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Nov 9

ResidencyRL: Reinforcement Learning in Simulated Clinical Environments

In medical education, physicians convert academic knowledge into clinical expertise through residency: years of training across thousands of encounters, with diverse sources of feedback and progressively greater autonomy. Much of clinical reasoning relies on the patient encounter, a dialogue in which a clinician elicits history, refines diagnostic hypotheses, and decides management under uncertainty. While large language models (LLMs) excel on static medical benchmarks, methods to optimize the full sequence of clinical decisions remain underdeveloped. We present ResidencyRL, a reinforcement learning (RL) method for training clinical artificial intelligence (AI) agents through simulated multi-turn clinical encounters (up to 60 dialogue turns and 8 tool calls per trajectory). ResidencyRL pairs the policy agent with LLM simulators capable of complex, adversarial behaviors, training against a structured reward aligned to diagnostic accuracy, management quality, communication, documentation, and safety. On held-out evaluations, the ResidencyRL agent improves diagnostic accuracy by 7.0% under adversarial conditions (88.0% vs. 81.0%) and reduces missed red flag rates by 31%, demonstrating rigorous mitigation of premature closure. Blinded expert clinicians validated these gains, preferring the trained agent in 87.6% of side-by-side comparisons. The procedural competencies transfer to unseen benchmarks: the agent outperforms the base model across all six clinical axes of the AMIE multi-visit benchmark, and shows consistent directional improvements on AgentClinic and CRAFT-MD. Our findings demonstrate that sequential clinical decision-making can be effectively learned through multi-turn RL in simulation, yielding robust, generalizable capabilities, paving the way towards clinical mastery. Prospective validation with real-world workflows remains necessary to establish clinical utility.

  • 35 authors
·
Aug 6

Rollplex: Cross-Phase GPU Spatial Sharing for Vision Language Model Post-Training

Vision-language models (VLMs) enable embodied agents to reason and act from visual observations and language instructions. Reinforcement learning (RL) post-training enhances these capabilities using task feedback, but current on-policy RL runtimes execute rollout, reference scoring, and actor training in strict serial phases. While effective for text-only RL, this phase-granular execution is wasteful for VLMs, where processing dense video inputs and prompt prefixes occupies a large fraction of each phase. Because prefix processing is independent of the generated response, it can be run alongside rollout decoding, which leaves GPU compute capacity underutilized, without breaking synchronous on-policy semantics. We present Rollplex, a runtime that decomposes the reference and training phase and moves the prefix computation into the rollout decode window. Realizing this schedule requires more than concurrent kernel launches: naive colocation of Qwen2.5-VL-32\,B requires roughly 165\,GiB per GPU, while rollout and training prefer different tensor-parallel (TP) degrees and weight layouts. Rollplex addresses these constraints with two mechanisms. Phase-aware memory management controls HBM residency according to producer--consumer lifetimes. Parallelism-aware weight sharing uses the same physical storage for layout-compatible tensors across distinct TP degrees and reconstructs only incompatible tensors, avoiding a complete second actor copy. On 32 H800 GPUs, Rollplex achieves 1.23times--1.30times speedup over serial colocation and 1.57times--2.24times over disaggregation under the same GPU budget, while preserving the synchronous RL update.

  • 11 authors
·
Aug 13

How Much Does the Hint Matter? Scope Conditions for Hindsight Self-Distillation in Financial Reasoning

Financial institutions operating under data-residency constraints are restricted to open-weight models small enough to locally host, which trail frontier systems on multi-step quantitative reasoning. On-policy distillation narrows such gaps by supervising a student on its own rollouts, but traditional OPD requires a strong external teacher, and on-policy self-distillation (OPSD) conditions on a full reference solution. We ask how much of that signal is necessary. We present Fin-SD, a localized hindsight self-distillation recipe for multi-step reasoning. Given a problem the student fails, the student itself identifies the first incorrect reasoning step and writes a short critique of that step. We truncate the student's trajectory immediately before the error (aiming to obtain a correct prefix), condition a frozen copy of the student on the same prefix plus the hint, and distill that hint-conditioned teacher into the student over a short rollout under reverse KL. No external model contributes a gradient. We apply Fin-SD to GPT-OSS-20B on a custom multi-step financial reasoning benchmark that requires deriving formula inputs from realistic scenarios via accounting conventions. We find: (i) replacing the critique with a generic-feedback control matches Fin-SD's entire 3.03 pp accuracy gain over the base model on the FinanceReasoning Hard subset, suggesting the gain comes from where supervision is applied, not hint content; (ii) the model writing the hint does not need to be stronger than the model receiving it: hints from same-family GPT-OSS-120B, at roughly 6x the parameters, yield no materially greater benefits than self-written hints; and (iii) Fin-SD matches on-policy self-distillation from full reference solutions on accuracy while generating 9.5% fewer tokens. With Fin-SD, general reasoning on MMLU-Pro and a fourteen-metric compliance audit on FinTrust show no material regression.

ctgt-inc CTGT, Inc.
·
Oct 25 2

HealthQA-BR: A System-Wide Benchmark Reveals Critical Knowledge Gaps in Large Language Models

The evaluation of Large Language Models (LLMs) in healthcare has been dominated by physician-centric, English-language benchmarks, creating a dangerous illusion of competence that ignores the interprofessional nature of patient care. To provide a more holistic and realistic assessment, we introduce HealthQA-BR, the first large-scale, system-wide benchmark for Portuguese-speaking healthcare. Comprising 5,632 questions from Brazil's national licensing and residency exams, it uniquely assesses knowledge not only in medicine and its specialties but also in nursing, dentistry, psychology, social work, and other allied health professions. We conducted a rigorous zero-shot evaluation of over 20 leading LLMs. Our results reveal that while state-of-the-art models like GPT 4.1 achieve high overall accuracy (86.6%), this top-line score masks alarming, previously unmeasured deficiencies. A granular analysis shows performance plummets from near-perfect in specialties like Ophthalmology (98.7%) to barely passing in Neurosurgery (60.0%) and, most notably, Social Work (68.4%). This "spiky" knowledge profile is a systemic issue observed across all models, demonstrating that high-level scores are insufficient for safety validation. By publicly releasing HealthQA-BR and our evaluation suite, we provide a crucial tool to move beyond single-score evaluations and toward a more honest, granular audit of AI readiness for the entire healthcare team.

  • 1 authors
·
Jun 16, 2025

SPHERICAL KV: Angle-Domain Attention and Rate-Distortion Retention for Efficient Long-Context Inference

Long-context inference is increasingly constrained by the KV cache: resident memory grows with context length, and decoding becomes limited by repeated High Bandwidth Memory (HBM) streaming rather than arithmetic. Existing methods such as eviction, windowing, quantization, and offloading reduce footprint, but often leave the critical-path bottleneck only partially addressed, especially when compressed states must still be reconstructed into dense vectors during decoding. We present Spherical KV, a long-context inference method that treats KV allocation as a rate-distortion problem grounded in attention geometry for efficient decoding. The method is built on two ideas: (i) represent directional information cheaply in the decode hot loop, and (ii) allocate retention and precision according to estimated future utility. Its first component, Angle-Domain Attention (ADA), stores keys in a spherical parameterization consisting of a scalar radius and compact angle codes, and computes attention logits directly from these codes without reconstructing dense keys. This preserves a paged, block-local, fusion-friendly decode path and directly targets HBM traffic in realistic serving settings. Its second component, Rate-Distortion Retention (RDR), jointly chooses keep/drop decisions and precision tiers per token and head under a fixed budget, producing tier-homogeneous pages with lightweight metadata and coalesced reads. Together, ADA and RDR provide a deployment-oriented mechanism for reducing KV residency while preserving decode efficiency.

  • 7 authors
·
May 12

ComplianceGate: Classifier-Gated Multi-Tier LLM Routing for Inference in Regulated Industries

Large language models deployed in regulated industries operate under two constraints: compliance enforcement and cost efficiency. Personally identifiable information (PII) in user queries can reach model endpoints before the system determines whether that data should leave its jurisdictional boundary. Serving all queries through a single large model consumes full GPU capacity regardless of query complexity while offering no mechanism for geographic routing. Mixture-of-Experts architectures do not address this routing occurs between expert layers within the model after data has already arrived at the endpoint, with all experts loaded in memory regardless of query complexity. We propose a classifier-gated routing architecture that enforces compliance by design. A trained encoder classifier sits before any decoder inference, evaluating each query for complexity and data sensitivity, then routing it to an appropriately sized dense model in the appropriate geographic location. PII-containing queries route to local endpoints before any LLM computation begins, making data residency violations structurally impossible. Simple queries reach small, fast models at a fraction of the cost. Our evaluation on 600 queries demonstrates 39% median latency reduction, 33-52% cost savings depending on query distribution, and generation throughput of 122-200 tokens/second versus 50-64 for the baseline. The encoder classifier achieves 99.2% accuracy with near-perfect PII recall at 7ms inference overhead, establishing pre-inference classification as a practical path to compliance-by-design LLM deployment.

  • 1 authors
·
Jun 29

Coda: Exploiting Admission Flexibility for Coding-Agent Serving

Coding agents powered by large language models (LLMs) repeatedly alternate between model inference and tool calls, creating long-lived sessions with reusable key-value (KV) states and asynchronous request resumptions. Logical readiness, however, does not ensure efficient admission in a shared serving system. Through direct trace analysis and trace-driven replay, we identify two mismatches: reusable KV states reside across storage tiers and incur unequal computational costs for state preparation, while requests with heterogeneous context lengths can decode inefficiently together. Our central insight is that exploiting admission flexibility can improve serving performance while preserving request progress. We present Coda, a coding-agent serving system that realizes this insight through a readiness-informed admission layer incorporating two mechanisms. Tiered-Aging state admission exploits bounded flexibility in admission order to improve admission efficiency and preserve request progress. Compatibility-Aware execution admission exploits flexibility in attention grouping within each model iteration to reduce mixed-context interference and improve shared decoding efficiency. For multi-worker configurations, Coda introduces a separate routing layer that considers KV-state residency, worker load, and request-to-worker context-length compatibility to guide efficient request placement. We evaluate Coda across different models and workloads against state-of-the-art coding-agent serving systems and vLLM. Across the single-worker and multi-worker experiments, Coda improves output-token and SLO-compliant throughput by 20.3% and 70.5% on average, with peak gains of 29.3% and 140.2%.

  • 8 authors
·
Oct 1

Prefetch-Steered Routing: Deterministic Cache-Aware Expert Selection for Offloaded Mixture-of-Experts Decoding

When a Mixture-of-Experts (MoE) model does not fit in GPU memory, batch-1 decoding is dominated by copying expert weights from host memory. Cache-aware routing reduces these copies by biasing the router toward resident experts, but combined with asynchronous prefetching it makes the model's outputs depend on transfer timing, so a harness that does not simulate that timing no longer evaluates the deployed model. We propose prefetch-steered routing (PSR): routing conditions on a deterministic logical cache, into which at most n experts predicted by the next layer's router are inserted per layer and token; physical copies affect only latency. On OLMoE-1B-7B with 50% and 25% of experts resident on an RTX 4090, PSR decodes 2.2-2.3x faster than exact routing with LRU and 25-30% faster than the Cache-Prior operating point, with mean benchmark differences of +0.1 and +0.5 points (95% lower bounds -0.8 and -0.3). In greedy generation its lead over Cache-Prior depends on the workload and reverses on HumanEval at 50% residency. On Moonlight-16B-A3B, PSR is 1.9x faster than exact routing with LRU at 37.5% residency and, at the latency of Cache-Prior, significantly better on three of eight benchmarks. On Qwen3.6-35B-A3B, where copies are cheap relative to computation, PSR keeps its advantage over Cache-Prior on the likelihood benchmarks but not its speed. Distillation-trained gates did not help. Speculative decoding with block-level expert selection was slower than PSR with a 1B autoregressive drafter on OLMoE, but with a block drafter on Qwen3.6 it was 2.1-2.9x faster than any autoregressive configuration with at most its GPU memory on the 64 prompts we timed.

  • 1 authors
·
Oct 25

Profiling Large Language Model Inference on Apple Silicon: A Quantization Perspective

A systematic understanding of Apple Silicon is lacking in the current landscape of hardware efficiency; research focus is largely centered on accelerating GPUs for large-scale training or inference on CUDA devices. This paper investigates Apple Silicon's unique memory architecture that offers a unified memory integrating CPU and GPU memory and its implications for on-device LLM inference. We decipher myths about whether Apple Silicon is efficient for on-device inference compared to competitors such as NVIDIA GPUs by directly conducting latency and throughput comparison benchmarks. We explain the performance gap between them through profiling low level hardware metrics - ALU utilization, memory bandwidth, buffer usage, cache residency etc. at runtime. We draw several insights regarding performance bottlenecks such as dequantization overhead, compute throughput and memory bandwidth. We debunk existing false claims regarding large language model inference such as compressing models to lower bit precision is a defacto promise for faster inference across all hardware platforms. We find that the large unified memory enables Apple Silicon to be both cost effective and efficient against NVIDIA GPUs for ultra large language models. Our large scale evaluation on 5 hardware testbeds incorporating three Apple M-series devices: M2 Ultra, M2 Max and M4 Pro and two NVIDIA GPUs: NVIDIA RTX A6000, a multi GPU setup with 2xNVIDIA RTX A6000, 5 model scales ranging from 8B to 405B parameters and 14 quantization schemes gives an understanding of how Apple Silicon fits within the paradigm of on-device LLM inference. Our analysis reveals multiple resource interdependencies and unexpected findings, while also quantifying established insights. To the best of our knowledge, this study makes the first attempt to present a thorough characterization and analysis of Apple Silicon for on-device inference.

  • 2 authors
·
Aug 11, 2025

Large Language Models over Networks: Collaborative Intelligence under Resource Constraints

Large language models (LLMs) are transforming society, powering applications from smartphone assistants to autonomous driving. Yet cloud-based LLM services alone cannot serve a growing class of applications, including those operating under intermittent connectivity, sub-second latency budgets, data-residency constraints, or sustained high-volume inference. On-device deployment is in turn constrained by limited computation and memory. No single endpoint can deliver high-quality service across this spectrum. This article focuses on collaborative intelligence, a paradigm in which multiple independent LLMs distributed across device and cloud endpoints collaborate at the task level through natural language or structured messages. Such collaboration strives for superior response quality under heterogeneous resource constraints spanning computation, memory, communication, and cost across network tiers. We present collaborative inference along two complementary and composable dimensions: vertical device-cloud collaboration and horizontal multi-agent collaboration, which can be combined into hybrid topologies in practice. We then examine learning to collaborate, addressing the training of routing policies and the development of cooperative capabilities among LLMs. Finally, we identify open research challenges including scaling under resource heterogeneity and trustworthy collaborative intelligence.

  • 5 authors
·
May 8 1

Aloe-Vision: Robust Vision-Language Models for Healthcare

Large Vision-Language Models (LVLMs) specialized in healthcare are emerging as a promising research direction due to their potential impact in clinical and biomedical applications. However, progress is constrained by the scarcity of high-quality medical multimodal data, concerns about robustness in safety-critical settings, and the narrow and potentially contaminated evaluation benchmarks that limit reliable assessment. To address these issues, the field requires state-of-the-art solutions to be fully open and reproducible systems in which all components can be inspected, evaluated, and improved. This work introduces Aloe-Vision-Data, a large-scale, quality-filtered mixture which integrates both medical and general domains across multimodal and text-only sources, designed for direct use in model fine-tuning. Building on this dataset, we train the Aloe-Vision family of medical LVLMs, openly released with full weights, training recipes and data, in two scales (7B and 72B). Through comprehensive benchmarking, we demonstrate that high quality training mixtures produce balanced LVLMs which yield significant gains over the baseline models without compromising general capabilities, achieving competitive performance with respect to state-of-the-art alternatives. To support reliable evaluation, we introduce CareQA-Vision, a carefully curated vision benchmark derived from MIR and EIR exams, the residency entrance exams for medical and nursing specialists in Spain, offering novel vision questions with low likelihood of contamination. Finally, we show that current LVLMs remain vulnerable to adversarial and misleading inputs, underscoring reliability challenges in clinical contexts.

  • 6 authors
·
Jun 25

AGENTSERVESIM: A Hardware-aware Simulator for Multi-Turn LLM Agent Serving

Multi-turn LLM agents interleave model calls with external tool invocations, shifting serving from stateless request processing to stateful program execution. Serving these workloads requires scheduling, KV-cache management, and routing policies that use program-level context, including turn dependencies, tool-induced gaps, and reusable KV state. Evaluating such policies directly on real systems is costly, since each design point may require dedicated accelerator time across arrival rates, model scales, serving-instance counts, and memory hierarchies. Simulation offers a scalable alternative, but existing LLM serving simulators target stateless request-level workloads and therefore omit the core dynamics of agent serving: multi-turn program execution, cross-turn cache locality, and KV-cache residency during tool gaps. We present AGENTSERVESIM, a hardware-aware simulator for multi-turn LLM agent serving. AGENTSERVESIM evaluates serving policies at program granularity through composable modules: a Program Orchestrator preserves program identity and turn order, a Tool Simulator materializes tool-induced gaps, a Session-Aware Router maintains program-to-instance affinity for cache-aware dispatch, and a KV Residency Model tracks policy-defined KV placement across HBM, host DRAM/CXL, and eviction. Across real serving deployments and hardware configurations, AGENTSERVESIM reproduces real-system behavior within 6% error across key performance metrics while running entirely on commodity CPUs. These results show that AGENTSERVESIM enables controlled, repeatable exploration of agent-serving policies without requiring exhaustive deployment on costly accelerators.

  • 3 authors
·
Jun 17

GPU-Initiated Communication: Dissecting Down to the Bone

GPU-initiated communication lets GPU threads post RDMA operations directly to the NIC. It underpins NVSHMEM, NCCL GIN, and DeepEP, which serve the fine-grained, latency-critical communication of Mixture-of-Experts (MoE) models, yet its performance characteristics and optimizations remain scarcely documented beyond source code, and library comparisons fail to separate the costs of the hardware mechanism from those of the library around it. This paper dissects GPU-initiated communication at the GPU-NIC boundary. We first detail the GPU-side network path: queue placement, work-request construction, doorbell ordering, and completion semantics. We then introduce mini-gda and mini-proxy, minimal transports for the GPU and CPU-proxy submission paths, and measure them alongside NVSHMEM IBGDA, NCCL GIN, DeepEP, UCCL-EP, MSCCL++, and fabric-lib on NVIDIA H100, H200, B200, and GB200 platforms. A minimal GPU path issues an operation in 0.7 μs and completes in 4.0 μs; libraries add up to 4.6 μs of issue time through queue management, memory ordering, and completion scope, and issue time scales with the SM clock. A tuned CPU proxy matches or beats the GPU path at idle, at the cost of a dedicated core whose operating state sets its latency and throughput. On either path, sharing a queue with bulk traffic raises latency by one to three orders of magnitude. Reaching the 260 M msg/s ceiling of our InfiniBand platform requires doorbell batching and queue parallelism, and both have resource costs: communication code can reduce GPU block residency even when unused, and all-to-all traffic loses 59% of its NIC message rate at about 3,000 active connections. The submission path alone therefore does not predict communication performance. Our experiment code and results are available at https://github.com/ParCoreLab/Dissecting-GPU-Communication-Experiments.

  • 4 authors
·
Sep 30

WorldAttention: An Efficient Attention Architecture for Interactive Video World Models

Leveraging the paradigm of autoregressive diffusion, text-conditioned interactive video world models aim to simulate temporally coherent environments guided by textual instructions. While enabling low-latency, long-duration generation is pivotal for embodied AI and simulation-based planning, current frameworks primarily rely on sliding-window mechanisms to bound computational complexity. However, this approach inherently sacrifices historical context, undermining the long-range interactive capabilities. Conversely, maintaining a full-history cache remains computationally prohibitive and memory-intensive: the quadratic complexity of attention leads to excessive computational overhead, while the linear growth of the KV cache inevitably leads to GPU memory saturation. To overcome these limitations, we propose WorldAttention, a system-oriented attention architecture that achieves high efficiency through the co-design of specialized attention kernels and hierarchical KV cache management. First, we introduce Hybrid Sparse Attention (HSA), which integrates linear global attention supplemented with head-adaptive sparse attention. Additionally, we design a Hierarchical KV Cache (HKV) that organizes historical KV pairs into semantically indexed pages across multi-tier memory, enabling fine-grained retrieval and controlled GPU residency. These two designs are supported by tailored kernels to effectively translate their theoretical efficiency into real-world performance. Extensive experiments on VBench-Long and InterVBench demonstrate that WorldAttention consistently surpasses prior state-of-the-art methods, achieving subject consistency scores of 0.9472 on VBench-Long and 0.9668 on InterVBench, respectively.

Alibaba-DAMO-Academy DAMO Academy
·
Sep 27 2

Explanatory Argument Extraction of Correct Answers in Resident Medical Exams

Developing the required technology to assist medical experts in their everyday activities is currently a hot topic in the Artificial Intelligence research field. Thus, a number of large language models (LLMs) and automated benchmarks have recently been proposed with the aim of facilitating information extraction in Evidence-Based Medicine (EBM) using natural language as a tool for mediating in human-AI interaction. The most representative benchmarks are limited to either multiple-choice or long-form answers and are available only in English. In order to address these shortcomings, in this paper we present a new dataset which, unlike previous work: (i) includes not only explanatory arguments for the correct answer, but also arguments to reason why the incorrect answers are not correct; (ii) the explanations are written originally by medical doctors to answer questions from the Spanish Residency Medical Exams. Furthermore, this new benchmark allows us to setup a novel extractive task which consists of identifying the explanation of the correct answer written by medical doctors. An additional benefit of our setting is that we can leverage the extractive QA paradigm to automatically evaluate performance of LLMs without resorting to costly manual evaluation by medical experts. Comprehensive experimentation with language models for Spanish shows that sometimes multilingual models fare better than monolingual ones, even outperforming models which have been adapted to the medical domain. Furthermore, results across the monolingual models are mixed, with supposedly smaller and inferior models performing competitively. In any case, the obtained results show that our novel dataset and approach can be an effective technique to help medical practitioners in identifying relevant evidence-based explanations for medical questions.

  • 5 authors
·
Dec 1, 2023

HiSparse: Scaling Sparse-Attention Decoding with Hierarchical KV Cache Management

Top-k sparse attention makes long-context LLM decoding cheap to compute: each step reads only a few thousand selected KV entries rather than the full context. Serving systems, however, typically keep the entire KV cache in GPU HBM so that every position stays selectable, so a request's memory bill still grows with its full context length--decoding hits a capacity wall long before it runs out of compute, and a context whose KV cache exceeds HBM cannot be served at all. We present HiSparse, an exact, indexer-agnostic hierarchical KV cache for sparse-attention serving. HiSparse keeps each request's full KV history in host memory and bounds its decode footprint with a small, fixed-size GPU cache; a fused CUDA kernel resolves each layer's selections--hit detection, LRU replacement, and host-to-device fetches--inside the decode CUDA graph; and, for models that share selections across layers, exact layer-wise prefetching hides roughly half of the remaining miss overhead. Because only KV placement changes, model outputs are unchanged. HiSparse is merged into upstream SGLang and evaluated across three sparse-attention families (DSA, NSA, and Quest) on H200, B200, and GH200 platforms: it improves peak generation throughput by up to 4.7x on long-context workloads while preserving comparable per-token latency and reducing time-to-first-token at high load--and a no-IO oracle shows the resolution mechanism itself adds no measurable per-token cost, leaving host-device IO as the only price of bounded residency.

  • 6 authors
·
Aug 6