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Oct 28

Learning When to Collaborate: Selective Multi-Agent Medical Reasoning via Uncertainty-Aware Routing

Multi-agent systems have emerged as a promising paradigm for multimodal medical reasoning, but existing methods rely on two assumptions that hinder practical deployment: (i) always-active dense collaboration among multiple agents, and (ii) dependence on large cloud-based models that raise privacy and efficiency concerns. In this paper, we challenge both assumptions and propose SMART-Med, a fully local multi-agent method that treats collaboration as a learnable decision rather than a default behavior. Our key insight is that not every medical query requires costly multi-agent deliberation: many can be reliably solved by a single well-trained agent, while only uncertain cases benefit from expert collaboration. Based on this insight, SMART-Med introduces an uncertainty-driven routing mechanism that adaptively decides when to answer directly and when to recruit a small subset of expert agents, effectively converting dense multi-agent reasoning into selective, query-adaptive coordination. To make this routing reliable, we curate a new multimodal medical dataset MedVR-3K with high-quality reasoning traces and a difficulty hierarchy, and then fine-tune local agents using GRPO with two complementary rewards: a certainty-aware accuracy reward and a vision-language reward model for correctness and reasoning quality respectively. Experiments on four medical visual question answering benchmarks show that SMART-Med achieves competitive performance compared to existing MAS approaches while substantially reducing inference cost (reducing inference time by more than 3.8x and token usage by 72%). Moreover, after fine-tuning on MedVR-3K, SMART-Med yields an average improvement of 6.7% across Slake, PathVQA, VQA-RAD, and PMC-VQA.

  • 4 authors
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Oct 23

UniH$^3$: Unifying Hierarchical Homogeneity and Heterogeneity for All-in-One Medical Image Restoration

All-in-One medical image restoration (MedIR) aims to address diverse tasks across modalities and degradation types using a single universal model. Existing methods typically prioritize modeling inter-task heterogeneity (e.g., distinct data distributions and degradation types). However, they largely neglect the inherent homogeneity present in medical images, such as widely shared anatomical structures within and across modalities, which can be leveraged to ease model training and improve generalization. To this end, we propose UniH3, a novel framework that Unifies Hierarchical Homogeneity and Heterogeneity for all-in-one medical image restoration. Specifically, to comprehensively exploit homogeneity, we introduce a Hierarchical Homogeneity Memory (H2M) module that progressively distills intra- and inter-task homogeneity priors from high-quality images during training, and adaptively retrieves the most relevant priors tailored to the input for guided restoration. These retrieved priors are then injected into the restoration pipeline via an efficient Homogeneity-Guided Attention (HGA) mechanism. Furthermore, to comprehensively address heterogeneity, we design a Hierarchical Heterogeneity Balancer (H2B) that mitigates both inter- and intra-task conflicts during optimization, facilitating balanced and effective multi-task learning. Extensive experiments on two large-scale benchmarks, MedIR-2D-500K and MedIR-3D-3K, demonstrate that UniH3 achieves state-of-the-art performance on both all-in-one and single-task medical image restoration. We hope this work establishes a strong benchmark and advances the development of general-purpose medical image restoration models. Code is available at https://github.com/Yaziwel/UniH3.