b8f8a7644484f581710a21cd45094bf
ncb-sem-ea2068ac2f31ae27
normative_fmri
[ "ncb21-task-2a7a3de6b7d503b4" ]
[ "ad_aging_q021" ]
aligned_with_safety_augmentation
ncb-scientific-bd78b101a1f87be6
scientific
ncb-claim-d295d09b83e74459
{ "claim_id": "ad_aging_q021", "covariates": [ "age", "sex", "eTIV", "site" ], "discovery_cohort": "OASIS3_DISC", "estimand": { "direction": "negative", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "smri_hippocampus", ...
bd78b101a1f87be6fe2c3e88d31dc8e50bef5aafe3295b714c8df459f8c341e0
ready
sMRI
bd78b101a1f87be6fe2c3e88d31dc8e50bef5aafe3295b714c8df459f8c341e0
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "ad_aging_q021", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "ad_aging" ...
In OASIS3_DISC, with OASIS3_REP as a replication cohort, is Dementia associated with lower smri_hippocampus than CN, adjusting for age and sex?
ede7da991590f91e4bbee4c1cb0c6aec50937e0298fdeefea66c0e15a76c71b7
ncb-scientific-bd78b101a1f87be6
967b36b83187dc88df269ee0933d9e7ff8768454244e7a8113d4fa3d2f411668
ncb-sem-d295d09b83e74459
ad_aging
[ "ncb21-task-76fc7b6b4604ef89" ]
[ "pubmed_21729419_pmid21729419_1" ]
aligned
ncb-scientific-bdabe2252485052d
scientific
ncb-claim-35760c43a2264071
{ "claim_id": "pubmed_21729419_pmid21729419_1", "covariates": [ "age", "eTIV", "sex" ], "discovery_cohort": "ADNI_DISC", "estimand": { "direction": "positive", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "smri_", "predict...
bdabe2252485052d7dc57af8fa2e2b0c2ff1a6f8ceb218cf47d53bc6ff965cdd
ready
sMRI
bdabe2252485052d7dc57af8fa2e2b0c2ff1a6f8ceb218cf47d53bc6ff965cdd
[ { "prior_label": "candidate_unknown", "source_citation": "PMID:21729419; DOI:10.1017/S1041610211000913", "source_collection": "stage2_current", "source_id": "pubmed_21729419_pmid21729419_1", "source_mode": "literature_grounded", "source_path": "review-stage/confirm-gates-all-gpt55/combined_b...
For literature-grounded clinical dementia diagnosis or dementia-related disease group effect on regional/global cortical atrophy in sMRI, using ADNI as discovery and OASIS3 as replication, test the claim with expected direction positive and adjust for age;eTIV;sex when available.
afdd0d516b0e02ac11ff3e32a5a41532121f371c8b0d407f13ce0e2c6f41a3af
ncb-scientific-bdabe2252485052d
29980e4edc1ac46d117411d465e4ad43940dcb1be6bc2c4567f937bab48780ea
ncb-sem-35760c43a2264071
ad_aging
[ "ncb21-task-57c0fb95d68b794c" ]
[ "adhd_q009" ]
aligned_with_safety_augmentation
ncb-scientific-bdc24737aa23b682
scientific
ncb-claim-a93e2fa433789220
{ "claim_id": "adhd_q009", "covariates": [ "age", "sex", "site" ], "discovery_cohort": "ABCD_DISC", "estimand": { "direction": "two_sided", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "fc_fc_Limbic_SalVentAttn_z", "predic...
bdc24737aa23b68213ee1a77d82e33597f5039ce548624b69e5675e7b1b02b18
ready
fMRI-FC
bdc24737aa23b68213ee1a77d82e33597f5039ce548624b69e5675e7b1b02b18
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "adhd_q009", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "adhd" } ]
In ABCD_DISC, excluding missing dx, is ADHD status (dx=1.0 vs dx=0.0) associated with altered Limbic-Salience/VentralAttention connectivity (fc_fc_Limbic_SalVentAttn_z), with no additional covariates, and does the association replicate in ABCD_REP?
19f7933999dbf034aab1cba658fd2ba657b5373ecc87b7b0805823638f64981a
ncb-scientific-bdc24737aa23b682
b4d5415534cce368be98149cf72e0a4b63cabf56605c95d53afa73d2cf9a1d1f
ncb-sem-a93e2fa433789220
adhd
[ "ncb21-task-2de1487414a9935d" ]
[ "adhd_q016" ]
aligned
ncb-scientific-bdd01753f9ebb90c
scientific
ncb-claim-01555b96f5ff8e0a
{ "claim_id": "adhd_q016", "covariates": [], "discovery_cohort": "ADHD200_DISC", "estimand": { "direction": "negative", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "fc_fc_Cont_DorsAttn_z", "predictor": "confirm_dx", "region_set": n...
bdd01753f9ebb90c217a505dcc5198d851aee4b3c3450e682d1615f35e5dd44c
ready
fMRI-FC
bdd01753f9ebb90c217a505dcc5198d851aee4b3c3450e682d1615f35e5dd44c
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "adhd_q016", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "adhd" } ]
In ADHD200_DISC, is any ADHD diagnosis (dx in {1,2,3}) versus control (dx=0) associated with lower Control-DorsalAttention connectivity (fc_fc_Cont_DorsAttn_z), with no additional covariates, and is this direction replicated in ADHD200_REP?
c0c3136ae13104aee5f285b829af93f0169b1b014dbf9d271372f37ae8fa88ae
ncb-scientific-bdd01753f9ebb90c
3c4e0dd4c3da2ffbbe9f17a1ccfe1369e3536e836b048d0b1367da3b5ba30254
ncb-sem-01555b96f5ff8e0a
adhd
[ "ncb21-task-d6d1c76b3d01b0bd" ]
[ "ad_aging_q007" ]
ambiguous_unresolved
ncb-scientific-be6c2a9394bf0498
scientific
ncb-claim-c7d492887bd930e8
{ "claim_id": "ad_aging_q007", "covariates": [ "age", "sex", "eTIV", "site" ], "discovery_cohort": "ADNI_DISC", "estimand": { "direction": "negative", "group": null, "outcome": "smri_hippocampus", "predictor": "beh_cdrsb", "region_set": null, "type": "association", ...
be6c2a9394bf0498514b7f9b8a7c090d0eecae63bc6a4851a3b2daab83152219
ambiguous_unresolved
sMRI
be6c2a9394bf0498514b7f9b8a7c090d0eecae63bc6a4851a3b2daab83152219
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "ad_aging_q007", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "ad_aging" ...
In ADNI_DISC, with ADNI_REP as a replication cohort, is increasing clinical impairment from CN to MCI to Dementia associated with progressively lower smri_hippocampus, adjusting for age and sex?
10c81700d8723ab87ddfb3fe5342761a768d8bf9c254994d5b9db9c5f2661c95
ncb-scientific-be6c2a9394bf0498
2edb5d8fa5b83c1c9db42020a371ebda6135c3cfc6a2842f86f95593b4193e38
ncb-sem-c7d492887bd930e8
ad_aging
[]
[ "asd_q049" ]
aligned_with_safety_augmentation
ncb-scientific-be9238714808b664
scientific
ncb-claim-63f13b156feb0458
{ "claim_id": "asd_q049", "covariates": [ "age", "sex", "site" ], "discovery_cohort": "ABIDE2_DISC", "estimand": { "direction": "two_sided", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "fc_fc_Default_SalVentAttn_z", "pred...
be9238714808b66402159f2c45825993dd00eadd147b39f453e2e7e450668e79
ready
fMRI-FC
be9238714808b66402159f2c45825993dd00eadd147b39f453e2e7e450668e79
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "asd_q049", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "asd" } ]
In ABIDE2_DISC, with replication assessed in ABIDE2_REP, does fc_fc_Default_SalVentAttn_z differ between dx=1 and dx=2 participants using dx as the predictor and no additional covariates?
b3fa42d2a630ebc3caa7c74fb7cbd7662c049cc3c860cb5ce03902ac58d726a8
ncb-scientific-be9238714808b664
f4f5fce5721cac343ee2ceb3ff15aaf6f61f515a0a4ed97faeb874be0e847473
ncb-sem-63f13b156feb0458
asd
[ "ncb21-task-ceeb9f8bb890690b" ]
[ "ad_aging_q029" ]
aligned_with_safety_augmentation
ncb-scientific-bf6a4a4dabf8357f
scientific
ncb-claim-35771173cccac1ce
{ "claim_id": "ad_aging_q029", "covariates": [ "sex", "eTIV", "site" ], "discovery_cohort": "OASIS3_DISC", "estimand": { "direction": "negative", "group": null, "outcome": "smri_wholebrain", "predictor": "age", "region_set": null, "type": "association", "unit": "scalar"...
bf6a4a4dabf8357f31e6a07ae1504771c332c4ed81929fb895a09609631d5866
ready
sMRI
bf6a4a4dabf8357f31e6a07ae1504771c332c4ed81929fb895a09609631d5866
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "ad_aging_q029", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "ad_aging" ...
In OASIS3_DISC, among CN participants, is older age associated with lower smri_wholebrain, adjusting for sex?
471346971a5ea41cfb190c9fabcbd47a7800e7ac5bf957af51dac02889ff6aba
ncb-scientific-bf6a4a4dabf8357f
5431056f103431ae8623f219ada1d4abec04b25cb89eaceb664b3c61380a9985
ncb-sem-35771173cccac1ce
ad_aging
[ "ncb21-task-fb80325a3bdd78f7" ]
[ "pubmed_34183210_pmid34183210_1" ]
ambiguous_unresolved
ncb-scientific-c1112f228bb27f06
scientific
ncb-claim-19a40eeeb50e9d61
{ "claim_id": "pubmed_34183210_pmid34183210_1", "covariates": [ "age", "sex", "site" ], "discovery_cohort": "BSNIP2_DISC", "estimand": { "direction": "negative", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "fc_", "predict...
c1112f228bb27f06f18f32376d89a4b816fcc7df2f53487617d65faedc726ef5
ambiguous_unresolved
fMRI-FC
c1112f228bb27f06f18f32376d89a4b816fcc7df2f53487617d65faedc726ef5
[ { "prior_label": "candidate_unknown", "source_citation": "PMID:34183210; DOI:10.1016/j.schres.2021.06.010", "source_collection": "stage2_current", "source_id": "pubmed_34183210_pmid34183210_1", "source_mode": "literature_grounded", "source_path": "review-stage/confirm-gates-all-gpt55/combine...
For literature-grounded breakthrough psychosis relapse on ongoing antipsychotic maintenance vs healthy controls effect on striatal resting-state functional connectivity / striatal connectivity index in fMRI-FC, using BSNIP2 as discovery and COBRE as replication, test the claim with expected direction negative and adjus...
3e8049b7ffb2a51555b02995586bc5ac758cba8fc9b0e435c93488e887e2ff70
ncb-scientific-c1112f228bb27f06
13f948aa9761a6df676c1a656b12123f767ca72101992773231b95bb65b418b7
ncb-sem-19a40eeeb50e9d61
psychosis
[]
[ "normative_fmri_033" ]
aligned_with_safety_augmentation
ncb-scientific-c1b8f2bee08cd388
scientific
ncb-claim-5963ec53b7af56d7
{ "claim_id": "normative_fmri_033", "covariates": [ "sex", "phen_fluid_composite", "site" ], "discovery_cohort": "ABCD_DISC", "estimand": { "direction": "negative", "group": null, "outcome": "fc_fc_Default_DorsAttn_z", "predictor": "age", "region_set": null, "type": "associ...
c1b8f2bee08cd3885ae393bad4189abe4f6f306525a43073ef666674c49e6e5a
ready
fMRI-FC
c1b8f2bee08cd3885ae393bad4189abe4f6f306525a43073ef666674c49e6e5a
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "normative_fmri_033", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "norma...
Among ABCD participants with dx=0.0, in ABCD_DISC with replication in ABCD_REP, is higher age associated with lower default-mode to dorsal-attention connectivity (fc_fc_Default_DorsAttn_z), adjusting for sex and cognition?
bbb2f5d0337d98ca21d01363117c8802166d00564d52138fc36095d6b7896a14
ncb-scientific-c1b8f2bee08cd388
8c0792a412bce1cdbee17765d082e161d376aeeb834a9e479c512f09a5e9ac72
ncb-sem-5963ec53b7af56d7
normative_fmri
[ "ncb21-task-0244deeb8ae44e7b" ]
[ "ad_aging_q018" ]
ambiguous_unresolved
ncb-scientific-c2b02d58d24ba60d
scientific
ncb-claim-46482d6107f7b115
{ "claim_id": "ad_aging_q018", "covariates": [ "age", "sex", "eTIV", "site" ], "discovery_cohort": "ADNI_DISC", "estimand": { "direction": "negative", "group": null, "outcome": "pet_fdg_suvr", "predictor": "beh_cdrsb", "region_set": null, "type": "association", "uni...
c2b02d58d24ba60daf2b0fab1860326813cfd95d682e7e00098e44931d13b8a2
ambiguous_unresolved
PET
c2b02d58d24ba60daf2b0fab1860326813cfd95d682e7e00098e44931d13b8a2
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "ad_aging_q018", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "ad_aging" ...
In ADNI_DISC, with ADNI_REP as a replication cohort, is increasing clinical impairment from CN to MCI to Dementia associated with progressively lower pet_fdg_suvr, adjusting for age and sex?
c6fc271e53fb2d68fd2b594f1ca2451ed500ac56580dfd87511ad028dd86246b
ncb-scientific-c2b02d58d24ba60d
6942871f45fb044cbe81a6633afa1dfb0a6a05fe3e73cbe2576817576e8ad9da
ncb-sem-46482d6107f7b115
ad_aging
[]
[ "pubmed_35388950_pmid35388950_ad_havas_detection" ]
aligned
ncb-scientific-c3a081875a1cf586
scientific
ncb-claim-6c7a1e7db4b6dcd5
{ "claim_id": "pubmed_35388950_pmid35388950_ad_havas_detection", "covariates": [ "age", "eTIV", "sex" ], "discovery_cohort": "ADNI_DISC", "estimand": { "direction": "positive", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "smr...
c3a081875a1cf586a007ce8ca93186b5680d0217ed8d6cb1ee78167cf39f91bb
ready
sMRI
c3a081875a1cf586a007ce8ca93186b5680d0217ed8d6cb1ee78167cf39f91bb
[ { "prior_label": "candidate_unknown", "source_citation": "PMID:35388950; DOI:10.1002/hbm.25850", "source_collection": "stage2_current", "source_id": "pubmed_35388950_pmid35388950_ad_havas_detection", "source_mode": "literature_grounded", "source_path": "review-stage/confirm-gates-all-gpt55/c...
For literature-grounded Higher HAVAs / Alzheimer disease versus control status effect on Alzheimer disease detection / diagnostic classification in sMRI volumetric MRI, using ADNI as discovery and OASIS3 as replication, test the claim with expected direction positive and adjust for age;eTIV;sex when available.
f53f8e95dae61c20b6955e509af8491a6986c33474734d95c5ddad01b32666c6
ncb-scientific-c3a081875a1cf586
536c28b3f83e9d521d3da2f902f7291bd66d3a5761f155fc269b3c36996e62fb
ncb-sem-6c7a1e7db4b6dcd5
ad_aging
[ "ncb21-task-61b1b74fe9df4b4f" ]
[ "asd_q038" ]
aligned_with_safety_augmentation
ncb-scientific-c631e745a39a4c34
scientific
ncb-claim-36d900948ef5a6c9
{ "claim_id": "asd_q038", "covariates": [ "age", "sex", "site" ], "discovery_cohort": "ABIDE2_DISC", "estimand": { "direction": "two_sided", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "fc_fc_Vis_Vis", "predictor": "confi...
c631e745a39a4c34b7a2b47ee20ac723363fb4d3f247ba63938ada9c0511f640
ready
fMRI-FC
c631e745a39a4c34b7a2b47ee20ac723363fb4d3f247ba63938ada9c0511f640
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "asd_q038", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "asd" } ]
In ABIDE2_DISC, with replication assessed in ABIDE2_REP, does fc_fc_Vis_Vis differ between dx=1 and dx=2 participants using dx as the predictor and no additional covariates?
fafd5037b8601c23c53be1427181a301e0c7cb55c0ce7ed82f6c3f9c922fedde
ncb-scientific-c631e745a39a4c34
d58de6cb3567b771970ef7e1781d5993de3bfdc0c51b47480687006ae9781bf5
ncb-sem-36d900948ef5a6c9
asd
[ "ncb21-task-2378bd6a4aa6d917" ]
[ "adhd_q031" ]
aligned_with_safety_augmentation
ncb-scientific-c64dac21d8591104
scientific
ncb-claim-4297ac55ed4096d3
{ "claim_id": "adhd_q031", "covariates": [ "age", "sex", "site" ], "discovery_cohort": "ABCD_DISC", "estimand": { "direction": "two_sided", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "fc_fc_Limbic_Vis_z", "predictor": "c...
c64dac21d8591104aa2912c0fc623cb3df7ae2fad45f89683dcc7f18692dc403
ready
fMRI-FC
c64dac21d8591104aa2912c0fc623cb3df7ae2fad45f89683dcc7f18692dc403
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "adhd_q031", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "adhd" } ]
In ABCD_DISC and ABCD_REP separately, excluding missing dx, do ADHD cases (dx=1.0) differ from controls (dx=0.0) in Limbic-Visual connectivity (fc_fc_Limbic_Vis_z), with no additional covariates?
4037e2e75b04cd9206d8c402d57a297ff5c80638d0578700e00a403422e06da0
ncb-scientific-c64dac21d8591104
c324ba257320a23e560e6c562bf89909368d9cd09f43cd48515fe66601be4753
ncb-sem-4297ac55ed4096d3
adhd
[ "ncb21-task-a32df69d3ffcf15e" ]
[ "pubmed_29653095_29653095-psychosis-fc-01" ]
aligned
ncb-scientific-c671d3de1b2734cb
scientific
ncb-claim-71354e62dc1c127c
{ "claim_id": "pubmed_29653095_29653095-psychosis-fc-01", "covariates": [ "age", "sex", "site" ], "discovery_cohort": "BSNIP2_DISC", "estimand": { "direction": "negative", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "fc_", ...
c671d3de1b2734cb8e64ccc55fdd15ea4118e551d604845c6f756f7b71f7ba43
ready
fMRI-FC
c671d3de1b2734cb8e64ccc55fdd15ea4118e551d604845c6f756f7b71f7ba43
[ { "prior_label": "candidate_unknown", "source_citation": "PMID:29653095; DOI:10.1016/j.bpsc.2016.07.001", "source_collection": "stage2_current", "source_id": "pubmed_29653095_29653095-psychosis-fc-01", "source_mode": "literature_grounded", "source_path": "review-stage/confirm-gates-all-gpt55...
For literature-grounded Psychosis probands versus healthy controls effect on large-scale resting-state network connectivity in fMRI-FC, using BSNIP2 as discovery and COBRE as replication, test the claim with expected direction negative and adjust for age;sex;site when available.
54acffd20c41e9a0c533f35de4add5b79743714fedc400c8ca10b2f70357ed1f
ncb-scientific-c671d3de1b2734cb
43b855c64b7c2cc5f63a22df184254771d788f101b301cfd61e9e920bdaa187a
ncb-sem-71354e62dc1c127c
psychosis
[ "ncb21-task-2af7eda20deedfc3" ]
[ "asd_q041" ]
aligned_with_safety_augmentation
ncb-scientific-c823298f5f12df8a
scientific
ncb-claim-7b2670c1d81fe2d1
{ "claim_id": "asd_q041", "covariates": [ "age", "sex", "site" ], "discovery_cohort": "ABIDE2_DISC", "estimand": { "direction": "two_sided", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "fc_fc_Cont_DorsAttn_z", "predictor"...
c823298f5f12df8af07efc39e57413ee6b375c5f9f95bf060e712101c70c15cd
ready
fMRI-FC
c823298f5f12df8af07efc39e57413ee6b375c5f9f95bf060e712101c70c15cd
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "asd_q041", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "asd" } ]
In ABIDE2_DISC, with replication assessed in ABIDE2_REP, does fc_fc_Cont_DorsAttn_z differ between dx=1 and dx=2 participants using dx as the predictor and no additional covariates?
82b424dd24392485dfe0585b2ac8274ad9969c38a52bb25afb4c2cb29a0b96dc
ncb-scientific-c823298f5f12df8a
ee197ababc2ae9042952f1fd8de0b47a4193ab15f3f80c00617bbda61704bbe2
ncb-sem-7b2670c1d81fe2d1
asd
[ "ncb21-task-f881acc3dcf78298" ]
[ "age_fc_ukb_hcpaging" ]
aligned
ncb-scientific-c82528795d17b7c6
scientific
ncb-claim-be8fecd97effd5a6
{ "claim_id": "age_fc_ukb_hcpaging", "covariates": [ "sex", "site" ], "discovery_cohort": "UKB_DISC", "estimand": { "direction": "two_sided", "group": null, "outcome": "fc_fc_", "predictor": "age", "region_set": "fMRI-FC_descriptors", "type": "association", "unit": "brainwi...
c82528795d17b7c659e88c258f82c4bdc65f014ab3c9395aebbff53f8ce8f938
ready
fMRI-FC
c82528795d17b7c659e88c258f82c4bdc65f014ab3c9395aebbff53f8ce8f938
[ { "prior_label": "candidate_unknown", "source_citation": "Fjell and Walhovd 2010 review [VERIFY]", "source_collection": "legacy_scientific", "source_id": "age_fc_ukb_hcpaging", "source_mode": "literature", "source_path": "data/claims/fixed_literature_claims.csv", "target_family": "normat...
For age association with FC descriptors in fMRI-FC, using UKB as discovery and HCP_Aging as replication, test the claim with expected direction two_sided and adjust for sex;site when available.
f6b397b4b28300ff4f43288ee09466e26e46a3a6b5a4c1b1c606378f878bfc21
ncb-scientific-c82528795d17b7c6
e9532af40954d25b3a29ccf7428e612faad30103af352d45ed7f18c563be564d
ncb-sem-be8fecd97effd5a6
normative_fmri
[ "ncb21-task-3ae580adaf8733fe" ]
[ "ad_aging_q022" ]
aligned_with_safety_augmentation
ncb-scientific-c865d685dc0a2c5f
scientific
ncb-claim-ed01d7c380e3f82b
{ "claim_id": "ad_aging_q022", "covariates": [ "age", "sex", "eTIV", "site" ], "discovery_cohort": "OASIS3_DISC", "estimand": { "direction": "negative", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "smri_entorhinal", "...
c865d685dc0a2c5f04eeb7dc04fd4ed41e08db9bc66836e61819a499843a0b59
ready
sMRI
c865d685dc0a2c5f04eeb7dc04fd4ed41e08db9bc66836e61819a499843a0b59
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "ad_aging_q022", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "ad_aging" ...
In OASIS3_DISC, with OASIS3_REP as a replication cohort, is Dementia associated with lower smri_entorhinal than CN, adjusting for age and sex?
f5d8c73a9e5538cc47bcab0348b439234a57f53b31b88b1a360749270bd2dc25
ncb-scientific-c865d685dc0a2c5f
91684ea73962378d4810a497d31e9c5d4ff40e7c677bee88082ac6ff19469054
ncb-sem-ed01d7c380e3f82b
ad_aging
[ "ncb21-task-ed121570c699b6ea" ]
[ "pubmed_31265198_pmid31265198_fc_adhd_vs_tdc" ]
aligned
ncb-scientific-c8acae9508ef35fd
scientific
ncb-claim-1671056a239d54c1
{ "claim_id": "pubmed_31265198_pmid31265198_fc_adhd_vs_tdc", "covariates": [ "age", "sex", "site" ], "discovery_cohort": "ABCD_DISC", "estimand": { "direction": "negative", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "fc_fc_"...
c8acae9508ef35fd71e17be422a96ff94cda16d53561647f67cc34bf3fb5e2dc
ready
fMRI-FC
c8acae9508ef35fd71e17be422a96ff94cda16d53561647f67cc34bf3fb5e2dc
[ { "prior_label": "candidate_unknown", "source_citation": "PMID:31265198; DOI:10.1002/jmri.26854", "source_collection": "stage2_current", "source_id": "pubmed_31265198_pmid31265198_fc_adhd_vs_tdc", "source_mode": "literature_grounded", "source_path": "review-stage/confirm-gates-all-gpt55/comb...
For literature-grounded ADHD patients versus typically developing controls effect on seed-based functional connectivity in resting-state fMRI functional connectivity, using ABCD as discovery and ADHD200 as replication, test the claim with expected direction negative and adjust for age;sex;site when available.
496881fa0a06016a7fe25e29742550dbf996ec2b05312029a2998e312a09c937
ncb-scientific-c8acae9508ef35fd
7168dd728c1670843341d19e4c97ff0a5c3eca44d33cc9bd4528b2bfdf4a1bf1
ncb-sem-1671056a239d54c1
adhd
[ "ncb21-task-f9773dc8fdf57d18" ]
[ "adhd_q003" ]
aligned
ncb-scientific-c8faa8d62af041ef
scientific
ncb-claim-d1d63849392e8fad
{ "claim_id": "adhd_q003", "covariates": [], "discovery_cohort": "ABCD_DISC", "estimand": { "direction": "negative", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "fc_fc_Cont_Default_z", "predictor": "confirm_dx", "region_set": null,...
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ready
fMRI-FC
c8faa8d62af041ef89350be38a83cbeb57d551b518e3e17905b78d1b51c85218
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "adhd_q003", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "adhd" } ]
In ABCD_DISC, excluding missing dx, do participants with ADHD (dx=1.0) show lower Control-Default connectivity (fc_fc_Cont_Default_z) than controls (dx=0.0), with no additional covariates, and is the direction consistent in ABCD_REP?
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ncb-scientific-c8faa8d62af041ef
758cdfac9f43918992acb1dc91d5d532a050d52df8d1826a62f73f94f96c13e8
ncb-sem-d1d63849392e8fad
adhd
[ "ncb21-task-6a44a66368a81a10" ]
[ "ad_aging_q032" ]
aligned_with_safety_augmentation
ncb-scientific-c922885057dbc163
scientific
ncb-claim-1bd1a60a1440fb79
{ "claim_id": "ad_aging_q032", "covariates": [ "sex", "eTIV", "site" ], "discovery_cohort": "ADNI_DISC", "estimand": { "direction": "positive", "group": null, "outcome": "smri_ventricles", "predictor": "age", "region_set": null, "type": "association", "unit": "scalar" ...
c922885057dbc163bc0da7c09a1f929618f4043b01e964bfbd4ba2d3947e992e
ready
sMRI
c922885057dbc163bc0da7c09a1f929618f4043b01e964bfbd4ba2d3947e992e
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "ad_aging_q032", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "ad_aging" ...
In ADNI_DISC, among CN participants, is older age associated with higher smri_ventricles, adjusting for sex?
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ncb-scientific-c922885057dbc163
f3dc0ac494a0ed981fbab4e790bc4b2193f7bc8a0ca61cd46ce52328aa075fcd
ncb-sem-1bd1a60a1440fb79
ad_aging
[ "ncb21-task-49c64dd2a4b213fa" ]
[ "normative_fmri_031" ]
aligned_with_safety_augmentation
ncb-scientific-c9246d08669f6265
scientific
ncb-claim-027c48c5b3ac8f14
{ "claim_id": "normative_fmri_031", "covariates": [ "sex", "phen_fluid_composite", "site" ], "discovery_cohort": "ABCD_DISC", "estimand": { "direction": "positive", "group": null, "outcome": "fc_fc_Cont_Cont_z", "predictor": "age", "region_set": null, "type": "association",...
c9246d08669f6265e26d6a274208eaff54a2c585d734065f5cd7d4289f86a6ed
ready
fMRI-FC
c9246d08669f6265e26d6a274208eaff54a2c585d734065f5cd7d4289f86a6ed
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "normative_fmri_031", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "norma...
Among ABCD participants with dx=0.0, in ABCD_DISC with replication in ABCD_REP, is higher age associated with higher control-network within-network connectivity (fc_fc_Cont_Cont_z), adjusting for sex and cognition?
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ncb-scientific-c9246d08669f6265
556803894ff3fc4e4c1913687e5b1e57f356f27549f7ac2b37c4250be981bdae
ncb-sem-027c48c5b3ac8f14
normative_fmri
[ "ncb21-task-1a9d9bff2f919e15" ]
[ "pubmed_37121277_pmid37121277_mccfc_cluster2_vs_td" ]
ambiguous_unresolved
ncb-scientific-c98428886dd0f1d9
scientific
ncb-claim-5764b4fe5f95de4a
{ "claim_id": "pubmed_37121277_pmid37121277_mccfc_cluster2_vs_td", "covariates": [ "age", "sex", "site" ], "discovery_cohort": "ABIDE2_DISC", "estimand": { "direction": "negative", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": ...
c98428886dd0f1d91c3a75d885826b5fb7726225297f515afa05718599e2996d
ambiguous_unresolved
fMRI-FC
c98428886dd0f1d91c3a75d885826b5fb7726225297f515afa05718599e2996d
[ { "prior_label": "candidate_unknown", "source_citation": "PMID:37121277; DOI:10.1016/j.bbr.2023.114458", "source_collection": "stage2_current", "source_id": "pubmed_37121277_pmid37121277_mccfc_cluster2_vs_td", "source_mode": "literature_grounded", "source_path": "review-stage/confirm-gates-a...
For literature-grounded ASD Cluster-2 with moderate ADI-R impairment versus typical-development controls effect on MCC-related whole-brain functional connectivity in resting-state fMRI functional connectivity, using ABIDE2 as discovery and ABIDE2 as replication, test the claim with expected direction negative and adjus...
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ncb-scientific-c98428886dd0f1d9
7479f5b2f60e18191ed5f30360e3fe7c2f540dce44899019cd404899ee0a94db
ncb-sem-5764b4fe5f95de4a
asd
[]
[ "asd_q033" ]
aligned_with_safety_augmentation
ncb-scientific-caeb5a6d248ba33c
scientific
ncb-claim-c302e042c0fc115a
{ "claim_id": "asd_q033", "covariates": [ "age", "sex", "site" ], "discovery_cohort": "ABIDE2_DISC", "estimand": { "direction": "two_sided", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "fc_fc_SalVentAttn_SalVentAttn", "pr...
caeb5a6d248ba33c770c82b3dc6515580c3efad63440adbbb4688d39731a3c41
ready
fMRI-FC
caeb5a6d248ba33c770c82b3dc6515580c3efad63440adbbb4688d39731a3c41
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "asd_q033", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "asd" } ]
In ABIDE2_DISC, with replication assessed in ABIDE2_REP, does fc_fc_SalVentAttn_SalVentAttn differ between dx=1 and dx=2 participants using dx as the predictor and no additional covariates?
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ncb-scientific-caeb5a6d248ba33c
cb7cd847e1f3d937368cbef16af739b74c4188b1c7861d075cb5c6de7fc1d117
ncb-sem-c302e042c0fc115a
asd
[ "ncb21-task-f78467ff31f5d941" ]
[ "normative_fmri_026" ]
aligned_with_safety_augmentation
ncb-scientific-cb339bf30281cede
scientific
ncb-claim-54412458ba1b1520
{ "claim_id": "normative_fmri_026", "covariates": [ "sex", "phen_fluid_composite", "site" ], "discovery_cohort": "HCP_Aging_DISC", "estimand": { "direction": "negative", "group": null, "outcome": "fc_fc_SomMot_SomMot_z", "predictor": "age", "region_set": null, "type": "asso...
cb339bf30281cedea3769b3c8ba3c0199ad8889c6569c72e5720af2c4c1b226d
ready
fMRI-FC
cb339bf30281cedea3769b3c8ba3c0199ad8889c6569c72e5720af2c4c1b226d
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "normative_fmri_026", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "norma...
In HCP_Aging_DISC, with replication in HCP_Aging_REP, is higher age associated with lower somatomotor within-network connectivity (fc_fc_SomMot_SomMot_z), adjusting for sex and cognition?
0aa2228a096b0e664538eeb85ad592e24e1e86c968e157af074ef47570ee4519
ncb-scientific-cb339bf30281cede
a301c2c36e13898584f2156b1a29e59116fbbeaa86958bf463ba6a44cf7d0288
ncb-sem-54412458ba1b1520
normative_fmri
[ "ncb21-task-3d920ec7800c2bfa" ]
[ "pubmed_28040544_pmid28040544_asd_fc_kea_corticalnetworks" ]
aligned
ncb-scientific-cb86d4103ebb0e0c
scientific
ncb-claim-2bf57780df2813c6
{ "claim_id": "pubmed_28040544_pmid28040544_asd_fc_kea_corticalnetworks", "covariates": [ "age", "sex", "site" ], "discovery_cohort": "ABIDE2_DISC", "estimand": { "direction": "negative", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "out...
cb86d4103ebb0e0cfb84aeae03b006b1b9f5e196a73b165f42e271c167d1f8d0
ready
fMRI-FC
cb86d4103ebb0e0cfb84aeae03b006b1b9f5e196a73b165f42e271c167d1f8d0
[ { "prior_label": "candidate_unknown", "source_citation": "PMID:28040544; DOI:10.1016/j.neuroimage.2016.12.068", "source_collection": "stage2_current", "source_id": "pubmed_28040544_pmid28040544_asd_fc_kea_corticalnetworks", "source_mode": "literature_grounded", "source_path": "review-stage/c...
For literature-grounded Autism diagnosis versus control status effect on Resting-state functional connectivity in KEA-defined cortical networks involving orbitofrontal cortex, anterior cingulate cortex, middle temporal gyrus, and precuneus in fMRI-FC, using ABIDE2 as discovery and ABIDE2 as replication, test the claim ...
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ncb-scientific-cb86d4103ebb0e0c
2eb4eeb12f6080c6e3aeb98bd813f454f2d1004f546c9b164dfeadf3a4ca35c6
ncb-sem-2bf57780df2813c6
asd
[ "ncb21-task-d3daf7fbc0850859" ]
[ "ad_aging_q036" ]
aligned_with_safety_augmentation
ncb-scientific-cc1c11b70cdbc35f
scientific
ncb-claim-4cf6bd4d0048276f
{ "claim_id": "ad_aging_q036", "covariates": [ "sex", "eTIV", "site" ], "discovery_cohort": "ADNI_DISC", "estimand": { "direction": "positive", "group": null, "outcome": "pet_av45", "predictor": "age", "region_set": null, "type": "association", "unit": "scalar" }, "...
cc1c11b70cdbc35f0fb7b7692822abca760f09315d96cba5c2e0c0d8c07fcfe3
ready
PET
cc1c11b70cdbc35f0fb7b7692822abca760f09315d96cba5c2e0c0d8c07fcfe3
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "ad_aging_q036", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "ad_aging" ...
In ADNI_DISC, among CN participants, is older age associated with higher pet_av45, adjusting for sex?
17ef9671c214ecfe60e3d1d6f4a056a94c24992d89c2b4b35ee417f8bfc4cfc2
ncb-scientific-cc1c11b70cdbc35f
33630bae3c1c57446d8568d4a1d6be8caffddf55aa18b716e424c71fe7c68e23
ncb-sem-4cf6bd4d0048276f
ad_aging
[ "ncb21-task-a389468db376c4f4" ]
[ "ad_aging_q025" ]
aligned_with_safety_augmentation
ncb-scientific-cc2914e36309cad4
scientific
ncb-claim-5ec25f86a95995a3
{ "claim_id": "ad_aging_q025", "covariates": [ "age", "sex", "eTIV", "site" ], "discovery_cohort": "OASIS3_DISC", "estimand": { "direction": "negative", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "smri_midtemp", "pre...
cc2914e36309cad42e9bff4b0a6351fa56b156cb121cb9074b25063a25f3fff5
ready
sMRI
cc2914e36309cad42e9bff4b0a6351fa56b156cb121cb9074b25063a25f3fff5
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "ad_aging_q025", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "ad_aging" ...
In OASIS3_DISC, with OASIS3_REP as a replication cohort, is Dementia associated with lower smri_midtemp than CN, adjusting for age and sex?
d325e8268a83c8fa1541ef6341c812f8d9c73d2eac79f89951e182a9591e7688
ncb-scientific-cc2914e36309cad4
3ad59694b84444ecb7f263e017fbe73bd62dd8beaaa1603c826756e4ba546c5b
ncb-sem-5ec25f86a95995a3
ad_aging
[ "ncb21-task-0a1ed327c94ac9a5" ]
[ "adhd_q007" ]
aligned_with_safety_augmentation
ncb-scientific-ccf76ee04722df94
scientific
ncb-claim-a78bc3d5c2482eab
{ "claim_id": "adhd_q007", "covariates": [ "age", "sex", "site" ], "discovery_cohort": "ABCD_DISC", "estimand": { "direction": "two_sided", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "fc_fc_DorsAttn_DorsAttn_z", "predict...
ccf76ee04722df945c7c574a27b2da49fc63bef96e9b9b9f3ee1612f4beb0257
ready
fMRI-FC
ccf76ee04722df945c7c574a27b2da49fc63bef96e9b9b9f3ee1612f4beb0257
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "adhd_q007", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "adhd" } ]
In ABCD_DISC, excluding missing dx, do ADHD cases (dx=1.0) differ from controls (dx=0.0) in within-DorsalAttention connectivity (fc_fc_DorsAttn_DorsAttn_z), with no additional covariates, and is the difference replicated in ABCD_REP?
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ncb-scientific-ccf76ee04722df94
1d9d47d8fb3306553ad618d72cc1edd153c18a615ede16497517080992ffebab
ncb-sem-a78bc3d5c2482eab
adhd
[ "ncb21-task-217080e5d5d61690" ]
[ "ad_aging_q012" ]
aligned_with_safety_augmentation
ncb-scientific-ce5c0063d478e61d
scientific
ncb-claim-f3e4911f433998d2
{ "claim_id": "ad_aging_q012", "covariates": [ "sex", "eTIV", "site" ], "discovery_cohort": "ADNI_DISC", "estimand": { "direction": "negative", "group": null, "outcome": "smri_hippocampus", "predictor": "age", "region_set": null, "type": "association", "unit": "scalar" ...
ce5c0063d478e61da293889593af2afd1b8b29c77b2df5c7d7de1191d162c10c
ready
sMRI
ce5c0063d478e61da293889593af2afd1b8b29c77b2df5c7d7de1191d162c10c
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "ad_aging_q012", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "ad_aging" ...
In ADNI_DISC, among CN participants, is older age associated with lower smri_hippocampus, adjusting for sex?
3da394c3a30e23294013cccfc65037f96a4f2d8eed9a06c86cb73d751dff11e4
ncb-scientific-ce5c0063d478e61d
7d494c68bdd53df5e8e4d1696c6cb9570310dcc82fe9e3a9d5833d7ab948fbe5
ncb-sem-f3e4911f433998d2
ad_aging
[ "ncb21-task-b0061b835ca1457f" ]
[ "pubmed_36403658_pmid36403658_adhd_fc_classifier" ]
ambiguous_unresolved
ncb-scientific-ce9b34e85b1510c7
scientific
ncb-claim-9a49e748df2ba005
{ "claim_id": "pubmed_36403658_pmid36403658_adhd_fc_classifier", "covariates": [ "age", "sex", "site" ], "discovery_cohort": "ABCD_DISC", "estimand": { "direction": "two_sided", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "fc...
ce9b34e85b1510c7cdb61caab47224a564c4d18a9d89c72c6952a58e8ed87491
ambiguous_unresolved
fMRI-FC
ce9b34e85b1510c7cdb61caab47224a564c4d18a9d89c72c6952a58e8ed87491
[ { "prior_label": "candidate_unknown", "source_citation": "PMID:36403658; DOI:10.1016/j.neuropsychologia.2022.108418", "source_collection": "stage2_current", "source_id": "pubmed_36403658_pmid36403658_adhd_fc_classifier", "source_mode": "literature_grounded", "source_path": "review-stage/conf...
For literature-grounded healthy controls, social phobia without ADHD, and social phobia with ADHD comorbidity effect on multivariate classification using functional connectivity strength and topology features in resting-state fMRI functional connectivity, using ABCD as discovery and ADHD200 as replication, test the cla...
7421175b2096c21c0b5e64a0e0aa9d6b008eae9399f641013be99353c44e7791
ncb-scientific-ce9b34e85b1510c7
66697fc6f37b179f47e10d1343b50e3b136fcac39589669f21cad41afa9191c8
ncb-sem-9a49e748df2ba005
adhd
[]
[ "asd_q040" ]
aligned
ncb-scientific-cfe09363aec199e4
scientific
ncb-claim-a7e5d3c11d8415e9
{ "claim_id": "asd_q040", "covariates": [], "discovery_cohort": "ABIDE2_DISC", "estimand": { "direction": "two_sided", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "fc_fc_Cont_Default_z", "predictor": "confirm_dx", "region_set": nul...
cfe09363aec199e4d87cfd179508934aa0a694e2ac85f122d79bab05a56bf5ba
ready
fMRI-FC
cfe09363aec199e4d87cfd179508934aa0a694e2ac85f122d79bab05a56bf5ba
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "asd_q040", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "asd" } ]
In ABIDE2_DISC, with replication assessed in ABIDE2_REP, does fc_fc_Cont_Default_z differ between dx=1 and dx=2 participants using dx as the predictor and no additional covariates?
6a4dc9064b09c7072d2ebd1f18d158dd9de28db5c64f9b5312460d490e6899b0
ncb-scientific-cfe09363aec199e4
fe02b61f8be7f79c488b5f3c770fa296ca58555ba70789fce60ae7b50516eb18
ncb-sem-a7e5d3c11d8415e9
asd
[ "ncb21-task-e1c38e33b7e80abc" ]
[ "adhd_q017" ]
aligned_with_safety_augmentation
ncb-scientific-cff1d7d2ccfb4083
scientific
ncb-claim-431a40f2cc1f5ed6
{ "claim_id": "adhd_q017", "covariates": [ "age", "sex", "site" ], "discovery_cohort": "ADHD200_DISC", "estimand": { "direction": "two_sided", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "fc_fc_SalVentAttn_SomMot_z", "pre...
cff1d7d2ccfb4083777868ad19918ae7945541ba0eac4f51f5d045cb634efc6b
ready
fMRI-FC
cff1d7d2ccfb4083777868ad19918ae7945541ba0eac4f51f5d045cb634efc6b
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "adhd_q017", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "adhd" } ]
In ADHD200_DISC, is any ADHD diagnosis (dx in {1,2,3}) versus control (dx=0) associated with altered Salience/VentralAttention-Somatomotor connectivity (fc_fc_SalVentAttn_SomMot_z), with no additional covariates, and does this replicate in ADHD200_REP?
709e9febbf7abd25df4363a4d1182f95a9e3a8fa6210b3dcb398f946fc7bbe9f
ncb-scientific-cff1d7d2ccfb4083
5df824301ab1addd97daaf4023192f0090f63d68208b8c74686e168f40a67e43
ncb-sem-431a40f2cc1f5ed6
adhd
[ "ncb21-task-1ee6ff3275d5a6b2" ]
[ "psychosis_q039" ]
aligned
ncb-scientific-d0535a6cab6d913b
scientific
ncb-claim-6c35024a79091cc0
{ "claim_id": "psychosis_q039", "covariates": [], "discovery_cohort": "COBRE_DISC", "estimand": { "direction": "negative", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "fc_within_network", "predictor": "confirm_dx", "region_set": nu...
d0535a6cab6d913b7aae20a3c6e47c1d8b5c21a56abd87a6f45877adf81829e0
ready
fMRI-FC
d0535a6cab6d913b7aae20a3c6e47c1d8b5c21a56abd87a6f45877adf81829e0
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "psychosis_q039", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "psychosis...
Across COBRE_DISC and COBRE_REP, is the SZ-versus-HC contrast for fc_within_network directionally consistent with lower values in SZ in unadjusted dx-only comparisons with no covariates?
2865cc357ad9e78529f2933b956eeee50c62f939ff14b00077259b8823f0a7a9
ncb-scientific-d0535a6cab6d913b
edd521086383f67cc2d26e964127ebbf406e84c4db92d7bde5aa6226cc4c28a6
ncb-sem-6c35024a79091cc0
psychosis
[ "ncb21-task-dc81572c10516fb6" ]
[ "normative_fmri_024" ]
aligned_with_safety_augmentation
ncb-scientific-d0e3c2468afe4539
scientific
ncb-claim-2b84eedb776ad4bf
{ "claim_id": "normative_fmri_024", "covariates": [ "sex", "site", "phen_fluid_composite" ], "discovery_cohort": "HCP_Aging_DISC", "estimand": { "direction": "positive", "group": null, "outcome": "fc_fc_Default_DorsAttn_z", "predictor": "age", "region_set": null, "type": "a...
d0e3c2468afe45395a1d6887f96a757cb6cedbc19164247267f228b20c1f9067
ready
fMRI-FC
d0e3c2468afe45395a1d6887f96a757cb6cedbc19164247267f228b20c1f9067
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "normative_fmri_024", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "norma...
In HCP_Aging_DISC, with replication in HCP_Aging_REP, is higher age associated with higher default-mode to dorsal-attention connectivity (fc_fc_Default_DorsAttn_z), adjusting for sex and cognition?
ed9953899bc988a5e5009042c2578b4eece7c13e0340b2a414f84cb894ed3fb0
ncb-scientific-d0e3c2468afe4539
952d57058977fdd6613ea34b2dd45e721b3318e5eca7c0cd360552cc3ac9f42c
ncb-sem-2b84eedb776ad4bf
normative_fmri
[ "ncb21-task-d2e03b9aa3b48e11" ]
[ "adhd_q030" ]
aligned_with_safety_augmentation
ncb-scientific-d37402dd791a12dc
scientific
ncb-claim-b2165137d6f2cd98
{ "claim_id": "adhd_q030", "covariates": [ "age", "sex", "site" ], "discovery_cohort": "ABCD_DISC", "estimand": { "direction": "two_sided", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "fc_fc_DorsAttn_SalVentAttn_z", "pred...
d37402dd791a12dc5975c0b5a9fc0994be3d63826bdbf317c431e337efa54f61
ready
fMRI-FC
d37402dd791a12dc5975c0b5a9fc0994be3d63826bdbf317c431e337efa54f61
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "adhd_q030", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "adhd" } ]
In ABCD_DISC and ABCD_REP separately, excluding missing dx, is ADHD status (dx=1.0 vs dx=0.0) associated with altered DorsalAttention-Salience/VentralAttention connectivity (fc_fc_DorsAttn_SalVentAttn_z), with no additional covariates?
292a25ddcfeea37f416e546f540c64b17449babb3a50f8339797531ea860787d
ncb-scientific-d37402dd791a12dc
d003381a01bb233a9475b078649877a01efae6bfdb87a9fd8387c75a2a4c0fc4
ncb-sem-b2165137d6f2cd98
adhd
[ "ncb21-task-9e1aef9a7ecc24a2" ]
[ "asd_q019" ]
aligned_with_safety_augmentation
ncb-scientific-d3b9d78a966173c6
scientific
ncb-claim-ad2e72eb3441438a
{ "claim_id": "asd_q019", "covariates": [ "age", "sex", "site" ], "discovery_cohort": "ABIDE2_DISC", "estimand": { "direction": "two_sided", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "fc_fc_Default_DorsAttn", "predictor...
d3b9d78a966173c6a58a5b8ed01a0316ad73601092701d1310f08cee0928e62e
ready
fMRI-FC
d3b9d78a966173c6a58a5b8ed01a0316ad73601092701d1310f08cee0928e62e
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "asd_q019", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "asd" } ]
In ABIDE2_DISC, with replication assessed in ABIDE2_REP, does fc_fc_Default_DorsAttn differ between dx=1 and dx=2 participants using dx as the predictor and no additional covariates?
41065d358cb9078ccbb06422c2694f7cfad4dfbcfda49f6ca8be7b03e1235ffc
ncb-scientific-d3b9d78a966173c6
cdc0a3e3583d3137226e1f9d0fb6a7262fea7ce6e2b83140279b21a1c58830af
ncb-sem-ad2e72eb3441438a
asd
[ "ncb21-task-0aedc228888c5eae" ]
[ "psychosis_q011" ]
aligned_with_safety_augmentation
ncb-scientific-d4c0b42a60357a5d
scientific
ncb-claim-2166e66544e56e96
{ "claim_id": "psychosis_q011", "covariates": [ "age", "sex", "site" ], "discovery_cohort": "COBRE_DISC", "estimand": { "direction": "negative", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "fc_within_network", "predictor"...
d4c0b42a60357a5d939e12105a02798899968bed182f8471def699471bf39842
ready
fMRI-FC
d4c0b42a60357a5d939e12105a02798899968bed182f8471def699471bf39842
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "psychosis_q011", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "psychosis...
In COBRE_DISC, is fc_within_network lower in SZ than HC in an unadjusted group comparison with dx as the only predictor and no covariates?
268874f0caddc32a56475d579d3e315fac40387f7bec01ff2964398e0b3bf634
ncb-scientific-d4c0b42a60357a5d
edd521086383f67cc2d26e964127ebbf406e84c4db92d7bde5aa6226cc4c28a6
ncb-sem-2166e66544e56e96
psychosis
[ "ncb21-task-08c01f90e76c8f85" ]
[ "normative_fmri_036" ]
aligned_with_safety_augmentation
ncb-scientific-d6cbeb536d2b0163
scientific
ncb-claim-ce4cface1e4e8236
{ "claim_id": "normative_fmri_036", "covariates": [ "age", "sex", "site" ], "discovery_cohort": "ABCD_DISC", "estimand": { "direction": "positive", "group": null, "outcome": "fc_fc_Cont_Cont_z", "predictor": "phen_fluid_composite", "region_set": null, "type": "association",...
d6cbeb536d2b01632b3c753bd865bcb7f96749ca7f83705faf307f82a8ceda07
ready
fMRI-FC
d6cbeb536d2b01632b3c753bd865bcb7f96749ca7f83705faf307f82a8ceda07
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "normative_fmri_036", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "norma...
Among ABCD participants with dx=0.0, in ABCD_DISC with replication in ABCD_REP, is higher cognition associated with higher control-network within-network connectivity (fc_fc_Cont_Cont_z), adjusting for age and sex?
91db835974b0b3a4116f0ca5bfba75df642f5cb9e2df009aa224269244928cdc
ncb-scientific-d6cbeb536d2b0163
9e63074cf36234974e50a155d2a5a353103ad45fcf26453f76da5fd49fd71f89
ncb-sem-ce4cface1e4e8236
normative_fmri
[ "ncb21-task-a2cefcd7709126f7" ]
[ "sex_smri_hippocampus_gsp_adni_cn" ]
ambiguous_unresolved
ncb-scientific-da6e0b38e7772e80
scientific
ncb-claim-494b154ddee82225
{ "claim_id": "sex_smri_hippocampus_gsp_adni_cn", "covariates": [ "age", "eTIV", "site" ], "discovery_cohort": "GSP_DISC", "estimand": { "direction": "negative", "group": { "case": "F", "control": "M", "var": "sex" }, "outcome": "smri_hippocampus", "predictor"...
da6e0b38e7772e80aea1f58d4a4006eca8cf9c7e3bc872b5d952c3853da64503
ambiguous_unresolved
sMRI
da6e0b38e7772e80aea1f58d4a4006eca8cf9c7e3bc872b5d952c3853da64503
[ { "prior_label": "candidate_unknown", "source_citation": "Ritchie et al. 2018 Cerebral Cortex", "source_collection": "legacy_scientific", "source_id": "sex_smri_hippocampus_gsp_adni_cn", "source_mode": "literature", "source_path": "data/claims/fixed_literature_claims.csv", "target_family...
For sex difference in eTIV-adjusted hippocampal volume in sMRI, using GSP as discovery and ADNI_CN as replication, test the claim with expected direction female_minus_male negative on hippocampal volume after age and eTIV adjustment and adjust for age;eTIV when available.
de8e6e2d8702bb8a61de5ef970eb0a5e5d44b927e87b4e0cb09e7dfe01c3addf
ncb-scientific-da6e0b38e7772e80
380b875a6be20514906b9c85d046ada773bca97e0e441308690e6b146dc21455
ncb-sem-494b154ddee82225
normative_fmri
[]
[ "ad_aging_q013", "ad_aging_q015", "ad_aging_q019" ]
aligned_with_safety_augmentation
ncb-scientific-da99887ee1c161f8
scientific
ncb-claim-d22048e0b525ef58
{ "claim_id": "ad_aging_q013", "covariates": [ "age", "sex", "eTIV", "site" ], "discovery_cohort": "ADNI_DISC", "estimand": { "direction": "positive", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "pet_av45", "predictor...
da99887ee1c161f8ace824a8f4f353abd0b75b76e0f9cc87e3fdc1d6e2cca576
ready
PET
da99887ee1c161f8ace824a8f4f353abd0b75b76e0f9cc87e3fdc1d6e2cca576
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "ad_aging_q013", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "ad_aging" ...
In ADNI_DISC, with ADNI_REP as a replication cohort, is Dementia associated with higher pet_av45 than CN, adjusting for age and sex?
971e0ba85bd308439b4473e5b129c205065eb077bfa7cab7d9489fdd1bf8314e
ncb-scientific-da99887ee1c161f8
94b82c5a937c61645989e76a195386477c181f2c9fbd0b2ffa19373518d83fa7
ncb-sem-d22048e0b525ef58
ad_aging
[ "ncb21-task-b148816c3f2385a3" ]
[ "adhd_region_adhd200_abcd" ]
aligned
ncb-scientific-dc2d5ad4964bca96
scientific
ncb-claim-496f6200eab60252
{ "claim_id": "adhd_region_adhd200_abcd", "covariates": [ "age", "sex", "site" ], "discovery_cohort": "ADHD200_DISC", "estimand": { "direction": "two_sided", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "raw_fmri_region_", ...
dc2d5ad4964bca964b15ebb2637b5eba244814c6906a20b19cd600878ccb4570
ready
other
dc2d5ad4964bca964b15ebb2637b5eba244814c6906a20b19cd600878ccb4570
[ { "prior_label": "fragile", "source_citation": "ADHD-200 Consortium 2012", "source_collection": "legacy_scientific", "source_id": "adhd_region_adhd200_abcd", "source_mode": "literature", "source_path": "data/claims/fixed_literature_claims.csv", "target_family": "adhd" } ]
For ADHD case-control fMRI regional difference in fMRI-region, using ADHD200 as discovery and ABCD as replication, test the claim with expected direction two_sided and adjust for age;sex;site when available.
dec4f932dce09d7f95e9a3046349bbb5c55fa66e864f0c7511751744056b91ee
ncb-scientific-dc2d5ad4964bca96
b1a4f6639fe27d228938bad44ad8f448065650677f948f3c70dce5dd7206482f
ncb-sem-496f6200eab60252
adhd
[ "ncb21-task-d568db2d613cee3b" ]
[ "normative_fmri_003" ]
aligned_with_safety_augmentation
ncb-scientific-dc6371e72c01cdcd
scientific
ncb-claim-8552739e6f8398cb
{ "claim_id": "normative_fmri_003", "covariates": [ "sex", "phen_fluid_intelligence", "site" ], "discovery_cohort": "UKB_DISC", "estimand": { "direction": "negative", "group": null, "outcome": "fc_fc_DorsAttn_DorsAttn_z", "predictor": "age", "region_set": null, "type": "ass...
dc6371e72c01cdcd2e2e176efc8496ba66d5715ea1c8da75ab66be1c67032e07
ready
fMRI-FC
dc6371e72c01cdcd2e2e176efc8496ba66d5715ea1c8da75ab66be1c67032e07
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "normative_fmri_003", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "norma...
In UKB_DISC, with replication in UKB_REP, is higher age associated with lower dorsal-attention within-network connectivity (fc_fc_DorsAttn_DorsAttn_z), adjusting for sex and cognition?
8c7268efc7fdbae0da49e6d66facb791887c6cceb3e2dc9d1340e6323742f628
ncb-scientific-dc6371e72c01cdcd
29c6f26014b07b4736b3860f8cb982ec0fd44c210b69ceabcee72a1d5ce47045
ncb-sem-8552739e6f8398cb
normative_fmri
[ "ncb21-task-59318963ec862829" ]
[ "pubmed_35338900_pmid35338900_boysadhd_limbicdmn" ]
aligned
ncb-scientific-de1363fa0a54a318
scientific
ncb-claim-22c65198c6a302be
{ "claim_id": "pubmed_35338900_pmid35338900_boysadhd_limbicdmn", "covariates": [ "age", "sex", "site" ], "discovery_cohort": "ABCD_DISC", "estimand": { "direction": "positive", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "fc_...
de1363fa0a54a31857453e1dd873734715696b750931e1ee29d64fb8103b2e58
ready
fMRI-FC
de1363fa0a54a31857453e1dd873734715696b750931e1ee29d64fb8103b2e58
[ { "prior_label": "candidate_unknown", "source_citation": "PMID:35338900; DOI:10.1016/j.dcn.2022.101101", "source_collection": "stage2_current", "source_id": "pubmed_35338900_pmid35338900_boysadhd_limbicdmn", "source_mode": "literature_grounded", "source_path": "review-stage/confirm-gates-all...
For literature-grounded boys with ADHD / ADHD-by-sex group contrast effect on frontal-limbic striatum connectivity with default mode network regions in fMRI-FC, using ABCD as discovery and ADHD200 as replication, test the claim with expected direction positive and adjust for age;sex;site when available.
a866e8fbfb0b9b2be4c550835cb012680627589fd242f70ba3ad9864d827bd3f
ncb-scientific-de1363fa0a54a318
f8bdf3c57e6489f08c59b2722098f4fb25d03ddbfe03f62e417ac563efd6067c
ncb-sem-22c65198c6a302be
adhd
[ "ncb21-task-9e56ed379ff23dcc" ]
[ "ad_aging_q014", "ad_aging_q016", "ad_aging_q020", "fdg_pet_adni" ]
aligned_with_safety_augmentation
ncb-scientific-de319955c8826c8c
scientific
ncb-claim-cf0eadfce7fc0fa3
{ "claim_id": "ad_aging_q014", "covariates": [ "age", "sex", "eTIV", "site" ], "discovery_cohort": "ADNI_DISC", "estimand": { "direction": "negative", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "pet_fdg_suvr", "predi...
de319955c8826c8c592a65c22c0905af5cc82a9b10dc096639a3311f2ecb2566
ready
PET
de319955c8826c8c592a65c22c0905af5cc82a9b10dc096639a3311f2ecb2566
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "ad_aging_q014", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "ad_aging" ...
In ADNI_DISC, with ADNI_REP as a replication cohort, is Dementia associated with lower pet_fdg_suvr than CN, adjusting for age and sex?
5db8d4e002994920469c6c5dd0a369acbc70ebc9f769e6bda9991d7427d86cc3
ncb-scientific-de319955c8826c8c
331c26efa5688b437e6263e8f8e0a90dfcd67164a28ad459d05962ee91067e36
ncb-sem-cf0eadfce7fc0fa3
ad_aging
[ "ncb21-task-73b0d28461d6f903" ]
[ "ad_aging_q023" ]
aligned_with_safety_augmentation
ncb-scientific-e035748f4f603bb4
scientific
ncb-claim-799ee41494ce841f
{ "claim_id": "ad_aging_q023", "covariates": [ "age", "sex", "eTIV", "site" ], "discovery_cohort": "OASIS3_DISC", "estimand": { "direction": "positive", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "smri_ventricles", "...
e035748f4f603bb4a9823928fecfe37e85d40785b688ac68eaeab6eaeba5a41c
ready
sMRI
e035748f4f603bb4a9823928fecfe37e85d40785b688ac68eaeab6eaeba5a41c
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "ad_aging_q023", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "ad_aging" ...
In OASIS3_DISC, with OASIS3_REP as a replication cohort, is Dementia associated with higher smri_ventricles than CN, adjusting for age and sex?
dda4d17383460b6399844e0b82686aefbcdba515e616f329a1d60f404e97ff24
ncb-scientific-e035748f4f603bb4
ca6200f8d7f0001b7332edb36df1554a0921d126a93cb5c107288257e312eeae
ncb-sem-799ee41494ce841f
ad_aging
[ "ncb21-task-6312b91e545f9c34" ]
[ "normative_fmri_015" ]
aligned_with_safety_augmentation
ncb-scientific-e1c33335981addda
scientific
ncb-claim-b478bca2f871dfa1
{ "claim_id": "normative_fmri_015", "covariates": [ "age", "sex", "site" ], "discovery_cohort": "HCP_DISC", "estimand": { "direction": "positive", "group": null, "outcome": "fc_fc_Cont_DorsAttn_z", "predictor": "phen_fluid_composite", "region_set": null, "type": "associatio...
e1c33335981addda2599fe24aa86c62ac3f0c9a159ee7345d23c83e540683619
ready
fMRI-FC
e1c33335981addda2599fe24aa86c62ac3f0c9a159ee7345d23c83e540683619
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "normative_fmri_015", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "norma...
In HCP_DISC, with replication in HCP_REP, is higher cognition associated with higher connectivity between control and dorsal-attention networks (fc_fc_Cont_DorsAttn_z), adjusting for age and sex?
01601d6c8e794ea44c5f1de28b174d9bfce919be7b20f2ca4280c4a8b454c7df
ncb-scientific-e1c33335981addda
3d7e1a9c383275f414c963af54d9cfa3bac5b7886c72d2c5aa521b977e7110c0
ncb-sem-b478bca2f871dfa1
normative_fmri
[ "ncb21-task-cc16390eeb98c9fe" ]
[ "pubmed_1431963_pmid1431963_mta_ad_vs_controls", "pubmed_21729419_pmid21729419_2" ]
aligned
ncb-scientific-e2c8b315d5871123
scientific
ncb-claim-d384989302daa852
{ "claim_id": "pubmed_1431963_pmid1431963_mta_ad_vs_controls", "covariates": [ "age", "eTIV", "sex" ], "discovery_cohort": "ADNI_DISC", "estimand": { "direction": "positive", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "smri_...
e2c8b315d58711232df3fb244f289b13f1a98c97f3043bbed5db37f77d0fac0a
ready
sMRI
e2c8b315d58711232df3fb244f289b13f1a98c97f3043bbed5db37f77d0fac0a
[ { "prior_label": "candidate_unknown", "source_citation": "PMID:1431963; DOI:10.1136/jnnp.55.10.967", "source_collection": "stage2_current", "source_id": "pubmed_1431963_pmid1431963_mta_ad_vs_controls", "source_mode": "literature_grounded", "source_path": "review-stage/confirm-gates-all-gpt55...
For literature-grounded probable Alzheimer's disease versus age-matched controls effect on medial temporal lobe atrophy in sMRI, using ADNI as discovery and OASIS3 as replication, test the claim with expected direction positive and adjust for age;eTIV;sex when available.
2dc53034714df0fa1117c19b6bafccdebd2c66d63922f71e3c8a2cbbbc21493f
ncb-scientific-e2c8b315d5871123
7d1c83104741ed5b01b697d5a8021cc56dc98cc9628d8a91ecc6fa7ccc42c567
ncb-sem-d384989302daa852
ad_aging
[ "ncb21-task-8efc33f2fd8e4854" ]
[ "psychosis_q036" ]
aligned
ncb-scientific-e313edffc6da7a07
scientific
ncb-claim-2ccad72c3141229c
{ "claim_id": "psychosis_q036", "covariates": [], "discovery_cohort": "BSNIP2_DISC", "estimand": { "direction": "two_sided", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "fc_between_network", "predictor": "confirm_dx", "region_set":...
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ready
fMRI-FC
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[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "psychosis_q036", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "psychosis...
Across BSNIP2_DISC and BSNIP2_REP, is the SZ-versus-HC contrast for fc_between_network directionally consistent in unadjusted dx-only comparisons with no covariates?
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ncb-scientific-e313edffc6da7a07
f555ea3e77e68e7c98be57a506ff641953f2f8e879082a91e5d6b59613b497bb
ncb-sem-2ccad72c3141229c
psychosis
[ "ncb21-task-9bf0eb30f9254c4a" ]
[ "psychosis_q026" ]
aligned_with_safety_augmentation
ncb-scientific-e43def8c3b8cb4e9
scientific
ncb-claim-893ac2c9b485762f
{ "claim_id": "psychosis_q026", "covariates": [ "age", "sex", "site" ], "discovery_cohort": "FBIRN_DISC", "estimand": { "direction": "two_sided", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "fc_mean_abs", "predictor": "co...
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ready
fMRI-FC
e43def8c3b8cb4e9401abd45c8e585ca3fb7555ed77364cdacf981560d643998
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "psychosis_q026", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "psychosis...
In FBIRN_DISC, do SZ participants differ from HC participants in fc_mean_abs in an unadjusted comparison using dx as the only predictor and no covariates?
e99e3b5e8064869b751e6cda75c26be803b602132104ce8ce51c4d5fd60cf459
ncb-scientific-e43def8c3b8cb4e9
55037708c84a264715f67a9d65743dd29b7ae0b6c38b838b4c18430c1c6ed8d1
ncb-sem-893ac2c9b485762f
psychosis
[ "ncb21-task-57b20f6c2d349598" ]
[ "ad_hippocampal_atrophy_adni_oasis3" ]
aligned
ncb-scientific-e59458cf873b37f4
scientific
ncb-claim-9a1d0e71271e5380
{ "claim_id": "ad_hippocampal_atrophy_adni_oasis3", "covariates": [ "age", "sex", "eTIV" ], "discovery_cohort": "ADNI_DISC", "estimand": { "direction": "negative", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "smri_hippocampus...
e59458cf873b37f444e003d8a14a9e20dcedbee238f1b165ec909b1e8b57abe8
ready
sMRI
e59458cf873b37f444e003d8a14a9e20dcedbee238f1b165ec909b1e8b57abe8
[ { "prior_label": "known_positive", "source_citation": "Jack et al. 2018 NIA-AA framework", "source_collection": "legacy_scientific", "source_id": "ad_hippocampal_atrophy_adni_oasis3", "source_mode": "literature", "source_path": "data/claims/fixed_literature_claims.csv", "target_family": ...
For AD hippocampal atrophy in sMRI, using ADNI as discovery and OASIS3 as replication, test the claim with expected direction negative and adjust for age;sex;eTIV when available.
a272797c98c16f6bad72d38eec4f74a57ed3e8a0d23d4f4f052e1e48be3f5b38
ncb-scientific-e59458cf873b37f4
d0b6b8c219d458c68ca3b6a197245ee4d8a65b4b971488d03ed6e84eff5bf700
ncb-sem-9a1d0e71271e5380
ad_aging
[ "ncb21-task-c2ee1c5133d1ee46" ]
[ "pubmed_37121277_pmid37121277_reho_cluster1_vs_td" ]
ambiguous_unresolved
ncb-scientific-e59b8563fe5abace
scientific
ncb-claim-f061463e8148d412
{ "claim_id": "pubmed_37121277_pmid37121277_reho_cluster1_vs_td", "covariates": [ "age", "sex", "site" ], "discovery_cohort": "ABIDE2_DISC", "estimand": { "direction": "positive", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "...
e59b8563fe5abace75c175eff2d6c6bc371d7aa0b5053b5fc34317818314bff5
ambiguous_unresolved
fMRI-FC
e59b8563fe5abace75c175eff2d6c6bc371d7aa0b5053b5fc34317818314bff5
[ { "prior_label": "candidate_unknown", "source_citation": "PMID:37121277; DOI:10.1016/j.bbr.2023.114458", "source_collection": "stage2_current", "source_id": "pubmed_37121277_pmid37121277_reho_cluster1_vs_td", "source_mode": "literature_grounded", "source_path": "review-stage/confirm-gates-al...
For literature-grounded ASD Cluster-1 with more severe ADI-R impairment versus typical-development controls effect on local functional connectivity assessed by regional homogeneity (ReHo) in resting-state fMRI functional connectivity, using ABIDE2 as discovery and ABIDE2 as replication, test the claim with expected dir...
a0d5dc5438c98c44a1142f800a20e275315469c928a99f6281c6989b351bde30
ncb-scientific-e59b8563fe5abace
8c1bb7b19f0352d10ec38ab73babf6b56ce4313e7ee75776fb5b0209b475d64d
ncb-sem-f061463e8148d412
asd
[]
[ "asd_q009" ]
ambiguous_unresolved
ncb-scientific-e59e508b9cc05116
scientific
ncb-claim-dfee12a2936ad2e1
{ "claim_id": "asd_q009", "covariates": [ "age", "sex", "site" ], "discovery_cohort": "ABIDE1_DISC", "estimand": { "direction": "negative", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": [ "fc_within_network", "fc_be...
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ambiguous_unresolved
fMRI-FC
e59e508b9cc05116c4cf470f0f1a2f388a2f1589d7452ef3d8199026639608ba
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "asd_q009", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "asd" } ]
Across ABIDE1_DISC and ABIDE1_REP, is the ASD-minus-HC contrast more negative for fc_within_network than for fc_between_network, using dx as the predictor and no additional covariates?
797bbdaba8a4df5f341b4176fbaaef53ec9115a5458dcaa007d026f6c9a3224a
ncb-scientific-e59e508b9cc05116
a2e79e2c1d0775960adda10521fbe330e49d35826cdbf605c2a536915fc84fe5
ncb-sem-dfee12a2936ad2e1
asd
[]
[ "psychosis_q007" ]
aligned
ncb-scientific-e5b2412738b16335
scientific
ncb-claim-6c35024a79091cc0
{ "claim_id": "psychosis_q007", "covariates": [], "discovery_cohort": "BSNIP2_REP", "estimand": { "direction": "negative", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "fc_within_network", "predictor": "confirm_dx", "region_set": nu...
e5b2412738b16335f55b1518f3aac394c8cfff48e1b39a9dc0d2b64c2cbb5877
ready
fMRI-FC
e5b2412738b16335f55b1518f3aac394c8cfff48e1b39a9dc0d2b64c2cbb5877
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "psychosis_q007", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "psychosis...
In BSNIP2_REP, is fc_within_network lower in SZ than HC in an unadjusted dx-only group comparison with no covariates?
6be75917f0e2f16e42737a15e1d03b83801e2cfd0f7880fd0c744de4b4194bea
ncb-scientific-e5b2412738b16335
56c782efac5ece982421f6cc450e0a71823dbb420d4309f34cf0bab1b9426b92
ncb-sem-6c35024a79091cc0
psychosis
[ "ncb21-task-90944d2b4886bb16" ]
[ "pubmed_34649002_pmid34649002_brainage_attnwm" ]
ambiguous_unresolved
ncb-scientific-e5be6d84f8e872b5
scientific
ncb-claim-34e75ab9f2a20a94
{ "claim_id": "pubmed_34649002_pmid34649002_brainage_attnwm", "covariates": [ "age", "sex", "eTIV" ], "discovery_cohort": "ADNI_DISC", "estimand": { "direction": "positive", "group": null, "outcome": "smri_ventricles", "predictor": "beh_cdrsb", "region_set": null, "type": "...
e5be6d84f8e872b5e5382923d529f5e638a49c79635afdd5fd90ca94bee033c0
ambiguous_unresolved
sMRI
e5be6d84f8e872b5e5382923d529f5e638a49c79635afdd5fd90ca94bee033c0
[ { "prior_label": "candidate_unknown", "source_citation": "PMID:34649002; DOI:10.1016/j.neurobiolaging.2021.08.020", "source_collection": "stage2_current", "source_id": "pubmed_34649002_pmid34649002_brainage_attnwm", "source_mode": "literature_grounded", "source_path": "review-stage/confirm-g...
For literature-grounded Advanced brain age / higher atrophy-based brain age estimate effect on domain-specific cognitive impairment: attention and working memory in structural MRI-derived brain age estimate with neuropsychological test outcomes, using ADNI as discovery and OASIS3 as replication, test the claim with exp...
b9a5084e40ed136453fa78c607c671d831a7a96ce87ec65562822389ffcb59b6
ncb-scientific-e5be6d84f8e872b5
cc157d8a039957a9d7571c621a576b2d41a942573356bb18b8eee9e856ba5638
ncb-sem-34e75ab9f2a20a94
ad_aging
[]
[ "adhd_q038" ]
aligned_with_safety_augmentation
ncb-scientific-e61ccc72bef4061c
scientific
ncb-claim-b32f9eea34f48563
{ "claim_id": "adhd_q038", "covariates": [ "age", "sex", "site" ], "discovery_cohort": "ADHD200_DISC", "estimand": { "direction": "two_sided", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "fc_fc_DorsAttn_SalVentAttn_z", "p...
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ready
fMRI-FC
e61ccc72bef4061ce3d466c68b9f2898acb4cf373aa0cdf600d200efef581b25
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "adhd_q038", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "adhd" } ]
In ADHD200_DISC and ADHD200_REP separately, is any ADHD diagnosis (dx in {1,2,3}) versus control (dx=0) associated with altered DorsalAttention-Salience/VentralAttention connectivity (fc_fc_DorsAttn_SalVentAttn_z), with no additional covariates?
72f823cd6727d3ca2473646d2fb99d420fad17685fc7a0dd7051f9255cb79731
ncb-scientific-e61ccc72bef4061c
bcbc62719dc9cf8604e9902e4891a802b961a32646ed29162c019a1eb6c975d4
ncb-sem-b32f9eea34f48563
adhd
[ "ncb21-task-8f7b785586ca8640" ]
[ "adhd_q002" ]
aligned_with_safety_augmentation
ncb-scientific-e655e7f3059cc2a2
scientific
ncb-claim-b9ed4cced1a322ad
{ "claim_id": "adhd_q002", "covariates": [ "age", "sex", "site" ], "discovery_cohort": "ABCD_DISC", "estimand": { "direction": "positive", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "fc_fc_Default_SalVentAttn_z", "predic...
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ready
fMRI-FC
e655e7f3059cc2a2fa0bfd47f5738215071ffd1c322d56face875667b06330b8
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "adhd_q002", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "adhd" } ]
In ABCD_DISC, excluding missing dx, is ADHD status (dx=1.0 vs dx=0.0) associated with higher Default-Salience/VentralAttention connectivity (fc_fc_Default_SalVentAttn_z), with no additional covariates, and is this replicated in ABCD_REP?
ca9d65dbe55f436643649c8b8bcfd65890cffe115c655917bc60e7333a44fd48
ncb-scientific-e655e7f3059cc2a2
158fa35591c0432d6f39d69fb2b847f7bbbbebe5dfc9c30f7b1e3824d1070c28
ncb-sem-b9ed4cced1a322ad
adhd
[ "ncb21-task-20579a56de42c261" ]
[ "normative_fmri_009" ]
aligned_with_safety_augmentation
ncb-scientific-e7c94f56c83e0651
scientific
ncb-claim-1ccf84c3360dce0e
{ "claim_id": "normative_fmri_009", "covariates": [ "sex", "phen_fluid_intelligence", "site" ], "discovery_cohort": "UKB_DISC", "estimand": { "direction": "negative", "group": null, "outcome": "fc_fc_Cont_DorsAttn_z", "predictor": "age", "region_set": null, "type": "associa...
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ready
fMRI-FC
e7c94f56c83e06518cfb23793f51ccaf963a39435caaaca93bcd7d7166f65091
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "normative_fmri_009", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "norma...
In UKB_DISC, with replication in UKB_REP, is higher age associated with lower connectivity between control and dorsal-attention networks (fc_fc_Cont_DorsAttn_z), adjusting for sex and cognition?
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ncb-scientific-e7c94f56c83e0651
63f0db688ca1d92f74aa49033266babd73d0ae161097ee8b6fa86d1e494cdc26
ncb-sem-1ccf84c3360dce0e
normative_fmri
[ "ncb21-task-2f2394534763a048" ]
[ "normative_fmri_017" ]
aligned_with_safety_augmentation
ncb-scientific-e9887ba0003df877
scientific
ncb-claim-96e4627e73973fdd
{ "claim_id": "normative_fmri_017", "covariates": [ "age", "sex", "site" ], "discovery_cohort": "HCP_DISC", "estimand": { "direction": "negative", "group": null, "outcome": "fc_fc_Default_DorsAttn_z", "predictor": "phen_fluid_composite", "region_set": null, "type": "associa...
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ready
fMRI-FC
e9887ba0003df8779438a68d1005ebb55b6bb49af3d222c23f2ed43541800f4c
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "normative_fmri_017", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "norma...
In HCP_DISC, with replication in HCP_REP, is higher cognition associated with lower default-mode to dorsal-attention connectivity (fc_fc_Default_DorsAttn_z), adjusting for age and sex?
3e12a2df79028cbe48db6c4236b5c390a09a342a63a4f34fa14467293b3b627e
ncb-scientific-e9887ba0003df877
b127f87ad91fdaf97401260450621a35f3f055164aecb4bd920490f8d92c454e
ncb-sem-96e4627e73973fdd
normative_fmri
[ "ncb21-task-402fa353a875fc7b" ]
[ "normative_fmri_041" ]
ambiguous_unresolved
ncb-scientific-ea3fb846fbd7533c
scientific
ncb-claim-a222e6184df9ba42
{ "claim_id": "normative_fmri_041", "covariates": [ "sex", "site" ], "discovery_cohort": "UKB_DISC", "estimand": { "direction": "negative", "group": null, "outcome": "fc_fc_Default_Default_z", "predictor": "age", "region_set": null, "type": "association", "unit": "scalar" ...
ea3fb846fbd7533c676dd161a54428494426f0c6824d09709a81fa30f338b633
ambiguous_unresolved
fMRI-FC
ea3fb846fbd7533c676dd161a54428494426f0c6824d09709a81fa30f338b633
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "normative_fmri_041", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "norma...
Across UKB_DISC and HCP_Aging_DISC, with replication in UKB_REP and HCP_Aging_REP, is higher age consistently associated with lower default-mode within-network connectivity (fc_fc_Default_Default_z), adjusting for sex and cognition within each cohort?
58c90ab3b1b58510e5f0f2e13a5ab7ffabf7d0e4ebd75ae723f93edf8f967540
ncb-scientific-ea3fb846fbd7533c
d7029f9ce196357e229c24544df53459cab44c8e0da98d54b1e0ec5b5d0bff01
ncb-sem-a222e6184df9ba42
normative_fmri
[]
[ "pubmed_32726311_pmid32726311_ifg_frontal_aging" ]
aligned
ncb-scientific-ea89da536ec1b952
scientific
ncb-claim-aeb1c8786cf64f4a
{ "claim_id": "pubmed_32726311_pmid32726311_ifg_frontal_aging", "covariates": [ "sex", "eTIV" ], "discovery_cohort": "ADNI_DISC", "estimand": { "direction": "two_sided", "group": null, "outcome": "smri_", "predictor": "age", "region_set": "shared_smri_regions", "type": "associa...
ea89da536ec1b9523290c286e989068afe29a58a5825ceed6c08a9a34eef20b7
ready
sMRI
ea89da536ec1b9523290c286e989068afe29a58a5825ceed6c08a9a34eef20b7
[ { "prior_label": "candidate_unknown", "source_citation": "PMID:32726311; DOI:10.1371/journal.pone.0234255", "source_collection": "stage2_current", "source_id": "pubmed_32726311_pmid32726311_ifg_frontal_aging", "source_mode": "literature_grounded", "source_path": "review-stage/confirm-gates-a...
For literature-grounded Older age among cognitively normal adults effect on Frontal cortical age-related MRI vulnerability in combined functional-structural MRI in the primary study; structural MRI in secondary analyses, using ADNI as discovery and OASIS3 as replication, test the claim with expected direction two_sided...
6b7f33fa135989223044e274d00845de44d612c47a671cf1f92e228a9ed89744
ncb-scientific-ea89da536ec1b952
65b82cc6f32bf0a28831d3f887183197356f67366cc360de9482ca1a68f700da
ncb-sem-aeb1c8786cf64f4a
ad_aging
[ "ncb21-task-5f5526a5d9758b26" ]
[ "normative_fmri_034" ]
aligned_with_safety_augmentation
ncb-scientific-eafa675a2857a0cb
scientific
ncb-claim-e8daa2d64f6a02a9
{ "claim_id": "normative_fmri_034", "covariates": [ "sex", "phen_fluid_composite", "site" ], "discovery_cohort": "ABCD_DISC", "estimand": { "direction": "positive", "group": null, "outcome": "fc_fc_Default_Default_z", "predictor": "age", "region_set": null, "type": "associa...
eafa675a2857a0cb78b9514e4388964a9404eeef0cb89fc7b7b10da646cce92b
ready
fMRI-FC
eafa675a2857a0cb78b9514e4388964a9404eeef0cb89fc7b7b10da646cce92b
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "normative_fmri_034", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "norma...
Among ABCD participants with dx=0.0, in ABCD_DISC with replication in ABCD_REP, is higher age associated with higher default-mode within-network connectivity (fc_fc_Default_Default_z), adjusting for sex and cognition?
c59ac3b2e7a124a06b2fa9fe10622c08911f9c0facc354f62cbeee13f85f9539
ncb-scientific-eafa675a2857a0cb
7e6f3a8cbcbdf17c40b7875edb746f4ddcd5d13ac201521f69934bc26f35be28
ncb-sem-e8daa2d64f6a02a9
normative_fmri
[ "ncb21-task-f88dd656c19b1fdc" ]
[ "age_region_ukb_hcpa" ]
ambiguous_unresolved
ncb-scientific-ebc1946b08c8a231
scientific
ncb-claim-9190f08063b9b655
{ "claim_id": "age_region_ukb_hcpa", "covariates": [ "sex", "site" ], "discovery_cohort": "UKB_DISC", "estimand": { "direction": "two_sided", "group": null, "outcome": "fc_fc_", "predictor": "age", "region_set": "fMRI_FC", "type": "association", "unit": "brainwide" }, "...
ebc1946b08c8a23166f5fc2fed19abc2a85446acc94e0efa1a061866cde9599d
ambiguous_unresolved
fMRI-FC
ebc1946b08c8a23166f5fc2fed19abc2a85446acc94e0efa1a061866cde9599d
[ { "prior_label": "candidate_unknown", "source_citation": "Fjell and Walhovd 2010 review [VERIFY]", "source_collection": "legacy_scientific", "source_id": "age_region_ukb_hcpa", "source_mode": "literature", "source_path": "data/claims/fixed_literature_claims.csv", "target_family": "normat...
For age association with fMRI regional descriptors in fMRI-region, using UKB as discovery and HCP_Aging as replication, test the claim with expected direction two_sided and adjust for sex;site when available.
e0da5f7b1cdb21ef0765b094a4c944b1064cf3d5f2d604b45dcb1a512b99b24e
ncb-scientific-ebc1946b08c8a231
c9a5638a01a983bf4a2b6eb4f0d087322e38c2b24a647d7bc107dbd06029f339
ncb-sem-9190f08063b9b655
normative_fmri
[]
[ "cobre_sz_clinical" ]
aligned_with_safety_augmentation
ncb-scientific-ec6d0cdd670ee6f6
scientific
ncb-claim-9086d74191ad7d9b
{ "claim_id": "cobre_sz_clinical", "covariates": [ "age", "sex", "site" ], "discovery_cohort": "COBRE_DISC", "estimand": { "direction": "two_sided", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "fc_", "predictor": "confirm...
ec6d0cdd670ee6f647b9d7beb7a19415bd2f41ceeb82613f17a2f3f0fdaefbd5
ready
fMRI-FC
ec6d0cdd670ee6f647b9d7beb7a19415bd2f41ceeb82613f17a2f3f0fdaefbd5
[ { "prior_label": "candidate_unknown", "source_citation": "[VERIFY]", "source_collection": "legacy_scientific", "source_id": "cobre_sz_clinical", "source_mode": "literature", "source_path": "data/claims/fixed_literature_claims.csv", "target_family": "psychosis" } ]
For schizophrenia clinical anchor in psychosis, using COBRE as discovery and FBIRN/SZ_JH as replication, test the claim with expected direction two_sided and adjust for age;sex when available.
10685a7400f926e4fa739e217543cee70f5a9bbac376fd29256dcca75c636c8b
ncb-scientific-ec6d0cdd670ee6f6
93a5ad352c27f2ec6bce80c18c9672ca185b5955d003fb67c4338614d22b063a
ncb-sem-9086d74191ad7d9b
psychosis
[ "ncb21-task-2f3eeb38f5c0d7d2" ]
[ "psychosis_q048" ]
aligned
ncb-scientific-ed8eabb252714493
scientific
ncb-claim-2ccad72c3141229c
{ "claim_id": "psychosis_q048", "covariates": [], "discovery_cohort": "FBIRN_DISC", "estimand": { "direction": "two_sided", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "fc_between_network", "predictor": "confirm_dx", "region_set": ...
ed8eabb252714493617a23875b640f41f1af8d9b8826cdbb8845c317adcbc72f
ready
fMRI-FC
ed8eabb252714493617a23875b640f41f1af8d9b8826cdbb8845c317adcbc72f
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "psychosis_q048", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "psychosis...
Across FBIRN_DISC and FBIRN_REP, is the SZ-versus-HC contrast for fc_between_network directionally consistent in unadjusted dx-only group comparisons with no covariates?
b07f572602f33554042fa619304fc36928b16e01f1e6621a082cef58280e951e
ncb-scientific-ed8eabb252714493
4b1e50cc2a3c73af7604895fc456c4766a2f11d590578051e8437843213b29c5
ncb-sem-2ccad72c3141229c
psychosis
[ "ncb21-task-bdd3e3934c5e73da" ]
[ "age_fc_hcpa_hcp" ]
aligned
ncb-scientific-edbf888496455e86
scientific
ncb-claim-6305924d5026f905
{ "claim_id": "age_fc_hcpa_hcp", "covariates": [ "sex", "site" ], "discovery_cohort": "HCP_Aging_DISC", "estimand": { "direction": "two_sided", "group": null, "outcome": "fc_fc_", "predictor": "age", "region_set": "functional_connectivity_network_pairs", "type": "association", ...
edbf888496455e861ca8f5b54407ebb0720d395cc740207187e5a05b344ee94d
ready
fMRI-FC
edbf888496455e861ca8f5b54407ebb0720d395cc740207187e5a05b344ee94d
[ { "prior_label": "candidate_unknown", "source_citation": "Fjell and Walhovd 2010 review [VERIFY]", "source_collection": "legacy_scientific", "source_id": "age_fc_hcpa_hcp", "source_mode": "literature", "source_path": "data/claims/fixed_literature_claims.csv", "target_family": "normative_...
For age association with FC descriptors in fMRI-FC, using HCP_Aging as discovery and HCP as replication, test the claim with expected direction two_sided and adjust for sex;site when available.
c91a1d8d790ef4f8e2f064c3a063a9b44d1ef63fe96e18322fae821da3307c10
ncb-scientific-edbf888496455e86
b76e204b70991970eca86f50791d7245ce8683e0af48d559573132b582ab00b7
ncb-sem-6305924d5026f905
normative_fmri
[ "ncb21-task-f6c946fca489fd62" ]
[ "normative_fmri_025" ]
aligned_with_safety_augmentation
ncb-scientific-ee627d7a5d823df0
scientific
ncb-claim-e297b93c7c7c4209
{ "claim_id": "normative_fmri_025", "covariates": [ "sex", "phen_fluid_composite", "site" ], "discovery_cohort": "HCP_Aging_DISC", "estimand": { "direction": "negative", "group": null, "outcome": "fc_fc_Vis_Vis_z", "predictor": "age", "region_set": null, "type": "associatio...
ee627d7a5d823df05e627bdf39c5c62a61d74c6453f8c490dc39a233a4ecf6a1
ready
fMRI-FC
ee627d7a5d823df05e627bdf39c5c62a61d74c6453f8c490dc39a233a4ecf6a1
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "normative_fmri_025", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "norma...
In HCP_Aging_DISC, with replication in HCP_Aging_REP, is higher age associated with lower visual-network within-network connectivity (fc_fc_Vis_Vis_z), adjusting for sex and cognition?
e8a90461e74ec7ea6bd2848fdbda5621c505143c5489c8da0aa3baa02a292dfd
ncb-scientific-ee627d7a5d823df0
8249688c6f2a3bf2ee6318ee1ece4a74e701ea1dee3f6653a9ca51127321ac8f
ncb-sem-e297b93c7c7c4209
normative_fmri
[ "ncb21-task-a054e2f3a1e18f45" ]
[ "psychosis_q014" ]
aligned
ncb-scientific-f0173ff72ee52b5e
scientific
ncb-claim-b158ae5ae8b91424
{ "claim_id": "psychosis_q014", "covariates": [], "discovery_cohort": "COBRE_REP", "estimand": { "direction": "two_sided", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "fc_mean_abs", "predictor": "confirm_dx", "region_set": null, ...
f0173ff72ee52b5e1e878ad93b6ab55443639c37100b7a6ff8546daeb9de844a
ready
fMRI-FC
f0173ff72ee52b5e1e878ad93b6ab55443639c37100b7a6ff8546daeb9de844a
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "psychosis_q014", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "psychosis...
In COBRE_REP, do SZ participants differ from HC participants in fc_mean_abs in an unadjusted group comparison with dx as the only predictor and no covariates?
727aacf9fe25bf3b193335f1517a20babb88aca9c9c33dd33dc6aa2a792769e7
ncb-scientific-f0173ff72ee52b5e
8aa9fa2f3e64d149a660298ff2d882e68a16154564dda4135ad32af9d7d21e75
ncb-sem-b158ae5ae8b91424
psychosis
[ "ncb21-task-da5e99ebb21436f6" ]
[ "ad_aging_q043" ]
aligned_with_safety_augmentation
ncb-scientific-f143dbf87a77594f
scientific
ncb-claim-e9cfe2277ad61e00
{ "claim_id": "ad_aging_q043", "covariates": [ "sex", "site" ], "discovery_cohort": "OASIS3_fMRI_DISC", "estimand": { "direction": "negative", "group": null, "outcome": "fc_fc_Default_Default_z", "predictor": "age", "region_set": null, "type": "association", "unit": "scalar...
f143dbf87a77594f45f0c498342b2f4b17215390bf78679a21770bcc782da655
ready
fMRI-FC
f143dbf87a77594f45f0c498342b2f4b17215390bf78679a21770bcc782da655
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "ad_aging_q043", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "ad_aging" ...
In OASIS3_fMRI_DISC, among participants with diagnosis code 0, is older age associated with lower fc_fc_Default_Default_z, adjusting for sex?
bbf6ce17f877d6799d5fd59d11b01b3529c05a2439aeb61b1c01872259a184b8
ncb-scientific-f143dbf87a77594f
0714393b69960662703541921f203314c4a8b6aaf659a205cda6bb52ebee30fe
ncb-sem-e9cfe2277ad61e00
ad_aging
[ "ncb21-task-bed2c3bc8ea49212" ]
[ "pubmed_35359026_35359026_1" ]
aligned
ncb-scientific-f3636d57e59fc807
scientific
ncb-claim-dcd74e842d675115
{ "claim_id": "pubmed_35359026_35359026_1", "covariates": [ "age", "sex", "site" ], "discovery_cohort": "ABCD_DISC", "estimand": { "direction": "two_sided", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "fc_fc_", "predictor...
f3636d57e59fc80720979dd8e617af6796721000006447ea84631b5fed881c38
ready
fMRI-FC
f3636d57e59fc80720979dd8e617af6796721000006447ea84631b5fed881c38
[ { "prior_label": "candidate_unknown", "source_citation": "PMID:35359026; DOI:10.1002/pchj.544", "source_collection": "stage2_current", "source_id": "pubmed_35359026_35359026_1", "source_mode": "literature_grounded", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_resu...
For literature-grounded ADHD diagnosis versus healthy controls effect on fronto-parietotemporal-striatal functional connectivity in fMRI functional connectivity, using ABCD as discovery and ADHD200 as replication, test the claim with expected direction two_sided and adjust for age;sex;site when available.
d8c0e33c4c876b49b88db412f0cfe834ac58e89011dde47ee2d6ef793c5a9dc5
ncb-scientific-f3636d57e59fc807
4c6ebdb4cbe8aa75e7299a954ff9ab8a2a61fc47665f92cfe82ef22fb294b979
ncb-sem-dcd74e842d675115
adhd
[ "ncb21-task-abfc5beb93a7429a" ]
[ "sex_fc_ukb_hcp" ]
aligned
ncb-scientific-f38be8ab6a8f07ce
scientific
ncb-claim-4a45aa5df3ae914e
{ "claim_id": "sex_fc_ukb_hcp", "covariates": [ "age", "site" ], "discovery_cohort": "UKB_DISC", "estimand": { "direction": "two_sided", "group": { "case": "F", "control": "M", "var": "sex" }, "outcome": "fc_fc_", "predictor": "sex", "region_set": "fc_fc_descr...
f38be8ab6a8f07ce1df876772b2b2987abfe8d7da0a73638f07bf09b7f8218f9
ready
fMRI-FC
f38be8ab6a8f07ce1df876772b2b2987abfe8d7da0a73638f07bf09b7f8218f9
[ { "prior_label": "candidate_unknown", "source_citation": "Ritchie et al. 2018 Cerebral Cortex [VERIFY]", "source_collection": "legacy_scientific", "source_id": "sex_fc_ukb_hcp", "source_mode": "literature", "source_path": "data/claims/fixed_literature_claims.csv", "target_family": "norma...
For sex association with FC descriptors in fMRI-FC, using UKB as discovery and HCP as replication, test the claim with expected direction two_sided and adjust for age;site when available.
7e06971cb92409b74cf0be5e7f4bfe07c0a2679d8b49d129f16516602aa3b07c
ncb-scientific-f38be8ab6a8f07ce
64a71a6d0dd7b1709aeb115b7ec368ccaf81fd496949fb98e14636ca7745b253
ncb-sem-4a45aa5df3ae914e
normative_fmri
[ "ncb21-task-5385bb3754a4a4b3" ]
[ "adhd_q043" ]
aligned_with_safety_augmentation
ncb-scientific-f38d6fdbc4e79d95
scientific
ncb-claim-2b233c027e6c128b
{ "claim_id": "adhd_q043", "covariates": [ "age", "sex", "site" ], "discovery_cohort": "ADHD200_DISC", "estimand": { "direction": "two_sided", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "fc_fc_Cont_Vis_z", "predictor": "...
f38d6fdbc4e79d95965379c89ad839dad19e0303155a580a4d7bcd26ddf9a32d
ready
fMRI-FC
f38d6fdbc4e79d95965379c89ad839dad19e0303155a580a4d7bcd26ddf9a32d
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "adhd_q043", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "adhd" } ]
In ADHD200_DISC and ADHD200_REP separately, is any ADHD diagnosis (dx in {1,2,3}) versus control (dx=0) associated with altered Control-Visual connectivity (fc_fc_Cont_Vis_z), with no additional covariates?
ee68ae43c36d7e8041d4e3c3fc5f38ae133a163b0149de359965b8387562f7ee
ncb-scientific-f38d6fdbc4e79d95
ca8899153ff206ecae725a3354c4d3067f1a0e5ea57dca70ce25121616ede35b
ncb-sem-2b233c027e6c128b
adhd
[ "ncb21-task-55a3ba277e248b31" ]
[ "pubmed_37121277_pmid37121277_vmhc_cluster1_vs_td" ]
ambiguous_unresolved
ncb-scientific-f41a8c5978b01125
scientific
ncb-claim-1671056a239d54c1
{ "claim_id": "pubmed_37121277_pmid37121277_vmhc_cluster1_vs_td", "covariates": [ "age", "sex", "site" ], "discovery_cohort": "ABIDE2_DISC", "estimand": { "direction": "negative", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "...
f41a8c5978b01125b76c9d2800b0f2317936ed7c14759937a1ed14428bc25897
ambiguous_unresolved
fMRI-FC
f41a8c5978b01125b76c9d2800b0f2317936ed7c14759937a1ed14428bc25897
[ { "prior_label": "candidate_unknown", "source_citation": "PMID:37121277; DOI:10.1016/j.bbr.2023.114458", "source_collection": "stage2_current", "source_id": "pubmed_37121277_pmid37121277_vmhc_cluster1_vs_td", "source_mode": "literature_grounded", "source_path": "review-stage/confirm-gates-al...
For literature-grounded ASD Cluster-1 with more severe ADI-R impairment versus typical-development controls effect on remote functional connectivity assessed by voxel-mirrored homotopic connectivity (VMHC) in resting-state fMRI functional connectivity, using ABIDE2 as discovery and ABIDE2 as replication, test the claim...
cda7c9eea9e97b81e3aa87f1bc013cb40799f86999a0d22f76bc36992adc7144
ncb-scientific-f41a8c5978b01125
d7d2436462b52948e35d3ef429406ba65412b74baef81f9bfdfc517ec1043a10
ncb-sem-1671056a239d54c1
asd
[]
[ "asd_q002" ]
aligned_with_safety_augmentation
ncb-scientific-f6cf8c122d61317c
scientific
ncb-claim-0de9c0c5b4d3defc
{ "claim_id": "asd_q002", "covariates": [ "age", "sex", "site" ], "discovery_cohort": "ABIDE1_DISC", "estimand": { "direction": "negative", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "fc_mean_positive", "predictor": "con...
f6cf8c122d61317c21a1377772ef6ad477761ad1859be149fd5cb4bce5a08ef9
ready
fMRI-FC
f6cf8c122d61317c21a1377772ef6ad477761ad1859be149fd5cb4bce5a08ef9
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "asd_q002", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "asd" } ]
In ABIDE1_DISC, with replication assessed in ABIDE1_REP, is fc_mean_positive lower in ASD than HC participants using dx as the predictor and no additional covariates?
50edb8d2e4bed0d10116b990ac5fde158141430a5926aee2298b2c32dd86cb96
ncb-scientific-f6cf8c122d61317c
83301cdd60600664dc5012a018b632daadc8f37a1823fade3a0d66771970ba1c
ncb-sem-0de9c0c5b4d3defc
asd
[ "ncb21-task-6d8377be18725b95" ]
[ "ad_aging_q041" ]
aligned_with_safety_augmentation
ncb-scientific-f7956622f7e3eaf8
scientific
ncb-claim-097fb42632a8bead
{ "claim_id": "ad_aging_q041", "covariates": [ "age", "sex", "site" ], "discovery_cohort": "OASIS3_fMRI_DISC", "estimand": { "direction": "two_sided", "group": { "case": "2", "control": "0", "var": "dx" }, "outcome": "fc_fc_Default_Limbic_z", "predictor": "dx"...
f7956622f7e3eaf82268d3c6d03184df48ef112532d72822e58c2e3b4eb9abd0
ready
fMRI-FC
f7956622f7e3eaf82268d3c6d03184df48ef112532d72822e58c2e3b4eb9abd0
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "ad_aging_q041", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "ad_aging" ...
In OASIS3_fMRI_DISC, with OASIS3_fMRI_REP as a replication cohort, does fc_fc_Default_Limbic_z differ between diagnosis code 2 and diagnosis code 0, adjusting for age and sex?
71fb9709047800171a4ce270a3541de6f23227d9722adf65c0889477236fcd0b
ncb-scientific-f7956622f7e3eaf8
d65b00e51e3114dac528df688675f81550d830b71b489b092d8dcc8c4691d5a0
ncb-sem-097fb42632a8bead
ad_aging
[ "ncb21-task-e15a74e2e1f75001" ]
[ "pubmed_39856610_pmid39856610_1" ]
ambiguous_unresolved
ncb-scientific-f7c3e84a1cb3480d
scientific
ncb-claim-db463aca8239b3e9
{ "claim_id": "pubmed_39856610_pmid39856610_1", "covariates": [ "age", "sex", "site" ], "discovery_cohort": "ABCD_DISC", "estimand": { "direction": "positive", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "fc_fc_", "predic...
f7c3e84a1cb3480df741174bb0e279d66de6682c8fed7217cb12a501ce7abb09
ambiguous_unresolved
fMRI-FC
f7c3e84a1cb3480df741174bb0e279d66de6682c8fed7217cb12a501ce7abb09
[ { "prior_label": "candidate_unknown", "source_citation": "PMID:39856610; DOI:10.1186/s12888-025-06500-4", "source_collection": "stage2_current", "source_id": "pubmed_39856610_pmid39856610_1", "source_mode": "literature_grounded", "source_path": "review-stage/confirm-gates-all-gpt55/combined_...
For literature-grounded ADHD-only group versus healthy controls and ADHD+ODD group effect on Amygdala subregion functional connectivity with left caudate, left putamen, and frontal cortex in resting-state fMRI functional connectivity, using ABCD as discovery and ADHD200 as replication, test the claim with expected dire...
3c967e9ca8ab144689477ad0e34f319232537bd4641b5c15fc9b9aa628dc8e1d
ncb-scientific-f7c3e84a1cb3480d
390e2b34b0b8db4e64e1c0bdf61aa0d98f7bf4a929b186b99cdc45f2c466d45d
ncb-sem-db463aca8239b3e9
adhd
[]
[ "asd_fc_abide2_internal_split" ]
aligned_with_safety_augmentation
ncb-scientific-f849744a3e72c7b0
scientific
ncb-claim-7ccfc692bc2f2980
{ "claim_id": "asd_fc_abide2_internal_split", "covariates": [ "age", "sex", "site" ], "discovery_cohort": "ABIDE2_DISC", "estimand": { "direction": "two_sided", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "fc_fc_", "predi...
f849744a3e72c7b028ed76510b08cfa02e02e994548eb013b88324b322fee36a
ready
fMRI-FC
f849744a3e72c7b028ed76510b08cfa02e02e994548eb013b88324b322fee36a
[ { "prior_label": "fragile", "source_citation": "Haar et al. 2016 [VERIFY]", "source_collection": "legacy_scientific", "source_id": "asd_fc_abide2_internal_split", "source_mode": "inventory", "source_path": "data/claims/fixed_literature_claims.csv", "target_family": "asd" } ]
For ASD case-control FC derivative-table split in fMRI-FC, using ABIDE2 as discovery and ABIDE2 as replication, test the claim with expected direction two_sided and adjust for age;sex when available.
8559379d23c5addc152235d042b44a9cb39d430784401f388980331bfa443435
ncb-scientific-f849744a3e72c7b0
01ccf3bb002b89ba29bfba523bc4ecbee316e7cb56b48ba423f06b9d88d1bfc2
ncb-sem-7ccfc692bc2f2980
asd
[ "ncb21-task-8268cb72ce15ece1" ]
[ "normative_fmri_021" ]
aligned_with_safety_augmentation
ncb-scientific-f84fe6980294c120
scientific
ncb-claim-42378af71a5a3ea8
{ "claim_id": "normative_fmri_021", "covariates": [ "age", "sex", "site" ], "discovery_cohort": "HCP_DISC", "estimand": { "direction": "two_sided", "group": null, "outcome": "fc_fc_Cont_Default_z", "predictor": "phen_fluid_composite", "region_set": null, "type": "associatio...
f84fe6980294c120bccc3de4d0ceb634edd5c41e1166cc53760b2275e4bae482
ready
fMRI-FC
f84fe6980294c120bccc3de4d0ceb634edd5c41e1166cc53760b2275e4bae482
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "normative_fmri_021", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "norma...
In HCP_DISC, with replication in HCP_REP, is higher cognition associated with altered connectivity between default-mode and control networks (fc_fc_Cont_Default_z), adjusting for age and sex?
96aee9e4045df0936dc512090197b1714506d8f70e189d6949dfa3665e906cc9
ncb-scientific-f84fe6980294c120
d3f54a93a9fe0f4de197f479c2784ef3b1da89ac5afb83c2eb70ee9ab7a8016f
ncb-sem-42378af71a5a3ea8
normative_fmri
[ "ncb21-task-29f2629513c4d93d" ]
[ "cognition_fc_hcp_hcpa" ]
aligned
ncb-scientific-f8671ab0121baaa8
scientific
ncb-claim-95e7b3c2dfa3871c
{ "claim_id": "cognition_fc_hcp_hcpa", "covariates": [ "age", "sex", "site" ], "discovery_cohort": "HCP_DISC", "estimand": { "direction": "two_sided", "group": null, "outcome": "fc_fc_", "predictor": "phen_fluid_composite", "region_set": "functional_connectivity_network_pairs",...
f8671ab0121baaa8a5791c0e10045747b694a1ce29f748624f86d9f6afaec0a9
ready
fMRI-FC
f8671ab0121baaa8a5791c0e10045747b694a1ce29f748624f86d9f6afaec0a9
[ { "prior_label": "underpowered_small_positive", "source_citation": "Marek et al. 2022 Nature", "source_collection": "legacy_scientific", "source_id": "cognition_fc_hcp_hcpa", "source_mode": "literature", "source_path": "data/claims/fixed_literature_claims.csv", "target_family": "normativ...
For cognition association with FC descriptors in fMRI-FC, using HCP as discovery and HCP_Aging as replication, test the claim with expected direction two_sided and adjust for age;sex;site when available.
9047b496d924c1c2397801662673cb5f7b1030b6b878998283c7e84f0611f8f0
ncb-scientific-f8671ab0121baaa8
a8d3ed25fa38d19265c7e5a65dad409a2b90997b3b0600ed24802f4e8954bc76
ncb-sem-95e7b3c2dfa3871c
normative_fmri
[ "ncb21-task-025c8e1301361564" ]
[ "normative_fmri_046" ]
ambiguous_unresolved
ncb-scientific-fa6a1c43897de76e
scientific
ncb-claim-b75975463df8369d
{ "claim_id": "normative_fmri_046", "covariates": [ "age", "site" ], "discovery_cohort": "HCP_DISC", "estimand": { "direction": "two_sided", "group": { "case": "F", "control": "M", "var": "sex" }, "outcome": "fc_fc_Limbic_Limbic_z", "predictor": "sex", "region...
fa6a1c43897de76e60daf3159b1f4d138da5c3e379097711d345459c92618fe6
ambiguous_unresolved
fMRI-FC
fa6a1c43897de76e60daf3159b1f4d138da5c3e379097711d345459c92618fe6
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "normative_fmri_046", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "norma...
Across HCP_DISC and UKB_DISC, with replication in HCP_REP and UKB_REP, do females and males differ consistently in limbic within-network connectivity (fc_fc_Limbic_Limbic_z), adjusting for age and cognition within each cohort?
319414901077be52a5f705ad7452c40d360db1bfc69a5605d757faee77fcd736
ncb-scientific-fa6a1c43897de76e
7302324507950f9bff7f6068131378db7a5861e8bf2b8604eff96a54d139def5
ncb-sem-b75975463df8369d
normative_fmri
[]
[ "adhd_q018" ]
aligned_with_safety_augmentation
ncb-scientific-fa88cbf43e33f82f
scientific
ncb-claim-5197f47ccefe760c
{ "claim_id": "adhd_q018", "covariates": [ "age", "sex", "site" ], "discovery_cohort": "ADHD200_DISC", "estimand": { "direction": "two_sided", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "fc_fc_Default_Limbic_z", "predict...
fa88cbf43e33f82fcef46c1858dd805b62032cbff227c248bd865d0b9f056574
ready
fMRI-FC
fa88cbf43e33f82fcef46c1858dd805b62032cbff227c248bd865d0b9f056574
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "adhd_q018", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "adhd" } ]
In ADHD200_DISC, do participants with any ADHD diagnosis (dx in {1,2,3}) show altered Limbic-Default connectivity (fc_fc_Default_Limbic_z) compared with controls (dx=0), with no additional covariates, and is the result directionally consistent in ADHD200_REP?
3e90e662beb1ef3d425a7ae84472ad06809ce7db9af7a4002ad6993cc9853257
ncb-scientific-fa88cbf43e33f82f
8842fa401b2ad25bd7c2028318d7bace4343ab78f0bcb2e4a4e85ee42da0a6a9
ncb-sem-5197f47ccefe760c
adhd
[ "ncb21-task-f2e2f0b7031285ab" ]
[ "normative_fmri_050" ]
ambiguous_unresolved
ncb-scientific-faaaeb165e293001
scientific
ncb-claim-950ac04f921ee414
{ "claim_id": "normative_fmri_050", "covariates": [ "sex", "site" ], "discovery_cohort": "ABCD_DISC", "estimand": { "direction": "two_sided", "group": null, "outcome": "fc_fc_Cont_Default_z", "predictor": "age", "region_set": null, "type": "association", "unit": "scalar" ...
faaaeb165e29300168533c3f46df10bc022f709f42e5ae34a3f8f39f6583b00b
ambiguous_unresolved
fMRI-FC
faaaeb165e29300168533c3f46df10bc022f709f42e5ae34a3f8f39f6583b00b
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "normative_fmri_050", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "norma...
Across ABCD_DISC, HCP_DISC, HCP_Aging_DISC, and UKB_DISC, with corresponding replication cohorts, is higher age associated with cohort-dependent differences in default-mode to control-network connectivity (fc_fc_Cont_Default_z), adjusting for sex and cognition within each cohort and restricting ABCD to dx=0.0?
0c7a9c8fdb396956aa6224ea025fab911af0f46bc4c1977ef9b02349d2e59bb9
ncb-scientific-faaaeb165e293001
c040543d7757cea52bc46bb0a60d9de7dc21541207b38d7e4fbbed86f0679a59
ncb-sem-950ac04f921ee414
normative_fmri
[]
[ "adhd_q047" ]
aligned
ncb-scientific-feb70aa94fa7c90f
scientific
ncb-claim-8735a48780a17800
{ "claim_id": "adhd_q047", "covariates": [], "discovery_cohort": "ABCD_DISC", "estimand": { "direction": "two_sided", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "fc_fc_Default_DorsAttn_z", "predictor": "confirm_dx", "region_set": ...
feb70aa94fa7c90fa2df8c05f733ba5d944a5de106a49eb36eb63cbfa0415e66
ready
fMRI-FC
feb70aa94fa7c90fa2df8c05f733ba5d944a5de106a49eb36eb63cbfa0415e66
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "adhd_q047", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "adhd" } ]
Across ABCD_DISC and ADHD200_DISC, using each cohort's available ADHD-control coding separately (ABCD dx=1.0 vs 0.0 excluding missing dx; ADHD200 dx in {1,2,3} vs 0), is the ADHD association with Default-DorsalAttention connectivity (fc_fc_Default_DorsAttn_z) in the same direction, with no additional covariates?
8b63ca6230fea2f14399ec682f45c8c5b098b159b529849780b7bac031ce5ac8
ncb-scientific-feb70aa94fa7c90f
f5ac6bbdb3a6e7f198712152259b8996498b8a69dd1a301e6fae213e1d03f000
ncb-sem-8735a48780a17800
adhd
[ "ncb21-task-a71d3a3c1b344c50" ]
[ "asd_q010" ]
aligned_with_safety_augmentation
ncb-scientific-ff4d46696cfed68a
scientific
ncb-claim-bcd31e36404b748e
{ "claim_id": "asd_q010", "covariates": [ "age", "sex", "site" ], "discovery_cohort": "ABIDE1_DISC", "estimand": { "direction": "negative", "group": { "case": "case", "control": "control", "var": "confirm_dx" }, "outcome": "fc_mean_abs", "predictor": "confirm_...
ff4d46696cfed68a15180d4899c7d603dd7670c50318e776fa4991d2d5e8a6fe
ready
fMRI-FC
ff4d46696cfed68a15180d4899c7d603dd7670c50318e776fa4991d2d5e8a6fe
[ { "prior_label": "candidate_unknown", "source_citation": "llm_proposed", "source_collection": "stage2_current", "source_id": "asd_q010", "source_mode": "llm_proposed", "source_path": "review-stage/confirm-gates-all-gpt55/combined_benchmark_results.json", "target_family": "asd" } ]
Across ABIDE1_DISC, ABIDE1_REP, and ABIDE1_HOLDOUT, is fc_mean_abs consistently lower in ASD than HC participants using dx as the predictor and no additional covariates?
5bb6a111662d9a6480cf56bdb0538109851d07757d8050b3b0e86642b146273a
ncb-scientific-ff4d46696cfed68a
0c31d1878724b277aab674a0169eaa62f9cd8b8f87554e1aff5b230be216412d
ncb-sem-bcd31e36404b748e
asd
[ "ncb21-task-a5379172f56f4390" ]
[ "neg_underpowered_hcp_s3" ]
aligned_with_safety_augmentation
ncb-synthetic-stress-015db0b6e9d5687e
synthetic_stress
ncb-claim-c987142e6758f177
{ "claim_id": "neg_underpowered_hcp_s3", "covariates": [ "age", "site" ], "discovery_cohort": "neg_underpowered_hcp_s3_DISC", "estimand": { "direction": "two_sided", "group": { "case": "F", "control": "M", "var": "sex" }, "outcome": "fc_fc_Default_SomMot_z", "pred...
015db0b6e9d5687ec19738349420306cc81f28b8433ef780d0d7db2024f1ce1f
ready
fMRI-FC
015db0b6e9d5687ec19738349420306cc81f28b8433ef780d0d7db2024f1ce1f
[ { "prior_label": "fragile", "source_citation": "synthetic_stress", "source_collection": "synthetic_stress_v7", "source_id": "neg_underpowered_hcp_s3", "source_mode": "synthetic_stress", "source_path": "review-stage/claim-search-safety-gpt55-r10-c10-v7/gates/known_negative_results.json", ...
Programmatic synthetic known-null/fragile negative stress claim.
bc9561cf36451f71dc170eed589166cd8b983c6f180f4002d802967d428dd31f
ncb-synthetic-stress-015db0b6e9d5687e
54b36d53665eca136b68db1b5d14d2f9fa6426ff7b3bc7492aa1047013d3f291
ncb-sem-c987142e6758f177
synthetic_stress
[ "ncb21-task-9ce60cabf58259fd" ]
[ "neg_random_label_hcp_aging_s3" ]
aligned_with_safety_augmentation
ncb-synthetic-stress-0558f914b0d8e6af
synthetic_stress
ncb-claim-e5f4736ba285492f
{ "claim_id": "neg_random_label_hcp_aging_s3", "covariates": [ "age", "sex", "site" ], "discovery_cohort": "neg_random_label_hcp_aging_s3_DISC", "estimand": { "direction": "two_sided", "group": { "case": "case", "control": "control", "var": "bench_group" }, "outco...
0558f914b0d8e6af1cc80c25d87ae31dbf6d3c1644b91c484700b940bdebecfa
ready
fMRI-FC
0558f914b0d8e6af1cc80c25d87ae31dbf6d3c1644b91c484700b940bdebecfa
[ { "prior_label": "known_null", "source_citation": "synthetic_stress", "source_collection": "synthetic_stress_v7", "source_id": "neg_random_label_hcp_aging_s3", "source_mode": "synthetic_stress", "source_path": "review-stage/claim-search-safety-gpt55-r10-c10-v7/gates/known_negative_results.js...
Programmatic synthetic known-null/fragile negative stress claim.
bc9561cf36451f71dc170eed589166cd8b983c6f180f4002d802967d428dd31f
ncb-synthetic-stress-0558f914b0d8e6af
f55822497d3d317b6951b21f635480be2a35ccb4ea3df8f688cd8d653644646f
ncb-sem-e5f4736ba285492f
synthetic_stress
[ "ncb21-task-04fa81db8cc4cf61" ]
[ "neg_site_confound_fbirn_s3" ]
aligned_with_safety_augmentation
ncb-synthetic-stress-061d1b244a34b451
synthetic_stress
ncb-claim-8d1222215fedf5fc
{ "claim_id": "neg_site_confound_fbirn_s3", "covariates": [ "age", "sex" ], "discovery_cohort": "neg_site_confound_fbirn_s3_DISC", "estimand": { "direction": "two_sided", "group": { "case": "case", "control": "control", "var": "bench_group" }, "outcome": "fc_between_n...
061d1b244a34b451a4973d4eb1f9f1ca0a9bf851d059f082b66092b2f08bb1a3
ready
fMRI-FC
061d1b244a34b451a4973d4eb1f9f1ca0a9bf851d059f082b66092b2f08bb1a3
[ { "prior_label": "known_null", "source_citation": "synthetic_stress", "source_collection": "synthetic_stress_v7", "source_id": "neg_site_confound_fbirn_s3", "source_mode": "synthetic_stress", "source_path": "review-stage/claim-search-safety-gpt55-r10-c10-v7/gates/known_negative_results.json"...
Programmatic synthetic known-null/fragile negative stress claim.
bc9561cf36451f71dc170eed589166cd8b983c6f180f4002d802967d428dd31f
ncb-synthetic-stress-061d1b244a34b451
7f40a346bcefe0b597b5c0fef2fb543dca673a60ba4be31807aff17aa7312a5c
ncb-sem-8d1222215fedf5fc
synthetic_stress
[ "ncb21-task-7ae540af62da3c12" ]
[ "neg_site_confound_oasis3_s3" ]
aligned_with_safety_augmentation
ncb-synthetic-stress-064719283da9679c
synthetic_stress
ncb-claim-c7a7434678d2c966
{ "claim_id": "neg_site_confound_oasis3_s3", "covariates": [ "age", "sex", "eTIV" ], "discovery_cohort": "neg_site_confound_oasis3_s3_DISC", "estimand": { "direction": "two_sided", "group": { "case": "case", "control": "control", "var": "bench_group" }, "outcome":...
064719283da9679ced5bd065909fa8877cd1b4852ca9b0a39db376c83c19765e
ready
sMRI
064719283da9679ced5bd065909fa8877cd1b4852ca9b0a39db376c83c19765e
[ { "prior_label": "known_null", "source_citation": "synthetic_stress", "source_collection": "synthetic_stress_v7", "source_id": "neg_site_confound_oasis3_s3", "source_mode": "synthetic_stress", "source_path": "review-stage/claim-search-safety-gpt55-r10-c10-v7/gates/known_negative_results.json...
Programmatic synthetic known-null/fragile negative stress claim.
bc9561cf36451f71dc170eed589166cd8b983c6f180f4002d802967d428dd31f
ncb-synthetic-stress-064719283da9679c
d21951525df5a92d120197b54d999082a1a0fe85e4be85f678ca30da66658403
ncb-sem-c7a7434678d2c966
synthetic_stress
[ "ncb21-task-b691ac42ecffb6ff" ]
[ "neg_site_confound_adni_fmri_s3" ]
aligned_with_safety_augmentation
ncb-synthetic-stress-06e49e0c9bfc3666
synthetic_stress
ncb-claim-064d61debc7f3906
{ "claim_id": "neg_site_confound_adni_fmri_s3", "covariates": [ "age", "sex" ], "discovery_cohort": "neg_site_confound_adni_fmri_s3_DISC", "estimand": { "direction": "two_sided", "group": { "case": "case", "control": "control", "var": "bench_group" }, "outcome": "fc_f...
06e49e0c9bfc3666a5358fda403723fd979220c507cf65958e3638421a37f45e
ready
fMRI-FC
06e49e0c9bfc3666a5358fda403723fd979220c507cf65958e3638421a37f45e
[ { "prior_label": "known_null", "source_citation": "synthetic_stress", "source_collection": "synthetic_stress_v7", "source_id": "neg_site_confound_adni_fmri_s3", "source_mode": "synthetic_stress", "source_path": "review-stage/claim-search-safety-gpt55-r10-c10-v7/gates/known_negative_results.j...
Programmatic synthetic known-null/fragile negative stress claim.
bc9561cf36451f71dc170eed589166cd8b983c6f180f4002d802967d428dd31f
ncb-synthetic-stress-06e49e0c9bfc3666
0f3b379b8c32ebfa280be7c513cf0e34357f18fd5257d64afd98681190448b0b
ncb-sem-064d61debc7f3906
synthetic_stress
[ "ncb21-task-3888f34a7ee0dbb2" ]
[ "neg_site_confound_adhd200_s1" ]
aligned_with_safety_augmentation
ncb-synthetic-stress-096741f8365b47ec
synthetic_stress
ncb-claim-d8585cd2fa6529e7
{ "claim_id": "neg_site_confound_adhd200_s1", "covariates": [ "age", "sex" ], "discovery_cohort": "neg_site_confound_adhd200_s1_DISC", "estimand": { "direction": "two_sided", "group": { "case": "case", "control": "control", "var": "bench_group" }, "outcome": "fc_fc_Co...
096741f8365b47ecb19243e6f39369963b57310b3868f7a6695b52afb135005c
ready
fMRI-FC
096741f8365b47ecb19243e6f39369963b57310b3868f7a6695b52afb135005c
[ { "prior_label": "known_null", "source_citation": "synthetic_stress", "source_collection": "synthetic_stress_v7", "source_id": "neg_site_confound_adhd200_s1", "source_mode": "synthetic_stress", "source_path": "review-stage/claim-search-safety-gpt55-r10-c10-v7/gates/known_negative_results.jso...
Programmatic synthetic known-null/fragile negative stress claim.
bc9561cf36451f71dc170eed589166cd8b983c6f180f4002d802967d428dd31f
ncb-synthetic-stress-096741f8365b47ec
20bb58f90bbf73c2c07e0b26f3841c8057b7a1077762c36e08c88b168f6bea87
ncb-sem-d8585cd2fa6529e7
synthetic_stress
[ "ncb21-task-c10905f83a2b5a38" ]