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@@ -21,6 +21,8 @@ Accurate inference of phylogenetic trees is fundamental to evolutionary biology,
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  Illustration of predicting a phylogenetic tree using BetaInfer. Panel (a) shows the simulated “true” evolutionary dynamics, in which the ancestral sequence “AAMM” diverged along a phylogenetic tree evolving into four leaves: “ADAM”, “ADAW”, “AAM”, and “ATMMM”. Panel (b) illustrates the BetaReconstruct pipeline: (Ⅰ): unaligned protein sequences serve as input for our model; (Ⅱ): The unaligned protein sequences are concatenated into the input “sentence”, and the special token marking the start of the phylogenetic tree inference is added; (Ⅲ): Our trained model processes the input and generates the phylogenetic tree (the output); (Ⅳ): the generated phylogenetic tree. Panels (c) highlights the labeling of the taxa in the resulting tree, in which, the first protein sequence is labeled ℓ0, and the second is labeled ℓ1, and so forth.
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  ## Public models
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  **[IMPORTANT] Note on Generalization**: While we have verified the models' ability to generalize to out-of-distribution data (as detailed in the main text), performance is highest when inference is performed on data distributions similar to those used during training.
 
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  Illustration of predicting a phylogenetic tree using BetaInfer. Panel (a) shows the simulated “true” evolutionary dynamics, in which the ancestral sequence “AAMM” diverged along a phylogenetic tree evolving into four leaves: “ADAM”, “ADAW”, “AAM”, and “ATMMM”. Panel (b) illustrates the BetaReconstruct pipeline: (Ⅰ): unaligned protein sequences serve as input for our model; (Ⅱ): The unaligned protein sequences are concatenated into the input “sentence”, and the special token marking the start of the phylogenetic tree inference is added; (Ⅲ): Our trained model processes the input and generates the phylogenetic tree (the output); (Ⅳ): the generated phylogenetic tree. Panels (c) highlights the labeling of the taxa in the resulting tree, in which, the first protein sequence is labeled ℓ0, and the second is labeled ℓ1, and so forth.
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+ ## link: https://www.biorxiv.org/content/10.64898/2026.06.14.732140v1
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  ## Public models
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  **[IMPORTANT] Note on Generalization**: While we have verified the models' ability to generalize to out-of-distribution data (as detailed in the main text), performance is highest when inference is performed on data distributions similar to those used during training.