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Estimation of overall mortality ratio (relative risk) was carried out using the random e ects model according to DerSimonian and Laird [9].
method
Methods
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2098391def9f8db6d400497b9ba397d526d227c3
…activation patterns were consistent with the results of the previous studies on infants (Dehaene-Lambertz et al., 2002, 2004) and adults (Petersen et al., 1988; Price, 2000; Homae et al., 2002); all of these studies reported that the both hemispheres are involved in processing of speech sounds.
result
3. Results
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aff0ce725691d9849a86273863de7f448372a33c
The biological processes underlying physiological hypofunction of the salivary glands is not yet well understood, although the involvement of ROS is suspected [1-4].
background
Discussion
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e4398ca801ea20cfc32d174f6ee7b013d2d77ebc
nidulans, we made use of a simple but straightforward approach as it had been described recently (Ray et al., 2004).
method
Results
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526ab4add507b2390400593681209e8a4ddd6b48
In contrast to our results, one study reported that high AI correlated with poor survival of MPM patients [31], but the overall prognostic significance of apoptosis in cancer remains unclear [33, 34].
result
Discussion
db05280740e52e647187f86e46c38f24a7481b88
None
Moreover, these general network properties were demonstrated to have great impacts on the networkbased problems, such as traffic transport [12, 13, 14, 15, 16], epidemic spreading [17, 18, 19, 20, 21], network attacks [22, 23, 24, 25, 26, 27, 28], synchronization [29, 30] and control [31, 32, 33, 34, 35, 36], link pred...
background
1. Introduction
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e1ca362376e6ee706e1f54aefae8fd9374cb8c3b
Oxidative damage of telomeres along with a general damage of DNA because of aged and thereby inefficient mitochondria could be an explanation (Chen et al., 1995), although contradictory results have been published on this matter (von Zglinicki et al., 2000; Britt-Compton et al., 2009).
result
Discussion
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2dcac0993e5e55d2576f6f597761d98b64607474
The STSS is thought to be mediated by the release of SPEs and other antigens, which function as superantigens (Proft et al., 2003; Marrack and Kappler, 1990; Talkington et al., 1993; Baxter and McChesney, 2000; Eriksson et al., 1999; Darenberg et al., 2004; Norrby-Teglund et al., 2005; Zurawski et al., 1998; Ekelund et...
background
4. Discussion
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d610bcbd3f209564b658758dfa2be77a4517d658
The PPR and PRA-based approaches, together with the baseline, have been applied over graphs 1 and 2 (without and with SVO-inferred relationships, respectively).
method
4.4 Experimental settings
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3baecc04e1341cbae7999e8f61a3946c76504828
, 2008), high-order partial differential equations (Bai and Feng, 2007; Moraschi et al., 2010), diffusion tensor Enhancing quality in Diffusion Tensor Imaging with anisotropic anomalous diffusion filter
background
9efebeada238948c156bb066fab1b2bc174f2f29
0230905979a5e3fdb60e74bd505e79ac0746ec56
Moreover, the key regulator of Fe homeostasis, Fur, is also directly regulated by PerR at the transcriptional level (Fuangthong et al., 2002).
background
Discussion
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855f0edac470b58ab2dc7ecb8e873c970f273a23
We generalize the model of Parke (1999), and it appears that fractional orders of integration at the seasonal frequencies may be caused by aggregation of seasonal duration processes.
background
1 Introduction
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91695bee521ee44b2c08a87d9693953afc26583f
…cocaine seeking progressively increases over the first months of withdrawal from extended-access cocaine self-administration and remains elevated even 6 months after the last exposure (Neisewander et al., 2000; Grimm et al., 2001; Lu et al., 2004b; c; Sorge and Stewart, 2005; Pickens et al., 2011).
background
Introduction
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78d26d223331a183fe108eaee8cf1b444e09e1b2
The finding that BMI is closely related to TBF and PBF derived from DXA is compatible with several previous investigations in children over a wide age range and in adults (7, 13, 14, 16, 22, 24, 30, 32, 36).
result
BMI As a Measure of Body Fatness
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The results of the present dead weight noise testing indicate that the ‘CoP path velocity’ noise of the WBB (4.1–5.3 mm s 1) is considerable, which is in accordance with Pagnacco et al. (2011).
result
4. Discussion
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However, our previous data on healthy paediatric patients (age 3 to 18 years) undergoing catheterisation for atrial septal defect closure resulted in a transfer function with the same peak at the fourth harmonic as demonstrated by Nichols and O’Rourke [8] suggesting the validity of this technique [9].
method
Methods
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6aa70abfd2a3982e48006d40da5e05e40c41d330
…the growth of not only Bifidobacteria, but also of strains belonging to the Bacteroidetes and Actinobacteria phyla, while inhibiting Firmicutes strains (especially Clostridium) (Martinez et al., 2010), which is consistent with the presented results on the dietary fiber K1 and K2 preparations.
result
RESULTS AND DISCUSSION
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(Notice that opponent spatiotemporal energy magnitude will be relatively large in response to a locally coherent motion [34].
background
3 Empirical Evaluation
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3e971afd36fbfdd80c34d708865bf1903145fcee
In addition, we recently demonstrated the important role of another 89-kDa periplasmic protein localized in the invasion tip during bacterial escape from the host digestive vacuole, migration through the host cytoplasm towards the target nucleus, and invasion into the macronucleus (Iwatani et al., 2005).
background
Introduction
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6d6bb93872a190de290f259e63587db4f17d539c
Our results regarding cortisol are in line with several studies showing that sleep deprivation elevates cortisol levels.(34)
result
DISCUSSION
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692ac157cba28ba0788d0455082228ca9175837e
Prior findings of a strong correlation between exposure to a pathogenic environment and CRP in the CLHNS sample provided impetus to further examine gene-by-pathogen interactions on CRP level [9, 10].
background
DISCUSSION
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e54474e265b7e84a9254c1b533459a0550af312b
Our proposed algorithm seeks to improve upon the performance of several existing algorithms, including ABS [47, 48, 18, 43], local principal component analysis (PCA) [5], local adaptive singular value cancellation (aSVC) [1] and non-local aSVC [1, Section 3.
method
2. Method
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, 1998) and human (Straiker et al., 1999; Porcella et al. 2000) ciliary bodies of signi®cantly detectable levels of CB1 transcripts and proteins.
background
Discussion
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cd5fd50d44267650aa5a113f044ee333a58c7abb
These findings are in concordance with previously published studies suggesting a negative impact of Af sensitization in CF.15–17 Af sensitization likely facilitates CF-ABPA and multiple factors, including degree of fungal exposure, mucus viscosity, immune status, atopy and age may also have interdependent roles.1...
result
DISCUSSION
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a867147facea7cf7d2c288b89bf90b2b5d0ccc00
In this sense, accidentally encountered information is also always algorithmically framed and often personalised by for example previous searches and geographical location (e.g. Abel et al., 2011; Feuz et al., 2011; Hannak et al., 2013).
method
Literature review
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The involvement of the clock in Pai-1 gene regulation has been described (Maemura et al., 2000; Minami et al., 2002; Schoenhard et al., 2003; Oishi et al., 2005a; Chong et al., 2006; Oishi et al., 2007), although the precise molecular mechanism on how the clock regulates the intrinsic daily…
background
1. Introduction
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In contrast to most plant PPR proteins identified so far, which contain 12 PPR repeats on average (Lurin et al., 2004; Tourasse et al., 2013), PPR7 consists of only four PPR units, followed by a very short, positively charged conserved tail (Supplemental Figure 1).
background
RESULTS
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78a4e9cdca8e3bdd90bcca3bacefc86828001e8d
Second, we have previously shown that STAT3 expression was not changed by modulating RKIP expression in 293T cells [60] and third, because 293T cells have a higher transfection efficiency with the plasmids we were using, especially under the serum free conditions used in the experiments described below.
background
Results
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cfa53cc1ff9084a46df8b9d276da90b3521f929a
Several authors (Anderson et al., 2009; Malmierca et al., 2009; Ulanovsky et al., 2004, 2003) use the normalized frequency difference: f norm, f2 − f1√ f1 f2 (A.1) where f1 and f2 have Hertz units, while others use the octave frequency separation (e.g., Von der Behrens et al., 2009).
background
Appendix
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ab521feed89a9397e278fe1cb66cb7f19e3e2704
These polyphenols and other components have been described as having antioxidant (5), pro-oxidant (6), tumor inhibitory (7,8), antiapoptotic (9), antiangiogenesis (10,11), antiestrogenic (12,13), epigenetic (14), and other potentially chemopreventive properties (1,3,4,15,16).
background
Introduction
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518cc15d22ebce4589936bda4685bdeafb02b5c6
The methods of research are described in most detail in [1]; the methods of measurement and analysis of EEG coherence are described in [2]; brief information about their most essential elements is given below.
method
METHODS
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In this study, we restrict perturbations of the kinematic environment to rotations of the visual feedback of the position of the end-effector, since this kind of transformation is well studied in both healthy human subjects and those with neurological disorders (Pine et al. 1996; Contreras-Vidal and Buch 2003).
method
2 Methods
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quantification of RAM in the biological fluids including liquid chromatography-tandem mass spectrometry (LC-MS/MS) (Gupta et al., 2011; Pilli et al., 2011; Patel et al., 2014), high performance
method
INTRODUCTION
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104773ef83b4af176d9eb918ec59c6d977e0d99b
Moreover, two distinct types of regulated secretion have been distinguished in neuronal and neuroendocrine cells (Kelly, 1993).
background
INTRODUCTION
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4b5d4c5c9fdc0197f3e18881938a758cac6fe310
Despite significant variation in the prevalence of unhealthy weights, results of this study are comparable to previous studies [14,16,49] showing the existence of the double burden of malnutrition in the seven African countries.
result
Discussion
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In addition, more than three quarters of 97% OTUs in these proteobacterial classes contain SSU rRNA genes detected in PCR-based studies and appear in the SILVA database [12].
background
Main text
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These spatial variations in the sedimentary regime will drive coral species distributions depending on coral tolerances to sediments [16,17].
background
Discussion
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64a88057d4da320ba2a22ad292982e02081d92ee
zeamais, which could be an attractive alternative considering the great potential of the oil as insecticide and repellent, particularly because it is rich in monoterpenes [18].
background
2. Results and Discussion
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416452593871de7d0ebbd77cf66c9cf94e2da6f7
Binding of C2 domains (C2A, C2B, and C2AB) of SYT2 to phospholipids was measured according to previous descriptions (Fernandez et al., 2001; Fernandez-Chacon et al., 2002; Shin et al., 2003; Schapire et al., 2008).
method
METHODS
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A discussion of particular channel estimation techniques is beyond the scope of this paper, therefore without loss of generality, we use the least-square (LS) channel estimator [14] in Sections IV and V due its widespread adoption in OFDM systems and low computational complexity.
method
II. SYSTEM MODEL
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In addition, according to [6], instead of performing gradient descent based on Wh, we can compute the following formulation as:
background
2 Method
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All katanin derivatives were PCR amplified from the human p60 (McNally and Thomas, 1998) or human p80 (Hartman et al., 1998) cDNAs previously described. p80 derivatives The WD40 domain of p80 (WD) consisted of amino acids 1-304, WDpro consisted of residues 1-484, pro-con80 consisted of residues…
method
Plasmid constructions
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The effect of VEGF on glutamatergic transmission is still controversial, with evidence for both inhibition (McCloskey et al., 2005) and enhancement (Kim et al., 2008).
background
Discussion
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4e3a5a53715d20f587da65ed44a57a7b0ef78ca2
Heavy metals contamination of Bohai Bay in the past few years have been investigated (Zhang et al. 2002; Hua et al. 2005; Wang et al. 2005; Wang and Li 2006; Wang and Wang 2007; Liu et al. 2007; Meng et al. 2008), however, no comparison was available to show the spatial and temporal distribution of heavy metals in the ...
background
f0d0137f72b6964c019ccf4b8ff4b8f002bc35b4
8b7f13e28a23afc9208097b9beefc793bad9a636
First, we prove that deciding whether a set of vertices of a graph G is a clique-transversal is Co-NP-Complete, a problem whose complexity is mentioned as open in [11].
background
1. Introduction
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0049b630e0bf4b14e76e36615c33aed0c39c3dd9
Evidence in the literature suggests that a non-CB1 receptor exists on excitatory terminals in the hippocampus (Hajos and Freund, 2002; Rouach and Nicoll, 2003), but this remains controversial (Hoffman et al., 2005; Kawamura et al., 2006; Takahashi and Castillo, 2006).
background
Introduction
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b13b1cbd30124f18adf4d8c5099313ef218c140c
This is troubling because hyperinsulinemia, a hallmark of insulin resistance, is considered a likely biological mechanism of increased risk for colon cancer and adenoma [1, 21].
background
fbfe2f43a8cc743b21e4177e5d0440849db1724e
412434187174932788fc14d7d51f88ff45b3c0d8
These measures provide important, but indirect, data on personal income, and may suffer from the “ecologic fallacy” of misclassifying income level on the basis of geographic economic factors, which can lead to substantial measurement error (22,23).
background
DISCUSSION
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Alternative splicing of exon 10 produces 2 tau protein isoforms, 3R (without exon 10) and 4R (with exon 10), and a healthy brain includes similar levels of 3R and 4R.(6) One study reported that the MAPT gene region that includes the 30-end of exon 10 and 50end of intron 10–11 is self-complementary and forms a hairpin (...
background
ca51830d6e03d155747f596db8a6486a842794f0
12ef1e4f950bcb45ba6908585b7b9a40a11df93a
4 tend to reach a ‘‘plateau’’ and do not converge at the same point, even though no spontaneous reactivation is detected (Estévez and Vilanova 2009).
background
Discussion
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The increased ODC1 expression after fadrozole treatment may indicate an enhancement of the ODC/polyamine system and/or suggests a new pathway for E2 to regulate GABA production in addition to the known effects of E2 on glutamic acid decarboxylase in goldfish (46).
method
DISCUSSION
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1e1f26aee409b2a156936534cc875861dc5ddcfe
Given their relatively low species diversity, biofilms growing within acid mine drainage (AMD) environments are a model system for the study of ecological processes in natural environments using ‘omic’ techniques (Denef et al., 2010a).
background
Introduction
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The fact that others have shown that continued experience or exposure can modify when perceptual narrowing (or perceptual attenuation) occurs (Pascalis et al., 2005; Scott & Monesson, 2009), and the current results that perceptual discrimination is possible after narrowing has occurred, demonstrate…
background
General Discussion
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This result might explain why high IFP is associated with poor prognosis in human cancer (4, 21, 22).
background
Results and Discussion
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Climatic data Large scale climatic conditions have been shown to affect avian productivity in general (Nott et al. 2002).
background
Methods
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…construction site visit, site trainings, computer games and simulations, and problem-based learning, Though roleplaying is not a popular pedagogical approach adopted in construction education, it has major benefits and potentials for improving students‟ learning (Bhattacharjee & Ghosh, 2013).
background
Introduction
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To get a rough approximation of the divergence time for the main phylogroups, we used both the higher and the lower sequence divergence rates proposed by Pinho et al. (2007) for the ND4–tRNALeu mitochondrial fragment (2.78% and 1.74% per million years, respectively).
method
2.5. Divergence time estimates
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This is in agreement with a previous finding that wt CLN5 is stable in cells [12].
result
Results
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Additionally, MeCP2 has been implicated not in inhibition but in the promotion of activity of some genes(Chahrour et al. 2008).
method
Oligodendrocyte development
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Differences between the immune function of males and females have also been reported for birds (Romano et al., 2011), reptiles (Svensson et al., 2009) and fish (Hoeger et al., 2005).
background
2.4.4. The microbiome in relation to stress and immunity
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There is strong evidence that accumulation of Aβ peptide is responsible for age-related memory decline in these mice [5–7].
background
1. Introduction
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DCS is preferable to External Storage (ES) at the base station, especially when there are many types of event to detect and report, and not all event types are queried often in a large network [56].
background
4.1 Introduction
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6A) do not follow the characteristic dipper function found for superimposed masking (Legge and Foley, 1980; Foley, 1994).
background
Discussion
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Given that normal hippocampal functioning is essential for both episodic AM and everyday memory (Vargha-Khadem et al., 1997; Isaacs et al., 2000), we also examined the effects of age and sex on everyday memory in order to determine whether the results would be similar to those observed in episodic…
result
DISCUSSION
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These results are aligned with the claims made by authors such as Kampenes et al. (2009), Jackson (2002), GroÃànniger et al. (2007), Petre (1995), as it was discussed in Sect.
result
5 Discussion
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…as: P xið Þ ¼ e aþ Pn j¼1 bjxij 1þ e aþ Pn j¼1 bjxij : ð1Þ Here P(xi) is the probability of detection (0–1) of MODIS pixel i based on the linear combination of ASTER fire pixel summary statistics ( j=1,n), and α and βj are parameters derived from the data (Agresti, 1990; Morisette et al., 2005b).
method
3. Methods
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Nitrogen levels in the medium also influence the transcription of the ech42 endochitinase gene (Donzelli and Harman 2001).
background
Discussion
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The electrode locations, acquired with a post-implantation CT were projected on the T1weighted individual anatomy scan (Hermes et al. 2010).
method
Methods
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3 To this end, the proposed method is compared with several recommendation methods including User-based CF (UCF), Item-based CF (ICF) [51], SlopeOne [52], SVD++ [53], TARS [12], SoRec [31], SoReg [54], TrustMF [22], SocialMF [28], TrustSVD [25], IPG [26], CETrust [21], and 2DGC [55].
method
4 Experiments
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Protocol The study protocol followed the recommendations of the PRISMA statement and Cochrane Collaboration for systematic reviews and meta-analysis [12,13].
method
Methods
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Harpins are found to mediate HRbased PCD and produce elevated defense responses in plants (Lee et al. 2001a; Dong et al. 1999).
background
Discussion
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03deebf175f34a88c200a0ef39d0aca8e4ade8e2
The sequence of intermediates in the hR photocycle and their interconversions have been the subject of numerous studies (Va´ró et al., 1995a, b; Hazemoto et al., 1984; Zimányi and Lanyi, 1989a, b; Zima´nyi et al., 1989; Spencer and Dewey, 1990; Ames et al., 1992; Dioumaev and Braiman, 1997a).
background
INTRODUCTION
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…and high levels of defecation are interpreted as indicators of high levels of emotionality (DeFries, Wilson, & McClearn, 1970; Flint et al., 1995; Gervais, 1976), although the validity of ambulation and defecation as indexes of emotionality has been questioned (Lister, 1990; Ramos & Mormède, 1998).
background
1.2 Emotionality
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Following prior work (Haghighi et al., 2008; Prochasson and Fung, 2011; Vulić and Moens, 2013b), we retain only nouns that occur at least 5 times in the corpus.
method
3 Experimental Setup
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5 nM and individuals need to ingest at least 25–50 μg of vitamin D per day to sustain a blood level of > 75 nM 25(OH) vitamin D [22, 23].
background
Introduction
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The Caribbean sample includes sequences from Panama that were previously obtained by McCartney and Lessios (2004), with GenBank accession numbers AY451242–AY451275.
background
Materials and Methods
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The LAA orifice area was then calculated by using the equation [19]: LAA orifice area = π x (Dmax/2) x (Dmin/2).
method
Methods
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Discussion In the past five years, several studies have aimed to evaluate the impact of PTGS2 SNPs on the risk of developing different types of cancer [10,15,16,21-46].
background
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Fluoroscopy-guided anterior scalene (ASM) or pectoalis minor (PM) muscle blocks, or both, with local aneshetic were frequently used to help reinforce the clinical iagnosis of NTOS and to provide additional insight into he likely responsiveness to treatment.(7,11) All patients not reviously treated for NTOS and those fo...
method
METHODS
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It is estimated that the abuse and misuse of prescription opioids are responsible for somewhere between $53 to $72 billion in cumulative costs annually.(33,34) These fig-
background
Morbidity and Economic Burden
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that can destroy tumor cells but are instead induced to suppress anti-tumor immune responses by releasing elevated levels of the immune suppressive products, nitric oxide, IL10 and TGF- , and down-regulating levels of the immune stimulatory product IL-12 [10, 17, 14, 20].
background
Introduction
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…either undergoing pain or suffering emotionally, localized a core network including anterior insula (AI), inferior frontal gyrus (IFG), and anterior midcingulate cortex (aMCC) (Singer et al. 2004; Jackson et al. 2006; Singer 2006; Decety and Moriguchi 2007; Fan et al. 2011; Lamm et al. 2011).
background
Introduction
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The differential magnitude of effect in large versus small studies (Ioannidis et al. 2003; Zintzaras et al. 2005) for the allele contrast was tested using the Egger regression test for funnel plot asymmetry (Egger et al. 1997) and the Begg-Mazumdar test, which is based on Kendall’s tau (Begg and…
method
Methods
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Even, the GU toxicity in our study are high, the observed rate averaged those described in former reports [1,4,5,7,10,11,25].
result
Discussion
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…of these findings, the difference in thigmotaxis between the selectively bred HOFT and LOFT mice seemed to be a stable and robust feature of these animals, suggesting that the two lines differed with regard to trait anxiety rather than to state anxiety (see Belzung & Griebel, 2001; Lister, 1990).
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5.2 Stability of the selection trait
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Division of Arabidopsis thaliana Proteins into Families using PFAM Each probeset in the Affymetrix ATH1 microarray platform was mapped using BLAST (Altschul et al., 1990) to the Table 3.
method
METHODS
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The computational system arising from the ad-hoc computation network point of view has been modeled by combining the notion of distributed data streams [5] with classic distributed approaches to solve problems on particular topologies [6] as the SSSF model [2].
method
1 Introduction
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Matthews et al. (2002) concluded that 3–4 days monitoring were required to correctly measure moderate-to-vigorous physical activity (MVPA), and that 7 days were needed to reliably estimate physical inactivity [5].
background
Background
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Force feedback (FFB) has been shown to increase the usability and to decrease the cognitive workload during the surgery, as reflected in faster learning curves (Narazaki et al. 2006; Okamura 2009).
background
Introduction
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Trait data collection We used 10 plant functional traits related to growth, survival, and the response to environmental change (Pérez-Harguindeguy et al. 2013), including leaf area (LA; mm2), specific leaf area (SLA; mm2 g 1), chlorophyll content (measured by the SPAD device unit [see below]),…
method
Methods
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Infection Control Measures/Investigation of Implicated Re-useable Medical Device: After the first site visit on May 31, 2006, ACDC issued interim recommendations including adding antibiotic coverage from gram-negative organisms for cardiac surgery patients, collecting surveillance cultures (sputum) on all intubated CVI...
method
METHODS
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Bifidobacteria is the third most common genus in the human intestine, constituting about 3% of the adult fecal flora and more than 75% of the infant fecal flora (Langendijk et al., 1995; Franks et al., 1998; Harmsen et al., 2000).
background
Results and discussion
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Exercise has an important role not only in promoting general health but also in the prevention and treatment of various kinds of ailments, such as mood disorders (Agras, 1995) and constitutional hypotension (Duschek and Schandry, 2007).
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1. Introduction
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Note that Drieghe et al. (2008) have proposed that parafoveal-on-foveal effects (i.e., an effect of the word to the right of fixation that appears in the eye movement record before the eyes have actually left the fixated word) may be likely to arise in cases in which the saccadic targeting system…
background
Discussion
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Starting from the reference C-based implementation provided in the CORTEXSUITE, a recently-released suite of benchmarks designed to challenge current hardware systems [26], we completed a design specification in synthesizable SystemC that is parametric with respect to the PLM size.
method
4. EXPERIMENTAL SETUP
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The level of expression of amyloid- protein precursor investigated gene did not coincide with the earlier data concerning staining of different parts of amyloidprotein precursor in the rat cortex [17, 21].
result
DISCUSSION
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This transition was introduced first by Prince and Elder (2007) and it simplifies formulas for parameter update on Mstep of EM algorithm.
method
Appendix A. learning G-PLDA mixture model
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Experimental evidence and clinical observations support the concept that these molecules participate in the pathogenesis of organ injury and that their blood levels correlate with severity of illness and outcome (5, 6).
background
Is there a biological rationale for EBT in SIRS/Sepsis?
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The frame rate was set between 60 and 90 frames per second.(7) Echocardiograms were digitally stored and later analysed off-line using acoustic-tracking software (Echo-Pac version 7.
method
Methods
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…side-effects are found with currently available hypnotics, it will be of interest to determine whether newer genetic methods for enhancing sleep in rodents can reverse/attenuate or slow-down Alzheimer's pathology in rodent models (Jego et al., 2013; Konadhode et al., 2013; Anaclet et al., 2014).
background
4. Discussion
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