accession
stringlengths
6
10
name
stringlengths
6
11
Full Name
stringlengths
1
147
⌀
taxon
stringlengths
3
46
⌀
sequence
stringlengths
48
2.3k
function
stringlengths
11
1.34k
AlphaFoldDB
stringlengths
6
10
Q0E2P1
2ABB_ORYSJ
Serine/threonine protein phosphatase 2A 55 kDa regulatory subunit B beta isoform
Oryza sativa
<M><D><P><S><S><K><S><P><D><D><D><D><L><R><P><E><A><E><A><A><R><R><P><Q><P><Q><P><Q><P><R><E><W><R><F><A><Q><V><F><G><E><R><A><A><G><E><D><V><Q><E><V><D><I><I><S><A><I><E><F><D><K><S><G><D><H><L><A><T><G><D><R><G><G><R><V><V><L><F><E><R><T><D><S><R><D><S><A><S><R><S><E><L><E><R><Q><D><Y><P><I><A><R><H><P><E><F><R><Y><K...
The B regulatory subunit may modulate substrate selectivity and catalytic activity, and may also direct the localization of the catalytic enzyme to a particular subcellular compartment.<BOP>
Q0E2P1
Q82TU5
NUOC_NITEU
NDH-1 subunit C
Nitrosomonas
<M><T><N><S><R><L><E><K><L><A><A><D><L><Q><R><I><L><G><D><R><Q><I><D><I><S><C><A><L><G><E><L><T><L><L><V><H><S><R><D><L><P><D><I><A><E><V><L><R><D><H><Q><D><L><G><F><D><T><L><I><D><L><C><G><V><D><F><S><E><Y><S><T><D><T><H><A><G><Y><K><R><E><D><R><R><F><A><V><V><Y><H><L><L><S><V><K><H><N><H><R><L><R><V><R><V><F><A><E><D...
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are t...
Q82TU5
P12634
FLAD_CAUVC
Distal basal body ring component protein
Caulobacter
<M><K><A><F><L><F><A><A><A><A><T><L><V><I><T><A><L><S><A><P><A><F><A><G><T><P><V><T><L><R><M><D><T><T><D><A><D><G><R><I><T><L><G><D><L><F><D><G><V><S><G><P><A><A><N><V><V><V><A><A><R><M><S><A><T><A><V><L><E><A><G><Q><V><Q><M><S><A><R><R><A><G><Y><V><W><T><N><A><N><G><V><R><R><I><I><V><R><E><G><V><D><N><G><G><V><S><S><S...
FlaD might be the structural protein of the distal basal body ring P, or it is necessary for the assembly of the P ring.<BOP>
P12634
P82226
TK1B_HADVE
Kappa-hexatoxin-Hv1b
Hadronyche
<T><I><C><T><G><A><D><R><P><C><A><A><C><C><P><C><C><P><G><T><S><C><Q><G><P><E><P><N><G><V><S><Y><C><R><N><D>
This excitatory toxin inhibits insect calcium-activated potassium (KCa) channels (Slo-type).<BOP>
P82226
Q1GU79
ATP6_SPHAL
F-ATPase subunit 6
Sphingopyxis
<M><A><A><E><S><G><K><I><D><P><M><H><Q><F><E><V><T><P><L><G><G><G><F><N><L><G><G><Q><E><V><L><F><T><N><S><A><L><W><M><V><V><A><A><I><T><L><G><L><F><M><W><G><G><M><R><R><Q><L><V><P><G><R><W><Q><V><A><V><E><G><F><T><G><F><I><S><S><M><M><M><A><N><I><G><T><E><G><R><K><Y><T><P><Y><V><F><S><L><F><M><F><I><L><F><C><N><L><L><G...
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.<BOP>
Q1GU79
P86915
PSB_PSEBL
Pseudin-B
Pseudis
<G><L><N><T><L><K><K><V><I><Q><G><L><H><E><V><I><K><L><V><N><N><H><A>
Antimicrobial peptide with activity against both Gram-positive and Gram-negative bacteria . Has been tested against X.axonopodis pv. glycines (MIC<2 uM), E.coli ATCC 25922 (MIC=6 uM), S.aureus ATCC 29313 (MIC=6 uM) and P.aeruginosa ATCC 27853 (MIC=50 uM).<BOP>
P86915
P21742
THNB_HORVU
Acidic protein
Hordeum
<M><G><S><K><G><L><K><G><V><M><V><C><L><L><I><L><G><L><V><L><E><H><V><Q><V><E><G><K><S><C><C><R><S><T><L><G><R><N><C><Y><N><L><C><R><V><R><G><A><Q><K><L><C><A><N><A><C><R><C><K><L><T><S><G><L><K><C><P><S><S><F><P><K><L><A><L><V><S><N><S><D><E><P><D><T><I><D><Y><C><N><L><G><C><R><A><S><M><C><D><Y><M><V><N><A><A><A><D><D...
Thionins are small plant proteins which are toxic to animal cells. They seem to exert their toxic effect at the level of the cell membrane. Their precise function is not known.<BOP>
P21742
Q5NGX1
RLMD_FRATT
23S rRNA(m5U1939)-methyltransferase
Francisella
<M><G><R><S><R><H><H><N><K><L><K><E><G><I><F><E><A><E><I><T><A><L><S><H><D><G><R><G><I><A><K><V><D><G><K><T><T><F><I><P><F><T><L><P><G><E><V><V><K><F><E><Y><T><F><T><K><A><K><F><D><E><A><K><V><V><E><Y><V><K><K><S><S><N><R><V><N><P><P><C><D><H><F><Q><I><C><R><G><C><S><L><Q><H><M><S><T><D><A><Q><I><E><H><K><Q><Q><T><L><I...
Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.<BOP>
Q5NGX1
B2GCB7
LEUD_LIMF3
Isopropylmalate isomerase
Limosilactobacillus
<M><D><K><F><T><V><H><T><G><T><T><L><A><I><M><N><D><N><I><D><T><D><Q><L><L><P><K><Q><F><L><K><R><L><T><K><K><G><Y><E><D><A><L><F><F><E><W><R><Y><K><E><D><G><S><N><N><P><D><F><I><L><N><D><P><E><R><Q><D><A><S><I><L><I><T><G><D><S><F><G><I><G><S><S><R><E><H><A><V><W><A><L><R><D><W><G><F><K><A><V><I><A><G><S><F><G><P><I><L...
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.<BOP>
B2GCB7
B1XJ08
YQGF_SYNP2
Putative pre-16S rRNA nuclease
unclassified Synechococcus
<M><K><P><V><A><A><L><G><L><D><I><G><R><K><R><I><G><V><A><G><C><D><G><L><G><L><L><A><T><A><L><T><T><I><Q><R><T><T><L><E><A><D><L><A><A><I><A><H><W><I><E><Q><R><H><I><Q><V><L><V><V><G><L><P><Y><A><M><D><G><S><L><G><K><Q><A><K><Q><T><Q><K><F><A><R><K><L><A><E><A><F><G><L><P><I><E><Y><V><D><E><R><L><T><S><V><E><A><E><N><Q...
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.<BOP>
B1XJ08
Q1GTY6
PYRG_SPHAL
UTP--ammonia ligase
Sphingopyxis
<M><A><R><F><I><F><I><T><G><G><V><V><S><S><L><G><K><G><L><M><A><A><S><L><A><A><L><L><Q><A><R><G><Y><R><V><R><I><R><K><F><D><P><Y><L><N><V><D><P><G><T><M><S><P><Y><Q><H><G><E><V><Y><V><T><D><D><G><A><E><T><D><L><D><L><G><H><Y><E><R><F><T><G><V><A><A><R><Q><S><D><N><V><T><S><G><R><I><Y><Q><G><I><I><A><K><E><R><R><G><D><Y...
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.<BOP>
Q1GTY6
B3EJ63
ARGR_CHLPB
Arginine repressor
Chlorobium
<M><S><K><Q><I><R><H><R><K><I><K><E><I><L><L><S><S><T><V><T><N><Q><H><E><L><I><L><L><L><E><K><R><G><I><D><V><A><Q><A><T><L><S><R><D><C><S><E><L><G><V><L><R><S><R><T><A><S><G><Y><R><L><M><I><P><E><D><N><P><G><Q><M><I><K><G><L><V><E><M><E><I><Q><S><I><E><S><N><E><S><S><I><V><I><K><T><L><P><G><R><A><H><G><V><G><S><F><I><D...
Regulates arginine biosynthesis genes.<BOP>
B3EJ63
A7Z7A9
ENGB_BACVZ
Probable GTP-binding protein EngB
Bacillus amyloliquefaciens group
<M><K><V><T><K><S><E><I><V><I><S><A><V><K><P><E><Q><Y><P><D><G><G><L><P><E><I><A><L><A><G><R><S><N><V><G><K><S><S><F><I><N><S><L><I><N><R><K><N><L><A><R><T><S><S><K><P><G><K><T><Q><T><L><N><F><Y><I><I><N><D><E><L><H><F><V><D><V><P><G><Y><G><F><A><K><V><S><K><S><E><R><E><A><W><G><R><M><I><E><T><Y><M><T><T><R><E><E><L><K...
Necessary for normal cell division and for the maintenance of normal septation.<BOP>
A7Z7A9
P01588
EPO_HUMAN
Erythropoietin
Homo
<M><G><V><H><E><C><P><A><W><L><W><L><L><L><S><L><L><S><L><P><L><G><L><P><V><L><G><A><P><P><R><L><I><C><D><S><R><V><L><E><R><Y><L><L><E><A><K><E><A><E><N><I><T><T><G><C><A><E><H><C><S><L><N><E><N><I><T><V><P><D><T><K><V><N><F><Y><A><W><K><R><M><E><V><G><Q><Q><A><V><E><V><W><Q><G><L><A><L><L><S><E><A><V><L><R><G><Q><A><L...
Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3.<BOP>
P01588
A7I1G2
TPIS_CAMHC
Triose-phosphate isomerase
Campylobacter
<M><I><V><A><A><N><L><K><C><N><H><T><R><A><S><F><L><N><F><T><K><K><L><D><N><F><L><S><G><E><A><S><N><F><K><K><N><E><I><L><I><F><P><P><N><T><A><F><C><D><Q><I><S><N><F><T><Q><G><A><Q><N><F><F><P><C><E><N><G><S><F><T><G><E><I><G><A><D><M><L><N><E><F><G><I><K><S><V><L><I><G><H><S><E><R><R><V><I><F><S><E><S><D><R><M><V><L><E...
Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).<BOP>
A7I1G2
P0C2M8
YSCB_YEREN
null
Yersinia
<M><Q><N><L><L><K><N><L><A><T><S><L><G><R><K><P><F><V><A><D><K><Q><G><V><Y><R><L><T><I><D><K><H><L><V><M><L><T><P><H><G><S><E><L><V><L><R><T><P><I><D><A><P><M><L><R><E><G><N><N><V><N><V><T><L><L><R><S><L><M><Q><Q><A><L><A><W><A><K><R><Y><P><Q><T><L><V><L><D><D><C><G><Q><L><V><L><E><A><R><L><R><L><Q><E><L><D><T><H><G><L...
Functions as a specific chaperone for YopN. It could facilitate the secretion and the subsequent translocation of YopN.<BOP>
P0C2M8
B2S9R7
AROC_BRUA1
5-enolpyruvylshikimate-3-phosphate phospholyase
Brucella
<M><S><H><N><S><F><G><H><L><F><R><V><T><T><W><G><E><S><H><G><L><A><L><G><C><V><V><D><G><C><P><P><G><I><T><F><T><E><A><E><I><Q><S><F><L><D><K><R><K><P><G><Q><S><K><Y><T><T><Q><R><R><E><P><D><Q><V><R><V><L><S><G><V><L><L><G><E><D><G><V><T><M><T><T><T><G><T><P><I><S><M><M><I><E><N><T><D><Q><R><S><K><D><Y><G><E><I><A><R><Q...
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a s...
B2S9R7
P49882
ECR_CHITE
Nuclear receptor subfamily 1 group H member 1
Chironomus
<M><K><T><E><N><L><I><V><T><T><V><K><V><E><P><L><N><Y><A><S><Q><S><F><G><D><N><N><I><Y><G><G><A><T><K><K><Q><R><L><E><S><D><E><W><M><N><H><N><Q><T><N><M><N><L><E><S><S><N><M><N><H><N><T><I><S><G><F><S><S><P><D><V><N><Y><E><A><Y><S><P><N><S><K><L><D><D><G><N><M><S><V><H><M><G><D><G><L><D><G><K><K><S><S><S><K><K><G><P><V...
Receptor for ecdysone. Binds to ecdysone response elements (ECRES).<BOP>
P49882
Q9PE75
RL4_XYLFA
50S ribosomal protein L4
Xylella
<M><D><L><T><I><V><G><S><D><N><T><L><P><V><S><D><V><V><F><G><R><E><F><S><E><A><L><V><H><Q><I><V><V><A><Y><R><N><T><A><R><S><G><T><K><A><Q><K><S><R><S><Q><V><S><G><T><T><K><K><S><K><K><Q><K><G><G><G><A><R><H><G><A><L><T><A><P><I><F><V><G><G><G><V><A><F><A><A><K><P><R><S><F><S><Q><K><V><N><R><K><Q><Y><R><S><A><I><C><S><I...
Forms part of the polypeptide exit tunnel.<BOP>
Q9PE75
B5FKW1
COF_SALDC
HMP-PP phosphatase
Salmonella
<M><A><R><L><A><A><F><D><M><D><G><T><L><L><M><P><D><H><H><L><G><R><E><T><I><A><T><L><A><R><L><R><E><R><D><I><T><L><T><F><A><T><G><R><H><V><L><E><M><R><H><I><L><G><T><L><S><L><D><A><Y><L><I><T><G><N><G><T><R><I><H><S><L><E><G><D><V><L><H><R><Q><D><L><D><P><Q><V><A><D><T><V><M><H><H><A><W><D><T><R><A><S><M><H><V><F><N><D...
Catalyzes the hydrolysis of 4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2-methyl-5-hydroxymethylpyrimidine phosphate (HMP-P).<BOP>
B5FKW1
A0A059WLZ7
CNDA_RHIWD
Three-component Rieske non-heme iron oxygenase system
Rhizorhabdus
<M><F><L><Q><N><A><W><Y><A><V><A><W><C><D><E><V><T><D><G><I><V><T><R><K><V><L><G><R><E><L><A><L><F><R><D><G><E><G><Q><P><R><A><I><L><N><R><C><P><H><R><F><A><P><L><S><L><G><K><R><I><G><D><A><I><Q><C><P><Y><H><G><L><H><F><G><P><D><G><R><C><V><H><N><P><H><G><D><G><V><V><P><D><V><A><T><P><T><F><P><A><R><E><R><H><K><L><I><W...
Component of the chloroacetanilide N-alkylformylase multicomponent enzyme system involved in the degradation of chloroacetanilide herbicides (N-alkoxyalkyl-N-chloroacetyl-substituted aniline derivatives). In vitro, catalyzes the N-dealkylation of butachlor, alachlor and acetochlor to yield 2-chloro-N-(2,6-diethylphenyl...
A0A059WLZ7
Q47085
CBRB_DICD3
Achromobactin transport system permease protein CbrB
Dickeya
<M><S><H><A><V><I><P><T><G><R><R><I><A><P><G><Q><V><L><A><G><G><G><V><C><L><L><A><L><A><V><L><S><L><M><V><G><P><V><W><I><A><P><S><Q><V><L><G><A><L><W><H><P><D><P><L><N><V><S><H><I><L><V><T><S><T><R><L><S><R><T><L><I><A><I><V><V><G><A><G><L><A><V><A><G><A><L><M><Q><V><L><T><R><N><P><L><A><S><P><G><L><F><G><I><N><A><G><A...
Part of the binding-protein-dependent transport system CbrABCD for uptake of the siderophore achromobactin. Probably responsible for the translocation of the substrate across the membrane.<BOP>
Q47085
Q6E3K9
PRONF_PROFF
Propionicin-F
Propionibacterium
<M><N><T><K><A><V><N><L><K><S><E><N><T><T><K><L><V><S><Y><L><T><E><N><Q><L><D><E><F><I><R><R><I><R><I><D><G><A><L><V><E><E><V><S><Q><N><A><K><Q><A><L><D><N><T><G><L><N><G><W><I><N><T><D><C><D><E><G><L><L><S><D><F><I><S><K><I><A><S><A><R><W><I><P><L><A><E><S><I><R><P><A><V><T><D><R><D><K><Y><R><V><S><C><W><F><Y><Q><G><M...
Bacteriocin with specific antibacterial activity against strains of P.freudenreichii. No antibacterial activity was detected against P.acidipropionici, P.jensenii and P.thoenii.<BOP>
Q6E3K9
B0VT23
PDXB_ACIBS
Erythronate-4-phosphate dehydrogenase
Acinetobacter calcoaceticus/baumannii complex
<M><K><I><V><A><D><E><N><L><A><F><T><D><Y><F><F><S><E><F><G><D><I><Q><H><K><A><G><R><T><L><T><H><T><D><V><Q><D><A><E><A><L><L><V><R><S><V><T><A><V><N><E><S><L><I><Q><N><T><A><L><K><Y><V><G><S><A><T><I><G><T><D><H><L><D><I><Q><A><L><E><K><Q><G><I><T><W><A><N><A><A><G><C><N><A><Q><A><V><A><E><Y><V><I><T><A><L><L><H><L><D...
Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.<BOP>
B0VT23
A5WBV9
ATPA_PSYWF
F-ATPase subunit alpha
Psychrobacter
<M><Q><Q><L><N><P><A><E><I><S><Q><L><I><K><Q><R><I><Q><D><L><D><T><S><A><T><A><K><N><E><G><T><I><V><K><V><S><D><G><I><V><Q><I><H><G><L><E><D><A><M><Y><G><E><M><I><E><F><E><G><D><V><Y><G><M><A><L><N><L><E><Q><D><S><V><G><A><V><V><L><G><D><Y><L><G><L><Q><E><G><Q><K><A><Y><C><T><G><R><I><L><E><V><P><V><G><P><E><L><L><G><R...
Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.<BOP>
A5WBV9
P18165
LORI_MOUSE
Loricrin
Mus
<M><S><H><Q><K><K><Q><P><T><P><C><P><P><V><G><C><G><K><T><S><G><G><G><G><G><G><G><G><G><G><G><G><G><Y><Y><S><G><G><G><S><G><C><G><G><G><S><S><G><G><G><S><S><C><G><G><G><G><G><G><S><Y><G><G><G><S><S><C><G><G><G><G><G><S><G><G><G><V><K><Y><S><G><G><G><G><G><S><S><C><G><G><G><Y><S><G><G><G><G><G><S><S><C><G><G><G><Y><S><G...
Major keratinocyte cell envelope protein.<BOP>
P18165
B2HHY2
OTSA_MYCMM
Osmoregulatory trehalose synthesis protein A
Mycobacterium
<M><G><P><G><G><R><Q><S><A><E><P><A><S><T><E><V><F><G><D><S><D><F><V><V><V><A><N><R><L><P><V><D><Q><E><R><L><P><D><G><T><I><A><W><K><R><S><P><G><G><L><V><T><A><L><E><P><L><L><R><R><R><R><G><A><W><V><G><W><A><G><V><V><E><N><D><V><D><V><Q><D><E><P><I><V><Q><D><E><L><Q><L><Q><P><V><R><L><S><A><D><D><V><A><Q><Y><Y><E><G><F...
Probably involved in the osmoprotection via the biosynthesis of trehalose and in the production of glycogen and alpha-glucan via the TreS-Pep2 branch involved in the biosynthesis of maltose-1-phosphate (M1P). Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalo...
B2HHY2
Q9PK40
RSMA_CHLMU
S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase
Chlamydia
<M><A><R><S><S><I><E><Q><L><T><S><F><L><K><S><V><N><G><R><A><K><K><A><L><S><Q><N><F><L><V><D><G><N><I><L><R><K><I><L><A><T><A><D><V><Q><P><G><D><W><V><L><E><I><G><P><G><F><G><A><L><S><E><V><L><V><S><Q><G><A><N><V><I><A><L><E><K><D><P><M><F><E><E><S><L><S><Q><L><P><I><D><I><E><I><T><D><A><C><K><Y><P><L><A><S><L><D><D><K...
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.<BOP>
Q9PK40
A8Z689
RS11_SULMW
30S ribosomal protein S11
Candidatus Sulcia
<M><E><K><T><F><T><F><R><K><K><N><S><R><N><Y><N><I><G><E><A><H><I><K><S><T><Y><N><N><I><I><I><T><L><T><N><K><K><G><D><V><I><A><W><S><S><A><G><K><M><G><F><K><G><S><K><K><N><T><P><Y><A><A><Q><I><T><A><E><D><V><A><E><K><G><L><N><A><G><I><K><K><L><K><V><I><V><K><G><P><G><A><G><R><D><A><A><I><R><A><L><V><N><K><N><L><I><L><L...
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.<BOP>
A8Z689
D3F5L6
FBID_CONWI
Phosphoenolpyruvate guanylyltransferase
Conexibacter
<M><S><T><F><A><I><L><P><V><K><R><F><E><G><A><K><G><R><L><A><G><G><L><A><A><G><P><R><R><A><L><A><E><A><M><Y><V><D><V><L><T><A><L><R><R><T><Q><G><V><D><R><V><L><V><L><T><A><D><P><G><A><Q><R><V><A><E><G><Y><D><A><I><P><L><D><D><P><A><E><A><G><Q><N><R><A><V><M><R><G><V><A><H><A><R><E><L><G><A><T><R><V><L><C><L><S><G><D><T...
Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.<BOP>
D3F5L6
Q47KT3
ISPF_THEFY
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Thermobifida
<M><V><G><V><G><T><D><V><H><P><F><Q><T><G><R><P><L><F><L><A><G><L><E><W><P><D><E><V><G><L><S><G><H><S><D><G><D><V><A><A><H><A><A><C><D><A><L><F><S><A><C><A><L><G><D><L><G><S><Q><F><G><T><S><D><P><R><W><R><G><A><S><G><V><A><L><L><T><E><A><A><Q><R><V><R><A><A><G><Y><E><I><G><N><I><A><I><Q><I><I><G><N><R><P><K><F><A><P><R...
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a correspond...
Q47KT3
Q9F1W4
HRCA_PARTM
Heat-inducible transcription repressor HrcA
Parageobacillus
<M><L><T><D><R><Q><L><L><I><L><Q><V><I><I><D><D><F><I><R><S><G><Q><P><V><G><S><R><A><L><S><K><K><H><E><I><S><L><S><S><A><T><I><R><N><E><M><A><D><L><E><E><L><G><Y><I><E><K><T><H><A><S><S><G><R><V><P><S><E><K><G><Y><R><Y><Y><V><D><H><L><L><S><P><Q><R><L><T><Q><E><D><I><Q><K><I><K><S><I><F><A><E><R><I><Y><D><L><E><K><V><V...
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.<BOP>
Q9F1W4
Q0AUK4
IF1_SYNWW
Translation initiation factor IF-1
Syntrophomonas
<M><A><K><E><D><V><I><E><V><E><G><T><V><V><E><P><L><P><N><T><M><F><K><V><E><L><D><N><G><H><K><V><L><A><H><I><S><G><K><M><R><M><N><F><V><R><I><L><P><G><D><R><V><M><V><E><L><S><P><Y><D><L><N><R><G><R><I><I><Y><R><F><K>
One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-...
Q0AUK4
A8GT00
RNPA_RICRS
Protein C5
spotted fever group
<M><S><I><T><S><L><K><N><Q><K><E><F><E><L><I><N><K><L><G><K><K><L><H><E><R><Y><F><I><L><V><I><A><T><K><L><P><K><I><F><L><E><S><K><Y><N><T><F><L><G><I><K><V><S><R><K><L><N><K><K><A><V><V><R><N><K><I><K><R><R><I><R><H><L><I><R><I><I><V><S><D><S><S><F><K><D><I><K><F><A><M><I><I><I><P><R><K><G><F><E><E><I><N><F><S><H><L><N...
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the riboz...
A8GT00
Q8R2R3
AAGAB_MOUSE
Alpha- and gamma-adaptin-binding protein p34
Mus
<M><A><A><G><V><P><C><A><L><V><T><S><C><S><A><T><F><T><G><D><R><L><V><Q><H><I><L><G><T><E><D><A><V><V><E><A><T><S><S><D><A><V><R><F><Y><P><W><T><I><D><N><K><Y><Y><S><A><E><I><N><L><C><V><V><P><S><K><F><L><V><T><A><E><I><A><E><S><V><Q><A><F><V><V><Y><F><D><S><T><Q><K><S><G><L><D><S><V><S><S><W><L><P><L><A><E><A><W><L><A...
May be involved in endocytic recycling of growth factor receptors such as EGFR.<BOP>
Q8R2R3
Q70Z18
NAP1B_TOBAC
Nucleosome assembly protein 1-like 2
Nicotiana
<M><S><N><T><K><D><N><F><N><V><A><D><L><T><A><A><L><N><A><G><D><R><A><D><L><V><N><V><L><K><N><K><L><H><D><L><T><G><K><H><S><N><V><T><E><S><L><S><P><N><V><R><K><R><V><E><A><L><R><E><I><Q><T><E><H><D><E><L><E><A><K><F><F><E><E><R><A><A><L><E><A><K><Y><Q><K><L><Y><Q><P><L><Y><T><K><R><F><E><I><V><N><G><V><V><E><V><D><G><A...
May modulate chromatin structure by regulation of nucleosome assembly/disassembly. Could function together with B-type cyclins in the regulation of microtubule dynamics.<BOP>
Q70Z18
Q10409
TSR3_SCHPO
18S rRNA aminocarboxypropyltransferase
Schizosaccharomyces
<M><G><P><R><S><S><N><R><R><S><N><A><K><D><G><F><K><G><S><N><K><A><S><K><F><P><L><P><L><A><M><W><D><F><G><H><C><N><P><N><A><C><S><G><K><R><L><E><R><L><G><C><V><R><N><L><R><I><G><Q><K><F><R><G><V><V><I><T><P><N><G><K><V><P><V><S><P><A><D><K><E><Y><F><D><N><G><G><A><S><V><V><E><C><S><W><A><R><I><E><E><I><P><F><S><R><I><G...
Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine at position 1191 (Psi1191) in 18S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA. Required for process...
Q10409
A0Q6E3
TTCA1_FRATN
tRNA 2-thiocytidine biosynthesis protein TtcA 1
Francisella
<M><T><N><N><T><D><K><Q><T><L><K><K><L><E><R><Q><I><L><R><K><T><A><Q><A><I><N><Q><Y><N><M><I><E><D><G><D><K><I><M><V><C><L><S><G><G><K><D><S><Y><C><L><L><E><M><L><L><L><L><Q><K><K><A><P><I><S><F><E><I><I><A><V><N><L><D><Q><K><Q><P><G><F><P><E><E><V><L><P><N><Y><L><K><N><K><G><V><E><F><H><I><I><Q><R><D><T><Y><S><V><V><K...
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.<BOP>
A0Q6E3
Q8GWA2
MOC1_ARATH
Protein MONOKARYOTIC CHLOROPLAST 1
Arabidopsis
<M><A><T><T><V><Y><G><Q><A><S><L><P><Q><M><H><S><L><F><S><K><V><R><P><F><L><S><H><S><P><S><F><T><A><P><F><T><R><R><R><S><F><P><F><S><A><L><P><T><T><K><A><I><D><A><A><L><M><K><E><K><W><L><D><S><L><S><L><T><S><Q><D><E><D><T><T><P><E><N><A><E><S><S><C><I><I><G><I><D><P><D><L><S><G><A><L><A><L><L><K><F><D><H><L><G><S><S><S...
A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products. Mediates chlorop...
Q8GWA2
P0DC00
KPRS2_STRP3
Phosphoribosyl pyrophosphate synthase 2
Streptococcus
<M><T><E><R><Y><A><D><K><Q><I><K><L><F><S><L><T><S><N><L><P><I><A><E><K><I><A><K><A><A><G><I><P><L><G><K><M><S><S><R><Q><F><S><D><G><E><I><M><I><N><I><E><E><T><V><R><G><D><D><I><Y><I><I><Q><S><T><S><F><P><V><N><D><N><L><W><E><L><L><I><M><I><D><A><C><Q><R><A><S><A><N><T><V><N><I><V><L><P><Y><F><G><Y><S><R><Q><D><R><V><A...
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).<BOP>
P0DC00
P46050
FER3_TRIV2
Ferredoxin III
Trichormus
<M><A><T><L><T><G><L><T><F><G><G><Q><V><W><T><P><Q><F><V><E><A><V><N><Q><D><K><C><I><G><C><G><R><C><F><K><A><C><G><R><N><V><L><I><L><Q><A><L><N><E><N><G><E><F><V><E><D><E><E><G><E><E><I><E><R><K><V><M><S><I><I><H><P><E><Y><C><I><G><C><Q><A><C><A><R><A><C><P><K><N><C><Y><T><H><S><P><L><E><H><N>
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.<BOP>
P46050
Q7UVL4
ARGC_RHOBA
N-acetyl-glutamate semialdehyde dehydrogenase
Rhodopirellula
<M><S><S><S><N><L><R><V><A><L><V><G><S><T><G><Y><T><A><L><E><V><A><R><L><L><L><T><H><P><G><A><D><L><V><V><A><T><S><R><Q><D><E><G><K><P><L><S><E><I><H><P><M><L><A><G><R><C><D><V><T><L><Q><P><L><D><A><D><V><I><A><K><S><A><D><V><A><M><C><C><L><P><H><G><A><S><A><E><S><V><K><Q><L><A><E><A><G><M><R><V><I><D><F><S><A><D><F><R...
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.<BOP>
Q7UVL4
Q724H7
ISPD_LISMF
MEP cytidylyltransferase
Listeria
<M><N><Y><E><L><V><F><L><A><A><G><Q><G><K><R><M><N><A><Q><K><N><K><M><W><L><E><L><V><G><E><P><I><F><I><H><A><L><R><P><F><L><A><D><N><R><C><S><K><V><I><V><V><S><Q><E><E><E><R><K><H><V><K><E><L><M><S><Q><L><N><V><A><E><S><R><I><E><I><V><K><G><G><S><E><R><Q><Y><S><V><A><A><G><L><E><R><C><G><T><E><R><V><V><L><V><H><D><G><A...
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).<BOP>
Q724H7
Q8NRI0
NADA_CORGL
Quinolinate synthase
Corynebacterium
<M><P><D><V><Y><G><P><G><A><S><Q><N><D><P><I><P><A><H><A><P><R><Q><Q><V><L><P><E><E><Y><Q><R><A><S><D><D><E><L><H><R><R><I><R><E><A><K><D><T><L><G><D><K><V><V><I><L><G><H><F><Y><Q><R><D><E><V><I><Q><H><A><D><F><V><G><D><S><F><Q><L><A><R><A><A><K><T><R><P><E><A><E><A><I><V><F><C><G><V><H><F><M><A><E><T><A><D><L><L><S><T...
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.<BOP>
Q8NRI0
Q93V66
FAX1_ARATH
Protein FATTY ACID EXPORT 1, chloroplastic
Arabidopsis
<M><A><S><Q><I><S><Q><L><A><C><F><S><S><T><N><R><Q><F><H><F><Q><S><R><S><F><P><C><P><M><I><R><P><Q><S><F><V><V><K><S><V><D><G><N><S><S><E><T><P><A><S><L><S><Y><T><A><E><V><S><K><P><V><V><E><K><T><S><K><P><Y><S><T><V><D><E><T><A><T><N><K><E><S><I><T><E><P><V><E><E><D><V><A><T><Q><P><I><R><A><A><K><I><H><D><F><C><F><G><I...
Mediates the export of free fatty acid from the plastids. Potentially prefers palmitic acid (C16:0) over oleic acid (C18:1) and stearic acid (C18:0). Not involved in fatty acid activation. Required for biogenesis of the outer pollen cell wall, in particular for the assembly of exine and pollen coat and for the release ...
Q93V66
Q5HZE0
MCATL_RAT
Solute carrier family 25 member 29
Rattus
<M><A><L><D><F><L><A><G><C><A><G><G><V><A><G><V><I><V><G><H><P><F><D><T><V><K><V><R><L><Q><V><Q><N><T><E><K><P><Q><Y><R><G><T><L><H><C><F><Q><S><I><I><K><Q><E><S><V><L><G><L><Y><K><G><L><G><S><P><L><M><G><L><T><F><I><N><A><L><V><F><G><V><Q><G><N><T><L><R><A><L><G><Q><D><S><P><L><N><Q><F><L><A><G><A><A><A><G><A><I><Q><C...
Transports arginine, lysine, homoarginine, methylarginine and, to a much lesser extent, ornithine and histidine. Can restore ornithine transport in cells lacking the primary mitochondrial ornithine transporter SLC25A15. Does not transport carnitine nor acylcarnitines. Functions by both counter-exchange and uniport mech...
Q5HZE0
Q6MNQ3
RNY1_BDEBA
Ribonuclease Y 1
Bdellovibrio
<M><E><I><V><I><S><A><I><I><G><L><L><I><G><G><T><V><V><F><V><I><K><R><L><Q><D><N><N><K><K><K><S><A><R><F><E><A><E><R><I><V><N><K><A><N><S><E><A><A><K><I><K><K><E><S><E><N><K><A><K><D><F><E><S><R><A><R><K><N><V><E><Q><D><I><H><K><Q><K><S><T><L><K><N><K><E><S><Q><L><E><R><R><L><K><E><V><E><D><Q><F><K><Q><K><M><E><E><N><E...
Endoribonuclease that initiates mRNA decay.<BOP>
Q6MNQ3
B9DJN5
MURB_STACT
UDP-N-acetylmuramate dehydrogenase
Staphylococcus
<M><H><K><D><D><I><L><K><E><L><K><K><V><L><P><E><E><I><I><K><V><D><E><P><L><K><R><Y><T><Y><T><Q><T><G><G><N><A><D><F><Y><L><S><P><T><T><N><E><Q><V><Q><A><I><N><H><L><A><R><M><N><N><I><P><V><T><Y><L><G><N><G><S><N><I><I><I><R><E><G><G><I><R><G><I><V><L><S><L><L><S><M><D><Y><I><K><V><E><D><N><V><I><I><A><G><S><G><A><A><I...
Cell wall formation.<BOP>
B9DJN5
A0QUB2
SECBL_MYCS2
SecB-like chaperone SmegB
Mycolicibacterium
<M><I><E><R><D><G><A><P><T><F><E><D><V><Q><E><L><L><N><R><S><E><L><T><D><V><A><L><Y><E><H><A><G><R><R><V><D><D><A><V><D><D><E><F><S><L><Q><V><L><T><R><V><G><D><T><E><F><E><I><R><C><K><V><T><A><A><G><H><G><G><Q><Y><L><A><D><A><G><A><V><F><T><L><Q><S><A><A><K><I><E><E><G><T><A><R><E><F><A><E><K><V><G><V><M><A><V><Y><P><Y...
Chaperone component of an orphan antitoxin chaperone (AC) system; there is no toxin gene in close genomic proximity. When expressed in E.coli complements the cold-sensitive phenotype of a secB deletion, suggesting it may have a generic chaperone function. Does not however complement the toxin-neutralizing effect of its...
A0QUB2
Q6FZL8
RL7_BARQU
50S ribosomal protein L7/L12
Bartonella
<M><A><D><L><A><K><I><V><E><D><L><S><N><L><T><L><L><E><A><A><E><L><S><K><L><L><E><E><K><W><G><V><S><A><A><A><P><V><A><V><A><T><V><A><G><A><A><A><P><A><A><E><E><K><T><E><F><D><V><I><L><V><D><C><G><A><Q><K><I><N><V><I><K><E><V><R><A><L><T><G><L><G><L><K><E><A><K><D><L><V><E><G><A><P><K><P><I><K><E><G><A><S><K><D><E><A><E...
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.<BOP>
Q6FZL8
P33434
MMP2_MOUSE
PEX
Mus
<M><E><A><R><V><A><W><G><A><L><A><G><P><L><R><V><L><C><V><L><C><C><L><L><G><R><A><I><A><A><P><S><P><I><I><K><F><P><G><D><V><A><P><K><T><D><K><E><L><A><V><Q><Y><L><N><T><F><Y><G><C><P><K><E><S><C><N><L><F><V><L><K><D><T><L><K><K><M><Q><K><F><F><G><L><P><Q><T><G><D><L><D><Q><N><T><I><E><T><M><R><K><P><R><C><G><N><P><D><V...
Mediates the proteolysis of CHUK/IKKA and initiates a primary innate immune response by inducing mitochondrial-nuclear stress signaling with activation of the pro-inflammatory NF-kappaB, NFAT and IRF transcriptional pathways.<BOP>
P33434
L0E1U3
METAS_THIND
Homoserine transsuccinylase
Thioalkalivibrio
<M><P><L><V><A><H><S><N><L><P><T><F><E><R><L><R><K><E><G><G><T><V><L><P><N><D><Y><A><L><H><Q><D><I><R><A><L><H><I><G><L><L><N><M><M><P><D><A><A><L><A><A><T><E><R><Q><F><F><R><L><V><G><E><S><N><Q><I><A><Q><F><Y><M><H><P><F><T><L><A><E><L><P><R><G><P><G><G><Q><A><H><V><E><R><Y><Y><E><T><F><D><T><I><Q><R><E><G><L><D><A><L...
Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.<BOP>
L0E1U3
Q61168
LAPM5_MOUSE
Retinoic acid-inducible E3 protein
Mus
<M><A><S><R><A><A><P><V><R><Q><T><C><C><C><F><N><I><R><V><A><T><I><A><L><A><I><Y><H><I><V><M><S><V><L><L><F><I><E><H><V><V><E><V><A><R><G><K><V><S><C><R><F><F><K><M><P><Y><L><R><M><A><D><L><L><S><S><F><L><L><I><G><V><L><F><I><I><S><I><S><L><L><F><G><V><V><K><N><R><E><K><Y><L><I><P><F><L><S><L><Q><I><M><D><F><L><L><C><L...
May have a special functional role during embryogenesis and in adult hematopoietic cells.<BOP>
Q61168
B3PDE5
CE2B_CELJU
CjCE2B
Cellvibrio
<M><K><P><H><A><L><I><G><L><L><A><G><M><L><L><S><S><S><L><Y><A><A><D><S><T><K><P><L><P><L><H><I><G><G><R><V><L><V><E><S><P><A><N><Q><P><V><S><Y><T><Y><S><W><P><A><V><Y><F><E><T><A><F><K><G><Q><S><L><T><L><K><F><D><D><D><Q><N><I><F><R><L><I><V><D><D><K><A><P><V><V><I><N><K><P><G><K><V><D><Y><P><V><E><S><L><A><P><G><K><H...
Involved in the degradation of plant cell wall polysaccharides. Catalyzes the deacetylation of acetylated birchwood xylan and glucomannan, with a large preference for the latter, and of the synthetic substrate 4-nitrophenyl acetate (4-NPAc).<BOP>
B3PDE5
B7IYE9
RECO_BACC2
Recombination protein O
Bacillus cereus group
<M><F><Q><K><V><E><G><I><V><I><R><T><T><D><Y><G><E><T><N><K><I><V><T><I><F><S><R><E><L><G><K><I><S><A><M><A><R><G><A><K><K><P><K><S><R><L><A><S><V><S><Q><L><M><T><H><G><H><F><L><I><Q><M><G><S><G><L><G><T><L><Q><Q><G><E><I><I><S><T><M><K><E><I><R><E><D><I><F><L><T><A><Y><A><S><F><I><V><E><L><T><D><K><A><T><E><D><K><K><H...
Involved in DNA repair and RecF pathway recombination.<BOP>
B7IYE9
O77689
CCNB2_BOVIN
G2/mitotic-specific cyclin-B2
Bos
<M><A><L><L><R><R><P><T><V><S><T><D><L><E><N><N><D><T><G><V><N><S><K><P><K><S><H><V><T><I><R><R><A><V><L><E><E><I><G><N><R><V><T><T><R><A><I><Q><V><A><K><K><A><Q><N><T><K><V><P><V><P><P><T><K><T><T><N><V><N><K><H><P><K><P><T><A><S><V><K><P><V><Q><M><D><V><L><A><P><K><G><P><S><P><T><P><Q><D><I><S><M><K><E><E><N><L><C><Q...
Essential for the control of the cell cycle at the G2/M (mitosis) transition.<BOP>
O77689
Q3A6N2
RL6_SYNC1
50S ribosomal protein L6
Syntrophotalea
<M><S><R><I><G><K><K><P><I><D><I><P><K><G><V><T><V><S><L><A><G><D><T><V><T><V><K><G><P><K><G><E><L><T><R><N><I><V><A><G><I><R><L><E><T><A><G><D><Q><I><L><V><Q><C><E><K><E><G><K><Q><E><G><A><Y><R><G><L><V><R><A><L><V><A><N><M><V><E><G><V><T><N><G><F><E><R><V><L><E><I><N><G><V><G><Y><R><A><E><V><K><G><S><A><L><N><L><S><L...
This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.<BOP>
Q3A6N2
Q0TG16
MDTA_ECOL5
Multidrug transporter MdtA
Escherichia
<M><K><G><S><Y><K><S><R><W><V><I><V><I><V><V><V><I><A><A><I><A><A><F><W><F><W><Q><G><R><N><D><S><Q><S><A><A><P><G><A><T><K><Q><A><Q><Q><S><P><A><G><G><R><R><G><M><R><A><G><P><L><A><P><V><Q><A><A><T><A><V><E><Q><A><V><P><R><Y><L><T><G><L><G><T><I><T><A><A><N><T><V><T><V><R><S><R><V><D><G><Q><L><M><A><L><H><F><Q><E><G><Q...
The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate.<BOP>
Q0TG16
Q7WCW3
ISPD_BORBR
MEP cytidylyltransferase
Bordetella
<M><S><E><S><L><I><A><I><V><P><A><A><G><I><G><A><R><A><S><L><P><G><E><A><A><V><P><K><Q><Y><R><P><L><A><G><Q><P><M><L><R><H><A><V><R><A><L><L><A><D><P><R><I><V><Q><V><R><V><A><V><S><A><G><D><G><W><V><E><Q><A><L><A><G><L><P><R><T><V><W><R><P><C><G><G><P><N><R><A><D><T><V><A><A><A><L><A><D><S><G><A><A><A><D><D><W><I><L><V...
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).<BOP>
Q7WCW3
B1J1W0
DAPF_PSEPW
PLP-independent amino acid racemase
Pseudomonas
<M><L><L><R><F><T><K><M><H><G><L><G><N><D><F><M><V><L><D><L><V><S><Q><H><A><H><I><Q><P><K><H><A><K><Q><W><G><D><R><H><T><G><I><G><F><D><Q><L><L><I><V><E><A><P><N><N><P><E><V><D><F><R><Y><R><I><F><N><A><D><G><S><E><V><E><Q><C><G><N><G><A><R><C><F><A><R><F><V><L><D><K><R><L><T><A><K><K><R><I><R><V><E><T><K><G><G><I><I><E...
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.<BOP>
B1J1W0
C5BBR3
UREG_EDWI9
Urease accessory protein UreG
Edwardsiella
<M><K><K><I><I><R><V><G><I><G><G><P><V><G><S><G><K><T><A><I><I><E><V><I><T><P><R><L><M><Q><R><G><I><K><P><L><I><I><T><N><D><I><V><T><T><E><D><A><K><Q><V><K><R><T><L><K><G><I><L><D><E><E><K><I><V><G><V><E><T><G><A><C><P><H><T><A><V><R><E><D><P><S><M><N><I><A><A><V><E><E><L><E><A><R><F><P><D><S><D><V><I><M><I><E><S><G><G...
Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.<BOP>
C5BBR3
B3MU92
NUBP1_DROAN
Cytosolic Fe-S cluster assembly factor NUBP1 homolog
Sophophora
<M><E><A><P><P><E><H><C><P><G><V><E><S><E><Q><A><G><K><V><S><A><C><A><G><C><P><N><Q><G><I><C><S><D><P><N><R><K><V><E><D><P><G><K><A><L><V><A><E><S><L><K><D><V><K><N><K><L><L><I><L><S><G><K><G><G><V><G><K><S><T><V><T><S><L><L><T><R><Y><L><A><R><S><C><P><N><S><N><F><G><V><L><D><I><D><I><C><G><P><S><Q><P><R><L><L><G><A><L...
Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.<BOP>
B3MU92
P04575
UCP1_MESAU
Thermogenin
Mesocricetus
<M><V><N><P><T><T><S><E><V><H><P><T><M><G><V><K><I><F><S><A><G><V><A><A><C><L><A><D><I><I><T><F><P><L><D><T><A><K><V><R><L><Q><I><Q><G><E><G><Q><I><S><S><T><I><R><Y><K><G><V><L><G><T><I><T><T><L><A><K><T><E><G><L><P><K><L><Y><S><G><L><P><A><G><I><Q><R><Q><I><S><F><A><S><L><R><I><G><L><Y><D><T><V><Q><E><Y><F><S><S><G><K...
Mitochondrial protein responsible for thermogenic respiration, a specialized capacity of brown adipose tissue and beige fat that participates in non-shivering adaptive thermogenesis to temperature and diet variations and more generally to the regulation of energy balance. Functions as a long-chain fatty acid/LCFA and p...
P04575
Q47UW8
CYSI_COLP3
Sulfite reductase [NADPH] hemoprotein beta-component
Colwellia
<M><S><N><N><F><T><K><V><E><N><P><V><L><I><V><E><G><K><Q><A><D><N><E><R><L><K><A><E><S><D><Y><L><R><G><T><I><K><D><D><L><Q><D><R><M><T><G><G><F><T><S><D><N><F><Q><L><I><R><T><H><G><M><Y><Q><Q><D><D><R><D><I><R><A><E><R><Q><K><Q><K><L><E><P><L><H><N><V><M><L><R><A><R><L><P><G><G><I><I><N><P><T><Q><W><L><A><I><D><K><F><A...
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.<BOP>
Q47UW8
Q6MUI9
TILS_MYCMS
tRNA(Ile)-lysidine synthetase
Mycoplasma
<M><S><L><F><N><I><N><K><S><K><K><Y><L><I><A><V><S><G><G><P><D><S><V><F><L><L><C><N><I><V><K><L><V><D><P><N><D><L><V><V><C><H><V><N><Y><N><F><R><S><D><S><N><N><D><Q><M><I><V><T><N><L><C><K><Q><L><N><L><K><L><E><I><L><N><I><N><K><D><Y><S><L><L><K><Q><N><F><E><S><W><A><R><A><Q><R><Y><D><F><F><N><M><I><A><S><K><Y><Q><I><Y...
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.<BOP>
Q6MUI9
Q6TDU7
DNAI7_HUMAN
Protein phosphatase 1 regulatory subunit 54
Homo
<M><S><G><S><K><K><K><K><V><T><K><A><E><R><L><K><L><L><Q><E><E><E><E><R><R><L><K><E><E><E><E><A><R><L><K><Y><E><K><E><E><M><E><R><L><E><I><Q><R><I><E><K><E><K><W><H><R><L><E><A><K><D><L><E><R><R><N><E><E><L><E><E><L><Y><L><L><E><R><C><F><P><E><A><E><K><L><K><Q><E><T><K><L><L><S><Q><W><K><H><Y><I><Q><C><D><G><S><P><D><P...
Via its association with the multisubunit axonemal dynein complex, is potentially involved in the regulation of cilia function. May also act as a cell cycle regulator.<BOP>
Q6TDU7
P72403
RS11_STRCO
30S ribosomal protein S11
Streptomyces albidoflavus group
<M><P><P><K><G><R><Q><G><A><A><K><K><V><R><R><K><E><K><K><N><V><A><H><G><H><A><H><I><K><S><T><F><N><N><T><I><V><S><I><T><D><P><T><G><N><V><I><S><W><A><S><A><G><H><V><G><F><K><G><S><R><K><S><T><P><F><A><A><Q><M><A><A><E><S><A><A><R><R><A><Q><E><H><G><M><R><K><V><D><V><F><V><K><G><P><G><S><G><R><E><T><A><I><R><S><L><Q><A...
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.<BOP>
P72403
C4K1R9
DNAA_RICPU
Chromosomal replication initiator protein DnaA
spotted fever group
<M><S><T><N><Q><I><I><L><T><D><Q><G><D><N><Y><V><N><V><W><S><H><V><A><Q><D><L><Y><N><H><Y><G><E><T><L><Y><N><S><W><F><S><K><V><N><F><I><E><S><S><L><N><T><V><I><L><C><A><P><T><N><F><V><R><D><W><I><K><S><K><Y><S><M><V><I><L><Q><L><F><Q><H><Y><N><N><T><I><K><S><I><E><I><I><T><K><E><L><P><G><T><T><Q><T><V><T><E><L><P><T><K...
Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.<BOP>
C4K1R9
P62433
RL11_DESVH
50S ribosomal protein L11
Desulfovibrio
<M><A><K><K><E><V><A><K><I><K><L><Q><I><P><A><G><A><A><N><P><S><P><P><V><G><P><A><L><G><Q><H><G><L><N><I><M><A><F><C><K><E><F><N><A><K><T><M><E><Q><K><G><M><I><T><P><V><V><I><T><V><Y><A><D><R><S><F><S><F><I><T><K><T><P><P><A><S><V><L><L><I><K><A><A><K><L><E><K><G><S><G><E><P><N><R><N><K><V><G><S><V><T><M><A><Q><V><E><E...
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.<BOP>
P62433
Q91ZJ9
HYAL1_MOUSE
Hyaluronoglucosaminidase-1
Mus
<M><L><G><L><T><Q><H><A><Q><K><V><W><R><M><K><P><F><S><P><E><V><S><P><G><S><S><P><A><T><A><G><H><L><L><R><I><S><T><L><F><L><T><L><L><E><L><A><Q><V><C><R><G><S><V><V><S><N><R><P><F><I><T><V><W><N><G><D><T><H><W><C><L><T><E><Y><G><V><D><V><D><V><S><V><F><D><V><V><A><N><K><E><Q><S><F><Q><G><S><N><M><T><I><F><Y><R><E><E><L...
May have a role in promoting tumor progression. May block the TGFB1-enhanced cell growth.<BOP>
Q91ZJ9
Q5FIV9
COAE_LACAC
Dephosphocoenzyme A kinase
Lactobacillus
<M><T><Y><V><L><A><L><T><G><G><I><A><T><G><K><S><T><A><D><Q><F><F><K><N><K><N><I><P><V><V><D><C><D><Q><I><A><H><D><L><M><K><P><K><N><A><S><W><Q><A><I><K><D><N><F><G><T><E><Y><L><N><S><D><Q><T><I><N><R><K><K><L><G><Q><L><V><F><S><D><P><T><A><L><N><K><L><N><Q><L><T><H><P><L><I><F><D><K><T><I><Q><K><I><K><M><Y><Q><D><K><D...
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.<BOP>
Q5FIV9
Q7Z7M8
B3GN8_HUMAN
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
Homo
<M><R><C><P><K><C><L><L><C><L><S><A><L><L><T><L><L><G><L><K><V><Y><I><E><W><T><S><E><S><R><L><S><K><A><Y><P><S><P><R><G><T><P><P><S><P><T><P><A><N><P><E><P><T><L><P><A><N><L><S><T><R><L><G><Q><T><I><P><L><P><F><A><Y><W><N><Q><Q><Q><W><R><L><G><S><L><P><S><G><D><S><T><E><T><G><G><C><Q><A><W><G><A><A><A><A><T><E><I><P><D...
Beta-1,3-N-acetylglucosaminyltransferase that plays a role in the elongation of specific branch structures of multiantennary N-glycans. Has strong activity towards tetraantennary N-glycans and 2,6 triantennary glycans.<BOP>
Q7Z7M8
P31303
PRA2_USTMD
Pheromone receptor 2
Ustilago
<M><F><S><G><K><E><N><V><S><F><G><V><L><C><L><L><A><G><C><I><S><T><S><S><C><L><I><H><L><Q><A><K><N><I><G><V><L><L><M><M><F><W><C><F><T><G><L><V><N><K><G><I><N><A><L><A><F><N><N><S><L><R><L><A><W><T><L><G><C><D><L><S><A><I><I><E><R><T><W><Q><F><G><L><C><C><S><A><L><C><V><L><Q><R><L><E><G><I><A><S><L><R><Q><A><H><S><T><V...
Receptor for the A1 pheromone, a prenylated mating factor.<BOP>
P31303
A9A8I0
ARGC_METM6
N-acetyl-glutamate semialdehyde dehydrogenase
Methanococcus
<M><K><T><V><S><I><I><G><G><T><G><Y><T><G><S><E><L><L><R><L><L><S><N><H><D><N><V><E><V><L><N><V><T><S><R><K><E><A><G><K><K><L><T><D><F><H><P><Q><V><R><N><L><R><N><Y><N><D><L><E><F><Q><N><I><A><P><E><D><I><D><T><D><I><V><F><C><A><T><P><H><G><A><S><M><A><I><V><P><I><L><H><E><K><G><I><N><V><I><D><L><S><G><D><Y><R><F><E><D...
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.<BOP>
A9A8I0
Q5QHG5
LAP1_TRIRU
Leucyl aminopeptidase 1
Trichophyton
<M><K><L><L><S><V><L><A><L><S><A><T><A><T><S><V><L><G><A><S><I><P><V><D><A><R><A><E><K><F><L><I><E><L><A><P><G><E><T><R><W><V><T><E><E><E><K><W><E><L><K><R><K><G><Q><D><F><F><D><I><T><D><E><E><V><G><F><T><A><A><V><A><Q><P><A><I><A><Y><P><T><S><I><R><H><A><N><A><V><N><A><M><I><A><T><L><S><K><E><N><M><Q><R><D><L><T><K><L...
Extracellular aminopeptidase which contributes to pathogenicity.<BOP>
Q5QHG5
Q931E4
ICAC_STAAM
Intercellular adhesion protein C
Staphylococcus
<M><K><K><I><R><L><E><L><V><Y><L><R><A><I><I><C><A><I><I><I><I><T><H><L><L><T><Q><I><T><L><K><H><E><N><M><E><G><G><S><L><V><L><Q><F><Y><I><R><N><I><V><I><F><G><T><P><C><F><I><I><L><S><Q><L><L><T><T><L><N><Y><Q><K><V><T><Y><R><Y><L><T><T><R><V><K><Y><I><L><I><P><Y><I><L><M><G><L><F><Y><S><Y><S><E><S><L><L><T><D><S><S><F...
Presumably involved in the export of the biofilm adhesin polysaccharide poly-beta-1,6-N-acetyl-D-glucosamine (PNAG, also referred to as PIA) across the cell membrane.<BOP>
Q931E4
Q8FVF3
LEU3_BRUSU
Beta-IPM dehydrogenase
Brucella
<M><A><S><R><K><L><L><L><L><P><G><D><G><I><G><P><E><A><M><A><E><V><R><K><V><I><A><F><L><N><S><D><L><N><L><G><F><E><T><E><E><G><L><V><G><G><C><A><Y><D><A><H><G><Q><A><I><S><D><A><D><M><E><K><A><L><A><A><D><A><V><L><F><G><A><V><G><G><P><K><W><D><S><V><P><Y><E><V><R><P><E><A><G><L><L><R><L><R><K><D><M><Q><L><Y><A><N><L><R...
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.<BOP>
Q8FVF3
B6JCR2
FABA_AFIC5
Trans-2-decenoyl-[acyl-carrier-protein] isomerase
Afipia
<M><R><E><R><Q><N><S><Y><E><Y><E><D><L><L><A><C><G><R><G><E><L><F><G><P><G><N><A><Q><L><P><L><P><P><M><L><M><F><D><R><I><V><E><I><T><E><T><G><G><E><F><G><K><G><V><I><R><A><E><L><D><V><K><P><D><L><W><F><F><G><C><H><F><K><G><D><P><V><M><P><G><C><L><G><L><D><A><L><W><Q><M><V><G><F><F><L><G><W><T><G><G><S><G><R><G><R><A><L...
Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active ...
B6JCR2
Q8CQB3
BIOB_STAES
Biotin synthase
Staphylococcus
<M><L><N><R><E><P><L><T><K><E><E><A><L><T><I><F><E><S><S><E><L><D><T><F><D><L><L><N><E><A><Y><T><V><R><K><H><Y><Y><G><K><K><V><K><L><N><M><I><L><N><A><K><S><G><I><C><A><E><D><C><G><Y><C><G><Q><S><V><K><M><K><E><K><Q><R><Y><A><L><V><E><Q><D><Q><I><K><E><G><A><Q><V><A><T><E><N><Q><I><G><T><Y><C><I><V><M><S><G><R><G><P><S...
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.<BOP>
Q8CQB3
Q5X1A9
NUOC_LEGPA
NDH-1 subunit C
Legionella
<M><T><K><N><E><Y><L><I><E><K><L><Q><A><N><L><A><N><H><I><T><E><L><T><S><A><Y><G><E><V><T><I><E><C><E><V><H><N><L><L><P><V><M><I><E><L><R><D><R><E><E><F><S><F><D><Q><L><I><D><L><C><G><V><D><Y><L><H><Y><G><D><Y><D><W><E><T><E><S><A><T><E><H><G><F><S><R><G><V><E><R><Q><E><A><K><A><Y><A><V><N><K><P><R><F><A><V><V><Y><H><L...
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are t...
Q5X1A9
Q8D8E5
NRFA_VIBVU
Ammonia-forming cytochrome c nitrite reductase
Vibrio
<M><S><I><K><H><W><M><A><S><S><V><S><V><T><A><L><V><M><T><A><L><L><N><I><T><A><V><S><A><E><E><K><G><L><V><D><P><R><N><D><A><F><E><Q><N><H><P><D><Q><Y><Q><S><W><K><K><T><S><E><S><V><E><I><E><D><A><L><A><E><D><P><N><M><V><I><L><W><A><G><Y><G><F><A><K><D><Y><N><K><A><R><G><H><F><Y><A><L><D><D><V><R><Q><T><L><R><T><G><G><P...
Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process.<BOP>
Q8D8E5
A6H2D7
ATPA_FLAPJ
F-ATPase subunit alpha
Flavobacterium
<M><A><E><I><K><P><A><E><I><S><A><I><L><K><K><Q><V><E><G><F><E><S><G><A><T><L><E><E><V><G><S><V><L><Q><V><G><D><G><I><A><R><I><Y><G><L><S><N><V><Q><Y><G><E><L><V><E><F><D><N><G><L><E><G><I><V><L><N><L><E><E><D><N><V><G><V><V><L><L><G><A><S><T><G><I><K><E><G><S><T><A><K><R><T><Q><R><I><A><S><L><K><V><G><E><Q><M><V><G><R...
Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.<BOP>
A6H2D7
Q54T49
APT11_DICDI
Palmitoyl-protein hydrolase
Dictyostelium
<M><I><K><T><I><L><K><N><S><Y><I><Q><K><E><I><T><T><H><S><A><T><V><I><F><S><H><G><L><G><D><S><G><A><G><W><I><E><V><M><E><E><I><Q><S><R><N><N><G><H><I><R><F><I><C><P><N><A><P><I><Q><A><V><T><L><N><G><G><F><K><M><P><S><W><Y><D><I><K><S><L><S><S><R><G><D><E><D><P><A><Q><V><D><E><S><K><N><I><I><E><T><I><I><K><H><E><M><E><E...
Hydrolyzes fatty acids from S-acylated cysteine residues in proteins with a strong preference for palmitoylated G-alpha proteins over other acyl substrates. Mediates the deacylation of G-alpha proteins such as GPA1 in vivo, but has weak or no activity toward palmitoylated Ras proteins. Has weak lysophospholipase activi...
Q54T49
D2Y2A6
H13F1_CYRHA
Hainantoxin-XIII-6
Haplopelma
<M><K><T><A><I><F><T><V><V><L><A><L><A><V><F><A><V><L><S><F><G><W><E><A><N><E><K><A><L><S><E><E><F><T><E><L><I><H><E><K><E><A><A><S><E><T><E><A><R><E><C><R><Y><F><W><G><E><C><H><D><R><M><P><C><C><D><W><L><V><C><R><Y><K><W><P><I><T><Y><N><I><C><V><W><N><R><T><F><P><E><K>
Ion channel inhibitor.<BOP>
D2Y2A6
A1VQ18
RIMO_POLNA
Ribosome maturation factor RimO
Polaromonas
<M><N><E><I><K><E><K><I><P><R><I><G><M><V><S><L><G><C><P><K><A><L><T><D><S><E><L><I><L><T><R><L><S><A><E><G><Y><Q><T><S><K><T><F><E><G><A><D><L><V><I><V><N><T><C><G><F><I><D><D><A><V><R><E><S><L><D><T><I><G><E><A><L><A><A><N><G><K><V><I><V><T><G><C><L><G><A><K><S><G><D><N><G><S><N><L><V><R><Q><M><H><P><S><V><L><A><V><T...
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.<BOP>
A1VQ18
Q81J19
RS11_BACCR
30S ribosomal protein S11
Bacillus cereus group
<M><A><R><K><T><N><T><R><K><K><R><V><K><K><N><I><E><A><G><I><A><H><I><R><S><T><F><N><N><T><I><V><T><L><T><D><T><H><G><N><A><L><S><W><S><S><A><G><A><L><G><F><R><G><S><R><K><S><T><P><F><A><A><Q><M><A><A><E><T><A><A><K><A><A><M><E><H><G><L><K><T><L><E><V><T><V><K><G><P><G><A><G><R><E><A><A><I><R><A><L><Q><A><A><G><L><E><V...
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.<BOP>
Q81J19
B7UH56
TRMD_ECO27
tRNA [GM37] methyltransferase
Escherichia
<M><W><I><G><I><I><S><L><F><P><E><M><F><R><A><I><T><D><Y><G><V><T><G><R><A><V><K><N><G><L><L><S><I><Q><S><W><S><P><R><D><F><T><Y><D><R><H><R><T><V><D><D><R><P><Y><G><G><G><P><G><M><L><M><M><V><Q><P><L><R><D><A><I><H><A><A><K><A><A><A><G><E><G><A><K><V><I><Y><L><S><P><Q><G><R><K><L><D><Q><A><G><V><S><E><L><A><T><N><Q><K...
Specifically methylates guanosine-37 in various tRNAs.<BOP>
B7UH56
A7ZWC6
FABZ_ECOHS
Beta-hydroxyacyl-ACP dehydratase
Escherichia
<M><T><T><N><T><H><T><L><Q><I><E><E><I><L><E><L><L><P><H><R><F><P><F><L><L><V><D><R><V><L><D><F><E><E><G><R><F><L><R><A><V><K><N><V><S><V><N><E><S><F><F><Q><G><H><F><P><G><K><P><I><F><P><G><V><L><I><L><E><A><M><A><Q><A><T><G><I><L><A><F><K><S><V><G><K><L><E><P><G><E><L><Y><Y><F><A><G><I><D><E><A><R><F><K><R><P><V><V><P...
Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.<BOP>
A7ZWC6
B9FI63
ERA_ORYSJ
GTP-binding protein Era-like
Oryza sativa
<M><E><L><G><L><A><L><R><L><V><A><P><P><P><R><L><P><C><R><A><L><Q><P><P><P><M><P><C><F><S><P><C><A><A><R><R><S><R><I><R><S><S><R><L><E><R><R><V><G><V><V><V><S><G><G><S><M><A><S><L><A><M><E><E><E><E><E><E><E><W><E><E><A><E><E><E><A><E><G><W><Q><E><E><E><A><A><V><V><T><T><R><P><R><L><E><L><I><E><K><P><D><R><S><L><C><L><L...
Nuclear genome-encoded probable GTPase involved in ribosome biogenesis in chloroplasts. Plays a role in 16S rRNA maturation in plastids and may contribute to the assembly of the small (30S) ribosomal subunit.<BOP>
B9FI63
B7VPF6
IHFA_VIBA3
Integration host factor subunit alpha
Vibrio
<M><A><L><T><K><A><D><L><A><E><N><L><F><E><T><L><G><Y><S><K><R><D><A><K><E><T><V><E><V><F><F><E><E><V><R><K><A><L><E><N><G><E><Q><V><K><L><S><G><F><G><N><F><D><L><R><E><K><N><E><R><P><G><R><N><P><K><T><G><E><D><I><P><I><S><A><R><R><V><V><T><F><R><P><G><Q><K><L><K><A><R><V><E><N><I><K><I><E><K>
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.<BOP>
B7VPF6
B0BTC2
CYSG_ACTPJ
Sirohydrochlorin ferrochelatase
Actinobacillus
<M><N><Y><L><P><I><F><V><D><L><K><N><R><P><V><L><V><V><G><G><G><H><I><A><V><R><K><I><D><A><L><L><K><A><G><A><S><V><K><V><V><A><E><K><L><H><S><S><L><Q><S><L><T><D><E><G><K><V><E><W><I><A><K><T><F><E><A><N><Q><V><T><N><S><Y><L><V><I><A><A><T><D><D><N><A><L><N><Q><L><V><F><E><T><A><E><S><Q><Q><R><L><V><N><V><V><D><D><Q><P...
Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yie...
B0BTC2
Q73EM5
PCRB_BACC1
Glycerol-1-phosphate heptaprenyltransferase
Bacillus cereus group
<M><Y><D><I><S><G><W><K><H><V><F><K><L><D><P><N><K><E><L><S><E><E><H><L><E><M><I><C><E><S><G><T><D><A><V><I><V><G><G><S><D><G><V><T><I><D><N><V><L><H><M><L><V><S><I><R><R><Y><A><V><P><C><V><L><E><V><S><D><V><E><A><I><T><P><G><F><D><F><Y><Y><I><P><S><V><L><N><S><R><K><V><E><W><V><T><G><V><H><H><E><A><L><K><E><F><G><D><I...
Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1...
Q73EM5
O78494
CYF_GUITH
Cytochrome f
Guillardia
<M><I><N><L><F><L><L><K><Y><K><T><A><F><S><T><F><L><K><P><F><A><Y><L><S><L><I><L><S><V><C><F><Y><S><I><Q><A><Q><A><F><P><V><F><A><Q><Q><A><Y><E><N><P><R><E><A><T><G><R><I><V><C><A><N><C><H><L><A><Q><K><P><V><E><I><E><V><P><Q><A><V><L><P><D><T><V><F><E><A><V><V><E><V><P><Y><D><L><S><L><Q><Q><V><T><G><N><G><T><K><G><P><L...
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.<BOP>
O78494
P31737
GSPI_AERHY
General secretion pathway protein I
Aeromonas
<M><N><A><R><G><M><T><L><L><E><V><M><V><A><L><A><V><F><A><I><A><G><L><A><V><M><K><T><A><S><E><H><L><S><A><L><N><Y><L><E><E><K><T><L><A><T><W><V><V><E><N><Q><L><V><Q><Q><K><L><E><A><K><W><P><G><D><S><W><V><E><G><G><E><Q><M><A><G><Q><T><W><Y><W><R><Y><R><G><V><A><T><A><D><N><N><F><K><A><L><D><M><E><V><R><T><A><P><K><A><E...
Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Part of the pseudopilus tip complex that is critical for the recognition and binding of secretion substrates.<BOP>
P31737
Q864I7
MSHR_TRAAU
Melanocortin receptor 1
Trachypithecus
<M><P><V><Q><G><S><Q><R><R><L><L><G><S><L><N><S><T><P><T><A><T><P><R><L><G><L><A><A><N><Q><T><G><A><R><C><L><E><V><S><I><P><D><G><L><F><L><S><L><G><L><V><S><L><V><E><N><V><L><V><V><V><A><I><A><R><N><R><N><L><H><S><P><M><Y><C><F><I><C><C><L><A><L><S><D><L><L><V><S><G><S><N><M><L><E><T><A><V><I><L><L><L><E><A><G><A><L><A...
Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Mediates melanogenesis, the production of eumelanin (black/brown) and phaeomelanin (red/yellow), via regulation of cAMP signaling in melanocytes.<BOP>
Q864I7
Q15QR6
ENO_PSEA6
2-phosphoglycerate dehydratase
Pseudoalteromonas
<M><S><N><I><S><K><I><I><G><R><E><I><M><D><S><R><G><N><P><T><V><E><A><D><V><Y><L><E><S><G><A><M><G><R><A><T><A><P><S><G><A><S><T><G><S><R><E><A><L><E><L><R><D><G><D><K><S><R><Y><L><G><K><G><V><L><K><A><V><A><A><I><N><E><D><I><A><P><A><L><L><G><N><S><A><F><D><Q><K><K><V><D><Q><I><M><I><D><L><D><G><T><E><N><K><E><K><F><G...
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.<BOP>
Q15QR6
Q11E17
HUTI_CHESB
Imidazolone-5-propionate hydrolase
unclassified Chelativorans
<M><T><R><N><N><F><S><G><A><A><A><H><S><A><R><S><I><W><R><N><G><R><L><A><T><L><R><E><D><L><Q><G><L><G><I><V><E><N><G><A><V><V><C><E><G><G><R><I><L><F><A><G><P><E><G><E><L><P><A><E><L><I><E><N><T><E><I><T><D><L><E><G><R><W><V><T><P><G><L><V><D><C><H><T><H><I><V><Y><G><G><N><R><A><R><E><F><E><M><R><L><Q><G><A><T><Y><E><E...
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.<BOP>
Q11E17
B8ZRT3
RBFA_MYCLB
Ribosome-binding factor A
Mycobacterium
<M><A><D><Q><A><R><A><R><R><L><A><K><R><I><C><T><I><V><A><S><A><I><E><F><E><I><K><D><P><G><L><D><G><V><T><I><V><D><V><K><V><T><A><D><L><H><D><A><T><V><F><Y><T><V><M><G><R><T><L><E><D><A><P><D><Y><T><A><A><T><A><A><L><N><R><A><K><G><T><L><R><S><K><V><G><A><G><T><G><V><R><F><T><P><T><L><T><F><I><R><D><T><T><S><D><S><V><A...
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal heli...
B8ZRT3
Q8X6X9
THIC_ECO57
Thiamine biosynthesis protein ThiC
Escherichia
<M><S><A><T><K><L><T><R><R><E><Q><R><A><Q><A><Q><H><F><I><D><T><L><E><G><T><A><F><P><N><S><K><R><I><Y><I><T><G><T><Q><P><G><V><R><V><P><M><R><E><I><Q><L><S><P><T><L><I><G><G><S><K><E><Q><P><Q><Y><E><E><N><E><A><I><P><V><Y><D><T><S><G><P><Y><G><D><P><Q><I><A><I><N><V><Q><Q><G><L><A><K><L><R><Q><P><W><I><D><A><R><G><D><T...
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.<BOP>
Q8X6X9
Q07YC8
GCSH_SHEFN
Glycine cleavage system H protein
Shewanella
<M><S><T><I><P><A><D><L><K><Y><A><S><S><H><E><W><I><R><K><E><S><D><G><S><Y><T><V><G><I><T><E><H><A><Q><E><L><L><G><D><M><V><F><V><E><L><P><E><V><G><D><T><V><T><A><G><E><D><C><A><V><A><E><S><V><K><A><A><S><D><I><Y><A><P><I><S><G><E><V><I><A><V><N><E><S><L><E><D><S><P><E><L><V><N><S><D><A><F><G><D><G><W><F><F><R><V><M><P...
The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.<BOP>
Q07YC8