Add six MARRI checkpoints and model card

README.md

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 ---
 license: cc-by-4.0
+tags:
+- rna
+- rna-rna-interaction
+- pytorch
 ---
+
+# MARRI model checkpoints
+
+Trained checkpoints for MARRI (mechanism-aware multimodal framework for RNA--RNA
+interaction prediction). All checkpoints share the same architecture (RNA-FM +
+RNet-2D dual-tower encoder, opening branch, hybridization-gain MLP, axial
+cross-attention classifier) and the same backbone configuration -- RNA-FM
+fine-tuned, RNet-2D frozen, epoch-wise dynamic negative resampling -- differing
+only in random seed and/or training data split.
+
+Code: [**https://github.com/Gardeina/MARRI**](https://github.com/Gardeina/MARRI)
+Interpretability/attention export for the headline model: https://huggingface.co/datasets/Xu-AI4Science/MARRI-interpretability
+
+Each `.pth` file is a raw `state_dict()` for the interaction model (not a full
+training checkpoint with optimizer state), loadable via
+`model.load_state_dict(torch.load(path, map_location=device))`.
+
+## Main-matrix checkpoints (N-clean dataset, random 8:1:1 split)
+
+| File | Seed | Test ROC-AUC | Best epoch | Notes |
+|---|---|---|---|---|
+| `dyn_ft-rnafm_seed42/best_rna_physics_model.pth` | 42 | 0.7530 | 23 | **Headline model**, reported as the main MARRI result throughout the paper |
+| `dyn_ft-rnafm_seed43/best_rna_physics_model.pth` | 43 | 0.7409 | 15 | Seed-repeat run, same recipe |
+| `dyn_ft-rnafm_seed44/best_rna_physics_model.pth` | 44 | 0.7342 | 18 | Seed-repeat run, same recipe |
+
+Mean +/- SD over these three seeds: ROC-AUC 0.7427 +/- 0.0095 (Table 1 in the paper).
+
+## Leakage-resistant held-out generalization checkpoints (seed 42, own data split each)
+
+Same recipe, each retrained from scratch on its own leakage-resistant held-out
+split (a separate positive/negative pool per split, not the main N-clean
+dataset -- see Methods/Supplementary for split construction).
+
+| File | Held-out split | Test ROC-AUC | Best epoch |
+|---|---|---|---|
+| `generalization_interaction_pair_seed42/best_rna_physics_model.pth` | Unseen RNA--RNA pair | 0.7422 | 14 |
+| `generalization_transcript_seed42/best_rna_physics_model.pth` | Unseen RNA/gene (most stringent) | 0.6630 | 13 |
+| `generalization_interaction_locus_seed42/best_rna_physics_model.pth` | Unseen local interaction locus | 0.7502 | 19 |
+
+These three correspond to Table 4 ("Generalization under leakage-resistant
+held-out splits") in the paper.
+
+## Citation
+
+Publication metadata will be updated when available.
+
+```bibtex
+@article{MARRI_TBD,
+  title   = {MARRI: A Mechanism-Aware Multimodal Learning Framework for RNA--RNA Interaction Prediction},
+  author  = {AUTHOR_LIST_TBD},
+  journal = {JOURNAL_TBD},
+  year    = {YEAR_TBD},
+  doi     = {DOI_TBD}
+}
+```
+
+## Contact
+
+For questions about MARRI, please contact **2300393032@szu.edu.cn**.

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