Daily Papers

Vaccine supply chain optimization can benefit from hierarchical time series forecasting, when grouping the vaccines by type or location. However, forecasts of different hierarchy levels become incoherent when higher levels do not match the sum of the lower levels forecasts, which can be addressed by reconciliation methods. In this paper, we tackle the vaccine sale forecasting problem by modeling sales data from GSK between 2010 and 2021 as a hierarchical time series. After forecasting future values with several ARIMA models, we systematically compare the performance of various reconciliation methods, using statistical tests. We also compare the performance of the forecast before and after COVID. The results highlight Minimum Trace and Weighted Least Squares with Structural scaling as the best performing methods, which provided a coherent forecast while reducing the forecast error of the baseline ARIMA.

We carefully evaluate a number of algorithms for learning in a federated environment, and test their utility for a variety of image classification tasks. We consider many issues that have not been adequately considered before: whether learning over data sets that do not have diverse sets of images affects the results; whether to use a pre-trained feature extraction "backbone"; how to evaluate learner performance (we argue that classification accuracy is not enough), among others. Overall, across a wide variety of settings, we find that vertically decomposing a neural network seems to give the best results, and outperforms more standard reconciliation-used methods.

Multimodal Retrieval-Augmented Generation (MMRAG) has been introduced to enhance Multimodal Large Language Models by incorporating externally retrieved multimodal knowledge, but it introduces two challenges: Parametric-Retrieved Knowledge Inconsistency (PRKI), where discrepancies between parametric and retrieved knowledge create uncertainty in determining reliability, and Visual-Textual Knowledge Inconsistency (VTKI), where misalignment between visual and textual sources disrupts entity representation. To address these challenges, we propose Cross-source knowledge Reconciliation for Multimodal RAG (CoRe-MMRAG), a novel end-to-end framework that effectively reconciles inconsistencies across knowledge sources. CoRe-MMRAG follows a four-stage pipeline: it first generates an internal response from parametric knowledge, then selects the most relevant multimodal evidence via joint similarity assessment, generates an external response, and finally integrates both to produce a reliable answer. Additionally, a specialized training paradigm enhances knowledge source discrimination, multimodal integration, and unified answer generation. Experiments on KB-VQA benchmarks show that CoRe-MMRAG achieves substantial improvements over baseline methods, achieving 5.6% and 9.3% performance gains on InfoSeek and Encyclopedic-VQA, respectively.

Cloud infrastructure is managed through a mix of interfaces -- traditionally, cloud consoles, command-line interfaces (CLI), and SDKs are the tools of choice. Recently, Infrastructure-as-Code/IaC frameworks (e.g., Terraform) have quickly gained popularity. Unlike conventional tools, IaC~frameworks encode the infrastructure in a "source-of-truth" configuration. They are capable of automatically carrying out modifications to the cloud -- deploying, updating, or destroying resources -- to bring the actual infrastructure into alignment with the IaC configuration. However, when IaC is used alongside consoles, CLIs, or SDKs, it loses visibility into external changes, causing infrastructure drift, where the configuration becomes outdated, and later IaC operations may undo valid updates or trigger errors. We present NSync, an automated system for IaC reconciliation that propagates out-of-band changes back into the IaC program. Our key insight is that infrastructure changes eventually all occur via cloud API invocations -- the lowest layer for cloud management operations. NSync gleans insights from API traces to detect drift (i.e., non-IaC changes) and reconcile it (i.e., update the IaC configuration to capture the changes). It employs an agentic architecture that leverages LLMs to infer high-level intents from noisy API sequences, synthesize targeted IaC updates using specialized tools, and continually improve through a self-evolving knowledge base of past reconciliations. We further introduce a novel evaluation pipeline for injecting realistic drifts into cloud infrastructure and assessing reconciliation performance. Experiments across five real-world Terraform projects and 372 drift scenarios show that NSync outperforms the baseline both in terms of accuracy (from 0.71 to 0.97 pass@3) and token efficiency (1.47times improvement).

Medication reconciliation at clinical handoffs is a high-stakes, error-prone process. Large language models are increasingly proposed to assist with this task using FHIR-structured patient records, but a fundamental and largely unstudied variable is how the FHIR data is serialised before being passed to the model. We present the first systematic comparison of four FHIR serialisation strategies (Raw JSON, Markdown Table, Clinical Narrative, and Chronological Timeline) across five open-weight models (Phi-3.5-mini, Mistral-7B, BioMistral-7B, Llama-3.1-8B, Llama-3.3-70B) on a controlled benchmark of 200 synthetic patients, totalling 4,000 inference runs. We find that serialisation strategy has a large, statistically significant effect on performance for models up to 8B parameters: Clinical Narrative outperforms Raw JSON by up to 19 F1 points for Mistral-7B (r = 0.617, p < 10^{-10}). This advantage reverses at 70B, where Raw JSON achieves the best mean F1 of 0.9956. In all 20 model and strategy combinations, mean precision exceeds mean recall: omission is the dominant failure mode, with models more often missing an active medication than fabricating one, which changes how clinical safety auditing priorities should be set. Smaller models plateau at roughly 7-10 concurrent active medications, leaving polypharmacy patients, the patients most at risk from reconciliation errors, systematically underserved. BioMistral-7B, a domain-pretrained model without instruction tuning, produces zero usable output in all conditions, showing that domain pretraining alone is not sufficient for structured extraction. These results offer practical, evidence-based format recommendations for clinical LLM deployment: Clinical Narrative for models up to 8B, Raw JSON for 70B and above. The complete pipeline is reproducible on open-source tools running on an AWS g6e.xlarge instance (NVIDIA L40S, 48 GB VRAM).

Seven years ago, researchers proposed a postprocessing method to equalize the error rates of a model across different demographic groups. The work launched hundreds of papers purporting to improve over the postprocessing baseline. We empirically evaluate these claims through thousands of model evaluations on several tabular datasets. We find that the fairness-accuracy Pareto frontier achieved by postprocessing contains all other methods we were feasibly able to evaluate. In doing so, we address two common methodological errors that have confounded previous observations. One relates to the comparison of methods with different unconstrained base models. The other concerns methods achieving different levels of constraint relaxation. At the heart of our study is a simple idea we call unprocessing that roughly corresponds to the inverse of postprocessing. Unprocessing allows for a direct comparison of methods using different underlying models and levels of relaxation.

The alignment of Large Language Models (LLMs) with human values is central to their safe deployment, yet current practice produces static, brittle, and costly-to-maintain models that fail to keep pace with evolving norms and policies. This misalignment, which we term the Alignment-Reality Gap, poses a growing challenge for reliable long-term use. Existing remedies are inadequate: large-scale re-annotation is economically prohibitive, and standard unlearning methods act as blunt instruments that erode utility rather than enable precise policy updates. We introduce TRACE (Triage and Re-align by Alignment Conflict Evaluation), a framework for principled unlearning that reconceives re-alignment as a programmatic policy application problem. TRACE programmatically triages existing preference data against a new policy, identifies high-impact conflicts via a alignment impact score, and applies a hybrid optimization that cleanly inverts, discards, or preserves preferences while safeguarding model performance. Empirical results show that TRACE achieves robust re-alignment across diverse model families (Qwen2.5-7B, Gemma-2-9B, Llama-3.1-8B). On both synthetic benchmarks and the PKU-SafeRLHF dataset under complex policy shift, TRACE enforces new principles without degrading general capabilities. Our work establishes a scalable, dynamic, and cost-effective paradigm for maintaining LLM alignment, providing a foundation for sustainable and responsible AI deployment.