accession
stringlengths
6
10
name
stringlengths
6
11
Full Name
stringlengths
1
147
⌀
taxon
stringlengths
3
46
⌀
sequence
stringlengths
48
2.3k
function
stringlengths
11
1.34k
AlphaFoldDB
stringlengths
6
10
Q7NVY4
LPXD_CHRVO
UDP-3-O-acylglucosamine N-acyltransferase
Chromobacterium
<M><S><Y><T><L><E><H><I><V><K><Q><L><G><G><A><L><R><G><P><N><R><E><V><S><R><L><A><P><L><E><L><A><G><A><G><E><I><A><F><V><A><S><A><K><F><R><R><Q><M><L><E><S><A><A><D><A><L><I><V><T><E><A><L><A><A><E><L><P><D><R><S><L><I><V><A><A><D><P><Y><L><Y><F><A><R><L><A><T><L><F><H><P><P><K><A><P><R><A><G><I><H><P><R><A><V><V><G><V...
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.<BOP>
Q7NVY4
A0M579
RL15_GRAFK
50S ribosomal protein L15
Gramella
<M><D><L><S><N><L><K><P><A><E><G><S><V><R><K><N><S><K><R><I><G><R><G><E><G><S><G><K><G><G><T><A><T><R><G><H><K><G><A><K><S><R><S><G><Y><S><K><K><I><G><F><E><G><G><Q><M><P><L><Q><R><R><V><P><K><F><G><F><T><N><R><N><R><K><V><Y><Q><G><I><N><L><D><T><L><Q><N><L><V><D><E><G><R><I><K><D><T><V><D><M><D><V><L><V><E><N><G><L><A...
Binds to the 23S rRNA.<BOP>
A0M579
Q8QGH2
SUMO1_CHICK
Small ubiquitin-related modifier 1
Gallus
<M><S><D><Q><E><A><K><P><S><A><E><D><L><G><D><K><K><E><G><E><Y><I><K><L><K><V><I><G><Q><D><S><S><E><I><H><F><K><V><K><M><T><T><H><L><K><K><L><K><E><S><Y><C><Q><R><Q><G><V><P><M><N><S><L><R><F><L><F><E><G><Q><R><I><T><D><N><H><T><P><K><E><L><G><M><E><E><E><D><V><I><E><V><Y><Q><E><Q><T><G><G><H><S><T><V>
Ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I. This post-translational modification on lysine residues of pr...
Q8QGH2
O75971
SNPC5_HUMAN
snRNA-activating protein complex 19 kDa subunit
Homo
<M><L><S><R><L><Q><E><L><R><K><E><E><E><T><L><L><R><L><K><A><A><L><H><D><Q><L><N><R><L><K><V><E><E><L><A><L><Q><S><M><I><S><S><R><R><G><D><E><M><L><S><S><H><T><V><P><E><Q><S><H><D><M><L><V><H><V><D><N><E><A><S><I><N><Q><T><T><L><E><L><S><T><K><S><H><V><T><E><E><E><E><E><E><E><E><E><E><S><D><S>
Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.<BOP>
O75971
P0AFQ3
YBHS_ECOL6
Probable multidrug ABC transporter permease YbhS
Escherichia
<M><S><N><P><I><L><S><W><R><R><V><R><A><L><C><V><K><E><T><R><Q><I><V><R><D><P><S><S><W><L><I><A><V><V><I><P><L><L><L><L><F><I><F><G><Y><G><I><N><L><D><S><S><K><L><R><V><G><I><L><L><E><Q><R><S><E><A><A><L><D><F><T><H><T><M><T><G><S><P><Y><I><D><A><T><I><S><D><N><R><Q><E><L><I><A><K><M><Q><A><G><K><I><R><G><L><V><V><I><P...
Part of the ABC transporter complex YbhFSR that could be involved in efflux of cefoperazone. Probably involved in the translocation of the substrate across the membrane.<BOP>
P0AFQ3
Q8UDF5
NORM_AGRFC
Multidrug-efflux transporter
Agrobacterium tumefaciens complex
<M><S><S><S><V><V><A><E><T><V><P><S><G><S><G><S><W><F><S><H><F><K><A><T><L><V><L><G><I><P><L><I><G><A><Q><L><A><Q><L><G><I><H><T><T><D><M><V><I><V><G><Q><L><G><A><E><K><L><A><A><M><V><L><A><G><Q><F><F><F><V><V><F><I><F><G><S><G><F><S><V><A><V><V><P><M><V><A><Q><A><Y><G><Q><G><D><A><T><S><A><R><R><S><L><R><M><G><M><W><V...
Multidrug efflux pump.<BOP>
Q8UDF5
Q9CYH6
RRS1_MOUSE
Ribosome biogenesis regulatory protein homolog
Mus
<M><E><G><Q><R><V><E><E><L><L><A><K><A><E><Q><E><E><A><E><K><L><Q><R><I><T><V><H><K><E><L><E><L><E><F><D><L><G><N><L><L><A><S><D><R><N><P><P><T><V><L><R><Q><A><G><P><S><P><E><A><E><L><R><A><L><A><R><D><N><T><Q><L><L><I><N><Q><L><W><R><L><P><T><E><R><V><E><E><A><V><V><A><R><L><P><E><P><A><T><R><L><P><R><E><K><P><L><P><R...
Involved in ribosomal large subunit assembly. May regulate the localization of the 5S RNP/5S ribonucleoprotein particle to the nucleolus.<BOP>
Q9CYH6
B5Z9A1
EX7S_HELPG
Exodeoxyribonuclease VII small subunit
Helicobacter
<M><Q><D><E><L><F><E><T><E><K><I><P><P><K><N><T><K><N><A><K><N><A><P><K><K><S><F><E><E><H><V><H><S><L><E><Q><A><I><D><R><L><N><D><P><N><L><S><L><K><D><G><M><D><L><Y><K><T><A><M><Q><E><L><F><L><A><Q><K><L><L><E><N><A><Y><L><E><H><E><K><L><Q><T><P><D><K><K><A>
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.<BOP>
B5Z9A1
P37817
SPOVM_BACSU
Stage V sporulation protein M
Bacillus
<M><K><F><Y><T><I><K><L><P><K><F><L><G><G><I><V><R><A><M><L><G><S><F><R><K><D>
Coordinates cortex and coat assembly during sporulation . Associates with the spore coat protein SpoIVA and with the outer forespore membrane, thereby serving as a membrane anchor that tethers SpoIVA and the entire spore coat to the forespore surface . May also serve as a competitive inhibitor of FtsH activity during s...
P37817
Q4A6V0
SYE_MYCS5
Glutamyl-tRNA synthetase
Mycoplasmopsis
<M><N><K><I><R><T><R><Y><A><P><S><P><T><G><F><L><H><I><G><G><A><R><T><A><L><F><C><Y><L><F><A><K><H><F><N><G><D><F><I><F><R><L><E><D><T><D><V><K><R><N><V><E><G><G><E><A><S><Q><L><E><N><L><A><W><L><G><I><I><P><D><E><S><P><L><K><P><N><L><K><Y><G><K><Y><R><Q><S><E><K><L><D><R><Y><K><E><V><L><D><M><L><L><E><K><N><L><A><Y><K...
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).<BOP>
Q4A6V0
Q2LR39
RSMH_SYNAS
rRNA (cytosine-N(4)-)-methyltransferase RsmH
Syntrophus
<M><P><E><G><K><Y><S><Y><H><E><P><V><L><L><E><E><A><I><A><S><L><N><C><R><G><G><G><I><Y><V><D><G><T><V><G><G><G><G><H><A><A><L><I><L><E><R><S><A><P><D><G><F><L><L><G><M><D><V><D><G><D><A><L><Q><A><A><E><K><R><L><M><P><F><G><R><R><K><T><L><V><K><A><N><Y><A><D><M><R><K><V><L><A><D><L><K><I><L><Q><V><D><G><I><L><L><D><L><G...
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.<BOP>
Q2LR39
P82297
HCY2_HOMAM
Hemocyanin subunit 2
Homarus
<G><A><D><V><A><H><K><Q><Q><S><V><N><H><L><L><Y><L><V><T><S><H><Y><P><S><L><D><Y><S><L><L>
Hemocyanins are copper-containing oxygen carriers occurring freely dissolved in the hemolymph of many mollusks and arthropods.<BOP>
P82297
Q1GAN9
METN_LACDA
Methionine import ATP-binding protein MetN
Lactobacillus
<M><S><I><V><Q><L><D><H><V><S><V><T><F><K><R><K><K><A><A><D><V><Q><A><V><Q><D><V><T><L><H><I><E><K><G><D><I><Y><G><I><V><G><F><S><G><A><G><K><S><T><L><V><R><T><I><N><L><L><Q><K><P><T><A><G><D><V><V><V><G><G><V><D><F><V><K><D><G><K><Q><V><I><S><G><K><D><L><Q><A><R><R><R><K><I><G><M><I><F><Q><Q><F><N><L><L><N><E><T><T><V...
Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.<BOP>
Q1GAN9
A4JF06
TIG_BURVG
PPIase
Burkholderia cepacia complex
<M><A><N><V><V><E><N><L><G><K><L><E><R><R><V><T><I><S><L><P><K><D><T><V><Q><K><E><I><D><A><R><I><Q><K><L><A><K><N><V><R><M><P><G><F><R><P><G><K><V><P><L><K><M><V><A><Q><Q><Y><A><G><Q><V><E><A><E><V><L><S><D><K><I><G><Q><E><F><F><T><I><S><R><A><E><N><L><R><V><A><G><Q><P><S><F><E><P><K><Q><E><Q><A><E><D><A><Y><A><F><D><A...
Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.<BOP>
A4JF06
B5XV36
TRUD_KLEP3
tRNA-uridine isomerase D
Klebsiella
<M><I><A><F><D><Q><L><T><W><L><H><G><K><P><Q><S><S><G><L><L><K><A><N><P><E><D><F><L><V><V><E><D><L><G><F><A><P><D><G><E><G><E><H><V><L><V><R><I><L><K><N><G><C><N><T><R><F><V><A><D><A><L><A><K><F><L><K><I><H><A><R><E><V><S><F><A><G><Q><K><D><K><H><A><V><T><E><Q><W><L><C><A><R><V><P><G><K><E><M><P><D><L><S><K><F><Q><L><E...
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.<BOP>
B5XV36
A9QC74
NU3C_TRACE
NADH-plastoquinone oxidoreductase subunit 3
Trachelium
<M><L><L><L><Y><E><Y><D><I><F><W><A><F><L><I><I><S><S><L><I><P><I><L><A><F><F><L><S><G><V><L><A><P><I><S><K><G><P><E><K><F><S><S><Y><E><S><G><I><E><P><I><G><D><A><W><L><Q><F><R><I><R><Y><Y><M><F><A><L><V><F><V><V><F><D><V><E><T><V><F><L><Y><P><W><S><M><S><F><D><V><L><G><V><S><V><F><I><E><A><F><I><F><V><L><I><L><I><V><G...
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translo...
A9QC74
C4Z552
HEM3_LACE2
Pre-uroporphyrinogen synthase
Lachnospira
<M><H><Y><R><I><G><T><R><G><S><K><L><A><L><V><Q><S><E><Y><V><K><R><R><M><E><E><A><Y><P><E><D><T><F><E><L><V><I><I><K><T><T><G><D><K><V><T><D><K><P><L><A><A><I><G><T><K><G><F><F><V><K><E><I><E><E><A><L><L><S><G><S><I><D><M><A><V><H><S><M><K><D><M><P><A><E><C><A><A><G><L><T><F><A><K><A><W><K><R><E><D><C><R><D><V><L><I><L...
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.<BOP>
C4Z552
D8MUB2
SBMC_ERWBE
DNA gyrase inhibitor
Erwinia
<M><N><V><E><I><V><E><R><E><E><S><K><T><A><G><F><H><L><V><G><P><W><E><V><T><A><P><E><G><F><D><K><L><V><A><W><T><S><K><H><N><V><M><G><P><W><M><G><V><Y><H><G><N><P><R><A><V><P><A><E><E><L><K><I><E><T><V><I><G><V><P><T><D><F><E><L><P><E><G><S><E><G><A><R><L><S><I><I><P><A><G><T><Y><A><M><N><L><V><H><V><N><D><G><D><F><T><K...
Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the ce...
D8MUB2
B1LPR3
PHNN_ECOSM
Ribose 1,5-bisphosphokinase
Escherichia
<M><T><G><K><L><I><W><L><M><G><A><S><G><S><G><K><D><S><L><L><T><E><L><R><Q><R><E><Q><T><Q><L><L><V><A><H><R><Y><I><T><R><A><A><S><A><G><S><E><N><H><I><A><L><S><E><Q><E><F><F><T><R><A><G><Q><N><L><L><A><L><S><W><H><A><N><G><L><Y><Y><G><V><G><V><E><I><D><L><W><L><H><A><G><F><D><V><V><V><N><G><S><R><A><H><L><P><Q><A><R><A...
Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).<BOP>
B1LPR3
Q9XHV0
MYB80_ARATH
Protein MALE STERILE 188
Arabidopsis
<M><G><R><I><P><C><C><E><K><E><N><V><K><R><G><Q><W><T><P><E><E><D><N><K><L><A><S><Y><I><A><Q><H><G><T><R><N><W><R><L><I><P><K><N><A><G><L><Q><R><C><G><K><S><C><R><L><R><W><T><N><Y><L><R><P><D><L><K><H><G><Q><F><S><E><A><E><E><H><I><I><V><K><F><H><S><V><L><G><N><R><W><S><L><I><A><A><Q><L><P><G><R><T><D><N><D><V><K><N><Y...
Transcription factor that binds to the DNA sequence 5'-CCAACC-3'. Regulates directly PME5, UND and GLOX1 . Essential for tapetum development in anthers and microsporogenesis . Regulates the timing of tapetal programmed cell death (PCD) which is critical for pollen development. May act through the activation of UND, enc...
Q9XHV0
A2A259
PK2L1_MOUSE
Polycystin-2 homolog
Mus
<M><N><S><M><E><S><P><K><N><Q><E><L><Q><T><L><G><N><R><A><W><D><N><P><A><Y><S><D><P><P><S><P><N><R><T><L><R><I><C><T><V><S><S><V><A><L><P><E><T><Q><P><K><K><P><E><V><R><C><Q><E><K><T><Q><R><T><L><V><S><S><C><C><L><H><I><C><R><S><I><R><G><L><W><G><T><T><L><T><E><N><T><A><E><N><R><E><L><Y><V><K><T><T><L><R><E><L><V><V><Y...
Pore-forming subunit of a heteromeric, non-selective cation channel that is permeable to Ca(2+) . Pore-forming subunit of a calcium-permeant ion channel formed by PKD1L2 and PKD1L1 in primary cilia, where it controls cilium calcium concentration, but does not affect cytoplasmic calcium concentration . The channel forme...
A2A259
Q5LTL1
SYM_RUEPO
Methionyl-tRNA synthetase
Ruegeria
<M><A><R><I><L><I><T><S><A><I><P><Y><I><N><G><I><K><H><L><G><N><L><V><G><S><Q><L><P><A><D><L><Y><A><R><Y><Q><R><G><R><G><N><E><V><M><F><L><C><A><T><D><E><H><G><T><P><A><E><L><A><A><A><K><A><G><K><P><V><A><E><Y><C><A><E><M><H><G><V><Q><A><D><I><A><R><R><F><G><L><S><F><D><H><F><G><R><S><S><S><A><Q><N><H><K><L><T><Q><H><F...
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.<BOP>
Q5LTL1
Q7WAK9
NORM_BORPA
Multidrug-efflux transporter
Bordetella
<M><P><R><S><T><A><R><A><A><W><K><R><E><L><A><A><T><L><A><L><G><L><P><L><V><L><T><N><L><A><Q><M><A><M><T><V><T><D><V><I><F><I><G><R><L><G><S><Q><A><L><A><A><S><A><L><G><A><N><L><F><T><A><I><E><F><F><G><L><G><L><V><A><A><T><A><P><M><V><A><H><A><L><G><R><R><G><N><T><V><R><D><V><R><R><T><V><R><Q><G><L><W><T><A><V><I><Y><S...
Multidrug efflux pump.<BOP>
Q7WAK9
Q6GPM3
TAT3B_XENLA
Putative deoxyribonuclease tatdn3-B
Xenopus
<M><A><R><S><V><V><L><V><D><C><H><W><H><L><T><A><S><E><F><D><H><D><I><G><S><V><L><E><D><A><K><T><I><G><L><C><A><L><V><A><V><A><E><H><S><G><E><F><E><K><V><I><E><L><S><R><R><N><A><G><L><V><F><P><C><L><G><V><H><P><V><Q><G><S><A><T><G><P><Q><R><S><A><T><L><Q><D><V><E><D><A><L><P><M><I><E><Q><Y><R><D><E><L><V><A><I><G><E><V...
Putative deoxyribonuclease.<BOP>
Q6GPM3
B0RTY0
CSRA_XANCB
Carbon storage regulator
Xanthomonas
<M><L><I><L><T><R><R><V><G><E><T><L><M><I><G><D><L><V><T><V><T><V><I><G><V><K><G><N><Q><V><R><I><G><I><A><A><P><K><H><V><A><V><H><R><E><E><I><Y><Q><R><I><Q><R><G><D><E><P><V><A><S><G><A><H><H><N><D><D><C><S><D>
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding...
B0RTY0
A1T8K1
RIBBA_MYCVP
GTP cyclohydrolase II
Mycolicibacterium
<M><T><R><L><D><S><V><E><R><A><V><A><D><I><A><A><G><K><A><V><V><V><I><D><D><E><D><R><E><N><E><G><D><L><I><F><A><A><E><K><A><T><P><E><L><V><A><F><M><V><R><Y><T><S><G><Y><L><C><V><P><L><A><G><D><I><C><D><R><L><G><L><L><P><M><Y><A><V><N><Q><D><K><H><G><T><A><Y><T><V><T><V><D><A><K><K><G><V><G><T><G><I><S><A><M><D><R><A><T...
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.<BOP>
A1T8K1
O60085
MAP2_SCHPO
Peptidase M
Schizosaccharomyces
<M><T><S><A><T><T><T><E><A><T><A><K><D><L><Q><E><K><L><S><L><K><E><N><D><V><V><E><D><D><G><K><V><E><E><N><D><A><A><E><E><G><A><S><N><G><E><K><K><K><K><K><K><K><K><S><S><K><K><K><K><T><P><Q><E><Q><T><N><P><P><T><V><G><L><S><K><I><F><V><N><K><K><Y><P><V><G><E><V><C><D><Y><A><E><D><N><L><W><R><T><T><D><E><E><K><R><A><L><D...
Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).<BOP>
O60085
A2BN21
RTCA_HYPBU
RNA 3'-terminal phosphate cyclase
Hyperthermus
<M><I><V><I><D><G><S><I><G><E><G><G><G><Q><I><L><R><T><T><L><A><L><A><A><L><L><G><K><P><V><R><I><V><N><I><R><A><K><R><P><R><P><G><L><Q><R><Q><H><L><T><S><V><K><A><V><A><E><L><A><S><A><R><V><E><G><L><E><L><G><S><T><T><L><V><F><I><P><R><G><L><R><S><G><R><F><Y><F><N><I><G><T><A><G><S><I><T><L><V><L><Q><A><L><L><P><V><T><A...
Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in...
A2BN21
B8JGW9
G6PI_ANAD2
Phosphohexose isomerase
Anaeromyxobacter
<M><P><D><R><T><G><P><L><L><R><T><P><A><W><R><A><L><E><A><H><L><A><E><L><Q><P><L><H><L><R><E><L><F><A><R><D><P><G><R><G><E><R><L><V><A><D><G><A><G><L><H><L><D><Y><S><K><Q><R><V><T><E><E><T><V><R><L><L><V><A><L><A><E><A><R><G><L><P><E><R><R><A><A><M><F><R><G><E><K><V><N><V><T><E><G><R><A><V><L><H><V><A><L><R><A><P><R><G...
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.<BOP>
B8JGW9
Q4ZSS5
MODC_PSEU2
Molybdenum import ATP-binding protein ModC
Pseudomonas syringae
<M><A><S><P><I><E><V><R><L><Q><M><A><Y><P><D><F><T><V><R><T><D><L><S><L><P><G><S><G><I><T><A><L><F><G><P><S><G><S><G><K><T><T><C><L><R><C><I><A><G><L><E><K><A><D><Q><S><F><I><R><V><H><D><E><V><W><Q><D><T><E><K><G><I><F><L><A><P><Y><K><R><A><I><G><Y><V><F><Q><E><A><S><L><F><A><H><L><S><V><R><D><N><L><E><F><G><M><K><R><I...
Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system.<BOP>
Q4ZSS5
Q07020
RL18_HUMAN
Large ribosomal subunit protein eL18
Homo
<M><G><V><D><I><R><H><N><K><D><R><K><V><R><R><K><E><P><K><S><Q><D><I><Y><L><R><L><L><V><K><L><Y><R><F><L><A><R><R><T><N><S><T><F><N><Q><V><V><L><K><R><L><F><M><S><R><T><N><R><P><P><L><S><L><S><R><M><I><R><K><M><K><L><P><G><R><E><N><K><T><A><V><V><V><G><T><I><T><D><D><V><R><V><Q><E><V><P><K><L><K><V><C><A><L><R><V><T><S...
Component of the large ribosomal subunit . The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell .<BOP>
Q07020
O94744
GIT3_SCHPO
Glucose-insensitive transcription protein 3
Schizosaccharomyces
<M><L><H><L><D><Y><T><F><N><V><S><D><A><T><S><T><S><S><I><I><I><V><S><R><R><E><L><A><N><L><R><I><M><V><I><I><A><S><A><I><S><I><V><F><S><L><I><A><I><F><W><R><W><S><R><R><R><T><I><R><E><Q><F><H><I><A><L><F><S><V><L><F><I><R><S><I><V><Q><M><I><H><P><C><L><A><L><S><D><P><F><F><W><A><P><K><H><R><C><F><T><I><G><F><F><L><L><V...
Activates gpa2 when triggered by glucose and then activates adenylate cyclase.<BOP>
O94744
O54803
P2RX6_MOUSE
Purinergic receptor P2X-like 1
Mus
<M><Q><L><Q><P><A><G><T><G><N><M><A><S><A><A><A><A><A><L><V><S><W><G><F><L><D><Y><K><T><E><K><Y><V><L><T><R><N><C><R><V><G><V><S><Q><R><L><L><Q><L><A><V><V><V><Y><V><I><G><W><A><L><L><A><K><K><G><Y><Q><E><R><D><L><A><P><Q><T><S><V><I><T><K><L><K><G><V><S><V><T><Q><V><K><E><L><E><N><R><L><W><D><V><A><D><F><V><K><P><S><Q...
Receptor for ATP that acts as a ligand-gated ion channel.<BOP>
O54803
Q3JCN4
RLMN_NITOC
tRNA m2A37 methyltransferase
Nitrosococcus
<M><T><D><S><R><T><N><L><L><N><L><D><R><A><G><L><D><A><F><F><T><C><L><G><E><K><P><F><R><A><R><Q><V><L><R><W><I><H><Q><R><F><V><T><D><F><S><A><M><T><D><L><N><K><S><L><R><E><R><L><T><E><S><A><V><I><S><L><P><E><I><I><K><Q><H><R><S><A><D><G><T><H><K><W><L><L><R><M><H><G><N><N><C><I><E><T><V><F><I><P><E><G><D><R><G><T><L><C...
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.<BOP>
Q3JCN4
Q8XXY9
NODI_RALSO
Nodulation ATP-binding protein I
Ralstonia
<M><R><Y><E><Q><P><P><G><P><G><I><G><S><T><P><I><L><S><V><E><G><L><R><K><R><Y><G><E><Q><T><V><V><D><G><L><S><F><S><V><R><R><G><Q><C><F><G><L><L><G><P><N><G><A><G><K><T><T><T><L><R><M><L><L><G><M><T><M><P><D><A><G><T><L><Q><L><C><G><E><T><I><P><G><H><A><H><R><A><R><M><R><V><G><V><V><P><Q><F><D><N><L><D><P><D><F><T><V><S...
Part of the ABC transporter complex NodIJ involved in the export of the nodulation factors (Nod factors), the bacterial signal molecules that induce symbiosis and subsequent nodulation induction. Nod factors are LCO (lipo-chitin oligosaccharide), a modified beta-1,4-linked N-acetylglucosamine oligosaccharide. This subu...
Q8XXY9
B1KZJ2
MNMA2_CLOBM
tRNA-specific 2-thiouridylase MnmA 2
Clostridium
<M><S><K><G><I><V><A><L><A><M><S><G><G><V><D><S><S><V><S><A><Y><I><L><K><E><R><G><Y><E><V><I><G><I><Y><M><D><L><W><R><D><E><R><E><E><Y><C><N><K><S><A><A><E><D><A><R><R><V><A><E><K><L><D><I><P><F><H><I><I><N><I><G><K><E><F><K><A><N><V><I><D><Y><F><I><D><E><Y><L><S><G><R><T><P><N><P><C><V><A><C><N><K><T><I><K><F><E><A><F...
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.<BOP>
B1KZJ2
P38927
REV7_YEAST
Revertibility protein 7
null
<M><N><R><W><V><E><K><W><L><R><V><Y><L><K><C><Y><I><N><L><I><L><F><Y><R><N><V><Y><P><P><Q><S><F><D><Y><T><T><Y><Q><S><F><N><L><P><Q><F><V><P><I><N><R><H><P><A><L><I><D><Y><I><E><E><L><I><L><D><V><L><S><K><L><T><H><V><Y><R><F><S><I><C><I><I><N><K><K><N><D><L><C><I><E><K><Y><V><L><D><F><S><E><L><Q><H><V><D><K><D><D><Q><I...
Required for DNA damage induced mutagenesis. Involved in DNA repair, mitochondrial DNA repair and translesion synthesis. Has a role in the bypass of abasic (AP) sites.<BOP>
P38927
A1TJ14
RL16_ACIAC
50S ribosomal protein L16
Acidovorax
<M><L><Q><P><A><R><R><K><Y><R><K><E><Q><K><G><R><N><T><G><V><A><T><R><G><N><S><V><A><F><G><D><F><G><L><K><C><T><D><R><G><R><L><T><A><R><Q><I><E><A><A><R><R><A><I><S><R><H><V><K><R><G><G><R><I><W><I><R><V><F><P><D><K><P><I><S><T><K><P><A><E><V><R><M><G><N><G><K><G><N><P><E><Y><Y><V><A><E><I><Q><P><G><K><I><V><F><E><I><V...
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.<BOP>
A1TJ14
A1KII1
METK_MYCBP
Methionine adenosyltransferase
Mycobacterium tuberculosis complex
<M><S><E><K><G><R><L><F><T><S><E><S><V><T><E><G><H><P><D><K><I><C><D><A><I><S><D><S><V><L><D><A><L><L><A><A><D><P><R><S><R><V><A><V><E><T><L><V><T><T><G><Q><V><H><V><V><G><E><V><T><T><S><A><K><E><A><F><A><D><I><T><N><T><V><R><A><R><I><L><E><I><G><Y><D><S><S><D><K><G><F><D><G><A><T><C><G><V><N><I><G><I><G><A><Q><S><P><D...
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.<BOP>
A1KII1
Q1MRQ0
RLME_LAWIP
rRNA (uridine-2'-O-)-methyltransferase
Lawsonia
<M><K><P><Y><R><D><Y><Y><F><L><K><A><K><H><E><K><Y><P><A><R><S><I><Y><K><L><K><E><I><D><N><R><F><C><L><F><Q><K><G><M><S><V><L><D><L><G><A><S><P><G><S><W><S><L><G><A><A><E><K><V><G><K><T><G><R><V><V><S><C><D><I><Q><T><I><T><I><P><L><P><S><N><V><S><F><F><Q><E><D><I><F><H><R><S><D><S><F><N><N><I><L><I><K><E><G><P><F><H><V...
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.<BOP>
Q1MRQ0
Q69B66
NU4LM_BALBN
NADH dehydrogenase subunit 4L
Balaenoptera
<M><T><L><I><H><M><N><I><L><M><A><F><S><M><S><L><V><G><L><L><M><Y><R><S><H><L><M><S><A><L><L><C><L><E><G><M><M><L><S><L><F><V><L><A><T><L><T><I><L><S><S><H><F><T><L><A><N><M><M><P><I><I><L><L><V><F><A><A><C><E><A><A><I><G><L><A><L><L><V><M><V><S><N><T><Y><G><T><D><Y><V><Q><S><L><N><L><L><Q><C>
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.<BOP>
Q69B66
B0UHW5
RS19_METS4
30S ribosomal protein S19
Methylobacterium
<M><A><R><S><V><W><K><G><P><F><V><D><G><Y><L><L><K><K><A><E><T><A><R><G><S><T><R><A><E><V><I><K><I><W><S><R><R><S><T><I><L><P><Q><F><V><G><L><T><F><G><V><Y><N><G><Q><K><H><I><P><V><Y><V><T><E><E><M><V><G><H><K><F><G><E><F><S><P><T><R><T><F><H><G><H><A><A><D><K><K><A><K><R><R>
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.<BOP>
B0UHW5
Q53B70
CF1B2_SOYBN
Chalcone--flavanone isomerase 1B-2
Glycine subgen. Soja
<M><A><T><P><A><S><I><T><N><V><T><V><E><F><L><Q><F><P><A><L><V><T><P><P><A><S><T><K><S><Y><F><L><G><G><A><G><V><R><G><L><N><I><Q><E><E><F><V><K><F><T><G><I><G><V><Y><L><E><D><K><A><V><S><S><L><G><A><K><W><K><G><K><S><A><A><E><L><L><D><S><L><D><F><Y><R><D><I><I><K><G><P><F><E><K><L><I><R><G><S><K><L><R><T><L><D><G><R><E...
Catalyzes the intramolecular cyclization of bicyclic chalcones into tricyclic (S)-flavanones. Responsible for the isomerization of 4,2',4',6'-tetrahydroxychalcone (also termed chalcone) into naringenin.<BOP>
Q53B70
Q92110
CP1A1_ONCMY
CYPIA1
Oncorhynchus
<M><V><L><M><I><L><P><I><I><G><S><V><S><V><S><E><G><L><V><A><I><V><T><L><C><L><V><Y><M><L><M><K><Y><K><H><T><E><I><P><E><G><L><K><R><L><P><G><P><K><P><L><P><I><I><G><N><V><L><E><V><Y><N><N><P><H><L><S><L><T><A><M><S><E><R><Y><G><S><V><F><Q><I><Q><I><G><M><R><P><V><V><V><L><S><G><N><E><T><V><R><Q><A><L><I><K><Q><G><E><D...
Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.<BOP>
Q92110
P46639
KNAT1_ARATH
Protein KNAT1
Arabidopsis
<M><E><E><Y><Q><H><D><N><S><T><T><P><Q><R><V><S><F><L><Y><S><P><I><S><S><S><N><K><N><D><N><T><S><D><T><N><N><N><N><N><N><N><N><S><S><N><Y><G><P><G><Y><N><N><T><N><N><N><N><H><H><H><Q><H><M><L><F><P><H><M><S><S><L><L><P><Q><T><T><E><N><C><F><R><S><D><H><D><Q><P><N><N><N><N><N><P><S><V><K><S><E><A><S><S><S><R><I><N><H><Y...
May play a role in meristem function, and may be involved in maintaining cells in an undifferentiated, meristematic state, and its expression disappears at the same time the shoot apex undergoes the transition from vegetative to reproductive development . Positive regulator of LATERAL ORGAN BOUNDARIES (LOB) . Probably ...
P46639
Q3B725
ZBT24_RAT
Zinc finger protein 450
Rattus
<M><A><D><T><T><P><E><P><S><G><H><L><I><V><H><S><D><T><H><S><D><T><V><L><A><S><L><E><D><Q><R><K><K><G><F><L><C><D><I><T><L><I><V><E><N><V><H><F><R><A><H><K><A><L><L><A><A><S><S><E><Y><F><S><M><M><F><A><E><E><G><E><I><G><Q><S><I><Y><M><L><E><G><M><V><A><D><T><F><G><I><L><L><E><F><I><Y><T><G><Y><L><H><A><S><E><K><M><T><E...
May be involved in BMP2-induced transcription.<BOP>
Q3B725
Q87SU4
RL21_VIBPA
50S ribosomal protein L21
Vibrio
<M><Y><A><V><F><Q><S><G><G><K><Q><H><R><V><S><E><G><Q><T><L><R><L><E><K><L><D><V><E><T><G><A><T><V><E><F><D><K><V><L><L><V><A><N><G><E><D><I><K><V><G><A><P><L><V><E><G><G><K><I><V><A><E><V><V><Q><H><G><R><G><D><K><V><K><I><V><K><F><R><R><R><K><H><S><R><K><Q><Q><G><H><R><Q><W><F><T><E><V><K><I><T><G><I><N><A>
This protein binds to 23S rRNA in the presence of protein L20.<BOP>
Q87SU4
A7Z939
CLPP_BACVZ
Endopeptidase Clp
Bacillus amyloliquefaciens group
<M><N><L><I><P><T><V><I><E><Q><T><N><R><G><E><R><A><Y><D><I><Y><S><R><L><L><K><D><R><I><I><M><L><G><S><A><I><D><D><N><V><A><N><S><I><V><S><Q><L><L><F><L><E><A><E><D><P><E><K><D><I><S><I><Y><I><N><S><P><G><G><S><I><T><A><G><M><A><I><Y><D><T><M><Q><F><I><K><P><K><V><S><T><I><C><I><G><M><A><A><S><M><G><A><F><L><L><A><A><G...
Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.<BOP>
A7Z939
Q3KJI8
HIS5_PSEPF
ImGP synthase subunit HisH
Pseudomonas
<M><Q><T><V><A><V><I><D><Y><G><M><G><N><L><H><S><V><A><K><A><L><E><H><V><G><A><G><K><V><L><I><T><S><D><A><A><V><I><R><E><A><D><R><V><V><F><P><G><V><G><A><I><R><D><C><M><A><E><I><R><R><L><G><F><D><S><L><V><R><E><V><S><Q><D><R><P><F><L><G><I><C><V><G><M><Q><A><L><L><D><S><S><E><E><N><D><G><V><D><C><I><G><L><F><P><G><A><V...
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.<BOP>
Q3KJI8
B4SE23
ISPF_PELPB
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Pelodictyon
<M><R><I><G><I><G><I><D><V><H><P><F><A><E><G><R><K><L><V><I><G><G><V><H><I><P><G><H><N><G><L><D><G><H><S><D><A><D><V><L><L><H><A><V><S><D><A><L><L><G><A><A><A><L><G><D><I><G><L><H><F><P><N><T><S><Q><E><F><K><D><I><D><S><M><I><L><L><K><Q><V><R><K><L><L><E><K><H><G><Y><Q><T><V><N><I><D><A><M><L><L><L><E><E><P><K><I><A><P...
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a correspond...
B4SE23
O80690
BGL46_ARATH
Beta-glucosidase 46
Arabidopsis
<M><K><T><F><A><N><F><A><I><L><F><L><L><Q><S><L><L><F><P><L><Y><S><S><C><L><H><Q><T><S><D><D><S><S><P><F><P><S><D><F><L><F><G><T><A><S><S><A><F><Q><Y><E><G><A><F><L><T><D><G><K><G><L><N><N><W><D><V><F><A><H><E><N><P><G><K><I><V><D><G><S><N><G><D><I><A><T><D><Q><Y><H><R><Y><M><E><D><I><Q><S><M><N><F><L><G><V><N><S><Y><R...
Hydrolyzes p-nitrophenyl beta-D-glucoside, p-nitrophenyl beta-D-galactoside and natural glucosides such as salicin, p-coumaryl alcohol glucoside, phenyl-beta-D-glucoside, coniferin, syringin and arbutin. May be involved in lignification by hydrolyzing monolignol glucosides.<BOP>
O80690
P9WFR0
GLTR2_MYCTO
PGL/p-HBAD biosynthesis glycosyltransferase MT3034
Mycobacterium tuberculosis complex
<M><E><E><T><S><V><A><G><D><P><G><P><D><A><G><T><S><T><A><P><N><A><A><P><E><P><V><A><R><R><Q><R><I><L><F><V><G><E><A><A><T><L><A><H><V><V><R><P><F><V><L><A><R><S><L><D><P><S><R><Y><E><V><H><F><A><C><D><P><R><F><N><K><L><L><G><P><L><P><F><P><H><H><P><I><H><T><V><P><S><E><E><V><L><L><K><I><A><Q><G><R><L><F><Y><N><T><R><T...
Involved in glycosylation steps downstream of mono-O-methyl-glycosyl-p-hydroxybenzoic acid derivative (p-HBAD I) and 2-O-methyl-rhamnosyl-phenolphthiocerol dimycocerosate (mycoside B) during the p-hydroxybenzoic acid derivatives (p-HBAD) and glycosylated phenolphthiocerol dimycocerosates (PGL) biosynthesis.<BOP>
P9WFR0
Q8YJF0
DAPF_BRUME
PLP-independent amino acid racemase
Brucella
<M><A><T><K><A><A><F><A><R><M><N><G><L><G><N><Q><I><I><V><A><D><M><R><G><R><A><D><S><I><T><S><A><A><A><I><R><L><A><S><D><S><E><T><A><F><D><Q><I><M><A><I><H><D><P><R><T><P><G><T><D><Y><Y><I><A><I><I><N><C><D><G><T><Q><A><Q><A><C><G><N><G><T><R><C><V><V><Q><A><L><A><A><E><T><G><R><H><A><F><T><F><E><T><R><A><G><I><L><T><A...
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.<BOP>
Q8YJF0
Q5WFL1
RSGA_ALKCK
Small ribosomal subunit biogenesis GTPase RsgA
Alkalihalobacillus
<M><P><E><G><L><I><V><K><A><L><S><G><F><Y><Y><V><Q><S><E><G><A><L><I><Q><C><R><G><R><G><V><F><R><K><R><K><Q><T><P><L><V><G><D><Y><V><E><F><E><A><E><N><E><T><D><G><Y><V><M><A><I><K><E><R><K><N><Q><L><N><R><P><P><I><A><N><V><D><Q><A><I><L><V><F><S><A><K><E><P><D><F><H><T><L><L><L><D><R><F><L><V><H><I><E><Q><H><D><I><K><P...
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimula...
Q5WFL1
B5RM04
SYDND_BORDL
Non-discriminating aspartyl-tRNA synthetase
Borrelia
<M><F><K><I><I><K><C><N><Q><I><N><N><K><L><I><N><K><K><I><E><I><N><G><W><V><K><K><I><R><N><H><G><K><V><T><F><I><N><I><R><D><R><Y><D><E><A><Q><I><L><V><S><D><E><K><L><L><K><I><T><S><Q><I><K><M><E><Y><C><I><K><I><Q><G><K><L><N><L><R><P><L><E><L><V><N><R><E><M><K><T><G><E><L><E><I><I><A><E><N><I><D><I><I><S><K><C><N><E><L...
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).<BOP>
B5RM04
B0TZ67
FETP_FRAP2
Probable Fe(2+)-trafficking protein
Francisella
<M><T><K><V><L><C><K><K><Y><N><E><E><L><D><A><I><P><F><Q><P><L><P><G><E><L><G><K><K><I><H><S><E><I><S><N><K><A><W><Q><A><W><L><A><H><Q><T><I><L><I><N><E><Y><R><L><N><L><I><E><P><K><A><K><E><F><L><K><E><E><M><Q><K><F><L><F><E><N><K><E><D><K><P><E><Q><F><N><E><I>
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.<BOP>
B0TZ67
B2V1Q9
RLMH_CLOBA
rRNA (pseudouridine-N3-)-methyltransferase RlmH
Clostridium
<M><N><I><T><I><I><S><V><G><K><L><K><E><K><Y><L><K><H><A><I><D><E><Y><S><K><R><L><S><R><Y><C><K><L><N><I><V><E><L><Q><D><E><Q><T><P><D><N><A><S><E><K><D><E><L><I><I><K><D><K><E><G><N><K><I><L><N><S><I><K><D><N><M><Y><V><I><T><L><D><L><K><G><K><M><I><S><S><E><E><L><S><K><F><I><D><N><C><G><V><R><G><N><S><N><L><C><F><I><I...
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.<BOP>
B2V1Q9
I6YCF5
IPDE2_MYCTU
5OH-HIP-CoA dehydrogenase beta subunit
Mycobacterium tuberculosis complex
<M><T><P><P><E><E><R><Q><M><L><R><E><T><V><A><S><L><V><A><K><H><A><G><P><A><A><V><R><A><A><M><A><S><D><R><G><Y><D><E><S><L><W><R><L><L><C><E><Q><V><G><A><A><A><L><V><I><P><E><E><L><G><G><A><G><G><E><L><A><D><A><A><I><V><V><Q><E><L><G><R><A><L><V><P><S><P><L><L><G><T><T><L><A><E><L><A><L><L><A><A><A><K><P><D><A><Q><A><L...
Involved in cholesterol degradation. Catalyzes the dehydrogenation of 5OH-HIP-CoA to 5OH-HIPE-CoA . Can also use octanoyl-CoA and dihydroferuloyl-CoA, with lower efficiency. Cannot use 3-oxo-4-pregnene-20-carboxyl-CoA (3-OPC-CoA) .<BOP>
I6YCF5
Q95727
CYB_ARTFR
Ubiquinol-cytochrome-c reductase complex cytochrome b subunit
Artibeus
<M><T><N><I><R><K><T><H><P><L><L><K><I><I><N><S><S><F><V><D><L><P><A><P><S><S><L><S><S><W><W><N><F><G><P><F><L><G><V><C><L><G><V><Q><I><L><T><G><L><F><L><A><M><H><Y><T><S><D><T><A><T><A><F><N><S><V><T><H><I><C><R><D><V><N><Y><G><W><L><L><R><Y><L><H><A><N><G><A><S><M><F><F><I><C><L><Y><L><H><V><G><R><G><L><Y><Y><G><S><Y...
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is...
Q95727
Q0I4E6
PRIB_HAES1
Primosomal replication protein N
Histophilus
<M><L><K><S><N><L><E><V><D><N><R><F><S><L><I><G><K><V><A><D><F><P><K><R><N><K><S><P><S><G><I><D><H><C><L><F><Y><L><E><H><R><S><N><K><K><E><A><G><F><T><R><Q><A><W><C><K><I><A><I><Q><I><S><G><N><Q><L><I><E><K><T><Q><S><I><T><V><G><Q><Q><L><L><V><V><G><F><V><T><S><H><R><S><S><N><G><L><N><Q><L><V><L><H><A><E><Q><I><E><F><I...
Binds single-stranded DNA at the primosome assembly site (PAS).<BOP>
Q0I4E6
Q92JC9
ENGB_RICCN
Probable GTP-binding protein EngB
spotted fever group
<M><T><T><Q><K><I><V><P><T><K><S><T><D><G><S><K><L><F><R><H><Q><A><K><F><V><A><G><A><M><N><I><N><Q><I><L><N><F><S><L><P><E><I><A><F><V><G><K><S><N><V><G><K><S><S><L><I><N><T><I><C><N><N><K><N><L><A><K><V><S><N><T><P><G><R><T><R><Q><I><N><F><F><N><L><A><D><K><L><I><I><V><D><L><P><G><Y><G><F><A><N><V><P><I><S><V><K><E><Q...
Necessary for normal cell division and for the maintenance of normal septation.<BOP>
Q92JC9
A6T9H1
PQQC_KLEP7
Pyrroloquinoline quinone biosynthesis protein C
Klebsiella
<M><L><I><T><D><T><L><S><P><Q><A><F><E><E><A><L><R><A><K><G><D><F><Y><H><I><H><H><P><Y><H><I><A><M><H><N><G><N><A><T><R><E><Q><I><Q><G><W><V><A><N><R><F><Y><Y><Q><T><T><I><P><L><K><D><A><A><I><M><A><N><C><P><D><A><Q><T><R><R><K><W><V><Q><R><I><L><D><H><D><G><S><H><G><E><D><G><G><I><E><A><W><L><R><L><G><E><A><V><G><L><S...
Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.<BOP>
A6T9H1
Q2S4Q4
ISPE_SALRD
4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase
Salinibacter
<M><P><L><A><Q><D><A><P><A><K><I><N><L><G><L><H><V><L><R><R><R><P><D><G><Y><H><D><I><E><T><V><L><H><R><I><D><W><A><D><T><I><T><A><T><P><A><D><T><L><S><L><T><C><S><D><P><S><L><P><T><D><R><D><N><L><C><L><Q><A><A><H><R><L><A><S><A><C><D><V><P><A><G><A><D><L><H><L><E><K><R><V><P><Y><G><A><G><L><G><S><G><S><S><D><A><A><A><T...
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.<BOP>
Q2S4Q4
P27353
MEMA_METTR
Methane hydroxylase
Methylosinus
<M><A><I><S><L><A><T><K><A><A><T><D><A><L><K><V><N><R><A><P><V><G><V><E><P><Q><E><V><H><K><W><L><Q><S><F><N><W><D><F><K><E><N><R><T><K><Y><P><T><K><Y><H><M><A><N><E><T><K><E><Q><F><K><V><I><A><K><E><Y><A><R><M><E><A><A><K><D><E><R><Q><F><G><T><L><L><D><G><L><T><R><L><G><A><G><N><K><V><H><P><R><W><G><E><T><M><K><V><I><S...
Responsible for the initial oxygenation of methane to methanol in methanotrophs. It also catalyzes the monohydroxylation of a variety of unactivated alkenes, alicyclic, aromatic and heterocyclic compounds.<BOP>
P27353
Q5BKW7
ENPP6_DANRE
Ectonucleotide pyrophosphatase/phosphodiesterase family member 6
Danio
<M><T><R><T><L><L><K><I><Y><T><L><F><I><L><L><L><C><R><Q><R><D><A><N><R><K><L><L><V><F><L><I><D><G><F><R><H><D><Y><M><D><D><L><H><N><L><P><G><F><R><E><I><V><E><N><G><V><K><V><D><Y><L><T><P><D><F><P><S><L><S><Y><P><N><Y><Y><S><L><M><T><G><R><H><C><E><V><H><Q><M><T><G><N><Y><M><W><D><T><D><T><Q><K><E><F><L><I><G><T><N><P...
Choline-specific glycerophosphodiesterase that hydrolyzes glycerophosphocholine (GPC) and lysophosphatidylcholine (LPC) and contributes to supplying choline to the cells. Has a preference for LPC with short (12:0 and 14:0) or polyunsaturated (18:2 and 20:4) fatty acids. In vitro, hydrolyzes only choline-containing lyso...
Q5BKW7
Q72X39
AZOR4_BACC1
FMN-dependent NADH-azoreductase 4
Bacillus cereus group
<M><A><T><V><L><F><V><K><A><N><N><R><P><A><E><Q><A><V><S><V><K><L><Y><E><A><F><L><A><N><Y><K><E><A><H><P><N><D><T><V><V><E><L><D><L><Y><K><E><E><L><P><Y><V><G><V><D><M><I><N><G><T><F><K><A><G><K><G><F><D><L><T><E><E><E><A><K><A><V><A><V><A><D><K><Y><L><N><Q><F><L><E><A><D><K><V><V><F><G><F><P><L><W><N><L><T><I><P><A><V...
Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.<BOP>
Q72X39
A7GMU3
LEUC_BACCN
Isopropylmalate isomerase
Bacillus cereus group
<M><G><K><R><L><L><D><K><L><W><E><K><H><I><V><A><T><N><E><N><G><L><D><L><L><Y><I><D><L><H><L><V><H><E><V><T><S><P><Q><A><F><E><G><L><R><L><A><N><R><T><V><R><R><P><D><L><T><F><A><T><M><D><H><N><I><P><T><K><D><V><W><N><I><T><D><H><I><A><K><Q><Q><L><D><T><L><R><A><N><C><K><Q><F><H><I><S><L><A><D><I><G><D><E><A><Q><G><I><V...
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.<BOP>
A7GMU3
A1AUZ4
NADA_PELPD
Quinolinate synthase
Pelobacter
<M><N><N><G><I><K><E><Q><I><R><E><L><L><K><Q><H><N><A><V><L><L><A><H><N><Y><M><R><D><E><V><Q><E><I><A><D><I><T><G><D><S><L><A><L><S><I><E><A><A><K><T><E><A><D><V><I><V><F><C><G><V><H><F><M><A><E><S><A><A><I><L><S><P><D><K><K><V><L><L><P><R><L><D><A><G><C><P><M><A><D><M><V><D><A><R><G><L><E><E><L><K><K><K><H><P><G><V><P...
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.<BOP>
A1AUZ4
Q7NPF2
PDXJ_GLOVI
Pyridoxine 5'-phosphate synthase
Gloeobacter
<M><P><T><L><G><V><N><I><D><H><V><A><T><I><R><Q><A><R><R><T><V><E><P><D><P><A><A><A><A><V><L><V><E><L><A><G><A><D><G><I><T><V><H><L><R><E><D><R><R><H><I><Q><D><R><D><V><E><I><L><R><R><T><V><R><T><H><L><N><L><E><M><A><A><T><R><A><M><V><D><F><A><L><D><V><R><P><D><Y><V><T><L><V><P><E><R><R><E><E><V><T><T><E><G><G><L><D><V...
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.<BOP>
Q7NPF2
A8AZJ9
RPOA_STRGC
Transcriptase subunit alpha
Streptococcus
<M><I><E><F><E><K><P><N><I><T><K><I><D><E><N><K><D><Y><G><K><F><V><V><E><P><L><E><R><G><Y><G><T><T><L><G><N><S><L><R><R><V><L><L><A><S><L><P><G><A><A><V><T><S><I><N><I><E><G><V><L><H><E><F><D><T><I><P><G><V><R><E><D><V><M><Q><I><I><L><N><I><K><G><I><A><V><K><S><Y><V><Q><D><E><K><M><I><E><L><D><V><E><G><P><A><E><I><T><A...
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.<BOP>
A8AZJ9
Q9DBD0
ICA_MOUSE
Inhibitor of carbonic anhydrase
Mus
<M><R><L><L><I><C><A><L><L><C><L><G><T><L><G><L><C><L><A><L><P><E><K><T><I><R><W><C><V><V><S><D><H><E><A><T><K><C><S><S><F><R><D><N><M><K><K><V><L><P><A><G><G><P><A><V><T><C><V><R><K><M><S><H><P><E><C><I><R><D><I><S><A><N><K><V><D><A><V><T><V><D><G><A><L><V><A><E><A><D><L><P><H><H><S><L><K><P><I><M><A><E><Y><Y><G><S><K...
Inhibitor for carbonic anhydrase 2 (CA2). Does not bind iron ions.<BOP>
Q9DBD0
Q9A706
RRF_CAUVC
Ribosome-releasing factor
Caulobacter
<M><A><A><A><E><K><P><V><L><S><R><Y><R><D><R><M><D><K><A><V><S><A><L><K><E><E><F><G><S><L><R><T><G><R><A><S><A><S><L><L><D><Q><V><M><V><E><A><Y><G><S><T><T><P><L><N><A><V><A><S><V><S><V><P><E><P><R><Q><I><N><V><S><V><W><D><R><G><V><V><V><S><V><E><K><A><I><R><A><S><G><L><G><L><N><P><V><V><E><G><Q><N><L><R><I><P><I><P><P...
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.<BOP>
Q9A706
Q65SB8
ISPE_MANSM
4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase
Basfia
<M><K><T><H><Q><F><S><T><A><L><F><S><D><Y><K><Q><G><D><S><F><N><F><P><C><P><A><K><L><N><L><F><L><Y><I><N><G><R><R><T><D><G><Y><H><E><L><Q><T><L><F><Q><F><L><D><Y><G><D><W><L><S><I><K><V><R><N><D><G><K><I><R><L><T><P><E><I><P><D><L><K><T><E><D><N><L><I><Y><R><A><A><K><L><L><Q><Q><K><T><A><C><R><L><G><A><D><L><H><L><D><K...
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.<BOP>
Q65SB8
Q4R708
NAA35_MACFA
Protein MAK10 homolog
Macaca
<M><V><M><K><A><S><V><D><D><D><D><S><G><W><E><L><S><M><P><E><K><M><E><K><S><N><T><N><W><V><D><I><T><Q><D><F><E><E><A><C><R><E><L><K><L><G><E><L><L><H><D><K><L><F><G><L><F><E><A><M><S><A><I><E><M><M><D><P><K><M><D><A><G><M><I><G><N><Q><V><N><R><K><V><L><N><F><E><Q><A><I><K><D><G><T><I><K><I><K><D><L><T><L><P><E><L><I><G...
Auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues. Involved in regulation of apoptosis and proliferation of smooth muscle cells.<BOP>
Q4R708
Q6EW23
PSBH_NYMAL
Photosystem II 10 kDa phosphoprotein
Nymphaea
<M><A><T><Q><T><I><E><G><S><S><R><S><G><P><R><R><T><I><V><G><D><L><L><K><P><L><N><S><E><Y><G><K><V><A><P><G><W><G><T><T><P><L><M><G><V><A><M><A><L><F><A><V><F><L><S><I><I><L><E><I><Y><N><S><S><V><L><L><D><G><I><S><L><S>
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly. PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a c...
Q6EW23
Q8EIM7
RIHA_SHEON
Cytidine/uridine-specific hydrolase
Shewanella
<M><T><C><P><I><I><L><D><C><D><P><G><H><D><D><A><I><A><L><I><L><A><L><A><H><P><D><L><V><P><L><A><V><T><T><S><A><G><N><Q><T><P><D><K><T><L><N><N><A><L><R><I><L><T><L><L><N><R><S><D><I><P><V><A><G><G><A><A><K><P><L><A><R><D><L><I><I><A><D><N><V><H><G><E><T><G><L><D><G><P><A><L><P><N><P><S><F><S><P><Q><A><I><T><A><V><E><L...
Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively.<BOP>
Q8EIM7
D2Y2J4
H2U01_CYRHA
Hainantoxin-II-21
Haplopelma
<M><K><V><T><L><I><A><I><L><T><C><A><A><V><L><V><L><H><T><T><A><A><E><E><L><E><A><E><S><Q><L><V><E><V><G><M><P><D><T><E><L><A><A><V><D><E><E><R><F><F><E><C><S><V><S><C><E><I><E><K><E><G><N><K><D><C><K><K><K><K><C><K><G><G><W><K><C><K><F><N><M><C><V><K><V>
Postsynaptic neurotoxin.<BOP>
D2Y2J4
Q2K9L7
RS10_RHIEC
30S ribosomal protein S10
Rhizobium
<M><N><G><Q><N><I><R><I><R><L><K><A><F><D><H><R><I><L><D><A><S><T><R><E><I><V><S><T><A><K><R><T><G><A><S><V><R><G><P><V><P><L><P><T><R><I><E><K><F><T><V><N><R><S><P><H><I><D><K><K><S><R><E><Q><F><E><M><R><T><H><K><R><L><L><D><I><V><D><P><T><P><Q><T><V><D><A><L><M><K><L><D><L><A><A><G><V><D><V><E><I><K><L>
Involved in the binding of tRNA to the ribosomes.<BOP>
Q2K9L7
C3PDM2
GCSH_BACAA
Octanoyl/lipoyl carrier protein
Bacillus cereus group
<M><S><I><P><N><N><L><R><Y><S><E><E><H><E><W><V><K><T><E><G><N><E><V><V><I><G><I><T><H><F><A><Q><N><E><L><G><D><I><V><F><V><E><L><P><E><V><G><A><T><I><E><A><D><E><P><F><G><S><V><E><S><V><K><T><V><S><E><L><Y><A><P><V><S><G><K><V><V><A><V><N><E><E><L><S><D><Q><P><E><L><V><N><E><S><P><Y><E><G><A><W><M><V><K><V><E><L><S><D...
Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate.<BOP>
C3PDM2
Q0BQ80
MODC_GRABC
Molybdenum import ATP-binding protein ModC
Granulibacter
<M><S><S><A><A><L><E><V><R><L><N><H><R><F><P><G><T><E><I><D><V><C><F><A><G><R><G><C><T><V><L><F><G><P><S><G><A><G><K><S><T><I><A><M><A><V><A><G><L><M><R><P><D><H><L><H><L><R><V><G><G><L><D><L><H><D><L><P><P><E><R><R><R><I><G><V><V><F><Q><D><A><R><L><F><P><H><L><S><V><L><G><N><L><E><Y><G><A><R><R><A><P><P><G><D><F><P><L...
Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system.<BOP>
Q0BQ80
A6Q1H9
RL4_NITSB
50S ribosomal protein L4
unclassified Nitratiruptor
<M><S><K><A><V><V><L><N><E><N><F><E><K><A><S><E><V><A><L><P><E><H><F><Q><G><I><N><P><H><N><L><Y><L><Y><A><K><A><Y><A><A><N><L><R><A><N><N><A><H><T><K><S><R><G><E><V><S><G><G><G><R><K><P><W><Q><Q><K><G><R><G><G><A><R><A><G><S><I><R><S><P><L><F><V><G><G><G><V><A><F><G><P><K><N><T><K><N><Y><T><Q><K><V><N><K><K><Q><K><R><K...
Forms part of the polypeptide exit tunnel.<BOP>
A6Q1H9
Q164J6
AROB_ROSDO
3-dehydroquinate synthase
Roseobacter
<M><L><D><T><V><R><V><D><L><P><G><R><A><Y><D><V><R><I><G><S><G><L><L><P><E><A><G><G><H><V><L><P><L><L><K><R><P><R><V><A><V><V><T><D><E><T><V><A><G><L><H><L><E><A><L><R><A><G><L><A><R><D><G><I><E><M><S><A><L><A><L><P><A><G><E><A><T><K><S><W><A><P><L><E><R><T><V><G><W><L><L><D><Q><K><V><E><R><G><D><V><V><V><A><F><G><G><G...
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).<BOP>
Q164J6
P03825
GSPB_ECOLI
Putative general secretion pathway protein B
Escherichia
<M><F><E><F><Y><I><A><A><R><E><Q><K><E><T><G><H><P><G><I><F><S><R><Q><K><H><S><T><I><I><Y><V><I><C><L><L><L><I><C><L><W><F><A><G><M><V><L><V><G><G><Y><A><R><Q><L><W><V><L><W><I><V><K><A><E><V><T><V><E><A><E><T><P><A><F><K><Q><S><T><Q><H><Y><F><F><K><K><Q><P><L><P><V><V><E><S><V><E><E><E><D><D><P><G><V><A><V><E><N><A><P...
Part of a cryptic operon that encodes proteins involved in type II secretion pathway in other organisms, but is not expressed in strain K12 under standard laboratory conditions . May play a regulatory role under conditions of derepressed gsp gene expression .<BOP>
P03825
C5BE98
LFTR_EDWI9
Phenyalanyltransferase
Edwardsiella
<M><R><I><M><Q><L><D><R><H><S><L><G><F><P><S><P><E><Q><A><L><H><D><P><N><G><L><L><A><I><G><G><D><L><Q><P><A><R><L><L><Q><A><Y><Q><R><G><I><F><P><W><F><S><P><G><E><L><I><L><W><W><S><P><D><P><R><A><V><L><V><P><Q><A><L><H><I><S><H><S><L><R><K><A><L><R><R><T><T><L><R><I><T><L><N><Q><A><F><A><A><V><I><A><G><C><A><E><Q><R><A...
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.<BOP>
C5BE98
O68586
LANN_STRMG
Mutacin III
Streptococcus
<M><S><N><T><Q><L><L><E><V><L><G><T><E><T><F><D><V><Q><E><D><L><F><A><F><D><T><T><D><T><T><I><V><A><S><N><D><D><P><D><T><R><F><K><S><W><S><L><C><T><P><G><C><A><R><T><G><S><F><N><S><Y><C><C>
Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores.<BOP>
O68586
Q6R8G6
PHO14_ARATH
Protein PHO1 homolog 4
Arabidopsis
<M><R><F><G><K><E><F><V><S><Q><M><I><P><E><W><Q><E><A><Y><I><D><Y><A><Y><L><K><T><I><L><Q><D><I><Q><A><S><R><N><R><S><D><S><N><N><Q><S><S><T><P><S><F><A><R><N><L><T><R><R><Y><N><R><D><A><L><V><S><E><N><H><D><I><V><V><N><T><V><T><R><L><E><E><G><L><E><T><A><A><Y><E><T><T><F><L><K><A><G><E><A><G><G><D><F><E><V><T><F><F><R...
May transport inorganic phosphate (Pi).<BOP>
Q6R8G6
D3RX66
PSB_FERPA
Proteasome core protein PsmB
Ferroglobus
<M><I><H><D><K><V><F><K><G><T><T><T><V><G><L><V><C><K><D><G><V><V><L><A><T><E><K><R><A><T><M><G><N><F><I><A><S><R><R><A><K><K><I><Y><K><I><T><D><R><I><A><M><T><T><A><G><S><V><G><D><A><Q><F><L><A><R><L><I><K><V><E><T><N><L><Y><T><I><R><K><E><E><E><P><T><V><K><A><V><A><T><L><V><S><N><L><L><N><S><V><R><Y><F><P><Y><L><V><Q...
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.<BOP>
D3RX66
Q607A2
NADK_METCA
ATP-dependent NAD kinase
Methylococcus
<M><P><S><Q><F><R><T><I><A><L><I><G><K><P><D><A><P><R><I><A><D><T><L><A><A><I><H><S><Y><L><L><T><S><G><L><E><I><L><V><E><H><G><C><A><G><L><F><P><R><S><A><R><T><G><T><M><P><E><L><A><R><Q><A><D><I><A><V><V><V><G><G><D><G><T><L><L><G><A><A><R><S><L><Y><A><H><G><V><P><L><V><G><I><N><L><G><R><L><G><F><L><V><D><I><S><P><N><E...
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.<BOP>
Q607A2
Q28I80
YLAT2_XENTR
y(+)L-type amino acid transporter 2
Silurana
<M><K><E><T><E><N><Q><T><V><P><L><N><S><T><S><P><G><D><T><S><H><T><S><T><S><D><S><K><D><P><Q><D><T><M><Q><L><K><K><E><I><S><L><L><N><G><V><S><L><I><V><G><N><M><I><G><S><G><I><F><V><S><P><K><G><V><L><I><Y><S><A><S><Y><G><L><S><L><I><L><W><S><L><G><G><I><F><S><V><I><G><A><L><C><Y><A><E><L><G><T><T><I><K><K><S><G><A><S><Y...
Involved in the sodium-independent uptake of dibasic amino acids and sodium-dependent uptake of some neutral amino acids.<BOP>
Q28I80
Q71F23
CENPU_HUMAN
Polo-box-interacting protein 1
Homo
<M><A><P><R><G><R><R><R><P><R><P><H><R><S><E><G><A><R><R><S><K><N><T><L><E><R><T><H><S><M><K><D><K><A><G><Q><K><C><K><P><I><D><V><F><D><F><P><D><N><S><D><V><S><S><I><G><R><L><G><E><N><E><K><D><E><E><T><Y><E><T><F><D><P><P><L><H><S><T><A><I><Y><A><D><E><E><E><F><S><K><H><C><G><L><S><L><S><S><T><P><P><G><K><E><A><K><R><S...
Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA in...
Q71F23
P54466
FLOA_BACSU
Flotillin-like protein FloA
Bacillus
<M><D><P><S><T><L><M><I><L><A><I><V><A><V><A><I><I><V><L><A><V><F><F><T><F><V><P><V><M><L><W><I><S><A><L><A><A><G><V><K><I><S><I><F><T><L><V><G><M><R><L><R><R><V><I><P><N><R><V><V><N><P><L><I><K><A><H><K><A><G><L><N><V><G><T><N><Q><L><E><S><H><Y><L><A><G><G><N><V><D><R><V><V><N><A><L><I><A><A><Q><R><A><N><I><E><L><T><F...
Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts. FMMs are highly dynamic and increase in number as cells age. FloA and FloT function is partially redundant; double deletions have marked synthetic phenotypes . Flotillins are thought to be important factors in membrane ...
P54466
Q68Y04
FER_RICTY
Ferredoxin
typhus group
<M><T><Y><I><V><T><D><E><C><V><K><C><K><Y><T><D><C><V><E><V><C><P><V><D><C><F><Y><E><G><E><F><M><L><V><I><N><P><D><E><C><I><D><C><G><V><C><V><P><D><C><P><I><D><A><I><K><P><E><S><P><E><L><I><E><W><V><E><R><A><K><D><F><I><E><N><Q><G><W><K><N><I><T><K><K><K><C><A><L><P><D><A><D><K><F><K><D><E><Q><D><K><F><N><K><Y><I><I><K...
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.<BOP>
Q68Y04
Q6TCG5
PAQR6_MOUSE
Progestin and adipoQ receptor family member VI
Mus
<M><L><S><L><K><M><P><Q><L><L><R><V><H><Q><V><P><R><V><F><W><E><E><G><I><M><S><G><Y><R><C><P><T><S><S><A><L><D><C><V><L><S><S><F><Q><M><T><N><E><T><V><N><I><W><T><H><F><L><P><T><W><Y><F><L><W><R><L><L><A><L><G><S><P><G><F><R><A><D><P><Y><H><L><P><L><L><V><F><L><L><P><A><C><L><Y><P><F><A><S><C><C><A><H><T><F><S><S><M><S...
Plasma membrane progesterone (P4) receptor coupled to G proteins. Seems to act through a G(s) mediated pathway. Involved in neurosteroid inhibition of apoptosis. May be involved in regulating rapid P4 signaling in the nervous system. Also binds dehydroepiandrosterone (DHEA), pregnanolone, pregnenolone and allopregnanol...
Q6TCG5
A9B5I2
HIS5_HERA2
ImGP synthase subunit HisH
Herpetosiphon
<M><I><A><V><I><N><Y><G><A><G><N><L><P><N><A><V><R><A><L><E><Y><V><Q><A><P><I><E><V><V><T><D><P><A><A><V><R><A><A><Q><A><V><V><L><P><G><V><G><A><T><A><D><T><M><R><S><L><R><E><M><G><M><D><S><A><I><R><E><V><I><A><R><G><T><P><F><L><G><I><C><V><G><M><Q><V><L><A><E><Q><S><E><E><F><G><L><H><E><C><L><G><L><V><P><G><T><I><R><R...
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.<BOP>
A9B5I2
Q82IC1
ISPT1_STRAW
Isoprenyl transferase 1
Streptomyces
<M><N><L><R><D><N><L><R><R><L><L><V><R><F><Y><A><R><R><V><E><G><H><L><D><H><D><Q><V><P><K><H><I><G><V><I><M><D><G><N><R><R><W><A><K><A><A><G><S><T><T><A><Q><G><H><R><A><G><A><D><K><I><E><E><F><L><G><W><C><S><E><T><D><V><G><V><V><T><L><W><L><L><S><T><D><N><F><D><R><P><Q><E><E><L><G><P><L><L><G><I><I><E><G><V><V><R><T><L...
Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.<BOP>
Q82IC1
Q8KER4
ILVD_CHLTE
Dihydroxy-acid dehydratase
Chlorobaculum
<M><R><S><D><T><I><K><K><G><F><E><K><A><P><H><R><S><L><L><K><A><T><G><C><V><S><T><R><D><D><F><S><K><P><F><I><G><I><C><N><S><F><N><E><L><I><P><G><H><A><H><L><Q><E><L><G><R><I><A><K><E><A><V><R><E><A><G><G><V><P><F><E><F><N><T><I><G><V><C><D><G><I><A><M><G><H><V><G><M><R><Y><S><L><A><S><R><E><L><I><A><D><S><V><E><T><V><V...
Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (...
Q8KER4
Q47XG4
GLYA3_COLP3
Serine hydroxymethyltransferase 3
Colwellia
<M><K><N><T><Y><T><S><G><E><L><E><Q><F><F><S><S><D><L><S><S><T><D><G><A><V><Q><V><A><I><D><L><E><E><A><R><Q><N><Q><Q><I><E><L><I><A><S><E><N><I><V><S><K><A><V><M><E><A><Q><G><T><V><L><T><N><K><Y><A><E><G><Y><P><G><R><R><Y><Y><G><G><C><E><H><V><D><L><V><E><T><L><A><I><D><R><A><K><L><I><F><K><A><D><F><V><N><V><Q><P><H><S...
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent a...
Q47XG4
A0AF20
COAX_LISW6
Pantothenic acid kinase
Listeria
<M><I><L><V><I><D><V><G><N><T><N><C><T><V><G><V><Y><E><K><Q><K><L><L><K><H><W><R><M><T><T><D><R><H><R><T><S><D><E><L><G><M><T><V><L><N><F><F><S><Y><A><N><L><T><P><S><D><I><Q><G><I><I><I><S><S><V><V><P><P><I><M><H><A><M><E><T><M><C><V><R><Y><F><N><I><R><P><L><I><V><G><P><G><I><K><T><G><L><N><V><K><V><D><N><P><R><E><I><G...
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.<BOP>
A0AF20
A4VZ21
DPO4_STRS2
DNA polymerase IV
Streptococcus
<M><L><I><F><P><L><I><N><D><L><S><R><K><I><I><H><V><D><M><D><A><F><F><A><A><I><E><V><R><D><S><P><A><L><K><G><K><P><V><I><I><G><A><D><P><R><L><S><G><G><R><G><V><V><S><T><C><N><Y><E><A><R><A><F><G><I><H><S><A><M><S><S><K><E><A><Y><E><R><C><P><Q><A><I><F><I><S><G><N><Y><E><K><Y><Q><E><V><G><R><Q><V><R><E><I><F><H><R><Y><T...
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in...
A4VZ21
Q45Z47
PA22_OXYSC
Phosphatidylcholine 2-acylhydrolase
Oxyuranus
<M><H><P><A><H><L><L><V><L><L><A><V><C><V><S><L><L><G><A><S><D><I><P><P><L><P><L><N><L><A><Q><F><G><F><M><I><R><C><A><N><G><G><S><R><S><P><L><D><Y><T><D><Y><G><C><Y><C><G><K><G><G><R><G><T><P><V><D><D><L><D><R><C><C><Q><V><H><D><E><C><Y><G><E><A><E><K><R><L><G><C><S><P><F><V><T><L><Y><S><W><K><C><Y><G><K><A><P><S><C><N...
Snake venom phospholipase A2 (PLA2) that shows high presynaptic neurotoxicity in vertebrata that is independent of catalytic activity , as well as local myotoxicity when intramuscularly injected into mice . Blocks acetylcholine release in Aplysia neurons , and potentiates pro-inflammatory cellular signaling . Potentiat...
Q45Z47