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"task_id": "MED3",
"title": "Two-hit retinoblastoma, mosaic selection, and sequencing-biased genetic risk",
"category": "Cancer genetics and Bayesian risk modeling",
"instruction_file": "instruction.md",
"input_data": "All parameters and equations needed for the task are embedded in instruction.md.",
"action_schema": {
"type": "object",
"properties": {
"next_sibling_recurrence_risk_given_bilateral_blood_neg": {
"type": "number"
},
"offspring_retinoblastoma_risk_given_unilateral_blood_neg": {
"type": "number"
},
"posterior_constitutional_given_unilateral_blood_neg": {
"type": "number"
},
"posterior_embryonic_mosaic_given_bilateral_blood_neg": {
"type": "number"
},
"posterior_embryonic_mosaic_given_unifocal_unilateral_blood_neg": {
"type": "number"
},
"posterior_embryonic_mosaic_given_unilateral_blood_neg": {
"type": "number"
},
"posterior_parental_gonadal_mosaic_given_unilateral_blood_neg": {
"type": "number"
},
"problem_id": {
"type": "string",
"const": "MED3"
},
"sporadic_expected_foci_per_million_wildtype": {
"type": "number"
}
},
"required": [
"next_sibling_recurrence_risk_given_bilateral_blood_neg",
"offspring_retinoblastoma_risk_given_unilateral_blood_neg",
"posterior_constitutional_given_unilateral_blood_neg",
"posterior_embryonic_mosaic_given_bilateral_blood_neg",
"posterior_embryonic_mosaic_given_unifocal_unilateral_blood_neg",
"posterior_embryonic_mosaic_given_unilateral_blood_neg",
"posterior_parental_gonadal_mosaic_given_unilateral_blood_neg",
"problem_id",
"sporadic_expected_foci_per_million_wildtype"
],
"additionalProperties": true,
"description": "All numerical values must be finite JSON numbers. Exact per-field domains, units and tolerances are specified by the instruction and verifier."
},
"external_data_required": false
}
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