accession
stringlengths
6
10
name
stringlengths
6
11
Full Name
stringlengths
1
147
taxon
stringlengths
3
46
sequence
stringlengths
48
8.26k
function
stringlengths
11
5.52k
AlphaFoldDB
stringlengths
6
10
C9K2Q3
BSC8_ALTBR
Geranylgeranyl diphosphate synthase
Alternaria sect. Brassicicola
<M><K><Y><Q><F><S><I><I><V><D><P><A><T><Y><D><N><E><G><L><S><N><G><I><D><L><R><K><N><N><F><T><H><L><E><D><R><G><A><I><R><A><Q><Q><D><W><A><T><H><I><A><P><I><K><Q><F><K><G><T><L><G><H><D><Y><S><F><M><T><V><C><V><P><E><C><I><P><I><R><L><E><I><I><S><Y><A><N><E><F><A><F><M><Y><D><D><D><T><E><L><D><T><E><N><N><T><S><A><E><N...
Multifunctional diterpene synthase; part of the gene cluster that mediates the biosynthesis of the diterpene glucoside brassicicene C . In the first step of the brassicicene C biosynthesis, the bifunctionnal diterpene synthase bsc8 that possesses both prenyl transferase and terpene cyclase activity, converts isopenteny...
C9K2Q3
Q3Z976
RL22_DEHM1
50S ribosomal protein L22
Dehalococcoides
<M><E><V><K><A><I><V><K><D><T><G><Y><S><A><L><K><V><R><L><C><V><D><M><V><R><G><K><K><V><S><E><A><I><T><M><L><R><F><M><T><S><P><T><A><K><V><V><S><K><V><I><K><S><A><A><A><N><A><E><N><N><F><Q><M><N><P><A><D><L><K><I><S><Q><I><Y><A><D><E><A><R><M><L><K><R><M><R><P><Q><A><R><G><R><V><S><P><I><L><K><R><S><S><H><I><T><V><V><V...
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.<BOP>
Q3Z976
P20944
CD44_CRIGR
Phagocytic glycoprotein I
Cricetulus
<M><D><K><F><W><W><H><A><A><W><G><L><C><L><L><P><L><S><L><A><H><E><Q><I><D><L><N><I><T><C><R><Y><A><G><V><F><H><V><E><K><N><G><R><Y><S><I><S><R><T><E><A><A><D><L><C><Q><A><F><N><S><T><L><P><T><M><D><Q><M><V><M><A><L><S><K><G><F><E><T><C><R><Y><G><F><I><E><G><H><V><V><I><P><R><I><Q><P><N><A><I><C><A><A><N><H><T><G><V><Y...
Cell-surface receptor that plays a role in cell-cell interactions, as well as cell adhesion and migration, helping them to sense and respond to changes in the tissue microenvironment. Participates thereby in a wide variety of cellular functions including the activation, recirculation and homing of T-lymphocytes, hemato...
P20944
P49188
CRF_XENLA
Corticotropin-releasing hormone
Xenopus
<M><K><F><Q><L><W><V><S><T><G><I><L><L><V><S><L><L><P><C><H><E><C><R><A><F><I><K><S><P><A><S><S><P><G><A><L><L><P><A><L><S><N><S><Q><P><F><L><L><R><M><G><E><E><Y><F><L><R><L><G><N><L><H><K><H><S><P><G><S><F><P><E><A><S><A><G><N><F><V><R><A><V><Q><Q><L><Q><A><Q><Q><W><S><S><Q><P><G><M><R><A><A><S><L><D><G><A><D><S><P><Y...
This hormone from hypothalamus regulates the release of corticotropin from pituitary gland.<BOP>
P49188
Q5LPK1
GATB_RUEPO
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B
Ruegeria
<M><L><D><L><T><F><E><T><P><K><P><K><T><I><A><G><A><K><H><D><W><E><L><V><I><G><M><E><V><H><A><Q><V><A><S><Q><A><K><L><F><S><G><A><S><T><A><F><G><A><E><P><N><S><N><V><S><F><V><D><A><A><M><P><G><M><L><P><V><I><N><E><F><C><V><E><Q><A><V><R><T><G><L><G><L><K><A><E><I><N><L><K><S><A><F><D><R><K><N><Y><F><Y><P><D><L><P><Q><G...
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated ...
Q5LPK1
Q46L69
RS15_PROMT
30S ribosomal protein S15
Prochlorococcus
<M><S><L><G><T><E><E><K><Q><N><L><I><N><T><H><Q><V><H><P><T><D><T><G><S><A><E><V><Q><V><A><M><L><T><T><R><I><S><K><L><S><T><H><L><Q><G><N><I><H><D><F><S><S><R><Q><G><L><L><K><M><I><G><Q><R><K><R><L><L><G><Y><V><R><S><K><S><E><K><R><Y><T><E><L><I><E><K><L><A><I><R><G>
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.<BOP>
Q46L69
P11987
MEMG_METCA
Methane hydroxylase
Methylococcus
<M><A><K><L><G><I><H><S><N><D><T><R><D><A><W><V><N><K><I><A><Q><L><N><T><L><E><K><A><A><E><M><L><K><Q><F><R><M><D><H><T><T><P><F><R><N><S><Y><E><L><D><N><D><Y><L><W><I><E><A><K><L><E><E><K><V><A><V><L><K><A><R><A><F><N><E><V><D><F><R><H><K><T><A><F><G><E><D><A><K><S><V><L><D><G><T><V><A><K><M><N><A><A><K><D><K><W><E><A...
Responsible for the initial oxygenation of methane to methanol in methanotrophs. It also catalyzes the monohydroxylation of a variety of unactivated alkenes, alicyclic, aromatic and heterocyclic compounds.<BOP>
P11987
A8F801
PURA_PSELT
null
Pseudothermotoga
<M><L><K><A><A><V><I><G><L><Q><W><G><D><E><G><K><G><K><V><V><T><Y><L><S><R><R><Y><D><C><V><V><R><Y><S><G><G><S><N><A><G><H><T><V><D><Y><G><N><F><K><M><V><H><H><L><L><P><S><A><D><I><K><K><Q><K><M><M><Y><I><G><P><G><V><V><V><D><L><D><V><L><L><E><E><I><D><Q><I><N><N><L><I><P><E><S><R><S><L><L><R><I><S><K><Q><A><H><V><V><I...
Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.<BOP>
A8F801
Q8EPQ8
QUEA_OCEIH
Queuosine biosynthesis protein QueA
Oceanobacillus
<M><Q><I><E><D><F><D><F><H><L><P><E><E><L><I><A><Q><T><P><L><K><D><R><T><S><S><R><L><C><V><L><D><K><Q><T><S><E><I><T><H><R><S><F><K><D><I><T><T><Y><L><Q><A><G><D><C><L><V><L><N><D><T><K><V><L><P><A><R><L><Y><G><V><K><S><D><T><G><A><K><I><E><V><L><L><L><H><Q><Q><E><E><D><T><W><E><V><L><V><K><P><A><K><K><V><K><V><G><T><E...
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).<BOP>
Q8EPQ8
Q557H3
VP35L_DICDI
VPS35 endosomal protein sorting factor-like
Dictyostelium
<M><A><E><R><Q><S><A><S><S><P><T><P><S><S><P><P><Q><Q><Q><Q><Q><T><P><Q><Q><P><P><Q><Y><L><L><N><S><K><K><N><F><K><V><K><V><L><N><G><R><E><V><E><R><H><P><L><N><S><I><T><K><T><E><D><T><G><K><P><K><Q><S><S><L><S><S><N><A><S><S><L><Q><S><A><A><A><A><A><S><S><S><T><A><T><T><D><I><D><P><L><N><N><N><N><N><N><N><T><D><I><D><P...
Acts as component of the retriever complex. The retriever complex is a heterotrimeric complex related to retromer cargo-selective complex (CSC) and essential for retromer-independent retrieval and recycling of numerous cargos.<BOP>
Q557H3
A4YCW6
RL3_METS5
50S ribosomal protein L3
Metallosphaera
<M><G><H><R><K><L><S><S><P><R><R><G><S><A><G><L><R><P><R><K><R><S><E><E><L><L><P><S><P><R><S><Y><P><E><V><N><L><P><N><P><V><T><L><G><F><V><G><Y><K><V><G><M><T><H><I><F><M><I><D><E><D><R><S><S><S><M><F><G><K><E><I><Y><V><P><V><T><V><L><E><T><P><P><I><Y><V><L><A><L><R><A><Y><G><L><N><N><R><G><E><H><S><V><M><G><E><V><W><G...
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.<BOP>
A4YCW6
Q3SH78
GLGB_THIDA
Glycogen branching enzyme
Thiobacillus
<M><R><K><L><V><E><A><T><Q><A><G><S><E><A><S><V><A><L><A><P><S><A><P><I><Q><R><L><Q><A><G><L><H><H><D><P><F><E><V><L><G><V><H><V><Q><P><D><G><S><K><L><V><R><A><F><L><P><A><A><E><A><V><E><V><A><G><V><R><M><T><R><V><P><G><T><D><C><F><E><R><L><L><P><P><G><T><A><L><E><A><H><P><L><L><T><W><Q><D><K><R><S><G><A><W><Q><R><L><R...
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.<BOP>
Q3SH78
Q03ZG8
RECR_LEUMM
Recombination protein RecR
Leuconostoc
<M><Q><Y><P><E><P><I><A><K><L><I><D><S><Y><T><K><L><P><G><I><G><P><K><T><A><T><R><L><A><F><Y><T><L><G><M><N><E><E><D><V><Q><D><F><S><K><A><L><I><S><A><K><T><D><L><T><F><C><S><I><C><G><N><I><T><A><T><D><T><D><P><C><V><I><C><R><D><Q><S><R><D><Q><S><T><V><F><V><V><E><N><S><R><D><V><M><A><M><E><N><T><R><D><Y><H><G><L><Y><H...
May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.<BOP>
Q03ZG8
Q9BXA5
SUCR1_HUMAN
P2Y purinoceptor 1-like
Homo
<M><L><G><I><M><A><W><N><A><T><C><K><N><W><L><A><A><E><A><A><L><E><K><Y><Y><L><S><I><F><Y><G><I><E><F><V><V><G><V><L><G><N><T><I><V><V><Y><G><Y><I><F><S><L><K><N><W><N><S><S><N><I><Y><L><F><N><L><S><V><S><D><L><A><F><L><C><T><L><P><M><L><I><R><S><Y><A><N><G><N><W><I><Y><G><D><V><L><C><I><S><N><R><Y><V><L><H><A><N><L><Y...
Receptor for succinate.<BOP>
Q9BXA5
B3EP06
MDH_CHLPB
Malate dehydrogenase
Chlorobium
<M><K><I><T><V><I><G><A><G><H><V><G><A><T><A><A><H><R><I><A><E><Q><Q><L><A><N><T><V><V><L><F><D><I><L><E><G><I><P><Q><G><K><A><L><D><M><Y><E><S><G><P><V><G><L><F><D><T><K><V><Y><G><T><T><D><Y><N><D><T><A><D><S><D><I><I><L><I><T><A><G><M><A><R><K><P><G><M><S><R><E><D><L><L><M><K><N><A><T><I><V><K><E><V><T><D><Q><V><V><R...
Catalyzes the reversible oxidation of malate to oxaloacetate.<BOP>
B3EP06
A9BPU6
ATPG_DELAS
F-ATPase gamma subunit
Delftia
<M><A><A><G><K><E><I><R><G><K><I><K><S><V><E><N><T><K><K><I><T><K><A><M><E><M><V><A><A><S><K><M><R><K><A><Q><E><R><M><L><A><A><R><P><Y><S><E><K><I><R><N><I><A><V><H><L><G><Q><A><N><P><E><Y><V><H><P><F><M><Q><V><N><G><D><A><K><T><A><G><V><I><V><V><T><T><D><K><G><L><C><G><G><M><N><T><N><V><L><R><A><V><T><A><K><L><R><E><L...
Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.<BOP>
A9BPU6
Q1MIC8
RS14_RHIL3
30S ribosomal protein S14
Rhizobium
<M><A><K><T><S><A><V><E><K><N><K><R><R><R><T><T><V><A><N><Q><A><A><K><R><A><G><L><K><A><I><I><M><N><Q><A><L><P><I><E><E><R><F><K><A><S><I><K><L><A><S><L><P><R><D><G><S><K><T><R><I><R><N><R><C><E><V><S><G><R><P><R><A><Y><Y><R><K><L><R><M><S><R><I><A><L><R><E><L><G><N><L><G><K><V><P><G><I><V><K><S><S><W>
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.<BOP>
Q1MIC8
A4SD60
MEND_CHLPM
Menaquinone biosynthesis protein MenD
Chlorobium
<M><N><N><P><Q><L><T><T><V><W><S><S><V><M><V><E><E><L><I><R><Q><G><A><S><F><F><C><I><S><P><G><S><R><S><T><P><L><T><A><A><I><A><R><N><P><E><A><S><W><K><M><F><P><D><E><R><S><A><G><F><F><A><L><G><H><A><R><A><T><G><F><P><A><V><L><V><C><T><S><G><T><A><V><A><N><Y><L><P><A><V><V><E><A><S><N><D><R><I><P><M><L><I><L><S><A><D><R...
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).<BOP>
A4SD60
O75385
ULK1_HUMAN
Unc-51-like kinase 1
Homo
<M><E><P><G><R><G><G><T><E><T><V><G><K><F><E><F><S><R><K><D><L><I><G><H><G><A><F><A><V><V><F><K><G><R><H><R><E><K><H><D><L><E><V><A><V><K><C><I><N><K><K><N><L><A><K><S><Q><T><L><L><G><K><E><I><K><I><L><K><E><L><K><H><E><N><I><V><A><L><Y><D><F><Q><E><M><A><N><S><V><Y><L><V><M><E><Y><C><N><G><G><D><L><A><D><Y><L><H><A><M...
Serine/threonine-protein kinase involved in autophagy in response to starvation . Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes . Part of regulatory feedback loops in autophagy: acts both as a downstream effector and negative regulat...
O75385
Q9F2F9
ELMGT_STROV
Elloramycin glycosyltransferase ElmGT
Streptomyces
<M><R><V><L><A><V><A><T><P><A><L><G><H><L><F><P><A><V><P><L><L><W><A><L><R><A><R><G><D><E><V><L><V><V><T><G><G><D><A><L><R><V><A><E><A><G><L><P><V><V><D><A><L><P><G><E><T><L><T><T><L><F><G><A><Y><Q><E><T><D><P><A><F><F><V><A><L><R><R><S><P><M><T><T><L><R><D><L><A><P><V><L><A><Y><L><A><G><R><L><L><E><P><A><R><R><A><A><E...
Glycosyltransferase that transfers an L-rhamnose moiety from dTDP-L-rhamnose to the elloramycin aglycone 8-demethyl-tetracenomycin C (8DMTC) in elloramycin biosynthesis, an antitumor polyketide. Possesses donor substrate flexibility: able to transfer at least 11 different sugars to 8DMTC, such as NDP-D-glucose, as well...
Q9F2F9
G1UH28
CHIT_PUNGR
Pomegranate seed chitinase
Punica
<M><A><K><T><L><P><F><S><R><A><L><L><L><S><L><S><I><L><L><V><A><R><A><I><S><A><G><D><I><A><I><Y><W><G><Q><N><G><G><E><G><T><L><A><S><T><C><D><T><G><R><Y><A><Y><V><I><V><S><F><V><T><T><F><G><N><F><R><A><P><V><V><N><L><A><G><H><C><D><P><A><A><G><T><C><T><G><L><S><D><E><I><R><S><C><Q><G><K><D><I><K><V><L><M><S><I><G><G><G...
Hydrolyzes chitin. Probable calcium storage protein of the seeds. Binds calcium ions with high capacity and low affinity. Involved in seed germination.<BOP>
G1UH28
G5EGK8
PP2A_CAEEL
Serine/threonine-protein phosphatase 2A catalytic subunit
Caenorhabditis
<M><A><A><A><P><P><S><A><D><P><L><D><K><A><L><I><V><D><V><D><Q><W><I><E><Q><L><Y><E><C><K><P><L><S><E><N><Q><V><K><T><L><C><E><K><A><K><E><I><L><E><K><E><P><N><V><Q><E><V><R><C><P><V><T><V><C><G><D><V><H><G><Q><F><H><D><L><M><E><L><F><K><M><G><G><K><S><P><D><T><N><Y><L><F><M><G><D><Y><V><D><R><G><Y><Y><S><V><E><T><V><S...
Protein phosphatase which plays an essential role in early embryonic cell division . Probably together with constant regulatory subunit paa-1 and regulatory subunit sur-6, positively regulates centriole duplication by preventing the degradation of sas-5 and kinase zyg-1 . In addition, plays a role in the recruitment of...
G5EGK8
O04609
WRK22_ARATH
WRKY DNA-binding protein 22
Arabidopsis
<M><A><D><D><W><D><L><H><A><V><V><R><G><C><S><A><V><S><S><S><A><T><T><T><V><Y><S><P><G><V><S><S><H><T><N><P><I><F><T><V><G><R><Q><S><N><A><V><S><F><G><E><I><R><D><L><Y><T><P><F><T><Q><E><S><V><V><S><S><F><S><C><I><N><Y><P><E><E><P><R><K><P><Q><N><Q><K><R><P><L><S><L><S><A><S><S><G><S><V><T><S><K><P><S><G><S><N><T><S><R...
Transcription factor involved in the expression of defense genes in innate immune response of plants. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element. Activates WRKY 29, SIRK and its own promoters.<BOP>
O04609
A9II17
NUOH_BORPD
NDH-1 subunit H
Bordetella
<M><E><W><L><D><I><L><E><S><H><G><Q><A><L><L><G><P><T><A><W><L><V><L><W><T><I><V><K><I><V><V><I><A><V><P><I><I><L><C><V><A><Y><L><T><Y><W><E><R><K><M><I><G><W><M><H><V><R><L><G><P><T><R><V><G><F><R><G><L><L><Q><P><F><A><D><V><F><K><L><L><T><K><E><V><V><V><P><T><Q><A><N><K><I><L><F><V><V><A><P><V><V><T><L><M><P><A><L><A...
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are t...
A9II17
P29068
CBPT_THEVU
Carboxypeptidase T
Thermoactinomyces
<M><R><K><K><W><L><S><L><S><L><V><L><V><L><I><V><A><C><V><P><A><L><G><F><S><Q><N><I><E><N><P><S><I><F><D><L><G><I><K><L><Y><K><I><D><G><V><S><T><K><E><Q><R><S><A><I><A><S><T><G><A><A><I><E><E><V><G><K><D><Y><V><K><V><L><A><T><P><S><E><A><K><Q><I><K><Q><K><G><F><T><A><T><V><D><T><S><L><T><T><Q><D><F><P><S><Y><D><S><G><Y...
Able to split off hydrophobic and basic amino acids with comparable efficiency.<BOP>
P29068
Q5E7K1
RF3_ALIF1
Peptide chain release factor 3
Aliivibrio
<M><S><F><L><Q><E><V><G><K><R><R><T><F><A><I><I><S><H><P><D><A><G><K><T><T><I><T><E><K><V><L><L><F><G><N><A><I><Q><K><A><G><T><V><K><G><R><G><S><N><Q><H><A><K><S><D><W><M><E><M><E><K><E><R><G><I><S><V><T><T><S><V><M><Q><F><P><F><N><D><C><L><V><N><L><L><D><T><P><G><H><E><D><F><S><E><D><T><Y><R><T><L><T><A><V><D><S><C><L...
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.<BOP>
Q5E7K1
B7LTW5
PDUL_ESCF3
Propanediol utilization protein PduL
Escherichia
<M><D><K><Q><L><L><E><T><A><V><G><K><V><L><E><E><M><R><E><R><P><I><P><L><G><I><S><N><R><H><I><H><L><S><A><Q><D><F><A><H><L><F><P><G><Q><S><I><S><V><K><K><A><L><M><Q><P><D><Q><Y><A><A><E><Q><T><L><T><L><V><G><P><K><G><K><L><E><K><V><R><L><L><G><P><L><R><S><A><S><Q><V><E><V><S><R><T><D><A><R><T><L><G><I><T><A><P><L><R><M...
Involved in 1,2-propanediol (1,2-PD) utilization within the bacterial microcompartment (BMC) dedicated to 1,2-PD degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.<BOP>
B7LTW5
P37293
NAT2_YEAST
Amino-terminal, alpha-amino, acetyltransferase 2
Saccharomyces
<M><M><V><P><R><I><S><A><S><P><V><F><K><R><I><F><L><R><W><G><F><V><T><L><P><I><Q><K><T><V><S><H><T><L><R><R><D><F><S><A><P><C><R><S><M><V><K><C><L><L><L><R><P><G><I><S><V><H><S><A><Q><D><R><K><F><Y><S><T><E><E><K><S><S><Q><F><D><E><N><K><S><K><S><N><N><G><K><K><N><E><P><H><G><I><K><G><L><M><A><K><Y><G><Y><S><A><L><I><V...
Maybe involved in N-terminal acetylation of proteins. N-acetylation plays a role in normal eukaryotic translation and processing, protect against proteolytic degradation and protein turnover.<BOP>
P37293
O83361
MURC_TREPA
UDP-N-acetylmuramoyl-L-alanine synthetase
Treponema
<M><K><R><G><T><L><P><K><D><V><S><G><I><K><I><H><M><I><G><I><K><G><T><G><M><S><A><L><A><E><L><L><C><A><R><G><A><R><V><S><G><S><D><V><A><D><V><F><Y><T><D><R><I><L><A><R><L><G><V><P><V><R><T><P><F><S><C><Q><N><L><A><D><A><P><D><V><V><I><H><S><A><A><Y><V><P><E><E><N><D><E><L><A><E><A><Y><R><R><G><I><P><T><L><T><Y><P><E><A...
Cell wall formation.<BOP>
O83361
A4J778
METRE_DESRM
Metal reductase
Desulforamulus
<M><S><I><L><F><S><P><A><Q><I><G><T><L><Q><L><R><N><R><I><I><M><T><P><M><H><L><G><Y><T><P><N><G><E><V><T><D><Q><L><I><E><F><Y><R><V><R><A><R><G><G><A><G><L><I><V><V><G><G><C><G><I><D><R><I><G><N><A><Y><G><M><T><Q><L><D><D><D><R><F><I><P><G><L><R><R><L><A><D><A><V><Q><A><E><G><A><K><I><V><A><Q><L><Y><Q><A><G><R><Y><A><H...
Metal reductase able to reduce Fe(III)-chelates to Fe(II)-chelates, as well as soluble Cr(VI) and U(VI), using NADH as electron donor. Cannot use NADPH as an electron donor. Is unable to reduce riboflavin and FMN with NADH as electron donor. May have an in vivo role in metal reduction in D.reducens, which is an organis...
A4J778
B5Y6R9
GCH4_COPPD
GTP cyclohydrolase FolE2
Coprothermobacter
<M><R><D><V><Q><S><E><R><D><P><R><N><V><P><L><D><Y><V><G><I><E><N><V><R><L><P><I><T><V><R><T><K><E><G><G><K><Q><P><T><V><G><T><F><S><I><G><V><D><F><P><H><S><F><R><G><T><H><M><S><R><F><M><E><V><L><Y><Q><H><L><E><E><I><S><Q><T><R><L><R><V><T><L><E><D><I><K><E><R><L><K><A><T><K><A><M><I><E><V><A><F><P><F><A><I><K><K><S><T...
Converts GTP to 7,8-dihydroneopterin triphosphate.<BOP>
B5Y6R9
Q6P7Q1
BABA2_RAT
Brain and reproductive organ-expressed protein
Rattus
<M><S><P><E><I><A><L><N><R><I><S><P><M><L><S><P><F><I><S><S><V><V><R><N><G><K><V><G><L><D><A><T><N><C><L><R><I><T><D><L><K><S><G><C><T><S><L><T><P><G><P><N><C><D><R><F><K><L><H><I><P><Y><A><G><E><T><L><K><W><D><I><I><F><N><A><Q><Y><P><E><L><P><P><D><F><I><F><G><E><D><A><E><F><L><P><D><P><S><A><L><H><N><L><A><S><W><N><P...
Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specific...
Q6P7Q1
Q8P2R7
TADA_STRP8
tRNA-specific adenosine deaminase
Streptococcus
<M><P><Y><S><L><E><E><Q><T><Y><F><M><Q><E><A><L><K><E><A><E><K><S><L><Q><K><A><E><I><P><I><G><C><V><I><V><K><D><G><E><I><I><G><R><G><H><N><A><R><E><E><S><N><Q><A><I><M><H><A><E><M><M><A><I><N><E><A><N><A><H><E><G><N><W><R><L><L><D><T><T><L><F><V><T><I><E><P><C><V><M><C><S><G><A><I><G><L><A><R><I><P><H><V><I><Y><G><A><S...
Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).<BOP>
Q8P2R7
A3CVJ2
PCNA_METMJ
Proliferating cell nuclear antigen homolog
Methanoculleus
<M><L><K><A><T><I><D><A><E><I><F><R><E><S><I><D><A><I><A><A><L><V><T><E><C><R><L><H><T><A><E><D><Q><I><R><T><R><S><V><D><T><A><N><V><A><M><V><S><L><E><L><Q><S><T><A><F><N><S><F><S><A><T><A><G><E><L><G><L><D><I><A><K><M><K><N><I><I><G><M><M><G><K><G><D><A><L><T><L><T><L><L><D><E><E><R><K><L><E><L><S><F><G><G><Y><R><Y><S...
Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.<BOP>
A3CVJ2
Q8VF12
OL495_MOUSE
Olfactory receptor 204-37
Mus
<M><A><F><L><E><D><G><N><H><T><I><V><T><E><F><I><L><L><G><L><T><D><D><P><V><L><R><D><I><L><F><T><I><I><L><C><I><Y><L><V><T><V><S><G><N><L><S><T><I><L><L><I><R><V><S><S><Q><L><H><H><P><M><Y><F><F><L><S><H><L><A><S><V><D><I><G><I><S><S><S><V><T><P><N><M><L><A><N><F><L><V><K><P><N><T><I><S><Y><I><G><C><S><I><Q><F><T><S><A...
Potential odorant receptor.<BOP>
Q8VF12
C1CTY2
MUTS_STRZT
DNA mismatch repair protein MutS
Streptococcus
<M><A><I><E><K><L><S><P><G><M><Q><Q><Y><V><D><I><K><K><Q><Y><P><D><A><F><L><L><F><R><M><G><D><F><Y><E><L><F><Y><E><D><A><V><N><A><A><Q><I><L><E><I><S><L><T><S><R><N><K><N><A><D><N><P><I><P><M><A><G><V><P><Y><H><S><A><Q><Q><Y><I><D><V><L><I><E><Q><G><Y><K><V><A><I><A><E><Q><M><E><D><P><K><Q><A><V><G><V><V><K><R><E><V><V...
This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.<BOP>
C1CTY2
Q4UJN0
LPXB_RICFE
Lipid-A-disaccharide synthase
spotted fever group
<M><T><K><I><Y><F><I><A><G><E><T><S><G><D><F><I><G><G><R><I><I><Q><H><L><K><D><N><I><E><I><K><C><M><G><V><G><G><K><Y><M><E><E><A><G><S><F><K><S><L><F><S><I><T><S><I><N><L><M><G><F><V><E><I><L><P><H><I><F><K><L><K><K><L><I><D><K><T><V><E><D><I><T><N><S><R><A><D><L><L><I><T><I><D><S><P><G><F><T><Y><R><V><A><K><R><V><R><K...
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.<BOP>
Q4UJN0
Q9Z8T3
RIMO_CHLPN
Ribosome maturation factor RimO
Chlamydia
<M><T><T><K><S><L><G><S><F><N><S><V><I><S><K><N><K><I><H><F><I><S><L><G><C><S><R><N><L><V><D><S><E><V><M><L><G><I><L><L><K><A><G><Y><E><S><T><N><E><I><E><D><A><D><Y><L><I><L><N><T><C><A><F><L><K><S><A><R><D><E><A><K><D><Y><L><D><H><L><I><D><V><K><K><E><N><A><K><I><I><V><T><G><C><M><T><S><N><H><K><D><E><L><K><P><W><M><S...
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.<BOP>
Q9Z8T3
Q8ZMF5
CYSN_SALTY
Sulfate adenylate transferase
Salmonella
<M><N><T><I><L><A><Q><Q><I><A><N><E><G><G><V><E><A><W><M><I><A><Q><Q><H><K><S><L><L><R><F><L><T><C><G><S><V><D><D><G><K><S><T><L><I><G><R><L><L><H><D><T><L><Q><I><Y><E><D><Q><L><S><S><L><H><N><D><S><K><R><H><G><T><Q><G><E><K><L><D><L><A><L><L><V><D><G><L><Q><A><E><R><E><Q><G><I><T><I><D><V><A><Y><R><Y><F><S><T><E><R><R...
With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysi...
Q8ZMF5
Q9LVB0
AHL6_ARATH
AT-hook motif nuclear-localized protein 6
Arabidopsis
<M><E><E><K><G><E><I><S><P><S><G><V><V><T><V><K><G><D><E><A><L><V><P><R><T><E><F><Q><Q><N><P><S><F><L><Q><F><V><S><P><T><T><V><V><T><P><L><P><P><P><P><A><P><S><S><A><P><V><P><T><T><V><T><P><G><S><A><T><A><S><T><G><S><D><P><T><K><K><K><R><G><R><P><R><K><Y><A><P><D><G><S><L><N><P><R><F><L><R><P><T><L><S><P><T><P><I><S><S...
Transcription factor that specifically binds AT-rich DNA sequences related to the nuclear matrix attachment regions (MARs).<BOP>
Q9LVB0
A4XVG4
LPXH_PSEMY
UDP-2,3-diacylglucosamine diphosphatase
Pseudomonas
<M><I><L><L><I><S><D><L><H><L><E><E><K><R><P><D><I><T><R><A><F><L><H><F><L><A><T><R><A><R><Q><A><E><A><L><Y><I><L><G><D><F><F><E><V><W><I><G><D><D><G><M><T><P><F><Q><H><E><I><A><G><A><L><R><E><L><S><D><S><G><T><R><I><Y><L><M><H><G><N><R><D><F><L><I><G><K><R><F><C><R><E><A><G><C><T><L><L><G><D><P><H><R><V><Q><M><N><G><E...
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.<B...
A4XVG4
Q8FBP9
WECF_ECOL6
TDP-Fuc4NAc:lipid II Fuc4NAc transferase
Escherichia
<M><T><V><L><I><H><V><L><G><S><D><I><P><H><H><N><R><T><V><L><R><F><F><N><D><A><L><A><A><T><S><E><H><A><R><E><F><M><V><A><G><K><D><D><G><L><S><D><S><C><L><A><L><S><V><Q><F><F><P><G><K><K><S><L><A><E><A><V><I><A><K><A><K><A><N><R><Q><Q><R><F><F><F><H><G><Q><F><N><P><K><L><W><L><A><L><L><S><G><G><I><K><P><S><Q><F><F><W><H...
Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis.<BOP>
Q8FBP9
Q83HY0
ATPB_TROW8
F-ATPase subunit beta
Tropheryma
<M><T><G><D><A><V><G><R><I><V><R><V><T><G><S><V><V><D><V><E><F><S><R><N><N><L><P><G><V><F><N><A><L><K><T><R><V><N><R><S><G><K><E><I><E><I><T><L><E><V><A><Q><H><L><G><D><D><L><V><R><T><V><A><M><Q><S><T><D><G><L><I><R><G><Q><E><V><L><D><T><G><G><H><I><T><V><P><V><G><D><A><T><K><G><R><V><F><N><V><V><G><E><V><L><N><S><N><G...
Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.<BOP>
Q83HY0
P18296
CUT1_SCHPO
Separase
Schizosaccharomyces
<M><S><T><R><S><I><V><T><S><K><V><S><W><T><P><E><K><F><I><S><A><L><S><Y><P><E><H><C><S><I><T><L><V><K><R><L><K><A><S><V><K><L><K><D><L><K><Q><N><I><S><R><D><A><P><S><W><T><F><E><H><L><F><V><A><F><K><C><A><V><S><N><L><A><K><Q><W><A><E><L><S><T><T><D><K><E><K><T><R><R><M><F><C><T><P><S><R><L><N><T><A><H><R><P><E><V><F><Y...
Caspase-like protease, which plays a central role in the chromosome segregation by cleaving the rad21 subunit of the cohesin complex at the onset of anaphase. During most of the cell cycle, it is inactivated by securin/cut2 protein. It is also required for pointed nuclear formation.<BOP>
P18296
Q7VQX1
HIS1_BLOFL
ATP phosphoribosyltransferase
Candidatus Blochmannia
<M><L><D><K><S><R><L><R><I><A><M><Q><K><S><G><R><L><S><K><E><S><Q><K><L><L><E><Q><C><G><I><K><I><N><L><Q><Q><Q><Q><L><L><A><F><A><E><N><M><T><I><D><I><M><R><V><R><D><D><D><I><P><G><L><I><M><D><G><V><V><D><L><G><I><I><G><E><N><V><L><E><E><A><L><L><T><R><Q><S><Q><G><D><N><P><C><Y><V><T><L><R><R><L><D><F><G><D><C><R><L><S...
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.<BOP>
Q7VQX1
P20802
TBB_ACHKL
Beta-tubulin
Achlya
<M><R><E><L><V><H><I><Q><G><G><Q><C><G><N><Q><I><G><A><K><F><W><E><V><I><S><D><E><H><G><V><D><P><T><G><S><Y><H><G><D><S><D><L><Q><L><E><R><I><N><V><Y><Y><N><E><A><T><G><T><Y><V><P><R><A><I><L><M><D><L><E><P><G><T><M><D><S><V><R><A><G><P><Y><G><Q><L><F><R><P><D><N><F><V><F><G><Q><T><G><A><G><N><N><W><A><K><G><H><Y><T><E...
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-...
P20802
P59108
CPNE2_MOUSE
Copine II
Mus
<M><A><Y><I><P><D><G><G><A><P><T><A><G><A><I><P><L><G><S><Q><C><C><V><C><K><V><E><L><S><V><S><G><Q><N><L><L><D><R><D><V><T><S><K><S><D><P><F><C><V><L><F><I><E><D><N><G><R><W><M><E><F><D><R><T><E><T><A><V><N><N><L><N><P><A><F><S><K><K><F><V><L><D><Y><H><F><E><E><V><Q><K><L><K><F><A><L><F><D><Q><D><K><S><S><A><Q><L><D><E...
Calcium-dependent phospholipid-binding protein that plays a role in calcium-mediated intracellular processes. Exhibits calcium-dependent cell membrane binding properties .<BOP>
P59108
A8LRT3
ALR_DINSH
Alanine racemase
Dinoroseobacter
<M><A><T><A><T><L><S><I><D><L><D><A><I><A><A><N><W><R><A><L><D><R><A><S><N><R><R><V><A><T><G><A><V><V><K><A><D><G><Y><G><L><D><A><G><R><V><A><R><T><L><A><Q><A><G><A><R><Q><F><F><V><A><V><A><E><E><G><V><T><L><R><K><A><L><G><P><G><P><A><I><N><V><F><S><G><H><M><E><G><D><T><Q><A><I><A><G><A><R><L><T><P><M><I><N><S><A><E><Q...
Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.<BOP>
A8LRT3
Q11KP9
KATG_CHESB
Peroxidase/catalase
unclassified Chelativorans
<M><D><A><K><T><D><D><S><A><G><K><C><P><F><T><G><G><G><R><R><G><H><R><N><R><D><W><W><P><E><Q><L><D><L><D><V><L><H><R><N><S><T><L><S><D><P><M><G><E><D><F><D><Y><A><E><E><F><K><S><L><D><L><N><A><V><I><Q><D><L><H><A><L><M><T><D><S><Q><D><W><W><P><A><D><F><G><H><Y><G><G><L><M><I><R><M><A><W><H><S><A><G><T><Y><R><I><T><D><G...
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.<BOP>
Q11KP9
P13911
RPOA_PEA
Plastid-encoded RNA polymerase subunit alpha
Pisum
<M><I><R><E><K><L><K><V><S><T><Q><T><L><Q><W><K><C><V><E><S><R><V><D><S><K><R><L><Y><Y><G><R><F><I><L><S><P><L><M><K><G><Q><A><D><T><I><G><I><T><M><R><R><I><L><L><G><E><I><E><G><T><C><I><T><R><A><K><S><E><K><I><P><H><E><Y><S><T><I><V><G><I><Q><E><S><I><H><E><I><L><M><N><L><K><E><I><V><L><R><S><N><L><Y><G><T><R><E><A><S...
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.<BOP>
P13911
A7H644
RL5_CAMJD
50S ribosomal protein L5
Campylobacter
<M><M><R><L><K><E><K><Y><N><Q><S><I><K><P><A><L><V><K><E><F><D><I><K><N><P><M><L><I><P><V><I><E><K><V><V><I><S><V><G><A><G><E><L><A><K><D><Q><K><V><L><Q><N><V><A><D><T><I><S><L><I><A><G><Q><K><A><V><I><T><K><A><K><K><S><V><A><G><F><K><V><R><E><G><F><P><I><G><V><M><V><T><L><R><K><E><N><M><Y><A><F><L><D><K><L><I><S><I><A...
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement...
A7H644
E7FHN9
HYD2B_PYRFU
Sulfur reductase subunit ShyB
Pyrococcus
<M><R><Y><V><K><L><H><S><E><Y><F><P><E><F><F><N><R><L><K><E><V><G><R><V><Y><G><P><V><R><H><N><S><T><Y><R><F><E><E><V><N><S><I><D><E><L><S><L><D><Y><T><R><T><I><L><P><P><K><K><F><F><I><R><P><R><D><A><M><F><K><I><Q><K><N><E><V><T><E><V><D><G><D><G><K><F><V><L><F><G><V><H><S><C><D><I><H><G><I><K><I><L><D><K><V><Y><L><S><N...
Part of a bifunctional enzyme complex that functions as a hydrogen-evolving hydrogenase with sulfur-reducing activity. May play a role in hydrogen cycling during fermentative growth. Activity exhibited with NAD in addition to NADPH. The beta and gamma subunits form the sulfur-reducing component that catalyzes the cytop...
E7FHN9
B2GC51
RNH2_LIMF3
Ribonuclease HII
Limosilactobacillus
<M><S><K><Q><S><V><A><Q><V><R><A><L><L><S><S><I><T><D><P><Q><D><P><R><L><A><E><F><K><D><D><P><R><K><G><V><Q><A><A><L><N><Q><F><A><K><R><L><E><K><R><A><E><A><R><A><A><F><L><N><R><F><R><Y><E><N><Q><L><W><Q><A><G><H><Q><Y><V><A><G><I><D><E><V><G><R><G><P><L><A><G><P><V><V><T><C><A><V><V><L><D><S><Q><F><D><L><V><G><V><T><D...
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.<BOP>
B2GC51
Q481S6
GLYA2_COLP3
Serine hydroxymethyltransferase 2
Colwellia
<M><F><Y><K><N><D><Q><I><A><G><F><D><D><S><I><W><Q><A><M><E><Q><E><D><K><R><Q><Q><D><H><V><E><L><I><A><S><E><N><Y><T><S><A><R><V><M><Q><A><Q><G><S><Q><L><T><N><K><Y><A><E><G><Y><P><G><K><R><Y><Y><G><G><C><E><H><V><D><V><I><E><Q><L><A><I><D><R><A><K><E><L><F><G><A><D><Y><A><N><V><Q><P><H><S><G><S><Q><A><N><A><A><V><F><M...
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent a...
Q481S6
Q09FZ1
NU1C_PLAOC
NADH-plastoquinone oxidoreductase subunit 1
Platanus
<M><I><I><D><T><T><E><V><Q><A><I><N><S><F><S><R><S><E><S><L><K><E><A><Y><G><L><I><W><L><L><V><P><I><F><T><P><V><S><G><I><T><I><G><V><L><V><I><V><W><L><E><R><E><I><S><A><G><I><Q><Q><R><I><G><P><E><Y><A><G><P><L><G><I><L><Q><A><L><A><D><G><T><K><L><L><F><K><E><D><L><L><P><S><R><G><D><T><R><L><F><S><I><G><P><S><I><A><I><I...
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translo...
Q09FZ1
Q04911
CYB_MONDO
Ubiquinol-cytochrome-c reductase complex cytochrome b subunit
Monodelphis
<M><T><N><L><R><K><N><Y><P><L><M><K><I><I><N><H><S><F><I><D><L><P><A><P><S><N><I><S><A><W><W><N><F><G><S><L><L><G><M><C><L><I><I><Q><I><L><T><G><L><F><L><A><M><H><Y><T><S><D><T><L><T><A><F><S><S><V><A><H><I><C><R><D><V><N><Y><G><W><L><I><R><N><L><H><A><N><G><A><S><M><F><F><M><C><L><F><L><H><V><G><R><G><I><Y><Y><G><S><Y...
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is...
Q04911
Q82TP1
UBID_NITEU
Polyprenyl p-hydroxybenzoate decarboxylase
Nitrosomonas
<M><K><Y><K><D><L><R><D><F><L><V><Q><L><E><Q><R><G><D><L><K><R><V><D><I><E><V><D><P><H><L><E><M><T><E><I><C><D><R><L><L><K><Q><A><G><P><A><V><L><F><E><R><P><A><G><H><T><I><P><V><L><G><N><L><F><G><T><P><E><R><V><A><L><G><M><G><Q><T><S><V><S><A><L><R><E><V><G><K><L><L><A><Y><L><K><E><P><D><P><P><K><G><L><R><D><A><W><E><K...
Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.<BOP>
Q82TP1
B9KH09
ATPA_ANAMF
F-ATPase subunit alpha
Anaplasma
<M><S><I><V><S><S><G><D><I><L><K><I><L><K><E><R><I><E><G><F><D><S><P><V><K><T><S><S><V><G><D><V><V><A><I><K><D><G><I><A><L><V><Y><G><L><S><G><V><K><F><G><E><T><V><A><F><S><S><G><V><R><G><V><V><A><G><L><E><R><D><T><C><S><V><V><V><F><G><E><D><R><E><I><R><E><G><D><S><V><Q><C><T><G><E><L><M><T><V><P><A><G><L><S><V><L><G><R...
Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.<BOP>
B9KH09
Q60773
CDN2D_MOUSE
p19-INK4d
Mus
<M><L><L><E><E><V><C><V><G><D><R><L><S><G><A><A><A><R><G><D><V><Q><E><V><R><R><L><L><H><R><E><L><V><H><P><D><A><L><N><R><F><G><K><T><A><L><Q><V><M><M><F><G><S><P><A><V><A><L><E><L><L><K><Q><G><A><S><P><N><V><Q><D><A><S><G><T><S><P><V><H><D><A><A><R><T><G><F><L><D><T><L><K><V><L><V><E><H><G><A><D><V><N><A><L><D><S><T><G...
Interacts strongly with CDK4 and CDK6 and inhibits them.<BOP>
Q60773
P24718
RECF_ACTPL
DNA replication and repair protein RecF
Actinobacillus
<M><P><L><S><R><L><I><I><N><N><F><R><N><L><Q><S><L><D><L><E><L><S><P><N><F><N><F><I><V><G><H><N><G><S><G><K><T><S><L><L><E><A><I><F><Y><L><G><H><G><R><S><F><K><S><H><I><S><N><R><I><I><H><Y><Q><A><E><D><F><V><L><H><A><R><I><D><E><G><Q><H><Q><W><S><V><G><I><Q><K><K><R><S><G><D><T><L><L><K><I><N><G><E><D><G><N><K><I><S><D...
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.<BOP>
P24718
Q3KP22
MAJIN_HUMAN
Membrane-anchored junction protein
Homo
<M><S><L><K><P><F><T><Y><P><F><P><E><T><R><F><L><H><A><G><P><N><V><Y><K><F><K><I><R><Y><G><K><S><I><R><G><E><E><I><E><N><K><E><V><I><T><Q><E><L><E><V><P><V><E><K><K><A><V><G><A><V><M><R><K><R><K><H><M><D><E><P><S><S><P><S><R><P><G><L><D><R><A><K><I><G><T><S><S><Q><G><P><S><K><K><K><P><P><V><E><T><R><R><N><R><E><R><K><T...
Meiosis-specific telomere-associated protein involved in meiotic telomere attachment to the nucleus inner membrane, a crucial step for homologous pairing and synapsis. Component of the MAJIN-TERB1-TERB2 complex, which promotes telomere cap exchange by mediating attachment of telomeric DNA to the inner nuclear membrane ...
Q3KP22
D0LHE3
BMCT1_HALO1
Bacterial microcompartment protein trimer-1
Haliangium
<M><D><H><A><P><E><R><F><D><A><T><P><P><A><G><E><P><D><R><P><A><L><G><V><L><E><L><T><S><I><A><R><G><I><T><V><A><D><A><A><L><K><R><A><P><S><L><L><L><M><S><R><P><V><S><S><G><K><H><L><L><M><M><R><G><Q><V><A><E><V><E><E><S><M><I><A><A><R><E><I><A><G><A><G><S><G><A><L><L><D><E><L><E><L><P><Y><A><H><E><Q><L><W><R><F><L><D><A...
A minor component of the bacterial microcompartment (BMC) shell. Expression of 5 proteins in E.coli (BMC-H (Hoch_5815), BMC-P (Hoch_5814), and 3 BMC-T (Hoch_5812, Hoch_5816, Hoch_3341)) forms 40 nm artificial BMCs with a molecular mass of 6.5 MDa. This protein does not form stacked pseudohexamers in the BMC. There are ...
D0LHE3
Q3BVY7
RL19_XANC5
50S ribosomal protein L19
Xanthomonas
<M><S><K><L><N><K><T><I><L><A><D><F><E><A><A><Q><I><Q><R><K><L><P><E><F><N><Q><G><D><T><V><V><V><N><V><K><V><K><E><G><N><R><E><R><V><Q><A><Y><E><G><V><V><I><G><T><K><N><A><G><L><N><S><S><F><T><V><R><K><I><S><H><G><F><G><V><E><R><V><F><Q><T><H><S><A><I><I><D><S><V><E><V><K><R><R><G><K><V><R><A><G><K><L><Y><Y><L><R><G><L...
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.<BOP>
Q3BVY7
P16451
ODPX_YEAST
Pyruvate dehydrogenase complex component E3BP
Saccharomyces
<M><L><S><A><I><S><K><V><S><T><L><K><S><C><T><R><Y><L><T><K><C><N><Y><H><A><S><A><K><L><L><A><V><K><T><F><S><M><P><A><M><S><P><T><M><E><K><G><G><I><V><S><W><K><Y><K><V><G><E><P><F><S><A><G><D><V><I><L><E><V><E><T><D><K><S><Q><I><D><V><E><A><L><D><D><G><K><L><A><K><I><L><K><D><E><G><S><K><D><V><D><V><G><E><P><I><A><Y><I...
Required for anchoring dihydrolipoamide dehydrogenase (E3) to the dihydrolipoamide transacetylase (E2) core of the pyruvate dehydrogenase complexes of eukaryotes. This specific binding is essential for a functional PDH complex.<BOP>
P16451
B1LEG3
OPGB_ECOSM
Phosphatidylglycerol--membrane-oligosaccharide glycerophosphotransferase
Escherichia
<M><S><E><L><L><S><F><A><L><F><L><A><S><V><L><I><Y><A><W><K><A><G><R><N><T><W><W><F><A><A><T><L><T><V><L><G><L><F><V><V><L><N><I><T><L><F><A><S><D><Y><F><T><G><D><G><I><N><D><A><V><L><Y><T><L><T><N><S><L><T><G><A><G><V><S><K><Y><I><L><P><G><I><G><I><V><L><G><L><T><A><V><F><G><A><L><G><W><I><L><R><R><R><R><H><H><P><H><H...
Transfers a phosphoglycerol residue from phosphatidylglycerol to the membrane-bound nascent glucan backbones.<BOP>
B1LEG3
Q9I1W9
RGVIR_PSEAE
Putative virulence-regulating protein PA2146
Pseudomonas
<M><A><Q><H><Q><G><G><K><G><N><F><A><E><D><P><K><R><A><S><E><A><G><K><K><G><G><Q><A><S><G><G><N><F><K><N><D><P><Q><R><A><S><E><A><G><K><K><G><G><Q><R><S><H><G><G><N>
May be involved in the regulation of the production of pyocyanine, one of the major virulence factors secreted by P.aeruginosa, and other virulence factors.<BOP>
Q9I1W9
Q8XEC1
MHPD_ECO57
2-hydroxypentadienoic acid hydratase
Escherichia
<M><T><K><H><T><L><E><Q><L><A><A><D><L><R><R><A><A><E><Q><G><E><A><I><A><P><L><R><D><L><I><G><I><D><N><A><E><A><A><Y><A><I><Q><H><I><N><V><Q><Y><D><V><A><Q><G><R><R><V><V><G><R><K><V><G><L><T><H><P><K><V><Q><Q><Q><L><G><V><D><Q><P><D><F><G><T><L><F><A><D><M><C><Y><G><D><N><E><I><I><P><F><S><R><V><L><Q><P><R><I><E><A><E...
Catalyzes the conversion of 2-hydroxypentadienoic acid (enolic form of 2-oxopent-4-enoate) to 4-hydroxy-2-ketopentanoic acid.<BOP>
Q8XEC1
C4ZZN7
MUTS_ECOBW
DNA mismatch repair protein MutS
Escherichia
<M><S><A><I><E><N><F><D><A><H><T><P><M><M><Q><Q><Y><L><R><L><K><A><Q><H><P><E><I><L><L><F><Y><R><M><G><D><F><Y><E><L><F><Y><D><D><A><K><R><A><S><Q><L><L><D><I><S><L><T><K><R><G><A><S><A><G><E><P><I><P><M><A><G><I><P><Y><H><A><V><E><N><Y><L><A><K><L><V><N><Q><G><E><S><V><A><I><C><E><Q><I><G><D><P><A><T><S><K><G><P><V><E...
This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.<BOP>
C4ZZN7
Q8DSG6
GATB_STRMU
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B
Streptococcus
<M><N><F><E><T><I><I><G><L><E><V><H><V><E><L><K><T><N><S><K><I><F><S><P><A><P><A><H><F><G><E><D><P><N><A><N><T><N><I><V><D><W><S><F><P><G><V><L><P><V><M><N><K><G><V><I><D><Y><G><I><K><A><A><L><A><L><N><M><D><I><H><Q><R><M><H><F><D><R><K><N><Y><F><Y><P><D><N><P><K><A><Y><Q><I><S><Q><F><D><E><P><I><G><Y><N><G><W><I><E><I...
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated ...
Q8DSG6
B0SAC5
PANB_LEPBA
Ketopantoate hydroxymethyltransferase
Leptospira
<M><K><N><I><I><L><Q><Y><K><K><K><Y><D><A><G><E><P><I><S><V><V><T><C><Y><D><Y><T><F><A><T><L><F><N><R><T><D><V><D><C><L><L><V><G><D><S><L><G><M><V><I><Q><G><N><Q><S><T><L><P><V><T><L><D><E><I><I><Y><H><T><K><A><V><C><K><G><A><P><D><K><T><I><I><A><D><L><P><F><L><S><Y><Q><T><S><I><E><E><G><I><R><S><A><G><R><V><L><K><E><T...
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.<BOP>
B0SAC5
B6JGU6
TIG_AFIC5
PPIase
Afipia
<M><Q><V><N><E><T><L><S><E><G><L><K><H><E><F><Q><I><S><I><P><A><A><E><I><D><A><K><V><N><E><R><L><A><G><M><K><D><K><V><R><L><N><G><F><R><P><G><K><V><P><V><A><H><L><K><K><V><Y><G><K><S><V><A><A><E><T><L><E><E><T><I><R><E><T><N><Q><K><I><F><T><D><R><G><F><R><L><A><N><E><A><K><V><T><M><P><T><D><Q><A><E><I><E><G><I><L><D><G...
Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.<BOP>
B6JGU6
Q2NHB4
TRUA_METST
tRNA-uridine isomerase I
Methanosphaera
<M><R><R><V><A><L><K><I><A><Y><I><G><S><N><F><H><G><Y><Q><R><Q><P><N><Y><R><T><V><E><G><E><L><L><R><V><F><K><E><T><N><I><I><E><D><T><W><T><A><H><Y><S><V><A><G><R><T><D><K><G><V><H><S><T><G><N><V><I><S><F><I><T><D><E><D><I><H><I><N><Q><L><N><G><L><L><P><D><D><I><K><I><I><G><E><A><R><V><P><Y><G><F><K><V><R><F><P><L><T><R...
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.<BOP>
Q2NHB4
Q8KBK4
RL13_CHLTE
50S ribosomal protein L13
Chlorobaculum
<M><S><K><T><L><S><F><K><T><Y><S><A><K><P><G><E><V><K><R><T><W><H><I><I><D><A><E><N><Q><V><L><G><R><M><A><A><Q><I><A><N><V><L><R><G><K><H><K><P><Q><F><T><P><H><I><D><T><G><D><F><V><V><V><T><N><A><A><K><V><A><L><S><G><K><K><R><D><D><K><T><Y><F><S><H><S><H><Y><P><G><G><V><R><I><D><S><V><K><D><L><L><Q><K><K><P><E><K><V><I...
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.<BOP>
Q8KBK4
A4QLM9
RR8_LOBMA
30S ribosomal protein S8, chloroplastic
Lobularia
<M><G><K><D><T><I><A><D><I><I><T><S><I><R><N><A><D><M><N><R><K><G><T><V><R><I><G><S><T><N><I><T><E><S><I><V><K><I><L><L><R><E><G><F><I><E><N><V><R><K><H><R><E><N><N><Q><Y><F><L><I><L><T><L><R><H><R><R><N><K><K><E><S><H><K><T><I><L><N><L><K><R><I><S><R><P><G><L><R><I><Y><S><N><S><Q><R><I><P><R><I><L><G><G><I><G><I><V><I...
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.<BOP>
A4QLM9
B1KRQ3
RF3_SHEWM
Peptide chain release factor 3
Shewanella
<M><S><G><N><K><V><E><V><D><K><R><R><T><F><A><I><I><S><H><P><D><A><G><K><T><T><I><T><E><K><V><L><L><F><G><N><A><L><Q><K><A><G><T><V><K><G><K><K><S><G><Q><H><A><K><S><D><W><M><E><M><E><K><D><R><G><I><S><I><T><T><S><V><M><Q><F><P><Y><N><D><A><L><V><N><L><L><D><T><P><G><H><E><D><F><S><E><D><T><Y><R><T><L><T><A><V><D><S><C...
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.<BOP>
B1KRQ3
Q6L6X6
IL6_TAKRU
Interleukin-6
Takifugu
<M><A><S><I><S><Y><L><L><A><P><L><V><L><A><A><V><L><Q><P><T><A><G><A><P><L><D><A><P><T><E><S><P><A><G><E><T><S><G><E><E><A><E><T><G><S><P><D><D><A><L><A><V><A><L><E><S><V><L><G><A><T><K><L><H><K><N><E><F><L><V><E><F><Q><G><E><V><K><Y><D><F><L><D><R><Y><K><I><P><S><L><P><A><K><C><P><Y><S><N><F><G><K><D><A><C><L><R><R><L...
Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway. The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling'...
Q6L6X6
Q31XA7
TRUD_SHIBS
tRNA-uridine isomerase D
Shigella
<M><I><E><F><D><N><L><T><Y><L><H><G><K><P><Q><G><T><G><L><L><K><A><N><P><E><D><F><V><V><V><E><D><L><G><F><E><P><D><G><E><G><E><H><I><L><V><R><I><L><K><N><G><C><N><T><R><F><V><A><D><A><L><A><K><F><L><K><I><H><A><R><E><V><S><F><A><G><Q><K><D><K><H><A><V><T><E><Q><W><L><C><A><R><V><P><G><K><E><M><P><D><L><S><A><F><Q><L><E...
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.<BOP>
Q31XA7
Q92QI0
RL1_RHIME
50S ribosomal protein L1
Sinorhizobium
<M><A><K><I><A><K><R><V><Q><K><S><R><E><G><V><D><P><T><K><L><Y><G><L><T><E><A><V><T><L><V><K><E><R><A><T><A><K><F><D><E><T><I><E><V><A><M><N><L><G><V><D><P><R><H><A><D><Q><M><V><R><G><V><V><N><L><P><N><G><T><G><R><S><V><R><V><A><V><F><A><R><G><A><K><A><D><E><A><K><A><A><G><A><D><V><V><G><A><E><E><L><V><E><I><V><Q><G><G...
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.<BOP>
Q92QI0
Q3Z800
NUOB_DEHM1
NDH-1 subunit B
Dehalococcoides
<M><E><L><D><S><G><K><P><L><S><L><L><T><L><D><E><I><D><Q><H><E><G><G><I><I><Q><S><F><R><T><G><H><T><T><P><Y><P><D><P><A><D><W><L><N><S><E><E><P><P><P><G><V><F><V><T><S><V><E><K><V><L><N><W><S><R><H><Y><S><L><W><P><V><M><F><G><L><A><C><C><A><I><E><M><M><C><M><A><A><S><R><W><D><L><A><R><F><G><M><D><I><F><R><A><S><P><R><Q...
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are t...
Q3Z800
Q9U2M4
HOT_CAEEL
3-Hydroxypropionate-oxoacid transhydrogenase
Caenorhabditis
<M><S><A><S><L><A><R><G><I><L><S><K><M><G><G><S><C><C><P><H><H><A><P><A><T><N><P><F><K><L><A><K><L><H><G><N><N><K><S><T><D><Y><A><F><E><M><V><C><S><T><L><R><F><G><K><G><V><T><L><E><I><G><Y><D><V><R><N><L><G><A><K><K><T><L><L><I><T><D><K><N><V><Q><N><T><I><A><F><K><N><A><E><Q><A><L><K><M><V><N><I><E><Y><E><V><F><D><D><V...
Catalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of 2-ketoglutarate (2-KG) to D-2-hydroxyglutarate (D-2-HG). L-3-hydroxybutyrate (L-3-OHB) is also a substrate for HOT when using 2-KG as hydrogen acceptor, resulting in the formatio...
Q9U2M4
D7UTD1
BSC9_ALTBR
null
Alternaria sect. Brassicicola
<M><A><S><T><S><S><T><S><T><D><G><H><L><N><I><R><P><M><V><H><G><S><D><K><K><L><N><F><G><A><Y><I><T><G><L><D><L><N><N><A><S><D><A><E><V><D><Q><L><R><E><A><I><L><R><H><K><I><V><V><I><K><G><Q><Q><A><E><K><P><D><K><N><W><E><M><I><K><K><L><D><P><M><H><H><M><I><T><Q><E><E><F><G><Q><L><F><H><P><T><G><E><G><L><I><A><M><L><K><L...
Alpha-ketoglutarate dependent dioxygenase; part of the gene cluster that mediates the biosynthesis of the diterpene glucoside brassicicene C . In the first step of the brassicicene C biosynthesis, the bifunctionnal diterpene synthase bsc8 that possesses both prenyl transferase and terpene cyclase activity, converts iso...
D7UTD1
Q2U038
KYNU1_ASPOR
L-kynurenine hydrolase 1
Aspergillus subgen. Circumdati
<M><G><S><R><L><H><V><Q><E><I><K><K><G><P><P><L><P><F><K><D><D><I><R><A><F><T><R><E><Y><A><E><S><L><D><A><Q><D><P><L><R><H><F><R><D><E><F><I><I><P><S><K><K><D><L><K><R><K><T><L><N><A><N><E><N><I><E><D><S><S><D><P><R><S><I><Y><L><C><G><N><S><L><G><L><Q><P><R><N><T><R><K><Y><L><E><H><Y><L><R><T><W><A><I><K><G><V><T><G><H...
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.<BOP>
Q2U038
Q9CD75
G6PI_MYCLE
Phosphohexose isomerase
Mycobacterium
<M><T><S><M><Q><A><I><P><D><I><T><A><T><P><A><W><D><A><L><R><R><H><H><D><E><I><G><A><T><H><L><R><Q><F><F><A><D><N><P><N><R><G><R><E><L><V><I><T><V><G><D><L><Y><I><D><Y><S><K><H><R><I><T><H><D><T><V><Q><L><L><V><D><L><A><R><A><A><N><L><E><Q><R><R><D><Q><M><L><A><G><V><H><V><N><T><S><E><N><R><S><V><L><H><T><A><L><R><L><P...
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.<BOP>
Q9CD75
Q6INS5
RN168_XENLA
RING-type E3 ubiquitin transferase rnf168
Xenopus
<M><T><K><E><K><T><L><P><L><P><R><S><E><C><I><C><P><I><C><Q><E><I><L><L><E><P><V><T><L><P><C><K><H><T><L><C><N><P><C><F><Q><M><T><V><E><K><A><S><L><C><C><P><F><C><R><K><R><V><S><T><W><A><R><L><H><S><R><T><R><T><L><V><N><T><E><L><W><E><R><I><Q><K><Q><Y><P><K><E><C><Q><R><R><A><S><G><Q><E><S><D><D><L><A><D><E><L><A><S><C...
E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with ube2n/ubc13 to amplify the rnf8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and ubiquitinates histone H2A and H2AX, lea...
Q6INS5
P40402
SSUD_BACSU
FMNH2-dependent aliphatic sulfonate monooxygenase
Bacillus
<M><E><I><L><W><F><I><P><T><H><G><D><A><R><Y><L><G><S><E><S><D><G><R><T><A><D><H><L><Y><F><K><Q><V><A><Q><A><A><D><R><L><G><Y><T><G><V><L><L><P><T><G><R><S><C><E><D><P><W><L><T><A><S><A><L><A><G><E><T><K><D><L><K><F><L><V><A><V><R><P><G><L><M><Q><P><S><L><A><A><R><M><T><S><T><L><D><R><I><S><D><G><R><L><L><I><N><V><V><A...
Catalyzes the desulfonation of aliphatic sulfonates.<BOP>
P40402
O00469
PLOD2_HUMAN
Lysyl hydroxylase 2
Homo
<M><G><G><C><T><V><K><P><Q><L><L><L><L><A><L><V><L><H><P><W><N><P><C><L><G><A><D><S><E><K><P><S><S><I><P><T><D><K><L><L><V><I><T><V><A><T><K><E><S><D><G><F><H><R><F><M><Q><S><A><K><Y><F><N><Y><T><V><K><V><L><G><Q><G><E><E><W><R><G><G><D><G><I><N><S><I><G><G><G><Q><K><V><R><L><M><K><E><V><M><E><H><Y><A><D><Q><D><D><L><V...
Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links.<BOP>
O00469
Q6ING2
PUS10_XENLA
tRNA-uridine isomerase
Xenopus
<M><L><L><I><E><E><K><Y><R><S><V><A><Q><V><L><L><S><S><G><T><C><S><R><C><V><L><R><F><C><C><V><G><S><P><A><N><Y><R><L><P><C><K><E><V><T><Y><E><L><Q><K><Y><L><S><H><G><D><P><A><E><E><N><D><T><P><P><S><K><K><A><K><I><E><E><D><T><S><S><N><E><H><L><G><N><C><E><D><V><N><G><S><Q><V><V><R><I><C><P><L><C><L><G><I><L><Q><Q><F><C...
Protein with different functions depending on its subcellular location: involved in miRNA processing in the nucleus and acts as a tRNA pseudouridylate synthase in the cytoplasm. In the cytoplasm, acts as a pseudouridylate synthase by catalyzing synthesis of pseudouridine(54) and pseudouridine(55) from uracil-54 and ura...
Q6ING2
B8EA98
IHFB_SHEB2
Integration host factor subunit beta
Shewanella
<M><T><K><S><E><L><I><E><K><L><A><T><R><Q><S><Q><L><S><A><K><E><V><E><G><A><I><K><E><M><L><E><Q><M><A><T><T><L><E><S><G><D><R><I><E><I><R><G><F><G><S><F><S><L><H><Y><R><A><P><R><T><G><R><N><P><K><T><G><S><S><V><D><L><E><G><K><Y><V><P><H><F><K><P><G><K><E><L><R><E><R><V><D><A><V><N><V>
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.<BOP>
B8EA98
Q5SJE2
MTNA_THET8
S-methyl-5-thioribose-1-phosphate isomerase
Thermus
<M><D><R><V><L><P><F><R><F><A><E><E><E><G><V><F><W><L><L><D><Q><R><R><L><P><Q><E><E><V><Y><V><P><V><R><T><A><R><E><M><A><Q><A><I><R><D><M><V><V><R><G><A><P><A><I><G><V><S><A><A><F><G><M><V><L><A><H><L><A><G><E><D><L><E><E><A><D><R><R><L><R><A><S><R><P><T><A><V><N><L><F><H><A><L><D><R><M><R><P><F><W><G><D><L><A><G><S><L...
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).<BOP>
Q5SJE2
A5CQM6
METXA_CLAM3
Homoserine transacetylase
Clavibacter
<M><T><D><A><Q><I><R><S><L><I><G><R><P><P><A><S><G><A><W><R><E><G><D><P><V><A><D><R><L><F><A><S><V><G><G><V><D><L><E><A><G><G><R><I><P><S><V><R><V><A><Y><E><T><F><G><E><R><D><P><D><G><G><N><A><V><L><V><L><H><A><L><T><G><D><S><H><L><R><G><P><A><G><P><G><Q><P><T><G><G><W><W><S><G><I><V><G><P><G><L><A><I><D><T><D><R><W><F...
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.<BOP>
A5CQM6
A0QKT1
GLMM_MYCA1
Phosphoglucosamine mutase
Mycobacterium avium complex (MAC)
<M><G><R><L><F><G><T><D><G><V><R><G><V><A><N><R><E><L><T><A><E><L><A><L><A><L><G><A><A><A><A><R><Q><L><A><S><G><S><A><P><G><R><R><V><A><V><I><G><R><D><P><R><A><S><G><E><M><L><E><A><A><V><I><A><G><L><T><S><Q><G><V><D><A><L><R><V><G><V><L><P><T><P><A><V><A><Y><L><T><G><A><Y><D><A><D><F><G><V><M><I><S><A><S><H><N><P><M><P...
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.<BOP>
A0QKT1
P0DPD7
EFMT4_HUMAN
EEF1A lysine methyltransferase 4
Homo
<M><A><S><P><G><A><G><R><A><P><P><E><L><P><E><R><N><C><G><Y><R><E><V><E><Y><W><D><Q><R><Y><Q><G><A><A><D><S><A><P><Y><D><W><F><G><D><F><S><S><F><R><A><L><L><E><P><E><L><R><P><E><D><R><I><L><V><L><G><C><G><N><S><A><L><S><Y><E><L><F><L><G><G><F><P><N><V><T><S><V><D><Y><S><S><V><V><V><A><A><M><Q><A><R><H><A><H><V><P><Q><L...
Protein-lysine methyltransferase that efficiently catalyzes three successive methylations on 'Lys-36' in eukaryotic translation elongation factor 1 alpha (EEF1A1 or EEF1A2).<BOP>
P0DPD7
Q9RXK7
RS12_DEIRA
30S ribosomal protein S12
Deinococcus
<M><P><T><T><Q><Q><L><L><R><K><G><R><K><V><L><Q><K><K><S><K><V><P><A><L><K><G><S><P><F><R><R><G><V><C><T><V><V><K><T><T><T><P><K><K><P><N><S><A><L><R><K><I><A><R><V><R><L><S><S><G><F><E><V><T><A><Y><I><P><G><E><G><H><N><L><Q><E><H><S><V><V><L><I><R><G><G><R><V><K><D><L><P><G><V><R><Y><H><I><V><R><G><S><L><D><T><Q><G><V...
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The com...
Q9RXK7
P53695
EXO1_SCHPO
Exodeoxyribonuclease I
Schizosaccharomyces
<M><G><I><K><G><L><L><G><L><L><K><P><M><Q><K><S><S><H><V><E><E><F><S><G><K><T><L><G><V><D><G><Y><V><W><L><H><K><A><V><F><T><C><A><H><E><L><A><F><N><K><E><T><D><K><Y><L><K><Y><A><I><H><Q><A><L><M><L><Q><Y><Y><G><V><K><P><L><I><V><F><D><G><G><P><L><P><C><K><A><S><T><E><Q><K><R><K><E><R><R><Q><E><A><F><E><L><G><K><K><L><W...
5'->3' double-stranded DNA exonuclease that could act in a pathway that corrects mismatched base pairs.<BOP>
P53695
Q4ZU60
GCH4_PSEU2
GTP cyclohydrolase FolE2
Pseudomonas syringae
<M><N><K><P><L><P><D><V><A><L><T><E><I><S><P><A><L><V><S><L><D><W><V><G><M><Q><G><V><E><V><P><I><R><L><A><E><A><S><I><R><H><P><V><H><A><H><V><D><L><Q><V><D><L><A><D><P><S><V><K><G><I><H><M><S><R><L><Y><R><L><L><D><G><Y><A><E><R><Q><I><V><S><P><D><T><L><A><A><L><L><E><A><M><V><E><S><H><L><D><C><H><S><S><H><A><R><L><T><L...
Converts GTP to 7,8-dihydroneopterin triphosphate.<BOP>
Q4ZU60
A6X0A5
RL11_BRUA4
50S ribosomal protein L11
Brucella
<M><A><K><K><I><A><G><Q><L><K><L><Q><V><A><A><G><A><A><N><P><S><P><P><I><G><P><A><L><G><Q><R><G><I><N><I><M><E><F><C><K><A><F><N><A><A><S><Q><E><M><E><K><G><S><P><I><P><V><V><I><T><Y><Y><Q><D><K><S><F><T><F><V><M><K><T><P><P><V><T><Y><F><L><K><K><A><A><N><L><K><S><G><S><K><T><P><G><K><A><S><A><G><T><I><S><R><D><K><V><R...
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.<BOP>
A6X0A5
Q5HRL5
RL11_STAEQ
50S ribosomal protein L11
Staphylococcus
<M><A><K><K><V><E><K><V><V><K><L><Q><I><P><A><G><K><A><N><P><A><P><P><V><G><P><A><L><G><Q><A><G><V><N><I><M><G><F><C><K><E><F><N><A><R><T><Q><E><Q><A><G><L><I><I><P><V><E><I><S><V><Y><E><D><R><S><F><T><F><I><T><K><T><P><P><A><P><V><L><L><K><K><A><A><G><V><E><K><G><S><G><E><P><N><K><T><K><V><A><T><V><T><K><D><Q><V><R><E...
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.<BOP>
Q5HRL5
Q3U2S8
HVCN1_MOUSE
Voltage sensor domain-only protein
Mus
<M><T><S><H><D><P><K><A><V><T><R><R><T><K><V><A><P><T><K><R><M><S><R><F><L><K><H><F><T><V><V><G><D><D><Y><H><T><W><N><V><N><Y><K><K><W><E><N><E><E><E><E><E><E><P><A><P><T><S><A><E><G><E><G><N><A><E><G><P><D><A><E><A><G><S><A><S><T><P><R><Q><S><L><D><F><R><S><R><L><R><K><L><F><S><S><H><R><F><Q><V><I><I><I><C><L><V><V><L...
Mediates the voltage-dependent proton permeability of excitable membranes. Forms a proton-selective channel through which protons may pass in accordance with their electrochemical gradient. Proton efflux, accompanied by membrane depolarization, facilitates acute production of reactive oxygen species in phagocytosis.<BO...
Q3U2S8
B8HD07
RS10_PSECP
30S ribosomal protein S10
Pseudarthrobacter
<M><A><G><Q><K><I><R><I><R><L><K><S><Y><D><H><E><V><I><D><V><S><A><R><K><I><V><E><T><V><T><R><A><G><A><T><V><V><G><P><V><P><L><P><T><E><K><N><V><Y><C><V><I><R><S><P><H><K><Y><K><D><S><R><E><H><F><E><M><R><T><H><K><R><L><I><D><I><I><D><P><T><P><K><A><V><D><S><L><M><R><L><D><L><P><A><D><V><N><I><E><I><K><L>
Involved in the binding of tRNA to the ribosomes.<BOP>
B8HD07
Q4R7D9
PSA7L_MACFA
Proteasome subunit alpha type-7-like
Macaca
<M><A><S><R><Y><D><R><A><I><T><V><F><S><P><D><G><H><L><F><Q><V><E><Y><A><Q><E><A><V><K><K><G><S><T><A><V><G><I><R><G><T><N><I><V><V><L><G><V><E><K><K><S><V><A><K><L><Q><D><E><R><T><V><R><K><I><C><A><L><D><D><H><V><C><M><A><F><A><G><L><T><A><D><A><R><V><V><I><N><R><A><R><V><E><C><Q><S><H><K><L><T><V><E><D><P><V><T><V><E...
Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participate...
Q4R7D9