accession stringlengths 6 10 | name stringlengths 6 11 | Full Name stringlengths 1 147 ⌀ | taxon stringlengths 3 46 ⌀ | sequence stringlengths 48 2.3k | function stringlengths 11 1.34k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
B9DVR0 | RPOY_STRU0 | Transcriptase subunit epsilon | Streptococcus | <M><I><Y><K><I><F><Y><Q><E><T><K><E><R><S><P><R><R><E><K><T><Q><A><L><Y><L><E><I><D><A><E><T><E><L><E><G><R><I><K><A><R><K><L><I><E><E><K><T><A><Y><N><V><E><Y><I><E><L><L><S><D><K><H><L><E><Y><E><K><E><T><G><V><F><A><L><T><E><L> | A non-essential component of RNA polymerase (RNAP).<BOP> | B9DVR0 |
Q96JP5 | ZFP91_HUMAN | Zinc finger protein 91 homolog | Homo | <M><P><G><E><T><E><E><P><R><P><P><E><Q><Q><D><Q><E><G><G><E><A><A><K><A><A><P><E><E><P><Q><Q><R><P><P><E><A><V><A><A><A><P><A><G><T><T><S><S><R><V><L><R><G><G><R><D><R><G><R><A><A><A><A><A><A><A><A><A><V><S><R><R><R><K><A><E><Y><P><R><R><R><R><S><S><P><S><A><R><P><P><D><V><P><G><Q><Q><P><Q><A><A><K><S><P><S><P><V><Q><G... | Atypical E3 ubiquitin-protein ligase that mediates 'Lys-63'-linked ubiquitination of MAP3K14/NIK, leading to stabilize and activate MAP3K14/NIK. It thereby acts as an activator of the non-canonical NF-kappa-B2/NFKB2 pathway. May also play an important role in cell proliferation and/or anti-apoptosis.<BOP> | Q96JP5 |
Q6BWS4 | RSA3_DEBHA | Ribosome assembly protein 3 | Debaryomyces | <M><A><A><A><Q><V><K><N><E><K><I><G><N><P><K><S><N><R><R><R><R><K><K><R><R><T><E><D><F><S><S><D><S><E><S><S><S><S><S><S><S><D><E><S><M><D><D><A><A><E><E><P><K><P><I><K><E><T><K><S><I><N><I><D><D><I><D><I><D><S><D><K><E><T><D><V><N><S><Q><E><K><Q><N><S><L><R><P><E><P><L><S><N><E><T><H><E><K><L><S><N><I><K><L><T><T><S><K... | Required for efficient biogenesis of the 60S ribosomal subunit.<BOP> | Q6BWS4 |
Q8TJ20 | GGGPS_METAC | Phosphoglycerol geranylgeranyltransferase | Methanosarcina | <M><Q><V><E><A><H><L><Q><K><I><I><D><Q><D><G><K><V><H><L><T><L><I><D><P><A><S><Q><T><P><E><R><A><A><E><I><A><L><A><A><V><E><G><G><T><D><A><I><M><I><G><G><S><T><G><A><S><G><T><L><L><D><E><T><V><I><K><I><K><E><K><V><N><V><P><T><I><L><F><P><G><S><S><A><G><L><S><S><Y><A><D><A><V><F><F><M><S><L><L><N><S><R><D><L><G><Y><V><I... | Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.<BOP> | Q8TJ20 |
Q5FWQ6 | DAW1_XENLA | WD repeat-containing protein 69 | Xenopus | <M><R><L><K><R><F><L><L><R><Y><F><P><P><G><I><I><L><E><Y><E><K><G><G><E><L><K><T><K><A><I><D><L><L><E><L><S><P><T><T><D><V><D><L><V><V><G><E><I><Q><K><A><E><P><L><I><T><A><S><R><T><Q><Q><V><K><Q><L><I><L><R><L><Q><E><K><I><G><Q><Q><D><S><R><Q><F><Y><L><F><K><V><L><R><A><H><I><L><P><L><T><N><V><A><F><N><K><S><G><S><S><F... | May play a role in axonemal outer row dynein assembly.<BOP> | Q5FWQ6 |
B6J5D6 | RS19_COXB1 | 30S ribosomal protein S19 | Coxiella | <M><P><R><S><T><N><K><G><P><F><V><D><H><H><L><M><K><K><V><D><Q><A><Q><K><E><G><S><K><R><P><I><K><T><W><S><R><R><S><M><V><V><P><E><M><V><G><L><T><I><A><I><H><N><G><R><Q><H><V><P><V><Y><I><S><E><N><M><V><G><H><K><L><G><E><F><A><I><T><R><T><F><R><A><H><S><G><D><R><K><A><K><K><E><G><E><K> | Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.<BOP> | B6J5D6 |
Q1LZE6 | CHPT1_BOVIN | Diacylglycerol cholinephosphotransferase 1 | Bos | <M><A><A><G><A><G><A><R><P><A><P><R><W><L><K><A><L><T><E><P><L><S><A><A><Q><L><R><R><L><E><E><H><R><Y><T><A><A><G><V><S><L><L><E><P><P><L><Q><L><Y><W><T><W><L><L><Q><W><I><P><L><W><M><A><P><N><S><I><T><L><L><G><L><A><I><N><M><L><T><T><L><V><L><I><S><Y><C><P><T><V><T><E><E><A><P><Y><W><T><Y><L><L><C><A><L><G><L><F><I><Y... | Catalyzes phosphatidylcholine biosynthesis from CDP-choline. It thereby plays a central role in the formation and maintenance of vesicular membranes.<BOP> | Q1LZE6 |
C4LL63 | EFTU_CORK4 | Elongation factor Tu | Corynebacterium | <M><A><K><A><K><F><D><R><S><K><P><H><V><N><I><G><T><I><G><H><V><D><H><G><K><T><T><T><T><A><A><I><T><K><V><L><S><E><K><Y><P><E><E><N><Q><A><F><A><F><D><A><I><D><K><A><P><E><E><K><E><R><G><I><T><I><N><I><A><H><V><E><Y><S><T><P><K><R><H><Y><A><H><V><D><A><P><G><H><A><D><Y><I><K><N><M><I><T><G><A><A><Q><M><D><G><A><I><L><V... | This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.<BOP> | C4LL63 |
Q50570 | FDHB_METTF | Formate dehydrogenase subunit beta | Methanothermobacter | <M><V><E><V><N><D><M><Y><Y><A><F><S><K><N><E><E><I><A><E><K><G><E><Y><G><G><A><V><T><S><L><L><K><F><L><L><E><E><G><M><V><D><A><V><L><A><V><K><K><G><S><D><L><Y><D><A><V><P><T><L><I><T><E><P><E><K><V><I><E><S><A><G><S><L><H><C><G><T><L><N><I><A><K><V><I><T><R><Y><L><N><G><A><K><D><I><K><I><A><V><T><T><K><P><C><D><A><M><T... | Catalyzes the oxidation of formate.<BOP> | Q50570 |
B9JAL7 | DXS_AGRRK | 1-deoxyxylulose-5-phosphate synthase | Agrobacterium tumefaciens complex | <M><T><H><M><P><E><T><P><L><L><D><Q><V><H><Y><P><S><D><L><R><K><L><E><D><R><D><L><P><Q><L><A><R><E><V><R><D><E><M><I><D><A><V><S><R><T><G><G><H><L><G><A><G><L><G><V><V><E><L><T><I><A><I><H><N><V><F><D><T><P><N><D><R><L><I><F><D><V><G><H><Q><C><Y><P><H><K><I><L><T><G><R><R><D><R><I><R><T><L><R><Q><E><G><G><I><S><G><F><T... | Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).<BOP> | B9JAL7 |
Q745R0 | Y256_MYCPA | Putative S-adenosyl-L-methionine-dependent methyltransferase MAP_0256 | Mycobacterium avium complex (MAC) | <M><P><R><T><D><N><D><S><W><D><I><T><Q><S><V><G><A><T><A><L><G><V><A><A><A><R><A><A><E><T><E><S><E><N><P><L><I><S><D><P><F><A><R><I><F><V><E><A><A><G><K><G><M><W><S><I><Y><A><D><P><A><L><L><T><K><A><D><D><L><E><P><D><L><R><G><R><L><Q><L><M><I><D><F><M><A><T><R><T><A><F><F><D><E><F><F><L><A><A><A><D><A><G><V><R><Q><V><V... | Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.<BOP> | Q745R0 |
Q3JLQ0 | 1A1D_BURP1 | 1-aminocyclopropane-1-carboxylate deaminase | pseudomallei group | <M><N><L><Q><K><F><P><R><Y><P><L><T><F><G><P><T><P><I><Q><P><L><K><R><L><S><A><H><L><G><G><K><V><E><L><Y><A><K><R><D><D><C><N><S><G><L><A><F><G><G><N><K><T><R><K><L><E><Y><L><I><P><D><A><L><A><Q><G><C><D><T><L><V><S><I><G><G><I><Q><S><N><Q><T><R><Q><V><A><A><V><A><A><H><L><G><M><K><C><V><L><V><Q><E><N><W><V><N><Y><H><D... | Catalyzes a cyclopropane ring-opening reaction, the irreversible conversion of 1-aminocyclopropane-1-carboxylate (ACC) to ammonia and alpha-ketobutyrate. Allows growth on ACC as a nitrogen source.<BOP> | Q3JLQ0 |
Q5UZ63 | FER2_HALMA | Ferredoxin-2 | Haloarcula | <M><V><E><F><L><N><F><E><V><L><E><D><H><G><W><A><L><Q><D><E><D><L><F><A><K><A><A><D><A><N><L><Q><S><T><D><F><G><R><F><Y><V><D><P><N><D><T><L><L><E><A><A><E><K><N><G><F><A><W><P><F><A><C><R><G><G><A><C><T><N><C><A><V><A><V><V><D><G><E><M><P><S><P><A><S><H><I><L><P><P><E><L><T><E><K><G><I><R><L><S><C><I><A><A><P><V><S><D... | Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.<BOP> | Q5UZ63 |
A1WK52 | RL1_VEREI | 50S ribosomal protein L1 | Verminephrobacter | <M><P><Q><L><T><K><K><Q><K><A><M><Q><G><K><V><D><S><T><R><L><Y><A><F><T><D><A><L><V><L><V><K><Q><A><A><T><A><K><F><D><E><S><I><D><V><A><V><Q><L><G><I><D><A><K><K><S><D><Q><V><V><R><G><A><V><V><L><P><N><G><T><G><K><I><T><R><V><A><V><F><A><Q><G><A><K><A><E><E><A><K><A><A><G><A><D><V><V><G><M><D><D><L><A><A><M><V><K><A><G... | Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.<BOP> | A1WK52 |
A0LV90 | COAD_ACIC1 | Pantetheine-phosphate adenylyltransferase | Acidothermus | <M><R><K><A><V><C><P><G><S><F><D><P><V><T><N><G><H><L><D><I><I><S><R><A><A><A><L><Y><D><E><V><T><V><A><V><L><V><N><K><A><K><R><A><L><F><S><V><E><E><R><M><D><M><V><R><E><A><T><A><Q><Y><P><N><V><V><V><E><S><F><S><G><L><L><V><D><F><C><R><A><R><G><I><P><V><I><I><K><G><L><R><A><V><S><D><F><D><Y><E><L><Q><M><A><Q><M><N><H><S... | Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.<BOP> | A0LV90 |
Q5AVI2 | SHO1_EMENI | Osmosensor sho1 | Aspergillus subgen. Nidulantes | <M><A><A><L><R><A><S><N><L><L><G><D><P><F><A><L><A><T><S><S><I><A><M><L><G><W><L><I><A><F><I><A><S><I><A><A><D><V><Q><D><P><Y><P><S><F><Q><W><W><A><I><A><Y><S><F><C><C><N><V><G><V><I><V><V><F><L><T><D><T><G><L><T><Y><G><V><A><V><V><G><Y><L><A><A><S><L><V><M><N><S><I><S><A><N><S><M><F><N><S><K><S><T><S><S><F><Q><A><A><G... | Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.<BOP> | Q5AVI2 |
Q5HL18 | PDRP2_STAEQ | Putative pyruvate, phosphate dikinase regulatory protein 2 | Staphylococcus | <M><K><D><N><N><E><V><L><K><L><F><I><V><S><D><S><I><G><E><T><A><Q><R><M><I><H><A><T><L><T><Q><F><P><D><L><T><Q><V><E><I><K><K><F><P><Y><I><K><D><E><Q><E><F><L><N><V><L><Q><L><A><K><E><Q><N><A><I><V><A><T><T><L><V><S><E><S><F><N><A><L><G><H><Q><F><A><N><E><H><Q><I><P><Y><V><D><Y><M><S><E><L><I><S><I><I><K><Q><H><T><H><A... | Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.<BOP> | Q5HL18 |
A1SNW4 | UNG_NOCSJ | Uracil-DNA glycosylase | Nocardioides | <M><S><A><L><A><G><L><V><D><K><G><L><M><A><P><D><W><A><Q><A><L><A><P><V><D><E><Q><I><A><A><M><G><R><F><L><R><E><E><L><A><A><G><R><T><Y><Q><P><T><G><E><W><V><F><R><A><F><Q><R><P><L><A><D><V><R><V><L><I><V><G><Q><D><P><Y><P><N><P><E><H><P><I><G><L><S><F><A><V><R><G><D><V><W><P><L><P><P><S><L><V><N><I><Y><T><E><L><R><D><D... | Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.<BOP> | A1SNW4 |
Q60715 | P4HA1_MOUSE | Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1 | Mus | <M><I><W><V><V><L><M><M><A><I><L><L><P><Q><S><L><A><H><P><G><F><F><T><S><I><G><Q><M><T><D><L><I><H><N><E><K><D><L><V><T><S><L><K><D><Y><I><K><A><E><E><D><K><L><E><Q><I><K><K><W><A><E><K><L><D><R><L><T><S><T><A><T><K><D><P><E><G><F><V><G><H><P><V><N><A><F><K><L><M><K><R><L><N><T><E><W><S><E><L><E><N><L><I><L><K><D><M><S... | Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.<BOP> | Q60715 |
B1II43 | PNP_CLOBK | Polynucleotide phosphorylase | Clostridium | <M><I><H><T><L><E><T><T><V><A><G><R><K><M><K><V><D><F><G><K><T><G><M><L><S><N><A><A><I><F><M><S><Y><G><D><T><V><V><M><I><N><A><N><A><S><K><E><P><R><E><G><I><D><F><F><P><L><S><V><D><Y><E><E><R><L><Y><S><V><G><K><I><P><G><G><F><I><K><R><E><G><K><P><S><D><K><S><I><L><H><A><R><S><I><D><R><P><L><R><P><L><F><P><K><G><Y><R><N... | Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.<BOP> | B1II43 |
Q9Y2B0 | CNPY2_HUMAN | Transmembrane protein 4 | Homo | <M><K><G><W><G><W><L><A><L><L><L><G><A><L><L><G><T><A><W><A><R><R><S><Q><D><L><H><C><G><A><C><R><A><L><V><D><E><L><E><W><E><I><A><Q><V><D><P><K><K><T><I><Q><M><G><S><F><R><I><N><P><D><G><S><Q><S><V><V><E><V><P><Y><A><R><S><E><A><H><L><T><E><L><L><E><E><I><C><D><R><M><K><E><Y><G><E><Q><I><D><P><S><T><H><R><K><N><Y><V><R... | Positive regulator of neurite outgrowth by stabilizing myosin regulatory light chain (MRLC). It prevents MIR-mediated MRLC ubiquitination and its subsequent proteasomal degradation.<BOP> | Q9Y2B0 |
Q2LVL5 | LPXD_SYNAS | UDP-3-O-acylglucosamine N-acyltransferase | Syntrophus | <M><K><K><S><I><N><E><I><A><D><F><L><G><G><K><V><V><G><D><G><G><I><L><I><K><A><V><R><G><I><D><E><A><G><P><G><D><I><T><F><V><A><N><P><Q><Y><E><K><K><L><N><E><T><G><A><S><A><V><L><V><T><R><D><T><E><R><P><G><E><N><V><T><L><I><Q><V><D><D><P><Y><V><S><L><G><K><L><L><T><I><F><Y><P><E><E><R><E><K><P><G><I><S><A><Q><A><I><V><E... | Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.<BOP> | Q2LVL5 |
Q2KWD6 | YBEY_BORA1 | Endoribonuclease YbeY | Bordetella | <M><K><A><G><E><P><G><L><A><L><A><V><Q><Y><A><V><A><E><P><R><L><P><R><W><R><L><R><R><W><A><G><Y><A><L><A><G><A><A><A><D><G><L><I><D><F><Q><A><A><E><L><N><V><R><L><V><G><Q><A><E><G><R><R><L><N><A><D><F><R><G><R><D><Y><A><T><N><V><L><T><F><E><Y><G><V><D><P><L><G><T><A><R><G><D><I><V><I><C><A><P><V><L><A><R><E><A><R><E><Q... | Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.<BOP> | Q2KWD6 |
Q8S8W4 | CYF_ATRBE | Cytochrome f | Atropa | <M><Q><T><R><N><A><F><S><W><L><K><K><Q><I><T><R><S><I><S><V><S><L><M><I><Y><I><L><T><R><T><S><I><S><S><A><Y><P><I><F><A><Q><Q><G><Y><E><N><P><R><E><A><T><G><R><I><V><C><A><N><C><H><L><A><N><K><P><V><E><I><E><V><P><Q><A><V><L><P><D><T><V><F><E><A><V><V><R><I><P><Y><D><M><Q><L><K><Q><V><L><A><N><G><K><K><G><G><L><N><V><G... | Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.<BOP> | Q8S8W4 |
P29935 | COBU_SINSX | N(1)-alpha-phosphoribosyltransferase | Sinorhizobium | <M><S><A><S><G><L><P><F><D><D><F><R><E><L><L><R><N><L><P><G><P><D><A><A><A><L><V><A><A><R><E><R><D><A><Q><L><T><K><P><P><G><A><L><G><R><L><E><E><I><A><F><W><L><A><A><W><T><G><K><A><P><V><V><N><R><P><L><V><A><I><F><A><G><N><H><G><V><T><R><Q><G><V><T><P><F><P><S><S><V><T><A><Q><M><V><E><N><F><A><A><G><G><A><A><I><N><Q><I... | Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).<BOP> | P29935 |
Q9BIG5 | GPA4_CAEEL | Guanine nucleotide-binding protein alpha-4 subunit | Caenorhabditis | <M><G><C><F><H><S><T><G><S><E><A><K><K><R><S><K><L><I><D><E><Q><L><R><H><D><H><E><R><C><V><G><E><I><K><L><L><L><L><G><A><G><E><S><G><K><S><T><I><V><R><Q><M><R><I><L><H><E><T><G><F><N><K><Q><E><Q><M><A><Y><R><P><V><V><F><S><N><M><V><Q><S><M><L><A><I><L><K><A><M><Q><P><L><N><I><S><F><T><D><A><A><R><E><E><D><A><R><M><F><I... | Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.<BOP> | Q9BIG5 |
Q7DB77 | TIR_ECO57 | Secreted effector protein Tir | Escherichia | <M><P><I><G><N><L><G><H><N><P><N><V><N><N><S><I><P><P><A><P><P><L><P><S><Q><T><D><G><A><G><G><R><G><Q><L><I><N><S><T><G><P><L><G><S><R><A><L><F><T><P><V><R><N><S><M><A><D><S><G><D><N><R><A><S><D><V><P><G><L><P><V><N><P><M><R><L><A><A><S><E><I><T><L><N><D><G><F><E><V><L><H><D><H><G><P><L><D><T><L><N><R><Q><I><G><S><S><V... | Multifunctional protein that is required for efficient pedestal formation in host epithelial cells during infection. The extracellular region acts as a receptor for bacterial intimin, allowing the bacterium to attach tightly to the host-cell surface. Simultaneously, the intracellular region initiates a signaling cascad... | Q7DB77 |
A1JTP8 | COBT_YERE8 | N(1)-alpha-phosphoribosyltransferase | Yersinia | <M><Q><T><L><S><S><I><L><R><T><I><A><P><L><D><S><K><A><M><A><R><A><T><T><R><L><D><G><L><L><K><P><Q><G><S><L><G><R><L><E><Q><L><A><I><Q><L><A><G><M><R><G><L><Y><G><H><Q><V><D><R><K><Q><I><I><V><M><A><A><D><H><G><V><Y><D><E><G><V><A><I><S><P><R><V><V><T><M><V><Q><A><L><N><M><V><R><G><V><T><G><V><C><V><L><A><A><N><A><G><A... | Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).<BOP> | A1JTP8 |
Q99417 | MYCBP_HUMAN | Associate of Myc 1 | Homo | <M><A><H><Y><K><A><A><D><S><K><R><E><Q><F><R><R><Y><L><E><K><S><G><V><L><D><T><L><T><K><V><L><V><A><L><Y><E><E><P><E><K><P><N><S><A><L><D><F><L><K><H><H><L><G><A><A><T><P><E><N><P><E><I><E><L><L><R><L><E><L><A><E><M><K><E><K><Y><E><A><I><V><E><E><N><K><K><L><K><A><K><L><A><Q><Y><E><P><P><Q><E><E><K><R><A><E> | May control the transcriptional activity of MYC. Stimulates the activation of E box-dependent transcription by MYC.<BOP> | Q99417 |
P11755 | HBA1_TADBR | Hemoglobin alpha-1 chain | Tadarida | <V><L><S><P><E><D><K><N><N><V><K><A><A><W><S><K><V><G><G><Q><A><G><D><Y><G><A><E><A><L><E><R><M><F><L><S><F><P><T><T><K><T><Y><F><P><H><F><D><L><S><H><G><S><A><Q><V><K><G><H><G><K><K><V><G><E><A><L><T><T><A><V><N><H><M><D><D><L><P><G><A><L><S><T><L><S><D><L><H><A><Y><K><L><R><V><D><P><V><N><F><K><L><L><S><H><C><L><L><V... | Involved in oxygen transport from the lung to the various peripheral tissues.<BOP> | P11755 |
Q8E927 | PPNP_SHEON | Xanthosine phosphorylase | Shewanella | <M><E><L><I><E><Q><V><A><V><A><K><K><A><N><I><Y><F><E><G><K><V><A><S><R><S><V><F><F><S><D><G><S><K><Q><T><L><G><V><V><L><P><G><E><Y><E><F><S><T><S><Q><G><E><I><M><H><V><T><S><G><S><F><E><V><L><L><P><N><S><S><T><W><Q><A><F><S><E><G><S><Q><F><E><L><A><A><N><V><S><F><K><I><R><N><N><A><I><A><E><Y><C><C><R><Y><L> | Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.<BOP> | Q8E927 |
A6VXF8 | HEMH_MARMS | Protoheme ferro-lyase | Marinomonas | <M><K><N><T><S><D><Y><G><V><L><M><M><N><L><G><T><P><D><A><P><Q><T><P><E><V><R><R><Y><L><R><E><F><L><S><D><S><R><V><V><D><L><N><P><L><I><W><K><P><I><L><N><L><I><I><L><T><I><R><P><P><K><V><A><K><I><Y><Q><Q><V><W><M><D><E><G><S><P><L><L><V><L><S><E><R><L><K><E><K><V><K><E><A><L><S><E><K><K><G><Q><T><V><P><V><E><L><A><M><T... | Catalyzes the ferrous insertion into protoporphyrin IX.<BOP> | A6VXF8 |
B1JV76 | MURD_BURCC | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase | Burkholderia cepacia complex | <M><F><G><D><R><Q><R><P><M><V><L><V><L><G><L><G><E><S><G><L><A><I><A><R><W><C><A><R><H><G><C><R><L><R><I><A><D><T><R><E><A><P><P><N><L><A><A><L><Q><A><E><G><I><D><A><E><F><V><G><G><A><F><T><P><A><L><L><D><G><G><I><E><I><V><G><L><S><P><G><L><S><P><L><E><P><A><L><A><A><L><V><A><A><A><N><E><R><G><V><A><V><W><G><E><L><E><F... | Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).<BOP> | B1JV76 |
Q5P2R7 | COBS_AROAE | Cobalamin-5'-phosphate synthase | Aromatoleum | <M><T><T><M><R><Y><Q><L><E><L><F><F><T><A><L><G><F><F><T><R><L><P><V><P><A><W><V><P><W><S><P><E><R><L><N><H><A><A><R><F><F><P><L><V><G><W><V><V><G><A><I><G><A><A><S><Y><L><A><F><V><Q><L><L><P><P><A><L><A><V><L><L><S><M><A><V><T><I><R><A><T><G><A><F><H><E><D><G><W><A><D><A><C><D><G><L><G><G><G><W><D><R><L><Q><V><L><T><I... | Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.<BOP> | Q5P2R7 |
Q0T8F3 | FIXA_SHIF8 | Protein FixA | Shigella | <M><K><I><I><T><C><Y><K><C><V><P><D><E><Q><D><I><A><V><N><N><A><D><G><S><L><D><F><S><K><A><D><A><K><I><S><Q><Y><D><L><N><A><I><E><A><A><C><Q><L><K><Q><Q><A><A><E><A><Q><V><T><A><L><S><V><G><G><K><A><L><T><N><A><K><G><R><K><D><V><L><S><R><G><P><D><E><L><I><V><V><I><D><D><Q><F><E><Q><A><L><P><Q><Q><T><A><S><A><L><A><A><A... | Required for anaerobic carnitine reduction. May bring reductant to CaiA.<BOP> | Q0T8F3 |
P0AAB4 | UBID_ECOLI | Polyprenyl p-hydroxybenzoate decarboxylase | Escherichia | <M><D><A><M><K><Y><N><D><L><R><D><F><L><T><L><L><E><Q><Q><G><E><L><K><R><I><T><L><P><V><D><P><H><L><E><I><T><E><I><A><D><R><T><L><R><A><G><G><P><A><L><L><F><E><N><P><K><G><Y><S><M><P><V><L><C><N><L><F><G><T><P><K><R><V><A><M><G><M><G><Q><E><D><V><S><A><L><R><E><V><G><K><L><L><A><F><L><K><E><P><E><P><P><K><G><F><R><D><L... | Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.<BOP> | P0AAB4 |
Q1LPX2 | LEU1_CUPMC | Alpha-isopropylmalate synthase | Cupriavidus | <M><S><D><K><L><I><I><F><D><T><T><L><R><D><G><E><Q><S><P><G><A><S><M><T><R><E><E><K><I><R><I><A><R><Q><L><E><R><L><K><V><D><V><I><E><A><G><F><A><A><S><S><N><G><D><F><E><A><I><R><S><I><A><Q><V><V><K><D><S><T><I><C><S><L><A><R><A><N><D><K><D><I><A><R><A><A><E><A><L><K><P><A><N><S><F><R><I><H><T><F><I><A><T><S><A><L><H><M... | Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).<BOP> | Q1LPX2 |
B1YP34 | RIMP_BURA4 | Ribosome maturation factor RimP | Burkholderia cepacia complex | <M><Q><L><T><E><L><I><E><T><T><V><T><G><L><G><Y><E><L><V><D><L><E><R><T><G><R><G><M><L><C><I><Y><I><D><Q><L><A><G><I><S><L><E><D><C><E><K><V><T><R><Q><L><Q><H><V><L><T><V><E><N><I><D><Y><E><R><L><E><V><S><S><P><G><L><D><R><P><L><K><K><L><A><D><F><E><R><F><A><G><S><E><V><S><V><T><L><K><K><P><L><D><G><R><K><T><Y><R><G><I... | Required for maturation of 30S ribosomal subunits.<BOP> | B1YP34 |
C4L427 | HRCA_EXISA | Heat-inducible transcription repressor HrcA | unclassified Exiguobacterium | <M><L><T><D><R><Q><L><L><I><L><R><A><I><I><D><D><Y><I><Q><T><A><Q><P><V><G><S><R><T><L><S><K><R><D><D><L><T><F><S><S><A><T><I><R><N><D><M><A><D><L><E><D><M><G><L><I><E><K><P><H><T><S><A><G><R><I><P><S><E><V><G><Y><R><Y><Y><V><D><H><L><V><E><K><Q><I><I><D><E><R><E><T><G><R><L><E><E><R><L><K><Q><S><S><K><E><S><E><I><L><I... | Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.<BOP> | C4L427 |
P48172 | COX3_ONCMY | Cytochrome c oxidase polypeptide III | Oncorhynchus | <M><A><H><Q><A><H><A><Y><H><M><V><D><P><S><P><W><P><L><T><G><A><I><A><A><L><L><L><T><S><G><T><A><V><W><F><H><F><H><S><L><T><L><L><T><L><G><N><I><L><L><L><L><T><M><Y><Q><W><W><R><D><I><I><R><E><G><T><F><Q><G><H><H><T><P><P><V><Q><K><G><L><R><Y><G><M><I><L><F><I><T><S><E><V><F><F><F><L><G><F><F><W><A><F><Y><H><A><S><L><A... | Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CII... | P48172 |
A1JIF2 | UBIE_YERE8 | Demethylmenaquinone methyltransferase | Yersinia | <M><V><D><Q><E><K><E><T><T><H><F><G><F><R><T><V><A><K><E><Q><K><E><G><M><V><A><E><V><F><H><S><V><A><A><K><Y><D><L><M><N><D><L><M><S><F><G><V><H><R><I><W><K><R><F><T><I><D><C><S><G><V><R><R><G><Q><R><V><L><D><L><A><G><G><T><G><D><L><T><A><K><F><S><R><L><V><G><E><Q><G><E><V><V><L><A><D><I><N><E><S><M><L><R><M><G><R><E><K... | Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).<BOP> | A1JIF2 |
Q0S424 | MSHB_RHOJR | N-acetyl-1-D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase | Rhodococcus | <M><S><E><R><R><L><L><L><V><H><A><H><P><D><D><E><T><L><T><T><G><G><T><I><A><R><Y><A><A><D><G><A><D><V><H><V><L><T><C><T><L><G><E><E><G><E><V><I><G><E><E><W><A><Q><L><V><A><D><A><A><D><Q><L><G><G><F><R><I><G><E><L><T><S><A><L><S><C><L><G><A><G><R><P><R><F><L><L><G><A><G><H><F><R><D><S><G><M><A><G><T><A><S><A><A><D><P><R... | Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.<BOP> | Q0S424 |
A9M1D3 | RIMP_NEIM0 | Ribosome maturation factor RimP | Neisseria | <M><D><I><Q><T><I><L><E><K><T><L><P><G><L><G><Y><E><L><V><D><F><E><L><T><A><Q><G><T><L><R><V><F><I><D><K><E><G><G><I><T><V><E><D><C><A><T><V><S><N><H><L><S><R><V><F><M><V><E><D><I><D><Y><K><N><L><E><I><S><S><P><G><L><D><R><P><L><K><K><A><A><D><F><V><R><F><A><G><Q><N><A><K><I><K><T><R><L><P><I><D><G><Q><K><N><F><I><G><K... | Required for maturation of 30S ribosomal subunits.<BOP> | A9M1D3 |
Q89L50 | SSB_BRADU | Single-stranded DNA-binding protein | Bradyrhizobium | <M><A><G><S><V><N><K><V><I><L><V><G><N><L><G><K><D><P><E><I><R><R><T><Q><D><G><R><P><I><A><N><L><S><I><A><T><S><E><T><W><R><D><K><N><S><G><E><R><K><E><K><T><E><W><H><R><V><V><I><F><N><E><G><L><C><K><V><A><E><Q><Y><L><K><K><G><A><K><V><Y><I><E><G><A><L><Q><T><R><K><W><T><D><Q><S><G><V><E><K><Y><S><T><E><V><V><L><Q><G><F... | Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.<BOP> | Q89L50 |
Q5LJ16 | KDUI_BACFN | DKI isomerase | Bacteroides | <M><K><T><N><Y><E><I><R><Y><A><A><H><P><E><D><A><R><S><Y><D><T><K><R><I><R><R><D><F><L><I><E><K><V><F><S><A><D><E><V><N><M><V><Y><S><M><Y><D><R><M><V><V><G><G><A><M><P><V><K><E><V><L><K><L><E><A><I><D><P><L><K><A><P><Y><F><L><T><R><R><E><M><G><I><F><N><V><G><G><P><G><V><V><R><A><G><D><A><I><F><Q><L><D><Y><K><E><A><L><Y... | Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.<BOP> | Q5LJ16 |
Q3Z5Y0 | RIHC_SHISS | Purine/pyrimidine ribonucleoside hydrolase | Shigella | <M><R><L><P><I><F><L><D><T><D><P><G><I><D><D><A><V><A><I><A><A><A><I><F><A><P><E><L><D><L><Q><L><M><T><T><V><A><G><N><V><S><V><E><K><T><T><R><N><A><L><Q><L><L><H><F><W><N><A><E><I><P><L><A><Q><G><A><A><V><P><L><V><R><A><P><R><D><A><A><S><V><H><G><E><S><G><M><A><G><Y><D><F><V><E><H><N><R><K><P><I><G><I><P><A><F><L><A><I... | Hydrolyzes both purine and pyrimidine ribonucleosides with a broad-substrate specificity.<BOP> | Q3Z5Y0 |
P54249 | ACHA_ERICO | Acetylcholine receptor subunit alpha | Erinaceus | <A><I><F><K><S><Y><C><E><I><I><V><T><H><F><P><F><D><E><Q><N><C><S><M><K><L><G><T><W><T><Y><D><G><S><V><V><A><I><N><P><E><N><D><Q><P><D><L><S><N><F><M><E><S><G><E><W><V><I><K><E><A><R><G><W><K><H><R><V><I><Y><A><C><C><P><S><T><P><Y><L><D><I><T><Y><H><F> | Upon acetylcholine binding, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.<BOP> | P54249 |
Q1MSA2 | EFP_LAWIP | Elongation factor P | Lawsonia | <M><Y><S><T><T><D><F><R><K><G><L><K><I><E><I><D><G><V><P><Y><D><I><I><D><F><Q><H><F><K><P><G><K><G><G><A><M><V><R><T><K><L><R><N><I><L><N><G><R><V><I><D><N><T><F><R><S><G><E><K><V><E><R><P><N><L><E><S><R><D><M><Q><F><L><Y><H><E><G><S><E><L><I><F><M><D><L><T><N><Y><E><Q><L><H><M><S><E><D><V><T><N><G><K><S><E><F><L><K><D... | Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.<BOP> | Q1MSA2 |
Q72EQ3 | FLGI_DESVH | Basal body P-ring protein | Desulfovibrio | <M><W><P><L><L><L><A><V><A><L><S><T><L><L><P><L><A><M><P><G><S><A><G><A><V><R><I><K><D><I><A><T><F><S><G><V><R><D><N><Q><L><V><G><Y><G><L><V><V><G><L><G><G><T><G><D><K><K><E><S><V><F><T><V><S><S><M><V><N><M><L><E><R><M><G><V><A><V><D><P><K><Q><L><K><P><K><N><V><A><S><V><M><V><T><A><R><M><P><V><S><A><K><P><G><A><R><L><D... | Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.<BOP> | Q72EQ3 |
P14259 | HBA1_OTOCR | Hemoglobin alpha-A chain | Otolemur | <M><V><L><S><P><T><D><K><S><I><V><K><A><A><W><E><K><V><G><A><H><A><G><D><Y><G><A><E><A><L><E><R><M><F><L><S><F><P><T><T><K><T><Y><F><P><Q><F><D><L><S><H><G><S><A><Q><V><K><G><H><G><K><K><V><A><D><A><L><T><N><A><V><L><H><V><D><D><M><P><S><A><L><S><A><L><S><D><L><H><A><H><K><L><T><V><D><P><V><N><F><K><L><L><S><H><C><L><L... | Involved in oxygen transport from the lung to the various peripheral tissues.<BOP> | P14259 |
P16013 | CYF_SPIOL | Cytochrome f | Spinacia | <M><Q><T><I><N><T><F><S><W><I><K><E><Q><I><T><R><S><I><S><I><S><L><I><L><Y><I><I><T><R><S><S><I><A><N><A><Y><P><I><F><A><Q><Q><G><Y><E><N><P><R><E><A><T><G><R><I><V><C><A><N><C><H><L><A><N><K><P><V><D><I><E><V><P><Q><A><V><L><P><D><T><V><F><E><A><V><V><R><I><P><Y><D><M><Q><L><K><Q><V><L><A><N><G><K><K><G><G><L><N><V><G... | Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.<BOP> | P16013 |
P0C0A4 | TMCAL_BACCR | tRNA(Met) cytidine acetate ligase | Bacillus cereus group | <M><Q><Q><T><K><K><L><T><Q><S><D><I><I><I><A><V><M><S><G><P><F><L><Q><R><G><E><P><A><L><I><S><K><W><Y><R><T><K><M><A><L><A><N><G><V><D><L><V><V><E><L><P><Y><V><F><A><T><Q><K><A><E><T><F><A><N><G><A><I><S><I><L><N><A><L><R><V><S><E><I><C><F><G><S><E><D><G><Q><I><E><N><F><Y><N><T><I><S><I><Q><K><N><E><E><E><T><F><N><C><L... | Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.<BOP> | P0C0A4 |
Q0ARD7 | PDXH_MARMM | Pyridoxal 5'-phosphate synthase | Maricaulis | <M><S><D><D><K><L><I><P><A><T><P><D><A><D><A><Y><A><K><T><A><D><A><N><A><A><E><I><F><D><R><D><E><P><F><A><L><F><A><D><W><L><T><E><A><K><K><K><E><P><N><D><A><N><A><M><A><L><A><T><A><D><A><S><G><L><P><D><V><R><M><V><L><L><K><D><V><D><A><D><G><F><V><F><Y><T><N><L><E><S><G><K><G><G><Q><L><A><D><N><P><Q><A><A><L><C><F><H><W... | Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).<BOP> | Q0ARD7 |
A6L5I2 | SYP_PHOV8 | Prolyl-tRNA synthetase | Phocaeicola | <M><A><V><E><L><K><E><L><T><K><R><S><E><N><Y><S><Q><W><Y><N><D><L><V><V><K><A><D><L><A><E><Q><S><P><V><R><G><C><M><V><I><K><P><Y><G><Y><A><I><W><E><K><M><Q><R><Q><L><D><D><M><F><K><E><T><G><H><V><N><A><Y><F><P><L><L><I><P><K><S><Y><L><S><R><E><A><E><H><V><E><G><F><A><K><E><C><A><V><V><T><H><Y><R><L><K><N><A><E><D><G><S... | Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).<BOP> | A6L5I2 |
Q4JUX6 | DDL_CORJK | D-alanylalanine synthetase | Corynebacterium | <M><S><N><E><A><K><K><H><A><R><T><T><V><A><V><L><Y><G><G><Q><S><T><E><H><S><V><S><C><I><S><A><G><A><V><I><D><H><L><D><P><E><I><Y><E><V><V><P><V><G><I><T><E><A><G><A><W><V><P><G><T><T><D><T><S><R><L><R><A><D><G><R><D><M><P><R><V><E><D><G><G><V><H><V><Q><L><T><F><G><G><A><G><T><A><G><S><A><G><S><G><A><A><G><E><M><R><Y><V... | Cell wall formation.<BOP> | Q4JUX6 |
A5WFC8 | RUVA_PSYWF | Holliday junction ATP-dependent DNA helicase RuvA | Psychrobacter | <M><I><G><L><I><E><G><R><V><C><H><L><S><A><P><V><A><C><L><M><T><A><S><G><V><G><Y><E><V><E><L><P><L><P><D><F><C><Q><L><Q><L><E><A><M><A><S><L><W><T><H><L><H><V><R><E><D><A><Q><L><L><Y><G><F><L><H><P><T><E><R><D><V><F><R><Q><L><I><R><V><N><G><V><G><A><K><M><A><L><A><M><M><S><T><F><S><A><T><E><L><K><H><C><I><D><T><E><N><D... | The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA... | A5WFC8 |
A8WHR0 | DCA17_DANRE | DDB1- and CUL4-associated factor 17 | Danio | <M><C><A><L><P><S><P><R><A><Q><R><P><P><A><C><T><R><T><S><K><N><S><C><A><L><L><A><S><R><Y><N><G><S><C><S><N><D><F><G><R><L><L><A><S><N><L><K><I><L><R><N><I><I><L><K><D><D><T><E><F><V><K><V><W><S><K><T><S><K><S><L><I><S><Y><E><S><G><R><I><Y><F><D><N><Y><R><C><C><Y><S><S><L><L><P><E><P><E><L><L><Y><E><L><P><R><T><P><K><T... | May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.<BOP> | A8WHR0 |
C1KVB9 | DNAJ_LISMC | Chaperone protein DnaJ | Listeria | <M><A><K><R><D><Y><Y><E><V><L><G><V><S><K><S><A><S><A><D><E><I><K><K><A><Y><R><K><L><S><K><Q><Y><H><P><D><I><N><K><E><A><G><A><D><E><K><F><K><E><I><S><E><A><Y><E><A><L><S><D><P><Q><K><R><A><Q><Y><D><Q><Y><G><H><V><D><P><N><Q><G><F><G><G><G><A><G><G><G><F><S><G><G><G><F><S><G><F><E><D><I><F><D><T><F><F><G><G><G><G><R><Q... | Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bou... | C1KVB9 |
Q31C25 | SYP_PROM9 | Prolyl-tRNA synthetase | Prochlorococcus | <M><R><V><T><T><S><F><P><L><G><T><L><R><D><T><P><S><E><A><E><I><I><S><H><Q><L><L><L><K><A><G><Y><I><R><R><V><Y><S><G><I><Y><A><Y><M><P><I><M><L><K><V><I><E><K><I><S><K><I><I><E><I><E><L><N><S><I><G><C><T><K><L><L><L><P><Q><L><H><P><A><N><L><W><K><K><S><E><R><W><E><G><Y><T><A><G><E><G><I><M><F><N><L><K><D><R><Q><G><K><E... | Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two addit... | Q31C25 |
P06237 | NOH4_RHIML | Host-specificity of nodulation protein D | Sinorhizobium | <M><T><H><S><T><L><P><P><R><P><F><A><I><L><A><M><R><R><T><G><T><H><Y><L><E><E><L><V><N><E><H><P><N><V><L><S><N><G><E><L><L><N><T><Y><D><T><N><W><P><D><K><E><R><L><L><L><S><D><R><E><L><L><E><R><A><C><W><R><Y><P><P><H><S><D><K><K><V><T><H><V><G><C><K><I><N><E><P><Q><F><Q><E><R><P><S><F><F><A><E><L><T><A><W><P><G><L><K><V... | Required for the formation of sulfated nod factor. Proposed to transfer activated sulfate (PAPS) to a N-acetylglucosamine of the nod factor.<BOP> | P06237 |
A0QQL0 | THIG_MYCS2 | Thiazole synthase | Mycolicibacterium | <M><A><D><S><V><L><R><I><G><G><R><E><F><G><S><R><L><I><M><G><T><G><G><A><P><N><L><S><V><L><E><E><A><L><I><A><S><G><T><E><L><T><T><V><A><M><R><R><V><D><A><E><T><G><T><G><V><L><D><L><L><N><R><L><G><I><A><A><L><P><N><T><A><G><C><R><G><A><A><E><A><V><L><T><A><Q><L><A><R><E><A><L><G><T><D><M><V><K><L><E><V><I><A><D><E><R><T... | Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.<BOP> | A0QQL0 |
Q7MAX2 | RNPH_PHOLL | tRNA nucleotidyltransferase | Photorhabdus | <M><R><P><T><G><R><A><A><E><Q><V><R><P><I><T><I><T><R><H><Y><T><K><H><A><E><G><S><V><L><V><E><F><G><D><T><K><V><L><C><N><A><S><V><E><E><G><V><P><R><F><L><K><G><Q><G><Q><G><W><V><T><A><E><Y><G><M><L><P><R><S><T><H><T><R><N><A><R><E><A><A><R><G><K><Q><G><G><R><T><M><E><I><Q><R><L><I><A><R><S><L><R><A><A><V><D><L><K><K><L... | Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably p... | Q7MAX2 |
Q66JG3 | SYEM_XENTR | Glutamyl-tRNA synthetase | Silurana | <M><R><P><A><F><I><R><G><K><W><L><S><R><T><L><E><L><A><T><G><L><G><R><R><T><C><S><S><R><E><S><G><R><E><V><R><V><R><F><A><P><S><P><T><G><F><L><H><L><G><G><L><R><T><A><L><Y><N><Y><L><F><A><K><K><H><G><G><A><F><I><L><R><L><E><D><T><D><R><S><R><L><V><P><G><A><A><E><S><I><E><D><M><L><E><W><A><G><I><P><P><D><E><S><P><R><H><G... | Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).<BOP> | Q66JG3 |
O95256 | I18RA_HUMAN | Interleukin-18 receptor beta | Homo | <M><L><C><L><G><W><I><F><L><W><L><V><A><G><E><R><I><K><G><F><N><I><S><G><C><S><T><K><K><L><L><W><T><Y><S><T><R><S><E><E><E><F><V><L><F><C><D><L><P><E><P><Q><K><S><H><F><C><H><R><N><R><L><S><P><K><Q><V><P><E><H><L><P><F><M><G><S><N><D><L><S><D><V><Q><W><Y><Q><Q><P><S><N><G><D><P><L><E><D><I><R><K><S><Y><P><H><I><I><Q><D... | Within the IL18 receptor complex, does not mediate IL18-binding, but involved in IL18-dependent signal transduction, leading to NF-kappa-B and JNK activation . May play a role in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells (Probable).<BOP> | O95256 |
B2IHY4 | ILVC_BEII9 | Ketol-acid reductoisomerase type I | Beijerinckia | <M><R><V><Y><Y><D><R><D><A><D><I><N><L><V><K><G><K><K><V><A><I><I><G><Y><G><S><Q><G><H><A><H><A><L><N><L><R><D><S><G><V><K><E><I><A><I><A><L><R><E><G><S><S><T><A><K><K><A><E><A><E><G><L><T><V><K><T><V><V><D><A><A><Q><W><A><D><V><V><M><V><L><T><P><D><E><L><Q><A><D><I><Y><H><Q><L><L><A><K><N><L><K><Q><G><A><A><L><L><F><A... | Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobu... | B2IHY4 |
Q92GC9 | KGUA_RICCN | GMP kinase | spotted fever group | <M><T><T><K><N><K><R><V><L><Q><K><C><A><Y><R><E><E><F><K><G><D><M><E><R><S><T><A><A><T><S><K><L><P><L><E><V><E><L><S><R><N><S><K><G><L><I><I><I><L><S><S><P><S><G><T><G><K><S><S><L><A><K><A><L><L><K><I><D><N><N><L><R><L><S><I><S><A><T><T><R><K><P><R><L><G><E><V><E><G><I><N><Y><Y><F><K><T><G><L><E><F><E><E><L><V><K><Q><N... | Essential for recycling GMP and indirectly, cGMP.<BOP> | Q92GC9 |
Q9S9N1 | HSP7E_ARATH | Heat shock protein 70b | Arabidopsis | <M><A><T><K><S><E><K><A><I><G><I><D><L><G><T><T><Y><S><C><V><G><V><W><M><N><D><R><V><E><I><I><P><N><D><Q><G><N><R><T><T><P><S><Y><V><A><F><T><D><T><E><R><L><I><G><D><A><A><K><N><Q><V><A><L><N><P><Q><N><T><V><F><D><A><K><R><L><I><G><R><K><F><S><D><P><S><V><Q><S><D><I><L><H><W><P><F><K><V><V><S><G><P><G><E><K><P><M><I><V... | In cooperation with other chaperones, Hsp70s are key components that facilitate folding of de novo synthesized proteins, assist translocation of precursor proteins into organelles, and are responsible for degradation of damaged protein under stress conditions.<BOP> | Q9S9N1 |
Q9CWE6 | OOEP_MOUSE | STAT3 downstream gene and differentiation regulator | Mus | <M><A><S><H><T><A><D><A><D><A><K><P><D><S><D><S><Q><K><L><L><N><V><L><P><V><S><L><R><L><R><T><R><P><W><W><F><P><I><Q><E><V><S><N><P><L><V><L><Y><M><E><A><W><V><A><E><R><V><I><G><T><D><Q><A><E><I><S><E><I><E><W><M><C><Q><A><L><L><T><V><D><S><V><N><S><G><N><L><A><E><I><T><I><F><G><Q><P><S><A><Q><T><R><M><K><N><I><L><L><N... | As part of the OOEP-KHDC3 scaffold, recruits BLM and TRIM25 to DNA replication forks, thereby promoting the ubiquitination of BLM by TRIM25, enhancing BLM retainment at replication forks and therefore promoting stalled replication fork restart . Positively regulates the homologous recombination-mediated DNA double-stra... | Q9CWE6 |
B0R8C8 | EF2_HALS3 | Elongation factor 2 | Halobacterium | <M><G><R><R><K><K><I><V><E><Q><C><E><R><L><M><D><N><P><E><Q><I><R><N><I><A><I><A><A><H><V><D><H><G><K><T><T><L><T><D><N><L><L><A><G><A><G><M><I><S><E><D><T><A><G><Q><Q><L><A><M><D><T><E><E><D><E><Q><E><R><G><I><T><I><D><A><A><N><V><S><M><T><H><E><Y><E><G><D><D><H><L><I><N><L><I><D><T><P><G><H><V><D><F><G><G><D><V><T><R... | Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respective... | B0R8C8 |
P0CM83 | COQ4_CRYNB | Coenzyme Q biosynthesis protein 4 | Cryptococcus neoformans species complex | <M><T><L><A><I><P><L><E><L><S><L><F><D><P><T><S><A><D><F><L><V><P><L><I><S><F><S><A><Y><F><S><V><K><S><F><T><M><R><P><C><P><R><L><L><T><R><K><L><N><Y><P><G><H><I><P><L><S><P><A><Q><N><A><L><L><A><V><G><S><G><V><V><G><V><L><D><V><T><R><G><D><L><I><A><S><L><S><E><S><T><A><G><I><F><L><P><A><L><H><E><K><M><K><M><T><P><E><G... | Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides.<BOP> | P0CM83 |
B1YQ56 | GCS2_BURA4 | Gamma-glutamylcysteine synthetase 2 | Burkholderia cepacia complex | <M><A><L><E><T><F><V><N><S><E><P><F><T><F><G><V><E><L><E><I><Q><V><V><N><T><H><N><Y><D><L><T><K><A><A><S><D><L><M><R><L><I><Q><G><E><T><F><P><G><N><I><T><P><E><I><T><E><S><M><I><E><L><S><T><G><I><C><H><S><H><E><Q><A><V><S><E><L><H><A><I><R><D><V><L><V><K><A><A><D><Q><L><N><V><G><L><C><G><G><G><T><H><A><F><Q><Q><W><S><D... | ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.<BOP> | B1YQ56 |
Q8EIX5 | BFE_SHEON | Bacterial flavin adenine dinucleotide exporter | Shewanella | <M><K><D><R><H><G><L><L><S><A><P><I><G><R><V><L><L><N><M><S><L><P><N><L><I><G><I><M><T><I><L><G><F><S><L><A><D><T><F><F><I><S><Q><L><G><T><E><A><L><A><A><I><S><F><T><F><P><V><T><L><I><I><S><S><I><A><I><G><V><G><A><G><V><S><T><N><L><G><R><L><I><G><S><G><N><A><P><Q><A><K><V><F><L><H><D><A><L><L><L><T><F><I><L><I><A><S><L... | Flavin adenine dinucleotide (FAD) transporter that facilitates export of flavin electron shuttles.<BOP> | Q8EIX5 |
Q9ZSA2 | CDPKL_ARATH | Calcium-dependent protein kinase 21 | Arabidopsis | <M><G><C><F><S><S><K><H><R><K><T><Q><N><D><G><G><E><K><S><I><P><I><N><P><V><Q><T><H><V><V><P><E><H><R><K><P><Q><T><P><T><P><K><P><M><T><Q><P><I><H><Q><Q><I><S><T><P><S><S><N><P><V><S><V><R><D><P><D><T><I><L><G><K><P><F><E><D><I><R><K><F><Y><S><L><G><K><E><L><G><R><G><Q><F><G><I><T><Y><M><C><K><E><I><G><T><G><N><T><Y><A... | May play a role in signal transduction pathways that involve calcium as a second messenger. Mediates the phosphorylation and activation of the S-type anion efflux channel SLAC1.<BOP> | Q9ZSA2 |
Q2SXU7 | FABH_BURTA | 3-oxoacyl-[acyl-carrier-protein] synthase III | pseudomallei group | <M><A><Q><S><T><L><Y><S><R><V><L><G><T><G><S><Y><L><P><P><D><R><V><T><N><Q><E><L><A><D><R><L><A><K><D><G><I><E><T><S><D><E><W><I><V><A><R><T><G><I><H><A><R><H><F><A><A><P><D><V><T><T><S><D><L><A><F><V><A><A><Q><R><A><I><E><A><A><D><V><D><P><Q><S><I><D><L><I><I><V><A><T><S><T><P><D><F><V><F><P><S><T><A><C><L><L><Q><N><K... | Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-A... | Q2SXU7 |
P42473 | EFTU_CHLP8 | Elongation factor Tu | Chlorobaculum | <M><A><K><E><S><Y><K><R><D><K><P><H><V><N><I><G><T><I><G><H><V><D><H><G><K><T><T><L><T><A><A><I><T><S><V><L><A><K><S><G><K><A><A><A><R><E><F><G><D><I><D><K><A><P><E><E><R><E><R><G><I><T><I><S><T><A><H><V><E><Y><Q><T><D><K><R><H><Y><A><H><I><D><C><P><G><H><A><D><Y><I><K><N><M><I><T><G><A><A><Q><M><D><G><A><I><L><V><V><A... | This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.<BOP> | P42473 |
A0KNY4 | FIS_AERHH | DNA-binding protein Fis | Aeromonas | <M><F><E><Q><T><L><T><S><D><A><L><V><T><T><T><H><N><H><A><A><E><P><T><Q><R><P><L><R><D><S><V><Q><Q><A><L><R><N><Y><L><A><Q><L><N><G><Q><E><V><I><D><L><Y><D><M><V><L><S><E><V><E><A><P><M><L><D><V><I><M><Q><Y><T><R><G><N><Q><T><R><A><A><V><M><M><G><I><N><R><G><T><L><R><K><K><L><K><R><Y><G><M><N> | Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters.<BOP> | A0KNY4 |
A4SM13 | AROA_AERS4 | 5-enolpyruvylshikimate-3-phosphate synthase | Aeromonas | <M><N><S><L><R><L><E><P><I><S><R><V><A><G><E><V><N><L><P><G><S><K><S><V><S><N><R><A><L><L><L><A><A><L><A><R><G><T><T><R><L><T><N><L><L><D><S><D><D><I><R><H><M><L><A><A><L><T><Q><L><G><V><K><Y><K><L><S><A><D><K><T><E><C><T><V><H><G><L><G><R><S><F><A><V><S><A><P><V><N><L><F><L><G><N><A><G><T><A><M><R><P><L><C><A><A><L><C... | Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.<BOP> | A4SM13 |
A3Q9T4 | UBID_SHELP | Polyprenyl p-hydroxybenzoate decarboxylase | Shewanella | <M><S><F><K><D><L><R><S><F><I><D><H><L><E><A><N><G><E><L><K><R><I><A><H><P><V><D><P><H><L><E><M><T><E><I><A><D><R><V><L><R><A><K><G><P><A><L><L><F><E><N><P><V><G><K><T><M><P><V><L><A><N><L><F><G><T><P><K><R><V><A><M><A><L><G><K><E><D><P><L><A><L><R><D><V><G><E><L><L><A><F><L><K><E><P><E><P><P><R><G><F><K><D><A><I><S><K... | Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.<BOP> | A3Q9T4 |
C1A2Y4 | GREA_RHOE4 | Transcript cleavage factor GreA | Rhodococcus erythropolis group | <M><T><E><T><Q><V><T><W><L><T><Q><E><S><H><D><R><L><K><N><E><L><D><Q><L><I><A><N><R><P><V><I><A><A><E><I><N><E><R><R><E><E><G><D><L><K><E><N><G><G><Y><H><A><A><R><E><E><Q><G><Q><Q><E><A><R><I><R><Q><L><Q><E><L><L><N><S><A><K><V><G><E><A><P><T><Q><S><G><V><A><L><P><G><S><V><V><K><V><Y><Y><D><G><D><E><S><D><T><E><T><F><L... | Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factor... | C1A2Y4 |
G5ED47 | HIZR1_CAEEL | Nuclear hormone receptor family member nhr-33 | Caenorhabditis | <M><Q><K><V><M><N><D><P><E><D><L><G><N><C><K><I><C><L><Q><R><A><D><G><I><H><F><A><V><S><S><C><R><A><C><A><A><F><F><R><R><T><V><I><L><K><L><N><Y><T><C><K><E><K><G><N><C><T><V><E><K><S><L><R><N><L><C><R><S><C><R><Y><T><R><C><I><N><E><G><M><K><I><E><L><V><Q><L><Q><R><D><S><I><G><R><K><K><S><G><A><S><I><S><I><D><P><L><F><T... | Nuclear receptor transcription factor that binds to DNA enhancer elements to promote the transcription of genes required to maintain micronutrient homeostasis. Direct binding to its ligand zinc allows for nuclear accumulation and activation, which thereby induces the transcription of genes required to promote the stora... | G5ED47 |
Q0ST54 | CLPX_CLOPS | ATP-dependent Clp protease ATP-binding subunit ClpX | Clostridium | <M><G><K><F><E><D><K><K><Q><L><R><C><S><F><C><G><K><N><Q><E><Q><V><K><R><L><I><A><G><P><G><V><Y><I><C><D><E><C><I><E><L><C><S><E><I><I><E><D><E><F><E><G><N><T><E><S><S><P><L><E><T><S><N><L><P><K><P><Q><E><I><K><D><Y><L><D><Q><Y><V><V><G><Q><D><R><A><K><K><S><L><A><V><A><V><Y><N><H><Y><K><R><I><N><A><N><K><A><E><D><D><V... | ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.<BOP> | Q0ST54 |
Q1GF14 | MRAY_RUEST | UDP-MurNAc-pentapeptide phosphotransferase | unclassified Ruegeria | <M><L><Y><W><L><T><A><L><S><D><G><G><D><F><F><N><L><F><R><Y><I><T><F><R><A><G><G><A><F><L><T><A><L><I><F><G><F><V><F><G><K><P><L><I><N><V><L><R><K><R><Q><G><K><G><Q><P><I><R><D><D><G><P><E><A><H><L><A><K><V><G><T><P><T><M><G><G><L><L><I><V><G><A><L><L><F><S><T><L><M><W><A><R><W><D><N><P><F><V><W><L><V><L><F><V><T><M><S... | Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I... | Q1GF14 |
Q5WB79 | ATPE_ALKCK | F-ATPase epsilon subunit | Alkalihalobacillus | <M><A><T><I><Q><V><S><V><I><T><P><D><G><A><V><Y><E><G><D><A><E><L><V><V><V><K><T><V><E><G><E><L><G><I><K><A><K><H><I><P><L><V><S><P><L><A><V><G><P><A><R><F><I><K><E><G><K><E><E><Q><V><A><V><S><S><G><F><V><E><V><R><P><D><H><V><S><I><L><A><E><A><A><E><R><P><E><Q><I><D><T><E><R><A><R><K><A><K><E><R><A><E><Q><R><L><A><S><E... | Produces ATP from ADP in the presence of a proton gradient across the membrane.<BOP> | Q5WB79 |
Q6F799 | HIS6_ACIAD | ImGP synthase subunit HisF | Acinetobacter | <M><L><A><K><R><I><I><P><C><L><D><V><D><N><G><R><V><V><K><G><V><Q><F><L><D><I><R><D><A><G><D><P><V><E><V><A><R><R><Y><N><E><Q><G><A><D><E><I><T><F><L><D><I><T><A><T><H><H><G><R><D><T><T><Y><R><T><V><E><R><M><A><E><S><V><F><V><P><L><T><V><G><G><G><V><R><K><V><E><D><I><R><L><L><L><N><A><G><A><D><K><V><S><I><N><S><A><A><V... | IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.<BOP> | Q6F799 |
Q8DVV4 | EFG_STRMU | Elongation factor G | Streptococcus | <M><A><R><E><F><S><L><E><K><T><R><N><I><G><I><M><A><H><V><D><A><G><K><T><T><T><T><E><R><I><L><Y><Y><T><G><K><I><H><K><I><G><E><T><H><E><G><A><S><Q><M><D><W><M><E><Q><E><Q><E><R><G><I><T><I><T><S><A><A><T><T><A><Q><W><K><D><H><R><V><N><I><I><D><T><P><G><H><V><D><F><T><I><E><V><Q><R><S><L><R><V><L><D><G><A><V><T><V><L><D... | Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respective... | Q8DVV4 |
Q5ZKE7 | KCY_CHICK | Uridine monophosphate/cytidine monophosphate kinase | Gallus | <M><K><P><V><V><V><F><V><L><G><G><P><G><A><G><K><G><T><Q><C><A><R><I><V><E><K><Y><G><Y><T><H><L><S><A><G><D><L><L><R><D><E><R><K><R><P><G><S><Q><Y><G><E><L><I><E><N><Y><I><K><E><G><E><I><V><P><V><E><I><T><I><S><L><L><K><R><A><M><D><Q><T><M><A><A><N><S><Q><K><N><K><F><L><I><D><G><F><P><R><N><E><D><N><L><Q><G><W><N><K><T... | Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity.<BOP> | Q5ZKE7 |
A0A060XQP6 | OMM64_ONCMY | Otolith matrix macromolecule-64 | Oncorhynchus | <M><L><S><R><L><L><I><V><P><L><I><F><A><L><A><G><L><A><I><S><A><P><V><N><D><G><T><E><A><D><N><D><E><R><A><A><S><L><L><V><H><L><K><G><D><K><D><G><G><G><L><T><G><S><P><D><G><V><S><A><G><T><T><D><G><T><D><S><S><K><E><L><A><G><G><A><V><D><S><S><P><D><T><T><D><T><P><D><A><S><S><S><D><I><F><P><D><T><N><N><R><D><T><S><V><E><T... | Calcium-binding component of otoliths, a calcium carbonate structure of the inner ear involved in hearing and balance sensing . Binds calcium .<BOP> | A0A060XQP6 |
C8VEJ5 | NPTA_EMENI | Nidulanin A prenyltransferase | Aspergillus subgen. Nidulantes | <M><V><A><T><P><D><D><P><R><A><Q><T><I><V><D><L><F><N><G><Q><G><S><A><P><A><P><F><D><V><L><T><S><A><L><S><F><P><T><R><D><Q><E><Q><W><W><R><K><T><G><P><M><F><G><Q><M><L><A><S><S><G><Y><T><L><D><Q><Q><Y><R><H><L><T><F><Y><Y><N><Q><L><V><P><R><L><G><P><H><P><A><T><F><H><S><S><L><T><V><S><G><L><P><M><E><F><S><I><N><Y><Q><Q... | Nonribosomal peptide synthase involved in the synthesis of nidulanin A and derived compounds . Nidulanin A is a tetracyclopeptide with the sequence L-Phe-L-Kyn-L-Val-D-Val and an isoprene unit N-linked to the amino group of L-kynurenine . The NRPS nlsA is responsible of the synthesis of the cyclopeptide and the prenylt... | C8VEJ5 |
A4X148 | DNAK_SALTO | Heat shock protein 70 | Salinispora | <M><A><R><A><V><G><I><D><L><G><T><T><N><S><C><V><S><V><L><E><G><G><E><P><T><V><I><A><N><A><E><G><S><R><T><T><P><S><I><V><A><F><A><R><N><G><E><V><L><V><G><E><V><A><K><R><Q><A><V><T><N><P><D><R><T><I><R><S><V><K><R><E><I><G><T><D><W><F><V><D><I><D><D><K><K><Y><T><P><Q><E><I><S><A><R><T><L><M><K><L><K><R><D><A><E><A><Y><L... | Acts as a chaperone.<BOP> | A4X148 |
Q5DYC3 | RLMF_ALIF1 | rRNA adenine N-6-methyltransferase | Aliivibrio | <M><T><N><T><K><S><N><V><T><K><K><S><L><H><P><R><N><K><H><T><G><N><Y><D><F><P><A><L><I><K><A><C><A><E><L><K><P><F><V><E><T><N><Q><Y><G><N><E><S><I><N><F><S><D><P><Q><A><V><K><A><L><N><K><A><L><L><A><H><F><Y><N><V><P><F><W><D><I><P><Q><G><Y><L><C><P><P><I><P><G><R><A><D><Y><I><H><N><I><A><D><L><L><A><I><T><N><E><G><T><I... | Specifically methylates the adenine in position 1618 of 23S rRNA.<BOP> | Q5DYC3 |
P36196 | ACES_CHICK | Acetylcholinesterase | Gallus | <M><A><P><L><F><L><L><L><L><L><L><L><S><P><S><P><T><S><A><H><R><F><A><Y><S><A><P><N><R><P><E><V><R><T><T><T><G><S><V><R><G><L><L><I><P><A><G><P><S><G><S><T><A><A><A><F><L><G><I><P><F><A><V><P><P><L><G><P><L><R><F><R><P><P><L><P><I><P><T><P><W><T><G><I><R><D><A><D><S><Q><P><F><A><C><Y><Q><M><V><D><T><T><F><P><G><F><Q><G... | Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft.<BOP> | P36196 |
B1I7I7 | PLSX_STRPI | Phosphate-acyl-ACP acyltransferase | Streptococcus | <M><K><K><I><A><V><D><A><M><G><G><D><Y><A><P><Q><A><I><V><E><G><V><N><Q><A><L><S><D><F><S><D><I><E><V><Q><L><Y><G><D><E><A><K><I><K><Q><Y><L><T><A><T><E><R><V><S><I><I><H><T><D><E><K><I><D><S><D><D><E><P><T><R><A><I><R><N><K><K><N><A><S><M><V><L><A><A><K><A><V><K><D><G><E><A><D><A><V><L><S><A><G><N><T><G><A><L><L><A><A... | Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.<BOP> | B1I7I7 |
Q74LF9 | XPT_LACJO | Xanthine phosphoribosyltransferase | Lactobacillus | <M><K><L><L><E><E><R><I><R><K><D><G><E><V><L><D><G><N><V><L><K><I><N><S><F><L><N><H><Q><V><D><P><Q><L><M><M><E><V><G><K><E><F><K><R><L><F><E><N><E><K><I><T><K><V><L><T><C><E><A><S><G><I><A><P><G><I><M><A><A><Y><Q><L><G><V><P><M><V><F><A><R><K><K><K><P><S><T><L><N><D><A><V><Y><W><A><D><V><F><S><Y><T><K><K><V><N><N><K><I... | Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.<BOP> | Q74LF9 |
P28843 | DPP4_MOUSE | Dipeptidyl peptidase IV soluble form | Mus | <M><K><T><P><W><K><V><L><L><G><L><L><G><V><A><A><L><V><T><I><I><T><V><P><I><V><L><L><S><K><D><E><A><A><A><D><S><R><R><T><Y><S><L><A><D><Y><L><K><S><T><F><R><V><K><S><Y><S><L><W><W><V><S><D><F><E><Y><L><Y><K><Q><E><N><N><I><L><L><L><N><A><E><H><G><N><S><S><I><F><L><E><N><S><T><F><E><S><F><G><Y><H><S><V><S><P><D><R><L><F... | Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activat... | P28843 |
Q83H92 | DCUP_TROW8 | Uroporphyrinogen decarboxylase | Tropheryma | <M><T><G><A><S><G><V><E><G><T><R><I><P><L><H><S><L><S><C><R><P><S><A><G><R><S><A><G><S><F><V><N><T><G><I><M><E><A><F><R><G><T><R><P><G><C><L><P><V><W><F><M><R><Q><A><G><R><S><L><P><E><Y><R><A><V><R><G><T><N><T><L><L><E><A><C><L><N><P><D><L><A><C><E><I><T><L><Q><P><V><R><R><Y><S><V><D><A><A><I><L><F><S><D><I><V><V><P><L... | Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.<BOP> | Q83H92 |
Q9ZFF7 | AROA_SHISO | 5-enolpyruvylshikimate-3-phosphate synthase | Shigella | <M><E><S><L><T><L><Q><P><I><A><R><V><D><G><T><I><N><L><P><G><S><K><S><V><S><N><R><A><L><L><L><A><A><L><A><H><G><K><T><V><L><T><N><L><L><D><S><D><D><V><R><H><M><L><N><A><L><T><A><L><G><V><S><Y><T><L><S><A><D><R><T><R><C><E><I><I><G><N><G><G><P><L><H><A><E><G><A><L><E><L><F><L><G><N><A><G><T><A><M><R><P><L><A><A><A><L><C... | Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.<BOP> | Q9ZFF7 |
B8GLD8 | RPPH_THISH | (Di)nucleoside polyphosphate hydrolase | Thioalkalivibrio | <M><I><D><C><D><G><Y><R><P><N><V><G><I><I><L><S><N><Q><E><R><R><L><F><W><A><K><R><I><G><Q><Q><A><W><Q><F><P><Q><G><G><I><R><R><D><E><S><P><L><D><A><M><Y><R><E><L><A><E><E><T><G><L><G><P><E><H><V><E><V><I><G><K><T><R><D><W><L><R><Y><R><L><P><K><H><L><I><R><R><H><S><N><P><V><C><I><G><Q><K><Q><I><W><F><M><L><R><L><V><G><D... | Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.<BOP> | B8GLD8 |
P86160 | BR1VB_RANAR | Brevinin-1AVb | Rana | <F><V><P><L><L><V><S><K><L><V><C><V><V><T><K><K><C> | Antimicrobial peptide.<BOP> | P86160 |
P0CQ85 | HAS1_CRYNB | ATP-dependent RNA helicase HAS1 | Cryptococcus neoformans species complex | <M><E><R><R><D><R><M><R><I><S><T><A><Q><K><F><G><W><G><S><Q><A><Q><T><G><R><R><F><V><L><R><I><F><M><V><I><L><S><L><E><K><L><R><Q><G><S><L><L><C><M><T><P><S><H><G><N><A><H><S><S><A><H><R><A><M><S><S><T><K><P><P><T><T><T><N><K><R><K><R><T><S><N><A><H><D><E><A><P><A><K><R><V><P><E><A><S><S><S><K><V><T><L><D><D><S><Q><P><A... | ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.<BOP> | P0CQ85 |
Q7U4E4 | PSAA_PARMW | PsaA | Parasynechococcus marenigrum | <M><T><I><S><P><P><E><R><G><S><D><A><K><S><Q><V><E><K><V><D><N><P><A><T><F><E><L><F><G><K><P><G><H><F><D><R><A><L><A><K><G><P><K><T><T><S><W><V><W><N><L><H><A><N><A><H><D><F><D><A><H><T><S><D><L><Q><E><V><S><R><R><I><F><S><A><H><F><G><H><L><A><V><I><F><I><W><L><S><G><A><F><F><H><G><A><R><F><S><N><Y><S><G><W><L><A><D><P... | PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spe... | Q7U4E4 |
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