Upload cycle_70_lab_L0/exp_rl_pathb_650m_FULL_AUDIT_dapo_s2_20260506_125416/log.jsonl with huggingface_hub
Browse files
cycle_70_lab_L0/exp_rl_pathb_650m_FULL_AUDIT_dapo_s2_20260506_125416/log.jsonl
ADDED
|
@@ -0,0 +1,101 @@
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 1 |
+
{"rl_step": 1, "loss": -0.0, "mean_return": 0.0, "max_return": 0.0, "mean_motif_chained": 0.0, "gnorm": 0.0, "elapsed_s": 9.515080451965332, "cell_type": "Oli", "edit_type": "cell_type_transfer", "target_tf": "ERG", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.0, "adv_min": 0.0, "adv_max": 0.0, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.0, "comp_kd_mean": 0.0, "comp_total_mean": 0.0, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 2 |
+
{"rl_step": 5, "loss": -1.4901161193847656e-08, "mean_return": 0.2425747513771057, "max_return": 0.9702990055084229, "mean_motif_chained": 0.24257475, "gnorm": 5.960464477539063e-08, "elapsed_s": 44.728407859802246, "cell_type": "OPC", "edit_type": "promoter_retarget", "target_tf": "ASCL1", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 1.4901161193847656e-08, "adv_std": 0.9999979138374329, "adv_min": -0.49999895691871643, "adv_max": 1.4999969005584717, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.24257475, "comp_kd_mean": 0.0, "comp_total_mean": 0.24257475, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 3 |
+
{"rl_step": 10, "loss": 1.4901161193847656e-08, "mean_return": 0.24014900624752045, "max_return": 0.9605960249900818, "mean_motif_chained": 0.2401490025, "gnorm": 2.2165477275848389e-07, "elapsed_s": 88.66829299926758, "cell_type": "Ex", "edit_type": "promoter_retarget", "target_tf": "MEF2C", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": -1.4901161193847656e-08, "adv_std": 0.9999978542327881, "adv_min": -0.49999895691871643, "adv_max": 1.4999967813491821, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.2401490025, "comp_kd_mean": 0.0, "comp_total_mean": 0.2401490025, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 4 |
+
{"rl_step": 15, "loss": 4.470348358154297e-08, "mean_return": 0.3977753520011902, "max_return": 1.5911014080047607, "mean_motif_chained": 0.39777536312192247, "gnorm": 1.4901161193847656e-07, "elapsed_s": 132.9694664478302, "cell_type": "Oli", "edit_type": "promoter_retarget", "target_tf": "NKX2-2", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": -4.470348358154297e-08, "adv_std": 0.9999986886978149, "adv_min": -0.49999937415122986, "adv_max": 1.4999979734420776, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.39777536312192247, "comp_kd_mean": 0.0, "comp_total_mean": 0.39777536312192247, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 5 |
+
{"rl_step": 20, "loss": -0.0, "mean_return": 0.0, "max_return": 0.0, "mean_motif_chained": 0.0, "gnorm": 0.0, "elapsed_s": 177.1254334449768, "cell_type": "Ex", "edit_type": "cell_type_transfer", "target_tf": "SOX6", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.0, "adv_min": 0.0, "adv_max": 0.0, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.0, "comp_kd_mean": 0.0, "comp_total_mean": 0.0, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 6 |
+
{"rl_step": 25, "loss": -1.4901161193847656e-08, "mean_return": 0.1715175062417984, "max_return": 0.6860700249671936, "mean_motif_chained": 0.1715175, "gnorm": 1.4062970876693726e-07, "elapsed_s": 221.26302027702332, "cell_type": "Ex", "edit_type": "cell_type_transfer", "target_tf": "OLIG2", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 1.4901161193847656e-08, "adv_std": 0.9999970197677612, "adv_min": -0.4999985098838806, "adv_max": 1.4999955892562866, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.1715175, "comp_kd_mean": 0.0, "comp_total_mean": 0.1715175, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 7 |
+
{"rl_step": 30, "loss": -2.9802322387695312e-08, "mean_return": 0.31219369173049927, "max_return": 0.6724172234535217, "mean_motif_chained": 0.31219370324999995, "gnorm": 9.825453162193298e-08, "elapsed_s": 265.3051497936249, "cell_type": "Ex", "edit_type": "activity_boost", "target_tf": "MEF2C", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 2.9802322387695312e-08, "adv_std": 0.9999972581863403, "adv_min": -0.8609436750411987, "adv_max": 0.9933966398239136, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.31219370324999995, "comp_kd_mean": 0.0, "comp_total_mean": 0.31219370324999995, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 8 |
+
{"rl_step": 35, "loss": -0.0, "mean_return": 0.14264850318431854, "max_return": 0.5705940127372742, "mean_motif_chained": 0.142648507485, "gnorm": 1.8998980522155762e-07, "elapsed_s": 309.5000557899475, "cell_type": "OPC", "edit_type": "cell_type_transfer", "target_tf": "SOX6", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.9999964237213135, "adv_min": -0.49999821186065674, "adv_max": 1.4999946355819702, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.142648507485, "comp_kd_mean": 0.0, "comp_total_mean": 0.142648507485, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 9 |
+
{"rl_step": 40, "loss": -0.0, "mean_return": 0.1412220150232315, "max_return": 0.564888060092926, "mean_motif_chained": 0.14122202241015, "gnorm": 2.384185791015625e-07, "elapsed_s": 353.81137204170227, "cell_type": "Ex", "edit_type": "promoter_retarget", "target_tf": "NEUROD2", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.9999964237213135, "adv_min": -0.49999821186065674, "adv_max": 1.4999946355819702, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.14122202241015, "comp_kd_mean": 0.0, "comp_total_mean": 0.14122202241015, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 10 |
+
{"rl_step": 45, "loss": -0.0, "mean_return": 0.0, "max_return": 0.0, "mean_motif_chained": 0.0, "gnorm": 0.0, "elapsed_s": 397.8401393890381, "cell_type": "Ex", "edit_type": "promoter_retarget", "target_tf": "NEUROD2", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.0, "adv_min": 0.0, "adv_max": 0.0, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.0, "comp_kd_mean": 0.0, "comp_total_mean": 0.0, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 11 |
+
{"rl_step": 50, "loss": 2.9802322387695312e-08, "mean_return": 0.34825000166893005, "max_return": 0.699999988079071, "mean_motif_chained": 0.34824999999999995, "gnorm": 1.1641532182693481e-07, "elapsed_s": 442.0781376361847, "cell_type": "In", "edit_type": "activity_boost", "target_tf": "DLX2", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": -2.9802322387695312e-08, "adv_std": 0.9999974966049194, "adv_min": -0.8660014271736145, "adv_max": 0.874704897403717, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.34824999999999995, "comp_kd_mean": 0.0, "comp_total_mean": 0.34824999999999995, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 12 |
+
{"rl_step": 55, "loss": -0.0, "mean_return": 0.14264850318431854, "max_return": 0.5705940127372742, "mean_motif_chained": 0.142648507485, "gnorm": 2.5331974029541016e-07, "elapsed_s": 486.4537401199341, "cell_type": "Ast", "edit_type": "activity_boost", "target_tf": "AP1", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.9999964237213135, "adv_min": -0.49999821186065674, "adv_max": 1.4999946355819702, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.142648507485, "comp_kd_mean": 0.0, "comp_total_mean": 0.142648507485, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 13 |
+
{"rl_step": 60, "loss": -0.0, "mean_return": 0.0, "max_return": 0.0, "mean_motif_chained": 0.0, "gnorm": 0.0, "elapsed_s": 530.3697800636292, "cell_type": "Oli", "edit_type": "cell_type_transfer", "target_tf": "NEUROD2", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.0, "adv_min": 0.0, "adv_max": 0.0, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.0, "comp_kd_mean": 0.0, "comp_total_mean": 0.0, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 14 |
+
{"rl_step": 65, "loss": -0.0, "mean_return": 0.0, "max_return": 0.0, "mean_motif_chained": 0.0, "gnorm": 0.0, "elapsed_s": 574.694858789444, "cell_type": "Oli", "edit_type": "activity_boost", "target_tf": "MYRF", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.0, "adv_min": 0.0, "adv_max": 0.0, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.0, "comp_kd_mean": 0.0, "comp_total_mean": 0.0, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 15 |
+
{"rl_step": 70, "loss": 1.4901161193847656e-08, "mean_return": 0.18829603493213654, "max_return": 0.7531841397285461, "mean_motif_chained": 0.1882960298802, "gnorm": 8.009374141693115e-08, "elapsed_s": 618.9283590316772, "cell_type": "Mic", "edit_type": "cell_type_transfer", "target_tf": "SOX6", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": -1.4901161193847656e-08, "adv_std": 0.9999972581863403, "adv_min": -0.49999865889549255, "adv_max": 1.4999959468841553, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.1882960298802, "comp_kd_mean": 0.0, "comp_total_mean": 0.1882960298802, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 16 |
+
{"rl_step": 75, "loss": -0.0, "mean_return": 0.1940598040819168, "max_return": 0.7762392163276672, "mean_motif_chained": 0.1940598, "gnorm": 5.51808625459671e-08, "elapsed_s": 662.8130843639374, "cell_type": "Mic", "edit_type": "cell_type_transfer", "target_tf": "MYRF", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.9999973773956299, "adv_min": -0.49999868869781494, "adv_max": 1.4999960660934448, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.1940598, "comp_kd_mean": 0.0, "comp_total_mean": 0.1940598, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 17 |
+
{"rl_step": 80, "loss": 2.9802322387695312e-08, "mean_return": 0.40862005949020386, "max_return": 0.9414801597595215, "mean_motif_chained": 0.40862003735025, "gnorm": 1.019798219203949e-07, "elapsed_s": 706.7993285655975, "cell_type": "Ex", "edit_type": "cell_type_transfer", "target_tf": "MYRF", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": -2.9802322387695312e-08, "adv_std": 0.9999978542327881, "adv_min": -0.8466768860816956, "adv_max": 1.104107141494751, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.40862003735025, "comp_kd_mean": 0.0, "comp_total_mean": 0.40862003735025, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 18 |
+
{"rl_step": 85, "loss": -0.0, "mean_return": 0.0, "max_return": 0.0, "mean_motif_chained": 0.0, "gnorm": 0.0, "elapsed_s": 750.9144184589386, "cell_type": "Oli", "edit_type": "activity_boost", "target_tf": "OLIG2", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.0, "adv_min": 0.0, "adv_max": 0.0, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.0, "comp_kd_mean": 0.0, "comp_total_mean": 0.0, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 19 |
+
{"rl_step": 90, "loss": 1.4901161193847656e-08, "mean_return": 0.17499999701976776, "max_return": 0.699999988079071, "mean_motif_chained": 0.175, "gnorm": 1.2945383787155151e-07, "elapsed_s": 794.6889610290527, "cell_type": "In", "edit_type": "activity_boost", "target_tf": "SOX6", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": -1.4901161193847656e-08, "adv_std": 0.9999970197677612, "adv_min": -0.499998539686203, "adv_max": 1.4999955892562866, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.175, "comp_kd_mean": 0.0, "comp_total_mean": 0.175, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 20 |
+
{"rl_step": 95, "loss": -1.4901161193847656e-08, "mean_return": 0.8288717269897461, "max_return": 1.3316550254821777, "mean_motif_chained": 0.8288717142324464, "gnorm": 1.2293457984924316e-07, "elapsed_s": 838.8063206672668, "cell_type": "End", "edit_type": "promoter_retarget", "target_tf": "KLF2", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 1.4901161193847656e-08, "adv_std": 0.9999983906745911, "adv_min": -1.3073877096176147, "adv_max": 0.793045163154602, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.8288717142324464, "comp_kd_mean": 0.0, "comp_total_mean": 0.8288717142324464, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 21 |
+
{"rl_step": 100, "loss": -4.470348358154297e-08, "mean_return": 0.5473381280899048, "max_return": 1.607173204421997, "mean_motif_chained": 0.54733814608275, "gnorm": 1.3783574104309082e-07, "elapsed_s": 882.3406519889832, "cell_type": "OPC", "edit_type": "cell_type_transfer", "target_tf": "FLI1", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 4.470348358154297e-08, "adv_std": 0.9999986886978149, "adv_min": -0.7220955491065979, "adv_max": 1.3982256650924683, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.54733814608275, "comp_kd_mean": 0.0, "comp_total_mean": 0.54733814608275, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 22 |
+
{"rl_step": 105, "loss": -0.0, "mean_return": 0.0, "max_return": 0.0, "mean_motif_chained": 0.0, "gnorm": 0.0, "elapsed_s": 965.9969334602356, "cell_type": "Ex", "edit_type": "activity_boost", "target_tf": "TBR1", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.0, "adv_min": 0.0, "adv_max": 0.0, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.0, "comp_kd_mean": 0.0, "comp_total_mean": 0.0, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 23 |
+
{"rl_step": 110, "loss": -0.0, "mean_return": 0.0, "max_return": 0.0, "mean_motif_chained": 0.0, "gnorm": 0.0, "elapsed_s": 1013.5447916984558, "cell_type": "Mic", "edit_type": "activity_boost", "target_tf": "CEBPA", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.0, "adv_min": 0.0, "adv_max": 0.0, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.0, "comp_kd_mean": 0.0, "comp_total_mean": 0.0, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 24 |
+
{"rl_step": 115, "loss": -0.0, "mean_return": 0.0, "max_return": 0.0, "mean_motif_chained": 0.0, "gnorm": 0.0, "elapsed_s": 1057.350860118866, "cell_type": "Ast", "edit_type": "promoter_retarget", "target_tf": "AP1", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.0, "adv_min": 0.0, "adv_max": 0.0, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.0, "comp_kd_mean": 0.0, "comp_total_mean": 0.0, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 25 |
+
{"rl_step": 120, "loss": -0.0, "mean_return": 0.0, "max_return": 0.0, "mean_motif_chained": 0.0, "gnorm": 0.0, "elapsed_s": 1106.6198556423187, "cell_type": "Ast", "edit_type": "cell_type_transfer", "target_tf": "TBR1", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.0, "adv_min": 0.0, "adv_max": 0.0, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.0, "comp_kd_mean": 0.0, "comp_total_mean": 0.0, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 26 |
+
{"rl_step": 125, "loss": -0.0, "mean_return": 0.0, "max_return": 0.0, "mean_motif_chained": 0.0, "gnorm": 0.0, "elapsed_s": 1150.346553325653, "cell_type": "Mic", "edit_type": "activity_boost", "target_tf": "CEBPA", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.0, "adv_min": 0.0, "adv_max": 0.0, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.0, "comp_kd_mean": 0.0, "comp_total_mean": 0.0, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 27 |
+
{"rl_step": 130, "loss": 1.4901161193847656e-08, "mean_return": 0.148499995470047, "max_return": 0.593999981880188, "mean_motif_chained": 0.1485, "gnorm": 2.086162567138672e-07, "elapsed_s": 1205.1176941394806, "cell_type": "Ast", "edit_type": "promoter_retarget", "target_tf": "AP1", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": -1.4901161193847656e-08, "adv_std": 0.999996542930603, "adv_min": -0.4999983012676239, "adv_max": 1.4999948740005493, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.1485, "comp_kd_mean": 0.0, "comp_total_mean": 0.1485, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 28 |
+
{"rl_step": 135, "loss": -0.0, "mean_return": 0.0, "max_return": 0.0, "mean_motif_chained": 0.0, "gnorm": 0.0, "elapsed_s": 1248.9154877662659, "cell_type": "Ast", "edit_type": "promoter_retarget", "target_tf": "STAT3", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.0, "adv_min": 0.0, "adv_max": 0.0, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.0, "comp_kd_mean": 0.0, "comp_total_mean": 0.0, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 29 |
+
{"rl_step": 140, "loss": -5.960464477539063e-08, "mean_return": 0.31177401542663574, "max_return": 0.6590360999107361, "mean_motif_chained": 0.31177402614517497, "gnorm": 5.51808625459671e-08, "elapsed_s": 1960.4128680229187, "cell_type": "Ex", "edit_type": "promoter_retarget", "target_tf": "TBR1", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 5.960464477539063e-08, "adv_std": 0.9999971985816956, "adv_min": -0.863231360912323, "adv_max": 0.9614897966384888, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.31177402614517497, "comp_kd_mean": 0.0, "comp_total_mean": 0.31177402614517497, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 30 |
+
{"rl_step": 145, "loss": 1.4901161193847656e-08, "mean_return": 0.40517234802246094, "max_return": 1.6206893920898438, "mean_motif_chained": 0.40517236235025, "gnorm": 2.123415470123291e-07, "elapsed_s": 2004.1561014652252, "cell_type": "Oli", "edit_type": "cell_type_transfer", "target_tf": "ASCL1", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": -1.4901161193847656e-08, "adv_std": 0.9999986886978149, "adv_min": -0.49999937415122986, "adv_max": 1.4999980926513672, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.40517236235025, "comp_kd_mean": 0.0, "comp_total_mean": 0.40517236235025, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 31 |
+
{"rl_step": 150, "loss": -0.0, "mean_return": 0.0, "max_return": 0.0, "mean_motif_chained": 0.0, "gnorm": 0.0, "elapsed_s": 2047.5401856899261, "cell_type": "Ex", "edit_type": "activity_boost", "target_tf": "RORB", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.0, "adv_min": 0.0, "adv_max": 0.0, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.0, "comp_kd_mean": 0.0, "comp_total_mean": 0.0, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 32 |
+
{"rl_step": 155, "loss": -0.0, "mean_return": 0.0, "max_return": 0.0, "mean_motif_chained": 0.0, "gnorm": 0.0, "elapsed_s": 2099.340835571289, "cell_type": "Ex", "edit_type": "promoter_retarget", "target_tf": "RORB", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.0, "adv_min": 0.0, "adv_max": 0.0, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.0, "comp_kd_mean": 0.0, "comp_total_mean": 0.0, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 33 |
+
{"rl_step": 160, "loss": -0.0, "mean_return": 0.0, "max_return": 0.0, "mean_motif_chained": 0.0, "gnorm": 0.0, "elapsed_s": 2143.0385868549347, "cell_type": "Ast", "edit_type": "activity_boost", "target_tf": "NFIA", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.0, "adv_min": 0.0, "adv_max": 0.0, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.0, "comp_kd_mean": 0.0, "comp_total_mean": 0.0, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 34 |
+
{"rl_step": 165, "loss": -0.0, "mean_return": 0.0, "max_return": 0.0, "mean_motif_chained": 0.0, "gnorm": 0.0, "elapsed_s": 2196.60577249527, "cell_type": "OPC", "edit_type": "cell_type_transfer", "target_tf": "SPI1", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.0, "adv_min": 0.0, "adv_max": 0.0, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.0, "comp_kd_mean": 0.0, "comp_total_mean": 0.0, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 35 |
+
{"rl_step": 170, "loss": -0.0, "mean_return": 0.16311143338680267, "max_return": 0.6524457335472107, "mean_motif_chained": 0.16311143588372323, "gnorm": 3.4831464290618896e-07, "elapsed_s": 2240.3491489887238, "cell_type": "In", "edit_type": "promoter_retarget", "target_tf": "DLX2", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.9999969005584717, "adv_min": -0.49999845027923584, "adv_max": 1.4999953508377075, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.16311143588372323, "comp_kd_mean": 0.0, "comp_total_mean": 0.16311143588372323, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 36 |
+
{"rl_step": 175, "loss": -0.0, "mean_return": 0.0, "max_return": 0.0, "mean_motif_chained": 0.0, "gnorm": 0.0, "elapsed_s": 2290.4167487621307, "cell_type": "In", "edit_type": "promoter_retarget", "target_tf": "LHX6", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.0, "adv_min": 0.0, "adv_max": 0.0, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.0, "comp_kd_mean": 0.0, "comp_total_mean": 0.0, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 37 |
+
{"rl_step": 180, "loss": -0.0, "mean_return": 0.0, "max_return": 0.0, "mean_motif_chained": 0.0, "gnorm": 0.0, "elapsed_s": 2333.9287939071655, "cell_type": "Ex", "edit_type": "cell_type_transfer", "target_tf": "RUNX1", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.0, "adv_min": 0.0, "adv_max": 0.0, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.0, "comp_kd_mean": 0.0, "comp_total_mean": 0.0, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 38 |
+
{"rl_step": 185, "loss": -0.0, "mean_return": 0.0, "max_return": 0.0, "mean_motif_chained": 0.0, "gnorm": 0.0, "elapsed_s": 2651.5193812847137, "cell_type": "Mic", "edit_type": "activity_boost", "target_tf": "RUNX1", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.0, "adv_min": 0.0, "adv_max": 0.0, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.0, "comp_kd_mean": 0.0, "comp_total_mean": 0.0, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 39 |
+
{"rl_step": 190, "loss": 2.9802322387695312e-08, "mean_return": 0.4082533121109009, "max_return": 0.9605960249900818, "mean_motif_chained": 0.40825330424999995, "gnorm": 7.450580596923828e-08, "elapsed_s": 2695.226603269577, "cell_type": "Oli", "edit_type": "cell_type_transfer", "target_tf": "RUNX1", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": -2.9802322387695312e-08, "adv_std": 0.9999979138374329, "adv_min": -0.8402518630027771, "adv_max": 1.1368112564086914, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.40825330424999995, "comp_kd_mean": 0.0, "comp_total_mean": 0.40825330424999995, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 40 |
+
{"rl_step": 195, "loss": 1.4901161193847656e-08, "mean_return": 0.24014900624752045, "max_return": 0.9605960249900818, "mean_motif_chained": 0.2401490025, "gnorm": 4.209578037261963e-07, "elapsed_s": 2738.8036019802094, "cell_type": "Ex", "edit_type": "cell_type_transfer", "target_tf": "AP1", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": -1.4901161193847656e-08, "adv_std": 0.9999978542327881, "adv_min": -0.49999895691871643, "adv_max": 1.4999967813491821, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.2401490025, "comp_kd_mean": 0.0, "comp_total_mean": 0.2401490025, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 41 |
+
{"rl_step": 200, "loss": -5.960464477539063e-08, "mean_return": 0.4034743309020996, "max_return": 0.9414801597595215, "mean_motif_chained": 0.40347433910025, "gnorm": 9.685754776000977e-08, "elapsed_s": 2782.4961495399475, "cell_type": "Ex", "edit_type": "activity_boost", "target_tf": "NEUROD2", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 5.960464477539063e-08, "adv_std": 0.9999978542327881, "adv_min": -0.8429121971130371, "adv_max": 1.1239666938781738, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.40347433910025, "comp_kd_mean": 0.0, "comp_total_mean": 0.40347433910025, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 42 |
+
{"rl_step": 205, "loss": -5.960464477539063e-08, "mean_return": 0.552117109298706, "max_return": 0.9605960249900818, "mean_motif_chained": 0.5521171112325, "gnorm": 1.1362135410308838e-07, "elapsed_s": 2830.319365501404, "cell_type": "Ex", "edit_type": "cell_type_transfer", "target_tf": "SOX9", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 5.960464477539063e-08, "adv_std": 0.9999974966049194, "adv_min": -1.3724606037139893, "adv_max": 1.0154027938842773, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.5521171112325, "comp_kd_mean": 0.0, "comp_total_mean": 0.5521171112325, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 43 |
+
{"rl_step": 210, "loss": -0.0, "mean_return": 0.16311143338680267, "max_return": 0.6524457335472107, "mean_motif_chained": 0.16311143588372323, "gnorm": 5.587935447692871e-08, "elapsed_s": 2873.869858264923, "cell_type": "Oli", "edit_type": "promoter_retarget", "target_tf": "MYRF", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.9999969005584717, "adv_min": -0.49999845027923584, "adv_max": 1.4999953508377075, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.16311143588372323, "comp_kd_mean": 0.0, "comp_total_mean": 0.16311143588372323, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 44 |
+
{"rl_step": 215, "loss": -0.0, "mean_return": 0.0, "max_return": 0.0, "mean_motif_chained": 0.0, "gnorm": 0.0, "elapsed_s": 2917.60986995697, "cell_type": "OPC", "edit_type": "promoter_retarget", "target_tf": "ASCL1", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.0, "adv_min": 0.0, "adv_max": 0.0, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.0, "comp_kd_mean": 0.0, "comp_total_mean": 0.0, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 45 |
+
{"rl_step": 220, "loss": -0.0, "mean_return": 0.23774750530719757, "max_return": 0.9509900212287903, "mean_motif_chained": 0.23774751247499998, "gnorm": 7.310882210731506e-08, "elapsed_s": 2961.1599531173706, "cell_type": "Oli", "edit_type": "cell_type_transfer", "target_tf": "SOX10", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.9999978542327881, "adv_min": -0.49999892711639404, "adv_max": 1.4999967813491821, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.23774751247499998, "comp_kd_mean": 0.0, "comp_total_mean": 0.23774751247499998, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 46 |
+
{"rl_step": 225, "loss": 2.9802322387695312e-08, "mean_return": 0.23301634192466736, "max_return": 0.9320653676986694, "mean_motif_chained": 0.23301633697674748, "gnorm": 6.891787052154541e-08, "elapsed_s": 3005.020259618759, "cell_type": "Oli", "edit_type": "cell_type_transfer", "target_tf": "TBR1", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": -2.9802322387695312e-08, "adv_std": 0.9999977350234985, "adv_min": -0.49999892711639404, "adv_max": 1.4999966621398926, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.23301633697674748, "comp_kd_mean": 0.0, "comp_total_mean": 0.23301633697674748, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 47 |
+
{"rl_step": 230, "loss": -0.0, "mean_return": 0.0, "max_return": 0.0, "mean_motif_chained": 0.0, "gnorm": 0.0, "elapsed_s": 3048.4264104366302, "cell_type": "Mic", "edit_type": "promoter_retarget", "target_tf": "IRF8", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.0, "adv_min": 0.0, "adv_max": 0.0, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.0, "comp_kd_mean": 0.0, "comp_total_mean": 0.0, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 48 |
+
{"rl_step": 235, "loss": 1.4901161193847656e-08, "mean_return": 0.148499995470047, "max_return": 0.593999981880188, "mean_motif_chained": 0.1485, "gnorm": 2.8870999813079834e-07, "elapsed_s": 3092.2498772144318, "cell_type": "Ex", "edit_type": "cell_type_transfer", "target_tf": "SOX9", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": -1.4901161193847656e-08, "adv_std": 0.999996542930603, "adv_min": -0.4999983012676239, "adv_max": 1.4999948740005493, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.1485, "comp_kd_mean": 0.0, "comp_total_mean": 0.1485, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 49 |
+
{"rl_step": 240, "loss": -0.0, "mean_return": 0.23537003993988037, "max_return": 0.9414801597595215, "mean_motif_chained": 0.23537003735025, "gnorm": 1.6763806343078613e-07, "elapsed_s": 3135.7948751449585, "cell_type": "In", "edit_type": "cell_type_transfer", "target_tf": "ASCL1", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.9999978542327881, "adv_min": -0.49999892711639404, "adv_max": 1.4999967813491821, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.23537003735025, "comp_kd_mean": 0.0, "comp_total_mean": 0.23537003735025, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 50 |
+
{"rl_step": 245, "loss": -0.0, "mean_return": 0.0, "max_return": 0.0, "mean_motif_chained": 0.0, "gnorm": 0.0, "elapsed_s": 3179.5443744659424, "cell_type": "Oli", "edit_type": "cell_type_transfer", "target_tf": "SOX17", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.0, "adv_min": 0.0, "adv_max": 0.0, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.0, "comp_kd_mean": 0.0, "comp_total_mean": 0.0, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 51 |
+
{"rl_step": 250, "loss": 1.4901161193847656e-08, "mean_return": 0.148499995470047, "max_return": 0.593999981880188, "mean_motif_chained": 0.1485, "gnorm": 1.0943040251731873e-07, "elapsed_s": 3223.083422899246, "cell_type": "Ex", "edit_type": "promoter_retarget", "target_tf": "MEF2C", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": -1.4901161193847656e-08, "adv_std": 0.999996542930603, "adv_min": -0.4999983012676239, "adv_max": 1.4999948740005493, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.1485, "comp_kd_mean": 0.0, "comp_total_mean": 0.1485, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 52 |
+
{"rl_step": 255, "loss": -0.0, "mean_return": 0.0, "max_return": 0.0, "mean_motif_chained": 0.0, "gnorm": 0.0, "elapsed_s": 3266.86345911026, "cell_type": "Mic", "edit_type": "cell_type_transfer", "target_tf": "SOX6", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.0, "adv_min": 0.0, "adv_max": 0.0, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.0, "comp_kd_mean": 0.0, "comp_total_mean": 0.0, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 53 |
+
{"rl_step": 260, "loss": -0.0, "mean_return": 0.0, "max_return": 0.0, "mean_motif_chained": 0.0, "gnorm": 0.0, "elapsed_s": 3310.4066722393036, "cell_type": "Ex", "edit_type": "cell_type_transfer", "target_tf": "MYRF", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.0, "adv_min": 0.0, "adv_max": 0.0, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.0, "comp_kd_mean": 0.0, "comp_total_mean": 0.0, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 54 |
+
{"rl_step": 265, "loss": -0.0, "mean_return": 0.0, "max_return": 0.0, "mean_motif_chained": 0.0, "gnorm": 0.0, "elapsed_s": 3354.2449221611023, "cell_type": "Ast", "edit_type": "activity_boost", "target_tf": "AP1", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.0, "adv_min": 0.0, "adv_max": 0.0, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.0, "comp_kd_mean": 0.0, "comp_total_mean": 0.0, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 55 |
+
{"rl_step": 270, "loss": 1.4901161193847656e-08, "mean_return": 0.1732500046491623, "max_return": 0.6930000185966492, "mean_motif_chained": 0.17325, "gnorm": 9.639188647270203e-08, "elapsed_s": 3397.668113231659, "cell_type": "Oli", "edit_type": "promoter_retarget", "target_tf": "MYRF", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": -1.4901161193847656e-08, "adv_std": 0.9999970197677612, "adv_min": -0.499998539686203, "adv_max": 1.4999955892562866, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.17325, "comp_kd_mean": 0.0, "comp_total_mean": 0.17325, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 56 |
+
{"rl_step": 275, "loss": -1.4901161193847656e-08, "mean_return": 0.1715175062417984, "max_return": 0.6860700249671936, "mean_motif_chained": 0.1715175, "gnorm": 1.7601996660232544e-07, "elapsed_s": 3441.5164062976837, "cell_type": "OPC", "edit_type": "promoter_retarget", "target_tf": "SOX10", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 1.4901161193847656e-08, "adv_std": 0.9999970197677612, "adv_min": -0.4999985098838806, "adv_max": 1.4999955892562866, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.1715175, "comp_kd_mean": 0.0, "comp_total_mean": 0.1715175, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 57 |
+
{"rl_step": 280, "loss": -0.0, "mean_return": 0.0, "max_return": 0.0, "mean_motif_chained": 0.0, "gnorm": 0.0, "elapsed_s": 3485.3171832561493, "cell_type": "Ast", "edit_type": "cell_type_transfer", "target_tf": "DLX1", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.0, "adv_min": 0.0, "adv_max": 0.0, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.0, "comp_kd_mean": 0.0, "comp_total_mean": 0.0, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 58 |
+
{"rl_step": 285, "loss": -0.0, "mean_return": 0.33620861172676086, "max_return": 0.6724172234535217, "mean_motif_chained": 0.3362086035, "gnorm": 3.501772880554199e-07, "elapsed_s": 3528.856263399124, "cell_type": "Ex", "edit_type": "cell_type_transfer", "target_tf": "RUNX1", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.9999973773956299, "adv_min": -0.8660231232643127, "adv_max": 0.8660231232643127, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.3362086035, "comp_kd_mean": 0.0, "comp_total_mean": 0.3362086035, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 59 |
+
{"rl_step": 290, "loss": 1.4901161193847656e-08, "mean_return": 0.148499995470047, "max_return": 0.593999981880188, "mean_motif_chained": 0.1485, "gnorm": 3.8743019104003906e-07, "elapsed_s": 3572.56112575531, "cell_type": "Ast", "edit_type": "promoter_retarget", "target_tf": "AP1", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": -1.4901161193847656e-08, "adv_std": 0.999996542930603, "adv_min": -0.4999983012676239, "adv_max": 1.4999948740005493, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.1485, "comp_kd_mean": 0.0, "comp_total_mean": 0.1485, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 60 |
+
{"rl_step": 295, "loss": 1.4901161193847656e-08, "mean_return": 0.24014900624752045, "max_return": 0.9605960249900818, "mean_motif_chained": 0.2401490025, "gnorm": 1.0151416063308716e-07, "elapsed_s": 3616.301530122757, "cell_type": "Ex", "edit_type": "promoter_retarget", "target_tf": "TBR1", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": -1.4901161193847656e-08, "adv_std": 0.9999978542327881, "adv_min": -0.49999895691871643, "adv_max": 1.4999967813491821, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.2401490025, "comp_kd_mean": 0.0, "comp_total_mean": 0.2401490025, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 61 |
+
{"rl_step": 300, "loss": -0.0, "mean_return": 0.0, "max_return": 0.0, "mean_motif_chained": 0.0, "gnorm": 0.0, "elapsed_s": 3664.2412638664246, "cell_type": "Mic", "edit_type": "activity_boost", "target_tf": "CEBPA", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.0, "adv_min": 0.0, "adv_max": 0.0, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.0, "comp_kd_mean": 0.0, "comp_total_mean": 0.0, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 62 |
+
{"rl_step": 305, "loss": -0.0, "mean_return": 0.3312157392501831, "max_return": 0.6724172234535217, "mean_motif_chained": 0.33121573763372325, "gnorm": 1.6205012798309326e-07, "elapsed_s": 3750.4579226970673, "cell_type": "OPC", "edit_type": "activity_boost", "target_tf": "ASCL1", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.9999973177909851, "adv_min": -0.8658263683319092, "adv_max": 0.8919299840927124, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.33121573763372325, "comp_kd_mean": 0.0, "comp_total_mean": 0.33121573763372325, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 63 |
+
{"rl_step": 310, "loss": 2.9802322387695312e-08, "mean_return": 0.23301634192466736, "max_return": 0.9320653676986694, "mean_motif_chained": 0.23301633697674748, "gnorm": 7.078051567077637e-08, "elapsed_s": 3796.6213643550873, "cell_type": "In", "edit_type": "promoter_retarget", "target_tf": "DLX1", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": -2.9802322387695312e-08, "adv_std": 0.9999977350234985, "adv_min": -0.49999892711639404, "adv_max": 1.4999966621398926, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.23301633697674748, "comp_kd_mean": 0.0, "comp_total_mean": 0.23301633697674748, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 64 |
+
{"rl_step": 315, "loss": -0.0, "mean_return": 0.23774750530719757, "max_return": 0.9509900212287903, "mean_motif_chained": 0.23774751247499998, "gnorm": 1.4994293451309204e-07, "elapsed_s": 3846.2312977313995, "cell_type": "Ex", "edit_type": "cell_type_transfer", "target_tf": "NKX2-2", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.9999978542327881, "adv_min": -0.49999892711639404, "adv_max": 1.4999967813491821, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.23774751247499998, "comp_kd_mean": 0.0, "comp_total_mean": 0.23774751247499998, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 65 |
+
{"rl_step": 320, "loss": -1.4901161193847656e-08, "mean_return": 0.16980232298374176, "max_return": 0.679209291934967, "mean_motif_chained": 0.169802325, "gnorm": 1.601874828338623e-07, "elapsed_s": 3891.6132974624634, "cell_type": "Ex", "edit_type": "cell_type_transfer", "target_tf": "NFIA", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 1.4901161193847656e-08, "adv_std": 0.9999970197677612, "adv_min": -0.4999985098838806, "adv_max": 1.4999955892562866, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.169802325, "comp_kd_mean": 0.0, "comp_total_mean": 0.169802325, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 66 |
+
{"rl_step": 325, "loss": -0.0, "mean_return": 0.4851740002632141, "max_return": 0.9800999760627747, "mean_motif_chained": 0.4851740025, "gnorm": 2.3655593395233154e-07, "elapsed_s": 3937.6942896842957, "cell_type": "In", "edit_type": "promoter_retarget", "target_tf": "SOX6", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.9999982118606567, "adv_min": -0.8659363985061646, "adv_max": 0.8833417296409607, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.4851740025, "comp_kd_mean": 0.0, "comp_total_mean": 0.4851740025, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 67 |
+
{"rl_step": 330, "loss": -0.0, "mean_return": 0.0, "max_return": 0.0, "mean_motif_chained": 0.0, "gnorm": 0.0, "elapsed_s": 4654.325088262558, "cell_type": "Mic", "edit_type": "promoter_retarget", "target_tf": "IRF8", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.0, "adv_min": 0.0, "adv_max": 0.0, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.0, "comp_kd_mean": 0.0, "comp_total_mean": 0.0, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 68 |
+
{"rl_step": 335, "loss": -0.0, "mean_return": 0.0, "max_return": 0.0, "mean_motif_chained": 0.0, "gnorm": 0.0, "elapsed_s": 4696.596472024918, "cell_type": "Ex", "edit_type": "promoter_retarget", "target_tf": "TBR1", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.0, "adv_min": 0.0, "adv_max": 0.0, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.0, "comp_kd_mean": 0.0, "comp_total_mean": 0.0, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 69 |
+
{"rl_step": 340, "loss": -0.0, "mean_return": 0.5882469415664673, "max_return": 1.5845110416412354, "mean_motif_chained": 0.5882469748604706, "gnorm": 7.031485438346863e-08, "elapsed_s": 4744.091912984848, "cell_type": "Mic", "edit_type": "cell_type_transfer", "target_tf": "MEF2C", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.9999986886978149, "adv_min": -0.7775399684906006, "adv_max": 1.316853642463684, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.5882469748604706, "comp_kd_mean": 0.0, "comp_total_mean": 0.5882469748604706, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 70 |
+
{"rl_step": 345, "loss": -0.0, "mean_return": 0.32622286677360535, "max_return": 0.6524457335472107, "mean_motif_chained": 0.32622287176744647, "gnorm": 1.0058283805847168e-07, "elapsed_s": 4786.271197080612, "cell_type": "Oli", "edit_type": "cell_type_transfer", "target_tf": "CEBPA", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.9999972581863403, "adv_min": -0.866023063659668, "adv_max": 0.866023063659668, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.32622287176744647, "comp_kd_mean": 0.0, "comp_total_mean": 0.32622287176744647, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 71 |
+
{"rl_step": 350, "loss": -1.4901161193847656e-08, "mean_return": 0.1715175062417984, "max_return": 0.6860700249671936, "mean_motif_chained": 0.1715175, "gnorm": 1.150183379650116e-07, "elapsed_s": 4836.851412057877, "cell_type": "OPC", "edit_type": "activity_boost", "target_tf": "OLIG2", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 1.4901161193847656e-08, "adv_std": 0.9999970197677612, "adv_min": -0.4999985098838806, "adv_max": 1.4999955892562866, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.1715175, "comp_kd_mean": 0.0, "comp_total_mean": 0.1715175, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 72 |
+
{"rl_step": 355, "loss": 1.4901161193847656e-08, "mean_return": 0.1732500046491623, "max_return": 0.6930000185966492, "mean_motif_chained": 0.17325, "gnorm": 2.0489096641540527e-07, "elapsed_s": 4879.053933382034, "cell_type": "Oli", "edit_type": "cell_type_transfer", "target_tf": "CEBPA", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": -1.4901161193847656e-08, "adv_std": 0.9999970197677612, "adv_min": -0.499998539686203, "adv_max": 1.4999955892562866, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.17325, "comp_kd_mean": 0.0, "comp_total_mean": 0.17325, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 73 |
+
{"rl_step": 360, "loss": -0.0, "mean_return": 0.0, "max_return": 0.0, "mean_motif_chained": 0.0, "gnorm": 0.0, "elapsed_s": 4930.574341058731, "cell_type": "In", "edit_type": "cell_type_transfer", "target_tf": "AP1", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.0, "adv_min": 0.0, "adv_max": 0.0, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.0, "comp_kd_mean": 0.0, "comp_total_mean": 0.0, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 74 |
+
{"rl_step": 365, "loss": -0.0, "mean_return": 0.0, "max_return": 0.0, "mean_motif_chained": 0.0, "gnorm": 0.0, "elapsed_s": 4972.822981595993, "cell_type": "Ex", "edit_type": "cell_type_transfer", "target_tf": "SOX10", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.0, "adv_min": 0.0, "adv_max": 0.0, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.0, "comp_kd_mean": 0.0, "comp_total_mean": 0.0, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 75 |
+
{"rl_step": 370, "loss": -0.0, "mean_return": 0.0, "max_return": 0.0, "mean_motif_chained": 0.0, "gnorm": 0.0, "elapsed_s": 5026.088941335678, "cell_type": "Ast", "edit_type": "activity_boost", "target_tf": "NFIA", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.0, "adv_min": 0.0, "adv_max": 0.0, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.0, "comp_kd_mean": 0.0, "comp_total_mean": 0.0, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 76 |
+
{"rl_step": 375, "loss": 2.9802322387695312e-08, "mean_return": 0.41339901089668274, "max_return": 0.9605960249900818, "mean_motif_chained": 0.41339900249999995, "gnorm": 4.172325134277344e-07, "elapsed_s": 5068.251387119293, "cell_type": "OPC", "edit_type": "promoter_retarget", "target_tf": "SOX10", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": -2.9802322387695312e-08, "adv_std": 0.9999978542327881, "adv_min": -0.8441979885101318, "adv_max": 1.1174254417419434, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.41339900249999995, "comp_kd_mean": 0.0, "comp_total_mean": 0.41339900249999995, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 77 |
+
{"rl_step": 380, "loss": -0.0, "mean_return": 0.0, "max_return": 0.0, "mean_motif_chained": 0.0, "gnorm": 0.0, "elapsed_s": 5694.686364412308, "cell_type": "In", "edit_type": "activity_boost", "target_tf": "SOX6", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.0, "adv_min": 0.0, "adv_max": 0.0, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.0, "comp_kd_mean": 0.0, "comp_total_mean": 0.0, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 78 |
+
{"rl_step": 385, "loss": 2.9802322387695312e-08, "mean_return": 0.5611221790313721, "max_return": 1.4988363981246948, "mean_motif_chained": 0.561122169042996, "gnorm": 1.1920928955078125e-07, "elapsed_s": 5736.808020830154, "cell_type": "Mic", "edit_type": "activity_boost", "target_tf": "IRF8", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": -2.9802322387695312e-08, "adv_std": 0.9999985694885254, "adv_min": -0.7823910117149353, "adv_max": 1.307485580444336, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.561122169042996, "comp_kd_mean": 0.0, "comp_total_mean": 0.561122169042996, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 79 |
+
{"rl_step": 390, "loss": 1.4901161193847656e-08, "mean_return": 0.148499995470047, "max_return": 0.593999981880188, "mean_motif_chained": 0.1485, "gnorm": 3.46451997756958e-07, "elapsed_s": 5779.177081108093, "cell_type": "OPC", "edit_type": "cell_type_transfer", "target_tf": "RUNX1", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": -1.4901161193847656e-08, "adv_std": 0.999996542930603, "adv_min": -0.4999983012676239, "adv_max": 1.4999948740005493, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.1485, "comp_kd_mean": 0.0, "comp_total_mean": 0.1485, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 80 |
+
{"rl_step": 395, "loss": -1.4901161193847656e-08, "mean_return": 0.49933701753616333, "max_return": 0.679209291934967, "mean_motif_chained": 0.49933701961622323, "gnorm": 5.2386894822120667e-08, "elapsed_s": 5821.533007621765, "cell_type": "End", "edit_type": "cell_type_transfer", "target_tf": "NFIA", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 1.4901161193847656e-08, "adv_std": 0.9999967813491821, "adv_min": -1.49918794631958, "adv_max": 0.5400407910346985, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.49933701961622323, "comp_kd_mean": 0.0, "comp_total_mean": 0.49933701961622323, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 81 |
+
{"rl_step": 400, "loss": -0.0, "mean_return": 0.0, "max_return": 0.0, "mean_motif_chained": 0.0, "gnorm": 0.0, "elapsed_s": 5863.650208950043, "cell_type": "Oli", "edit_type": "promoter_retarget", "target_tf": "NKX2-2", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.0, "adv_min": 0.0, "adv_max": 0.0, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.0, "comp_kd_mean": 0.0, "comp_total_mean": 0.0, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 82 |
+
{"rl_step": 405, "loss": -1.4901161193847656e-08, "mean_return": 0.16810430586338043, "max_return": 0.6724172234535217, "mean_motif_chained": 0.16810430175, "gnorm": 9.359791874885559e-08, "elapsed_s": 5910.250151395798, "cell_type": "Ex", "edit_type": "promoter_retarget", "target_tf": "MEF2C", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 1.4901161193847656e-08, "adv_std": 0.9999969601631165, "adv_min": -0.4999984800815582, "adv_max": 1.499995470046997, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.16810430175, "comp_kd_mean": 0.0, "comp_total_mean": 0.16810430175, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 83 |
+
{"rl_step": 410, "loss": -0.0, "mean_return": 0.16311143338680267, "max_return": 0.6524457335472107, "mean_motif_chained": 0.16311143588372323, "gnorm": 7.729977369308472e-08, "elapsed_s": 5952.6239812374115, "cell_type": "In", "edit_type": "promoter_retarget", "target_tf": "DLX2", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.9999969005584717, "adv_min": -0.49999845027923584, "adv_max": 1.4999953508377075, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.16311143588372323, "comp_kd_mean": 0.0, "comp_total_mean": 0.16311143588372323, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 84 |
+
{"rl_step": 415, "loss": -0.0, "mean_return": 0.0, "max_return": 0.0, "mean_motif_chained": 0.0, "gnorm": 0.0, "elapsed_s": 5994.884898900986, "cell_type": "Ast", "edit_type": "promoter_retarget", "target_tf": "NFIA", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.0, "adv_min": 0.0, "adv_max": 0.0, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.0, "comp_kd_mean": 0.0, "comp_total_mean": 0.0, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 85 |
+
{"rl_step": 420, "loss": -1.4901161193847656e-08, "mean_return": 0.477896511554718, "max_return": 1.911586046218872, "mean_motif_chained": 0.47789651497499996, "gnorm": 2.1513551473617554e-07, "elapsed_s": 6037.3054938316345, "cell_type": "Oli", "edit_type": "promoter_retarget", "target_tf": "SOX10", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 1.4901161193847656e-08, "adv_std": 0.999998927116394, "adv_min": -0.499999463558197, "adv_max": 1.4999984502792358, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.47789651497499996, "comp_kd_mean": 0.0, "comp_total_mean": 0.47789651497499996, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 86 |
+
{"rl_step": 425, "loss": -0.0, "mean_return": 0.0, "max_return": 0.0, "mean_motif_chained": 0.0, "gnorm": 0.0, "elapsed_s": 6079.569129705429, "cell_type": "Ast", "edit_type": "cell_type_transfer", "target_tf": "MEF2C", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.0, "adv_min": 0.0, "adv_max": 0.0, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.0, "comp_kd_mean": 0.0, "comp_total_mean": 0.0, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 87 |
+
{"rl_step": 430, "loss": -0.0, "mean_return": 0.0, "max_return": 0.0, "mean_motif_chained": 0.0, "gnorm": 0.0, "elapsed_s": 6121.785610198975, "cell_type": "Mic", "edit_type": "cell_type_transfer", "target_tf": "NFIA", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.0, "adv_min": 0.0, "adv_max": 0.0, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.0, "comp_kd_mean": 0.0, "comp_total_mean": 0.0, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 88 |
+
{"rl_step": 435, "loss": -0.0, "mean_return": 0.0, "max_return": 0.0, "mean_motif_chained": 0.0, "gnorm": 0.0, "elapsed_s": 6164.1565363407135, "cell_type": "Oli", "edit_type": "cell_type_transfer", "target_tf": "ERG", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.0, "adv_min": 0.0, "adv_max": 0.0, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.0, "comp_kd_mean": 0.0, "comp_total_mean": 0.0, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 89 |
+
{"rl_step": 440, "loss": -0.0, "mean_return": 0.0, "max_return": 0.0, "mean_motif_chained": 0.0, "gnorm": 0.0, "elapsed_s": 6206.257404088974, "cell_type": "Ex", "edit_type": "promoter_retarget", "target_tf": "NEUROD2", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.0, "adv_min": 0.0, "adv_max": 0.0, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.0, "comp_kd_mean": 0.0, "comp_total_mean": 0.0, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 90 |
+
{"rl_step": 445, "loss": 4.470348358154297e-08, "mean_return": 0.49774038791656494, "max_return": 1.3385157585144043, "mean_motif_chained": 0.49774037176744645, "gnorm": 6.891787052154541e-08, "elapsed_s": 6248.725491762161, "cell_type": "End", "edit_type": "promoter_retarget", "target_tf": "KLF2", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": -4.470348358154297e-08, "adv_std": 0.9999982714653015, "adv_min": -0.778501570224762, "adv_max": 1.315032720565796, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.49774037176744645, "comp_kd_mean": 0.0, "comp_total_mean": 0.49774037176744645, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 91 |
+
{"rl_step": 450, "loss": -1.4901161193847656e-08, "mean_return": 0.3447675108909607, "max_return": 0.6930000185966492, "mean_motif_chained": 0.3447675, "gnorm": 4.1676685214042664e-08, "elapsed_s": 6290.909668445587, "cell_type": "Oli", "edit_type": "activity_boost", "target_tf": "NKX2-2", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 1.4901161193847656e-08, "adv_std": 0.9999974370002747, "adv_min": -0.866001307964325, "adv_max": 0.8747048377990723, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.3447675, "comp_kd_mean": 0.0, "comp_total_mean": 0.3447675, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 92 |
+
{"rl_step": 455, "loss": 2.9802322387695312e-08, "mean_return": 0.40657228231430054, "max_return": 0.9605960249900818, "mean_motif_chained": 0.40657226123249995, "gnorm": 3.3527612686157227e-07, "elapsed_s": 6333.3316423892975, "cell_type": "In", "edit_type": "cell_type_transfer", "target_tf": "STAT3", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": -2.9802322387695312e-08, "adv_std": 0.9999979734420776, "adv_min": -0.8388785719871521, "adv_max": 1.143114447593689, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.40657226123249995, "comp_kd_mean": 0.0, "comp_total_mean": 0.40657226123249995, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 93 |
+
{"rl_step": 460, "loss": -0.0, "mean_return": 0.5743361711502075, "max_return": 1.6181353330612183, "mean_motif_chained": 0.5743361619767475, "gnorm": 1.73225998878479e-07, "elapsed_s": 6375.471252918243, "cell_type": "In", "edit_type": "cell_type_transfer", "target_tf": "MEF2C", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.9999986886978149, "adv_min": -0.7497912645339966, "adv_max": 1.3626714944839478, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.5743361619767475, "comp_kd_mean": 0.0, "comp_total_mean": 0.5743361619767475, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 94 |
+
{"rl_step": 465, "loss": -1.4901161193847656e-08, "mean_return": 0.25, "max_return": 1.0, "mean_motif_chained": 0.25, "gnorm": 1.3969838619232178e-07, "elapsed_s": 6417.580529212952, "cell_type": "Mic", "edit_type": "promoter_retarget", "target_tf": "RUNX1", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 1.4901161193847656e-08, "adv_std": 0.9999979734420776, "adv_min": -0.4999989867210388, "adv_max": 1.4999970197677612, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.25, "comp_kd_mean": 0.0, "comp_total_mean": 0.25, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 95 |
+
{"rl_step": 470, "loss": -0.0, "mean_return": 0.0, "max_return": 0.0, "mean_motif_chained": 0.0, "gnorm": 0.0, "elapsed_s": 6459.555973529816, "cell_type": "OPC", "edit_type": "promoter_retarget", "target_tf": "OLIG2", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.0, "adv_min": 0.0, "adv_max": 0.0, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.0, "comp_kd_mean": 0.0, "comp_total_mean": 0.0, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 96 |
+
{"rl_step": 475, "loss": -1.4901161193847656e-08, "mean_return": 0.38621801137924194, "max_return": 0.7840800285339355, "mean_motif_chained": 0.38621800998, "gnorm": 1.8998980522155762e-07, "elapsed_s": 6501.703873634338, "cell_type": "Mic", "edit_type": "cell_type_transfer", "target_tf": "SOX9", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 1.4901161193847656e-08, "adv_std": 0.9999976754188538, "adv_min": -0.8658266663551331, "adv_max": 0.891930341720581, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.38621800998, "comp_kd_mean": 0.0, "comp_total_mean": 0.38621800998, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 97 |
+
{"rl_step": 480, "loss": -0.0, "mean_return": 0.30292123556137085, "max_return": 1.2116849422454834, "mean_motif_chained": 0.30292123806977167, "gnorm": 7.497146725654602e-08, "elapsed_s": 6543.623281478882, "cell_type": "OPC", "edit_type": "promoter_retarget", "target_tf": "ASCL1", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.9999983310699463, "adv_min": -0.49999916553497314, "adv_max": 1.4999974966049194, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.30292123806977167, "comp_kd_mean": 0.0, "comp_total_mean": 0.30292123806977167, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 98 |
+
{"rl_step": 485, "loss": -1.4901161193847656e-08, "mean_return": 0.3397590219974518, "max_return": 1.3590360879898071, "mean_motif_chained": 0.33975902614517495, "gnorm": 2.384185791015625e-07, "elapsed_s": 6585.789341449738, "cell_type": "Oli", "edit_type": "activity_boost", "target_tf": "NKX2-2", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 1.4901161193847656e-08, "adv_std": 0.9999985694885254, "adv_min": -0.4999992549419403, "adv_max": 1.499997854232788, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.33975902614517495, "comp_kd_mean": 0.0, "comp_total_mean": 0.33975902614517495, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 99 |
+
{"rl_step": 490, "loss": -0.0, "mean_return": 0.0, "max_return": 0.0, "mean_motif_chained": 0.0, "gnorm": 0.0, "elapsed_s": 6627.789257287979, "cell_type": "Oli", "edit_type": "promoter_retarget", "target_tf": "OLIG2", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.0, "adv_min": 0.0, "adv_max": 0.0, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.0, "comp_kd_mean": 0.0, "comp_total_mean": 0.0, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 100 |
+
{"rl_step": 495, "loss": -0.0, "mean_return": 0.0, "max_return": 0.0, "mean_motif_chained": 0.0, "gnorm": 0.0, "elapsed_s": 6669.874458551407, "cell_type": "In", "edit_type": "activity_boost", "target_tf": "DLX2", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 0.0, "adv_std": 0.0, "adv_min": 0.0, "adv_max": 0.0, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.0, "comp_kd_mean": 0.0, "comp_total_mean": 0.0, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|
| 101 |
+
{"rl_step": 500, "loss": -1.4901161193847656e-08, "mean_return": 0.16810430586338043, "max_return": 0.6724172234535217, "mean_motif_chained": 0.16810430175, "gnorm": 1.6763806343078613e-07, "elapsed_s": 6711.886792182922, "cell_type": "In", "edit_type": "activity_boost", "target_tf": "DLX2", "kd_active": false, "kd_tf": "", "kd_score_mean": 0.0, "ratio_mean": 1.0, "ratio_min": 1.0, "ratio_max": 1.0, "log_ratio_mean": 0.0, "adv_mean": 1.4901161193847656e-08, "adv_std": 0.9999969601631165, "adv_min": -0.4999984800815582, "adv_max": 1.499995470046997, "comp_oracle_mean": 0.0, "comp_motif_chained_mean": 0.16810430175, "comp_kd_mean": 0.0, "comp_total_mean": 0.16810430175, "_algo": "dapo", "_lora_r": 16, "_peak_lr": 1e-05, "_temperature": 1.0, "_seq_len_mean": 360.0}
|